US4591072A - Repeating dispenser - Google Patents

Repeating dispenser Download PDF

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Publication number
US4591072A
US4591072A US06/716,038 US71603885A US4591072A US 4591072 A US4591072 A US 4591072A US 71603885 A US71603885 A US 71603885A US 4591072 A US4591072 A US 4591072A
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United States
Prior art keywords
dispenser
actuator
upper body
button
cylinder piston
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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US06/716,038
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English (en)
Inventor
Yuji Oshikubo
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Nichiryo Co Ltd
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Nichiryo Co Ltd
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Assigned to NICHIRYO CO., LTD. reassignment NICHIRYO CO., LTD. ASSIGNMENT OF ASSIGNORS INTEREST. Assignors: OSHIKUBO, YUJI
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0234—Repeating pipettes, i.e. for dispensing multiple doses from a single charge

Definitions

  • This invention relates generally to dispensing devices and, particularly to repeating dispensers.
  • Repeating dispensers have been advantageously utilized in chromatographic work, chemical analysis or tests and the like, but it is to be understood that the utility is not confined thereto. Repeating dispensers are utilized to provide, with one filling operation that sucks in a relatively large amount of fluid, repetitive, accurate discharges of exactly the same minute quantities of fluid.
  • U.S. Pat. No. 3,161,323 shows a repeating dispenser of the type aforementioned, and the construction thereof is simple; however, the dispenser has an index rod having rack teeth thereon and which is exposed to the outside, thus, it is difficult to handle the dispenser.
  • German patent disclosure No. P 2736551 discloses a generally tubular repeating dispenser having an actuating button on the top end.
  • the dispenser is very easy to handle; however, there is a shortcoming that the relatively large amount of the liquid sucked and stored in the dispenser can only be dispensed by repeatedly depressing the actuating button, and that it is not easy to disassemble a cylinder and a piston from the dispenser which would be required in changing the liquid being sucked in and dispensed.
  • German patent disclosure No. 2926691 shows another repeating dispenser generally solving the problems aforementioned; however, there are many levers projecting sidewise from a generally tubular main body thus it is objectionable in the handling operation of the piston device.
  • a repeating dispenser comprising a tubular main body, an actuating member slidably disposed in the main body with the upper end thereof projecting out of the upper end of the main body and having a pressure button thereon, a spring for biasing upwards the actuating member, a spring retainer slidably disposed in the main body and normally abutting the lower end of the actuating member to transmit the biasing force of the spring to the actuating member, a stop provided on the inner surface of the main body for abutting engagement by the spring retainer in the non-actuated condition of the dispenser, a pawl pivotally connected to the spring retainer, a pawl spring for biasing the pawl in the radially outward direction, a rack shaft slidably provided on a side surface of the main body and having a plurality of rack teeth thereon for engaging with said pawl, means for preventing the pawl from engaging with the rack shaft when
  • the dispenser operates generally satisfactorily, however, it is required in chemical or pharmaceutical tests or analysis to dispense predetermined same quantities of liquid to a plurality of discrete locations simultaneously so as to perform a multiple member of tests efficiently.
  • a repeating dispenser for repeatedly dispensing uniform quantities of liquid comprises: a tubular body consisting of integrally connected upper and lower body, said upper body having a bottom wall and said lower body having attachment means at its bottom ends for releasably securing a cylinder piston device mounting thereon a plural sets of cylinder and pistons, said lower body having a generally rectangular cross section; radially inwardly projecting means mounted near to the top end of the upper body and defining an upwardly facing abutment and a downwardly facing abutment; an actuating button projecting upwards above the top end of the upper body and having at its bottom a plurality of circumferentially spaced axially stepped surfaces for selectively engaging against said upwardly facing abutment to define one of a plurality of different distances through which said button can be moved downward from its normal position; an actuator non-rotatably and slidably received in the upper body and connected rotatably to said button
  • the rack teeth of the rack shaft do not engage with the pawl in the non-actuated condition, thus it is possible to refill or replenish the dispenser at any desired time and, further, the position of the operating button generally indicates the amount of fluid remaining in the cylinder piston device.
  • FIG. 1 is a longitudinal sectional view taken along line I--I in FIG. 3 of a repeating dispenser according to the invention
  • FIG. 2 is a longitudinal sectional view of the dispenser of FIG. 1, taken along line II--II in FIG. 3;
  • FIG. 3 is a top view of the dispenser of FIG. 1;
  • FIG. 4 is a partial enlarged view of a rack shaft in the dispenser of FIG. 1;
  • FIG. 5 is a sectional view taken along line V--V in FIG. 1;
  • FIG. 6 is a modified form of FIG. 5;
