UY29124A1 - QUINOLINE COMPOUNDS - Google Patents

QUINOLINE COMPOUNDS

Info

Publication number
UY29124A1
UY29124A1 UY29124A UY29124A UY29124A1 UY 29124 A1 UY29124 A1 UY 29124A1 UY 29124 A UY29124 A UY 29124A UY 29124 A UY29124 A UY 29124A UY 29124 A1 UY29124 A1 UY 29124A1
Authority
UY
Uruguay
Prior art keywords
compounds
levels
certain
triglycerides
quinoline compounds
Prior art date
Application number
UY29124A
Other languages
Spanish (es)
Inventor
Roger Benjamin Ruggeri
David Austen Perry
Mary Theresa Didiuk
Ryan Michael Kelley
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of UY29124A1 publication Critical patent/UY29124A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

Compuestos de quinolina, composiciones farmacéuticas que contienen tales compuestos y el uso de tales compuestos para elevar ciertos niveles de lípidos en plasma, incluyendo el colessterol asociado a lipoproteínas de alta densidad y para reducir otros ciertos niveles de lípidos en plasma, tales como el colesterol LDL y los triglicéridos y, por consiguiente, para tratar enfermedades que están exacerbadas por bajos niveles de colesterol HDL y/o altos niveles de colesterol LDL y triglicéridos, tales como la aterosclerosis y enfermedades cardiovasculares en ciertos mamíferos incluyendo los seres humanos.Quinoline compounds, pharmaceutical compositions containing such compounds and the use of such compounds to raise certain levels of plasma lipids, including colessterol associated with high density lipoproteins and to reduce other certain levels of plasma lipids, such as LDL cholesterol and triglycerides and, therefore, to treat diseases that are exacerbated by low levels of HDL cholesterol and / or high levels of LDL cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in certain mammals including humans.

UY29124A 2004-09-23 2005-09-20 QUINOLINE COMPOUNDS UY29124A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61286304P 2004-09-23 2004-09-23

Publications (1)

Publication Number Publication Date
UY29124A1 true UY29124A1 (en) 2006-04-28

Family

ID=35511128

Family Applications (1)

Application Number Title Priority Date Filing Date
UY29124A UY29124A1 (en) 2004-09-23 2005-09-20 QUINOLINE COMPOUNDS

Country Status (8)

Country Link
US (1) US20070149567A1 (en)
AR (1) AR054085A1 (en)
GT (1) GT200500264A (en)
NL (1) NL1030012C2 (en)
PE (1) PE20060819A1 (en)
TW (1) TW200616964A (en)
UY (1) UY29124A1 (en)
WO (1) WO2006033004A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003269327A1 (en) * 2002-10-21 2004-05-04 Warner-Lambert Company Llc Tetrahydroquinoline derivatives as crth2 antagonists
PT1740591E (en) 2004-04-02 2009-09-24 Osi Pharm Inc 6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitors
WO2007107843A1 (en) * 2006-03-22 2007-09-27 Pfizer Products Inc. Methods of treatment with cetp inhibitors
JP2012524119A (en) 2009-04-20 2012-10-11 オーエスアイ・ファーマシューティカルズ,エルエルシー Preparation of C-pyrazine-methylamine
CA2809958A1 (en) 2010-08-31 2012-03-08 Snu R & Db Foundation Use of the fetal reprogramming of a ppar ? agonist

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GT199900147A (en) * 1998-09-17 1999-09-06 1, 2, 3, 4- TETRAHIDROQUINOLINAS 2-SUBSTITUTED 4-AMINO SUBSTITUTED.
CO5271716A1 (en) * 1999-11-30 2003-04-30 Pfizer Prod Inc CRYSTALS OF 4- CARBOXAMINE 1,2,3,4-TETRAHYDROQUINOLINE 2- REPLACED
MXPA05010456A (en) * 2003-03-28 2006-03-21 Pfizer Prod Inc 1,2,4-substituerte 1,2,3,4-tetrahydro-and 1,2 dihydro-quinoline and 1,2,3,4-tetrahydro-quinoxaline derivatives as cetp inhibitors for the treatment of atherosclerosis and obesity.
MXPA06003499A (en) * 2003-09-30 2006-06-08 Pfizer Prod Inc Cetp inhibitors and metabolites thereof.

Also Published As

Publication number Publication date
AR054085A1 (en) 2007-06-06
PE20060819A1 (en) 2006-09-02
NL1030012C2 (en) 2006-11-21
US20070149567A1 (en) 2007-06-28
GT200500264A (en) 2006-06-02
TW200616964A (en) 2006-06-01
NL1030012A1 (en) 2006-03-27
WO2006033004A1 (en) 2006-03-30

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20160530