US3857387A - Ultrasonic cataract removal method and apparatus - Google Patents
Ultrasonic cataract removal method and apparatus Download PDFInfo
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- US3857387A US3857387A US00318429A US31842972A US3857387A US 3857387 A US3857387 A US 3857387A US 00318429 A US00318429 A US 00318429A US 31842972 A US31842972 A US 31842972A US 3857387 A US3857387 A US 3857387A
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- 238000000034 method Methods 0.000 title claims description 81
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00736—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
- A61F9/00745—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments using mechanical vibrations, e.g. ultrasonic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2217/00—General characteristics of surgical instruments
- A61B2217/002—Auxiliary appliance
- A61B2217/007—Auxiliary appliance with irrigation system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M3/00—Medical syringes, e.g. enemata; Irrigators
- A61M3/02—Enemata; Irrigators
- A61M3/0279—Cannula; Nozzles; Tips; their connection means
Definitions
- IZB-Z MA AU 335 EX United States Patent 1191 Shock 1 Dec. 31, 1974- 1541 ULTRASONIC CATARACT REMOVAL 3,736,938 0/1973 Eward m1 128/305 METHOD AND APPARATUS Primary Examiner-Channing L. Pace [75] Inventor. John P. Shock, San Rafael, Cahf. Attorney Agent, or Firm Leonard Surefi- [73] Assignee: Ultrasonic Systems, Inc.,
- A61h 23/00, A6lf 9/00 adapted to have a vibrating tool to reduce the voltttttc [58] Field 01 Search 128/24 A, 305 of the cataract and thereafter, through the Simultaneous introduction of a fluid and creating a flow, the
- the ultrasonic surgical procedure as disclosed in the abovereferenced patent requires a complexity of interacting steps having a balance to each other that must be performed in order to have a successful surgical procedure. Furthermore, due to the complexity of the equipment, the surgeon is therefore dependent upon a skilled technician who must be likewise trained and made available for each operation. This, in addition to other factors, would increase the cost per operation and the availability of the equipment to ophthalmologists who might not have a large cataract practice.
- This combined system is inserted into the anterior chamber of the eye through a small incision and provision is made for hydrodynamic flow both in the area between the two above-indicated tubes and within the interior of the vibrating tube. It is of the greatest importance that a proper balance be established between the two flows referenced to.
- the first flow is a gravity flow of liquid into the interior chamber.
- the second flow is the result of a suction of liquid out of the chamber through the interior of the hollow vibrating tube. It is essential that these two flows be balanced so that there is neither an excessive build-up pressure in the anterior chamber or a reduction in pressure which could cause a collapse of the anterior chamber.
- An object of the present invention is to provide an improved method and apparatus for progressively removing a mass of tissue from a human or other animal.
- Another object of the present invention is to provide an improved method and apparatus for removing cataracts having different grades of hardness.
- Another object of the present invention is to provide a method and apparatus for selectively fracturing and removing layers of living organic tissue from a biological organism.
- Another object of the present invention is to provide a method and apparatus for the removal of living organic tissue from a cataract in a rapid manner and with the exertion of a minimum of physical energy by the surgeon affecting such removal.
- the surgical procedure in accordance with the present invention is essentially as follows:
- the patient is given a local anesthetic which consists of a lid block and a retrobulbar injection.
- This local anesthetic is all that is generally required for conventional cataract removal procedures; but I might point out that, with the prior art ultrasonic cataract removal procedures to data, a general anesthetic has been given in that. due to the greater delicacy of the operating procedure, it has been more important that there be absolutely no movement of the eye during the operating procedure.
- a small limbal or fornix based conjunctiva] flap is performed.
- a 4mm limbal incision is made into the anterior chamber.
- the aqueous is generally removed from the anterior chamber and a small amount of air is inserted.
- a small cystotome is inserted through the incision and the anterior capsule of the lens is removed. If the anterior capsule is not completely withdrawn by the cystotome, then a small pair of capsule forceps can be inserted to complete the removal. If used, the air is removed and normal saline is inserted into the anterior chamber.
- a thin walled approximately 19 gauge metallic needle which can be vibrated with ultrasonic energy is inserted into the anterior chamber through the incision.
- a slow drip of physiological saline is allowed to flow continuously through the needle. This flow of fluid through the needle is accomplished merely by providing a gravity feed flow from an intravenous pole arrangement.
- the tip is ultrasonically energized for a short period of time which fragments the material immediately adjacent to the tip.
