US3893767A - Electro-optical system for cancellation of the effects of red blood cells in a sample of biological cells - Google Patents

Electro-optical system for cancellation of the effects of red blood cells in a sample of biological cells Download PDF

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Publication number
US3893767A
US3893767A US408817A US40881773A US3893767A US 3893767 A US3893767 A US 3893767A US 408817 A US408817 A US 408817A US 40881773 A US40881773 A US 40881773A US 3893767 A US3893767 A US 3893767A
Authority
US
United States
Prior art keywords
light
cell
cells
sample
signals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US408817A
Other languages
English (en)
Inventor
Mack J Fulwyler
Garret Francis Ziffer
Gerard Adelard Paquette
Michael Thomas Gilmore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Coulter Electronics Inc
Original Assignee
Coulter Electronics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US408817A priority Critical patent/US3893767A/en
Application filed by Coulter Electronics Inc filed Critical Coulter Electronics Inc
Priority to FR7434788A priority patent/FR2248509B1/fr
Priority to CH1385174A priority patent/CH592877A5/xx
Priority to GB4477374A priority patent/GB1476793A/en
Priority to IT53571/74A priority patent/IT1024317B/it
Priority to JP11830074A priority patent/JPS5433758B2/ja
Priority to SE7413014A priority patent/SE404259B/xx
Priority to NL7413572A priority patent/NL7413572A/xx
Priority to CA211,564A priority patent/CA1018796A/en
Priority to DE2450112A priority patent/DE2450112C3/de
Application granted granted Critical
Publication of US3893767A publication Critical patent/US3893767A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1468—Electro-optical investigation, e.g. flow cytometers with spatial resolution of the texture or inner structure of the particle
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
US408817A 1973-10-23 1973-10-23 Electro-optical system for cancellation of the effects of red blood cells in a sample of biological cells Expired - Lifetime US3893767A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
US408817A US3893767A (en) 1973-10-23 1973-10-23 Electro-optical system for cancellation of the effects of red blood cells in a sample of biological cells
CH1385174A CH592877A5 (ja) 1973-10-23 1974-10-16
GB4477374A GB1476793A (en) 1973-10-23 1974-10-16 Nondestructively analysing biological cells using opto- electrical apparatus
IT53571/74A IT1024317B (it) 1973-10-23 1974-10-16 Sistema elettro ottico la cancellazione degli effetti dei glo buli rossi in un campione di cellu le biologiche
FR7434788A FR2248509B1 (ja) 1973-10-23 1974-10-16
JP11830074A JPS5433758B2 (ja) 1973-10-23 1974-10-16
SE7413014A SE404259B (sv) 1973-10-23 1974-10-16 Sett och apparat for att analysera biologiska celler
NL7413572A NL7413572A (nl) 1973-10-23 1974-10-16 Werkwijze voor het automatisch analyseren van biologische cellen.
CA211,564A CA1018796A (en) 1973-10-23 1974-10-16 Electro-optical system
DE2450112A DE2450112C3 (de) 1973-10-23 1974-10-22 Verfahren und Anordnung zur zerstörungsfreien Analyse biologischer Zeilen einer mindestens zwei unterschiedliche, licht bekannter Wellenlänge unterschiedlich stark absorbierende Zellentypen in zueinander festgelegter Lage enthaltenden Probe

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US408817A US3893767A (en) 1973-10-23 1973-10-23 Electro-optical system for cancellation of the effects of red blood cells in a sample of biological cells

Publications (1)

Publication Number Publication Date
US3893767A true US3893767A (en) 1975-07-08

Family

ID=23617891

Family Applications (1)

Application Number Title Priority Date Filing Date
US408817A Expired - Lifetime US3893767A (en) 1973-10-23 1973-10-23 Electro-optical system for cancellation of the effects of red blood cells in a sample of biological cells

Country Status (10)

Country Link
US (1) US3893767A (ja)
JP (1) JPS5433758B2 (ja)
CA (1) CA1018796A (ja)
CH (1) CH592877A5 (ja)
DE (1) DE2450112C3 (ja)
FR (1) FR2248509B1 (ja)
GB (1) GB1476793A (ja)
IT (1) IT1024317B (ja)
NL (1) NL7413572A (ja)
SE (1) SE404259B (ja)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4030888A (en) * 1975-02-28 1977-06-21 Toa Medical Electronics Co., Ltd. Automatic blood analyzer
US4095898A (en) * 1976-06-10 1978-06-20 Coulter Electronics, Inc. Particle analysis system with photochromic filter
US4097845A (en) * 1976-11-01 1978-06-27 Rush-Presbyterian-St. Luke's Medical Center Method of and an apparatus for automatic classification of red blood cells
US4672038A (en) * 1984-10-19 1987-06-09 Abbott Laboratories Optical readout for blood sample analysis
EP0290272A1 (en) * 1987-05-08 1988-11-09 Hamamatsu Photonics K.K. Examination apparatus for measuring oxygenation
US20100156640A1 (en) * 2008-12-19 2010-06-24 Forster Ian J Optical control of rfid chips
CN107466364A (zh) * 2015-04-02 2017-12-12 奥里巴Abx股份有限公司 对颗粒进行计数的设备

