UY29112A1 - DERIVATIVES OF CONDENSED PIRAZOL, ITS PREPARATION AND ITS THERAPEUTIC APPLICATION - Google Patents

DERIVATIVES OF CONDENSED PIRAZOL, ITS PREPARATION AND ITS THERAPEUTIC APPLICATION

Info

Publication number
UY29112A1
UY29112A1 UY29112A UY29112A UY29112A1 UY 29112 A1 UY29112 A1 UY 29112A1 UY 29112 A UY29112 A UY 29112A UY 29112 A UY29112 A UY 29112A UY 29112 A1 UY29112 A1 UY 29112A1
Authority
UY
Uruguay
Prior art keywords
preparation
pirazol
condensed
derivatives
therapeutic application
Prior art date
Application number
UY29112A
Other languages
Spanish (es)
Inventor
Francis Barth
Christian Congy
Murielle Rinaldi-Carmona
Vernhet Claude
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of UY29112A1 publication Critical patent/UY29112A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención tiene por objeto compuestos que responden a la fórmula (1)¨: en la que: A,W,R1,R2,R3,B R4 son como fueron definidos en la Memoria Descriptiva y Reivindicaciones, procedimiento de preparación y aplicación en terapéutica.The present invention aims at compounds that respond to formula (1) ¨: wherein: A, W, R1, R2, R3, B R4 are as defined in the specification and claims, preparation and application procedure in therapy.

UY29112A 2004-09-13 2005-09-09 DERIVATIVES OF CONDENSED PIRAZOL, ITS PREPARATION AND ITS THERAPEUTIC APPLICATION UY29112A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0409712A FR2875230A1 (en) 2004-09-13 2004-09-13 CONDENSED PYRAZOLE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF

Publications (1)

Publication Number Publication Date
UY29112A1 true UY29112A1 (en) 2006-04-28

Family

ID=34954413

Family Applications (1)

Application Number Title Priority Date Filing Date
UY29112A UY29112A1 (en) 2004-09-13 2005-09-09 DERIVATIVES OF CONDENSED PIRAZOL, ITS PREPARATION AND ITS THERAPEUTIC APPLICATION

Country Status (6)

Country Link
AR (1) AR051288A1 (en)
FR (1) FR2875230A1 (en)
PE (1) PE20060627A1 (en)
TW (1) TW200621786A (en)
UY (1) UY29112A1 (en)
WO (1) WO2006030124A1 (en)

Families Citing this family (33)

