US6314822B1 - Peak flow meter - Google Patents

Peak flow meter Download PDF

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US6314822B1
US6314822B1 US09/268,005 US26800599A US6314822B1 US 6314822 B1 US6314822 B1 US 6314822B1 US 26800599 A US26800599 A US 26800599A US 6314822 B1 US6314822 B1 US 6314822B1
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air
stator
flow
valve
directing
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Thomas McDonald Ford
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/087—Measuring breath flow
    • A61B5/09—Measuring breath flow using an element rotated by the flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/087—Measuring breath flow
    • A61B5/0873—Measuring breath flow using optical means

Definitions

  • the present invention is a Continuation-in-Part application of Ser. No. 08/849,647 filed on May 29, 1997 (now abandoned) based on International (PCT) Patent Application No. PCT/GB95/02793, filed Nov. 29, 1995.
  • This invention relates to the field of apparatus for measuring lung function.
  • the present invention relates to an air-flow valve for measuring the volume of air which can be expelled from the lungs and to a device incorporating such a valve to give improved indication of lung function.
  • the amount of air inspired or expired per breath is approximately 500 ml.
  • the expiratory reserve-volume can be expired—approximately 750-1000 ml in adults.
  • Vital capacity is the maximum volume of air which can be expelled from the lungs by a forceful effort, following a deliberate inhalation of the maximum volume possible. This vital capacity is normally of the order of 4.8 liters in men and 3.2 liters in women, but can be substantially reduced in asthmatics and people with other bronchial problems. The vital capacity and/or the ability to exhale thus provides a good indication of a subject's function.
  • a spring-loaded device such as a piston
  • An alternative method involves the use of a device containing a hot wire. Exhaled air passes over the hot wire, cooling it and a measure of the degree of cooling thus provides an indication of lung function. Again the device may not be sensitive enough for some objects. In addition the difficulty in accurately measuring the degree of cooling further affects the sensitivity.
  • a further method involves the use of rotary blades or a turbine.
  • Exhaled air causes the blades to rotate and this motion is detected and translated into an indication of lung function.
  • Turbines generally are heavy for their size and do not provide the required sensitivity.
  • Rotary blade devices are generally arranged so that the exhaled air impinges on the edges of the blades (i.e. that is, perpendicular to their mountings) and, again, the inertia of the device will affect its sensitivity. This is particularly important for testing subjects with poor lung function.
  • Breath volumeters of this type are exemplified by the disclosure of German Patent Specification No. DE-A-1803325 (VEB MEDIZINTECHNIK LEIPZIZ) which describes a breath volumeter having a rotor fitted with a twin-armed vane arranged centrally below a semi-circularly shaped stator attached to the meter casing.
  • the stator has a roughly semi-cross-section. In use, this arrangement suffers the disadvantage of developing a significant back-pressure in the device which is undesirable as it adversely affects the sensitivity and efficiency of the device.
  • FEV 1 Force Expired Volume
  • This parameter which is a measure of expired volume per second after initial exhilation and gives an indication of vital lung capacity and tidal reserve, is particularly important for assessing bronchitis and similar conditions. If back-pressure in a device is too low, a poor indication of vital capacity is received. Conversely, if back-pressure is too high, subjects having poor lung function will be unable to provide sufficient force to operate the device. Sensitivity of the device will also be adversely affected.
  • FEV 1 Force Expired Volume
  • U.S. Pat. No. 4,292,853, issued Oct. 6, 1981 to Williams et al discloses a respiratory air or gas flow volume indicating instrument having a slotted stator for directing exhaled air onto a rotor.
  • a barrier and a shaped gallery about the stator air is constrained to flow in one direction about the stator, through the stator slots onto the blades or vanes of the rotor.
  • the rotor spindle to which the vanes are axially fixed, drives a pointer through a counting gear box to indicate the volume of air flow.
