US5718680A - Catheter system with push rod for advancement of balloon along guidewire - Google Patents

Catheter system with push rod for advancement of balloon along guidewire Download PDF

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US5718680A
US5718680A US08/700,939 US70093996A US5718680A US 5718680 A US5718680 A US 5718680A US 70093996 A US70093996 A US 70093996A US 5718680 A US5718680 A US 5718680A
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Prior art keywords
guidewire
balloon
angioplasty balloon
abutment
passage
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US08/700,939
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Jeff L. Kraus
Michael J. Horzewski
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Danforth Biomedical Inc
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Danforth Biomedical Inc
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Assigned to SPECTRUM MANUFACTURING, INC., MEDSOURCE TRENTON LLC, PORTLYN, LLC, LAKE REGION MEDICAL, INC., MEDSOURCE TECHNOLOGIES, LLC, LAKE REGION MANUFACTURING, INC., THERMAT ACQUISITION, LLC, NOBLE-MET LLC, MEDSOURCE TECHNOLOGIES, NEWTON INC., UTI HOLDINGS, LLC, MEDSOURCE TECHNOLOGIES PITTSBURGH, INC. reassignment SPECTRUM MANUFACTURING, INC. RELEASE BY SECURED PARTY (SEE DOCUMENT FOR DETAILS). Assignors: UBS AG, STAMFORD BRANCH, AS COLLATERAL AGENT
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/0102Insertion or introduction using an inner stiffening member, e.g. stylet or push-rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/104Balloon catheters used for angioplasty
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M2025/0063Catheters; Hollow probes characterised by structural features having means, e.g. stylets, mandrils, rods or wires to reinforce or adjust temporarily the stiffness, column strength or pushability of catheters which are already inserted into the human body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M2025/0183Rapid exchange or monorail catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/107Balloon catheters with special features or adapted for special applications having a longitudinal slit in the balloon

Abstract

An elongated rod terminating in an abutment device with a lumen for passage of a guidewire is used to push an angioplasty balloon along the guidewire and through a vasculature to a location where treatment is needed. The balloon is fed by an inflation tube which remains independent of the guidewire and need not have axial rigidity. This combination of components permits one to exchange balloons without the need for a guidewire extending 100 cm or more outside the patient's body. Guidewire exchanges are also possible in cetain embodiments of the concept, and possibilities for perfusion are also presented. The guidewire passes through a tube inside the balloon which can also be used for perfusion of the patient's blood when the guidewire is withdrawn.

Description

This is a Division of application Ser. No. 08/277,878 filed Jul. 20, 1994, now U.S. Pat. No. 5,578,009.

This invention resides in the field of angioplasty, and relates in particular to catheters and catheter components used in performing angioplasty procedures.

BACKGROUND OF THE INVENTION

Angioplasty is a procedure widely used for the treatment of blocked arteries and has been developed to the point where it is effective for blockages varying considerably in density, size and location in the vasculature, and has also been used in combination with other procedures. With such a wide scope of applicability, a considerable amount of variation can be encountered in terms of the therapeutic needs for treating a blockage and any conditions associated with it, as well as the means of meeting those needs. For example, the ease of placing the balloon tip of the catheter at the desired location, the size and type of balloon needed, the need for other means of ablating the blockage or otherwise treating the vessel, can all vary widely, and it is frequently impossible to accurately predict each of these in advance of the procedure. As a result, the physician must often exchange a guidewire or balloon after it has been inserted.

Over-the-wire catheters are designed to permit these types of exchanges. Due to the distance that the catheter must be inserted inside the body to reach the site where treatment is to be performed, however, these catheters are generally about 135 cm or more in length. While drawing the catheter backward over the guidewire, of course, the physician must maintain a grip on the guidewire to hold its position. As a result, the guidewire will generally be at least twice as long as the catheter. Alternatively, a guidewire of shorter length, but one to which an extension can be attached, will be used. In either case, the procedure is awkward, the extra length or the extension interfering with the ease and speed of the exchange and of the procedure as a whole.

SUMMARY OF THE INVENTION

This invention resides in a balloon-tipped catheter system for angioplasty procedures which permits exchange of a balloon without removal of the guidewire and without requiring a guidewire of double or otherwise extraordinary length. With its unusual construction, the system also permits perfusion of blood through an angioplasty balloon from surrounding regions immediately adjacent to the balloon ends independently of whether the balloon is inflated.

The system consists of a combination of components, the primary components being:

(a) a guidewire;

(b) a balloon with a supply or inflation tube for inflation purposes and a through-passage, separate from the inflation tube, for the guidewire; and

(c) an elongated rod terminating in a sliding device to travel along either the guidewire, the inflation tube or both to abut the proximal end of the balloon or the proximal end of any short tubular extension at the proximal end of the balloon, the rod having sufficient axial rigidity that it can advance the sliding device through the vasculature to push the balloon along the guidewire.

The balloon will thus be inserted into the vasculature and advanced over the guidewire toward the point of the blockage by the sliding device which is in turn manipulated from outside the body by the elongated rod. When an exchange is needed, the balloon will be removed by pulling the inflation tube to draw the balloon back over the guidewire. The separation of the guidewire from the balloon inflation tube permits the two to be held separately outside the patient's body so that the guidewire can be gripped at a point close to the point of entry into the body while the balloon is being withdrawn. The rod which supports the sliding device is likewise independent of the guidewire outside the body. This allows the physician to advance the balloon the full distance of the guidewire while again gripping the guidewire close to its point of entry in the body. Since it can be held so close to the point of entry, the guidewire therefore need be only slightly longer than the length it penetrates the vasculature. In addition, the shaft profiles of the guidewire, the balloon inflation tube, and the push rod, can all be very small while still providing lumens of adequate size for inflation of the balloon and for the guidewire.

Embodiments of the invention in which only the guidewire passes through the sliding device are fully sufficient for procedures in which the balloon may be exchanged without disturbing the guidewire. In variations of these embodiments, the sliding device contains two lumens and the supporting rod contains a lumen as well. One lumen of the sliding device is specially configured to be advanced over the inflation line while the other lumen is a continuation of the supporting rod lumen. This enables a guidewire to be passed through the supporting rod and sliding device into the balloon through-passage. Longitudinal slits in both the inflation line lumen and the supporting rod lumen then permit the guidewire to be separated from the rod outside the patient's body, and detached from the inflation line, once again permitting the guidewire to be gripped close to the body.

Blood perfusion through the balloon, when desired, is achieved by simply withdrawing the guidewire from the balloon a sufficient distance to clear the opening to the guidewire through-passage at the proximal end of the balloon. Blood then flows through the open through-passage, entering the passage at one end of the balloon and leaving it at the other. This provides a short perfusion path which is at most slightly longer than the length of the balloon.

These and other features and advantages of the invention will be apparent from the description which follows.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 is a planar view of the components of one embodiment of the invention.

FIG. 2 is a longitudinal cross section of the balloon component of FIG. 1.

FIG. 3 is a perspective view of components of a second embodiment of the invention.

FIG. 4 is a cross section taken along the line 4--4 of FIG. 3.

FIG. 5 is an enlarged detail view of two of the components of the embodiment of FIGS. 3 and 4.

FIG. 6 is a perspective view of components of a third embodiment of the invention.

FIG. 7 is a cross section taken along the line 7--7 of FIG. 6.

FIG. 8 is another perspective view of the embodiment shown in FIG. 6, but with the guidewire retracted.

