UY29112A1 - DERIVATIVES OF CONDENSED PIRAZOL, ITS PREPARATION AND ITS THERAPEUTIC APPLICATION - Google Patents

DERIVATIVES OF CONDENSED PIRAZOL, ITS PREPARATION AND ITS THERAPEUTIC APPLICATION

Info

Publication number
UY29112A1
UY29112A1 UY29112A UY29112A UY29112A1 UY 29112 A1 UY29112 A1 UY 29112A1 UY 29112 A UY29112 A UY 29112A UY 29112 A UY29112 A UY 29112A UY 29112 A1 UY29112 A1 UY 29112A1
Authority
UY
Uruguay
Prior art keywords
preparation
pirazol
condensed
derivatives
therapeutic application
Prior art date
Application number
UY29112A
Other languages
Spanish (es)
Inventor
Francis Barth
Christian Congy
Murielle Rinaldi-Carmona
Vernhet Claude
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of UY29112A1 publication Critical patent/UY29112A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención tiene por objeto compuestos que responden a la fórmula (1)¨: en la que: A,W,R1,R2,R3,B R4 son como fueron definidos en la Memoria Descriptiva y Reivindicaciones, procedimiento de preparación y aplicación en terapéutica.The present invention aims at compounds that respond to formula (1) ¨: wherein: A, W, R1, R2, R3, B R4 are as defined in the specification and claims, preparation and application procedure in therapy.

UY29112A 2004-09-13 2005-09-09 DERIVATIVES OF CONDENSED PIRAZOL, ITS PREPARATION AND ITS THERAPEUTIC APPLICATION UY29112A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0409712A FR2875230A1 (en) 2004-09-13 2004-09-13 CONDENSED PYRAZOLE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF

Publications (1)

Publication Number Publication Date
UY29112A1 true UY29112A1 (en) 2006-04-28

Family

ID=34954413

Family Applications (1)

Application Number Title Priority Date Filing Date
UY29112A UY29112A1 (en) 2004-09-13 2005-09-09 DERIVATIVES OF CONDENSED PIRAZOL, ITS PREPARATION AND ITS THERAPEUTIC APPLICATION

Country Status (6)

Country Link
AR (1) AR051288A1 (en)
FR (1) FR2875230A1 (en)
PE (1) PE20060627A1 (en)
TW (1) TW200621786A (en)
UY (1) UY29112A1 (en)
WO (1) WO2006030124A1 (en)

Families Citing this family (34)

