US5693318A - Stable salicylic acid and peroxide containing skin and hair cleanser composition - Google Patents
Stable salicylic acid and peroxide containing skin and hair cleanser composition Download PDFInfo
- Publication number
- US5693318A US5693318A US08/680,085 US68008596A US5693318A US 5693318 A US5693318 A US 5693318A US 68008596 A US68008596 A US 68008596A US 5693318 A US5693318 A US 5693318A
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- alkali metal
- propylene
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/22—Peroxides; Oxygen; Ozone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/38—Percompounds, e.g. peracids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/02—Anionic compounds
- C11D1/34—Derivatives of acids of phosphorus
- C11D1/345—Phosphates or phosphites
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/2075—Carboxylic acids-salts thereof
- C11D3/2086—Hydroxy carboxylic acids-salts thereof
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/39—Organic or inorganic per-compounds
- C11D3/3902—Organic or inorganic per-compounds combined with specific additives
- C11D3/3937—Stabilising agents
- C11D3/394—Organic compounds
Definitions
- the present invention relates to an aqueous skin and hair cleanser composition comprising peroxides, salicylic acid, and phosphate esters.
- the aqueous skin cleanser composition is unique in that it allows the incorporation of salicylic acid and also provides a stable environment for the peroxides.
- peroxides for example, hydrogen peroxide and salicylic acid for their benefits to human health is a familiar concept to those concerned with human hygiene and to consumers alike.
- the Merck Index Eleventh Edition, 1989 lists the therapeutic uses of hydrogen peroxide as an antiinfective/topical antiseptic.
- Salicylic acid is described as a keratolytic.
- Recent oral care compositions containing hydrogen peroxide have been developed for general consumer use.
- salicylic acid based skin creams are available for general consumer use.
- aqueous based skin and hair care compositions containing both peroxide compounds and salicylic acid are not available. Such a skin and hair care composition would be welcomed by the consumer because it would combine the utility of an antiseptic and a keratolytic agent, leaving the skin and hair both disinfected and refreshed.
- peroxides are such strong oxidizers that they can be used topically only after dilution.
- dilution with water will accelerate their decomposition, especially if the water contains even the smallest concentration of impurities such as metals, metal ions, and metal salts. Peroxides are therefore difficult to process without compromising their activity.
- phosphate esters might be useful in stabilizing peroxides and salicylic acid containing compositions.
- Phosphate esters are known to those skilled in the art as being useful in skin and hair cleansing compositions.
- U.S. Pat. No. 5,124,077, U.S. Pat. No. 4,623,743, and U.S. Pat. No. 4,904,405 disclose the use of phosphate ester surfactants to impart mildness and to cleanse the skin and hair.
- JP Japanese Abstracts, 05009497A (JP), 05001081A (JP), 04108724A (JP), 05009495A (JP), 04249596A (JP), 2242686A (JP) also disclose the use of specific phosphate ester surfactants to impart mildness and cleansing of skin and hair. The focus of these disclosures is also on good foaming of the finished formulation. Some of these disclosures center around the synthesis of glucose or other sugar-based phosphate esters to take maximum advantage of skin mildness. Others show the advantage of the synthesis of trialkylammonium phosphate esters for skin and hair conditioning. However, none of these references describe the use of phosphate esters for improving the solubility and stability of peroxide compounds/salicylic acid containing skin care compositions.
- DE 3583936 (EP 0191214B1) discloses a blemish treatment composition comprising: 0.1-6.10 g boric acid, 0.01-1.6 ml ammonium hydroxide, 0.02-1.2 g camphora, and 0.07-1.1 ml hydrogen peroxide.
- compositions of the present invention be prepared in unpassivated equipment and with standard deionized water which reduces the production costs as compared to preparation in passivated equipment and ultra pure water.
- the skin care composition of the present invention is aesthetically pleasing to the user and is easily dispensed from a mechanical pump, aerosol or a tube.