- the period during which the tip is energized may vary anywhere from approximately a millisecond to a second, depending upon the speed of foot movement on the foot switch. The surgeon selects the interval of energization to allow complete and perfect control of the operative procedure.
- the mass of material forming the cataract to be removed is initially broken into a plurality of fragmented sub-masses or major sections which are each thereafter removed in its entirety or further fragmented into a plurality of particle size masses such that it may exit from the incision with the irrigation fluids.
- the surgeon initially cross-drills or bores a plurality of apertures into the cataract such as to create a tunneling effect and these cross-bores or apertures are formed by the vibrating ultrasonic member such that a plurality of sub-masses are formed during this aspect of the surgical operation.
- These sub-masses are thereafter individually either reduced in size or are of an initial size to permit their exiting through the incision around the outer surface of the tool member which is extending through the incision.
- the tip or output edge of the needle-like tool member is positioned in engagement with the immediate portion of the cataract to be removed, prior to ultrasonically energizing the tip of the needle tool member.
- a portion of the cataract in surrounding relation thereto is fragmented and the size of the fragmented section is a function of the hardness and nature of the cataract material; for example, the fragments may range from practically invisibility to sections of millimeter dimensions.
- the ultrasonic needle can be re-applied to it and further fragmented. This process of intermittent engagement and energization of the tip is repeated until such time as the entire cataract is fragmented and removed through the incision by the lavage. This ability to handle such fragmented material is typical of the delicate and accurate control of which this novel procedure is capable.
- FIG. 1 is a somewhat schematic view of the ultrasonic system for driving a tool member adapted for the surgical procedure claimed herein;
- FIG. 2 is an enlarged view in cross-section of the tool member in assembled relation to the ultrasonic system for use herein;
- FIG. 3 is a greatly enlarged section of a portion of the human eye illustrating the insertion of the tool member in accordance with the invention
- FIGS. 4-9 are greatly enlarged diagrammatic views to help illustrate the theory of the present invention with respect to the removal of the mass
- FIG. is a diagrammatic view similar to FIG. 3 illustrating the process of removing the respective masses.
- FIGS. 11-15 are greatly enlarged diagrammatic views to illustrate the exiting of each mass or particle from the incision.
- apparatus 10 for ultrasonically removing a mass such as a cataract from an animal may include instrument means 12 for effecting the necessary high frequency vibrations of the tool member or probe 14 having a relatively sharp output edge or tip 15.
- instrument means 12 for effecting the necessary high frequency vibrations of the tool member or probe 14 having a relatively sharp output edge or tip 15.
- Operatively associated with the instrument means 12 is generating means 18 for powering same and fluid supply means 20 for providing a fluid 22 at the operative site.
- the instrument means 12 may be in the form of a handpiece adapted for being hand held and generally comprising a tubular housing 24 with an ultrasonic motor or transducer 25 being contained therein and having an output end or stem 26 of the motor 25 extending axially beyond the front end 28 of the housing 24 and to which the tool member 14 is coupled.
- the ultrasonic motor 25 is energized by the generator 18, contained in a cabinet 30 with a power cable 32 connecting the two together.
- the generator 18 is an oscillator adapted to produce electrical energy having an ultrasonic frequency and contains a shut-off switch 34 and a power control knob 35 with an indicator light 36 on the front panel 38 of the generator 18 to permit the surgeon to properly monitor and adjust the power transmitted to the ultrasonic motor 25.
- a foot switch 40 connected thereto to be used by the surgeon and a plug 42 with a power cable 44 which is plugged into a conventional outlet in order to obtain the necessary electricity for the apparatus 10.
- the ultrasonic motor 25 may be one of a variety of electromechanical types such as piezoelectric or magnetostrictive.
- the ultrasonic motor 25 is designed to operate at a desired frequency generally in the range of 5,000 cycles per second to 500,000 cycles per second, but preferably in the range of l5,000 cycles per second to 100,000 cycles per second and the front output end 26 which is adapted to receive a variety of working tools 15 and wherein each working tool is mechanically coupled to the motor so that it is vibrated at the proper amplitude of vibration.
- the transducer of the ultrasonic motor is longitudinally dimensioned so as to have lengths which are whole multiples of half-wavelengths of the waves generated therein such that the exterior working end of the ultrasonic motor is a longitudinal loop of motion as indicated by double headed arrow 45.