  • the U.S. Pat. No. 4,292,853 arrangement possesses the disadvantageous features referred to above. Firstly, the inertia of the rotor which is connected to a gearbox limits the allowable sensitivity and could not be used for accurate peak flow measurement. Secondly, air flow from the inlet can directly impinge the rotor allowing food particles, sputum or excessive vapour to adhere thereto. Additionally, the construction disclosed does not allow for easy disassembly and cleaning. Further, mechanical coupling of the rotor to a counting mechanism allows only for measurement of one parameter, in this case, volume flow. Finally, as the flow of air is constrained in the gallery, back pressure is relatively high (although stated to be tolerable) even though the flow path is relatively simple. The air flow path described is an inlet air flow perpendicular to the rotational axis of the rotor and an angular deflection into the gallery before being directed spirally inwards to impinge the rotor vanes.
  • U.S. Pat. No. 4,294,262 issued Oct. 13, 1981 to Williams et al describes a respirometer having a circular chamber having a rotor therein.
  • the arrangement disclosed is essentially that forming part of U.S. Pat. No. 4,292,853 but having magnets mounted on radial arms rotatable with the rotor spindle.
  • the magnets co-operate with at least one magnetic field sensitive device arranged to sense the rotation of the rotor. An electrical output is then available for manipulation to obtain the required respiratory parameters.
  • the invention concerns the advantageous manipulation or redirection of an air-flow in an apparatus for measuring respiratory function.
  • an air-flow valve for use in a device for measuring air-flow, said valve including at least one rotary blade means comprising a planar surface free along at least one edge, for detecting air-flow thereabout, and a stator having at least one air-directing aperture positioned at, or adjacent, the outer edge of said blade means or the outermost part of the path traced by the same, said aperture being adapted to alter the direction of air-flow incident on said valve from a first direction to a second altered direction, whereby said direction-altered air-flow provides a force which causes said blade means to move, said first direction being substantially parallel to the rotational axis of said blade means and said direction being tangential to the rotational axis of said blade means and said second altered direction being perpendicular to or at least towards the planar surface of said blade means.
  • the air-directing apertures or slits are profiled angularly deflect the air-flow to direct it to or towards the planar surface of the blade so causing the blade to turn.
  • a valve body for housing the stator and rotor is provided, at least part of said valve body, in the region of said blade means, being transparent or translucent.
  • a motion detecting means which relies on the transmission and detection of an infra-red or light beam can be used with the valve.
  • apertures are provided in the valved body to allow the passage of either an infra-red or light beam therethrough.
  • the blade means rotates through a pre-determined sector, which sector includes the path of the infra-red or light beam, interruptible by the passage of the blade means therethrough.
  • Air-directing means are associated with each of the air-directing apertures to guide air from an annular chamber around the stator through the apertures onto the planar surface of the blade.
  • the apertures which are equi-spaced about the stator are shaped as air-directing means as the apertures are profiled to angularly deflect air into a direction tangential to the rotor axis.
  • the stator includes a plurality of fins positioned around the stator substantially adjacent each of said air-directing apertures.
  • the air-directing means comprises a plurality of air-flow guides positioned substantially adjacent each of said air-directing apertures, the air-flow guides being adapted to facilitate the change in air-flow direction from said first direction to said second direction.
  • said plurality of air-flow guides are formed as a valve insert adapted to cooperate with the stator, said guides being positioned to correspond to the air-directing apertures of the stator.
  • the air-flow valve of the invention is ideally suited for use in an air-flow measuring device, and preferably includes mans for releasably securing the valve to such a device.
  • the valve is made from a number of easily assembled and disassembled components thus facilitating cleaning.
  • the valve components preferably comprise plastics material or other suitable material to withstand regular sterilisation.
  • a device for measuring air-flow comprising:
  • an air-flow valve substantially as defined above, including at least one blade means adapted to rotate in response to a force directed through the air inlet;
  • one or more optical transducers adapted to monitor the movement of said blade means
  • processing means for determining a required parameter from the output(s) of said optical transducer(s);
  • the blade means is arranged to affect said optical transducers so as to interfere with or interrupt either an infra-red or a light beam.
  • said valve body includes a mouthpiece which is releasably connected to the valve body so that a variety of mouthpieces can be attached to the device.