FIG. 9 is a perspective view of components of a third embodiment of the invention.

FIG. 10 is a cross section taken along the line 10--10 of FIG. 9.

DETAILED DESCRIPTION OF THE INVENTION AND PREFERRED EMBODIMENTS

While this invention is generic in scope, it will be best understood by a detailed discussion of specific embodiments.

FIG. 1 depicts portions of the three primary components of one system in accordance with the invention. The components are a guidewire 11, an inflatable angioplasty balloon 12 joined to flexible tubing 13 serving as an inflation/deflation line, and a sliding device 14 (referred to herein for convenience as a "bumper") joined to the distal end of a elongated supporting rod 15 (referred to herein for convenience as a "push rod"). The distal end of the guidewire is toward the upper right corner of the Figure. Accordingly, the balloon 12 has a distal end 16 and a proximal end 17, and the inflation/deflation line 13 feeds the balloon at the proximal end 17 of the balloon. The bumper 14 in this embodiment is in the form of a cylinder with a distal end 18 and a proximal end 19, the distal end 18 of the cylinder abutting the proximal end 17 of the balloon when the bumper is advanced, and the push rod 15 joined to the bumper at its proximal end 19.

The bumper 14 in this embodiment contains a single lumen extending through it in the longitudinal direction to permit passage of the guidewire 11. The lumen provides sufficient clearance to permit the bumper to be slid easily over the guidewire. The push rod 15, like the guidewire itself, is flexible enough to permit it to conform to the curves and directional changes encountered in the vasculature yet with sufficient axial rigidity (or to use a term which is commonly used in this art, "pushability") to allow it to be advanced forward from outside the body without kinking or bending back over itself.

The interior of the balloon is shown in the cross section view of FIG. 2, in which the distal end 16 of the balloon is at the right side and the proximal end 17 is at the left. The balloon contains an internal tubular member 21 which spans the balloon interior from the proximal end to the distal end and provides a through-passage for the guidewire 11. The tubular member 21 is also sufficiently stiff to maintain axial elongation of the balloon, i.e., to prevent the balloon from collapsing back along its longitudinal axis as the balloon is being pushed from its proximal end 17 through the vasculature and particularly through an arterial blockage where high resistance may be encountered.

The sheath 22 of the balloon is sealed around both ends of the internal tubular member 21 to form an inflatable cavity 23 which encircles the tubular member. This inflatable cavity 23 is fed by the inflation/deflation line 13 at a port 24 which is adjacent to the internal tubular member 21. The inflation/deflation port 24 is offset from the internal tubular member 21 to leave sufficient area 25 at the proximal end of the balloon surrounding the opening of the tubular member for contact by the distal end 18 of the bumper (FIG. 1) without interfering with or damaging the inflation/deflation line 13. alternatively, the inner tubular member 21 may be connected to a multilumen fitting at the proximal end of the balloon to form a similar configuration.

A further structure within the scope of this invention is shown in FIGS. 3, 4 and 5. The components of this structure are designed to permit exchange of one guidewire for another without removal of the balloon, and also to permit perfusion of a functional fluid through the balloon to the region of the vasculature at the distal end of the balloon, by removing the guidewire and perfusing the fluid through the guidewire lumen. The components shown in FIG. 3 include a balloon 31 with an inflation/deflation line 32 leading to the inflatable cavity inside the balloon, a bumper 33 at the distal end of a push rod 34, and a guidewire 29 passing through the push rod, the bumper and the balloon, with the distal tip 31 of the guidewire emerging from the distal end of the balloon. These components have the same characteristics as the similarly-named components in the embodiment shown in FIG. 1.

FIG. 4 is a cross section taken at the line 4--4 of FIG. 3, and FIG. 5 is an enlarged segment view of the guidewire 29 and the push rod 34.

As seen in FIG. 4, the bumper 33 contains a lumen 35 as in the embodiment of FIG. 1, except that the lumen in this case is designed for passage of the inflation/deflation line 32 rather than the guidewire. Like the lumen in the bumper of FIG. 1, the inflation/deflation line lumen 35 of FIGS. 3 and 4 extends only through the bumper itself.

A second lumen 36 extends through both the bumper 33 and the push rod 34. This lumen is used for passage of the guidewire. This guidewire lumen 36 contains a longitudinal slit 37 through which the guidewire can be removed or inserted. The slit 37 is shown in an open condition in FIG. 5. The material from which the push rod 34 is made is sufficiently resilient to permit the slit to be stretched open but to close the slit once the stretching force is removed. The slit 37 may extend the full combined length of the push rod 34 and the bumper 33. Alternatively, the slit may extend only the length of the push rod and either not extend into the bumper or only partially so.

The balloon 31 is similar to the balloon of the embodiment of FIG. 1, with an identical internal tubular member 41 (shown in dashed lines in FIG. 3) to maintain elongation of the balloon and to provide a through-passage for the guidewire, and the same relative positions of the proximal opening 38 of the tubular member and the point of entry of the inflation/deflation lumen 32. When the guidewire is in place, it thus passes through the guidewire lumen 36 in the push rod and the internal tubular member 41 in the balloon.

As seen in FIG. 4, the shorter lumen 35 for the inflation/deflation line 32, and the inflation/deflation line itself have specially shaped cross sections to prevent the rotation of one relative to the other and to thereby maintain alignment between the guidewire lumen 36 in the push rod and the internal tubular member in the balloon. The cross sections shown in the drawing are D-shaped. Any non-circular shape will suffice, however.

The components of the system shown in FIGS. 3, 4 and 5 may be used in a variety of procedures. For example, the balloon 31 and the bumper 33 can be assembled outside the patient's body by threading the inflation/deflation line 32 backwards through the short bumper lumen 35. The guidewire is then inserted into the vasculature past the region where treatment is desired, using conventional techniques of guidewire placement, and the combined balloon and bumper are then threaded over the guidewire and advanced into the vasculature by the push rod 34. The operator can maintain a grip on the proximal end of the guidewire by forcing the push rod slit laterally over the guidewire in stages at a point distal to the operator's grip but still outside the patient's body.

If it is then necessary to exchange the balloon, this is done without removal of the guidewire, by pulling on the inflation/deflation line 32 to withdraw the balloon while also pulling on the push rod 34 to withdraw the push rod and bumper 33. Withdrawing the balloon by this procedure is the same as withdrawing the balloon in the assembly shown in FIG. 1, since the inflation/deflation line is separated from and independent of the guidewire. Withdrawing the push rod 34 without withdrawing the guidewire, however, and without requiring a second length of guidewire extending outside the patient's body, is accomplished by laterally pulling the push rod away from (i.e., off of) the guidewire at a point close to the point of entry into the body, as shown in FIG. 5. The guidewire thus passes through the slit 37 in the push rod to separate it from the push rod. In this manner, the operator can maintain a grip on the guidewire close to the patient's body as in the embodiment of FIG. 1. Once the balloon and the bumper are disengaged entirely from the guidewire, a new balloon can be assembled to the bumper in the same manner as the first balloon, and then advanced along the guidewire, again in the same manner.

Exchange of the guidewire without removal of the balloon can also be accomplished, simply by removing the existing guidewire through the guidewire lumen 35 without removing the push rod 34 and without the need for passing the guidewire through the slit 37, and replacing the withdrawn guidewire with a new guidewire. The guidewire lumen 35 in the push rod and the internal tubular member opening 38 are held in alignment during this procedure by the fixed orientation of the push rod relative to the balloon, which is in turn maintained by the complementary non-circular cross sections of the bumper lumen 35 and the inflation/deflation the 32.

