US3712475A - Positive pressure lid for dialyzer apparatus - Google Patents

Positive pressure lid for dialyzer apparatus Download PDF

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Publication number
US3712475A
US3712475A US00068294A US3712475DA US3712475A US 3712475 A US3712475 A US 3712475A US 00068294 A US00068294 A US 00068294A US 3712475D A US3712475D A US 3712475DA US 3712475 A US3712475 A US 3712475A
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United States
Prior art keywords
cover
port
chamber
blood
dialyzing fluid
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Expired - Lifetime
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US00068294A
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English (en)
Inventor
F Martinez
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Baxter International Inc
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Baxter Laboratories Inc
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/10—Spiral-wound membrane modules
    • B01D63/101—Spiral winding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24—Dialysis ; Membrane extraction
    • B01D61/28—Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24—Dialysis ; Membrane extraction
    • B01D61/32—Controlling or regulating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2313/00—Details relating to membrane modules or apparatus
    • B01D2313/18—Specific valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2313/00—Details relating to membrane modules or apparatus
    • B01D2313/21—Specific headers, end caps

Definitions

  • the present invention is within the art of artificial kidney apparatus and concerns particularly a cover member which is received on a canister or outer shell of the apparatus to enclose a dialysate chamber. More particularly, however, the cover member is sealingly received on the canister or outer shell and by provision of a valve disposed to cooperate with an outflow duct from the dialysate chamber the internal pressure may be varied.
  • dialysis is carried out in an extracorporeal system and serves to cleanse from a biological fluid, such as blood, various organic and inorganic substances which are harmful to the system;
  • a biological fluid such as blood
  • various organic and inorganic substances which are harmful to the system;
  • the biological fluid will be considered as being blood.
  • One form of dialysis apparatus includes a blood flow chamber generally in the form of an elongated length of plastic tubing which may be wrapped upon a core and a dialysate chamber within which the blood chamber is disposed and through which a dialyzing fluid or wash solution is flowed.
  • a blood flow chamber generally in the form of an elongated length of plastic tubing which may be wrapped upon a core and a dialysate chamber within which the blood chamber is disposed and through which a dialyzing fluid or wash solution is flowed.
  • a semipermeable dialyzing membrane for example Cuprophanwhich is a cellulose base membrane similartov cellophane
  • the flow of blood and dialyzing fluid over each increment of membrane and on opposite sides of the membrane is preferably kept steady and continuous, even at the membrane surface where the requirement of flow is most important. In this connection the presentationof a stationary liquid film at the membrane surface would reduce solute diffusion efficiency.
  • Ultrafiltration also occurs during solute diffusion. Ultrafiltration is a phenomena which is not totally un' derstood. Further, a complete discussion of what is thought to be the scientific principle and reasons for the occurrence of water diffusion from blood plasma is outside the scope of this invention; However, it is thought that ultraflltration is a consequence or a function of many dialyzer characteristics. Thus, ultraflltration is determined by,'among other considerations, the transmembrane pressure gradient, area of dialyzer and perfusion flow rate, water permeability of the membrane and boundary layer conditions. Of these, probably the most important consideration is the transmembrane pressure gradient.
  • p is the viscosity of the test solution in dynessec/cm
  • Land W are the length and width of the dialyzer blood path in cm
  • H is the blood passage thickness in cm.
  • Q is the test solution flow rate in cm second.
  • AP in ost
  • the mean pressure across the blood compartment would be the average pressure between inlet and outlet of the dialyzer blood compartment
  • TP P,,,+P,,, /2
  • the mean pressure across the dialysate compartment would be the average pressure between the inlet and outlet dialyzer dialysate compartment.
  • the transmembrane pressure gradient may be reduced by pressurizing the dialysate chamber thereby to decrease the volume of water diffused from the plasma within the blood chamber into the dialysate compartment. This has been accomplished without detriment to the solute removal efficiency of the dialyzer.
  • a cover adapted for receipt upon the outer shell or canister defining the dialysate chamber of a coil-type dialyzer.
  • the cover is provided with means to secure the same in a sealed manner on the outer shell or canister thereby to permit the build-up of a positive pressure within the dialysate chamber.
  • the cover is formed with a passage through which dialyzing fluid passes from the chamber to be recirculated, as choice determines, and a valve mechanism operable in conjunction with the passage to change the resistance to flow thereby to develop or release pressure in the dialysate chamber. A pressure increase will simultaneously diminish the transmembrane pressure gradient.
