US6454805B1 - Interbody cavity implant, in particular for cervical vertebrae - Google Patents

Interbody cavity implant, in particular for cervical vertebrae Download PDF

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Publication number
US6454805B1
US6454805B1 US09/786,179 US78617901A US6454805B1 US 6454805 B1 US6454805 B1 US 6454805B1 US 78617901 A US78617901 A US 78617901A US 6454805 B1 US6454805 B1 US 6454805B1
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United States
Prior art keywords
implant according
anchoring
anchoring member
opening
implant
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Expired - Lifetime
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US09/786,179
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English (en)
Inventor
Christian Baccelli
Frédéric Conchy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stryker Spine SAS
Stryker European Operations Holdings LLC
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Dimso SA
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Assigned to DIMSO (DISTRIBUTION MEDICALE DU SUD-OUEST) reassignment DIMSO (DISTRIBUTION MEDICALE DU SUD-OUEST) ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: BACCELLI, CHRISTIAN, CONCHY, FREDERIC
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Publication of US6454805B1 publication Critical patent/US6454805B1/en
Assigned to STRYKER SPINE reassignment STRYKER SPINE CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: DIMSO SA (DISTRIBUTION MEDICALES DU SUD-OUEST)
Assigned to STRYKER EUROPEAN HOLDINGS VI, LLC reassignment STRYKER EUROPEAN HOLDINGS VI, LLC NUNC PRO TUNC ASSIGNMENT (SEE DOCUMENT FOR DETAILS). Assignors: STRYKER SPINE SAS
Assigned to STRYKER EUROPEAN HOLDINGS I, LLC reassignment STRYKER EUROPEAN HOLDINGS I, LLC NUNC PRO TUNC ASSIGNMENT (SEE DOCUMENT FOR DETAILS). Assignors: STRYKER EUROPEAN HOLDINGS VI, LLC
Anticipated expiration legal-status Critical
Assigned to STRYKER EUROPEAN HOLDINGS III, LLC reassignment STRYKER EUROPEAN HOLDINGS III, LLC NUNC PRO TUNC ASSIGNMENT (SEE DOCUMENT FOR DETAILS). Assignors: STRYKER EUROPEAN HOLDINGS I, LLC
Assigned to STRYKER EUROPEAN OPERATIONS HOLDINGS LLC reassignment STRYKER EUROPEAN OPERATIONS HOLDINGS LLC CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: STRYKER EUROPEAN HOLDINGS III, LLC
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442—Intervertebral or spinal discs, e.g. resilient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00011—Metals or alloys