The components as shown may also be used for perfusion of a region of the vasculature with a functional fluid from outside the patient's body. The functional fluid may for example be a drug or a solution of a contrast agent for imaging purposes, and will pass through the vasculature and out the distal end of the balloon. The guidewire lumen may be used as a perfusion lumen. This is easily done by withdrawing the guidewire, leaving the balloon and push rod in place. The guidewire lumen 36 and the internal tubular member in the balloon are then available for the passage of the perfusion fluid. Alignment of these passages is maintained by the non-circular cross sections as indicated above. In addition, the contact surfaces at the distal end 39 of the bumper and the proximal end 40 of the balloon surrounding the internal tubular member opening 38 are both flat, to provide full contact around the circumference of the passage and minimal opportunity for leakage outward in the lateral direction.

A third variation on the structures discussed above is that shown in FIGS. 6 and 7. The components of this structure include a balloon 51, an inflation/deflation line 52 leading to the cavity inside the balloon, a bumper 53 at the distal end of a push rod 54, and a guidewire 55 passing through the bumper 53 and an internal tubular member 56, with the distal end 57 of the guidewire protruding from the distal end of the balloon 51. In this structure as in the structure of FIG. 3, there are two lumens through the bumper, one 61 extending only through the bumper itself and the other 62 extending through both the bumper and the push rod. This structure differs, however, in that the inflation/deflation line 52 of noncircular cross-section passes through the lumen 62 which extends the length of the push rod, and the circular cross-section guidewire 55 passes through the lumen 61 which extends only through the bumper. The lumen 62 through the push rod is of a non-circular cross section to match that of the inflation/deflation line 52.

The use of the system of FIGS. 6 and 7 is similar to that of the system of FIGS. 3, 4 and 5 for advancing a balloon along a guidewire and removing a balloon and replacing it with another balloon, without the need for a long guidewire. The structure of FIGS. 6 and 7 is not suitable for guidewire exchange without removing the push rod and bumper. It is particularly well adapted, however, for permitting passage of blood across the region of treatment during an angioplasty procedure. This is accomplished, as shown in FIG. 8, by withdrawing the bumper 53 a short distance to expose the proximal end 65 of the balloon, and withdrawing the guidewire 55 far enough to clear the internal tubular member 56 entirely and thereby permit the surrounding blood free access to the internal tubular member through the opening 66 at the proximal end of the tubular member.

The gap 67 between the distal end of the bumper 53 and the proximal opening 66 of the tubular member is not critical and may be less than 15 cm. The guidewire may be withdrawn to the point that its distal end 57 is inside the bumper. This is preferred for a guidewire with a curved tip if the guidewire is to be eventually reinserted through the balloon. For angioplasty procedures where a guide catheter surrounding the functional catheter is used, the bumper 53 and guidewire tip 57 are preferably withdrawn to a position just inside the guide catheter. Radiopaque marker bands 63, 64 aid in the visualization of the position of the bumper during its withdrawal. In any event, with the internal tubular member 56 open and its proximal opening 66 exposed, the patient's blood can enter the tubular member at the proximal opening, pass through the tubular member, and leave to reenter the blood stream at the distal end of the balloon. The path of blood flow is indicated by the arrows 68, 69.

A fourth variation is shown in FIGS. 9 and 10. Here the bumper and the pushrod are combined to form a single continuous dual-lumen rod 71, with a radiopaque marker band 77 at its distal tip. One of the two lumens 72 receives the inflation/deflation line 73, and both this lumen and the inflation/deflation line are of a non-circular cross section. The other lumen 74 receives the guidewire 75. Both the rod 71 and the guidewire 75 may be withdrawn a short distance to expose the internal tubular member 76 of the balloon for blood perfusion, as in the system of FIGS. 7 and 8. In this system, however, both lumens 72, 74 are of sufficient length to extend outside the patient's body while the balloon remains fully inserted. This permits the operator to perform a guidewire exchange without removing the balloon, simply by leaving the rod 71 in place (abutting the proximal end of the balloon, rather than separated from the balloon by as small gap as shown in FIG. 9), withdrawing the guidewire through the rod, and inserting the new guidewire back through the rod in place of the first guidewire.

The components in these various embodiments of the invention may be made of a variety of materials, as are the components of catheters and guidewires of the prior art. Likewise, the dimensions of the various components may vary, and are not strictly critical to the invention. In most applications, the bumper will be a cylinder of from about 0.5 cm to about 35 cm in length, and preferably from about 15 cm to about 30 cm in length. Likewise, the balloon, including its proximal and distal extremities, will generally be less than about 6 cm in length, and most often from about 3 cm to about 6 cm in length, the non-tapering central portion of the balloon being from about 2 cm to about 4 cm in length. The length of the push rod will most often be at least about 100 cm, and preferably at least about 120 cm.

The materials of construction may vary widely, and materials conventionally used or known or disclosed for use in catheters may be used here as well. Prime examples of materials for the various components are high density polyethylene, polyurethane, polyimide, hypotube (alloys of stainless steel or nickel and titanium), polytetrafluoroethylene and related materials known as Teflon, and composites of these materials, although any readily formable or extrudable material from which a shaft with dimensions and lumens of the requisite precision can be made may be used.

As one example of a typical construction for the components shown in FIG. 1, the balloon may be a polyethylene balloon 3.0 mm in expanded diameter, the inflation/deflation line may be polyimide with an internal diameter of 0.016 inch (0.041 cm) and an outer diameter of 0.018 inch (0.046 cm), the push rod may be steel coated with Teflon (polytetrafluoroethylene) with a diameter of 0.017 inch (0.043 cm), the bumper may be 25 cm in length with a guidewire lumen of 0.014 inch (0.036 cm) in diameter.

The foregoing is offered primarily for purposes of illustration. It will be readily apparent to those skilled in the art that the materials, dimensions, procedural steps and other parameters of the system described herein may be further modified or substituted in various ways without departing from the spirit and scope of the invention.

Claims (8)

