US7816657B2 - Particle therapy system - Google Patents

Particle therapy system Download PDF

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Publication number
US7816657B2
US7816657B2 US12/110,889 US11088908A US7816657B2 US 7816657 B2 US7816657 B2 US 7816657B2 US 11088908 A US11088908 A US 11088908A US 7816657 B2 US7816657 B2 US 7816657B2
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Prior art keywords
beam
system
particle
energy
selection system
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US12/110,889
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US20080290299A1 (en
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Thomas Hansmann
Eike Rietzel
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Siemens Healthcare GmbH
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Siemens AG
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Priority to DE200710020599 priority Critical patent/DE102007020599A1/en
Priority to DE102007020599 priority
Priority to DEDE102007020599.8 priority
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Assigned to SIEMENS AKTIENGESELLSCHAFT reassignment SIEMENS AKTIENGESELLSCHAFT ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: HANSMANN, THOMAS, RIETZEL, EIKE
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1077Beam delivery systems
    • A61N5/1079Sharing a beam by multiple treatment stations
    • GPHYSICS
    • G21NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21KTECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES
    • G21K1/00Arrangements for handling particles or ionising radiation, e.g. focusing or moderating
    • G21K1/10Scattering devices; Absorbing devices; Ionising radiation filters
    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05HPLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H7/00Details of devices of the types covered by groups H05H9/00, H05H11/00, H05H13/00
    • H05H7/12Arrangements for varying final energy of beam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1085X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
    • A61N2005/1087Ions; Protons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092Details
    • A61N2005/1095Elements inserted into the radiation path within the system, e.g. filters or wedges

Abstract

A particle therapy system is provided. The particle therapy system includes at least two acceleration units, with each of which acceleration units particles can be accelerated to at least an energy necessary for the irradiation; and a common energy selection system, connected downstream of the at least two acceleration units, with which system the energy of particles that have been accelerated by one of the acceleration units can be reduced.

Description

This patent document claims the benefit of DE 10 2007 020 599.8, filed May 2, 2007, which is hereby incorporated by reference.

BACKGROUND

The present embodiments relate to particle therapy.

Particle therapy may be used for radiation therapy. Particle therapy includes irradiating a tissue to be treated with high-energy particle radiation. Protons or carbon ions are generally used for irradiation, but other types of particles, such as pions or helium ions, may be used.

Particles interact with the tissue differently than gamma rays. As long as the particles have high energy (e.g., on the order of magnitude of >50 MeV/u), the particle interaction with the tissue is relatively low with respect to gamma rays. The interaction does not increase until after the particles have lost energy when passing through tissue. The interaction with the tissue takes place predominantly along a distance that is on the order of magnitude of a few millimeters and decreases to zero. The particle profile generated in the process is called the Bragg peak. The particle interaction makes it possible to aim the energy of the particle beam in a targeted way at a tumor, for instance, in the interior of the body while sparing the surrounding tissue and organs. The penetration depth of the particles and the site of the maximum effect are determined by the energy of the particle beam. During irradiation, energy levels for protons are generally in the range from 48 MeV/u to 250 MeV/u, and with carbon ions in the range from 85 MeV/u to 430 MeV/u.

A cyclotron is used to accelerate particles to high energy. Electrically charged particles are generated by an ion source and accelerated in the cyclotron, with strong electromagnetic fields in a spiral path, to a target energy level. The particles are expelled from the cyclotron using the fastest spiral path at the periphery of the cyclotron. After the particle beam leaves the cyclotron, the energy level is adjusted, so that the energy of the particle beam is adapted to the desired penetration depth. A selection system is connected downstream of the cyclotron. The selection system may be used to adjust the energy level. A beam transporting system is used to carry the particle beam to the desired treatment place. Further adjustment of the energy level of the particle beam—may occur downstream of the energy selection system.

Cyclotron-based particle therapy systems may accelerate two different types of particles and use the two different types of particles for irradiation. For instance, each type of particle is accelerated in its own cyclotron adapted to that type of particle.

SUMMARY AND DESCRIPTION

The present embodiments may obviate one or more of the drawbacks or limitations inherent in the related art. For example, in one embodiment, a particle therapy system includes at least two acceleration units that are constructed and operated in a simple, economical way.