Definitions

  • the present invention relates in a general manner to interbody cages intended to partially or completely replace an intervertebral disc in surgical treatment of the spine and to permit bone fusion between the overlying and underlying vertebral plates.
  • a number of types of interbody cages are already known in the prior art.
  • One cage which is particularly widely used is made up of a one-piece body made of biocompatible material such as a titanium alloy or a stainless steel, of which the upper surface and the lower surface have reliefs such as serrations of triangular cross section which are intended to provide anchoring in the overlying and underlying vertebral plates when the distraction effected between the vertebrae for the purpose of fitting the implant is released.
  • Such a cage is also provided with at least one opening which passes through the body from top to bottom and opens out on its upper and lower faces. The cavity constituted by this opening is filled with an osteogenic material or bone graft so as to ensure bone growth through it between the vertebral plates and, in the long term, rigid bone fusion between these plates.
  • the present invention aims to overcome these limitations of the prior art and to propose a novel implant of the interbody cage type which is well adapted to implantation in the region of the cervical vertebrae and which is able to be joined to the vertebral plates with an excellent quality of anchoring.
  • Another object of the invention is to propose an implant of the interbody cage type whose fitting is particularly simple and whose weight can be reduced compared with the entirely metal cages of the prior art, and whose manufacture can therefore be made simpler and less expensive.
  • the invention proposes an implant of the interbody cage type, particularly for cervical vertebrae, comprising a body which has an upper face and a lower face, which are able to bear on the overlying and underlying vertebral plates, and which also comprises at least one through-opening which opens out on the said upper and lower faces, characterized in that it additionally comprises an anchoring member mounted in such a way as to be able to move in the said opening, the said anchoring member comprising a bearing part adjacent to a first vertebral plate, and at least one projecting anchoring element extending from the said bearing part in the direction of the opposite vertebral plate, such that when the implant is compressed between the vertebral plates, the said anchoring member is stressed by the first vertebral plate in the area of the said bearing part so as to move in relation to the body and so that the said projecting element at least provided juts out from that face of the body turned toward the opposite vertebral plate and anchors in the latter.
  • the body has, on at least one of its upper and lower faces, complementary anchoring arrangements,
  • the said anchoring member has a plurality of projecting elements
  • the said projecting elements are elongate and essentially parallel to one another
  • the projecting anchoring element or each projecting anchoring element has the form of a rod with a pointed free end
  • the said opening of the body has a bearing arrangement for the said anchoring member in order to limit the course of movement of the latter caused by the said first vertebral plate,
  • the said arrangement consists of a shoulder between two parts of different sizes of the said opening
  • the anchoring member has a plurality of projecting anchoring elements all fitting tightly into the smaller-sized part of the said opening,
  • the said bearing part of the anchoring member has the form of a ring in which a central opening ensures continuity of passage between the upper and lower faces of the body, through the said opening of the body,
  • the body has a generally rounded external form, with zones of greater curvature and zones of lesser curvature,
  • the said opening of the body has a contour with a form similar to the said outer form of the body
  • the anchoring member is provided with a plurality of projecting elements situated in the vicinity of zones of greater curvature of the said opening and received in recesses formed in these zones,
  • one of the upper and lower faces of the body is convex
  • the bearing part of the anchoring member is generally plane
  • the body is made of a biocompatible polymer material such as polyetherether ketone,
  • the anchoring member is made of a biocompatible metal alloy.
  • FIG. 1 is a perspective view of an implant according to the invention
  • FIG. 2 is a front elevation view of the implant in FIG. 1,
  • FIG. 3 is a bottom view of the implant in FIGS. 1 and 2,
  • FIG. 4 is a top view of the implant in FIGS. 1 to 3 .
  • FIG. 5 is a longitudinal sectional view along the line V—V in FIG. 4,
  • FIG. 6 is a transverse sectional view along the line VI—VI in FIG. 4, in a first position of the implant, and
  • FIG. 7 is a view analogous to FIG. 6, in a second position of the implant.
  • an implant which is intended to form an interbody cage between two vertebral plates, preferably in the area of the cervical vertebrae, and which is made up of two parts, namely an outer cage body 10 and an inner reinforcement 20 .
  • the cage body has in this case, seen from above, a generally triangular contour with rounded corners. Other contours, preferably all with rounded corners, can also be adopted.
  • the body 10 has a generally plane upper face 14 provided with serrations 141 of triangular cross section, extending in a direction essentially perpendicular to the direction of fitting between the vertebral plates, and intended to participate in the anchoring in the overlying vertebral plate.