  • valve is releasably attached to the device to facilitate cleaning or substitution of the valve.
  • FIG. 1A shows a top perspective view of a first arrangement of air-directing stator according to the present invention
  • FIG. 1B shows a bottom perspective view of the stator of FIG. 1A
  • FIGS. 2A and 2B show a top plan view and a bottom plan view of the first arrangement of air-directing stator, respectively;
  • FIGS. 3A and 3B show a top plan view and a bottom plan view of a second arrangement of air-directing stator, respectively;
  • FIG. 4A shows a sectional side view of the second arrangement of air-directing stator
  • FIG. 4B shows a sectional side view of the second arrangement of air-directing stator
  • FIGS. 5A, 5 B and 5 C show a first bottom perspective view, a second bottom perspective view and a top perspective view of a valve body, respectively;
  • FIGS. 5D and 5E show a top plan view and a bottom plan view of the valve body of FIG. 5 a;
  • FIG. 5F shows a rotor mountable in the valve body and held therein by a stator
  • FIG. 6A shows a sectional view of a mouthpiece for attachment to the valve housing
  • FIG. 6B shows a side view of the mouthpiece
  • FIG. 6C shows a top plan view of the mouthpiece of FIG. 6A
  • FIG. 7 shows a perspective view of a device for measuring air-flow
  • FIG. 8 shows a sectional side view of the device of FIG. 7;
  • FIG. 9 shows a top view of the device partly in cross-section
  • FIG. 10 is a schematic circuit digram of optical, processing and displaying elements of the device.
  • FIG. 11 is a top plan view of a third arrangement of stator having air-directing fins
  • FIG. 12 is a side sectional view of the stator of FIG. 11;
  • FIG. 13 is a perspective view of a valve insert
  • FIG. 14 is a cross-sectional elevation of the insert taken along lines X—X of FIG. 13;
  • FIG. 15 is a side perspective view of an air-flow meter having a transparent mouthpiece and incorporating the insert of FIG. 13 .
  • the air-flow valve of the invention comprises a first arrangement of stator 10 consisting of a hat-shaped body having a rim 12 , a riser 13 and an upper region 14 which is conical.
  • Air-directing apertures 15 are provided in the riser 13 .
  • a rotor bearing 16 is provided at the apex of the conical upper region 14 and comprises a screw adjuster 17 and spindle seat 18 .
  • FIGS. 1A, 1 B, 2 A and 2 B show more particularly the positioning of the apertures 15 in the first arrangement of stator 10 , the apertures 15 being equi-spaced around the periphery of the riser 13 .
  • the apertures 15 extend the height of the riser 13 and extend also towards the rim 12 , as shown in FIGS. 2A and 2B.
  • the apertures 15 are angled axially so as to efficiently direct air-flow.
  • Alternative forms of stator for example, where the apertures extend towards the rim by means of upstanding fins or flaps (FIGS. 11 and 12 ), will be described hereinafter.
  • a second arrangement of stator 20 has a hat-shaped body similar to that of the first stator 10 .
  • the stator 20 has a flattened rim 22 , a riser 23 and conical upper region 24 , as before.
  • the radial position of the riser 23 is relatively closer to the rim 22 and the conical upper region 24 accordingly has a shallower gradient.
  • Air-directing apertures 25 are provided about the periphery of the riser 23 and the apertures extend axially inwards to a greater extent than the apertures 15 illustrated with respect to the first arrangement of stator 10 .
  • FIGS. 4A and 4B show in cross-section the first and second arrangements of stator 10 , 20 , respectively, and illustrate the provision of the rotor bearing 16 , 26 depending along the central axis of the stator 10 , 20 from the apex of the conical region 14 , 24 .
  • the air-flow valve further comprises a substantially tubular body 30 having an open mouth 31 , including a land 32 , in which the stator 10 , 20 sits.
  • a cross member 33 is provided within the body for fixing a second rotor bearing 34 , again comprising a screw adjuster 35 and a spindle seat 36 .
  • a rotor 40 is held between the stator mounted bearing 16 , 26 and the second bearing 34 .
  • the bearings abut opposite ends of a spindle 42 on which a blade or blades 44 are mounted, as illustrated in FIG. 5 F.
  • a mouthpiece 50 (as shown in detail in FIGS.
  • valve body 30 which sits into the valve body 30 by way of a push fit connection.
  • the valve is adapted to be removable from an air-flow measurement device and to facilitate this the valve body 30 is provided with a pair of positioning flanges 37 extending radially therefrom and includes detent grooves 38 for co-operating with a fixing bead to allow snap fitting of the valve to a measuring device.
  • a pair of apertures 39 is provided in the valve body 30 to allow optical detection of the rotation of the rotor 40 .
  • the rotor 40 comprises a metal spindle 42 having tapered ends 46 (for low function interaction with the bearings) and a unitary rotor blade 44 which is glued, threaded or otherwise fixed to the spindle.