In one embodiment, the particle therapy system includes at least two acceleration units. The acceleration units may accelerate particles to at least an irradiation energy level. A common energy selection system, which is connected to the acceleration units, may be used to reduce the energy of particles that have been accelerated by one of the acceleration units. The particle therapy system may be used for treatment of tumors.

One common energy selection system may be used by a plurality of acceleration units, which are parallel to one another. The beam course of the various particle beams, which emerge from the acceleration units, may be united (brought together), for example, upstream of the energy selection system. As an alternative, two parallel beam courses may be combined with a single energy selection system, for example, by positioning the energy selection system in the particular beam course where the parallel beam courses are combined.

The common energy selection system may include shielding from radiation exposure. An energy selection system may slow down the particle beams by interaction with material. Radiation exposure in the vicinity of an energy selection system is comparatively high. A single common energy selection system may include a single shielding provision from the radiation exposure. Radiation protection requirements may be reduced compared to particle therapy systems with multiple acceleration units with multiple respective downstream energy selection systems.

The at least two acceleration units may accelerate different types of particles. Each of the acceleration units may accelerate its own type of particle.

Each type of particle may include its own acceleration unit. The different types of particles generally differ in terms of mass, charge, and/or mass-charge ratio. The acceleration units may be adapted to the type of particle.

The common energy selection system may be adjoined by a beam transporting system. The beam transporting system may guide the particles to one or more treatment rooms.

In one embodiment, the acceleration units may be embodied as a cyclotron-based acceleration system. The cyclotron-based acceleration system may include a common downstream energy selection system. The particle beam emerging from a cyclotron has a fixed energy level. The particle therapy system modulates or reduces the energy of both particle beams using only a single common energy selection system. The beam transporting system may carry each particle beam from a respective cyclotron-based acceleration system to the energy selection system. The beam transporting system is adapted only to the fixed energy at which the particle beam emerges from the cyclotron. The construction with the common downstream energy selection system may, however, also be employed in other acceleration systems, such as synchrotron-based acceleration systems.

Different types of particles, such as protons or carbon ions, may be used for the acceleration and irradiation. The construction of the particle therapy system with one common energy selection system may be employed in particle therapy systems that are embodied for the joint use of protons and carbon ions.

The common energy selection system may include at least one wedgelike or platelike element.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 illustrates one embodiment of a cyclotron-based particle therapy system;

FIG. 2 illustrates one embodiment of an energy selection system with wedgelike beam shaping elements; and

FIG. 3 illustrates an energy selection system with platelike beam shaping elements.

DETAILED DESCRIPTION

FIG. 1 shows a particle therapy system 10. The particle therapy system 10 uses two different types of particles for the irradiation, for example, of tumors. The particles may be protons, carbon ions, pions, helium ions, or other particles.

The particle therapy system 10 may include a first cyclotron 11 and a second cyclotron 19. A first cyclotron 11 may accelerate a first type of particle to a first target energy level. The accelerated (resultant) particle beam is expelled from a first cyclotron 11 and carried, via a first beam transporting system 13 downstream of the cyclotron 11, to an energy selection system 15.

The energy selection system 15 may reduce the energy of the accelerated particle beam. For example, a first cyclotron 11 may accelerate protons to an energy of 230 MeV. The energy selection system 15 may reduce (slow down) energy of the proton beam to a variably adjustable energy level of between 230 MeV and 70 MeV.

The second cyclotron 19 may accelerate a second type of particle to a second target energy. The accelerated (resultant) particle beam is expelled from the second cyclotron 19 and carried to the same energy selection system 15 via a second beam transporting system 21 downstream of the cyclotron 19. The energy selection system 15 may set the energy of the second particle beam to a desired energy level, as described above for the first particle beam or for protons. The first cyclotron 11 and the second cyclotron 19 may be disposed side by side or arbitrarily relative to one another, for example, vertically one above the other.

Depending on which type of particle the particle therapy system is to be operated with, the generation of the particle beam may be done with the first or the second cyclotron.