  • the cover may be formed as an integral unit while in a slightly modified form of the present invention the cover may include a plate member of substantially flat construction and an annular ring member cooperable with the plate and serving as a mount for the latter on the outer shell or canister.
  • the plate as the cover described above, includes in conjunction with the dialysate outflow passage valving structure.
  • the ring is provided with a plurality of cutouts for the introduction of one or more flexible tubes forming a part of the blood circulatory system and for connecting the blood chamber therein.
  • a guide block is formed within the cover to both receive and accommodate as well as to grip a plurality of flexible tubes connecting the blood compartment into the blood circulating system.
  • the guide block is formed by a member capable of pivotal movement into and out of as well as up and down within a cutout portion of the cover and along the longitudinal axis of the cover when receiving the plurality of tubes.
  • the block includes a plurality of semicircular cutouts formed to cooperate with complementary cutouts within a shoulder to positively grip the several tubes in position.
  • a port in communication with the chamber and a nipple mount adapted to connect a form of pressure measuring gauge.
  • FIG. 1 is a view in elevation, partly broken away and in section, of a coil dialyzer and the dialyzer cover;
  • FIG. 2 is a side elevation of the dialyzer cover and partially showing exploded therefrom a canister or dialyzer shell to which the cover is sealingly mounted;
  • FIG. 3 is a top plan view of the dialyzer cover
  • FIG. 4 is a bottom plan view of the dialyzer cover
  • FIG. 5 is a vertical sectional view as seen along the line 5-5 of FIG. 3 showing the flow port through the dialyzer cover and a valve member in the port;
  • FIG. 6 is a view in perspective of a portion of the dialyzer cover and a gate portion for supporting one or more fluid lines;
  • FIG. 7 is a partial vertical section through the dialyzer cover illustrating the manner of mounting on the canister or dialyzer shell;
  • FIGS. 8 and 9 are partial vertical sections through the dialyzer cover gate illustrating in sequence the manner in which the fluid lines are positioned and supported;
  • FIG. 10 is a horizontal section as seen along the lines 10-10 in FIG. 5 illustrating the port valve and that through rotation the volume of flow through the port may be changed;
  • FIG. 11 is an exploded perspective of a modified fonn of the dialyzer cover and showing a lip portion of a canister or shell;
  • FIG. 12 is a breakaway view in elevation illustrating the positioning of the cover on the canister or shell;
  • FIG. 13 is a bottom plan view of the dialyzer cover less annular ring as seen in FIG. 1 1;
  • FIG. 14 is a vertical section as seen along the line 14-14 in FIG. 13 and including in section a portion of the annular ring and canister or shell;
  • FIG. 15 is a view similar to that of FIG. 12 illustrating the manner of receiving the cover, by clamping members, on the canister or shell.
  • a coil dialyzer of the type adapted to utilize the dialyzer cover of the present invention may be seen in FIG. 1. While the dialyzer construction and operation per se are not important to an understanding of this invention it is considered important to develop a background so that the present invention may be more clearly understood.
  • an extracorporeal device such as is shown in FIG. 1, there is. passive physical diffusion of unwanted organic and inorganic substances across a semipermeable membrane as a consequence of driving force (chemical concentration gradient) from two moving fluids on opposed sides of the semipermeable membrane.
  • driving force chemical concentration gradient
  • the membrane which may be in the form of an extended length of tube necessarily needs support throughout this length. This is particularly true in the coil-type dialyzer as is shown in -FIG. 1. Therefore, as generally illustrated, an extended length of supported membrane tub,- ing is wrapped upon a core 12 within the area bounded by a canister or shell 14.
  • sup port structure is not shown in any detail since its construction is outside the scope of this invention. However, it is to be kept in mind that it serves to both sup-' port the membrane and allow a maximum of exposed membrane surface to the flow of dialyzing fluid.
  • the membrane is connected to an a bottom wall 20 of the dialyzer assembly.
  • the dialyzing fluid may be uniformly introduced into the assembly thereby to flow uniformly over the total membrane surface toward the dialyzing fluid outflow port.
  • the reservoir container may be supported by surface 28. Any particular system for this purposemay be utilized. Such systems are well-known in the art. However, since dialysis efficiency gradually diminishes with the action of the apparatus, because of the diffusion gradient progressively falling off, through operation, it is appropriate to both drain off a small portion of the dialyzing fluid and to replenish it with an equivalent amount of fresh dialyzing fluid thereby to maintain the diffusion gradient.
  • the reservoir may be provided with an overflow determining the height of the reservoir or a tap or spout 30 within the wall of container 26.
  • dialyzercover generally identified, by the numeral 50, which will now be described.
