US3815577A - Bacterial seals - Google Patents

Bacterial seals Download PDF

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Publication number
US3815577A
US3815577A US00270458A US27045872A US3815577A US 3815577 A US3815577 A US 3815577A US 00270458 A US00270458 A US 00270458A US 27045872 A US27045872 A US 27045872A US 3815577 A US3815577 A US 3815577A
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United States
Prior art keywords
sleeve means
exterior
elongated member
combination
sleeve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US00270458A
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English (en)
Inventor
L Bucalo
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Investors in Ventures Inc
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Investors in Ventures Inc
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Filing date
Publication date
Application filed by Investors in Ventures Inc filed Critical Investors in Ventures Inc
Priority to US00270458A priority Critical patent/US3815577A/en
Priority to FR7408951A priority patent/FR2263791A1/fr
Priority to AU66954/74A priority patent/AU6695474A/en
Priority to DE2423338A priority patent/DE2423338A1/de
Application granted granted Critical
Publication of US3815577A publication Critical patent/US3815577A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/0247—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0004—Closure means for urethra or rectum, i.e. anti-incontinence devices or support slings against pelvic prolapse
    • A61F2/0009—Closure means for urethra or rectum, i.e. anti-incontinence devices or support slings against pelvic prolapse placed in or outside the body opening close to the surface of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/20—Vas deferens occluders; Fallopian occluders
    • A61F6/22—Vas deferens occluders; Fallopian occluders implantable in tubes
    • A61F6/24—Vas deferens occluders; Fallopian occluders implantable in tubes characterised by valve means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A61L27/047—Other specific metals or alloys not covered by A61L27/042 - A61L27/045 or A61L27/06
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/0247—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body
    • A61M2039/0261—Means for anchoring port to the body, or ports having a special shape or being made of a specific material to allow easy implantation/integration in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/0247—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body
    • A61M2039/027—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body having a particular valve, seal or septum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/0247—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body
    • A61M2039/0285—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body with sterilisation means, e.g. antibacterial coatings, disinfecting pads, UV radiation LEDs or heating means in the port