The beam transporting systems 13, 21 may be disposed (inserted) between the cyclotrons 11, 19 and the energy selection system 15. The beam transporting system 13, 21 may be adapted to only one particle beam of the first type of particle with the first target energy and to a particle beam of the second type of particle with the second target energy, respectively. For example, the beam transporting system may use magnets.

In one embodiment, the particle therapy system 10 includes a beam transporting system 23. Once the particle beam has left the energy selection system 15, the downstream beam transporting system 23 carries (guides) the particle beam to the individual irradiation or treatment rooms 25. FIG. 1 shows three treatment rooms 25. In one treatment room 25, the accelerated particles are aimed at a body that is to be irradiated. The particles may be aimed at the body from a fixed direction. (e.g., in a “fixed-beam” room), or from various directions via a rotatable gantry 29 that can be moved about an axis 27.

In one embodiment, a charged particle beam is deflected by a magnet system transverse to the beam direction. In an irradiation process, which is known as raster scanning, the particle beam is scanned with a focal size of a few millimeters in layers over the target volume. Precise irradiation that conforms to the tumor is possible. For such stratified irradiation, the energy of the particle beam is finely adapted. Other irradiation processes are possible, such as spot scanning.

An irradiation process may include using passive beam shaping elements. During particle therapy, the particle beam may be flared out. A collimator and/or beam-shaping elements may be placed in the beam path, such that the particle beam is adapted to the shape of a tumor.

FIGS. 2 and 3 show embodiments of an energy selection system 15. In FIG. 2, wedgelike (wedge-shaped) beam-shaping elements 17, for example, made of carbon, are disposed into the beam path 16. In the energy selection system 15, the energy of the particle beam, which as a result of the acceleration by a cyclotron has a fixed energy, may be reduced to a desired magnitude by the wedgelike beam-shaping elements 17. The farther the wedgelike elements 17 are introduced into the beam path 16, the more the energy of the particle beam is reduced.

FIG. 3 shows another energy selection system 15. The energy selection system 15 shown in FIG. 3 functions similar to the energy selection system 15 shown in FIG. 2. In FIG. 3 the energy selection system 15 includes platelike (plate-shaped) beam-shaping elements 18. The platelike beam-shaping elements 18 may be disposed into the beam path 16. Depending on the total thickness of the platelike elements 18 through which the particle beam passes, the energy of the particle beam is reduced.

Various embodiments described herein can be used alone or in combination with one another. The forgoing detailed description has described only a few of the many possible implementations of the present invention. For this reason, this detailed description is intended by way of illustration, and not by way of limitation. It is only the following claims, including all equivalents that are intended to define the scope of this invention.

Claims (14)

1. A particle therapy system, comprising:
at least two acceleration units that are operable to accelerate particles to at least an irradiation energy level; and
a common energy selection system connected downstream of the at least two acceleration units, the common energy selection system being operable to reduce the energy of particles that have been accelerated by one of the acceleration units,
wherein the common energy selection system connects to and is upstream of a beam transporting system that is operable to carry the particles to at least one treatment room.
2. The particle therapy system as defined by claim 1, wherein the at least two acceleration units accelerate different types of particles.
3. The particle therapy system as defined by claim 1, wherein at least one of the acceleration units is a cyclotron acceleration system.
4. The particle therapy system as defined by claim 1, wherein the common energy selection system includes at least one wedge-shaped or plate-shaped element.
5. The particle therapy system as defined by claim 1, wherein the particle types are protons, carbon ions, pions, or helium ions.
6. The particle therapy system as defined by claim 2, wherein at least one of the acceleration units is a cyclotron acceleration system.
7. The particle therapy system as defined by claim 2, wherein the common energy selection system includes at least one wedge-like or platelike element.
8. The particle therapy system as defined by claim 2, wherein at least one of the particle types is protons or carbon ions.
9. The particle therapy system as defined by claim 1, wherein the common energy selection system is operable to reduce the energy of particles that have been accelerated by the acceleration units.
10. An energy selection system, comprising:
at least two beam transporting systems; and
a beam-shaping element that is operable to reduce an energy level of one or more accelerated particle beams,
wherein the at least two beam transporting systems carry at least two accelerated particle beams to the beam-shaping element, and
wherein the energy selection system connects to and is upstream of another beam transporting system that is operable to carry the at least two accelerated particle beams to at least one treatment room.
11. The energy selection system as claimed in claim 10, wherein the at least two beam transporting systems carry the at least two accelerated particle beams from two or more cyclotrons to the beam-shaping element.
12. The energy selection system as claimed in claim 10, wherein the beam-shaping element is a wedge-shaped beam-shaping element.
13. The energy selection system as claimed in claim 10, wherein the beam-shaping element is a plate-shaped beam-shaping element.
14. The energy selection system as claimed in claim 10, comprising a plurality of beam-shaping elements.
US12/110,889 2007-05-02 2008-04-28 Particle therapy system Active 2028-11-29 US7816657B2 (en)

