US3777742A - Tantalum insufflator - Google Patents

Tantalum insufflator Download PDF

Info

Publication number
US3777742A
US3777742A US00289836A US3777742DA US3777742A US 3777742 A US3777742 A US 3777742A US 00289836 A US00289836 A US 00289836A US 3777742D A US3777742D A US 3777742DA US 3777742 A US3777742 A US 3777742A
Authority
US
United States
Prior art keywords
chamber
line
inlet
outlet
inlet line
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US00289836A
Other languages
English (en)
Inventor
C Aumiller
L Morrison
D Holinbeck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Barber Colman Co
Kenner Parker Toys Inc
Liebel Flarsheim Co LLC
Original Assignee
Barber Colman Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Barber Colman Co filed Critical Barber Colman Co
Application granted granted Critical
Publication of US3777742A publication Critical patent/US3777742A/en
Assigned to KENNER PARKER TOYS INC. reassignment KENNER PARKER TOYS INC. CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: CPG PRODUCTS CORP.
Assigned to LIEBEL-FLARSHEIM COMPANY reassignment LIEBEL-FLARSHEIM COMPANY ASSIGNMENT OF ASSIGNORS INTEREST. Assignors: SYBRON CORPORATION, A CORP OF NY.
Assigned to GREAT AMERICAN INSURANCE COMPANY, A CORP OF OH reassignment GREAT AMERICAN INSURANCE COMPANY, A CORP OF OH SECURITY INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: LIEBEL-FLARSHEIM COMPANY, A DE CORP
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/0813—Measurement of pulmonary parameters by tracers, e.g. radioactive tracers