Definitions

  • ABSTRACT exterior surface of the elongated member and the interior surface of the sleeve Through this elongated member it is possible to have any desired type of communication between the exterior of the body and the internal space.
  • a barrier is located at the interface between the elongated member and the sleeve for preventing any bacteriological contamination of the interior body space from the exterior.
  • the present invention relates to' structures which will enable many different types of communication to be achieved between the exterior of a body and an interior space thereof while at the same time preventing bacterial contamination of the internal body space.
  • Yet another object of the present invention is to provide a construction of this type which is easily mounted in the human body while assuring a tight intimate and secure connection between the structure of the invention and the body of the living being.
  • an outer sleeve means is mounted within an openingin the body which extends from the exterior'of the body to an. internal space therein, this sleeve means carrying at its exterior a means for providing a tight secure connection between the sleeve means and the tissue of the body.
  • An elongated member is situated within and surrounded by the sleeve means and at the interface between the elongated member and the sleeve means there is an extremely close, precise fit obtained, for example, by initially depositing the sleeve means directly on the exterior surface of the elongated member.
  • the elongated member may be used for any number of purposes. For example it may form part of a valve for achieving incontinence control when the valve is situated in the male urethra, or it may be used toadjust a device implanted in the body. It may also be used for providing electrical communication between the exterior and interior of the body, or it may simply have a window to provide for visual observation of the interior body space.
  • FIG. 1 is a schematic partly sectional elevation of one embodiment .of the invention
  • FIG. 2 is a schematic partly sectional elevation of a second embodiment of the invention.
  • FIG. 3 is a schematic partly sectional elevation illustrating the manner in which the invention may be used for incontinence control
  • FIG. 4 is a schematic representation of one purpose which may be served by the structure of the invention.
  • FIG. 5 is a schematic top plan view of the structure of FIG. 4;
  • FIG. 6 is a partly sectional elevation of the structure of the invention illustrating a further manner in which it may be used.
  • FIG. 7 is a schematic representation of yet another use to which the structure of the invention may be put.
  • FIG. 1 there is schematically represented in FIG. 1 a wall of tissue 10 forming part of a human body, for example, and having an exterior surface 12 where the exterior skin of the human being is located.
  • the opposed surface 14 of the wall 10 forms part of any internal space of the human body, or the body of an animal, if desired.
  • the surface 14 may form part of an elongated body passage through which a fluid flows or it may form part of the interior of an'organ of the human body.
  • the wall M) of the human body is formed with an opening 16 which is lined with a sleeve means 18 which carries at its exterior surface a means 20 for providing a tight, intimate, and secure connection between the wall 10 and the sleeve means 18.
  • the sleeve 18 may be made of a material which is compatible with the body, such as gold, and the means 20 in the illustrated example takes the form of a fine gold wire which is wound around and engages the exterior .of the sleeve means 18. Instead of a single strand of wire which is wound several times around the exterior of the sleeve 18 it is possible to use a fine gold wire mesh, for example.
  • the means 20 provides 'a large number of interstices into which the tissue 10 grows to provide the tight, intimate and secure connection between the sleeve means 18 and the wall 10 in the opening 16 thereof.
  • An elongated member 22 extends through the sleeve means 18 and is turnable therein.
  • This elongated member 22 has an extremely close, precise fit at the interface 24 between the elongated member 22 and the sleeve means 18.
  • the assembly of the elongated member 22 and the sleeve means 18 may be carried out in accordance with the teachings of US Pat. No. 3,616,520.
  • the elongated member 22 is made of a material to which the sleeve'means 18 will not adhere.
  • the material of the sleeve means 18 is deposited in' any number of different ways, such as electrolyti- 3 cally, directly on the exterior surface of the elongated member 22, and the deposition is continued until the desired thickness of the sleeve means 18 is achieved. In this way it is possible to provide the desired extremely close precise fit between the sleeve means 18 and the elongated member 22 while at the same time the latter is turnable within the sleeve means 18 and with respect thereto at the interface 24.
  • a barrier means 26 is provided to prevent bacterial communication between the exterior of the body at the skin 12 and the interior space which is defined in part by the inner surface 14 of the wall 10.
  • the barrier means 26 takes the form of an annular groove 28 formed in the elongated member 22 and a projection 30 forming part of the sleeve means 18.
  • This projection 30 is formed during deposition of the sleeve means 18 on the member 22 so that a correspondingannular groove 32 forms at the exterior of the sleeve 18 which has a uniform thickness due to the deposition of the sleeve means 18 on the-member 22.
  • This groove 32 provides further security in the connection between the sleeve means and the wall because the tissue of the latter will grow into the groove 32.