- This longitudinal motion is converted into a lateral motion as indicated by the double headed arrow 46 at the tip 15.
- the amplitude of longitudinal vibration is generally in the range of 0.0001 to 0.010 and the hyper accelerations exceed 1,000g at the tool tip 15.
- the design of the output end of the motor 25 and the tool 15 may be designed to either magnify or reduce the amplitude of the vibrations received from the ultrasonic motor 25 and may be designed so as to obtain either longitudinal, elliptical, orbital, flexural, lateral, etc., vibrational modes at the tip.
- the tool 15 as seen in FIG. 2 may be in the form that is adapted to be removably secured to the shank end 26 of the instrument means'l2 and which is seen to have an angularly disposed base portion 48 with respect to the longitudinally extending shank portion 26 of the ultrasonic motor 25.
- the base portion 48 has a spaced apart front face surface 50 and rear face surface 52 with a threaded portion 54 extending therein.
- the tool 14 may be of a needle-like member having a rear section 56 with a threaded portion 58 adapted to meet with the complimentary threads 54 in the front end 48 and having an axially extending bore 60 extending from its rear end 62 to its front tip 15 to permit a fluid to enter therethrough as hereinafter explained in detail.
- the tool 14 further includes gripping means 65 in the form of a mid-section 66 which may be of a hexognonal shape to permit its being gripped by an instrument such as a pair of pliers or wrench for proper tightening such that the threaded stud 58 screws into the tapped hole 54 for effecting the rigid connection of the tool 14 to stem 50.
- a radial flange 68 is integrally formed with the mid-section 66 and rear section 56 and abuts the front face 50.
- the shaft portion 55 of the tool member 14 is integrally formed with the mid-section 66 and rear section 56 with the bore 60 extending axially there through to provide a fluid passage.
- the operative tip 14 is preferably formed of an extremely hard, sterilizable material, such as titanium, and for most surgical applications is made of extremely small dimension. Since this is the only portion of the instrument that is brought into contact with the tissue to be broken apart and removed, it will be evident that only a very short incision need to be made in the outer surface to permit access of the tip.
- the diameter of the outer surface of the shaft portion 55' may be in the range of 0.0l0 inch to 0.250 inch but is preferably in the range of 0.030 inch to 0.050 inch.
- the inner bore 60 being of a size to permit a continuous flow of fluid therethrough. As seen in FIG. 2 and actue angled taper 72 is provided to leave a relatively sharp, rounded edge 15.
- the shape, length, and dimensions of the tool member may vary depending upon the type of mass or cataract to be removed.
- the fluid supply means may include the container or reservoir 75 of the intravenous type that is being suspended from a handle 76 that is supported by means of a support arm or hook 78 which is coupled to a support surface 80. From the front end 82 of the reservoir 75 extends a tubular member 84 connected by a rear coupling member 85 to a front coupling member 86 which in turn is connected to a tube and fitting such that the fluid 22 may flow therethrough and into the tool member 14 from an exterior source. Mounted on the tubular member 84 is a stop cock or valve 87 having a control knob 89 to control the fluid rate through the tubular member 84. Although not shown, if so desired, the fluid may be supplied directly through the instrument and through the tool.
- the coupling members 85 and 86 are in two sections adapted to be removably coupled to each other and as seen in FIG. 2, the tube 88 at its lower end 92 is in telescopic relationship to the rear end 94 which has a shoulder 95 secured in a fluid tight manner as by soldering or brazing to the rear surface 52 of the shank 48.
- the passageway 96 connects with the bore 60 of the tool member 14 to permit a continuous flow of fluid to the operative site.
- FIGS. 3-15 A portion of a simplified cross section of a human eye 100 is shown to illustrate the manner in which the device is employed.
- the opaque lens or cataract which is to be broken apart and removed to is designated by the numeral 102 and is encased in a membrane having a rear portion 105 known as the posterior capsule.
- the iris is designated by the numeral 106 and the major gel-filled portion of the eye, or vitreous, is shown at 108.
- the cornea, the transparent outer surface of the eye, is shown at 110.
- suitable drugs are administered to dilate the iris to its maximum extent. so that as much as the anterior capsule 102 is exposed as is possible.
- a small incision 112 is then made in the transparent cornea as far as possible from the center of the pupil area. This incision is made initially only about 1 to 3 mm. in length to provide access for a knife to enter the anterior chamber for removal of the anterior capsule. After the capsule is removed, the incision is enlarged to 2-12 mm., usually 4-6 mm., to provide proper access for the operative tip of the vibratory assembly.