  • the lower face 13 of the body has for its part a convexity which is adapted to be essentially complementary to the natural concavity of the upper face of the underlying cervical vertebral plate.
  • This lower face 13 also has serrations 131 providing the anchoring in the said underlying vertebral plate.
  • a generally smooth peripheral face 12 Extending between the upper and lower faces is a generally smooth peripheral face 12 , in a front region of which there is an opening 121 , preferably provided with a thread, the latter allowing the implant to be mounted at the end of an instrument, of a type conventional per se.
  • the body 10 is passed through by a cavity 11 which opens out on its upper face and on its lower face, this cavity being made up of an upper part 111 and a lower part 112 which is slightly wider than the upper part, so as to define a shoulder 113 at the transition between these parts, for reasons explained below.
  • the wall 16 defining the cavity 11 has the same form as the outer contour of the body 10 , here generally triangular with rounded corners.
  • the reinforcement 20 is made up of a component which is designed to be able to be received inside the cavity 11 .
  • This reinforcement has at its base a ring 22 which extends in a generally horizontal plane and whose outer contour substantially matches, over at least a substantial part of its length, the shape of the wall of the lower part 112 of the cavity 11 of the body 10 , in such a way as to be able to be guided in vertical translation in the said lower part.
  • This ring is passed through by a central opening 221 .
  • spikes 21 Extending upward from the ring in this case there are three spikes 21 in the form of cylindrical rods whose upper end is conical in order to form a point directed upward. These spikes preferably extend from the three regions of the ring corresponding to the three “corners” of the rounded triangle formed by the cavity 11 of the body 10 and are positioned in such a way as to extend substantially along the inner wall defining the narrower top part 111 of the said cavity, so as to also form a guide for the said vertical translation.
  • the spikes 21 are here arranged level with the outer edge of the ring 22 , while the wall 16 in the area of the upper part 111 of the cavity has locally, in the area of the spikes 21 , shallow recesses 161 intended to form cradles for the respective spikes ensuring the abovementioned guiding.
  • the central opening 221 of the ring makes it possible to conserve the continuity of passage between the upper face and the lower face of the body 10 , as defined by its cavity 11 .
  • the implant is fitted by placing the reinforcement 20 in the body 10 in the position illustrated in FIGS. 2 and 6, that is to say in such a way that the spikes 21 are set slightly back from or are flush with the upper face 14 of the body 10 .
  • the internal space of the implant defined by the cavity 11 is filled partly or completely with bone graft or an osteogenic substance.
  • the distraction between the cervical vertebral plates being effected with the aid of instrumentation which is conventional per se, the implant is placed between these plates.
  • the implant is compressed between the plates, and the lower plate, which it will be recalled has a natural concavity, stresses the reinforcement 20 upward by acting on the area of the ring 22 , the flatness of which means that at the moment of fitting, some of its regions jut downward from the convex lower face 13 of the body.
  • the lower vertebral plate pushes the reinforcement 20 upward so as to cause the spikes 21 to jut upward beyond the upper face 14 of the body (see FIG. 7 ), and the pointed ends of these spikes penetrate the upper vertebral plate in order thereby to ensure particularly effective anchoring.
  • the serrations 131 , 141 for their part ensure secondary anchoring, which completes the main anchoring realized by the spikes 21 .
  • the stop formed by the shoulder 113 makes it possible to limit the movement of the reinforcement 20 upward, and thus to effectively control the degree of penetration of the spikes in the upper vertebral plate, given that excessive penetration risks weakening the vertebral body.
  • the ring 22 of the reinforcement 2 is substantially in a position flush with the lower face 13 of the body 10 , so that the body bears against the lower vertebral plate under good conditions over the maximum surface area.
  • the reinforcement 20 by virtue of its shape being complementary with the inside of the body 10 , fulfills a function of reinforcing this body. It is thus particularly advantageous to form the reinforcement 20 using a biocompatible metal alloy such as a titanium alloy or a stainless steel, while the body 10 can be made of a biocompatible polymer such as polyetherether ketone, without compromising the strength of the implant.
  • the fact that the reinforcement 20 is metal permits post-surgical verification of the stability of the implant by means of radiography.
  • the reinforcement 20 has in this case three main functions, namely a main anchoring function, a function of reinforcement of the body and a function of radiographic monitoring.
  • the horizontal section of the cavity 11 it is preferable, in order to ensure stable bone fusion, for the horizontal section of the cavity 11 to occupy at least a quarter of the overall horizontal section of the implant.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
US09/786,179 1998-09-04 1999-09-03 Interbody cavity implant, in particular for cervical vertebrae Expired - Lifetime US6454805B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9811175A FR2782914B1 (fr) 1998-09-04 1998-09-04 Implant de type cage intersomatique, notamment pour vertebres cervicales
FR9911175 1998-09-04
PCT/FR1999/002107 WO2000013618A1 (fr) 1998-09-04 1999-09-03 Implant de type cage intersomatique, notamment pour vertebres cervicales