Definitions

  • ABSTRACT Apparatus for insufflating the airways of a patient with tantalum dust, either by the inhalation method or the catheter method.
  • This invention relates to apparatus for insufflating the airways of a human with a radiopaque powder, such as powdered tantalum, for the purpose of preparing the airways for radiologic study.
  • insufflation of tantalum may be effected either by a catheter method or by an inhalation method, and in each instance, a cloud of tantalum dust is generated by blowing air into a pile of powdered tantalum stored in a chamber defined within a container.
  • the catheter method the tantalum dust in the cloud is .blown from the chamber and into the airways of the patient via a catheter tube while, with the inhalation method, the dust is sucked into the airways as the patientinhales on a tube leading from the chamber.
  • the inhalation method is preferred in most casesin order to avoid the need for a catheter but it is sometimes necessary to use a catheter if it is desired to outline a particular area of the bronchus or with infantsor patients who, may not be completely healthy.
  • the general aim of the present invention is to provide new and improved apparatus which isparticularly suitable for insufflating by the inhalation method and which is characterized by its ability to generatea dust cloud in the chamber without forcing the dust out of thechamber so as to avoid the escape of dust when the patient is not inhaling.
  • a more detailed object is to use pressurized air to generate the dust cloud in the chamber while keeping the chamber itself unpressurized to prevent the dust from escaping from the chamber except when the patient inhales.
  • the invention also resides in the provision of new and improved insufflating apparatus with an insufflatingair circuit and a closed loop cloud generating air circuit, the two circuits coacting to accomplish effective tantalum insufflation by the inhalation method.
  • a further object ofthe invention is to provide unique apparatus which may be used to insufflate the airways either bythe inhalation method or the catheter method.
  • the invention is further characterized by several advantageous features which insure proper insufflation of the patient and assist in the proper administration of the tantalum.
  • FIG. 1 is a schematic view of new and improved in sufflatin g-appar atus embodying the novel features of the present invention.
  • FIG. 2 is a top plan view of the tantalum container.
  • FIG. 3 is afragmentary cross-section taken substantially along the line 3-3 of FIG. 2.
  • the invention is embodied in apparatus for insufflating the airways of a patient with powdered tantalum or similar radiopaque powder preparatory to taking a bronchogram.
  • the tantalum powder or dust varies in size from zero to five microns or larger, is non-toxic and serves to line and suitably opacify the airways.
  • a pile 10 of tantalum powder is placed in the lower end of a chamber 11 de? fined within an upright vessel or container 13 formed with a downwardly tapered frusto-co'nical body 14, a
  • the dust cloud is effectively generated in the chamber 11 by blowing pressurized air against the pile of tantalum powder but, at the same time, is created without producing positive pressure in the chamber so as to avoid blowing the powder out of the outlet line 20 when the patient is not inhaling.
  • a dense dust cloud may be continuously generated in the chamber while the patient is being prepared forinsufflation and yet the dust will not flow out of or escape from the chamber until the patient actually sucks through the outlet line.
  • a cloud generating circuit 21 and an insufflating or inhalation circuit 23 (FIG. 1) to enable creation of the tantalum dust cloud in the chamber 11 without positive pressure and to enable the patient to suck from the chamber a stream of tantalum-laden air.
  • the inhalation circuit 23 includes the outlet line 20, which extends downwardly into the chamber 11 through the top plate 17 as shown in FIG. 3,and further includes an inlet line 24 whose downstream end also communicates with the chamber through the top plate.
  • the upstream end of the inlet line 24 is adapted to communicate with the atmosphere and thus, when the patient sucks on the outlet line 20, a stream of air is drawn into the chamber from the inlet line and flows through the chamber and into the outlet line for delivery into the lungs of the patient.
  • the cloud generating circuit 21 includes a power driven pressure pump 30, such as a diaphragm pump, whose discharge side is connected to an outlet conduit 31 (FIGS. 1 and 3) extending downwardly into the chamber 11 and terminating in a generally cylindrical nozzle 33 disposed immediately above the pile of powder.
  • a power driven pressure pump 30 such as a diaphragm pump
  • the nozzle is formed with one centrally located and vertically extending hole 34 (FIG. 4) and with a series of angularly spaced holes 35 which are inclined downwardly and outwardly.
  • a pressure regulator 37 (FIG. 1) preferably is placed in the outlet conduit 31 to enable selective controlof the turbulence created above the dust pile.
  • the latter is connected detachably to the cover plate 17 by a bayonet connection indicated generally at 39 in FIGS. 3 and 5 and thus the container may be turned and pulled downwardly away from the cover plate.
  • the container may be loaded through the outlet line 20 with the aid of a funnel or the like.
  • the cloud generating circuit 21 (FIG. 1) includes an inlet conduit 40 whose one end is connected to the suction side of the pump and whose other end communicates with the chamber 11 by way of a T-fitting 41 in the inlet line 24.
  • the cloud generating circuit.2l consists of the pump 30, the outlet conduit 31, the chamber 11 and the inlet conduit 40 and thus forms a closed loop which extends through the chamber.
  • the chamber is not pressurized to any substantial extent when -the pump is operated to form the dust cloud but, instead, that quantity of air which is discharged into the chamber through the outlet conduit 31 is removed from the chamber and returned to the pump through the inlet conduit 40.
  • the chamber thus remains at substantially atmospheric pressure in spite of the air jets being discharged from the nozzle 33 and hence the tantalum dust is conserved and is not blown through the outlet line 20 when thepatient is not inhaling.
  • some ofthe dustparticles in the cloud become entrained in the air stream being drawn into the chamber 11 through the inlet line 24 and are sucked through the outlet line and into the airways of the patient.
