US3923836A - Chroman and chromene compounds - Google Patents

Chroman and chromene compounds Download PDF

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Publication number
US3923836A
US3923836A US380446A US38044673A US3923836A US 3923836 A US3923836 A US 3923836A US 380446 A US380446 A US 380446A US 38044673 A US38044673 A US 38044673A US 3923836 A US3923836 A US 3923836A
Authority
US
United States
Prior art keywords
hydroxy
chromene
cyclohexyl
dimethyl
dimethylheptyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US380446A
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English (en)
Inventor
Paul E Bender
Bernard Loev
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Corp filed Critical SmithKline Corp
Priority to US380446A priority Critical patent/US3923836A/en
Priority to BE146419A priority patent/BE817487A/xx
Priority to JP49081653A priority patent/JPS5040572A/ja
Priority to GB3155374A priority patent/GB1419919A/en
Priority to DE2434659A priority patent/DE2434659A1/de
Publication of USB380446I5 publication Critical patent/USB380446I5/en
Application granted granted Critical
Publication of US3923836A publication Critical patent/US3923836A/en
Assigned to SMITHKLINE BECKMAN CORPORATION reassignment SMITHKLINE BECKMAN CORPORATION CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). EFFECTIVE DATE: 03/04/82 Assignors: SMITHKLINE CORPORATION
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/64Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with oxygen atoms directly attached in position 8
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
US380446A 1973-07-18 1973-07-18 Chroman and chromene compounds Expired - Lifetime US3923836A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US380446A US3923836A (en) 1973-07-18 1973-07-18 Chroman and chromene compounds
BE146419A BE817487A (fr) 1973-07-18 1974-07-10 Composes de chromane et de chromene
JP49081653A JPS5040572A (ja) 1973-07-18 1974-07-15
GB3155374A GB1419919A (en) 1973-07-18 1974-07-17 Chroman and chromene compounds
DE2434659A DE2434659A1 (de) 1973-07-18 1974-07-18 Chroman- und chromenverbindungen, ihre salze, verfahren zu ihrer herstellung und arzneimittel

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US380446A US3923836A (en) 1973-07-18 1973-07-18 Chroman and chromene compounds

Publications (2)

Publication Number Publication Date
USB380446I5 USB380446I5 (ja) 1975-01-28
US3923836A true US3923836A (en) 1975-12-02

Family

ID=23501188

Family Applications (1)

Application Number Title Priority Date Filing Date
US380446A Expired - Lifetime US3923836A (en) 1973-07-18 1973-07-18 Chroman and chromene compounds

Country Status (5)

Country Link
US (1) US3923836A (ja)
JP (1) JPS5040572A (ja)
BE (1) BE817487A (ja)
DE (1) DE2434659A1 (ja)
GB (1) GB1419919A (ja)

Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4110347A (en) * 1974-05-31 1978-08-29 Beecham Group Limited Chroman derivatives
US4138401A (en) * 1976-03-29 1979-02-06 The United States Of America As Represented By The Secretary Of The Navy [3,2-g] Pyranoquinoline derivatives
US4296039A (en) * 1977-11-17 1981-10-20 Fidia S.P.A. Selected process for producing monohalogenated derivatives of 7-hydroxy-coumarin
US4788298A (en) * 1985-01-22 1988-11-29 Eastman Kodak Company Process for the preparation of coumarin compounds
US20140288230A1 (en) * 2011-10-19 2014-09-25 Bioformix Inc. Methylene beta-ketoester monomers, methods for making methylene beta-ketoester monomers, polymerizable compositions and products formed therefrom
US9518001B1 (en) 2016-05-13 2016-12-13 Sirrus, Inc. High purity 1,1-dicarbonyl substituted-1-alkenes and methods for their preparation
US9523008B2 (en) 2012-03-30 2016-12-20 Sirrus, Inc. Ink coating formulations and polymerizable systems for producing the same
US9522381B2 (en) 2013-01-11 2016-12-20 Sirrus, Inc. Method to obtain methylene malonate via bis(hydroxymethyl) malonate pathway
US9567475B1 (en) 2016-06-03 2017-02-14 Sirrus, Inc. Coatings containing polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes
US9617354B2 (en) 2015-06-01 2017-04-11 Sirrus, Inc. Electroinitiated polymerization of compositions having a 1,1-disubstituted alkene compound
US9617377B1 (en) 2016-06-03 2017-04-11 Sirrus, Inc. Polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes
US9637564B2 (en) 2014-09-08 2017-05-02 Sirrus, Inc. Emulsion polymers including one or more 1,1-disubstituted alkene compounds, emulsion methods, and polymer compositions
US9676875B2 (en) 2014-09-08 2017-06-13 Sirrus, Inc. Solution polymers including one or more 1,1-disubstituted alkene compounds, solution polymerization methods, and polymer compositions
US9683147B2 (en) 2015-05-29 2017-06-20 Sirrus, Inc. Encapsulated polymerization initiators, polymerization systems and methods using the same
US9752059B2 (en) 2012-11-16 2017-09-05 Sirrus, Inc. Plastics bonding systems and methods
US9790295B2 (en) 2014-09-08 2017-10-17 Sirrus, Inc. Compositions containing 1,1-disubstituted alkene compounds for preparing polymers having enhanced glass transition temperatures
US9828324B2 (en) 2010-10-20 2017-11-28 Sirrus, Inc. Methylene beta-diketone monomers, methods for making methylene beta-diketone monomers, polymerizable compositions and products formed therefrom
US9938223B2 (en) 2015-02-04 2018-04-10 Sirrus, Inc. Catalytic transesterification of ester compounds with groups reactive under transesterification conditions
US10047192B2 (en) 2012-06-01 2018-08-14 Sirrus, Inc. Optical material and articles formed therefrom
US10196481B2 (en) 2016-06-03 2019-02-05 Sirrus, Inc. Polymer and other compounds functionalized with terminal 1,1-disubstituted alkene monomer(s) and methods thereof
US10414839B2 (en) 2010-10-20 2019-09-17 Sirrus, Inc. Polymers including a methylene beta-ketoester and products formed therefrom
US10428177B2 (en) 2016-06-03 2019-10-01 Sirrus, Inc. Water absorbing or water soluble polymers, intermediate compounds, and methods thereof
US10501400B2 (en) 2015-02-04 2019-12-10 Sirrus, Inc. Heterogeneous catalytic transesterification of ester compounds with groups reactive under transesterification conditions
US10607910B2 (en) 2012-11-30 2020-03-31 Sirrus, Inc. Composite compositions for electronics applications
US10913875B2 (en) 2012-03-30 2021-02-09 Sirrus, Inc. Composite and laminate articles and polymerizable systems for producing the same

