US6670118B2 - Method for treating papillomavirus infections - Google Patents
Method for treating papillomavirus infections Download PDFInfo
- Publication number
- US6670118B2 US6670118B2 US09/189,172 US18917298A US6670118B2 US 6670118 B2 US6670118 B2 US 6670118B2 US 18917298 A US18917298 A US 18917298A US 6670118 B2 US6670118 B2 US 6670118B2
- Authority
- US
- United States
- Prior art keywords
- product
- grams
- lesion
- viral
- infections
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pest Control & Pesticides (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Agronomy & Crop Science (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
Description
Claims (3)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/189,172 US6670118B2 (en) | 1997-04-15 | 1998-11-10 | Method for treating papillomavirus infections |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83807197A | 1997-04-15 | 1997-04-15 | |
US92351697A | 1997-09-04 | 1997-09-04 | |
US09/189,172 US6670118B2 (en) | 1997-04-15 | 1998-11-10 | Method for treating papillomavirus infections |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US92351697A Continuation-In-Part | 1997-04-15 | 1997-09-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
US20010036920A1 US20010036920A1 (en) | 2001-11-01 |
US6670118B2 true US6670118B2 (en) | 2003-12-30 |
Family
ID=27125998
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/189,172 Expired - Fee Related US6670118B2 (en) | 1997-04-15 | 1998-11-10 | Method for treating papillomavirus infections |
Country Status (9)
Country | Link |
---|---|
US (1) | US6670118B2 (en) |
EP (1) | EP0975216A4 (en) |
JP (1) | JP2001524085A (en) |
KR (1) | KR20010006378A (en) |
CN (1) | CN1251969A (en) |
AU (1) | AU726830B2 (en) |
BR (1) | BR9808873A (en) |
CA (1) | CA2285572A1 (en) |
WO (1) | WO1998046077A1 (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006026604A3 (en) * | 2004-08-27 | 2006-12-07 | Advanced Viral Res Corp | Methods for promoting wound healing |
US20070207969A1 (en) * | 2002-05-28 | 2007-09-06 | Advanced Viral Research Corporation | Treatment of cancers of lymphocytic cells with product R |
US20090305944A1 (en) * | 2005-06-03 | 2009-12-10 | Bbm Holdings, Inc | Methods for Providing Palliative Care with AVR 118 |
US20090311236A1 (en) * | 2008-06-11 | 2009-12-17 | Immune @Work, Inc. | Therapeutic Peptide Compositions And Methods Of Making And Using Same |
US20100080820A1 (en) * | 1996-10-22 | 2010-04-01 | Bbm Holdings, Inc. | Preparation of a Therapeutic Composition |
US20160361374A1 (en) * | 2014-02-24 | 2016-12-15 | Ntd Labs, S. L. | Use of a casein hydrolysate as an antiviral agent |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004087139A1 (en) * | 2003-03-27 | 2004-10-14 | Boehringer Ingelheim International Gmbh | Antiviral combination of tipranavir and a further antiretroviral compound |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6303153B1 (en) * | 1996-10-22 | 2001-10-16 | Advanced Viral Research Corp. | Preparation of a therapeutic composition |
US6355226B1 (en) * | 1997-04-15 | 2002-03-12 | Advanced Viral Research Corp. | Topical treatment of skin disease and eye afflictions |
-
1998
- 1998-04-15 BR BR9808873-4A patent/BR9808873A/en not_active Application Discontinuation
- 1998-04-15 KR KR1019997009465A patent/KR20010006378A/en not_active Application Discontinuation
- 1998-04-15 WO PCT/US1998/007602 patent/WO1998046077A1/en not_active Application Discontinuation
- 1998-04-15 EP EP98918258A patent/EP0975216A4/en not_active Withdrawn
- 1998-04-15 AU AU71220/98A patent/AU726830B2/en not_active Ceased
- 1998-04-15 JP JP54426798A patent/JP2001524085A/en active Pending
- 1998-04-15 CN CN98804153A patent/CN1251969A/en active Pending
- 1998-04-15 CA CA002285572A patent/CA2285572A1/en not_active Abandoned