  • the outlet line 20, the inlet line 24 and the outlet conduit 31 are positioned in such a manner as to create a long flow path for the inhaled stream of air through the tantalum cloud.
  • the outlet conduit 31 extends downwardly through the center of the top plate 17 (see FIGS. 2 and 3) while the outlet line 20 and the inlet line 24 are located on opposite sides of the outlet conduit.
  • the inlet line 24 terminates at the top plate 17 but the outlet line 20 extends well downwardly into the container 13 as shown in FIG. 3.
  • Air being discharged from the centrally located outlet conduit 31 tends to create a turbulent swirl of dust in the chamber 11 and, because of the angular and vertical spacing between the outlet line 20 and the inlet line 24, the inhaled stream of air tends to flow along a comparatively long path as the stream moves through the chamber (see the arrows in FIG. 3). As a result of the long flow path, more of the tantalum dust becomes entrained in the inhaled stream.
  • the preferred apparatus includes several advantageous features which insure proper insufflation of the patient and assist in the proper admistration of the tantalum.
  • a throttle valve 45 (FIG. 1) is located in the upstream end portion of the inlet line 24 and may be adjusted to regulate the volume of air which the patient may inhale.
  • a desiccator 46 Located in the inlet line downstream of the throttle valve is a desiccator 46 containing a suitable drying agent such as calcium sulfate for removing moisture from the inhaled air so as to prevent a moisture build up in the chamber 11 and reduce caking of the tantalum and bacterial contamination of the chamber.
  • a suitable drying agent such as calcium sulfate
  • a flow meter 47 with a peak flow indicator 49 Downstream of the desiccator is a flow meter 47 with a peak flow indicator 49, and associated with the flow meter is a resettable total volume indicator 50 which enables the radiologist to determine the total amount of tantalum-laden air which has been inhaled by the patient at any given time.
  • a biological filter 53 (FIGS. 1 and 2) is located in the inlet line 24 just downstream of the T-fitting 41 and just above the cover plate 17 of the chamber 11. As the patient inhales the filter catches any foreign particles larger than one micron so as to clean the air inhaled through the line 24 before such air reaches the patients airways. In addition, the filter collects tantalum dust which otherwise would be sucked upwardly from the chamber into the inlet conduit 40 and the cloud generating pump 30. When the patient inhales, the ,air being sucked downwardly through the filter tends to clear the latter by returning the collected tantalum back to the chamber.
  • a filter which is suitable for these purposes is sold by Ohio Medical Products under part designation 225-2605-700.
  • the dust cloud is formed primarily in the lower two-thirds of the chamber at a location remote from the filter 53 and the downstream or open end of the inlet line 24. Accordingly, less tantalum is sucked into the filter than otherwise would be the case if the cloud formation were concentrated near the top of the chamber.
  • Means 55 are provided for vibrating off of the interior surfaces of the container 13 that tantalum which collects on the surfaces during generation of the dust cloud.
  • these means comprise a power-driven hammer '56 (FIG. 5) which repeatedly raps against the cover plate 17 of the container 13 to shake the latter and shear away the tantalum which collects on the container surfaces.
  • the hammer 56 (FIG. 5) comprises a headed bolt which is threaded into the free end of an arm 57 whose other end is pivoted at 59 for up and down swinging on a bracket 60 upstanding from a mounting plate 61fastened to and supporting the cover plate 17.
  • An electric motor 63 (FIGS. 2 and 5) also is supported on the mounting plate and its drive shaft 64 rotates a wheel 65 at a rate of about rpm.
  • Carried on the wheel in radially offset relation with the shaft 64 is a pin 66 which is adapted to underlie a pad 67 secured to and projecting from one side of the arm 57 and adjustable lengthwise along the arm. As the wheel is rotated clockwise from the position shown in FIG. 5,
  • the pin 66 swings the arm 57 upwardly to raise the hammer 56 away from the cover plate l7.Then, when the pin clears the pad 67, the arm swings downwardly under the influence of a series of weights 69 supported on a stud 70 upstanding from the arm. As the arm swings downwardly, the hammer strikes an anvil 71 on the cover plate 17 and thus vibrates the container 13 to shaflce the tantalum loose from the container walls. Becausethe hammer strikes the cover plate of the container, the bond between the tantalum and the container side walls is broken in shear and thus the tantalum is removed more effectively than otherwise would be'the case if the hammer stuck against the side of the container.
  • the vibration effected by the hammer also shakes the filter to cause the tantalum collected thereon ,to fall back into the container.
  • the' conical walls of the body 14 of the container serve to funnel the dust back into the tantalum pile stored in the cylindrical bottom portion 15 of the container.
  • the frequency with which the hammer 56 vibrates the container 13 may be changed by adding one or more pins to the wheel in angularly spaced relation with the pin 66.
  • the position to which the hammer swings on its upstroke may be adjusted by changing the position of the pad 67 along the arm 57 while the distance through which the hammer falls for any given upstroke may be changed by threading the hammer into or out of the arm and then anchoring the hammer in its adjusted position with a lock nut 72 (FIG. 5).
  • By adding or removing weights 69, the force with which the hammer strikes the anvil 71 may be adjusted.
  • a shut off valve 75 is located in the outlet line 20 so that the latter can be closed off to prevent moisture from entering the cloud chamber 11 when the apparatus is not'in use.
  • an adaptor fitting 76 Fastened to the end of the outlet line 20 is an adaptor fitting 76 to which is' connected the tube 77 of a mouthpiece 79 which may' be used by the patient to facilitate inhalation of the tantalum-laden air stream.
  • the mouthpiece 79 (FIG. 6) is of unique construction and comprises a hollow. central body 80 withthree angularly spaced branches 81, 82 and 83. Telescoped detachably over the branch 81 is an inhalation tube 84 which is shaped to curve over and around the tongue without depressing the tongue so as to discharge the powder directly into the throat area and minimize the deposition of tantalum on the tongue.
