ECSP088730A - DIBENCILAMINE DERIVATIVES AS CETP INHIBITORS - Google Patents

DIBENCILAMINE DERIVATIVES AS CETP INHIBITORS

Info

Publication number
ECSP088730A
ECSP088730A ECSP088730A ECSP088730A EC SP088730 A ECSP088730 A EC SP088730A EC SP088730 A ECSP088730 A EC SP088730A EC SP088730 A ECSP088730 A EC SP088730A
Authority
EC
Ecuador
Prior art keywords
cholesterol
derivatives
compounds
dibencilamine
cetp inhibitors
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Bruce Allen Lefker
George Chang
David Austen Perry
Ravi Shanker Garigipati
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of ECSP088730A publication Critical patent/ECSP088730A/en

Links

Abstract

RESUMENCompuestos de dibencilamina y derivados, composiciones farmacéuticas que contienen estos compuestos y el uso de estos compuestos para elevar los niveles plasmáticos de ciertos lípidos, incluyendo el colesterol asociado a lipoproteínas de alta densidad y para reducir los niveles plasmáticos de otros lípidos, tales como el colesterol LDL y los triglicéridos y, por consiguiente, para tratar enfermedades que se exacerban por bajos niveles de colesterol-HDL y/o altos niveles de colesterol-LDL y triglicéridos, tales como aterosclerosis y enfermedades cardiovasculares en algunos mamíferos, incluyendo seres humanos.SUMMARY Dibenzylamine compounds and derivatives, pharmaceutical compositions containing these compounds and the use of these compounds to raise plasma levels of certain lipids, including cholesterol associated with high-density lipoproteins and to reduce plasma levels of other lipids, such as cholesterol LDL and triglycerides and, therefore, to treat diseases that are exacerbated by low levels of HDL-cholesterol and / or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.

ECSP088730 2006-03-10 2008-09-10 DIBENCILAMINE DERIVATIVES AS CETP INHIBITORS ECSP088730A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78148806P 2006-03-10 2006-03-10

Publications (1)

Publication Number Publication Date
ECSP088730A true ECSP088730A (en) 2008-10-31

Family

ID=40459931

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP088730 ECSP088730A (en) 2006-03-10 2008-09-10 DIBENCILAMINE DERIVATIVES AS CETP INHIBITORS

Country Status (3)

Country Link
CN (1) CN101437803A (en)
EC (1) ECSP088730A (en)
ZA (1) ZA200807106B (en)

Also Published As

Publication number Publication date
CN101437803A (en) 2009-05-20
ZA200807106B (en) 2009-11-25

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