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Application filed by Hoffmann La RochefiledCriticalHoffmann La Roche
Priority to UY27182ApriorityCriticalpatent/UY27182A1/en
Publication of UY27182A1publicationCriticalpatent/UY27182A1/en
Medicines That Contain Protein Lipid Enzymes And Other Medicines
(AREA)
Peptides Or Proteins
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Medicinal Preparation
(AREA)
Abstract
Un conjugado que comprende un fragmento N-terminal del factor de crecimiento de los hepatocitos (hgf/sf) que consiste en el dominio horquilla y las cuatro regiones "kringle" de la cadena alfa, y un grupo polietilenglicol, que tiene un peso molecular en conjunto desde aproximadamente 20 hasta 40 kDa, tiene propiedades perfeccionadas y es un agente terapéutico de utilidad para el tratamiento de tumores.A conjugate comprising an N-terminal fragment of hepatocyte growth factor (hgf / sf) consisting of the hairpin domain and the four "kringle" regions of the alpha chain, and a polyethylene glycol group, which has a molecular weight in set from approximately 20 to 40 kDa, it has improved properties and is a therapeutic agent useful for the treatment of tumors.
UY27182A2002-02-222002-02-22
PEG CONJUGATES OF HGF-NK4
UY27182A1
(en)