  • the inhalation tube may be made of easily washable and sterilizable material or may be a disposable item.
  • a fitting 85 is telescoped into the branch 82 and is connected at one end of the tube 77 leading from the adapter 76.
  • An inlet valve 86 is located at the opposite end of the fitting and comprises an apertured rubber disc 87 which is sandwiched between the fitting and a shoulder formed within the branch 82.
  • An integral flapper 89 (FIG. 7) is hinged as indicated at 90 to one edge of the opening 91 through the disc and the flapper normally closes off the internal passage through the fitting 85.
  • the flapper 89 is sucked open at an angle to provide the most direct line of flow possible between the tube 77 and the tube 84 to reduce turbulence.
  • the flapper is forced against the fitting 85vand prevents the exhaled air from passing into the chamber 11.
  • a valve 93 (FIG. 6) similar to the valve 86 is located between the branch 83 and a telescoped fitting 94 and is positioned to close when the patient inhales and to open when the patient exhales.
  • the fitting 94 communicates with the atmosphere and is provided with a disposable filter 95 which is held on the fitting by a removable cap 96, the filter serving to clean any tantalum from the exhaled air.
  • insufflation may be effected by a catheter method.
  • a catheter tube (FIG. 8) is connected to the adaptor 76 in place of the mouthpiece tube 77 and is adapted to be inserted into the pulmonary system of the patient.
  • the tantalum-laden stream is positively forced through the outlet line 20 rather than being sucked through the line by the patient.
  • a diaphragm pump 101 (FIG. 1) is connected to the inlet line 24 by way of a line 103 and a T-fitting 104, the latter being located in the inlet line 24 between the throttle valve 45 and the desiccator 46.
  • An adjustable flow regulator valve 105 (FIG. 1) is connected into the line 103 to control the rate of flow into the chamber while a check valve 106 is located in the extreme upstream end of the inlet line 24 to prevent the pumped air from being forced out of the inlet line.
  • an electrically energizable heater 107 (FIG. 1) is placed in the inlet line 24 upstream of the T-fitting 41 and may be set to warm the air to a preselected temperature. Alternatively, the heater may be placed around the top portion 17 of the container 13.
  • a temperature sensor 110 (FIG. 1) is placed in the outlet line 20 and, if the temperature of the air flowing therethrough exceeds a predetermined safe level, the sensor acts through appropriate circuitry (not shown) to shut down the pumps 30 and 101 and the heater 107 and to trigger audio and visual alarms (not shwon). If desired, the heater also may be used with the inhalation method.
  • Apparatus for insufflating the airways of a patient with radiopaque powder comprising a container defining a chamber adapted to hold a pile of said powder, in insufflating circuit comprising an inlet line communicating with said chamber and also communicating with the atmosphere, said insufflating circuit also comprising an outlet line communicating with and leading from said chamber said outlet line being adapted to be sucked upon by the patient and constituting a means by which the patient may provide intermittant negative pressure in said chamber whereby, when the patient inhales, a stream of air is drawn into said chamber from said inlet line and flows through said chamber and into said outlet line for delivery into the airways of the patient, a cloud generating circuit comprising a pressure pump having inlet and outlet conduits, said outlet conduit being connected to the discharge side of said pump and being positioned with its discharge end located adjacent and directed toward said pile of powder whereby operation of said pump causes air to impinge against said pile and creates a cloud of powder within said chamber for entrainment in
  • Apparatus as defined in claim 1 further including a second pressure pump, means for connecting the discharge side of said second pump to said inlet line whereby operation of said second pump causes a stream of air to flow in said insufflating circuit without the patient sucking on said outlet line, means in said inlet line for preventing air in the inlet line from escaping to atmosphere during operation of said second pump, a catheter tube, and means for connecting said catheter tube to said outlet line.
  • Apparatus as defined in claim 1 further including means in said inlet line for removing moisture from said air stream before the latter enters said chamber.
  • Apparatus as defined in claim 1 further including heating means in said insufflating circuit for warming said air stream before the latter passes into said outlet line.
  • said con tainer includes a generally frusto-conical body disposed in an upright position, said pile of powder being located at the lower end of said chamber, a biological filter located in said inlet line near the upper end of said container, said inlet line terminating adjacent the upper end of said chamber, and said outlet conduit having its discharge end located adjacent the lower end of said chamber and just above said pile of powder.
  • Apparatus as defined in claim 7 further including means for vibrating said filter and said container to shake powder loose from the filter and the interior surfaces of the container.
  • Apparatus as defined in claim 10 further including a nozzle on the discharge end of said outlet conduit, said nozzle including a centrally located discharge hole extending in substantially a vertical direction and including a series of discharge holes spaced angularly around said centrally located hole and inclined downwardly and outwardly from said centrally located hole.
  • Apparatus as defined in claim 13 further including means for vibrating said container to shake powder loose from the interior surfaces of the container.
  • Apparatus as defined in claim 13 in which said means comprises a movable hammer, and mechanism for repeatedly striking said hammer against the top of said container.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • External Artificial Organs (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
US00289836A 1972-09-18 1972-09-18 Tantalum insufflator Expired - Lifetime US3777742A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28983672A 1972-09-18 1972-09-18