  • the projection 30 in the groove 28 will form a barrier through which bacteria cannot travel, so that in this way abacterial seal is achieved with the structure of FIG. 1.
  • the member 22 may be formed with a non-circular bore 34 extending partly into the member 22 along the axis thereof and capable of rcceiving a wrench, such as an-Allen wrench, so that through this structure it .is possible to turn the member 22 within the sleeve means 18 for any desired purpose.
  • FIG. 2 also illustrates the wall 10 having the exterior skin 12 and the interior surface 14 which forms part of an interior space of the body, and the opening 16 is also lined with a sleeve means 18 made of gold and having at its exterior surface a means in the form of wound gold wire or agold wire mesh to achieve the tight, intimate, secure connection between the sleeve means 18 and the wall 10.
  • the sleeve-means does not have an exterior flange, but of course this feature is immaterial.
  • an elongated member 40 which is also made, for example, of a material to which the gold will not adhere and on which the gold of the sleeve means 18 is directly deposited in a manner described above 'in connection with FIG. 1.
  • the elongated member 40 is formed with an annular groove 42 which-is filled with wax, for example, before the gold of the sleeve means 18 is deposited on the elongated member 40.
  • the member 40 is formed with a bore 44 which is internally threaded so that it can be closed by a 010- sure means such as a suitable set screw.
  • the bore 44 in turn communicatesthrough an inclined bore 46 with the groove 42.
  • the elongated member 40 may be formed with notches 48 so that the member 40 can be turned by a screwdriver, for example, for any desired purpose, as referred to below.
  • the wax is removed from the groove 42 by heating the member 40 so that the wax will melt and will flow out through the bore 46 and the internally threaded bore 44. Then, after the structure is mounted in the opening 16 in the manner shown in FIG. 2, or even before it is mounted therein, a suitable antibiotic material is situated within the annular groove 42 by introducing this antibiotic through the bore 44 and the inclined bore 46. The antibiotic can fill the groove 42 and can extend up the bore 46 to the bore 44, and then the latter can be closed with a suitable set screw.
  • the antibiotic in the groove 44 will form a barrier means preventing the travel of living bacteria past the groove 42.
  • FIG. 3 illustrates how the invention is used in connection with control of incontinence.
  • the outer sleeve means 50 is extended to form a valve housing.
  • the sleeve means 50 is again situated in an opening 16 in a wall 10 of the human body, this wall 10 in this case being part of a penis and being situated at the urethra 52.
  • the inner surface 14 forms part of the urethra.
  • Thesleeve means 50 is again covered at its exterior surface by the means 54 in the form of fine gold wire, or a wire mesh, providing the small interstices into which the tissue grows so as to provide the secure tight connection between the valve housing and the wall 10 as well as the part of the urethra 52 opposite from the wall 10, as illustrated.
  • the valve housing formed by the sleeve means 50 has an inlet opening 56 and an outlet opening 58 in the form of an elongated tube.
  • the elongated member of this embodiment takes the form of a rotary valve member 60, and the gold which forms the valve housing is deposited directly on the member 60 so as to provide the close precise fit referred to above.
  • the elongated member 60 in this case terminates at itsinner end in a rotary substantially spherical valve body 62 formed with the valve opening 64 extending diammetrically therethrough and having an axis situated at the elevation of the axis of the tubular outlet 58.
  • the elongated member or valve member 60 is shown in FIG. 3 in its closed position where the axis of the opening 64 extends perpendicularly with respect to the axis of the urethra passage 52.
  • the elongated member 60 is formed with a noncircular bore 66 capable of receiving a wrench, such-as an Allen wrench, as referred to above, so that it is possible to turn the valve member between the closed positionshown in FIG. 3 and an open position where the bore 64 will assume the dot-dash line position illustrated providing a clear passage continuously through the urethra. Therefore, in order to control incontinence it is possible to close the valve so as to prevent urine from flowing through the urethra, while at the same time it is possible whenever desired to place the valve in its open position permitting free flow of urine.
  • a wrench such-as an Allen wrench
  • the elongated member 60 is formed at its portion which forms the valve stem with an annular groove 68 which is filled with an antibiotic material '70.
  • the interior portion of the noncircular bore 66 is circular and internally threaded so as to receive a closure means in the form of a set screw 72.
  • the lower or interior end of the bore 66 communicates through the inclined bores 74 with theannular groove 68.
  • the embodiment of FIG. 3 is similar to that of FIG. 2, and of course when the structure of FIG.
  • this embodiment has the bacterial barrier means which prevents bacterial contamination of the interior of the body by travel of bacteria at the interface between the outer sleeve means 50 and the elongated member 60.
  • FIGS. 1 and 2 may be used in a number of different ways. As examples of possible uses thereof,
  • FIGS. 4-7 illustrate some applications.
  • FIG. 4 illustrates an embodiment similar to that of FIG. 1 where the inner end of member 22 is provided with an integral extension 80 terminating in a socket wrench type of cup 82.