  • the preferred blade material is a thin sheet of rigid plastics material such as celluloid or the like. The low inertia of this construction allows the rotor 40 to be accelerated from zero to approximately 80,000 r.p.m in milliseconds and facilitates extremely sensitive and accurate air-flow measurements.
  • the rotor blade 44 can be integrally formed with its shaft 42 and can have self-lubricating bearings.
  • the blade 44 can be any convenient shape but the preferred shape is substantially rectangular.
  • the position of the rotor blade 44 is such that when the assembled valve is attached to a measuring device of the type described below, the blade 44 is located between an infra-red or light beam emitter and its corresponding detector.
  • the mouthpiece 50 consists of a conical or funnel-shaped portion 52 , shaped to correspond with the conical upper region 14 , 24 of a stator 10 , 20 , and has integrally formed therewith an air inlet 54 about which a test subject or patient places their lips to exhale air into the air-flow valve.
  • the inlet 54 may have an ovoid cross-sectional shape but a proportionally larger, circular aperture is preferred for use with weaker test subjects.
  • a rim 55 is provided to engage the open mouth 31 of the valve body 30 .
  • An annular flange 56 is positioned adjacent the rim 55 to facilitate a sealing engagement of the mouthpiece 50 to the valve body 30 . The distance between the flange 56 and the rim edge is selected with respect to the type of stator 10 , 20 used.
  • stator 10 the first arrangement of stator 10 is shown and the rim 55 of the mouthpiece 50 abuts against the stator rim 12 .
  • the mouthpiece rim 55 is extended, the corresponding height of the stator rim 12 can be reduced or eliminated altogether (as in the second stator arrangement).
  • the air-flow valve is constructed to be detachable from an air-flow measuring device, thus facilitating replacement or interchanging of an air-flow valve from an air-flow measuring device. Further, the air-flow valve is made of material which can be easily sterilised without damage and may be disassembled for thorough cleaning.
  • the stator 10 , 20 is inverted and one tapered end 46 of the rotor spindle 42 is positioned in the bearing seat 17 , 27 .
  • the valve body 30 is then positioned over the stator 10 , 20 and the free end of the spindle 42 is guided into the corresponding bearing seat 36 mounted in the cross member 33 of the valve body 30 .
  • the mouthpiece 50 is then placed over the conical region 14 , 24 of the stator 10 , 20 to secure the valve components in fixed relationship to one another. Adjustments to the rotor bearings 16 , 26 , 34 are then made to ensure minimal rotational friction on the rotor 40 .
  • FIGS. 7, 8 and 9 show an assembled apparatus for measuring respiratory performance.
  • the assembly comprises an air-flow valve, as hereinabove described, and a device 100 having a housing which is profiled to be a hand-held instrument to which the valve is releasably attached.
  • the housing includes a battery compartment 101 , a display 102 and a semi-circular recess 103 which includes a pair of securing beads 104 for engaging the corresponding detent grooves 28 in the valve body 30 .
  • the grooves 38 and beads 104 together with the positioning flanges 37 , which abut the housing, position the valve into the semi-circular recess 103 . This positively locates the valve body apertures 39 across an infra-red or light beam generated by the device 100 .
  • the device 100 is provided with a printed circuit board 105 which is powered from batteries 106 in the battery compartment 101 and generates an infra-red or light beam between optically-coupled semi-conductor elements 108 , 109 positioned so as to transmit and receive the beam through the apertures 39 provided in the valve body 30 .
  • Data processed by the circuit board 105 is presented on the display 102 .
  • a test subject blows or exhales into the mouthpiece 50 , the exhaled air is directed as indicated by the arrows in FIG. 9 .
  • the rotor 40 rotates under the influence of the directed air and interrupts the infra-red or light beam as it rotates. The number of interruptions to the beam is indicative of the speed of the rotor 40 .
  • the volume of air expelled by the subject is a function of the rotor speed and the duration for which the rotor is moving.
  • the circuitry mounted on the circuit board 105 measures the speed of the rotor 40 to calculate air-flow parameters as required.
  • the exhaled air As the exhaled air enters the air inlet 54 , it impinges the conical upper surface 14 , 24 of the stator 10 , 20 and is spread outwardly over that surface 14 , 24 as constrained by the corresponding inner profile 52 of the mouthpiece 50 .
  • a back-pressure develops as the exhaled air accumulates in a chamber defined between the stator 10 , 20 and the valve body 30 or mouthpiece rim 55 .
  • the air must substantially change direction from that imposed by the mouthpiece 50 and stator 10 , 20 constriction.