- An aqueous skin care composition comprising:
- adjunct surfactant c. 0.1 to 50% adjunct surfactant
- phosphate ester selected from one of the following 4 structures or mixtures thereof:
- Each phosphate ester is a mixture of mono-, di- and tri-esters. The mixture is predominately mono-ester.
- An aqueous skin care composition comprising:
- adjunct surfactant c. 0.1 to 50% adjunct surfactant
- phosphate ester selected from one of the following 4 structures or mixtures thereof:
- Each phosphate ester is a mixture of mono-, di- and tri- esters. The mixture is predominately mono-ester.
- the present invention relates to a method for enhancing the water solubility and stability of a salicylic acid and peroxide compound based aqueous skin cleanser comprising adding to said cleanser an effective amount of a phosphate ester, wherein said phosphate ester has one of the following structures:
- Each phosphate ester is a mixture of mono-, di- and tri- esters. The mixture is predominately mono-ester.
- aqueous skin care compositions of the present invention are prepared according to methods known to those skilled in the art by blending peroxide compounds, salicylic acid, adjunct surfactants and phosphate esters in water.
- Peroxides useful in the practice of the present invention include, but are not limited to, hydrogen peroxide, benzoyl peroxide, urea (carbamide) peroxide, zinc peroxide, sodium peroxide and any peroxide formed from organic peracids. These are obtainable from many sources.
- the preferred peroxides, useful for the present invention include hydrogen peroxide, benzoyl peroxide and carbamide peroxide. Particularly preferred peroxides are hydrogen peroxide and benzoyl peroxide.
- Hydrogen Peroxide and benzoyl peroxide are obtainable from a variety of sources at varying concentrations. Hydrogen peroxide is typically available at a concentration of 30%.
- the peroxides are used at a preferred level of 0.5 to 5% by weight, a more preferred level of 0.5 to 3% by weight and a most preferred level of 1 to 2% by weight. Finally, blends of peroxides may be used in the compositions of the present invention.
- Salicylic acid is obtainable from a variety of sources. It is used at a preferred level of 0.5 to 5% by weight, a more preferred level of 0.5 to 3% by weight and a most preferred level of 1 to 2% by weight.
- Adjunct surfactants suitable for use in the skin care composition of the present invention include, nonionic, anionic, and amphoteric.
- nonionic surfactants include:
- polyoxyalkylene polyoxyethylene or polyoxypropylene condensates of aliphatic carboxylic acids, whether linear or branched-chain and unsaturated or saturated, containing from about 8 to about 18 carbon atoms in the aliphatic chain and incorporating from 5 to about 50 ethylene oxide or propylene oxide units.
- Suitable carboxylic acids include "coconut” fatty acids (derived from coconut oil) which contain an average of about 12 carbon atoms, palmitic acid, myristic acid, stearic acid and lauric acid.
- polyoxyalkylene polyoxyethylene or polyoxypropylene condensates of aliphatic alcohols, whether linear- or branched- chain and unsaturated or saturated, containing from about 8 to about 24 carbon atoms and incorporating from about 3 to about 60 ethylene oxide or propylene oxide units.
- PLURAFAC® D 25 and A 39 surfactants are preferred polyoxyalkylene condensates of an aliphatic alcohol type surfactant which is available from BASF Corporation, Mt. Olive, N.J.
- polyoxyalkylene polyoxyethylene or polyoxypropylene condensates of alkyl phenols, whether linear- or branched- chain and unsaturated or saturated, containing from about 6 to about 12 carbon atoms and incorporating from about 5 to about 25 moles of ethylene oxide or propylene oxide.
- Particularly preferred nonionic surfactants are selected polyalkylene oxide block copolymers.
- This class can include polyethoxylated-polypropoxylated propylene glycol sold under the tradename "PLURONIC®” made by the BASF Corporation or polypropoxylated-polyethoxylated ethylene glycol sold under the tradename "PLURONIC-R®” made by the BASF Corporation, Mt. Olive, N.J.