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DE200710020599 DE102007020599A1 (en) 2007-05-02 2007-05-02 Particle therapy system
DE102007020599 2007-05-02
DEDE102007020599.8 2007-05-02

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8344340B2 (en) 2005-11-18 2013-01-01 Mevion Medical Systems, Inc. Inner gantry
US8581523B2 (en) 2007-11-30 2013-11-12 Mevion Medical Systems, Inc. Interrupted particle source
US8791656B1 (en) 2013-05-31 2014-07-29 Mevion Medical Systems, Inc. Active return system
US8927950B2 (en) 2012-09-28 2015-01-06 Mevion Medical Systems, Inc. Focusing a particle beam
US8933650B2 (en) 2007-11-30 2015-01-13 Mevion Medical Systems, Inc. Matching a resonant frequency of a resonant cavity to a frequency of an input voltage
US8941083B2 (en) 2007-10-11 2015-01-27 Mevion Medical Systems, Inc. Applying a particle beam to a patient
US9155186B2 (en) 2012-09-28 2015-10-06 Mevion Medical Systems, Inc. Focusing a particle beam using magnetic field flutter
US9185789B2 (en) 2012-09-28 2015-11-10 Mevion Medical Systems, Inc. Magnetic shims to alter magnetic fields
US9274067B2 (en) 2011-03-07 2016-03-01 Loma Linda University Medical Center Systems, devices and methods related to calibration of a proton computed tomography scanner
US9301384B2 (en) 2012-09-28 2016-03-29 Mevion Medical Systems, Inc. Adjusting energy of a particle beam
US9545528B2 (en) 2012-09-28 2017-01-17 Mevion Medical Systems, Inc. Controlling particle therapy
US9622335B2 (en) 2012-09-28 2017-04-11 Mevion Medical Systems, Inc. Magnetic field regenerator
US9661736B2 (en) 2014-02-20 2017-05-23 Mevion Medical Systems, Inc. Scanning system for a particle therapy system
US9681531B2 (en) 2012-09-28 2017-06-13 Mevion Medical Systems, Inc. Control system for a particle accelerator
US9723705B2 (en) 2012-09-28 2017-08-01 Mevion Medical Systems, Inc. Controlling intensity of a particle beam
US9730308B2 (en) 2013-06-12 2017-08-08 Mevion Medical Systems, Inc. Particle accelerator that produces charged particles having variable energies
US9950194B2 (en) 2014-09-09 2018-04-24 Mevion Medical Systems, Inc. Patient positioning system
US9962560B2 (en) 2013-12-20 2018-05-08 Mevion Medical Systems, Inc. Collimator and energy degrader
US10254739B2 (en) 2012-09-28 2019-04-09 Mevion Medical Systems, Inc. Coil positioning system
US10258810B2 (en) 2013-09-27 2019-04-16 Mevion Medical Systems, Inc. Particle beam scanning

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009040457B4 (en) * 2009-08-27 2013-05-29 Technische Universität Dresden Device for the selection of particles of specific energy from particle beams
US8217366B2 (en) 2009-11-02 2012-07-10 Electronics And Telecommunications Research Institute Carbon ion generating device and tumor treatment apparatus using the same
DE102011102977A1 (en) * 2011-05-23 2012-11-29 Gsi Helmholtzzentrum Für Schwerionenforschung Gmbh Multiple range modulators
JP5763218B2 (en) * 2012-01-16 2015-08-12 住友重機械工業株式会社 charged particle beam irradiation system
JP6552859B2 (en) * 2015-03-31 2019-07-31 住友重機械工業株式会社 Charged particle beam therapy system
CN107596579B (en) * 2017-10-12 2018-06-05 合肥中科离子医学技术装备有限公司 Based compact superconducting cyclotron proton therapy system