  • the non-circular interior of the wrench or cup 82 receives a non-circular rotary adjusting member 84 of an implanted device 86 which may, for example, be a pacemaker.
  • the flange of the sleeve means 18 is extended beyond the outer periphery of the outer flanged end of the member 22. In this way it is possible to provide on the extended flange of member 18 an index 88, as illustrated in FIG. 5.
  • the outer flange end 90 of the member 22 is provided with graduations.
  • one of the graduations can be aligned with the index 88, and in this way it is possible to know the extent of adjustment of an implanted device such as the device 86 shown in FIG. 4.
  • FIGS. 4 and 5 it is possible while maintaining a bacterial seal to provide from the exterior of the body planted device and aligned with each other in such a way that turning of the exterior element will result in a corresponding turning of the interior element.
  • FIG. 6 illustrates a rotary member 40 corresponding in all respects to the member 40 of FIG. 2 and mounted in precisely the same way as described above in connection with FIG. 2 and as shown in FIG. 2.
  • the member 40 is formed with an elongated bore 94 passing therethrough and receiving elongated electrical conductors 96.
  • the interior of the bore 94 is sealed with any suitable sealing material which tightly closes the bore 94 while the sealing material closely surrounds the conductors 96 with the latter being embedded in the sealing material in the bore 94 so that there is not the possibility of bacterial contamination through the bore 94.
  • the outer portions of the conductors 96 can be connected to any suitable electrical device such as a meter, a potentiometer, a battery, etc., and the interior portions of the conductors 96 can be connected to any unit implanted within the body so thatwhile preventing bacterial communication it is possible in this way to achieve an electrical connection between the interior and exterior of the body.
  • the member 98 which is fragmentarily illustrated therein may take the form either of the member 40 of FIG. 2 or ofthe member 22 of FIG. 1,.with this member being mounted either as illustrated in FIG. 2 or as illustrated in FIG. 1.
  • the member 98 is formed with a bore 100 extending completely therethrough at a location wherethis bore will not interfere with an opening for a wrench, for example, or with an opening such as the recess 44 of FIG. 2 through which the supply of antibiotic may be replenished.
  • the bore 100 is tightly closed by a transparent plate 102 made of a material such as clear glass, a suitable plastic, or the like, with the outer periphery of the plate 102 being tightly fixed along its entire periphery to the inner surface of the bore 100 as by using a suitable glue or the like.
  • a transparent plate 102 made of a material such as clear glass, a suitable plastic, or the like, with the outer periphery of the plate 102 being tightly fixed along its entire periphery to the inner surface of the bore 100 as by using a suitable glue or the like.
  • FIGS. 4-7 illustrate some of the possible applications of the present invention.
  • the structure by which the elongated member is mounted in the opening of the body is exceedingly simple and at the same time provides a secure tight connection with the body tissue.
  • An exceedingly great safety with respect to prevention of bacterial contamination is achieved by way of the very close seal between the inner member and the sleeve means which surrounds the same, this seal being achieved by way of the deposited fit according to which the sleeve means is directly deposited on the elongated member so as to have the closest possible fit therewith.
  • the barrier means of the invention whether it takes the form of the tongue-and-groove type of barrier shown in FIG. 1 or the encapsulated antibiotic as shown in FIG. 2, will provide with the utmost reliability prevention of bacterial contamination.
  • outer sleeve means for lining a body opening extending from the exterior thereof to an internal body space, said sleeve means having opposed open ends respectively adapted to be situated at the exterior of the body and the internal body space and having an uninterrupted hollow interior extending between said opposed open ends, and said sleeve means carrying on its exterior surface-a means for providing a tight, sealed engagement between tissue of the body and the exterior surface of said sleeve means, an elongated member situated in and surrounded by said sleeve means, said elongated member having at an exterior surface thereof a close, precise fit in said sleeve means at an inner surface of said sleeve means which definesan interface with said exterior surface of said elongated member, and barrier means situated at said interface between said elongated member and sleeve means for preventing bacteriological communication between the exterior of the body and the internal space thereof to achieve a bacteriological seal.
  • said sleeve means forms a valve housing having openings situated in the body space, and said elongated member forming part of a valve member rotatable in said housing, the close fit between the latter and said valve member being sufficient to remove during turning of said valve member deposits which form on the exterior surface of said valve member through said housing openings.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Inorganic Chemistry (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Prostheses (AREA)
US00270458A 1972-07-10 1972-07-10 Bacterial seals Expired - Lifetime US3815577A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US00270458A US3815577A (en) 1972-07-10 1972-07-10 Bacterial seals
FR7408951A FR2263791A1 (cg-RX-API-DMAC10.html) 1972-07-10 1974-03-15
AU66954/74A AU6695474A (en) 1972-07-10 1974-03-21 Bacterial seals
DE2423338A DE2423338A1 (de) 1972-07-10 1974-05-14 Verschluss gegen das eindringen von bakterien