- the first group of compounds are formed by condensing ethylene oxide with a hydrophobic base formed by the condensation of propylene oxide with propylene glycol (see U.S. Pat. No. 2,674,619).
- the hydrophobic portion of the molecule which, of course, exhibits water insolubility, has a molecular weight up to 3600.
- a preferred surfactant of the PLURONIC series is PLURONIC F 127.
- PLURONIC-R® The latter series of compounds called “PLURONIC-R®” are formed by condensing propylene oxide with the polyethoxylated ethylene glycol condensate. This series of compounds is characterized by having an average molecular weight of about between 2000 and 9000 consisting of, by weight, from about 10 to 80 percent polyoxyethylene, and a polyoxypropylene portion having a molecular weight between about 1000 and 3100.
- sucrose and glucose ester non-ionic surfactants sucrose and glucose amide non-ionic surfactants are also useful in the practice of the present invention for their pondered mildness to skin and hair.
- Useful anionic surfactants include the water-soluble salts, preferably the alkali metal, ammonium and substituted ammonium salts, of organic sulfuric acid reaction products having in their molecular structure of alkyl group containing from about 10 to about 20 carbon atoms and a sulfonic acid or sulfuric acid ester group.
- alkyl is the alkyl portion of acyl groups.
- this group of synthetic surfactants are the sodium and potassium alkyl sulfates, especially those obtained by sulfating the higher alcohols (C 8 -C 18 carbon atoms) such as those produced by reducing the glycerides of tallow or coconut oil; and the sodium and potassium alkylbenzenesulfonates in which the alkyl group contains from about 9 to about 15 carbon atoms in straight chain or branched chain configuration, e.g., those of the type described in U.S. Pat. Nos. 2,220,099 and 2,477,383 both of which are incorporated herein by reference.
- Especially valuable are linear straight chain alkylbenzene sulfonates in which the average number of carbon atoms in the alkyl group is from 11 to 13, abbreviated as C 11-13 LAS.
- anionic surfactants suitable for use herein are the sodium alkyl glyceryl ether sulfonates, especially those ethers of higher alcohols derived from tallow and coconut oil; sodium coconut oil fatty acid monoglyceride sulfonates and sulfates; sodium or potassium salts of alkyl phenol ethylene oxide ether sulfates containing from about 1 to about 10 units of ethylene oxide per molecule and from about 8 to about 12 carbon atoms in the alkyl group; and sodium or potassium salts of alkyl ethylene oxide ether sulfates containing from about 1 to about 25 units of ethylene oxide per molecule and from about 10 to about 20 carbon atoms in the alkyl group.
- Other useful anionic surfactants include the water-soluble salts of esters of alpha-sulfonated fatty acids containing from about 6 to 20 carbon atoms in the fatty acid group and from about 1 to 10 carbon atoms in the ester group; water-soluble salts of 2-acyloxy-alkane-1 -sulfonic acids containing from about 9 to about 23 carbon atoms in the alkyl group and from about 8 to 20 carbon atoms in the moiety.
- Particularly preferred surfactants herein are anionic surfactants selected from the group consisting of the alkali metal salts of C 11-13 alkylbenzene sulfonates, C 12-18 alkyl sulfates, C 12-18 alkyl linear polyethoxy sulfates containing from about 1 to about 10 moles of ethylene oxide, and mixtures thereof and nonionic surfactants that are the condensation products of alcohols having an alkyl group containing from about 9 to about 15 carbon atoms with from about 4 to about 12 moles of ethylene oxide per mole of alcohol.
- Amphoteric surfactants useful in the practice of the present invention, include derivatives of heterocyclic secondary and tertiary amines in which the aliphatic moiety can be straight chain or branched, and wherein one of the aliphatic substituents contains from about 8 to 18 carbon atoms and at least one aliphatic substituent contains an anionic water-solubilizing group.
- adjunct surfactants nonionic, anionic and amphoteric, described hereinabove are used at a preferred level of 0.1 to 50% by weight; at a more preferred level of 5 to 30% by weight and at a most preferred level of 10 to 20% by weight.