What is claimed is:
1. A method of placing an angioplasty balloon at a selected location in a vasculature, said method comprising:
(a) advancing a guidewire through said vasculature until the distal tip of said guidewire is at least as far into said vasculature as said selected location, leaving a proximal segment of said guidewire outside said vasculature;
(b) placing an angioplasty balloon onto said guidewire, said angioplasty balloon having an inflatable cavity fed by an external tubular member and containing an internal tubular member forming an axial through-passage that is independent of said inflatable cavity, by placing said axial through-passage over said proximal segment;
(c) placing an abutment means onto said proximal segment proximal to said angioplasty balloon, said abutment means adapted to abut the proximal end of said balloon and to slide along said guidewire; and
(d) pushing said abutment means along said guidewire, thereby advancing said angioplasty balloon to said selected location.
2. A method in accordance with claim 1 in which said angioplasty balloon is a maximum of about 6 cm in length.
3. A method in accordance with claim 1 in which said abutment means comprises a cylinder of from about 0.5 cm to about 35 cm in length with a lumen extending therethrough to receive said guidewire, and an elongate rod.
4. A method in accordance with claim 3 in which said cylinder contains a slit running the length of said lumen, and step (c) comprises inserting said proximal segment of said guidewire through said slit.
5. A method for placing an angioplasty balloon and guidewire into a vasculature and exchanging said guidewires without removing said angioplasty balloon from said vasculature, said method comprising:
(a) advancing a first guidewire into said vasculature;
(b) placing an angioplasty balloon having an axial through-passage and an elongated inflation tube which is not in communication with said through-passage onto said first guidewire by placing said through-passage over the proximal end of said first guidewire and pushing said angioplasty balloon along said first guidewire with an elongated abutment rod, with said first guidewire passing through a lumen extending the length of said abutment rod, said abutment rod configured to maintain alignment of said lumen with said through-passage;
(b) withdrawing said first guidewire from said angioplasty balloon and said abutment rod while retaining said angioplasty balloon and said abutment rod in said vasculature; and
(c) inserting a second guidewire into said vasculature through said lumen in said abutment rod and through said through-passage in said angioplasty balloon.
6. A method of performing angioplasty on a region of treatment in a vasculature while permitting the passage of blood across said region of treatment, said method comprising:
(a) advancing a guidewire through said vasculature until the distal tip of said guidewire passes through said region of treatment;
(b) placing an angioplasty balloon having an axial through-passage and an inflation tube onto said guidewire by inserting a proximal end of said guidewire through said axial through-passage;
(c) advancing said angioplasty balloon over said guidewire to said region of treatment by passing said guidewire through an abutment tube through which said inflation tube also passes and advancing said abutment tube along said guidewire;
(d) when said angioplasty balloon is within said region of treatment, proximally retracting said abutment tube over said inflation tube and withdrawing said guidewire from said axial through-passage, thereby opening said through-passage for blood flow; and
(e) inflating said angioplasty balloon to treat said stenosis.
7. A method in accordance with claim 6 in which said abutment tube is at least about 100 cm in length, said inflation tube passes through the full length of said abutment tube, and said guidewire passes through a distal end of said abutment tube of less than about 35 cm in length.
8. A method in accordance with claim 6 in which said abutment tube is at least about 100 cm in length, and both said inflation tube and said guidewire pass through the full length of said abutment tube.
US08/700,939 1994-07-20 1996-08-21 Catheter system with push rod for advancement of balloon along guidewire Expired - Lifetime US5718680A (en)

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Cited By (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5916195A (en) * 1998-02-04 1999-06-29 Argomed Ltd. Internal catheter
WO2000004942A1 (en) * 1998-07-21 2000-02-03 Heartport, Inc. Multi-lumen catheters and methods of use and manufacture
WO2001066178A1 (en) * 2000-03-06 2001-09-13 Boston Scientific Limited Rapid exchange catheter with detachable hood
US6299595B1 (en) 1999-12-17 2001-10-09 Advanced Cardiovascular Systems, Inc. Catheters having rapid-exchange and over-the-wire operating modes
US6394995B1 (en) 1998-05-15 2002-05-28 X Technologies Inc. Enhanced balloon dilatation system
US6447501B1 (en) 1998-05-15 2002-09-10 X Technologies Inc. Enhanced stent delivery system
US20030125761A1 (en) * 2001-05-08 2003-07-03 Meens Hendrik Jozef Maria Balloon catheter
US20030195546A1 (en) * 1998-05-15 2003-10-16 Solar Ronald J. Enhanced catheter with alignment means
US20030199826A1 (en) * 1996-09-13 2003-10-23 Scimed Life Systems, Inc. Multi-size convertible catheter
US6652485B1 (en) * 2000-05-31 2003-11-25 Advanced Cardiovascular Systems, Inc. Balloon shoulder designs
US20030233043A1 (en) * 1996-09-13 2003-12-18 Scimed Life Systems, Inc. Guide wire insertion and re-insertion tools and methods of use
US20040039409A1 (en) * 2002-08-23 2004-02-26 Noel Coyle Convertible balloon catheter and manufacture thereof
US20040059369A1 (en) * 2002-09-20 2004-03-25 Niall Duffy Catheter and guide wire exchange system
US20040059291A1 (en) * 2002-09-20 2004-03-25 Mcdonnell Paula Catheter with improved transition section
US6716252B2 (en) 2000-06-30 2004-04-06 Wit Ip Corporation Prostatic stent with localized tissue engaging anchoring means and methods for inhibiting obstruction of the prostatic urethra
US20040106852A1 (en) * 1996-09-13 2004-06-03 Boston Scientific Corporation Guidewire and catheter locking device and method
US6746442B2 (en) 1996-09-13 2004-06-08 Boston Scientific Corporation Single operator exchange biliary catheter
US20040122363A1 (en) * 2002-09-20 2004-06-24 Richard Gribbons Catheter and guide wire exchange system with improved proximal shaft and transition section
US6780199B2 (en) 1998-05-15 2004-08-24 Advanced Cardiovascular Systems, Inc. Enhanced stent delivery system
US20040176790A1 (en) * 2003-03-03 2004-09-09 Medtronic Ave, Inc. Single lumen catheter shaft for a balloon catheter
US20040193139A1 (en) * 2003-01-17 2004-09-30 Armstrong Joseph R. Puncturable catheter
US6800065B2 (en) 2002-04-04 2004-10-05 Medtronic Ave, Inc. Catheter and guide wire exchange system
US20040204736A1 (en) * 2003-04-11 2004-10-14 Medtronic Ave, Inc. Catheter with a convertible proximal catheter shaft
EP1470834A1 (en) * 2003-04-24 2004-10-27 Medtronic Vascular, Inc. Catheter with detached proximal inflation and guidewire shafts
US20040260329A1 (en) * 2003-06-19 2004-12-23 Richard Gribbons Catheter and guide wire exchange system with decoupled guide member
US20050021004A1 (en) * 2003-01-17 2005-01-27 Cully Edward H. Puncturing tool for puncturing catheter shafts
US20050070880A1 (en) * 2003-09-26 2005-03-31 Medtronic Vascular, Inc. Transition section for a catheter
US20050070881A1 (en) * 2003-09-26 2005-03-31 Richard Gribbons Transition section for a catheter
US20050070879A1 (en) * 2003-09-26 2005-03-31 Medtronic Vascular, Inc Transition section for a catheter
US20050107819A1 (en) * 2003-11-14 2005-05-19 Medtronic Vascular, Inc. Catheter with a sectional guidewire shaft
US20050113803A1 (en) * 2003-11-24 2005-05-26 Medtronic Vascular, Inc. Apparatus and method for wire exchange
US20050137526A1 (en) * 2003-12-17 2005-06-23 Fidelis Machado Balloon catheter with positioning pocket
US20050148820A1 (en) * 2003-02-19 2005-07-07 Boston Scientific Scimed, Inc. Guidewire locking device and method
US20050212899A1 (en) * 2004-03-24 2005-09-29 Clarke Cyrus B Algorithms and methods for determining laser beam process direction position errors from data stored on a printhead
US6953431B2 (en) 2002-04-11 2005-10-11 University Of South Florida Eccentric dilation balloons for use with endoscopes
US20050240193A1 (en) * 2003-09-03 2005-10-27 Kyphon Inc. Devices for creating voids in interior body regions and related methods
US20060064074A1 (en) * 2004-09-21 2006-03-23 Scimed Life Systems, Inc. Rapid exchange catheters having a sealed guidewire lumen and methods of making the same
US20060173438A1 (en) * 2005-01-28 2006-08-03 Boston Scientific Scimed, Inc. Universal utility board for use with medical devices and methods of use
US20070049899A1 (en) * 2002-07-22 2007-03-01 Chambers Technology, Llc Catheter with flexible tip and shape retention
US20080058839A1 (en) * 2006-02-07 2008-03-06 Nobles Anthony A Reverse tapered guidewire and method of use
US20090062769A1 (en) * 2007-04-13 2009-03-05 Boston Scientific Scimed, Inc. Rapid exchange catheter converter
US20090198219A1 (en) * 2003-01-17 2009-08-06 Campbell Carey V Catheter Assembly
US20100081878A1 (en) * 2008-05-19 2010-04-01 Boston Scientific Scimed, Inc. Integrated Locking Device With Active Sealing
US7892201B1 (en) * 1999-08-27 2011-02-22 Gore Enterprise Holdings, Inc. Balloon catheter and method of mounting same
US8343041B2 (en) 2008-05-19 2013-01-01 Boston Scientific Scimed, Inc. Integrated locking device with passive sealing
US8372000B2 (en) 2007-01-03 2013-02-12 Boston Scientific Scimed, Inc. Method and apparatus for biliary access and stone retrieval
US8480570B2 (en) 2007-02-12 2013-07-09 Boston Scientific Scimed, Inc. Endoscope cap
US8979884B2 (en) 2009-12-15 2015-03-17 Cornell University Method and apparatus for stabilizing, straightening, expanding and/or flattening the side wall of a body lumen and/or body cavity so as to provide increased visualization of the same and/or increased access to the same, and/or for stabilizing instruments relative to the same
WO2016106224A1 (en) * 2014-12-22 2016-06-30 Heuser Richard R Device for treating vascular occlusion
US9986893B2 (en) 2009-12-15 2018-06-05 Cornell University Method and apparatus for manipulating the side wall of a body lumen or body cavity so as to provide increased visualization of the same and/or increased access to the same, and/or for stabilizing instruments relative to the same
US10149601B2 (en) 2009-12-15 2018-12-11 Lumendi Ltd. Method and apparatus for manipulating the side wall of a body lumen or body cavity so as to provide increased visualization of the same and/or increased access to the same, and/or for stabilizing instruments relative to the same