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636058A (en) * 1966-03-25 1972-01-18 Hoffmann La Roche 7 10 - dihydro - 3 - alkyl - 6h - dibenzo(b d) pyran-6 9(8h)-diones and 5-hydroxy-7-alkyl-4-chromanones

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636058A (en) * 1966-03-25 1972-01-18 Hoffmann La Roche 7 10 - dihydro - 3 - alkyl - 6h - dibenzo(b d) pyran-6 9(8h)-diones and 5-hydroxy-7-alkyl-4-chromanones

Cited By (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4110347A (en) * 1974-05-31 1978-08-29 Beecham Group Limited Chroman derivatives
US4138401A (en) * 1976-03-29 1979-02-06 The United States Of America As Represented By The Secretary Of The Navy [3,2-g] Pyranoquinoline derivatives
US4296039A (en) * 1977-11-17 1981-10-20 Fidia S.P.A. Selected process for producing monohalogenated derivatives of 7-hydroxy-coumarin
US4788298A (en) * 1985-01-22 1988-11-29 Eastman Kodak Company Process for the preparation of coumarin compounds
US10414839B2 (en) 2010-10-20 2019-09-17 Sirrus, Inc. Polymers including a methylene beta-ketoester and products formed therefrom
US9828324B2 (en) 2010-10-20 2017-11-28 Sirrus, Inc. Methylene beta-diketone monomers, methods for making methylene beta-diketone monomers, polymerizable compositions and products formed therefrom
US9969822B2 (en) 2011-10-19 2018-05-15 Sirrus, Inc. Multifunctional monomers, methods for making multifunctional monomers, polymerizable compositions and products formed therefrom
US9512058B2 (en) 2011-10-19 2016-12-06 Sirrus Inc. Multifunctional monomers, methods for making multifunctional monomers, polymerizable compostions and products formed thereform
US9527795B2 (en) * 2011-10-19 2016-12-27 Sirrus, Inc. Methylene beta-ketoester monomers, methods for making methylene beta-ketoester monomers, polymerizable compositions and products formed therefrom
US10604601B2 (en) 2011-10-19 2020-03-31 Sirrus, Inc. Multifunctional monomers, methods for making multifunctional monomers, polymerizable compositions and products formed therefrom
US20140288230A1 (en) * 2011-10-19 2014-09-25 Bioformix Inc. Methylene beta-ketoester monomers, methods for making methylene beta-ketoester monomers, polymerizable compositions and products formed therefrom
US10611861B2 (en) 2011-10-19 2020-04-07 Sirrus, Inc. Multifunctional monomers, methods for making multifunctional monomers, polymerizable compositions and products formed thereform
US10913875B2 (en) 2012-03-30 2021-02-09 Sirrus, Inc. Composite and laminate articles and polymerizable systems for producing the same
US9523008B2 (en) 2012-03-30 2016-12-20 Sirrus, Inc. Ink coating formulations and polymerizable systems for producing the same
US10047192B2 (en) 2012-06-01 2018-08-14 Sirrus, Inc. Optical material and articles formed therefrom
US9752059B2 (en) 2012-11-16 2017-09-05 Sirrus, Inc. Plastics bonding systems and methods
US10607910B2 (en) 2012-11-30 2020-03-31 Sirrus, Inc. Composite compositions for electronics applications
US9522381B2 (en) 2013-01-11 2016-12-20 Sirrus, Inc. Method to obtain methylene malonate via bis(hydroxymethyl) malonate pathway
US10086355B2 (en) 2013-01-11 2018-10-02 Sirrus, Inc. Method to obtain methylene malonate via bis(hydroxymethyl) malonate pathway
US9676875B2 (en) 2014-09-08 2017-06-13 Sirrus, Inc. Solution polymers including one or more 1,1-disubstituted alkene compounds, solution polymerization methods, and polymer compositions
US10081685B2 (en) 2014-09-08 2018-09-25 Sirrus, Inc. Emulson polymers including one or more 1,1-disubstituted alkene compounds, emulson methods, and polymer compositions
US9890227B1 (en) 2014-09-08 2018-02-13 Sirrus, Inc. Compositions containing 1,1-di-substituted alkene compounds for preparing polymers having enhanced glass transition temperatures
US10308802B2 (en) 2014-09-08 2019-06-04 Sirrus, Inc. Polymers including one or more 1,1-disubstituted alkene compounds and polymer compositions thereof