  • the air flows through apertures or slits 15 , 25 and is angularly deflected by the aperture profiles into a direction which is towards or perpendicular to the planar surface of the blade 44 .
  • FIG. 10 the electronic circuitry for use in the measuring device is shown schematically.
  • Power is provided from batteries via a push button switch which initially resets a microcontroller U 1 (PIC 16C 11SO20) and enables a counter.
  • Infra-red or visible light is emitted by a light emitting diode 108 (LED 1 ) and is received by an optical sensor element 109 (Q 1 ).
  • Interruptions to the light beam cause a pulse to be sent to the micro controller U 1 which counts the pulses.
  • the pulse count is compared against time, as measured using an oscillator which is controlled by a crystal Y 1 .
  • the air-flow parameters required for presentation on a liquid crystal display (LCD) 102 are pre-programmed into the micro controller U 1 .
  • LCD liquid crystal display
  • the peak flow of air exhaled by a subject is obtained.
  • the FEV 1 measurement is made.
  • the FEV 1 value and peak flow measurement are then displayed on the LCD 102 .
  • the measurements are flashed on the LCD 102 alternately and for a period after the operating switch has been released. This allows a physician or tester adequate time to record the measurements.
  • Appendix 1 attached herewith provides a list of component values and further details of the components used in the circuit.
  • a third arrangement of stator 210 as shown in FIGS. 11 and 12, comprises a hat-shaped body having a rim 212 , riser 213 and an upper conical region 214 , substantially identical to the first stator arrangement 10 .
  • Air-directing apertures 215 are provided as before, however, each aperture 215 is flanked by a fin 220 extending from the aperture towards to the rim 212 .
  • the fins 220 are preferably integrally formed with the stator 210 but may be glued or otherwise fixed to the riser 213 or apertures 215 .
  • the fins 220 may extend fully to the rim 212 .
  • the air-flow valve can include a fourth arrangement of stator comprising two parts.
  • the first part comprises a stator similar or identical to the first or second stator arrangements 10 , 20 .
  • the second part as illustrated in FIGS. 13 and 14, comprises a valve insert 250 which, in use, is placed over the stator 10 , 20 and fits into the chamber defined between the stator 10 , 20 and the valve body 30 or mouthpiece 50 .
  • the insert 250 comprises essentially a ring having a series of air-flow guides 252 arranged to correspond with the apertures 15 , 25 in the riser 13 , 23 of the stator 10 , 20 . These guides 252 act to assist the smooth transition in direction of the air-flow from the air-inlet 54 towards to the rotor blades 44 .
  • the guides 252 have a curved shape, shown in detail in FIG. 14, which cause incident air to sharply but smoothly change direction. Back-pressure in this arrangement is less than that encountered with the stators 10 , 20 , 210 alone.
  • This arrangement of air-flow valve, that is, with the insert 250 in place, is particularly effective for testing subjects where the incident air-flow rate is anticipated to be low.
  • FIG. 15 is a perspective view of an apparatus for measuring respiratory function 100 having a transparent mouthpiece 50 (for clarity) and incorporates an insert 250 of the type described above.
  • the air-flow valve of the invention thus provides a means of increasing the sensitivity of an apparatus for measuring respiratory performance by simply making maximum use of expired air. Re-direction of air-flow is employed in this way in order to reduce inefficiency of existing systems.
  • R1 1K 5% tolerance R2 33K 5% exact value will depend on characteristics of optical elements R3 47K 5%, exact value will depend on characteristics of optical elements R7 10K 5% tolerance R8 10K 5% tolerance R9 10K 5% tolerance R10 10K 5% tolerance R11 10K 5% tolerance R12 10K 5% tolerance C1 100 nF Ceramic C2 33 pF Ceramic, exact value to suit crystal used C3 33 pF Ceramic, exact value to suit crystal used Y1 4 MHz Crystal U1 PIC16C711-SO20 (XTSO) programmable microcontroller LED1 Infrared Emitting Diode Q1 Infrared Sensor Display Custom 24 segment Triplexed Display SW1 Push-to-make contact switch
  • Infrared emitting diode e.g. SEP9606.
  • the display character height 6 mm
  • the rms voltage ratio between a segment being on or off is 1.73.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Volume Flow (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Drying Of Semiconductors (AREA)
  • Measurement Of Radiation (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Indicating Or Recording The Presence, Absence, Or Direction Of Movement (AREA)
US09/268,005 1994-11-30 1999-03-15 Peak flow meter Expired - Fee Related US6314822B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9424230 1994-11-30
GB9424230A GB9424230D0 (en) 1994-11-30 1994-11-30 Peak flow meter

