UY33876A - Derivados de 5-alquinil-piridinas con efecto inhibitorio sobre la actividad de pi3k-alfa - Google Patents
Derivados de 5-alquinil-piridinas con efecto inhibitorio sobre la actividad de pi3k-alfaInfo
- Publication number
- UY33876A UY33876A UY0001033876A UY33876A UY33876A UY 33876 A UY33876 A UY 33876A UY 0001033876 A UY0001033876 A UY 0001033876A UY 33876 A UY33876 A UY 33876A UY 33876 A UY33876 A UY 33876A
- Authority
- UY
- Uruguay
- Prior art keywords
- activity
- piridinas
- alquinil
- pi3k
- alfa
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11152222 | 2011-01-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY33876A true UY33876A (es) | 2012-07-31 |
Family
ID=43736078
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY0001033876A UY33876A (es) | 2011-01-26 | 2012-01-25 | Derivados de 5-alquinil-piridinas con efecto inhibitorio sobre la actividad de pi3k-alfa |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8466162B2 (enExample) |
| EP (1) | EP2668178B1 (enExample) |
| JP (1) | JP2014503570A (enExample) |
| UY (1) | UY33876A (enExample) |
| WO (1) | WO2012101184A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10247481B2 (en) | 2013-01-28 | 2019-04-02 | Carrier Corporation | Multiple tube bank heat exchange unit with manifold assembly |
| US10337799B2 (en) | 2013-11-25 | 2019-07-02 | Carrier Corporation | Dual duty microchannel heat exchanger |
| GR1009604B (el) * | 2018-08-24 | 2019-09-20 | Ιδρυμα Ιατροβιολογικων Ερευνων Της Ακαδημιας Αθηνων | Μεθοδος προετοιμασιας και χρηση αναστολεων της 3-φωσφοινοσιδιτικης κινασης για καρκινικες νοσους |
| CN118530185B (zh) * | 2024-07-25 | 2024-10-22 | 山东仁一生物科技有限责任公司 | 一种制备4-羟基-6-甲基嘧啶的方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7459562B2 (en) * | 2004-04-23 | 2008-12-02 | Bristol-Myers Squibb Company | Monocyclic heterocycles as kinase inhibitors |
| AU2005293607A1 (en) | 2004-10-07 | 2006-04-20 | Boehringer Ingelheim International Gmbh | PI3 kinases |
| US7776869B2 (en) * | 2004-10-18 | 2010-08-17 | Amgen Inc. | Heteroaryl-substituted alkyne compounds and method of use |
| US20080146599A1 (en) * | 2005-02-01 | 2008-06-19 | Astrazeneca Ab | Pyrimidine Compounds Having Tie-2 (Tek) Inhibitory Activity |
| US20080194552A1 (en) | 2005-03-31 | 2008-08-14 | Astrazeneca Ab | Aminopyrimidine Derivatives With Tie2 Inhibiting Activity |
| PE20091617A1 (es) | 2008-03-13 | 2009-11-12 | Boehringer Ingelheim Int | Tiazolil-dihidro-indazoles |
| MX2011000729A (es) * | 2008-07-29 | 2011-03-15 | Boehringer Ingelheim Int | 5-alquinil-pirimidinas. |
| AR076332A1 (es) * | 2009-04-21 | 2011-06-01 | Boehringer Ingelheim Int | Derivados heterociclicos de 5-alquinil-piridinas, composiciones farmaceuticas que los comprenden y uso de los mismos para el tratamiento y/o prevencion del cancer, procesos inflamatorios, autoinmunes, y/o infecciones. |
| UY33198A (es) * | 2010-01-26 | 2011-08-31 | Boehringer Ingelheim Int | 5-alquinil-pirimidinas. |
| US8633183B2 (en) * | 2010-01-26 | 2014-01-21 | Boehringer Ingelheim International Gmbh | 5-alkynyl-pyrimidines |
| TW201245176A (en) * | 2011-01-26 | 2012-11-16 | Boehringer Ingelheim Int | New 5-alkynyl-pyridines |
-
2012
- 2012-01-24 US US13/357,014 patent/US8466162B2/en active Active
- 2012-01-25 WO PCT/EP2012/051165 patent/WO2012101184A1/en not_active Ceased
- 2012-01-25 EP EP12701003.1A patent/EP2668178B1/en active Active
- 2012-01-25 UY UY0001033876A patent/UY33876A/es unknown
- 2012-01-25 JP JP2013550871A patent/JP2014503570A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US8466162B2 (en) | 2013-06-18 |
| EP2668178B1 (en) | 2016-01-20 |
| WO2012101184A1 (en) | 2012-08-02 |
| US20130023533A1 (en) | 2013-01-24 |
| JP2014503570A (ja) | 2014-02-13 |
| EP2668178A1 (en) | 2013-12-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CO2020007218A2 (es) | Nuevas piridopirimidinonas sustituidas con bencilamino y derivados como inhibidores de sos1 | |
| PE20151023A1 (es) | Triazolopirazinas | |
| ECSP14018375A (es) | 6-alquinilo piridinas como miméticos smac | |
| DOP2015000241A (es) | Compuestos de biaril-amida como inhibidores de cinasa | |
| CL2014002873A1 (es) | Compuestos derivados de pirimidin-amina o triazin-amina, inhibidores de adn-pk; composicion farmaceutica; y su uso para el tratamiento del cancer. | |
| NI201300018A (es) | Promotores de apoptosis de n - acilsulfonamidas | |
| UY33890A (es) | Nuevas azaindolilfenil sulfonamidas como inhibidores de serina/ treonina cinasa | |
| CR20150485A (es) | Compuestos triciclicos como inhibidores de la inmunosupresion mediada por el metabolismo del triptofano | |
| MX2019003468A (es) | Derivados de tieno [3,2-d]pirimidina que tienen actividad inhibidora de las cinasas de proteina. | |
| MX386935B (es) | Profármacos de fumaratos y su uso en el tratamiento de diferentes enfermedades. | |
| DOP2015000157A (es) | Lactamas fusionadas de arilo y heteroarilo | |
| ECSP13012499A (es) | Nuevos compuestos | |
| CR20150217A (es) | Inhibidores de histona demetilasas | |
| DOP2013000192A (es) | Compuestos y composiciones como inhibidores de la trk | |
| DOP2012000257A (es) | Derivados del acido 1-amino-2-ciclopropiletilboronico | |
| CL2015001916A1 (es) | Derivados de pirimidona y su uso en el tratamiento, mejora o prevención de una enfermedad viral. | |
| DOP2010000013A (es) | Derivados de pirimidina trisustituida para el tratamiento de enfermedades proliferativas | |
| ECSP13013068A (es) | Halogenoalquil-1,3-oxazinas como inhibidores de la bace1 y/o bace2 | |
| GT201400085A (es) | Profármaco de adrenomedulina basado en polietilenglicol y su uso | |
| CO6491060A2 (es) | Compuestos y composiciones para el tratamiento de enfermedades parasitarias | |
| CR20140144A (es) | Derivados de estra-1,3,5 (10), 16-tetraen-3-carboxamida, procedimientos para su preparación, preparados farmacéuticos que los contienen, así como su uso para la preparación de medicamentos | |
| UY35711A (es) | Bis-amidopiridinas como moduladores de la actividad de iap y sus usos como miméticos de smac | |
| UY35710A (es) | 6-alquinilpiridinas como moduladores de la actividad de iap y sus usos como miméticos de smac | |
| CL2015000039A1 (es) | Derivados estra-1,3,5(10),16-tetraeno-3-sustituidos, preparaciones farmacéuticas que los comprenden y su uso en la preparación de medicamentos para tratar la endometriosis. | |
| PE20170193A1 (es) | Derivados de 6-alquinil-piridina |