Publications (1)

Publication Number Publication Date
US3777742A true US3777742A (en) 1973-12-11

Family

ID=23113315

Family Applications (1)

Application Number Title Priority Date Filing Date
US00289836A Expired - Lifetime US3777742A (en) 1972-09-18 1972-09-18 Tantalum insufflator

Country Status (7)

Country Link
US (1) US3777742A (pt)
JP (1) JPS4970586A (pt)
BR (1) BR7307220D0 (pt)
CA (1) CA1001022A (pt)
DE (1) DE2344480A1 (pt)
FR (1) FR2199960B3 (pt)
GB (1) GB1430377A (pt)

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3870046A (en) * 1973-05-08 1975-03-11 Miles Lab Insufflator
US3915165A (en) * 1974-09-13 1975-10-28 Minnesota Mining & Mfg Intratracheal injection system for animals
US3980074A (en) * 1973-07-18 1976-09-14 Beecham Group Limited Device for the administration of powders
US4109656A (en) * 1977-02-07 1978-08-29 Sybron Corporation Apparatus for use with insufflators
US4120293A (en) * 1976-09-17 1978-10-17 A. Ward Ford Memorial Institute, Inc. Laser system and method
US4161944A (en) * 1976-09-17 1979-07-24 Muckerheide Myron C Laser system and method and laser amplifier for use therewith
DE3338525T (de) * 1982-03-25 1984-03-22 Carl Peter 06820 Darien Conn. Kremer jun. Verfahren und Vorrichtung für die Diagnose von Atmungserkrankungen und Allergien
US4510929A (en) * 1982-04-30 1985-04-16 Bordoni Maurice E Disposable radioactive aerosol inhalation apparatus
US4741331A (en) * 1987-02-02 1988-05-03 Atomic Products Corporation Disposable radioactive aerosol inhalation apparatus
US4782828A (en) * 1983-03-21 1988-11-08 Mallinckrodt, Inc. Radioaerosol delivery apparatus
WO1990013327A1 (en) * 1989-04-28 1990-11-15 Riker Laboratories, Inc. Dry powder inhalation device
US6116233A (en) * 1992-09-11 2000-09-12 Medic-Aid Limited Drug delivery arrangement
US20040024360A1 (en) * 2000-08-28 2004-02-05 Andy Greter Suction pump
US20070135706A1 (en) * 2005-12-13 2007-06-14 Shimko Daniel A Debridement method, device and kit
US20160016720A2 (en) * 2012-07-30 2016-01-21 P.C.O.A. Devices Ltd. Receptacle for containing and dispensing solid medicinal pills
WO2018178841A2 (en) 2017-03-31 2018-10-04 Trivikram A respiratory system
US10399725B2 (en) 2012-07-05 2019-09-03 P.C.O.A. Devices Ltd. Medication dispenser
EP3890812A1 (en) * 2018-12-04 2021-10-13 PARI Pharma GmbH Mouthpiece and nebulizer having a mouthpiece