- the corneal incision is enlarged, and the operative tip is inserted into the body of the cataract 102, whereby the lens tissue mass is broken apart into minute particles.
- a supply of irrigating fluid is flowing continuously through the operative tip while the transducer is energized periodically for very short intervals of time.
- cataracts which exist in an enclosed area in an animal may be removed with ultrasonic energy when a tool having a relatively sharp output edge is inserted in an incision having a width of approximately 0.040 inch and vibrating the tool ultrasonically such that as one progressively engages the cataract material that there is a reduction in the size thereof until sufficient room or space between the outer surface 70 of the tool member 14 and the width of the incision 112 to permit the reduced mass or portions of the cataract to flow outwardly therefrom without the need of any suction forces of any mechanical means to be utilized with respect thereto.
- the treatment fluid 22 as seen in FIG. 1 from the treatment fluid supply means enters the work site 116, to keep the eye inflated, by gravity feed.
- the fluid is shown as delivered through the tool 14 it may be so delivered by a separate tube in a spaced apart relation to the tool member 14 or in a tube co-axially mounted within or against the tool member 14 from the same or different incision.
- the tool member may be within the anterior chamber with lavage occurring from about 1 minute to 45 minutes with treatment fluid in the range of 50cc to 1,000cc used. During this time the aggregate total time of vibration of the tool member may be from 5 seconds to 5 minutes, but applied on an intermittent basis.
- the treatment fluid 22 is supplied from the reservoir of a chemical solution of appropriate type and suitable for its intended use.
- the fluid also acts to keep the anterior chamber hydraulically inflated to maintain its shape during the surgical procedure.
- the switch 40 provided is to enable the control of the generator 30 such as to permit the user appropriate control during the surgical procedure.
- the switch 40 may be of any convenient type, preferably resting on the floor so as to permit the user to be able to use his foot to actuate same thereby permitting both hands of the user free to perform the necessary operation.
- the instrumentation 12 is used for the removal of an object or substance which is generally of a combined mass of undesired tissue located within the region of healthy tissue below the skin.
- the small surgical incision 112 is made through the cornea adjacent to the enclosed cataract mass 102 to enable the operative output edge or tip 15 of the handpiece 12 to reach the tissue mass 102.
- the surgeon actuates the switch 40 to power the generator and in turn the ultrasonic motor 45 is vibrated and the high frequency mechanical vibrations are transmitted to the tip 15.
- the treatment supply means 20 in its open position such that as the operative tip 15 of the tool member 14 is brought into contact with the mass 102 the operative tip 15 vibrates at a high frequency rate and with a small amplitude against the tissue mass 102 and concurrently, the treatment fluid supply 22, which is preferably selected of a type that is compatible with the animal tissue being treated such as saline fluids, baths the work site region 116 at the tip and which is being subjected to the vibratory motion.
- the surgeon having attained this status is now ready to commence the cataract removal technique developed by applicant in that the surgeon initially allows the ultrasonic to essentially pull the tip 15 into the mass 102 a defined length which is related to the size and hardness of the cataract and as seen particularly in FIGS.
- an initial bore or aperture 118 as seen in FIG. 5 is formed into the cataracts 102 and at that instant, it is believed certain amount of particles 115 tend to be broken away or shattered from the cataract 102 and these particles 102 flow into the anterior chamber 101 and thereafter find their way along the tool shank 55 and exit from the incision 112 as the fluid is continued to be supplied through the tool member 14.
- the work site 116 continues to be flooded or bathed with the treatment fluid and as the ultrasonic energy engages the cataract 102 then at the operative site 116, particles 115 of removed tissue in the treatment fluid and the particles 115 exit from the incision 112.
- the unwanted tissue thus separated from the cataract body is removed as it is broken apart and the effect of the initial bore is to in effect reduce the mass of the cataract.
- the surgeon then retracts the tool member 14 from the cataract 102 but not the incision 112 and as seen particularly in FIG. 5, thereafter drills a second bore 118 while the cataract is essentially fixed in position.
- the two additional bores 118 are formed into the cataract mass 102 which in effect causes a reduction in volume of the total mass and a shrinking of the size of the cataract such that in a sense it may be angularly rotated in the direction of arrow 120 to expose another portion of the cataract 102 to the incision 112.