  • FIG. 7 is a perspective view of a cylinder piston device and a lower body of the dispenser of FIG. 1;
  • FIGS. 8-11 are views showing various forms of cylinder and piston in the cylinder piston device according to the invention.
  • the repeating dispenser shown in the drawings comprises a generally tubular main body 10 consisting of a generally tubular upper body 11 and a lower body 12 secured to the upper body and having a generally rectangular cross section.
  • the upper body has a bottom wall 13 having generally rectangular three openings as shown in FIG. 5.
  • the upper body 11 further has on one side of the uppermost portion thereof a sidewise projecting portion 14 for serving as a finger hold, a rough surface portion 15 on the same side for serving as a slip preventing surface, and a vertically extending recess 16 defining a generally planer surface 16a preferably in the side opposite to the finger hold 14 of the upper body 11.
  • the surface 16a is coextensive to radially inner side surface of the opening 13c, as shown in FIG. 5.
  • a generally semicircular guide surface 17 and a flat guide surface 18 as shown in FIG. 5.
  • the guide surface 17 in FIG. 5 is divided into a plurality of guide surface portions 17a, 17b and 17c.
  • An abutment member 19 is secured to the uppermost portion of the upper body 11 and extends downward along one side of the inner surface of the upper body 11 and, an upwardly facing abutment 19a and a downwardly facing abutment 19b is formed on a radially inwardly projecting portion of the abutment member 19.
  • An actuator or actuating member 20 is slidably and non-rotatably provided in the upper body 11, and a spring 21 extends between the actuating member 20 and the bottom wall 13 of the upper body 11 to bias the actuating member 20 against the downwardly facing abutment 19b.
  • An actuating button 22 is rotatably connected to the upper end of the actuating member 20, but the relative axial or vertical displacement therebetween is prevented.
  • two axially spaced ball bearings are provided between the actuating member 20 and the actuating button 22. But the ball bearings may be substituted by any desired publicly known mechanisms.
  • the actuating button 22 has on the lowermost portion a plurality of circumferentially spaced stepped surfaces 22a-22c for cooperating with the upwardly facing abutment 19a of the abutment member 19.
  • the lower end surface of the actuating button is divided into three portions 22a-22c and a clearance s between the abutment 19a and the surface 22a at the condition shown in FIG. 3 and FIG. 1 is the minimum, and when the actuating button 22 is rotated by 120 degrees in the counterclockwise direction, the clearance s increases to a medium and, when the actuating button is further rotated by 120 degrees in the same direction the clearance increases to the maximum.
  • the clearance s between the actuating button 22 and the upwardly facing abutment 19a in the non-actuated condition defines a possible downward stroke of the actuating button 22 or of the actuating member 20.
  • a reference mark 24 and scale or reference numerals 25 as shown in FIG. 3.
  • a ball 26 and a biasing spring 27 in the abutment member 19, and the ball 26 engages with any one of recesses 29 which are provided in the outer circumference of the actuating button 22 for clickingly locating the angular position of the actuating button.
  • the actuating member 20 has integrally a disc-shaped portion 31 on the lower end thereof, and the disc-shaped portion 31 has vertically openings 31a and 31b generally corresponding to and aligning with openings 13a and 13b in the bottom wall 13 respectively.
  • a pawl 32 is pivotally mounted on the disc-shaped portion 31 and extends downward therefrom as shown in FIG. 2.
  • a spring 33 acts on the pawl 32 to bias it in the counterclockwise direction as viewed in FIG. 2.
  • the pawl 32 cooperates with rack teeth 41 on a rack shaft 40 which is connected to a slide 42 and extends vertically upward therefrom.
  • the slide 42 is slidably disposed in the lower body 12.
  • the rack shaft 40 extends through openings 13b and 31b in the bottom wall 13 and the disc-shaped portion 31.
  • one side edge of the opening 13a in the bottom wall 13 engages with an inclined surface portion of the pawl 32 so that a pawl claw of the pawl 32 is spaced from rack teeth 41 of the rack shaft 40.
  • An operating rod 44 is also rigidly secured to the slide 42 and extends vertically upward parallel to and spaced from the rack shaft 40.
  • the rod 44 extends through the opening 13c and along the surface 16a of the vertically extending recess 16 in the upper body 11, and an operating button 45 is connected to the upper end of the rod 44.
  • the lower end portion of the recess 16 is covered by a cover member 34 which is integrally connected to the upper body 11 and cooperates therewith to define the opening 13c at the location of the bottom wall 13.
  • An adjusting screw 35 is mounted on the cover member 34 of the upper body 11 for applying adjustable spring force on the operating rod 44 in the leftward direction as viewed in FIG. 1.
  • the adjusting screw 35 controls the operating speed of the rack shaft 40.
  • a cylinder piston device 50 is detachably mounted on the lower end portion of the lower body 12.
  • the cylinder piston device 50 includes, in the embodiment shown in FIGS. 1, 2 and 7, a mount 51 and four sets of cylinder pistons 53 mounted detachably on the mount 51.
  • Each piston 54 of each cylinder piston has on the upper end a flange 54a which is detachably received in corresponding recess 43 in the slide 42, and each cylinder of the cylinder piston 53 is detachably mounted on the mount 51.