Publications (1)

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US6454805B1 true US6454805B1 (en) 2002-09-24

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US09/786,179 Expired - Lifetime US6454805B1 (en) 1998-09-04 1999-09-03 Interbody cavity implant, in particular for cervical vertebrae

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US (1) US6454805B1 (ja)
EP (1) EP1109515B1 (ja)
JP (1) JP4048713B2 (ja)
KR (1) KR20010082192A (ja)
AT (1) ATE285206T1 (ja)
AU (1) AU775236B2 (ja)
CA (1) CA2342714C (ja)
DE (2) DE69922813T2 (ja)
ES (1) ES2167291T1 (ja)
FR (1) FR2782914B1 (ja)
WO (1) WO2000013618A1 (ja)
ZA (1) ZA200101926B (ja)

Cited By (38)

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Publication number Priority date Publication date Assignee Title
US20030028249A1 (en) * 1999-10-18 2003-02-06 Stryker Spine Intervertebral implant with toothed faces
US20030135278A1 (en) * 2002-01-17 2003-07-17 Concept Matrix, Llc Intervertebral disk prosthesis
US20030135276A1 (en) * 2002-01-17 2003-07-17 Concept Matrix, Llc Vertebral defect device
US6613090B2 (en) * 1998-01-23 2003-09-02 Aesculap Ag & Co. Kg Intervertebral implant
US6719794B2 (en) 2001-05-03 2004-04-13 Synthes (U.S.A.) Intervertebral implant for transforaminal posterior lumbar interbody fusion procedure
US20040225366A1 (en) * 2003-02-12 2004-11-11 Sdgi Holdings, Inc. Articular disc prosthesis for anterior-oblique insertion
US20050096744A1 (en) * 2003-11-05 2005-05-05 Sdgi Holdings, Inc. Compressible corpectomy device
US20050267471A1 (en) * 2004-05-04 2005-12-01 Lutz Biedermann Flexible space holder
US20070208423A1 (en) * 2001-05-03 2007-09-06 Dominique Messerli Intervertebral Implant for Transforminal Posterior Lumbar Interbody Fusion Procedure
US20080015695A1 (en) * 2006-04-28 2008-01-17 Concept Matrix, Llc Dual composition vertebral defect device
US20080249629A1 (en) * 2002-01-17 2008-10-09 Concept Matrix Llc Vertebral defect device
US7918876B2 (en) 2003-03-24 2011-04-05 Theken Spine, Llc Spinal implant adjustment device
US20110160860A1 (en) * 2009-12-31 2011-06-30 Rhausler, Inc. Cervical spacer
US8142508B1 (en) 2007-07-02 2012-03-27 Theken Spine, Llc Spinal cage having deployable member which is removable
US20120116457A1 (en) * 2010-11-06 2012-05-10 Limited Liability Company; Stabilizer for assisting stabilization of a spinal implant and method of using the stabilizer
US8267997B2 (en) 2007-11-12 2012-09-18 Theken Spine, Llc Vertebral interbody compression implant
US8292958B1 (en) 2007-07-02 2012-10-23 Theken Spine, Llc Spinal cage having deployable member
US8545562B1 (en) 2007-07-02 2013-10-01 Theken Spine, Llc Deployable member for use with an intervertebral cage
US8795167B2 (en) 2011-11-15 2014-08-05 Baxano Surgical, Inc. Spinal therapy lateral approach access instruments
US8864829B1 (en) 2007-07-02 2014-10-21 Theken Spine, Llc Spinal cage having deployable member
US9216096B2 (en) 2010-03-16 2015-12-22 Pinnacle Spine Group, Llc Intervertebral implants and related tools
US9380932B1 (en) 2011-11-02 2016-07-05 Pinnacle Spine Group, Llc Retractor devices for minimally invasive access to the spine
CN105726170A (zh) * 2016-02-03 2016-07-06 广州粤倍生物科技有限公司 一种个性化骨肉瘤颈椎假体
US9408718B2 (en) 2009-12-31 2016-08-09 Rhausler, Inc. Inter-vertebral implant with angled plate
US20170027712A1 (en) * 2007-03-07 2017-02-02 Nuvasive, Inc. System and methods for spinal fusion
US9693876B1 (en) 2012-03-30 2017-07-04 Ali H. MESIWALA Spinal fusion implant and related methods
US9707100B2 (en) 2015-06-25 2017-07-18 Institute for Musculoskeletal Science and Education, Ltd. Interbody fusion device and system for implantation
US20180093598A1 (en) * 2016-10-03 2018-04-05 Toyota Jidosha Kabushiki Kaisha Vehicle seat
US10070970B2 (en) 2013-03-14 2018-09-11 Pinnacle Spine Group, Llc Interbody implants and graft delivery systems
US10342674B2 (en) 2007-07-02 2019-07-09 Theken Spine, Llc Spinal cage having deployable member
WO2019200368A1 (en) * 2018-04-13 2019-10-17 Ali Innovative Spine Solutions Interfixated cervical stabilization system
US10624757B2 (en) 2015-04-09 2020-04-21 Centinel Spine, Llc Spinal implants configured for tissue sparing angle of insertion and related methods
US10905567B2 (en) 2019-04-26 2021-02-02 Warsaw Orthopedic, Inc. Spinal implant system and method
USD948048S1 (en) 2019-04-26 2022-04-05 Warsaw Orthopedic, Inc. Surgical implant
USD955579S1 (en) 2019-04-26 2022-06-21 Warsaw Orthopedic, Inc. Surgical implant
USD957639S1 (en) 2013-03-15 2022-07-12 Medtronic, Inc. Implantable cardiac monitor
US11872143B2 (en) 2016-10-25 2024-01-16 Camber Spine Technologies, LLC Spinal fusion implant
US11877935B2 (en) 2016-10-18 2024-01-23 Camber Spine Technologies, LLC Implant with deployable blades

