US3838065A - Standard solution of glycerol - Google Patents
Standard solution of glycerol Download PDFInfo
- Publication number
- US3838065A US3838065A US00279116A US27911672A US3838065A US 3838065 A US3838065 A US 3838065A US 00279116 A US00279116 A US 00279116A US 27911672 A US27911672 A US 27911672A US 3838065 A US3838065 A US 3838065A
- Authority
- US
- United States
- Prior art keywords
- glycerol
- standard solution
- solution
- standard
- perchloric acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 title abstract description 111
- 239000012086 standard solution Substances 0.000 title abstract description 10
- VLTRZXGMWDSKGL-UHFFFAOYSA-N perchloric acid Chemical compound OCl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-N 0.000 abstract description 18
- 238000004458 analytical method Methods 0.000 abstract description 3
- 239000000243 solution Substances 0.000 description 13
- PXIPVTKHYLBLMZ-UHFFFAOYSA-N Sodium azide Chemical compound [Na+].[N-]=[N+]=[N-] PXIPVTKHYLBLMZ-UHFFFAOYSA-N 0.000 description 6
- 239000000126 substance Substances 0.000 description 5
- 238000012544 monitoring process Methods 0.000 description 3
- 238000005259 measurement Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000000087 stabilizing effect Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/108331—Preservative, buffer, anticoagulant or diluent
Definitions
- the present invention is concerned with a glycerol standard solution and a method for the monitoring and control of glycerol determinations using such a solution.
- glycerol is stabilized to an outstanding extent by dilute perchloric acid solutions so that, even after storage for several months, no changes in the glycerol content of the standard glycerol solutons occur.
- a glycerol standard solution which consists of a solution of glycerol in 0.02 to 0.2 N perchloric acid, the solvent preferably consisting of approximately 0.05 N perchloric acid.
- the glycerol content is itself not critical but the solution is preferably sufficiently dilute in order to insure 3,838,065 Patented Sept. 24, 1974 exact measurement thereof. From this point of view, the preferred glycerol concentration is between about 1 mg./ ml. and 50 mg./ 100 ml. and is more preferably about 10 mg./l00 ml.
- the stabilizing action of the dilute perchloric acid ascertained according to the present invention is surprising because substances known to be outstanding stabilizing or preserving agents, such as sodium azide, have proved to be useless.
- the glycerol content When using a sodium azide solution, the glycerol content has already dropped after four weeks to such an extent that it can no longer be used as a standard solution and after ten Weeks storage, the glycerol content has, under these conditions, already decreased to about one half of the initial content.
- a glycerol standard solution consisting essentially of a solution of glycerol in 0.02 to 0.2 N perchloric acid, wherein the glycerol is present in an amount of from about 1 to 50 mg./100 ml.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2145346A DE2145346C3 (de) | 1971-09-10 | 1971-09-10 | Glycerin-Standardlösung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| US3838065A true US3838065A (en) | 1974-09-24 |
Family
ID=5819222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US00279116A Expired - Lifetime US3838065A (en) | 1971-09-10 | 1972-08-09 | Standard solution of glycerol |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3838065A (enrdf_load_stackoverflow) |
| JP (1) | JPS5327954B2 (enrdf_load_stackoverflow) |
| CH (1) | CH565127A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2145346C3 (enrdf_load_stackoverflow) |
| FR (1) | FR2152224A5 (enrdf_load_stackoverflow) |
| GB (1) | GB1345495A (enrdf_load_stackoverflow) |
| IT (1) | IT962412B (enrdf_load_stackoverflow) |
| NL (1) | NL168335C (enrdf_load_stackoverflow) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3891573A (en) * | 1973-05-14 | 1975-06-24 | Boehringer Mannheim Gmbh | Aqueous cholesterol standard solution |
| US4405817A (en) * | 1981-04-30 | 1983-09-20 | The B. F. Goodrich Company | Stabilized hydroxyl terminated reactive liquid polymers |
| US20110185893A1 (en) * | 2008-03-20 | 2011-08-04 | Donaldson Company, Inc. | Evacuation Valve Arrangements; Pulse Jet Air Cleaner Systems Using Same; and, Methods |
| US9186612B2 (en) | 2010-01-22 | 2015-11-17 | Donaldson Company, Inc. | Pulse jet air cleaner systems; evacuation valve arrangements; air cleaner components; and, methods |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5778808U (enrdf_load_stackoverflow) * | 1980-10-31 | 1982-05-15 |
-
1971
- 1971-09-10 DE DE2145346A patent/DE2145346C3/de not_active Expired
-
1972
- 1972-07-04 IT IT26595/72A patent/IT962412B/it active
- 1972-08-04 NL NLAANVRAGE7210699,A patent/NL168335C/xx not_active IP Right Cessation
- 1972-08-09 US US00279116A patent/US3838065A/en not_active Expired - Lifetime
- 1972-09-04 JP JP8858472A patent/JPS5327954B2/ja not_active Expired
- 1972-09-06 CH CH1308172A patent/CH565127A5/xx not_active IP Right Cessation
- 1972-09-06 GB GB4124572A patent/GB1345495A/en not_active Expired
- 1972-09-08 FR FR7231897A patent/FR2152224A5/fr not_active Expired
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3891573A (en) * | 1973-05-14 | 1975-06-24 | Boehringer Mannheim Gmbh | Aqueous cholesterol standard solution |
| US4405817A (en) * | 1981-04-30 | 1983-09-20 | The B. F. Goodrich Company | Stabilized hydroxyl terminated reactive liquid polymers |
| US20110185893A1 (en) * | 2008-03-20 | 2011-08-04 | Donaldson Company, Inc. | Evacuation Valve Arrangements; Pulse Jet Air Cleaner Systems Using Same; and, Methods |
| US8262762B2 (en) | 2008-03-20 | 2012-09-11 | Donaldson Company, Inc. | Evacuation valve arrangements; pulse jet air cleaner systems using same; and, methods |
| US9186612B2 (en) | 2010-01-22 | 2015-11-17 | Donaldson Company, Inc. | Pulse jet air cleaner systems; evacuation valve arrangements; air cleaner components; and, methods |
| US10675578B2 (en) | 2010-01-22 | 2020-06-09 | Donaldson Company, Inc. | Pulse jet air cleaner systems; evacuation valve arrangements; air cleaner components; and, methods |
| US11826691B2 (en) | 2010-01-22 | 2023-11-28 | Donaldson Company, Inc. | Pulse jet air cleaner systems; evacuation valve arrangements; air cleaner components; and, methods |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2145346A1 (de) | 1973-04-19 |
| DE2145346C3 (de) | 1978-03-09 |
| FR2152224A5 (enrdf_load_stackoverflow) | 1973-04-20 |
| JPS4838192A (enrdf_load_stackoverflow) | 1973-06-05 |
| NL168335C (nl) | 1982-03-16 |
| NL168335B (nl) | 1981-10-16 |
| DE2145346B2 (de) | 1977-07-14 |
| CH565127A5 (enrdf_load_stackoverflow) | 1975-08-15 |
| JPS5327954B2 (enrdf_load_stackoverflow) | 1978-08-11 |
| NL7210699A (enrdf_load_stackoverflow) | 1973-03-13 |
| IT962412B (it) | 1973-12-20 |
| GB1345495A (en) | 1974-01-30 |
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