  • the mount 51 has horizontally extending and vertically spaces ridges 52 and 52 which are slidably received in horizontally extending and vertically spaced grooves 12a and 12a formed in the lower body 12 in connecting the cylinder piston device with the lower body 12.
  • Each piston 54 has on its lower end a piston portion 55 for sealingly engaging with cylindrical inner surface of cylinder portion of each cylinder piston 53.
  • a tapered portion is formed in the lower end portion of each cylinder piston 53 so that liquid dispensing operation can be performed easily.
  • the dispenser After sucking a predetermined amount of liquid into the cylinders (usually, the sucking is performed until the operating button 45 takes the uppermost position in the recess 16), the dispenser is displaced onto test tubes or the like and the actuating button 22 is depressed downward.
  • the actuating member 20 moves downward against the biasing force of the spring 21.
  • the pawl 32 supported on the disc-like portion 31 of the actuating member 20 moves downward relative to the bottom wall 13 so that the inclined surface portion of the pawl 32 separates from the edge of the opening 13a and the pawl 32 rotates in the counterclockwise direction as viewed in FIG. 2.
  • the pawl claw of the pawl 32 engages with a rack tooth of the rack shaft 40 and drives downward the rack shaft 40.
  • the downward movement of the actuating member 20 terminates when one of the steps 22a-22c on the lower end of the actuating button 22 engages with the abutment 19a.
  • a predetermined amount of liquid which is determined by the downward stroke of the actuating member 20 is dispensed from each cylinder of the cylinder piston device 50.
  • the non-actuated or released position of the actuating member 20 as shown in FIGS. 1 and 2 is defined by a shoulder of the actuating member 20 engaging with the downwardly facing abutment 19b as shown in FIG. 1.
  • the cylinder piston device 50 can easily be demounted from lower body 12 by displacing it leftward in FIG. 2.
  • Each cylinder piston 53 of the cylinder piston device can easily be demounted from the mount 51 of the cylinder piston device 50 by displacing it rightward in FIG. 2. Therefore, the cylinder pistons 53 may be of a disposable type, and the capacity or the dispensing amount for a given stroke may be changed as desired.
  • the amount of the liquid being dispensed on each actuation is determined by the distance s between the upper surface 19a of the projection 19 and whichever are of the steps 22a-22c is aligned with the projection 19, and the amount can easily be changed by rotating clickingly the actuating button 22.
  • the adjusting screw 35 can effectively control the moving speed of the slide 42, thus, it is possible to prevent the liquid being dispensed from ejecting or spouting from the distal ends of the cylinder piston device 50.
  • FIGS. 8-11 show modified forms of cylinder piston.
  • the cylinder piston 63 comprises a piston 64 which has a flange 64a on the upper end, four angular spaced and vertically extending guide ribs 67 on the upper end portion, an O-ring seal 65 and a tapered portion 66 on the lower end portion.
  • a tip (not shown) may be connected to the lower end of the cylinder piston 63 for sucking liquid therein in upward or sucking stroke of the dispenser.
  • FIG. 9 is generally similar to the embodiment of FIG. 8, but, the O-ring seal 65 in the embodiment of FIG. 8 is substituted by a piston portion 75 slidably engaging with cylinder portion.
  • the embodiment of FIG. 9 also includes cylinder piston 73, piston 74, flange 74a, ribs 77, and tapered portion 76.
  • FIG. 10 shows a further modified form of a cylinder piston.
  • guide ribs 67 in the embodiment of FIG. 8 is modified to extend along substantial length in the cylinder portion of cylinder device 83.
  • An O-ring 85 engages with the cylinder portion of the cylinder piston.
  • the embodiment of FIG. 10 also includes piston 84, flange 84a, ribs 87, and tapered portion 86.
  • FIG. 11 shows another embodiment of the cylinder piston, which is generally similar to the embodiment of FIG. 10 and likewise includes cylinder piston 93, piston 94, flange 94a, piston portion 95, and tapered portion 96.
  • the diameter of cylinder portion of FIGS. 8 and 9 is small as compared with FIGS. 7, 10 and 11, thus, the amount of liquid dispensed from the dispenser in response to a given amount of downward stroke of the guide 42 is small as compared with the latter.
  • the pitch of the rack teeth is 0.9 mm
  • the number of the rack teeth is 51
  • by rotating the actuating button it is possible to control the stroke of the dispenser to correspond to one, two and four pitches of the rack teeth.
  • Two types of cylinder pistons are prepared with each of small diameter cylinder pistons being able to dispense 0.01, 0.02 and 0.04 ml each time, and each large diameter cylinder piston can dispense 0.025, 0.05 and 0.1 ml each time.
  • the actuating button is provided on the top end of the main body, thus, it is easy to depress the actuating button by a finger.
  • the operating button 45 can be operated easily either in sucking the liquid or in discharging the liquid.
  • the cylinder piston device can be exchanged quickly and easily, and the amount of liquid being dispensed can be adjustably varied through a wide range.
  • the adjusting screw can effectively control discharging or dispensing speed which is effective to accurately dispense a predetermined amount of liquid.
  • a plurality of cylinder pistons are exchangeably mounted on the dispenser, thus, it is possible to dispense liquid onto a large number of objects thereby minimizing the labor and time of chemical tests or analysis.