- the surgeon can easily manipulate the handpiece 12 as required to work in the operative site 116 until the cataract is broken apart or is deformed so as to flow itself through the incision 112 and removed therefrom. If necessary, additional small incisions may be made at various other surface points to permit ready access to the mass 102 of unwanted tissue. However. each of these incisions need be only sufficiently large to permit the slender operative tip of the instrument to enter. The smaller the number of incisions made, the less will the trauma be and therefore the shorter the recovery time as compared to a massive excision by other procedures.
- the third bore 118 is being formed by the surgeon and thereafter the cataract I02 due to its reduced mass tends to shrink away from its surrounding walls and is free to be rotated as illustrated by arrow 120 in FIG. 7; i.e., 90, in the plane as seen in FIG. 3.
- the surgeon thereafter angularly rotates the cataract 102, if necessary, through a specific angle as particularly seen in FIG. 7, this is illustrated at approximately 90.
- the physical rotation of the cataract may be conducted with the tip 15 of the tool 14, the fluid flow, or with another surgical instrument elected by the surgeon. Once the completion of the angular rotation has been accomplished, then the surgeon may thereafter commence the drilling of additional bores 118 as seen particularly in FIG. 8 where three additional bores are illustrated.
- the result of this crossboring or drilling through the cataract in effect reduces the cataract into a plurality of sub-masses or larger particles 125 which are generally each too large to fit between the spacing defined by the outer surface of the tool member 14 and the incision 112. Therefore, we are left forthe moment with a number of submasses 125 that the surgeon now has to remove from the operative site in order to complete the surgical procedure. Since no suction is necessarily utilized, the surgeon then has the task of reducing the sub-masses 125 to particles for their removal.
- the surgeon positions the tip 15 of the tool member 14 against a sub-mass and energizes the tip 15 to the point such that it vibrates and the vibratory energy is then transmitted to the sub-mass 125, in effect tapping it at a rate of 30,000 cycles per second such that this continuous series of blows or tapping by the mechanical tool causes a further fracturing of the sub-particles 125 such that it may be reduced to the form of a particle 115 which particles thereafter are capable of exiting in the fluid bath created from the incision 112.
- This fluid bath continues to fill the anterior chamber 101 and they flow therein until engaged with the ultrasonic mechanical vibrations so that their size is reduced and thereafter exit from the incision 112.
- the surgeon may progressively, while working under a microscope, reposition the tool to abut or contact a mass and as same is positioned, is energized, through the switch, the vibratory tip 15 is vibrated for effecting further breaking down of each mass 125 into a particle size 115.
- the fluid supply under atmospheric pressure, such that it has a gravity feed under a hydrostatic pressure produced by a fluid column, then there is a continuous flushing away that is generated such that the particles 115 once broken away from the sub-mass 125 or mass 102 tend to be carried in this fluid stream that is created always flowing towards the incision 112 from which the fluid is exiting.
- FIGS. 3-10 illustrate the basis by which there is initially a forming of several bores through the cataract from the singular incision until the cataract mass has been sufficiently reduced in size and therefore is freely rotatable and thereafter due to the additional bores created there may be essentially a fracturing of the cataract into a number of smaller submasses.
- the actual fracturing is somewhat dependent upon the hardness of the cataract and for a softer cataract it is appreciated that the actual removal process is somewhat different than for a harder cataract.
- the initial drilling is performed as illustrated in FIGS.
- the incision 112 is maintained in an open state by the surgeon applying the necessary force by gripping the appropriate portion of the eye with the tweezer 106 as the surgeon 128 applies the necessary force to maintain the open position of the incision 112.
- a novel aspect of the present invention is seen in the ability of particles 115, sub-masses 125, or cataract mass 102 which have a larger volume or cross-section than the space defined between the outer surface 70 of the tool member 14 and the incision 112 to escape therethrough.
- the ability of the mass to more or less squeeze its way out of an opening by changing its width in the constricted area between the incision wall 114 and the tool member 14. Since the particle is not of a completely hard surface that has no flexibility, there is this wiggling," shrinking or moulding at its respective section which as seen in FIGS. 11-14 is progressive such that it creeps out through the opening 112 and carried in the fluid flow that has been created in the area.
- the sub-mass 125 due to the fluid flow initially positions itself such that its leading edge 130 abuts the incision 112 while the tool member 14 is not vibrated. The complete removal of the mass may occur without any vibration because of the pressure within the anterior chamber by the fluid flow. Also the surgeon viewing the sub-mass 125 reaching the position as seen in FIG.