  • the dialyzing cover is illustrated as having a substantially flat upper surface 52 and generally of circular construction throughout. Depending from the peripheral region of the cover is an annular ring 54 providing a mounting surface for the cover on the canister or shell 14 whichis formed with an upper outturned lip 56.
  • the cover 50 may be formed of any material which may be fabricated as by molding and thereafter capable of being machined.
  • the material of the cover should also provide a sturdy construction thereby to be a rigid assembly for a dialyzer unit.
  • the construction also will be of the type capable of maintaining desired pressure conditions within an enclosed space.
  • any of the commonly used metals, such as aluminum, or any of the widely used plastics, such as polypropylene, high density polyethylene, Lucite, among others, may be employed. If the cover is desirably to be transparent or translucent one of the plastic materials may be preferred.
  • the cover 50 is mounted so that a bottom portion of the annular ring 54 rests upon the upper surface of lip 56.
  • a further extending annular ring 58 is received within the upper opening of the shell 14 to position properly the cover.
  • An O-ring 60 carried by the annular portion 54 serves to provide an airtight seal for the shell interior or dialysate chamber in which the dialyzing membrane is disposed.
  • a plurality clamping assemblies including a post 62 having a central longitudinal bore 64, an elongated threaded bolt 66 which extends throughout the bore and which terminates in a foot portion 68, as well as a knurled thumb screw are integral with or otherwise carried by the cover at spaced locations therearound.
  • the cover 50 Preferably there may be three or four assemblies for the purpose of securely and sealingly mounting the cover 50.
  • the several feet 68 are received under the shell lip 56 thereby tightening the knurled screw 70 to compress the O-ring 60 between the annular ring and lip 56.
  • a plurality of projections 72 are carried by or integral with the underside of the cover (FIG. 4). The projections serve to provide with the perforated annular ring 24 supporting confinement for the wrapped membrane 10 within the dialysate chamber.
  • the body of the cover 50 provides within a peripheral sector a somewhat trapezoidal shaped cutout 74.'The amount of cutout within an upper portion is greater than that within the lower portion thereby to provide a shoulder 75.
  • a guide block 76 is mounted for swinging movement into and out of the opening 74 as well as longitudinal movement within the opening between the FIG. 8 and 9 positions. The need to accommodate and provide for this movement will become apparent as the description continues.
  • the guide block is dimensioned to be complementary with the shoulder and provide a smooth peripheral outer surface of the cover as in FIG. 6.
  • a pair of hinges 78 and 80 are carried by the guide block and cover body, respectively.
  • the hinges intercooperate by the provision of pin being received within the turned extremity 84 of binge 78.
  • a lock plate 85 and cooperating knurled screw 86 are carried at the opposite side of the guide block to secure the latter in the closed position.
  • Both the shoulder 75 and the inside surface of the guide block carry a plurality of cooperating semicircular cutouts 88 and 90 forming a series of circular openings 92. These openings accommodate the tubes 94 which serve to connect the diffusion membrane into an extracorporeal circulatory blood path. The provision of a set or sets of two openings 92 permit a single or dual wrapped diffusion membrane to be connected into the system.
  • the guide block is movable between FIG. 8 and FIG. 9 positions. This movement permits the several tubes 94 to be partially supported by the semicircular cutouts 88 and 90 (FIG. 8) whereupon the guide block is lowered (FIG. 9) so that the tubes are gripped within the openings 92.
  • the tubes could not be otherwise gripped solely by pivotal closure of the guide block. Thus, if the tubes were to be received within the cutouts 88 they, upon closure of the guide block, would be pinched.
  • a port or channel 96 is formed within the cover body. This port or channel provides for discharge of dialyzing fluid from the dialysate chamber into the reservoir 26.
  • a spout or splash shield 98 is mounted at the end of the port to direct the flowing dialyzing fluid into the reservoir 26.
  • the channel includes a horizontal passage 100 and a communicating vertical passage 102.
  • a rotary valve 104 is disposed within the vertical passage and upon rotation may provide either an increase or decrease in the volume of outflow of dialyzing fluid.
  • the valve includes a generally cylindrical lower shaft portion 106 having an opening 108 in one wall portion of a size substantially equal to the cross-sectional size of the horizontal passage.
  • the upper shaft 110 terminates in a hand gripping member to enable the operator to rotate the valve shaft with relative ease thereby to adjust the flow of dialyzing fluid.
  • a U- shaped clamp plate 112 intercooperates with an annular cutout 114 in the valve shaft to allow rotation of the valve within the port 96 yet at the same time to prevent the valve from being withdrawn from the passage 102.
