UY35545A - Composiciones y procedimientos para inducir tolerancia inmunitaria a las proteínas factores de coag ulación - Google Patents
Composiciones y procedimientos para inducir tolerancia inmunitaria a las proteínas factores de coag ulaciónInfo
- Publication number
- UY35545A UY35545A UY0001035545A UY35545A UY35545A UY 35545 A UY35545 A UY 35545A UY 0001035545 A UY0001035545 A UY 0001035545A UY 35545 A UY35545 A UY 35545A UY 35545 A UY35545 A UY 35545A
- Authority
- UY
- Uruguay
- Prior art keywords
- procedures
- coag
- ulation
- compositions
- factory
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/37—Factors VIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Transplantation (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Abstract
En el presente documento se proporcionan conjugados para inducir tolerancia de la proteína factor de coagulación, en el que el conjugado comprende una proteína factor de coagulación o un fragmento antigénico o variante del mismo y un ligando Siglec. También se proporcionan composiciones farmaceúticas, procedimientos y kits que comprenden los conjugados.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361816790P | 2013-04-28 | 2013-04-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY35545A true UY35545A (es) | 2014-11-28 |
Family
ID=50846907
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY0001035545A UY35545A (es) | 2013-04-28 | 2014-04-28 | Composiciones y procedimientos para inducir tolerancia inmunitaria a las proteínas factores de coag ulación |
Country Status (11)
Country | Link |
---|---|
US (1) | US20160279252A1 (es) |
EP (1) | EP2991684B1 (es) |
JP (1) | JP2016519120A (es) |
CN (1) | CN105451774A (es) |
AR (1) | AR096123A1 (es) |
CA (1) | CA2910277A1 (es) |
ES (1) | ES2691041T3 (es) |
HK (1) | HK1217167A1 (es) |
TW (1) | TW201519900A (es) |
UY (1) | UY35545A (es) |
WO (1) | WO2014179184A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20160060324A1 (en) * | 2013-04-22 | 2016-03-03 | James C. Paulson | Methods and Compositions for Treating Bleeding Disorders |
EP3458085B1 (en) * | 2016-05-20 | 2022-12-07 | Octapharma AG | Glycosylated vwf fusion proteins with improved pharmacokinetics |
CN108926719B (zh) * | 2017-05-25 | 2020-09-01 | 北京格瑞特森生物医药科技有限公司 | 用c(RGD-ACP-K)修饰的长循环脂质体 |
WO2018225873A1 (ja) * | 2017-06-09 | 2018-12-13 | 協和発酵キリン株式会社 | 核酸含有ナノ粒子 |
EP3839059A1 (en) * | 2019-12-16 | 2021-06-23 | CGT Enterprises, LLC | Devices and methods for determining coagulation factor activities |
WO2024015872A2 (en) * | 2022-07-13 | 2024-01-18 | Osprey Biopharmaceuticals, Inc. | Autoantigens engineered to suppress autoimmune response |
CN116036244B (zh) * | 2023-02-24 | 2023-09-19 | 北京基科晟斯医药科技有限公司 | 培重组人凝血因子VIII-Fc融合蛋白用于治疗含抑制物的血友病A的用途 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005055946A2 (en) * | 2003-12-03 | 2005-06-23 | Neose Technologies, Inc. | Glycopegylated granulocyte colony stimulating factor |
US20060040856A1 (en) * | 2003-12-03 | 2006-02-23 | Neose Technologies, Inc. | Glycopegylated factor IX |
JP4738346B2 (ja) * | 2003-12-03 | 2011-08-03 | ノヴォ ノルディスク アー/エス | GlycoPEG化された第IX因子 |
PL1824988T3 (pl) * | 2004-11-12 | 2018-01-31 | Bayer Healthcare Llc | Ukierunkowana na miejsce modyfikacja czynnika VIII |
JP2009511082A (ja) * | 2005-10-17 | 2009-03-19 | ヘルス リサーチ インコーポレイテッド | 糖類のためのトランスフェラーゼに特異的な受容体並びにその入手及び使用方法 |
EP2461821A4 (en) * | 2009-07-31 | 2013-07-03 | Bayer Healthcare Llc | MODIFIED POLYPEPTIDES OF FACTOR IX AND USES THEREOF |
-
2014
- 2014-04-25 TW TW103115001A patent/TW201519900A/zh unknown
- 2014-04-27 JP JP2016510820A patent/JP2016519120A/ja active Pending
- 2014-04-27 CN CN201480032984.XA patent/CN105451774A/zh active Pending
- 2014-04-27 EP EP14727380.9A patent/EP2991684B1/en not_active Not-in-force
- 2014-04-27 ES ES14727380.9T patent/ES2691041T3/es active Active
- 2014-04-27 CA CA2910277A patent/CA2910277A1/en not_active Abandoned
- 2014-04-27 WO PCT/US2014/035590 patent/WO2014179184A1/en active Application Filing
- 2014-04-27 US US14/787,444 patent/US20160279252A1/en not_active Abandoned
- 2014-04-28 AR ARP140101748A patent/AR096123A1/es unknown
- 2014-04-28 UY UY0001035545A patent/UY35545A/es not_active Application Discontinuation
-
2016
- 2016-04-27 HK HK16104791.5A patent/HK1217167A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
AR096123A1 (es) | 2015-12-09 |
JP2016519120A (ja) | 2016-06-30 |
EP2991684B1 (en) | 2018-07-11 |
EP2991684A1 (en) | 2016-03-09 |
HK1217167A1 (zh) | 2016-12-30 |
US20160279252A1 (en) | 2016-09-29 |
CN105451774A (zh) | 2016-03-30 |
WO2014179184A1 (en) | 2014-11-06 |
TW201519900A (zh) | 2015-06-01 |
CA2910277A1 (en) | 2014-11-06 |
WO2014179184A8 (en) | 2015-10-29 |
ES2691041T3 (es) | 2018-11-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
109 | Application deemed to be withdrawn |
Effective date: 20211206 |