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5578009A (en) * 1994-07-20 1996-11-26 Danforth Biomedical Incorporated Catheter system with push rod for advancement of balloon along guidewire
US5882334A (en) * 1995-12-04 1999-03-16 Target Therapeutics, Inc. Balloon/delivery catheter assembly with adjustable balloon positioning
CA2192520A1 (en) 1996-03-05 1997-09-05 Ian M. Penn Expandable stent and method for delivery of same
CA2248718A1 (en) 1996-03-05 1997-09-12 Divysio Solutions Ulc. Expandable stent and method for delivery of same
US6796997B1 (en) 1996-03-05 2004-09-28 Evysio Medical Devices Ulc Expandable stent
DE69723137D1 (en) * 1996-03-18 2003-08-07 Hiroaki Ashiya Catheteranordnung
US6645138B2 (en) 1997-09-12 2003-11-11 Uromedica, Inc. Adjustable implantable genitourinary device
US6045498A (en) 1997-06-12 2000-04-04 Uromedica, Inc. Method for adjustably restricting a body lumen
US7364540B1 (en) * 1997-06-12 2008-04-29 Uromedica, Inc. Implantable device and method for adjustably restricting a body lumen
US6248100B1 (en) 1997-08-14 2001-06-19 Scimed Life Systems, Inc. Drainage catheter delivery system
US5921952A (en) 1997-08-14 1999-07-13 Boston Scientific Corporation Drainage catheter delivery system
US6592548B2 (en) 1997-09-18 2003-07-15 Iowa-India Investments Company Limited Of Douglas Delivery mechanism for balloons, drugs, stents and other physical/mechanical agents and method of use
US6056722A (en) 1997-09-18 2000-05-02 Iowa-India Investments Company Limited Of Douglas Delivery mechanism for balloons, drugs, stents and other physical/mechanical agents and methods of use
US20030233068A1 (en) * 1997-09-18 2003-12-18 Swaminathan Jayaraman Delivery mechanism for balloons, drugs, stents and other physical/mechanical agents and method of use
US6186999B1 (en) * 1998-08-27 2001-02-13 The Cleveland Clinic Foundation Rigid clampable cannula
DE60041917D1 (en) 1999-04-30 2009-05-14 Uromedica Inc Treatmen t of stress urinary incontinence
US6419624B1 (en) * 1999-10-11 2002-07-16 Uromedica, Inc. Apparatus and method for inserting an adjustable implantable genitourinary device
US6579224B1 (en) * 1999-10-11 2003-06-17 Uromedica, Inc. Apparatus and method for inserting an adjustable implantable genitourinary device
CA2398801C (en) * 2000-02-11 2007-12-04 Novo Rps Ulc Stent delivery system and method of use
US7238168B2 (en) * 2000-06-02 2007-07-03 Avantec Vascular Corporation Exchangeable catheter
US6475184B1 (en) 2000-06-14 2002-11-05 Scimed Life Systems, Inc. Catheter shaft
US6602226B1 (en) * 2000-10-12 2003-08-05 Scimed Life Systems, Inc. Low-profile stent delivery system and apparatus
US20030207659A1 (en) * 2000-11-03 2003-11-06 3M Innovative Properties Company Abrasive product and method of making and using the same
JP4259862B2 (en) * 2000-12-15 2009-04-30 シュコフ、ジョージ・エー Endoscopic prosthesis guidance system
CA2432028C (en) * 2000-12-15 2009-06-23 Donald R. Ricci Endovascular prosthesis delivery system
US6706055B2 (en) 2001-04-03 2004-03-16 Medtronic Ave Inc. Guidewire apparatus for temporary distal embolic protection
US6716223B2 (en) 2001-11-09 2004-04-06 Micrus Corporation Reloadable sheath for catheter system for deploying vasoocclusive devices
US10258340B2 (en) * 2001-11-09 2019-04-16 DePuy Synthes Products, Inc. Reloadable sheath for catheter system for deploying vasoocclusive devices
AT384488T (en) 2001-11-09 2008-02-15 Rubicon Medical Inc Stent-deposit device with embolic protection
US7166120B2 (en) * 2002-07-12 2007-01-23 Ev3 Inc. Catheter with occluding cuff
US6802806B2 (en) 2002-09-23 2004-10-12 Cleveland Clinic Foundation Apparatus for use with an inflow cannula of ventricular assist device
US7300415B2 (en) * 2002-12-20 2007-11-27 Advanced Cardiovascular Systems, Inc. Balloon catheter having an external guidewire
US7699865B2 (en) 2003-09-12 2010-04-20 Rubicon Medical, Inc. Actuating constraining mechanism
US8535344B2 (en) 2003-09-12 2013-09-17 Rubicon Medical, Inc. Methods, systems, and devices for providing embolic protection and removing embolic material
US20100261951A1 (en) * 2004-02-23 2010-10-14 Uromedica, Inc. Method and apparatus for an adjustable implantable continence device
US7824358B2 (en) * 2004-07-22 2010-11-02 Thoratec Corporation Heart pump connector
US7699862B2 (en) * 2005-01-25 2010-04-20 Micrus Corporation Resheathing tool
WO2006091786A1 (en) * 2005-02-23 2006-08-31 Uromedica, Inc. Method and apparatus for an adjustable implantable continence device
JP4648785B2 (en) * 2005-07-20 2011-03-09 Hoya株式会社 Indwelling balloon catheter for an endoscope
US20070043389A1 (en) * 2005-08-05 2007-02-22 Shintech, Llc System for treating chronic total occlusion caused by lower extremity arterial disease
JP4772446B2 (en) * 2005-09-30 2011-09-14 オリンパスメディカルシステムズ株式会社 Endoscope insertion aid and endoscope apparatus
US8048032B2 (en) * 2006-05-03 2011-11-01 Vascular Solutions, Inc. Coaxial guide catheter for interventional cardiology procedures
US7871396B2 (en) 2006-10-30 2011-01-18 Boston Scientific Scimed, Inc. Bifurcation catheter assembly and method
US8070694B2 (en) 2008-07-14 2011-12-06 Medtronic Vascular, Inc. Fiber based medical devices and aspiration catheters
WO2010077359A1 (en) 2008-12-30 2010-07-08 Mitchell Hardenbrook Expandable interbody implant and method
US8753303B2 (en) 2009-09-25 2014-06-17 Boston Scientific Scimed, Inc. Delivery system having stent locking structure
US9339631B2 (en) 2009-09-25 2016-05-17 Boston Scientific Scimed, Inc. Locking mechanism for a medical device
US9408733B2 (en) 2009-12-30 2016-08-09 Michael Devon Amos Rotatable connection between a tubular member and an elongate wire of a catheter
US9265637B2 (en) 2010-11-19 2016-02-23 Boston Scientific Scimed, Inc. Rapid exchange stent delivery system
US9623213B2 (en) * 2013-03-15 2017-04-18 Acclarent, Inc. Uncinate process support for ethmoid infundibulum illumination
US9615959B2 (en) 2013-03-15 2017-04-11 Acclarent, Inc. Uncinate process support for ethmoid infundibulum illumination
US9820761B2 (en) 2014-03-21 2017-11-21 Route 92 Medical, Inc. Rapid aspiration thrombectomy system and method
US9265512B2 (en) 2013-12-23 2016-02-23 Silk Road Medical, Inc. Transcarotid neurovascular catheter