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3014563A1 (de) * 1980-04-16 1981-10-29 Merck Patent Gmbh, 6100 Darmstadt Verfahren zur bestimmung leukaemischer zellen
FR2515352B1 (fr) * 1981-10-22 1987-07-17 Int Remote Imaging Systems Inc Procede d'analyse de particules contenues dans un echantillon d'un fluide dilue
US5310674A (en) * 1982-05-10 1994-05-10 Bar-Ilan University Apertured cell carrier
US5272081A (en) * 1982-05-10 1993-12-21 Bar-Ilan University System and methods for cell selection
GB8604751D0 (en) * 1986-02-26 1986-04-03 Analytical Instr Ltd Colour analyser

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2875666A (en) * 1953-07-13 1959-03-03 Ohio Commw Eng Co Method of simultaneously counting red and white blood cells
US3315229A (en) * 1963-12-31 1967-04-18 Ibm Blood cell recognizer
US3413464A (en) * 1965-04-29 1968-11-26 Ibm Method for measuring the nucleic acid in biological cells after enhancement in an acidic solution
US3503684A (en) * 1966-11-09 1970-03-31 Perkin Elmer Corp Method and apparatus for detecting mitotic blood cells on a blood cell sample slide
US3560754A (en) * 1965-11-17 1971-02-02 Ibm Photoelectric particle separator using time delay

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2875666A (en) * 1953-07-13 1959-03-03 Ohio Commw Eng Co Method of simultaneously counting red and white blood cells
US3315229A (en) * 1963-12-31 1967-04-18 Ibm Blood cell recognizer
US3413464A (en) * 1965-04-29 1968-11-26 Ibm Method for measuring the nucleic acid in biological cells after enhancement in an acidic solution
US3560754A (en) * 1965-11-17 1971-02-02 Ibm Photoelectric particle separator using time delay
US3503684A (en) * 1966-11-09 1970-03-31 Perkin Elmer Corp Method and apparatus for detecting mitotic blood cells on a blood cell sample slide

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4030888A (en) * 1975-02-28 1977-06-21 Toa Medical Electronics Co., Ltd. Automatic blood analyzer
US4095898A (en) * 1976-06-10 1978-06-20 Coulter Electronics, Inc. Particle analysis system with photochromic filter
US4097845A (en) * 1976-11-01 1978-06-27 Rush-Presbyterian-St. Luke's Medical Center Method of and an apparatus for automatic classification of red blood cells
US4672038A (en) * 1984-10-19 1987-06-09 Abbott Laboratories Optical readout for blood sample analysis
EP0290272A1 (en) * 1987-05-08 1988-11-09 Hamamatsu Photonics K.K. Examination apparatus for measuring oxygenation
US4901238A (en) * 1987-05-08 1990-02-13 Hamamatsu Photonics Kabushiki Kaisha Oximeter with monitor for detecting probe dislodgement
US20100156640A1 (en) * 2008-12-19 2010-06-24 Forster Ian J Optical control of rfid chips
US9135547B2 (en) * 2008-12-19 2015-09-15 Avery Dennison Corporation Optical control of RFID chips
CN107466364A (zh) * 2015-04-02 2017-12-12 奥里巴Abx股份有限公司 对颗粒进行计数的设备
US10641697B2 (en) 2015-04-02 2020-05-05 Horiba Abx Sas Device for counting particles

Also Published As

Publication number Publication date
JPS5068588A (ja) 1975-06-07
GB1476793A (en) 1977-06-16
IT1024317B (it) 1978-06-20
DE2450112A1 (de) 1975-05-22
JPS5433758B2 (ja) 1979-10-23
SE404259B (sv) 1978-09-25
DE2450112C3 (de) 1981-01-15
NL7413572A (nl) 1975-04-25
FR2248509A1 (ja) 1975-05-16
SE7413014L (ja) 1975-04-24
DE2450112B2 (de) 1980-04-10
FR2248509B1 (ja) 1980-09-12
CH592877A5 (ja) 1977-11-15
CA1018796A (en) 1977-10-11

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