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  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
US06/716,038 1984-03-27 1985-03-26 Repeating dispenser Expired - Lifetime US4591072A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59058891A JPS60202746A (ja) 1984-03-27 1984-03-27 反復分注器
JP59-58891 1984-03-27

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US4591072A true US4591072A (en) 1986-05-27

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US06/716,038 Expired - Lifetime US4591072A (en) 1984-03-27 1985-03-26 Repeating dispenser

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US (1) US4591072A (enrdf_load_stackoverflow)
JP (1) JPS60202746A (enrdf_load_stackoverflow)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4750373A (en) * 1987-01-22 1988-06-14 Shapiro Justin J Adjustable volume, pressure-generating pipette sampler
US4779467A (en) * 1987-01-28 1988-10-25 Rainin Instrument Co., Inc. Liquid-end assembly for multichannel air-displacement pipette
US4967604A (en) * 1985-12-17 1990-11-06 Hamilton Bonaduz Pipette and pipetting apparatus
US5747709A (en) * 1996-03-07 1998-05-05 Nichiryo Co., Ltd. Repetitive pipette
WO2001036100A1 (en) * 1999-10-12 2001-05-25 Glaxo Group Limited Non-contact droplet dispensing system and methods
US20080070187A1 (en) * 2006-09-14 2008-03-20 Bisco, Inc. Dispenser for dental compositions
US20160144356A1 (en) * 2013-06-17 2016-05-26 Waters Technologies Corporation Micropipet for aliquoting small volumes of fluid
EP3260822A1 (de) 2016-06-21 2017-12-27 Eppendorf Ag Mehrkanalspritze für den gebrauch mit einer dosiervorrichtung
US20180318824A1 (en) * 2016-01-07 2018-11-08 A&D Company, Limited Multichannel pipette
WO2025099117A1 (de) * 2023-11-10 2025-05-15 Eppendorf Se Mehrkanal-unterteil für eine fluidübertragungsvorrichtung sowie mehrkanal-fluidübertragungsvorrichtung

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5657861B2 (ja) * 2008-12-30 2015-01-21 光陽化成有限会社 マイクロピペット装置