- 1998-11-10 US US09/189,172 patent/US6670118B2/en not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6303153B1 (en) * | 1996-10-22 | 2001-10-16 | Advanced Viral Research Corp. | Preparation of a therapeutic composition |
US6355226B1 (en) * | 1997-04-15 | 2002-03-12 | Advanced Viral Research Corp. | Topical treatment of skin disease and eye afflictions |
Non-Patent Citations (27)
Title |
---|
Anderson, Robert H. and Thompson, Ralph M., Treatment of Viral Syndrome with a Lipoprotein-Nucleic Acid Compound (Reticulose), A Report of Five Cases, Virginia Medical Monthly, 84: 347-353, 1957. |
Anderson, Robert H., Encephalitis, Symposium, pp. 39-52, 1960. |
Behbehani, Abbas M., Haberman Sol and Race, George J, The Effect of Reticulose on Viral Infections of Experimental Animals, Southern Medical Journal, Feb., 1962, 185-188. |
Brazier, Anne D., Method for in Vitro Antiviral Evaluation Human Immunodeficiency Virus (HIV), Personal Communication with Dr. Bernard Friedland, Oct. 4, 1989. |
Catterall, R.A., Lumpur, Kuala, A New Treatment of Herpes Zoster, Vaccinia And Chicken Pox, J. Roy. Coll. Gen. Practit., 1970, 19, 182. |
Chinnici, Angelo A., Reticulose in Treatment Aids patients, Personal Communication to William Bregman, Jul. 6, 1992. |
Cohen, Matthew, The Efficacy of a Peptide-Nucleic Acid Solution (Reticulose) for the Treatment of Hepatitis A and Hepatitis B-a Preliminary Controlled Human Clinical Trial, J. Roy. Soc. Health, Dec., 1992, 266-270. |
Cohen, Matthew, The Efficacy of a Peptide-Nucleic Acid Solution (Reticulose) for the Treatment of Hepatitis A and Hepatitis B—a Preliminary Controlled Human Clinical Trial, J. Roy. Soc. Health, Dec., 1992, 266-270. |
Cooke, Stanford B., Upper Respiratory Viral Manifestations, Clinical Symposium on Viral Diseases Demonstrating the Anti-viral Biotic Properties of the Drug Reticulose (Symposium), Sep., 1960, Miami Beach, Florida, pp. 25-32. |
Cott, Rafael A., Summary of 11 Cases of Viral Infections Treated with Reticulose, Private Communication with Advance Viral Research Corp., 1989. |
Friedland, Bernard, In Vitro Antiviral Activity of a Peptide-Nucleic Acid Solution Against the Human Immunodeficiency Virus and Influenza A Virus, J. Roy. Soc. Health, Oct. 1991, 170-171. |
Kempe, Henry C., Fulginiti, Vincent A., and Vincent, Leone St., Failure to Demonstrate Antiviral Activity of Reticulose, Diseases of Children, vol. 103, No. 5, 655-657, 1962. |
Kosaka, K. and Shimada, Y., Infectious Hepatitis, Symposium, pp. 61-74, 1960. |
Kuckku, Morris E., Herpetic Diseases, Symposium, pp. 7-13, 1960. |
Medoff, Lawrence R., Infectious Mononucleosis, Symposium, pp. 33-37, 1960. |
Mundschenk, David D., In Vitro Antiviral Activity of Reticulose vs Influenaz A, Personal Communication with William Bregman, May 1, 1990. |
Plucinski, Stanisloff J., Suspected Viral Varieties, Symposium, pp. 53-59, 1960. |
Resnick, Lionel, Anti-HIV in Vitro Activity of Two Samples of Peptide-nucleic Acid Solution, Personal Communication with Dr. Bernard Friedland, Dec. 22, 1989. |
Reynolds, Margaret R., Generalized Vaccinia Successfully Treated With Lipoprotein-Nucleic Acid Complex (Reticulose), Archives of Pediatrics, 77:421-422, 1960. |
Reynolds, Margaret R., Generalized Vaccinia, Symposium, pp. 5-6, 1960. |
Sanders, Murray, Controlled Animal Studies with Reticulose Illustrating the Interference of Lipoprotein-Nucleic Acid Complex in the Experimental Animal Infected with Human Pathogenic Viral Entities, Southern Medical Association Scientific Exhibit, Dallas, Texas, Nov., 1961. |
Schaeffer, Oden A., Influenza, Symposium, pp. 15-21, 1960. |
Seydel, Frank, Epidemic, Asian Influenza, Symposium, pp. 23-24, 1960. |
Treatment of Viral Diseases with A Lipo-protein Nucleic Acid Complex (Reticulose)-A Clinical Study, Scientific Exhibit: Virginia State Medical Society Meeting, Washington D.C., Nov., 1957. |