- the microscope 11 through the microscope may energize the circuitry such that the tip 115 starts to vibrate as indicated by arrow 46 such that there is what is believed to be a viscosity reduction effect or reduction of friction effect a known phenomena of ultrasonic mechanical vibrations such that between the outer of surface 70, the tool member 14 and the incision wall 114, the leading edge 130 of the sub-mass 125 continues its creeping motion" until it progressively exits from its captivity as seen in FIG. 13 and thereafter as seen in FIG. 14 has fully left the confines of the eye. This step is repeated until the other masses 125 which cannot freely exit from the eye are freed of their captivity.
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Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US00318429A US3857387A (en) | 1972-12-26 | 1972-12-26 | Ultrasonic cataract removal method and apparatus |
IT51865/73A IT996100B (it) | 1972-12-26 | 1973-08-06 | Dispositivo ultrasonico per la rimo zione di tessuti cellulari |
FR7330641A FR2211206A1 (it) | 1972-12-26 | 1973-08-23 | |
JP48094486A JPS4989983A (it) | 1972-12-26 | 1973-08-24 | |
DE19732342922 DE2342922A1 (de) | 1972-12-26 | 1973-08-24 | Verfahren und vorrichtung zur entfernung eines grauen stars mittels ultraschall |
US05/496,565 US3942519A (en) | 1972-12-26 | 1974-08-12 | Method of ultrasonic cryogenic cataract removal |
US05/516,211 US3952732A (en) | 1972-12-26 | 1974-10-21 | Ultrasonic cataract removal method and apparatus |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US00318429A US3857387A (en) | 1972-12-26 | 1972-12-26 | Ultrasonic cataract removal method and apparatus |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US05/496,565 Continuation-In-Part US3942519A (en) | 1972-12-26 | 1974-08-12 | Method of ultrasonic cryogenic cataract removal |
US05/516,211 Division US3952732A (en) | 1972-12-26 | 1974-10-21 | Ultrasonic cataract removal method and apparatus |
Publications (1)
Publication Number | Publication Date |
---|---|
US3857387A true US3857387A (en) | 1974-12-31 |
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ID=23238156
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US00318429A Expired - Lifetime US3857387A (en) | 1972-12-26 | 1972-12-26 | Ultrasonic cataract removal method and apparatus |
Country Status (5)
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---|---|
US (1) | US3857387A (it) |
JP (1) | JPS4989983A (it) |
DE (1) | DE2342922A1 (it) |
FR (1) | FR2211206A1 (it) |
IT (1) | IT996100B (it) |
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US4016882A (en) * | 1975-03-05 | 1977-04-12 | Cavitron Corporation | Neurosonic aspirator and method |
US4169984A (en) * | 1976-11-30 | 1979-10-02 | Contract Systems Associates, Inc. | Ultrasonic probe |
US4184491A (en) * | 1977-08-31 | 1980-01-22 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Intra-ocular pressure normalization technique and equipment |
US4314560A (en) * | 1979-11-28 | 1982-02-09 | Helfgott Maxwell A | Powered handpiece for endophthalmic surgery |
US4320761A (en) * | 1979-02-06 | 1982-03-23 | Haddad Heskel M | Surgical device for excision of tissue |
US4363326A (en) * | 1980-12-22 | 1982-12-14 | Advanced Diagnostic Research Corporation | Ultrasonic apparatus for needle insertion |
US4531934A (en) * | 1982-04-13 | 1985-07-30 | Gorkovsky Gosudarstvenny Meditsinsky Institute Imini S.M. Kirova | Apparatus for the fragmentation and aspiration of ocular tissue |
US4597388A (en) * | 1983-12-15 | 1986-07-01 | Trutek Research, Inc. | Apparatus for removing cataracts |
US4634420A (en) * | 1984-10-31 | 1987-01-06 | United Sonics Incorporated | Apparatus and method for removing tissue mass from an organism |
US4689040A (en) * | 1985-04-29 | 1987-08-25 | Thompson Robert J | Tip for a phacoemulsification needle |
US4732150A (en) * | 1984-06-14 | 1988-03-22 | Keener Jr Gerald T | Process for cataract extraction |
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Also Published As
Publication number | Publication date |
---|---|
IT996100B (it) | 1975-12-10 |
JPS4989983A (it) | 1974-08-28 |
FR2211206A1 (it) | 1974-07-19 |
DE2342922A1 (de) | 1974-06-27 |
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