US9969819B2 (en) 2014-09-08 2018-05-15 Sirrus, Inc. Pressure sensitive adhesive including a 1,1-disubstituted alkene compound
US10184073B2 (en) 2014-09-08 2019-01-22 Sirrus, Inc. Emulsion including polymers containing a 1,1-disubstituted alkene compound, adhesives, coatings, and methods thereof
US9637564B2 (en) 2014-09-08 2017-05-02 Sirrus, Inc. Emulsion polymers including one or more 1,1-disubstituted alkene compounds, emulsion methods, and polymer compositions
US9790295B2 (en) 2014-09-08 2017-10-17 Sirrus, Inc. Compositions containing 1,1-disubstituted alkene compounds for preparing polymers having enhanced glass transition temperatures
US10633566B2 (en) 2014-09-08 2020-04-28 Sirrus, Inc. Polymers containing a 1,1-disubstituted alkene compound
US11021617B2 (en) 2014-09-08 2021-06-01 Sirrus, Inc. Polymers including one or more 1,1-disubstituted alkene compounds and polymer compositions thereof
US10167348B2 (en) 2014-09-08 2019-01-01 Sirrus, Inc. Solution polymers formed from methylene malonate monomers, polymerization, and solution polymer products
US10519257B2 (en) 2014-09-08 2019-12-31 Sirrus, Inc. Compositions containing 1,1-di-carbonyl-substituted alkene compounds for preparing polymers having enhanced glass transition temperatures
US10501400B2 (en) 2015-02-04 2019-12-10 Sirrus, Inc. Heterogeneous catalytic transesterification of ester compounds with groups reactive under transesterification conditions
US9938223B2 (en) 2015-02-04 2018-04-10 Sirrus, Inc. Catalytic transesterification of ester compounds with groups reactive under transesterification conditions
US10087272B2 (en) 2015-05-29 2018-10-02 Sirrus, Inc. Encapsulated polymerization initiators, polymerization systems and methods using the same
US9683147B2 (en) 2015-05-29 2017-06-20 Sirrus, Inc. Encapsulated polymerization initiators, polymerization systems and methods using the same
US9617354B2 (en) 2015-06-01 2017-04-11 Sirrus, Inc. Electroinitiated polymerization of compositions having a 1,1-disubstituted alkene compound
US9518001B1 (en) 2016-05-13 2016-12-13 Sirrus, Inc. High purity 1,1-dicarbonyl substituted-1-alkenes and methods for their preparation
US10428177B2 (en) 2016-06-03 2019-10-01 Sirrus, Inc. Water absorbing or water soluble polymers, intermediate compounds, and methods thereof
US10196481B2 (en) 2016-06-03 2019-02-05 Sirrus, Inc. Polymer and other compounds functionalized with terminal 1,1-disubstituted alkene monomer(s) and methods thereof
US10150886B2 (en) 2016-06-03 2018-12-11 Sirrus, Inc. Coatings containing polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes
US10087283B2 (en) 2016-06-03 2018-10-02 Sirrus, Inc. Polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes
US9745413B1 (en) 2016-06-03 2017-08-29 Sirrus, Inc. Polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes
US9718989B1 (en) 2016-06-03 2017-08-01 Sirrus, Inc. Coatings containing polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes
US9617377B1 (en) 2016-06-03 2017-04-11 Sirrus, Inc. Polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes
US9567475B1 (en) 2016-06-03 2017-02-14 Sirrus, Inc. Coatings containing polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes

Also Published As

Publication number Publication date
GB1419919A (en) 1975-12-31
BE817487A (fr) 1975-01-10
USB380446I5 (ja) 1975-01-28
DE2434659A1 (de) 1975-02-06
JPS5040572A (ja) 1975-04-14

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Legal Events

Date Code Title Description
AS Assignment

Owner name: SMITHKLINE BECKMAN CORPORATION

Free format text: CHANGE OF NAME;ASSIGNOR:SMITHKLINE CORPORATION;REEL/FRAME:004080/0769

Effective date: 19820304

Owner name: SMITHKLINE BECKMAN CORPORATION, PENNSYLVANIA

Free format text: CHANGE OF NAME;ASSIGNOR:SMITHKLINE CORPORATION;REEL/FRAME:004080/0769

Effective date: 19820304