UY29769A1 - PROCESS TO PREPARE SACARINIC ACIDS AND LACTONS - Google Patents

PROCESS TO PREPARE SACARINIC ACIDS AND LACTONS

Info

Publication number
UY29769A1
UY29769A1 UY29769A UY29769A UY29769A1 UY 29769 A1 UY29769 A1 UY 29769A1 UY 29769 A UY29769 A UY 29769A UY 29769 A UY29769 A UY 29769A UY 29769 A1 UY29769 A1 UY 29769A1
Authority
UY
Uruguay
Prior art keywords
sacarinic
lactons
acids
prepare
saccharinic
Prior art date
Application number
UY29769A
Other languages
Spanish (es)
Inventor
David Hotchkiss
George Fleet
Thomas Heinz
Richard Storer
Original Assignee
Novartis Ag
Idenix Pharmaceuticals Inc
Chancellors Master And Scholar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Idenix Pharmaceuticals Inc, Chancellors Master And Scholar filed Critical Novartis Ag
Publication of UY29769A1 publication Critical patent/UY29769A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se divulga un proceso mejorado para preparar un ácido sacarínico o una lactona sacarínica, que utiliza la bien conocida reacción de rearreglo de Amadori. La síntesis utiliza azúcares protegidos o desprotegidos o sus análogos como materiales de partida, y reactivos no utilizados anteriormente para entregar rendimientos aumentados de producto en un tiempo de reacción inferior.An improved process for preparing a saccharinic acid or a saccharinic lactone is disclosed, which uses the well-known Amadori rearrangement reaction. The synthesis uses protected or unprotected sugars or their analogs as starting materials, and reagents not previously used to deliver increased product yields in a lower reaction time.

UY29769A 2005-08-26 2006-08-28 PROCESS TO PREPARE SACARINIC ACIDS AND LACTONS UY29769A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71193405P 2005-08-26 2005-08-26

Publications (1)

Publication Number Publication Date
UY29769A1 true UY29769A1 (en) 2007-02-28

Family

ID=37772543

Family Applications (1)

Application Number Title Priority Date Filing Date
UY29769A UY29769A1 (en) 2005-08-26 2006-08-28 PROCESS TO PREPARE SACARINIC ACIDS AND LACTONS

Country Status (3)

Country Link
AR (1) AR057096A1 (en)
UY (1) UY29769A1 (en)
WO (1) WO2007025304A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY164523A (en) 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
NZ547204A (en) 2000-05-26 2008-01-31 Idenix Cayman Ltd Methods and compositions for treating flaviviruses and pestiviruses
HUE033832T2 (en) 2002-11-15 2018-01-29 Idenix Pharmaceuticals Llc 2'-methyl nucleosides in combination with interferon and flaviviridae mutation
JP5342887B2 (en) * 2009-01-29 2013-11-13 花王株式会社 Method for producing α-aminoketone compound
US20150126752A1 (en) 2012-06-13 2015-05-07 Bristol-Myers Squibb Company Process for the preparation of 2-c-methyl-d-ribonic-gamma-lactone
CN104693157A (en) * 2015-02-15 2015-06-10 上海应用技术学院 Preparation method of 2-C-methyl-D-ribotide-1,4-lactone
CN104693158B (en) * 2015-02-15 2017-03-29 上海应用技术学院 A kind of method for preparing 2 C methyl D ribonic acids, 1,4 lactone

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITFI20030033A1 (en) * 2003-02-10 2004-08-11 Inalco Spa PROCESS FOR THE PREPARATION OF RIBOFURANOSIDIC DERIVATIVES

Also Published As

Publication number Publication date
WO2007025304A2 (en) 2007-03-01
AR057096A1 (en) 2007-11-14
WO2007025304A3 (en) 2007-05-31

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Legal Events

Date Code Title Description
104 Application deemed to be withdrawn (no substantive examination fee paid)

Effective date: 20131122