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Application filed by Boehringer Ingelheim Pharma, Amp, Co KgfiledCriticalBoehringer Ingelheim Pharma
Priority to UY26214ApriorityCriticalpatent/UY26214A1/en
Publication of UY26214A1publicationCriticalpatent/UY26214A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Nitrogen Condensed Heterocyclic Rings
(AREA)
Abstract
La presente invención se refiere a heterociclos bicíclicos de la fórmula general (I) en la que Ra a Rc, A a E y X están definidos como en la reivindicación 1, a sus tautómeros, sus estereoisómeros y sus sales, en particular sus sales fisiológicamente compatibles con ácidos o bases inorgánicos u orgánicos, que presentan valiosas propiedades farmacológicas, en particular un efecto inhibidor sobre la transducción de senales inducidas por tirosinaquinasas, a su empleo para el tratamiento de enfermedades, en particular de enfermedades tumorales, de enfermedades de los pulmones y de las vías respiratorias, y a su preparación.The present invention relates to bicyclic heterocycles of the general formula (I) in which Ra to Rc, A to E and X are defined as in claim 1, to their tautomers, their stereoisomers and their salts, in particular their physiologically compatible with inorganic or organic acids or bases, which have valuable pharmacological properties, in particular an inhibitory effect on tyrosine kinase-induced signal transduction, for use in the treatment of diseases, in particular tumor diseases, diseases of the lungs and of the respiratory tract, and its preparation.
UY26214A2000-06-212000-06-21
BICYCLE HETERO CYCLES, MEDICINES CONTAINING THESE COMPOUNDS, THEIR USE AND PROCEDURES FOR THEIR PREPARATION
UY26214A1
(en)
PIRIMIDO [5,4-D] PYRIMIDINES, THEIR PHYSIOLOGICALLY COMPATIBLE SALTS, A PROCEDURE FOR THEIR PREPARATION, THEIR USE FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS, AND THE PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM