UST993005I4 - Preparation of aromatic fluoro compounds - Google Patents

Preparation of aromatic fluoro compounds Download PDF

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Publication number
UST993005I4
UST993005I4 US06/022,597 US2259779A UST993005I4 US T993005 I4 UST993005 I4 US T993005I4 US 2259779 A US2259779 A US 2259779A US T993005 I4 UST993005 I4 US T993005I4
Authority
US
United States
Prior art keywords
diphenylmethane
yield
preparation
difluorobenzophenone
difluoro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
US06/022,597
Inventor
Philip A. Staniland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Application granted granted Critical
Publication of UST993005I4 publication Critical patent/UST993005I4/en
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/28Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of CHx-moieties

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The present invention relates to a process for the preparation of 4,4'-difluorobenzophenone. 4,4-difluorobenzophenone may be prepared by diazotization of 4,4'-diamino-diphenylmethane in anhydrous or concentrated aqueous hydrogen fluoride, decomposition of the diazonium fluoride thus produced to yield 4,4'-difluoro-diphenylmethane and oxidation of 4,4'-difluoro-diphenylmethane to yield 4,4'-difluorobenzophonone.
Thus, according to the present invention, there is provided a process for the preparation of 4,4'-difluorobenzophenone which comprises the following steps:
(1) diazotization of 4,4'-diamino-diphenylmethane in anhydrous or concentrated aqueous hydrogen fluoride to yield a solution of a corresponding diazonium fluoride; and
(2) (i) thermally decomposing the diazonium fluoride in the solution thus produced to yield 4,4'-difluoro-diphenylmethane and (ii) subsequently oxidizing the 4,4'-difluoro-diphenylmethane to yield 4,4'-difluorobenzophenone.
US06/022,597 1978-03-31 1979-03-19 Preparation of aromatic fluoro compounds Pending UST993005I4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB1266478 1978-03-31
GB12664/78 1978-03-31
GB7832842 1978-08-10
GB32842/78 1978-08-10

Publications (1)

Publication Number Publication Date
UST993005I4 true UST993005I4 (en) 1980-04-01

Family

ID=26249181

Family Applications (1)

Application Number Title Priority Date Filing Date
US06/022,597 Pending UST993005I4 (en) 1978-03-31 1979-03-19 Preparation of aromatic fluoro compounds

Country Status (1)

Country Link
US (1) UST993005I4 (en)

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