UY32515A - NEW ANTI-TARGET DERIVATIVES OF NICOTINAMIDE, ITS PREPARATION AND ITS THERAPEUTIC APPLICATION - Google Patents

NEW ANTI-TARGET DERIVATIVES OF NICOTINAMIDE, ITS PREPARATION AND ITS THERAPEUTIC APPLICATION

Info

Publication number
UY32515A
UY32515A UY0001032515A UY32515A UY32515A UY 32515 A UY32515 A UY 32515A UY 0001032515 A UY0001032515 A UY 0001032515A UY 32515 A UY32515 A UY 32515A UY 32515 A UY32515 A UY 32515A
Authority
UY
Uruguay
Prior art keywords
nicotinamide
preparation
therapeutic application
new anti
target derivatives
Prior art date
Application number
UY0001032515A
Other languages
Spanish (es)
Inventor
Monsif Bouaboula
Romain Combet
Sandrine Hilairet
Samir Jegham
Arigon Jerome
Bernhart Claude
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of UY32515A publication Critical patent/UY32515A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56—Amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La invención se refiere a derivados de nicotinamida que pueden ser utilizados como anticancerososThe invention relates to nicotinamide derivatives that can be used as anti-cancer agents.

UY0001032515A 2009-03-24 2010-03-24 NEW ANTI-TARGET DERIVATIVES OF NICOTINAMIDE, ITS PREPARATION AND ITS THERAPEUTIC APPLICATION UY32515A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0901367A FR2943675A1 (en) 2009-03-24 2009-03-24 ANTICANCER COMPOUNDS, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR0901589A FR2943671B1 (en) 2009-03-24 2009-03-31 ANTICANCER COMPOUNDS, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Publications (1)

Publication Number Publication Date
UY32515A true UY32515A (en) 2010-10-29

Family

ID=41137868

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001032515A UY32515A (en) 2009-03-24 2010-03-24 NEW ANTI-TARGET DERIVATIVES OF NICOTINAMIDE, ITS PREPARATION AND ITS THERAPEUTIC APPLICATION

Country Status (8)

Country Link
US (1) US20120053209A1 (en)
EP (1) EP2411364A1 (en)
JP (1) JP2012521395A (en)
AR (1) AR075922A1 (en)
FR (2) FR2943675A1 (en)
TW (1) TW201038268A (en)
UY (1) UY32515A (en)
WO (1) WO2010109115A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY190351A (en) 2010-09-03 2022-04-15 Genentech Inc Novel compounds and compositions for the inhibition of nampt
MX2013012760A (en) 2011-05-04 2014-03-12 Forma Tm Llc Novel compounds and compositions for the inhibition of nampt.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19756261A1 (en) * 1997-12-17 1999-07-01 Klinge Co Chem Pharm Fab New aryl-substituted pyridylalkane, alkene and alkyarboxylic acid amides
MY153569A (en) * 1998-01-20 2015-02-27 Mitsubishi Tanabe Pharma Corp Inhibitors of ?4 mediated cell adhesion
FR2921657A1 (en) * 2007-09-28 2009-04-03 Sanofi Aventis Sa New nicotinamide derivatives useful for the preparation of a medicament for the treatment or prevention of cancer

Also Published As

Publication number Publication date
JP2012521395A (en) 2012-09-13
FR2943671B1 (en) 2011-05-06
TW201038268A (en) 2010-11-01
FR2943675A1 (en) 2010-10-01
WO2010109115A9 (en) 2011-12-15
AR075922A1 (en) 2011-05-04
US20120053209A1 (en) 2012-03-01
WO2010109115A1 (en) 2010-09-30
FR2943671A1 (en) 2010-10-01
EP2411364A1 (en) 2012-02-01

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20150615