Citations (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4517979A (en) * 1983-07-14 1985-05-21 Cordis Corporation Detachable balloon catheter
US4545367A (en) * 1982-07-16 1985-10-08 Cordis Corporation Detachable balloon catheter and method of use
US4771777A (en) * 1987-01-06 1988-09-20 Advanced Cardiovascular Systems, Inc. Perfusion type balloon dilatation catheter, apparatus and method
US4988356A (en) * 1987-02-27 1991-01-29 C. R. Bard, Inc. Catheter and guidewire exchange system
US5002556A (en) * 1986-11-29 1991-03-26 Terumo Kabushiki Kaisha Balloon catheter assembly
US5024658A (en) * 1988-06-13 1991-06-18 Kozlov Vladimir S Method and device for the diagnosis and treatment of nasal diseases
US5171222A (en) * 1988-03-10 1992-12-15 Scimed Life Systems, Inc. Interlocking peel-away dilation catheter
US5181921A (en) * 1990-05-25 1993-01-26 Kaken Co., Ltd. Detachable balloon with two self-sealing valves
US5205822A (en) * 1991-06-10 1993-04-27 Cordis Corporation Replaceable dilatation catheter
US5222970A (en) * 1991-09-06 1993-06-29 William A. Cook Australia Pty. Ltd. Method of and system for mounting a vascular occlusion balloon on a delivery catheter
US5267958A (en) * 1992-03-30 1993-12-07 Medtronic, Inc. Exchange catheter having exterior guide wire loops
US5425714A (en) * 1994-03-15 1995-06-20 Cordis Corporation Perfusion catheter with moving body
US5439445A (en) * 1992-08-07 1995-08-08 Boston Scientific Corporation Support catheter assembly
US5536250A (en) * 1994-04-01 1996-07-16 Localmed, Inc. Perfusion shunt device and method
US5578009A (en) * 1994-07-20 1996-11-26 Danforth Biomedical Incorporated Catheter system with push rod for advancement of balloon along guidewire
US5591194A (en) * 1994-02-18 1997-01-07 C. R. Bard, Inc. Telescoping balloon catheter and method of use

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3769981A (en) * 1972-02-09 1973-11-06 Kendall & Co Urinary catheter
US4085757A (en) * 1976-04-29 1978-04-25 P Pevsner Miniature balloon catheter method and apparatus
DE3442736C2 (en) * 1984-11-23 1987-03-05 Tassilo Dr.Med. 7800 Freiburg De Bonzel
US4820271A (en) * 1986-03-17 1989-04-11 Deutsch Larry Stuart Guiding catheter system
US4748982A (en) * 1987-01-06 1988-06-07 Advanced Cardiovascular Systems, Inc. Reinforced balloon dilatation catheter with slitted exchange sleeve and method
EP0638327B1 (en) * 1989-01-30 2008-08-20 C.R. Bard, Inc. Rapidly exchangeable coronary catheter
US5040548A (en) * 1989-06-01 1991-08-20 Yock Paul G Angioplasty mehtod
US5061273A (en) * 1989-06-01 1991-10-29 Yock Paul G Angioplasty apparatus facilitating rapid exchanges
US5092839A (en) * 1989-09-29 1992-03-03 Kipperman Robert M Coronary thrombectomy
US5087247A (en) * 1990-08-28 1992-02-11 Cardiovascular Designs, Inc. Balloon perfusion catheter
CA2116724A1 (en) * 1993-03-12 1994-09-13 Richard A. Gambale Windowed catheter and method of use

Patent Citations (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4545367A (en) * 1982-07-16 1985-10-08 Cordis Corporation Detachable balloon catheter and method of use
US4517979A (en) * 1983-07-14 1985-05-21 Cordis Corporation Detachable balloon catheter
US5002556A (en) * 1986-11-29 1991-03-26 Terumo Kabushiki Kaisha Balloon catheter assembly
US4771777A (en) * 1987-01-06 1988-09-20 Advanced Cardiovascular Systems, Inc. Perfusion type balloon dilatation catheter, apparatus and method
US4988356A (en) * 1987-02-27 1991-01-29 C. R. Bard, Inc. Catheter and guidewire exchange system
US5171222A (en) * 1988-03-10 1992-12-15 Scimed Life Systems, Inc. Interlocking peel-away dilation catheter
US5024658A (en) * 1988-06-13 1991-06-18 Kozlov Vladimir S Method and device for the diagnosis and treatment of nasal diseases
US5181921A (en) * 1990-05-25 1993-01-26 Kaken Co., Ltd. Detachable balloon with two self-sealing valves
US5205822A (en) * 1991-06-10 1993-04-27 Cordis Corporation Replaceable dilatation catheter
US5222970A (en) * 1991-09-06 1993-06-29 William A. Cook Australia Pty. Ltd. Method of and system for mounting a vascular occlusion balloon on a delivery catheter
US5267958A (en) * 1992-03-30 1993-12-07 Medtronic, Inc. Exchange catheter having exterior guide wire loops
US5439445A (en) * 1992-08-07 1995-08-08 Boston Scientific Corporation Support catheter assembly
US5591194A (en) * 1994-02-18 1997-01-07 C. R. Bard, Inc. Telescoping balloon catheter and method of use
US5425714A (en) * 1994-03-15 1995-06-20 Cordis Corporation Perfusion catheter with moving body
US5536250A (en) * 1994-04-01 1996-07-16 Localmed, Inc. Perfusion shunt device and method
US5578009A (en) * 1994-07-20 1996-11-26 Danforth Biomedical Incorporated Catheter system with push rod for advancement of balloon along guidewire