Treatment of Viral Diseases with A Lipo-protein Nucleic Acid Complex (Reticulose)—A Clinical Study, Scientific Exhibit: Virginia State Medical Society Meeting, Washington D.C., Nov., 1957. |
Webster et al , 1994, Academic Press, vol. 2, pp. 1013-1026, 1994.* * |
Wegryn, Stanley P., Marks, Robert A. and Baugh, John R., Herpes Gestationis, A Report of 2 Cases, American Journal of Obstetrics and Gynecology, 79:812-814, 1960. |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100080820A1 (en) * | 1996-10-22 | 2010-04-01 | Bbm Holdings, Inc. | Preparation of a Therapeutic Composition |
US8084239B2 (en) | 1996-10-22 | 2011-12-27 | Ohr Pharmaceuticals, Inc | Preparation of a therapeutic composition |
US20070207969A1 (en) * | 2002-05-28 | 2007-09-06 | Advanced Viral Research Corporation | Treatment of cancers of lymphocytic cells with product R |
US7465711B2 (en) | 2002-05-28 | 2008-12-16 | Advanced Viral Research Corporation | Treatment of cancers of lymphocytic cells with product R |
WO2006026604A3 (en) * | 2004-08-27 | 2006-12-07 | Advanced Viral Res Corp | Methods for promoting wound healing |
US20090305944A1 (en) * | 2005-06-03 | 2009-12-10 | Bbm Holdings, Inc | Methods for Providing Palliative Care with AVR 118 |
US20090311236A1 (en) * | 2008-06-11 | 2009-12-17 | Immune @Work, Inc. | Therapeutic Peptide Compositions And Methods Of Making And Using Same |
US20160361374A1 (en) * | 2014-02-24 | 2016-12-15 | Ntd Labs, S. L. | Use of a casein hydrolysate as an antiviral agent |
US10772927B2 (en) * | 2014-02-24 | 2020-09-15 | Ntd Labs, S.L. | Use of a casein hydrolysate as an antiviral agent |
Also Published As
Publication number | Publication date |
---|---|
BR9808873A (en) | 2000-07-11 |
AU7122098A (en) | 1998-11-11 |
AU726830B2 (en) | 2000-11-23 |
EP0975216A1 (en) | 2000-02-02 |
CN1251969A (en) | 2000-05-03 |
CA2285572A1 (en) | 1998-10-22 |
KR20010006378A (en) | 2001-01-26 |
US20010036920A1 (en) | 2001-11-01 |
WO1998046077A1 (en) | 1998-10-22 |
EP0975216A4 (en) | 2002-05-02 |
JP2001524085A (en) | 2001-11-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: ADVANCED VIRAL RESEARCH CORP., NEW YORK Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:HIRSCHMAN, SHALOM Z.;REEL/FRAME:015810/0723 Effective date: 20040825 |
|
REMI | Maintenance fee reminder mailed | ||
LAPS | Lapse for failure to pay maintenance fees | ||
STCH | Information on status: patent discontinuation |
Free format text: PATENT EXPIRED DUE TO NONPAYMENT OF MAINTENANCE FEES UNDER 37 CFR 1.362 |
|
FP | Expired due to failure to pay maintenance fee |
Effective date: 20071230 |
|
AS | Assignment |
Owner name: TRIAD BIOTHERAPEUTICS, INC., NEW YORK Free format text: FORECLOSURE BY THIRD PARTY;ASSIGNOR:YA GLOBAL INVESTMENTS, L.P. (F/K/A CORNELL CAPITAL PARTNERS, L.P.);REEL/FRAME:022510/0187 Effective date: 20090318 Owner name: ADVANCED VIRAL RESEARCH CORP., NEW YORK Free format text: FORECLOSURE BY THIRD PARTY;ASSIGNOR:YA GLOBAL INVESTMENTS, L.P. (F/K/A CORNELL CAPITAL PARTNERS, L.P.);REEL/FRAME:022510/0187 Effective date: 20090318 |
|
AS | Assignment |
Owner name: YA GLOBAL INVESTMENTS, L.P. (F/K/A CORNELL CAPITAL Free format text: CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNOR/ASSIGNEE NAMES PREVIOUSLY RECORDED ON REEL 022510 FRAME 0187;ASSIGNORS:ADVANCED VIRAL RESEARCH CORP.;TRIAD BIOTHERAPEUTICS, INC.;REEL/FRAME:022542/0001 Effective date: 20090318 |
|
AS | Assignment |
Owner name: BBM HOLDINGS, INC., UTAH Free format text: CORRECTIVE ASSIGNMENT TO CORRECT THE RECEIVING PARTY PREVIOUSLY RECORDED ON REEL 022542 FRAME 0001;ASSIGNORS:ADVANCED VIRAL RESEARCH CORP.;TRIAD BIOTHERAPEUTICS, INC.;REEL/FRAME:022629/0569 Effective date: 20090318 |
|
AS | Assignment |
Owner name: YA GLOBAL INVESTMENTS, L.P., NEW JERSEY Free format text: SECURITY AGREEMENT;ASSIGNOR:BBM HOLDINGS, INC.;REEL/FRAME:022708/0679 Effective date: 20090318 |