- the phosphate esters useful in the skin and hair care compositions of the present invention are represented by Formula I, Formula II and Formula III and IV.
- Said skin and hair care compositions of the present invention may be comprised of Formula I, Formula II, Formula III, or Formula IV or mixtures of all four formulas.
- KLEARFACTM AA270 is available from the BASF Corporation, Mr. Olive, N.J.
- l 3.5 to 5.1
- m 1.0-1.6
- p 0.4-1.0
- KLEARFACTM 870 is available from the BASF Corporation, Mt. Olive, N.J.
- Examples of Formula IV include, ethylene diamine, pentaerythritol, triethylene diamine, erythritol, hexamethylene diamine, phenylene diamine.
- Each phosphate ester is a mixture of mono-, di- and tri- esters. The mixture is predominately mono-ester.
- phosphate esters useful in the practice of the present invention include, but are not limited to, RHODAFACTM PC100, PO3, and RA600 (available from Rhone-Pouloenc), and CRODAFOSTM N-3, N-10, N2A, N3A, N5A, and N10A (available from Croda).
- phosphate esters useful in the practice of the present invention are used at levels of 0.1-5% by weight, preferably 1-3% by weight.
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- Life Sciences & Earth Sciences (AREA)
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Abstract
Description
TABLE 1 ______________________________________ I II III ______________________________________ Deionized water 65% w/w 55% w/w 69% w/w PLURONIC ™ F127 (adjunct 25 25 25 surfactant) KLEARFAC ™ 870 (phos. Ester) 1 1 -- KLEARFAC ™ AA270 (phos. Ester) -- -- 2 Alkyl glucoside (adjunct surfactant) 5 10 -- Salicylic Acid 2 2 2 Hydrogen Peroxide 2 2 2 ______________________________________
Claims (8)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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US08/680,085 US5693318A (en) | 1996-07-15 | 1996-07-15 | Stable salicylic acid and peroxide containing skin and hair cleanser composition |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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US08/680,085 US5693318A (en) | 1996-07-15 | 1996-07-15 | Stable salicylic acid and peroxide containing skin and hair cleanser composition |
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US5693318A true US5693318A (en) | 1997-12-02 |
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US08/680,085 Expired - Lifetime US5693318A (en) | 1996-07-15 | 1996-07-15 | Stable salicylic acid and peroxide containing skin and hair cleanser composition |
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Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6071541A (en) * | 1998-07-31 | 2000-06-06 | Murad; Howard | Pharmaceutical compositions and methods for managing skin conditions |
US20020006892A1 (en) * | 2000-07-14 | 2002-01-17 | Carter Daniel C. | Serum albumin compositions for use in cleansing or dermatological products for skin or hair |
US20020031556A1 (en) * | 2000-07-21 | 2002-03-14 | Lindahl Ake R. | Stabilized hydrogen peroxide composition and method of making a stabilized hydrogen peroxide composition |
US6582961B1 (en) * | 1998-12-03 | 2003-06-24 | Redox Chemicals, Inc. | Methods of protecting plants from pathogens |
EP1373447A1 (en) * | 2001-02-27 | 2004-01-02 | P & G-Clairol, Inc. | A method for removing polymer films in the manufacture of aqueous compositions containing acrylates copolymer |
US6673374B2 (en) | 1998-07-31 | 2004-01-06 | Howard Murad | Pharmaceutical compositions and methods for managing skin conditions |
WO2005025486A2 (en) * | 2003-09-13 | 2005-03-24 | Boots Healthcare International Limited | Skincare compositions comprising salicyclic acid |