Cited By (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040106852A1 (en) * 1996-09-13 2004-06-03 Boston Scientific Corporation Guidewire and catheter locking device and method
US20050177043A1 (en) * 1996-09-13 2005-08-11 Scimed Life Systems, Inc. Guide wire insertion and re-insertion tools and methods of use
US6997908B2 (en) 1996-09-13 2006-02-14 Scimed Life Systems, Inc. Rapid exchange catheter with detachable hood
US20040193142A1 (en) * 1996-09-13 2004-09-30 Boston Scientific Corporation Single operator exchange biliary catheter
US8343105B2 (en) 1996-09-13 2013-01-01 Boston Scientific Scimed, Inc. Multi-size convertible catheter
US20070149948A1 (en) * 1996-09-13 2007-06-28 Boston Scientific Corporation Single operator exchange biliary catheter
US6520951B1 (en) 1996-09-13 2003-02-18 Scimed Life Systems, Inc. Rapid exchange catheter with detachable hood
US20030088153A1 (en) * 1996-09-13 2003-05-08 Scimed Life Systems, Inc. Rapid exchange catheter with detachable hood
US8206283B2 (en) 1996-09-13 2012-06-26 Boston Scientific Corporation Guidewire and catheter locking device and method
US8043208B2 (en) 1996-09-13 2011-10-25 Boston Scientific Scimed, Inc. Guide wire insertion and re-insertion tools and methods of use
US20030199826A1 (en) * 1996-09-13 2003-10-23 Scimed Life Systems, Inc. Multi-size convertible catheter
US6746442B2 (en) 1996-09-13 2004-06-08 Boston Scientific Corporation Single operator exchange biliary catheter
US20030233043A1 (en) * 1996-09-13 2003-12-18 Scimed Life Systems, Inc. Guide wire insertion and re-insertion tools and methods of use
US7846133B2 (en) 1996-09-13 2010-12-07 Boston Scientific Scimed, Inc. Multi-size convertible catheter
US7909811B2 (en) 1996-09-13 2011-03-22 Boston Scientific Corporation Single operator exchange biliary catheter
US7706861B2 (en) 1996-09-13 2010-04-27 Boston Scientific Scimed, Inc. Guide wire insertion and re-insertion tools and methods of use
US7670316B2 (en) 1996-09-13 2010-03-02 Boston Scientific Corporation Guidewire and catheter locking device and method
US8579881B2 (en) 1996-09-13 2013-11-12 Boston Scientific Corporation Single operator exchange biliary catheter
US20050148950A1 (en) * 1996-09-13 2005-07-07 Scimed Life Systems, Inc. Multi-size convertible catheter
US5916195A (en) * 1998-02-04 1999-06-29 Argomed Ltd. Internal catheter
US6740104B1 (en) 1998-05-15 2004-05-25 Advanced Cardiovascular Systems, Inc. Enhanced catheter with alignment means
US20030195546A1 (en) * 1998-05-15 2003-10-16 Solar Ronald J. Enhanced catheter with alignment means
US6780199B2 (en) 1998-05-15 2004-08-24 Advanced Cardiovascular Systems, Inc. Enhanced stent delivery system
US6394995B1 (en) 1998-05-15 2002-05-28 X Technologies Inc. Enhanced balloon dilatation system
US6447501B1 (en) 1998-05-15 2002-09-10 X Technologies Inc. Enhanced stent delivery system
WO2000004942A1 (en) * 1998-07-21 2000-02-03 Heartport, Inc. Multi-lumen catheters and methods of use and manufacture
US7892201B1 (en) * 1999-08-27 2011-02-22 Gore Enterprise Holdings, Inc. Balloon catheter and method of mounting same
US6299595B1 (en) 1999-12-17 2001-10-09 Advanced Cardiovascular Systems, Inc. Catheters having rapid-exchange and over-the-wire operating modes
WO2001066178A1 (en) * 2000-03-06 2001-09-13 Boston Scientific Limited Rapid exchange catheter with detachable hood
US6652485B1 (en) * 2000-05-31 2003-11-25 Advanced Cardiovascular Systems, Inc. Balloon shoulder designs
US6716252B2 (en) 2000-06-30 2004-04-06 Wit Ip Corporation Prostatic stent with localized tissue engaging anchoring means and methods for inhibiting obstruction of the prostatic urethra
US20030125761A1 (en) * 2001-05-08 2003-07-03 Meens Hendrik Jozef Maria Balloon catheter
US6800065B2 (en) 2002-04-04 2004-10-05 Medtronic Ave, Inc. Catheter and guide wire exchange system
US8298134B2 (en) 2002-04-11 2012-10-30 University Of South Florida Eccentric dilation balloons for use with endoscopes
US20050288552A1 (en) * 2002-04-11 2005-12-29 Barthel James S Eccentric dilation balloons for use with endoscopes
US6953431B2 (en) 2002-04-11 2005-10-11 University Of South Florida Eccentric dilation balloons for use with endoscopes
US20070049899A1 (en) * 2002-07-22 2007-03-01 Chambers Technology, Llc Catheter with flexible tip and shape retention
US9168353B2 (en) * 2002-07-22 2015-10-27 Jeffrey W. Chambers Catheter with flexible tip and shape retention
US7867219B2 (en) * 2002-07-22 2011-01-11 Chambers Technologies, Llc Catheter with flexible tip and shape retention
US20120016341A1 (en) * 2002-07-22 2012-01-19 Chambers Jeffrey W Catheter with flexible tip and shape retention
US6966890B2 (en) 2002-08-23 2005-11-22 Medtronic Vascular, Inc. Convertible balloon catheter and manufacture thereof
US20040039409A1 (en) * 2002-08-23 2004-02-26 Noel Coyle Convertible balloon catheter and manufacture thereof
US20040059291A1 (en) * 2002-09-20 2004-03-25 Mcdonnell Paula Catheter with improved transition section
US6893417B2 (en) 2002-09-20 2005-05-17 Medtronic Vascular, Inc. Catheter and guide wire exchange system with improved proximal shaft and transition section
US20040059369A1 (en) * 2002-09-20 2004-03-25 Niall Duffy Catheter and guide wire exchange system
US20040122363A1 (en) * 2002-09-20 2004-06-24 Richard Gribbons Catheter and guide wire exchange system with improved proximal shaft and transition section
US6905477B2 (en) 2002-09-20 2005-06-14 Medtronic Vascular, Inc. Catheter with improved transition section
WO2004026384A3 (en) * 2002-09-20 2004-07-22 Medtronic Ave Inc Catheter with improved transition section
US20090198219A1 (en) * 2003-01-17 2009-08-06 Campbell Carey V Catheter Assembly
US20050021004A1 (en) * 2003-01-17 2005-01-27 Cully Edward H. Puncturing tool for puncturing catheter shafts
US8016752B2 (en) 2003-01-17 2011-09-13 Gore Enterprise Holdings, Inc. Puncturable catheter
US9433745B2 (en) 2003-01-17 2016-09-06 W.L. Gore & Associates, Inc. Puncturing tool for puncturing catheter shafts
US9884170B2 (en) 2003-01-17 2018-02-06 W. L. Gore & Associates, Inc. Catheter assembly
US20040193139A1 (en) * 2003-01-17 2004-09-30 Armstrong Joseph R. Puncturable catheter
US9119937B2 (en) 2003-01-17 2015-09-01 W. L. Gore & Associates, Inc. Puncturable catheter
US20050148820A1 (en) * 2003-02-19 2005-07-07 Boston Scientific Scimed, Inc. Guidewire locking device and method