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US7923465B2 (en) 2005-06-02 2011-04-12 Glenmark Pharmaceuticals S.A. Cannabinoid receptor ligands, pharmaceutical compositions containing them, and process for their preparation
JP2008545739A (en) * 2005-06-02 2008-12-18 グレンマーク・ファーマシューティカルズ・エスエー Novel cannabinoid receptor ligands, pharmaceutical compositions containing them, and methods for their preparation
WO2007001939A1 (en) * 2005-06-27 2007-01-04 Janssen Pharmaceutica N.V. Tetrahydro-pyranopyrazole compounds displaying cannabinoid modulating activities
BRPI0616404A2 (en) * 2005-09-23 2011-06-21 Janssen Pharmaceutica Nv substituted 3-starch-tetrahydro-indazolyl cannabinoid modulators and use thereof
AU2006302659A1 (en) * 2005-09-23 2007-04-19 Janssen Pharmaceutica, N.V. Hexahydro cyclooctyl pyrazole cannabinoid modulators
BRPI0616402A2 (en) * 2005-09-23 2011-06-21 Janssen Pharmaceutica Nv cannabinoid modulators of hexahydro-cyclopeptazole
US8378096B2 (en) 2005-09-23 2013-02-19 Janssen Pharmaceutica N.V. Hexahydro-cycloheptapyrazole cannabinoid modulators
US7825151B2 (en) 2005-09-23 2010-11-02 Janssen Pharmaceutica Nv Hexahydro-cyclooctyl pyrazole cannabinoid modulators
WO2007035945A1 (en) 2005-09-23 2007-03-29 Janssen Pharmaceutica, N.V. Tetrahydro-cyclopentyl pyrazole cannabinoid modulators
US8378117B2 (en) * 2005-09-23 2013-02-19 Janssen Pharmaceutica N.V. Hexahydro-cycloheptapyrazole cannabinoid modulators
WO2007095513A1 (en) * 2006-02-14 2007-08-23 Janssen Pharmaceutica, Nv Tetrahydr0-2h-indaz0le derivatives for use as cannabinoid modulators
US20070254911A1 (en) * 2006-03-27 2007-11-01 Mingde Xia Tetrahydro-Pyrazolo[3,4-c]Pyridine Cannabinoid Modulators
MX2009010164A (en) * 2007-03-21 2009-10-12 Janssen Pharmaceutica Nv Method for treating cb2 receptor mediated pain.
KR20090120499A (en) * 2007-03-21 2009-11-24 얀센 파마슈티카 엔.브이. Treatment of CB2 Receptor-mediated Pain
JPWO2009119088A1 (en) * 2008-03-25 2011-07-21 武田薬品工業株式会社 Heterocyclic compounds
CA2749884C (en) * 2009-01-28 2018-01-23 Cara Therapeutics, Inc. Bicyclic pyrazolo-heterocycles
KR20180115807A (en) * 2009-08-28 2018-10-23 아레나 파마슈티칼스, 인크. Cannabinoid receptor modulators
MX2012006326A (en) 2009-12-04 2012-10-09 Sunovion Pharmaceuticals Inc Multicyclic compounds and methods of use thereof.
US20140206649A1 (en) * 2011-02-25 2014-07-24 Jayant Thatte Cannabinoid receptor modulators
DK3395812T3 (en) * 2011-02-25 2022-11-28 Arena Pharm Inc Crystalline forms and methods for the preparation of fused azacycles (cannabinoid receptor modulators)
US9597340B2 (en) 2011-02-25 2017-03-21 Arena Pharmaceuticals, Inc. Cannabinoid receptor modulators
WO2012116278A1 (en) * 2011-02-25 2012-08-30 Arena Pharmaceuticals, Inc. Cannabinoid receptor modulators
US20150141372A1 (en) * 2012-05-11 2015-05-21 Bayer Pharma Aktiengesellschaft Substituted cycloalkenopyrazoles as bub1 inhibitors for the treatment of cancer
EP3402780A1 (en) 2016-01-14 2018-11-21 Beth Israel Deaconess Medical Center, Inc. Mast-cell modulators and uses thereof
UA125519C2 (en) 2016-07-29 2022-04-13 Суновіон Фармасьютікалз Інк. COMPOUNDS AND COMPOSITIONS AND THEIR APPLICATIONS
MA45795A (en) 2016-07-29 2019-06-05 Sunovion Pharmaceuticals Inc COMPOUNDS AND COMPOSITIONS, AND ASSOCIATED USES
CN110678205B (en) 2017-02-16 2023-05-23 桑诺维恩药品公司 Methods of treating schizophrenia
EP3621619B1 (en) 2017-05-08 2023-06-28 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of visceral pain
EA202090414A1 (en) 2017-08-02 2020-05-28 Суновион Фармасьютикалз Инк. COMPOUNDS AND THEIR APPLICATION
AU2019222491B2 (en) 2018-02-16 2023-01-12 Sunovion Pharmaceuticals Inc. Salts, crystal forms, and production methods thereof
CA3130849A1 (en) 2019-03-14 2020-09-17 Sunovion Pharmaceuticals Inc. Salts of a isochromanyl compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof
TWI768464B (en) * 2019-09-12 2022-06-21 大陸商四川海思科製藥有限公司 Tricyclic pyrazole derivatives and their preparation
CN114391011A (en) * 2019-09-12 2022-04-22 四川海思科制药有限公司 Hexahydro-benzo-pyrazole derivative and preparation thereof
MX2022012833A (en) 2020-04-14 2022-11-07 Sunovion Pharmaceuticals Inc (s)-(4,5-dihydro-7h-thieno[2,3-c]pyran-7-yl)-n-methylmethanamine for treating neurological and psychiatric disorders.

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Publication number Priority date Publication date Assignee Title
FR2742148B1 (en) * 1995-12-08 1999-10-22 Sanofi Sa NOVEL PYRAZOLE-3-CARBOXAMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2800375B1 (en) * 1999-11-03 2004-07-23 Sanofi Synthelabo TRICYCLIC DERIVATIVES OF PYRAZOLECARBOXYLIC ACID, THEIR PREPARATION, THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
AU2001234958A1 (en) * 2000-02-11 2001-08-20 Bristol-Myers Squibb Company Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators for treating respiratory and non-respiratory diseases
US7666867B2 (en) * 2001-10-26 2010-02-23 University Of Connecticut Heteroindanes: a new class of potent cannabimimetic ligands
EP1735286B1 (en) * 2004-03-24 2012-01-04 Janssen Pharmaceutica NV Tetrahydro-indazole cannabinoid modulators

Also Published As

Publication number Publication date
AR051288A1 (en) 2007-01-03
WO2006030124A1 (en) 2006-03-23
FR2875230A1 (en) 2006-03-17
PE20060627A1 (en) 2006-08-15
TW200621786A (en) 2006-07-01

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20160530