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US6635087B2 (en) 2001-08-29 2003-10-21 Christopher M. Angelucci Laminoplasty implants and methods of use
DK175391B1 (da) * 2002-02-13 2004-09-20 Danfoss As Implantat til columna og fremgangsmåde til fremstilling heraf
US7192447B2 (en) 2002-12-19 2007-03-20 Synthes (Usa) Intervertebral implant
KR101276414B1 (ko) * 2004-05-04 2013-06-19 비이더만 테크놀로지스 게엠베하 & 코. 카게 유연성 스페이스 홀더
EP2457538A4 (en) * 2009-07-22 2015-03-25 Next21 Kk UNIT AND SYSTEM FOR CONSTRUCTING ARTIFICIAL BONE
CN105055056B (zh) * 2015-08-28 2017-03-29 四川大学华西医院 颈椎钩椎关节融合器

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Cited By (79)

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Publication number Priority date Publication date Assignee Title
US6613090B2 (en) * 1998-01-23 2003-09-02 Aesculap Ag & Co. Kg Intervertebral implant
US20030028249A1 (en) * 1999-10-18 2003-02-06 Stryker Spine Intervertebral implant with toothed faces
US7637950B2 (en) * 1999-10-18 2009-12-29 Stryker Spine Intervertebral implant with toothed faces
US20070208423A1 (en) * 2001-05-03 2007-09-06 Dominique Messerli Intervertebral Implant for Transforminal Posterior Lumbar Interbody Fusion Procedure
US8435300B2 (en) 2001-05-03 2013-05-07 DePuy Synthes Products, LLC Intervertebral implant for transforaminal posterior lumbar interbody fusion procedure
US8690949B2 (en) 2001-05-03 2014-04-08 DePuy Synthes Products, LLC Intervertebral implant for transforaminal posterior lumbar interbody fusion procedure
US6719794B2 (en) 2001-05-03 2004-04-13 Synthes (U.S.A.) Intervertebral implant for transforaminal posterior lumbar interbody fusion procedure
US20040172133A1 (en) * 2001-05-03 2004-09-02 Synthes(U.S.A.) Intervertebral Implant for transforaminal posterior lumbar interbody fusion procedure
USRE46647E1 (en) 2001-05-03 2017-12-26 DePuy Synthes Products, Inc. Intervertebral implant for transforaminal posterior lumbar interbody fusion procedure
US20050043798A1 (en) * 2002-01-17 2005-02-24 Concept Matrix, Llc Intervertebral disk prosthesis methods of use
US20100100140A1 (en) * 2002-01-17 2010-04-22 Concept Matrix, Llc Insertion tool for a vertebral defect device
US8137402B2 (en) 2002-01-17 2012-03-20 Concept Matrix Llc Vertebral defect device
US7011684B2 (en) 2002-01-17 2006-03-14 Concept Matrix, Llc Intervertebral disk prosthesis
US20060155378A1 (en) * 2002-01-17 2006-07-13 Concept Matrix, Llc Intervertebral disk prosthesis
US7105023B2 (en) 2002-01-17 2006-09-12 Concept Matrix, L.L.C. Vertebral defect device
US20070016299A1 (en) * 2002-01-17 2007-01-18 Concept Matrix, Llc Vertebral Defect Device
US20050075645A1 (en) * 2002-01-17 2005-04-07 Eckman Walter W. Methods of installing a vertebral defect device
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KR20010082192A (ko) 2001-08-29
EP1109515A1 (fr) 2001-06-27
CA2342714A1 (fr) 2000-03-16
JP2002524140A (ja) 2002-08-06
DE1109515T1 (de) 2002-08-22
FR2782914B1 (fr) 2000-12-01
DE69922813T2 (de) 2005-11-10
CA2342714C (fr) 2007-10-23
ZA200101926B (en) 2001-10-11
FR2782914A1 (fr) 2000-03-10
ATE285206T1 (de) 2005-01-15
AU5520999A (en) 2000-03-27
ES2167291T1 (es) 2002-05-16
WO2000013618A1 (fr) 2000-03-16
JP4048713B2 (ja) 2008-02-20
EP1109515B1 (fr) 2004-12-22
AU775236B2 (en) 2004-07-22
DE69922813D1 (de) 2005-01-27

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