US7803107B2 (en) 2003-02-19 2010-09-28 Boston Scientific Scimed, Inc. Guidewire locking device and method
US8647256B2 (en) 2003-02-19 2014-02-11 Boston Scientific Scimed, Inc. Guidewire locking device and method
US20040176790A1 (en) * 2003-03-03 2004-09-09 Medtronic Ave, Inc. Single lumen catheter shaft for a balloon catheter
US7273486B2 (en) 2003-04-11 2007-09-25 Medtronic Vascular, Inc. Catheter with a convertible proximal catheter shaft
US20040204736A1 (en) * 2003-04-11 2004-10-14 Medtronic Ave, Inc. Catheter with a convertible proximal catheter shaft
US7208001B2 (en) 2003-04-24 2007-04-24 Medtronic Vascular, Inc. Catheter with detached proximal inflation and guidewire shafts
EP1470834A1 (en) * 2003-04-24 2004-10-27 Medtronic Vascular, Inc. Catheter with detached proximal inflation and guidewire shafts
US20040215165A1 (en) * 2003-04-24 2004-10-28 Medtronic Ave, Inc. Catheter wih detached proximal inflation and guidewire shafts
US20040260329A1 (en) * 2003-06-19 2004-12-23 Richard Gribbons Catheter and guide wire exchange system with decoupled guide member
WO2004112875A1 (en) * 2003-06-19 2004-12-29 Medtronic Vascular Inc. Catheter and guide wire exchange system with decoupled guide member
US20050240193A1 (en) * 2003-09-03 2005-10-27 Kyphon Inc. Devices for creating voids in interior body regions and related methods
US20050070879A1 (en) * 2003-09-26 2005-03-31 Medtronic Vascular, Inc Transition section for a catheter
US20050070881A1 (en) * 2003-09-26 2005-03-31 Richard Gribbons Transition section for a catheter
US20050070880A1 (en) * 2003-09-26 2005-03-31 Medtronic Vascular, Inc. Transition section for a catheter
US20050107819A1 (en) * 2003-11-14 2005-05-19 Medtronic Vascular, Inc. Catheter with a sectional guidewire shaft
US7276045B2 (en) 2003-11-24 2007-10-02 Medtronic Vascular, Inc. Apparatus and method for wire exchange
US20050113803A1 (en) * 2003-11-24 2005-05-26 Medtronic Vascular, Inc. Apparatus and method for wire exchange
US20050137526A1 (en) * 2003-12-17 2005-06-23 Fidelis Machado Balloon catheter with positioning pocket
JP2005177492A (en) * 2003-12-17 2005-07-07 Bristol Myers Squibb Co Balloon catheter with positioning pocket
EP1547639A3 (en) * 2003-12-17 2005-11-23 Bristol-Myers Squibb Company Balloon catheter with positioning pocket
US7727188B2 (en) * 2003-12-17 2010-06-01 Convatec Technologies Inc. Balloon catheter with positioning pocket
US20050212899A1 (en) * 2004-03-24 2005-09-29 Clarke Cyrus B Algorithms and methods for determining laser beam process direction position errors from data stored on a printhead
WO2005094932A1 (en) * 2004-03-24 2005-10-13 Medtronic Vascular Inc. Transition section for a catheter
US8414527B2 (en) 2004-09-21 2013-04-09 Boston Scientific Scimed, Inc. Rapid exchange catheters having a sealed guidewire lumen and methods of making the same
US20060064074A1 (en) * 2004-09-21 2006-03-23 Scimed Life Systems, Inc. Rapid exchange catheters having a sealed guidewire lumen and methods of making the same
US9174025B2 (en) 2004-09-21 2015-11-03 Boston Scientific Scimed, Inc. Rapid exchange catheters having a sealed guidewire lumen and methods of making the same
US8480629B2 (en) 2005-01-28 2013-07-09 Boston Scientific Scimed, Inc. Universal utility board for use with medical devices and methods of use
US20060173438A1 (en) * 2005-01-28 2006-08-03 Boston Scientific Scimed, Inc. Universal utility board for use with medical devices and methods of use
US20080058839A1 (en) * 2006-02-07 2008-03-06 Nobles Anthony A Reverse tapered guidewire and method of use
US8888681B2 (en) 2007-01-03 2014-11-18 Boston Scientific Scimed, Inc. Method and apparatus for biliary access and stone retrieval
US8372000B2 (en) 2007-01-03 2013-02-12 Boston Scientific Scimed, Inc. Method and apparatus for biliary access and stone retrieval
US8480570B2 (en) 2007-02-12 2013-07-09 Boston Scientific Scimed, Inc. Endoscope cap
US20090062769A1 (en) * 2007-04-13 2009-03-05 Boston Scientific Scimed, Inc. Rapid exchange catheter converter
US9131831B2 (en) 2008-02-11 2015-09-15 Boston Scientific Scimed, Inc. Integrated locking device with passive sealing
US20100081878A1 (en) * 2008-05-19 2010-04-01 Boston Scientific Scimed, Inc. Integrated Locking Device With Active Sealing
US8388521B2 (en) 2008-05-19 2013-03-05 Boston Scientific Scimed, Inc. Integrated locking device with active sealing
US8343041B2 (en) 2008-05-19 2013-01-01 Boston Scientific Scimed, Inc. Integrated locking device with passive sealing
US10149601B2 (en) 2009-12-15 2018-12-11 Lumendi Ltd. Method and apparatus for manipulating the side wall of a body lumen or body cavity so as to provide increased visualization of the same and/or increased access to the same, and/or for stabilizing instruments relative to the same
US8979884B2 (en) 2009-12-15 2015-03-17 Cornell University Method and apparatus for stabilizing, straightening, expanding and/or flattening the side wall of a body lumen and/or body cavity so as to provide increased visualization of the same and/or increased access to the same, and/or for stabilizing instruments relative to the same
US9924853B2 (en) * 2009-12-15 2018-03-27 Cornell University Method and apparatus for stabilizing, straightening, expanding and/or flattening the side wall of a body lumen and/or body cavity so as to provide increased visualization of the same and/or increased access to the same, and/or for stabilizing instruments relative to the same
US9986893B2 (en) 2009-12-15 2018-06-05 Cornell University Method and apparatus for manipulating the side wall of a body lumen or body cavity so as to provide increased visualization of the same and/or increased access to the same, and/or for stabilizing instruments relative to the same
US20150133774A1 (en) * 2009-12-15 2015-05-14 Cornell University Method and apparatus for stabilizing, straightening, expanding and/or flattening the side wall of a body lumen and/or body cavity so as to provide increased visualization of the same and/or increased access to the same, and/or for stabilizing instruments relative to the same
WO2016106224A1 (en) * 2014-12-22 2016-06-30 Heuser Richard R Device for treating vascular occlusion

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US5578009A (en) 1996-11-26

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