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US277900A (en) * 1883-05-22 Heney h
US881238A (en) * 1902-12-08 1908-03-10 Sayer Hasbrouck Insufflator.
US1599959A (en) * 1923-03-23 1926-09-14 Fujimoto Buheiji Atomizer
US2535844A (en) * 1946-08-01 1950-12-26 John H Emerson Aspirator for administering medicine

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US277900A (en) * 1883-05-22 Heney h
US881238A (en) * 1902-12-08 1908-03-10 Sayer Hasbrouck Insufflator.
US1599959A (en) * 1923-03-23 1926-09-14 Fujimoto Buheiji Atomizer
US2535844A (en) * 1946-08-01 1950-12-26 John H Emerson Aspirator for administering medicine

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3870046A (en) * 1973-05-08 1975-03-11 Miles Lab Insufflator
US3980074A (en) * 1973-07-18 1976-09-14 Beecham Group Limited Device for the administration of powders
US3915165A (en) * 1974-09-13 1975-10-28 Minnesota Mining & Mfg Intratracheal injection system for animals
US4120293A (en) * 1976-09-17 1978-10-17 A. Ward Ford Memorial Institute, Inc. Laser system and method
US4161944A (en) * 1976-09-17 1979-07-24 Muckerheide Myron C Laser system and method and laser amplifier for use therewith
US4109656A (en) * 1977-02-07 1978-08-29 Sybron Corporation Apparatus for use with insufflators
DE3338525T (de) * 1982-03-25 1984-03-22 Carl Peter 06820 Darien Conn. Kremer jun. Verfahren und Vorrichtung für die Diagnose von Atmungserkrankungen und Allergien
US4510929A (en) * 1982-04-30 1985-04-16 Bordoni Maurice E Disposable radioactive aerosol inhalation apparatus
US4782828A (en) * 1983-03-21 1988-11-08 Mallinckrodt, Inc. Radioaerosol delivery apparatus
US4741331A (en) * 1987-02-02 1988-05-03 Atomic Products Corporation Disposable radioactive aerosol inhalation apparatus
US5655523A (en) * 1989-04-28 1997-08-12 Minnesota Mining And Manufacturing Company Dry powder inhalation device having deagglomeration/aerosolization structure responsive to patient inhalation
EP0705614A1 (en) * 1989-04-28 1996-04-10 Riker Laboratories, Inc. Dry powder inhalation device
WO1990013327A1 (en) * 1989-04-28 1990-11-15 Riker Laboratories, Inc. Dry powder inhalation device
US6012454A (en) * 1989-04-28 2000-01-11 Minnesota Mining And Manufacturing Company Dry powder inhalation device
US6116233A (en) * 1992-09-11 2000-09-12 Medic-Aid Limited Drug delivery arrangement
US20040024360A1 (en) * 2000-08-28 2004-02-05 Andy Greter Suction pump
US7160273B2 (en) * 2000-08-28 2007-01-09 Medela Ag Suction pump
US20070135706A1 (en) * 2005-12-13 2007-06-14 Shimko Daniel A Debridement method, device and kit
US10399725B2 (en) 2012-07-05 2019-09-03 P.C.O.A. Devices Ltd. Medication dispenser
US20160016720A2 (en) * 2012-07-30 2016-01-21 P.C.O.A. Devices Ltd. Receptacle for containing and dispensing solid medicinal pills
US10370175B2 (en) 2012-07-30 2019-08-06 P.C.O.A. Devices Ltd. Receptacle for containing and dispensing solid medicinal pills
WO2018178841A2 (en) 2017-03-31 2018-10-04 Trivikram A respiratory system
WO2018178841A3 (en) * 2017-03-31 2019-01-03 Trivikram RESPIRATORY SYSTEM
US11642479B2 (en) 2017-03-31 2023-05-09 Trivikram. Respiratory system
EP3890812A1 (en) * 2018-12-04 2021-10-13 PARI Pharma GmbH Mouthpiece and nebulizer having a mouthpiece
US20220118198A1 (en) * 2018-12-04 2022-04-21 Pari Pharma Gmbh Mouthpiece and nebulizer having a mouthpiece