US6929800B2 (en) | 2001-08-06 | 2005-08-16 | Abdul Rasoul Salman | Nasal passage cleaning composition |
WO2005079745A1 (en) * | 2004-02-19 | 2005-09-01 | Reckitt & Colman (Overseas) Limited | Skincare compositions comprising salicylic acid |
WO2005079746A1 (en) * | 2004-02-19 | 2005-09-01 | Reckitt & Colman (Overseas) Limited | Skincare compositions |
US20100261632A1 (en) * | 2007-08-02 | 2010-10-14 | Advanced Technology Materials, Inc. | Non-fluoride containing composition for the removal of residue from a microelectronic device |
US20110056287A1 (en) * | 2006-12-01 | 2011-03-10 | Gamida For Life B.V. | Fluidic Volume Dispense Verification Tool |
WO2011139794A2 (en) | 2010-04-27 | 2011-11-10 | St. John's Medical Research Institute | A composition for skin sanitization and protection and method of its use |
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EP0191214A2 (en) * | 1984-05-17 | 1986-08-20 | Haviva Rivkin | Purifying liquid cleanser comprising antiseptics |
US4623743A (en) * | 1984-01-03 | 1986-11-18 | Kao Corporation | Phosphoric esters and method for preparing the same |
US4904405A (en) * | 1988-02-29 | 1990-02-27 | Kao Corporation | Aerosol preparations containing mixtures of phosphate esters |
JPH02242686A (en) * | 1989-03-14 | 1990-09-27 | Wako Pure Chem Ind Ltd | Gene of achromobacter protease is and gene product thereof |
JPH04108724A (en) * | 1990-08-30 | 1992-04-09 | Kao Corp | Detergent composition |
US5124077A (en) * | 1989-04-14 | 1992-06-23 | Kao Corporation | Skin detergent composition containing a phosphate ester surfactant and a water soluble chitin derivative |
JPH04249596A (en) * | 1990-12-06 | 1992-09-04 | Kao Corp | Solid detergent composition |
JPH051081A (en) * | 1991-06-19 | 1993-01-08 | Kao Corp | Phosphoric acid ester and/or its salt and production thereof |
JPH059497A (en) * | 1991-07-03 | 1993-01-19 | Kao Corp | Cleaning agent composition |
JPH059495A (en) * | 1991-07-03 | 1993-01-19 | Kao Corp | Cleaning agent composition |
-
1996
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Patent Citations (10)
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US4623743A (en) * | 1984-01-03 | 1986-11-18 | Kao Corporation | Phosphoric esters and method for preparing the same |
EP0191214A2 (en) * | 1984-05-17 | 1986-08-20 | Haviva Rivkin | Purifying liquid cleanser comprising antiseptics |
US4904405A (en) * | 1988-02-29 | 1990-02-27 | Kao Corporation | Aerosol preparations containing mixtures of phosphate esters |
JPH02242686A (en) * | 1989-03-14 | 1990-09-27 | Wako Pure Chem Ind Ltd | Gene of achromobacter protease is and gene product thereof |
US5124077A (en) * | 1989-04-14 | 1992-06-23 | Kao Corporation | Skin detergent composition containing a phosphate ester surfactant and a water soluble chitin derivative |
JPH04108724A (en) * | 1990-08-30 | 1992-04-09 | Kao Corp | Detergent composition |
JPH04249596A (en) * | 1990-12-06 | 1992-09-04 | Kao Corp | Solid detergent composition |
JPH051081A (en) * | 1991-06-19 | 1993-01-08 | Kao Corp | Phosphoric acid ester and/or its salt and production thereof |
JPH059497A (en) * | 1991-07-03 | 1993-01-19 | Kao Corp | Cleaning agent composition |
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Cited By (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6673374B2 (en) | 1998-07-31 | 2004-01-06 | Howard Murad | Pharmaceutical compositions and methods for managing skin conditions |
US6296880B1 (en) | 1998-07-31 | 2001-10-02 | Howard Murad | Pharmaceutical compositions and methods for managing skin conditions |