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00270458A US3815577A (en) 1972-07-10 1972-07-10 Bacterial seals

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US3815577A true US3815577A (en) 1974-06-11

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US00270458A Expired - Lifetime US3815577A (en) 1972-07-10 1972-07-10 Bacterial seals

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US (1) US3815577A (cg-RX-API-DMAC10.html)
AU (1) AU6695474A (cg-RX-API-DMAC10.html)
DE (1) DE2423338A1 (cg-RX-API-DMAC10.html)
FR (1) FR2263791A1 (cg-RX-API-DMAC10.html)

Cited By (23)

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US4015601A (en) * 1975-10-14 1977-04-05 General Atomic Company Blood access device
US4092983A (en) * 1977-01-31 1978-06-06 General Atomic Company Blood access device
US4108173A (en) * 1977-04-11 1978-08-22 General Atomic Company Blood access device
EP0003671A1 (en) * 1978-02-07 1979-08-22 Johnson & Johnson Stoma adaptor
US4186728A (en) * 1977-02-18 1980-02-05 U.S. Philips Corporation Apparatus for adapting a skull for the application of a pressure transducer
US4209010A (en) * 1978-07-26 1980-06-24 The Kendall Company Artificial sphincter
US4210132A (en) * 1978-07-26 1980-07-01 The Kendall Company Artificial sphincter
US4210131A (en) * 1978-07-26 1980-07-01 The Kendall Company Artificial sphincter with collection bag
US4265244A (en) * 1979-02-07 1981-05-05 Johnson & Johnson Stoma adaptor
US4318401A (en) * 1980-04-24 1982-03-09 President And Fellows Of Harvard College Percutaneous vascular access portal and catheter
US4344435A (en) * 1978-12-15 1982-08-17 Aubin Norbert T Method and surgically implantable apparatus for providing fluid communication with the interior of the body
EP0134340A1 (en) * 1983-08-22 1985-03-20 The University of Utah Research Foundation Peritoneal injection catheter apparatus
US4557724A (en) * 1981-02-17 1985-12-10 University Of Utah Research Foundation Apparatus and methods for minimizing cellular adhesion on peritoneal injection catheters
US4753656A (en) * 1986-01-21 1988-06-28 Tofield Joshua J Method and apparatus for securing a prosthesis to the human body
EP0379962A1 (de) * 1989-01-21 1990-08-01 Heinz Kurz Einsatzteil zur Belüftung des Mittelohrraumes
WO1994025081A1 (en) * 1991-01-07 1994-11-10 Menaker Gerald J Method and means for limiting thromboses in implantable grafts and the like
US5728103A (en) * 1996-08-23 1998-03-17 Applied Medical Technology, Inc. Implantable subcutaneous access device and method of using same
WO1998044967A1 (de) * 1997-04-04 1998-10-15 Mediport Biotechnik Gmbh Abdichtvorrichtung für ein in einen menschlichen oder tierischen körper einzuführendes hautdurchleitungselement
US20030023208A1 (en) * 2001-07-24 2003-01-30 Osypka Thomas P. Apparatus for vascular access
EP1596759A4 (en) * 2003-02-04 2006-07-19 Imagine Enterprise Inc ARTIFICIAL RECTUM AND RELATED METHOD
US7468050B1 (en) 2002-12-27 2008-12-23 L. Vad Technology, Inc. Long term ambulatory intra-aortic balloon pump
US20160101275A1 (en) * 2014-10-08 2016-04-14 Alfred E. Mann Foundation For Scientific Research Percutaneous Ports with Wire Coils
US10086184B2 (en) 2014-10-08 2018-10-02 Alfred E. Mann Foundation For Scientific Research Method of manufacturing percutaneous ports with wire coils

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DE2967214D1 (en) * 1978-10-10 1984-10-18 Ici Plc Product adapted for transcutaneous use

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US3216420A (en) * 1962-12-27 1965-11-09 Marvin E Claycomb Colostomy attachments
US3402710A (en) * 1966-06-27 1968-09-24 Hydra Power Corp Self-closing valve device for implantation in the human body
US3447161A (en) * 1966-08-01 1969-06-03 Avco Corp Disinfectant dispensing percutaneous connector
DE1961531A1 (de) * 1968-12-09 1970-07-09 Aga Ab Implantables Befestigungsmittel fuer Prothesen u.dgl.
US3687129A (en) * 1970-10-02 1972-08-29 Abcor Inc Contraceptive device and method of employing same
US3704704A (en) * 1970-10-12 1972-12-05 Ramon L Gonzales Birth control valve

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3216420A (en) * 1962-12-27 1965-11-09 Marvin E Claycomb Colostomy attachments
US3402710A (en) * 1966-06-27 1968-09-24 Hydra Power Corp Self-closing valve device for implantation in the human body
US3447161A (en) * 1966-08-01 1969-06-03 Avco Corp Disinfectant dispensing percutaneous connector
DE1961531A1 (de) * 1968-12-09 1970-07-09 Aga Ab Implantables Befestigungsmittel fuer Prothesen u.dgl.
US3687129A (en) * 1970-10-02 1972-08-29 Abcor Inc Contraceptive device and method of employing same
US3704704A (en) * 1970-10-12 1972-12-05 Ramon L Gonzales Birth control valve

Cited By (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4015601A (en) * 1975-10-14 1977-04-05 General Atomic Company Blood access device
FR2327800A1 (fr) * 1975-10-14 1977-05-13 Gen Atomic Co Dispositif pour permettre l'acces a un systeme circulatoire d'un organisme vivant avec canalisation et robinet d'arret
US4092983A (en) * 1977-01-31 1978-06-06 General Atomic Company Blood access device
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Also Published As

Publication number Publication date
AU6695474A (en) 1975-09-25
FR2263791A1 (cg-RX-API-DMAC10.html) 1975-10-10
DE2423338A1 (de) 1975-11-27

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