Also Published As

Publication number Publication date
CA1001022A (en) 1976-12-07
DE2344480A1 (de) 1974-04-11
JPS4970586A (pt) 1974-07-08
GB1430377A (en) 1976-03-31
FR2199960A1 (pt) 1974-04-19
BR7307220D0 (pt) 1974-08-29
FR2199960B3 (pt) 1976-08-20

Similar Documents

Publication Publication Date Title
US3777742A (en) Tantalum insufflator
US4094317A (en) Nebulization system
AU2006244478B2 (en) Ultrasonic aerosol generator
US5186166A (en) Powder nebulizer apparatus and method of nebulization
US5139016A (en) Process and device for aerosol generation for pulmonary ventilation scintigraphy
US5355872A (en) Low flow rate nebulizer apparatus and method of nebulization
US6705316B2 (en) Pulmonary dosing system and method
JP3230056B2 (ja) 薬剤のエーロゾル化服用量を形成する装置
USRE30285E (en) Spraying devices, in particular nebulizing devices
US8720439B1 (en) Humidification for continuous positive airway pressure systems
US3894537A (en) Steam nebulizer
BRPI0609725B1 (pt) Dispositivo de filtro de nebulizador e sistema para aerossolização de um medicamento
US20180021530A1 (en) Aerosolization system with flow restrictor and feedback device
WO2009111612A1 (en) Aerosolization device
EP3254632A1 (en) Humidification in breathing circuits
JP2003504092A (ja) 肺投薬システムおよび方法
CN107970505B (zh) 一种便携式胰岛素雾化给药装置
EP0539674B1 (en) Aerosol generating system
CN109432556A (zh) 一种智能儿科用药物雾化器及其使用方法
US20090038610A1 (en) Inhalation device for providing a mist of nebulised liquid medical solution to a user
US6073818A (en) Apparatus for controlled delivery of powdered solid materials
AU2021101022A4 (en) Portable insulin atomization administration device
CN209451071U (zh) 一种幼儿医用雾化器
US2696210A (en) Aerosol humidifier apparatus
CN207785608U (zh) 一种气动雾化吸入器

Legal Events

Date Code Title Description
AS Assignment

Owner name: KENNER PARKER TOYS INC.

Free format text: CHANGE OF NAME;ASSIGNOR:CPG PRODUCTS CORP.;REEL/FRAME:004619/0307

Effective date: 19851121

AS Assignment

Owner name: LIEBEL-FLARSHEIM COMPANY, A CORP OF DE.

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:SYBRON CORPORATION, A CORP OF NY.;REEL/FRAME:004624/0585

Effective date: 19860731

AS Assignment

Owner name: GREAT AMERICAN INSURANCE COMPANY, A CORP OF OH,OHI

Free format text: SECURITY INTEREST;ASSIGNOR:LIEBEL-FLARSHEIM COMPANY, A DE CORP;REEL/FRAME:004648/0111

Effective date: 19861215

Owner name: GREAT AMERICAN INSURANCE COMPANY, 580 WALNUT BUILD

Free format text: SECURITY INTEREST;ASSIGNOR:LIEBEL-FLARSHEIM COMPANY, A DE CORP;REEL/FRAME:004648/0111

Effective date: 19861215