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3161323A (en) * 1963-05-20 1964-12-15 Hamilton Co Repeating dispenser
US4022207A (en) * 1976-03-25 1977-05-10 Indicon Inc. Actuator for a syringe
US4084730A (en) * 1975-09-18 1978-04-18 Labora Mannheim Gmbh Fur Labortechnik Measuring and pipetting device
US4099548A (en) * 1976-08-25 1978-07-11 Oxford Laboratories Inc. Hand-held pipette for repetitively dispensing precise volumes of liquid
US4316558A (en) * 1980-01-21 1982-02-23 Kubiak Robert J Apparatus for pipetting diluent into a sealed medical container
US4335621A (en) * 1979-08-31 1982-06-22 Kommandiittiyhtio Finnpipette Osmo A. Suovaniemi Pipette
US4406170A (en) * 1979-07-02 1983-09-27 Eppendorf Geratebau Netheler & Hinz Gmbh Repeating pipetting device
US4415101A (en) * 1982-01-22 1983-11-15 Shapiro Justin J Incremental liquid dispensing device
US4467942A (en) * 1982-04-29 1984-08-28 Yuuji Oshikubo Repeating dispenser

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6035458B2 (ja) * 1980-08-02 1985-08-14 アイシン精機株式会社 刺しゆう枠

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3161323A (en) * 1963-05-20 1964-12-15 Hamilton Co Repeating dispenser
US4084730A (en) * 1975-09-18 1978-04-18 Labora Mannheim Gmbh Fur Labortechnik Measuring and pipetting device
US4022207A (en) * 1976-03-25 1977-05-10 Indicon Inc. Actuator for a syringe
US4099548A (en) * 1976-08-25 1978-07-11 Oxford Laboratories Inc. Hand-held pipette for repetitively dispensing precise volumes of liquid
US4406170A (en) * 1979-07-02 1983-09-27 Eppendorf Geratebau Netheler & Hinz Gmbh Repeating pipetting device
US4335621A (en) * 1979-08-31 1982-06-22 Kommandiittiyhtio Finnpipette Osmo A. Suovaniemi Pipette
US4316558A (en) * 1980-01-21 1982-02-23 Kubiak Robert J Apparatus for pipetting diluent into a sealed medical container
US4415101A (en) * 1982-01-22 1983-11-15 Shapiro Justin J Incremental liquid dispensing device
US4467942A (en) * 1982-04-29 1984-08-28 Yuuji Oshikubo Repeating dispenser

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4967604A (en) * 1985-12-17 1990-11-06 Hamilton Bonaduz Pipette and pipetting apparatus
US4750373A (en) * 1987-01-22 1988-06-14 Shapiro Justin J Adjustable volume, pressure-generating pipette sampler
US4779467A (en) * 1987-01-28 1988-10-25 Rainin Instrument Co., Inc. Liquid-end assembly for multichannel air-displacement pipette
US5747709A (en) * 1996-03-07 1998-05-05 Nichiryo Co., Ltd. Repetitive pipette
WO2001036100A1 (en) * 1999-10-12 2001-05-25 Glaxo Group Limited Non-contact droplet dispensing system and methods
US7748980B2 (en) * 2006-09-14 2010-07-06 Bisco, Inc. Dispenser for dental compositions
US20080070187A1 (en) * 2006-09-14 2008-03-20 Bisco, Inc. Dispenser for dental compositions
US20160144356A1 (en) * 2013-06-17 2016-05-26 Waters Technologies Corporation Micropipet for aliquoting small volumes of fluid
US20180318824A1 (en) * 2016-01-07 2018-11-08 A&D Company, Limited Multichannel pipette
US10786810B2 (en) * 2016-01-07 2020-09-29 A&D Company, Limited Multichannel pipette
DE112016006174B4 (de) 2016-01-07 2025-01-30 A & D Company, Limited Mehrkanalpipette
EP3260822A1 (de) 2016-06-21 2017-12-27 Eppendorf Ag Mehrkanalspritze für den gebrauch mit einer dosiervorrichtung
WO2017220673A1 (de) 2016-06-21 2017-12-28 Eppendorf Ag Mehrkanalspritze für den gebrauch mit einer dosiervorrichtung
US11130121B2 (en) 2016-06-21 2021-09-28 Eppendorf Ag Multichannel syringe for use with a metering device
WO2025099117A1 (de) * 2023-11-10 2025-05-15 Eppendorf Se Mehrkanal-unterteil für eine fluidübertragungsvorrichtung sowie mehrkanal-fluidübertragungsvorrichtung

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Publication number Publication date
JPS60202746A (ja) 1985-10-14
JPH054142B2 (enrdf_load_stackoverflow) 1993-01-19

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