US7018660B2 (en) | 1998-07-31 | 2006-03-28 | Howard Murad | Pharmaceutical compositions and methods for managing skin conditions |
US20060051429A1 (en) * | 1998-07-31 | 2006-03-09 | Howard Murad | Pharmaceutical compositions and methods for managing skin conditions |
US6383523B1 (en) | 1998-07-31 | 2002-05-07 | Howard Murad | Pharmaceutical compositions and methods for managing skin conditions |
US6071541A (en) * | 1998-07-31 | 2000-06-06 | Murad; Howard | Pharmaceutical compositions and methods for managing skin conditions |
US6582961B1 (en) * | 1998-12-03 | 2003-06-24 | Redox Chemicals, Inc. | Methods of protecting plants from pathogens |
US20060205598A1 (en) * | 1998-12-03 | 2006-09-14 | Redox Chemicals, Inc. | Compositions for protecting plants from pathogens |
US7691630B2 (en) | 1998-12-03 | 2010-04-06 | Redox Chemicals, Inc. | Compositions for protecting plants from pathogens |
US7829072B2 (en) * | 2000-07-14 | 2010-11-09 | Carter Daniel C | Serum albumin compositions for use in cleansing or dermatological products for skin or hair |
US20020006892A1 (en) * | 2000-07-14 | 2002-01-17 | Carter Daniel C. | Serum albumin compositions for use in cleansing or dermatological products for skin or hair |
US20020031556A1 (en) * | 2000-07-21 | 2002-03-14 | Lindahl Ake R. | Stabilized hydrogen peroxide composition and method of making a stabilized hydrogen peroxide composition |
EP1373447A4 (en) * | 2001-02-27 | 2010-02-24 | P & G Clairol Inc | A method for removing polymer films in the manufacture of aqueous compositions containing acrylates copolymer |
EP1373447A1 (en) * | 2001-02-27 | 2004-01-02 | P & G-Clairol, Inc. | A method for removing polymer films in the manufacture of aqueous compositions containing acrylates copolymer |
EP1383859A2 (en) * | 2001-02-27 | 2004-01-28 | P & G-Clairol, Inc. | A method for removing polymer films in the manufacture of aqueous compositions containing anionic amphiphilic polymers |
EP1383859A4 (en) * | 2001-02-27 | 2010-02-24 | P & G Clairol Inc | A method for removing polymer films in the manufacture of aqueous compositions containing anionic amphiphilic polymers |
US6929800B2 (en) | 2001-08-06 | 2005-08-16 | Abdul Rasoul Salman | Nasal passage cleaning composition |
WO2005025486A3 (en) * | 2003-09-13 | 2005-05-06 | Boots Healthcare Int Ltd | Skincare compositions comprising salicyclic acid |
WO2005025486A2 (en) * | 2003-09-13 | 2005-03-24 | Boots Healthcare International Limited | Skincare compositions comprising salicyclic acid |
US20070166337A1 (en) * | 2003-09-13 | 2007-07-19 | Boots Healthcare International Limited | Skincare compositions and methods |
WO2005079745A1 (en) * | 2004-02-19 | 2005-09-01 | Reckitt & Colman (Overseas) Limited | Skincare compositions comprising salicylic acid |
US20080038299A1 (en) * | 2004-02-19 | 2008-02-14 | Reckitt & Colman (Overseas) Limited | Skincare Compositions Comprising Salicylic Acid |
WO2005079746A1 (en) * | 2004-02-19 | 2005-09-01 | Reckitt & Colman (Overseas) Limited | Skincare compositions |
US20110056287A1 (en) * | 2006-12-01 | 2011-03-10 | Gamida For Life B.V. | Fluidic Volume Dispense Verification Tool |
US8549904B2 (en) | 2006-12-01 | 2013-10-08 | Gamida For Life, B.V. | Fluidic volume dispense verification tool |
US20100261632A1 (en) * | 2007-08-02 | 2010-10-14 | Advanced Technology Materials, Inc. | Non-fluoride containing composition for the removal of residue from a microelectronic device |
WO2011139794A2 (en) | 2010-04-27 | 2011-11-10 | St. John's Medical Research Institute | A composition for skin sanitization and protection and method of its use |
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