Related Parent Applications (2)

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PCT/GB1995/002793 Continuation-In-Part WO1996016598A1 (en) 1994-11-30 1995-11-29 Peak-flow meter
US08849647 Continuation-In-Part 1997-05-29

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US (1) US6314822B1 (ja)
EP (1) EP0794730B1 (ja)
JP (1) JPH10509891A (ja)
AT (1) ATE180151T1 (ja)
AU (1) AU3987495A (ja)
CA (1) CA2205841A1 (ja)
DE (1) DE69509787T2 (ja)
ES (1) ES2134504T3 (ja)
GB (2) GB9424230D0 (ja)
NZ (1) NZ296152A (ja)
WO (1) WO1996016598A1 (ja)

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US6467480B1 (en) * 1998-09-09 2002-10-22 Bernd Horst Meier Procedure and device for the movement and volume measurement of fluids and gases and device for the implementation of a respiration
CN100403032C (zh) * 2006-05-29 2008-07-16 东南大学 基于微机械技术的电容非热式流速传感器
US20080249429A1 (en) * 2007-03-29 2008-10-09 Vitalograph (Ireland) Limited Spirometers
US20080306352A1 (en) * 2004-03-26 2008-12-11 Healthcarelink Apparatus and System for Predictive Health Monitoring
US20100199758A1 (en) * 2009-02-11 2010-08-12 Ecolab Inc. Flow meter
WO2012038903A2 (en) * 2010-09-22 2012-03-29 Lior Gonnen Modular acoustic spirometer
US8166828B2 (en) 2010-08-06 2012-05-01 Ecolab USA, Inc. Fluid flow meter
CN102525476A (zh) * 2010-11-05 2012-07-04 谢达斌 可携式气喘检测装置及独立型可携式气喘检测装置
EP1689296B1 (en) * 2003-10-22 2013-02-13 MIR S.r.l. Disposable spirometer with plastic injection moulded turbine
US20170231525A1 (en) * 2014-08-19 2017-08-17 Wwws Uk Limited Spirometer
US9763626B2 (en) 2010-09-22 2017-09-19 Breathe.Me Ltd. Acoustic spirometer system
US10746576B1 (en) * 2019-05-30 2020-08-18 Seoul Industry Engineering Co., Ltd. Portable air flow meter fabricated using 3D printer
RU2788809C1 (ru) * 2022-08-03 2023-01-24 Сергей Александрович Линник Устройство и способ для измерения скорости вдоха у пациентов с бронхообструктивными заболеваниями

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CN105451641B (zh) * 2013-03-14 2018-10-23 M·祖贝尔·米尔扎 基于互联网的疾病监测系统(idms)

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ATE180151T1 (de) 1999-06-15
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EP0794730B1 (en) 1999-05-19
GB2295650A (en) 1996-06-05
JPH10509891A (ja) 1998-09-29
GB9524432D0 (en) 1996-01-31
WO1996016598A1 (en) 1996-06-06
EP0794730A1 (en) 1997-09-17
AU3987495A (en) 1996-06-19
NZ296152A (en) 1999-08-30
DE69509787D1 (de) 1999-06-24
GB9424230D0 (en) 1995-01-18
DE69509787T2 (de) 1999-12-02
CA2205841A1 (en) 1996-06-06

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