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1752992A1 (en) 1968-08-17 1971-07-29 Thielenhaus Maschf Device for grinding the ball grooves of the ball screws
US5039867A (en) * 1987-08-24 1991-08-13 Mitsubishi Denki Kabushiki Kaisha Therapeutic apparatus
DE19907098A1 (en) 1999-02-19 2000-08-24 Schwerionenforsch Gmbh Ion beam scanning system for radiation therapy e.g. for tumor treatment, uses energy absorption device displaced transverse to ion beam path via linear motor for altering penetration depth
US6580084B1 (en) 1999-09-14 2003-06-17 Hitachi, Ltd. Accelerator system
US20040069958A1 (en) 2001-02-05 2004-04-15 Ludwig Dahl Apparatus for generating and selecting ions used in a heavy ion cancer therapy facility
EP1430932A1 (en) 2002-12-20 2004-06-23 Siemens Aktiengesellschaft Ion beam facility
EP1477206A1 (en) 2003-05-13 2004-11-17 Hitachi, Ltd. Particle beam irradiation apparatus and treatment planning unit
US7141810B2 (en) 2004-09-28 2006-11-28 Hitachi, Ltd. Particle beam irradiation system

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1752992A1 (en) * 2005-08-12 2007-02-14 Siemens Aktiengesellschaft Apparatus for the adaption of a particle beam parameter of a particle beam in a particle beam accelerator and particle beam accelerator with such an apparatus

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1752992A1 (en) 1968-08-17 1971-07-29 Thielenhaus Maschf Device for grinding the ball grooves of the ball screws
US5039867A (en) * 1987-08-24 1991-08-13 Mitsubishi Denki Kabushiki Kaisha Therapeutic apparatus
DE19907098A1 (en) 1999-02-19 2000-08-24 Schwerionenforsch Gmbh Ion beam scanning system for radiation therapy e.g. for tumor treatment, uses energy absorption device displaced transverse to ion beam path via linear motor for altering penetration depth
US6891177B1 (en) * 1999-02-19 2005-05-10 Gesellschaft Fuer Schwerionenforschung Mbh Ion beam scanner system and operating method
US6580084B1 (en) 1999-09-14 2003-06-17 Hitachi, Ltd. Accelerator system
US20040069958A1 (en) 2001-02-05 2004-04-15 Ludwig Dahl Apparatus for generating and selecting ions used in a heavy ion cancer therapy facility
EP1430932A1 (en) 2002-12-20 2004-06-23 Siemens Aktiengesellschaft Ion beam facility
US6894300B2 (en) * 2002-12-20 2005-05-17 Siemens Aktiengesellschaft Ion beam facility
EP1477206A1 (en) 2003-05-13 2004-11-17 Hitachi, Ltd. Particle beam irradiation apparatus and treatment planning unit
US20040227104A1 (en) * 2003-05-13 2004-11-18 Koji Matsuda Particle beam irradiation apparatus, treatment planning unit, and particle beam irradiation method
US7141810B2 (en) 2004-09-28 2006-11-28 Hitachi, Ltd. Particle beam irradiation system

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
European Office Action dated Nov. 7, 2008 and English translation.
European Search Report dated Oct. 30, 2008 and English translation.
German Office Action dated Apr. 21, 2008 with English translation.
Manabu Mizota, et al., "The High-Energy Beam-Transport System for HIMAC", Mitsubishi Electric Advance, Mitsubishi Electric Corp., Tokyo, Japan, vol. 62, Jan. 1, 1995, p. 2-04, XP000905407, ISSN:0386-5096.

