UY37032A - HETEROARILBENZIMIDAZOL COMPOUNDS - Google Patents

HETEROARILBENZIMIDAZOL COMPOUNDS

Info

Publication number
UY37032A
UY37032A UY0001037032A UY37032A UY37032A UY 37032 A UY37032 A UY 37032A UY 0001037032 A UY0001037032 A UY 0001037032A UY 37032 A UY37032 A UY 37032A UY 37032 A UY37032 A UY 37032A
Authority
UY
Uruguay
Prior art keywords
compounds
heteroarilbenzimidazol
preparing
pharmaceutical compositions
heteroarylbenzimidazole
Prior art date
Application number
UY0001037032A
Other languages
Spanish (es)
Inventor
Horst Irlbacher Dr
Wilhelm Bone Dr
Volker Schulze Dr
Tobias Heinrich Dr
Julien Lefranc Dr
Anne Mengel Dra
Florian Prinz Dr
Antje Wengner Dra
Clara Christ Dra
Roman Hillig Dr
Joszef Bálint Dr
Hans Briem Dr
Ulf Bömer Dr
Detlef Stöckigt Dr
Philip Lienau Dr
Knut Eis Dr
Marcus Koppitz Dr
Benjamin Bader Dr
Jens Schröder Dr
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of UY37032A publication Critical patent/UY37032A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Abstract

La presente invención abarca compuestos heteroarilbenzimidazol de fórmula general (I): en donde R1, R2, R3, R4 y R5 son como se definen en la presente, métodos para preparar dichos compuestos, compuestos intermediarios útiles para preparar dichos compuestos, composiciones farmacéuticas y combinaciones que comprenden dichos compuestos y el uso de dichos compuestos para fabricar composiciones farmacéuticas para el tratamiento o la profilaxis de enfermedades, en particular de trastornos hiperproliferativos y/o inflamatorios, como agente único o en combinación con otros ingredientes activos.The present invention encompasses heteroarylbenzimidazole compounds of general formula (I): wherein R1, R2, R3, R4 and R5 are as defined herein, methods for preparing said compounds, intermediates useful for preparing said compounds, pharmaceutical compositions and combinations which comprise said compounds and the use of said compounds to manufacture pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular hyperproliferative and / or inflammatory disorders, as a single agent or in combination with other active ingredients.

UY0001037032A 2015-12-18 2016-12-16 HETEROARILBENZIMIDAZOL COMPOUNDS UY37032A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15201230 2015-12-18
EP16160885 2016-03-17
EP16193418 2016-10-12

Publications (1)

Publication Number Publication Date
UY37032A true UY37032A (en) 2017-07-31

Family

ID=57882041

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001037032A UY37032A (en) 2015-12-18 2016-12-16 HETEROARILBENZIMIDAZOL COMPOUNDS

Country Status (2)

Country Link
TW (1) TW201726657A (en)
UY (1) UY37032A (en)

Also Published As

Publication number Publication date
TW201726657A (en) 2017-08-01

Similar Documents

Publication Publication Date Title
NI201900041A (en) 1, 2, 4-TRIAZOLONES 2, 4, 5-TRISUSTITUIDAS
CO2018010966A2 (en) New pyrazolopyrimidine derivatives
NI201900085A (en) 2-HETEROARYL-3-OXO-2,3-DIHYDROPYRIDAZINE-4-CARBOXAMIDES
CO2020001244A2 (en) Quinoline derivatives to treat helminth infections
DOP2019000117A (en) NEW DERIVATIVES OF QUINOLINA
CO2017011851A2 (en) Novel compounds
ECSP17007538A (en) 2- (MORFOLIN-4-IL) -1,7-NAPHTHYRIDINES
UY37460A (en) 1,2,4-TRIAZOLONS WITH ANALATION IN 4 AND 5
DOP2016000253A (en) NEW COMPOUNDS
PH12017501133A1 (en) Pyrazolopyridinamines
ECSP20008441A (en) DIHYDROOXADIAZINONES
UY37705A (en) NEW BICYCLIC PIRAZOL DERIVATIVES
UY37971A (en) SUBSTITUTED MACROCYCLIC INDOL DERITATES
UY37972A (en) MACROCYCLIC INDOL DERIVATIVES SUBSTITUTED WITH CHLORINE
UY37973A (en) MACROCYCLIC INDOL DERIVATIVES
UY35848A (en) TIENOPIRIMIDINS
DOP2016000268A (en) AMIDO-AZOLE COMPOUNDS SUBSTITUTED AS TNKS1 AND/OR TNKS2 INHIBITORS
DOP2020000100A (en) NOVEL PYRAZOLO-PIRROLO-PYRIMIDINE DERIVATIVES AS P2X3 INHIBITORS
UY37444A (en) SUBSTITUTED DERIVATIVES OF 6- (1H-PIRAZOL-1-IL) PIRIMIDIN-4-AMINA AND ITS USE
UY37032A (en) HETEROARILBENZIMIDAZOL COMPOUNDS
UY36983A (en) REPLACED PIRAZOLOPIRIDINAMINS
UY34630A (en) IMIDAZOPIRIDAZINAS REPLACED WITH AMINO

Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20221212