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US7923465B2 (en) 2005-06-02 2011-04-12 Glenmark Pharmaceuticals S.A. Cannabinoid receptor ligands, pharmaceutical compositions containing them, and process for their preparation
WO2006129178A1 (en) * 2005-06-02 2006-12-07 Glenmark Pharmaceuticals S.A. Novel cannabinoid receptor ligands, pharmaceutical compositions containing them, and process for their preparation
WO2007001939A1 (en) * 2005-06-27 2007-01-04 Janssen Pharmaceutica N.V. Tetrahydro-pyranopyrazole compounds displaying cannabinoid modulating activities
BRPI0616263A2 (en) * 2005-09-23 2011-06-14 Janssen Pharmaceutica Nv cannabinoid modulators of the tetrahydro-cyclopentyl pyrazole type
PL1937259T3 (en) * 2005-09-23 2012-04-30 Janssen Pharmaceutica Nv Hexahydro-cycloheptapyrazole cannabinoid modulators
US7825151B2 (en) 2005-09-23 2010-11-02 Janssen Pharmaceutica Nv Hexahydro-cyclooctyl pyrazole cannabinoid modulators
ATE458480T1 (en) 2005-09-23 2010-03-15 Janssen Pharmaceutica Nv HEXAHYDRO-CYCLOOCTYL-PYRAZOLE CANNABINOID MODULATORS
WO2007038045A1 (en) * 2005-09-23 2007-04-05 Janssen Pharmaceutica, N.V. Tetrahydro-indazolyl cannabinoid modulators
US8378117B2 (en) 2005-09-23 2013-02-19 Janssen Pharmaceutica N.V. Hexahydro-cycloheptapyrazole cannabinoid modulators
US8378096B2 (en) 2005-09-23 2013-02-19 Janssen Pharmaceutica N.V. Hexahydro-cycloheptapyrazole cannabinoid modulators
WO2007095513A1 (en) * 2006-02-14 2007-08-23 Janssen Pharmaceutica, Nv Tetrahydr0-2h-indaz0le derivatives for use as cannabinoid modulators
US20070254911A1 (en) * 2006-03-27 2007-11-01 Mingde Xia Tetrahydro-Pyrazolo[3,4-c]Pyridine Cannabinoid Modulators
WO2008115671A1 (en) * 2007-03-21 2008-09-25 Janssen Pharmaceutica N.V. Method for treating cb2 receptor mediated pain
CN101677555A (en) * 2007-03-21 2010-03-24 詹森药业有限公司 Method for treating cb2 receptor mediated pain
US20110118236A1 (en) * 2008-03-25 2011-05-19 Michiyo Mochizuki Heterocyclic compound
CA2749884C (en) * 2009-01-28 2018-01-23 Cara Therapeutics, Inc. Bicyclic pyrazolo-heterocycles
SG10201901293RA (en) * 2009-08-28 2019-03-28 Arena Pharm Inc Cannabinoid receptor modulators
AU2010325925B2 (en) 2009-12-04 2016-02-25 Pgi Drug Discovery Llc. Multicyclic compounds and methods of use thereof
WO2012116278A1 (en) * 2011-02-25 2012-08-30 Arena Pharmaceuticals, Inc. Cannabinoid receptor modulators
KR102036932B1 (en) * 2011-02-25 2019-10-25 아레나 파마슈티칼스, 인크. Crystalline forms and processes for the preparation of condensed azacycles (cannabinoid receptor modulators)
US9597340B2 (en) 2011-02-25 2017-03-21 Arena Pharmaceuticals, Inc. Cannabinoid receptor modulators
MX346644B (en) * 2011-02-25 2017-03-14 Arena Pharm Inc Cannabinoid receptor modulators.
ES2620316T3 (en) * 2012-05-11 2017-06-28 Bayer Pharma Aktiengesellschaft Cycloalkenopyrazoles substituted as BUB1 inhibitors for cancer treatment
CA3010615C (en) 2016-01-14 2024-02-20 Beth Israel Deaconess Medical Center, Inc. Mast-cell modulators and uses thereof
MA45857A (en) 2016-07-29 2021-05-19 Sunovion Pharmaceuticals Inc COMPOUNDS AND COMPOSITIONS, AND ASSOCIATED USES
JP2019523279A (en) 2016-07-29 2019-08-22 サノビオン ファーマシューティカルズ インクＳｕｎｏｖｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． Compounds and compositions and their use
AU2018220509B2 (en) 2017-02-16 2022-04-28 Sunovion Pharmaceuticials Inc. Methods of treating schizophrenia
CA3070993A1 (en) 2017-08-02 2019-02-07 Sunovion Pharmaceuticals Inc. Isochroman compounds and uses thereof
KR20200122345A (en) 2018-02-16 2020-10-27 선오비온 파마슈티컬스 인코포레이티드 Salts, crystalline forms and methods for their preparation
MX2021010880A (en) 2019-03-14 2022-01-18 Sunovion Pharmaceuticals Inc Salts of a isochromanyl compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof.
WO2021047581A1 (en) * 2019-09-12 2021-03-18 四川海思科制药有限公司 Hexahydrobenzopyrazole derivative and preparation therefof
CN114391010A (en) * 2019-09-12 2022-04-22 四川海思科制药有限公司 Tricyclic pyrazole derivative and preparation thereof
CA3180115A1 (en) 2020-04-14 2021-10-21 Sunovion Pharmaceuticals Inc. (s)-(4,5-dihydro-7h-thieno[2,3-c]pyran-7-yl)-n-methylmethanamine for treating neurological and psychiatric disorders

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2742148B1 (en) * 1995-12-08 1999-10-22 Sanofi Sa NOVEL PYRAZOLE-3-CARBOXAMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2800375B1 (en) * 1999-11-03 2004-07-23 Sanofi Synthelabo TRICYCLIC DERIVATIVES OF PYRAZOLECARBOXYLIC ACID, THEIR PREPARATION, THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
CA2399791A1 (en) * 2000-02-11 2001-08-16 Bristol-Myers Squibb Company Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators in treating respiratory and non-respiratory diseases
JP2005510492A (en) * 2001-10-26 2005-04-21 ユニバーシティ オブ コネチカット A new class of potent cannabis mimetic ligands
TW200602324A (en) * 2004-03-24 2006-01-16 Janssen Pharmaceutica Nv Tetrahydro-indazole cannabinoid modulators cross reference to related applications

Also Published As

Publication number Publication date
WO2006030124A1 (en) 2006-03-23
FR2875230A1 (en) 2006-03-17
AR051288A1 (en) 2007-01-03
PE20060627A1 (en) 2006-08-15
TW200621786A (en) 2006-07-01

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Legal Events

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Effective date: 20160530