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US9925395B2 (en) 2005-11-18 2018-03-27 Mevion Medical Systems, Inc. Inner gantry
US10279199B2 (en) 2005-11-18 2019-05-07 Mevion Medical Systems, Inc. Inner gantry
US8907311B2 (en) 2005-11-18 2014-12-09 Mevion Medical Systems, Inc. Charged particle radiation therapy
US8916843B2 (en) 2005-11-18 2014-12-23 Mevion Medical Systems, Inc. Inner gantry
US8344340B2 (en) 2005-11-18 2013-01-01 Mevion Medical Systems, Inc. Inner gantry
US9452301B2 (en) 2005-11-18 2016-09-27 Mevion Medical Systems, Inc. Inner gantry
US8941083B2 (en) 2007-10-11 2015-01-27 Mevion Medical Systems, Inc. Applying a particle beam to a patient
US8933650B2 (en) 2007-11-30 2015-01-13 Mevion Medical Systems, Inc. Matching a resonant frequency of a resonant cavity to a frequency of an input voltage
US8581523B2 (en) 2007-11-30 2013-11-12 Mevion Medical Systems, Inc. Interrupted particle source
US8970137B2 (en) 2007-11-30 2015-03-03 Mevion Medical Systems, Inc. Interrupted particle source
US9274067B2 (en) 2011-03-07 2016-03-01 Loma Linda University Medical Center Systems, devices and methods related to calibration of a proton computed tomography scanner
US9880301B2 (en) 2011-03-07 2018-01-30 Loma Linda University Medical Center Systems, devices and methods related to calibration of a proton computed tomography scanner
US9185789B2 (en) 2012-09-28 2015-11-10 Mevion Medical Systems, Inc. Magnetic shims to alter magnetic fields
US9301384B2 (en) 2012-09-28 2016-03-29 Mevion Medical Systems, Inc. Adjusting energy of a particle beam
US9155186B2 (en) 2012-09-28 2015-10-06 Mevion Medical Systems, Inc. Focusing a particle beam using magnetic field flutter
US9545528B2 (en) 2012-09-28 2017-01-17 Mevion Medical Systems, Inc. Controlling particle therapy
US10254739B2 (en) 2012-09-28 2019-04-09 Mevion Medical Systems, Inc. Coil positioning system
US9681531B2 (en) 2012-09-28 2017-06-13 Mevion Medical Systems, Inc. Control system for a particle accelerator
US9706636B2 (en) 2012-09-28 2017-07-11 Mevion Medical Systems, Inc. Adjusting energy of a particle beam
US9723705B2 (en) 2012-09-28 2017-08-01 Mevion Medical Systems, Inc. Controlling intensity of a particle beam
US10155124B2 (en) 2012-09-28 2018-12-18 Mevion Medical Systems, Inc. Controlling particle therapy
US8927950B2 (en) 2012-09-28 2015-01-06 Mevion Medical Systems, Inc. Focusing a particle beam
US9622335B2 (en) 2012-09-28 2017-04-11 Mevion Medical Systems, Inc. Magnetic field regenerator
US10368429B2 (en) 2012-09-28 2019-07-30 Mevion Medical Systems, Inc. Magnetic field regenerator
US8791656B1 (en) 2013-05-31 2014-07-29 Mevion Medical Systems, Inc. Active return system
US9730308B2 (en) 2013-06-12 2017-08-08 Mevion Medical Systems, Inc. Particle accelerator that produces charged particles having variable energies
US10258810B2 (en) 2013-09-27 2019-04-16 Mevion Medical Systems, Inc. Particle beam scanning
US9962560B2 (en) 2013-12-20 2018-05-08 Mevion Medical Systems, Inc. Collimator and energy degrader
US9661736B2 (en) 2014-02-20 2017-05-23 Mevion Medical Systems, Inc. Scanning system for a particle therapy system
US9950194B2 (en) 2014-09-09 2018-04-24 Mevion Medical Systems, Inc. Patient positioning system

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CN101537232A (en) 2009-09-23
AT511886T (en) 2011-06-15
EP1987859B1 (en) 2011-06-08
US20080290299A1 (en) 2008-11-27
EP1987859A2 (en) 2008-11-05
DE102007020599A1 (en) 2008-11-06
CN101537232B (en) 2012-08-22
EP1987859A3 (en) 2008-12-10

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