  • the cover is mounted as described and blood is caused to pass through the membrane or blood chamber.
  • Simultaneously dialyzing fluid is introduced into the dialysate chamber and because of a maintained diffusion gradient across the membrane the diffusion of unwanted organic and inorganic substances continues.
  • the pressure within the blood chamber is in excess of the pressure within the dialysate chamber thereby creating a pressure gradient across the membrane with consequent ultrafiltration or diffusion of water to the area of lower pressure.
  • a positive pressure may be developed within the dialysate chamber thereby to decrease the transmembrane pressure gradient and decrease the amount of water diffusion from the plasma.
  • the dialysate chamber pressure may be read on a pressure meter 116 mounted by a connector 118 communicating with the interior of the dialysate chamber thereby to maintain the chamber at the desired pressure.
  • the cover 200 is formed of a plate section 202 and an annular ring section 204.
  • the ring section 204 is substantially similar in construction to the depending ring section 54 of cover 50.
  • the plate section 202 is substantially similar to the corresponding portion of cover 50.
  • the dialyzing fluid outflow port is defined by a plurality of passages 208 214 in communication with the dialysate chamber. By the provision of passages of varying size the volume of flow through the port and the chamber pressure may be controlled with some 'degree of precision.
  • a cover or shield 206 provides an enclosure over the outflow port and serves to direct with limited splashing the dialyzing fluid into the fluid reservoir.
  • a control member 216 is supported for rotation by the shield 206 and the bottom surface of plate section 202.
  • the control is defined by a shaft 218 which carries a knob 220 at one end and a curved, flat plate 222 at the other.
  • the ring 204 and plate 202 are adapted to be mounted upon the canister or shell 14 of the coil dialyzer 10.
  • the annular ring 204 includes an O-ring 230 which rests upon the lip 56 while a second O-ring 232 provides a seal at the junction between the annular ring and the plate 202.
  • a projection 234 on the annular ring serves to position the cover 200 upon the shell 14.
  • a plurality of clamping members 236 are supported in spaced relation on the plate 202. As shown, the clamps are mounted by supporting lu'gs 238 which are frictionally or otherwise received within openings 240 formed in the plate 202 at approximately spaced locations.
  • the several clamps are identical in construction and therefore only one such clamp is illustrated.
  • the clamp comprises a bifurcated body 242 having a base 242 into which the lug 238 is joumelled for rotation.
  • the clamp through appropriate mounting is also capable of pivotal movement about the lug.
  • An arm 244 having a finger gripping end 246 is mounted on the body and capable of being pivoted about the body. Through manipulation of the body and arm the finger gripping end 246 may be received under the lip 56. Movement of body 242 from a raised pivotal position to the position of FIG. 15 serves to securely grip the lip thereby to positively mount the cover 200.
  • a nipple 248 supported by the plate 202 in communication with a passage 250 connecting the dialysate chamber is adapted to receive a pressure gauge, such as gauge 1 16, for the same purpose.
  • the ring 204 in the present modification provides a plurality of channels 252 to accommodate the tubes.
  • the O-ring 232 cooperates with the channel surfaces to grip the tubes without pinching.
  • a cover for dialyzer apparatus having a dialysate chamber through which dialyzing fluid is circulated continuously thereby to be in contact over a surface within said chamber of a blood compartment adapted to confine a blood stream and formed by a membrane providing a semipermeable interface between said dia lyzing fluid and blood through which because of a concentration gradient unwanted organic and inorganic substances diffuse from the blood into said dialyzing fluid, said cover comprising a body portion, said body portion including a dish-shaped member and a annular member, means on said body portion adapting said cover for receipt on said apparatus thereby to isolate said chamber from ambient conditions, means including a plurality of substantially radially disposed grooves in an upper surface of said annular member juxtaposed to said dish-shaped member when said members are received together for permitting unrestricted access of at least an inlet and an outlet tube into said chamber thereby to connect said blood compartment in an extracorporeal fluid system, means carried by one of said members to provide a seal therebetween, port means including a plurality of passages'formed
  • the cover of claim 3 comprising a post, said post extending through said shield and said body and mounted for rotary movement, and said adjustable means comprising a plate carried by one end of said post and movable with said post thereby to adjust said volume of flow.
  • said cooperable means includes a flat plate mounted for rotation substantially in a plate including entrance to said port means thereby through movement to adjust the effective opening of the same, and means supported by said cover for moving said plate.
  • the cover of claim 1 including means carried by one of said apparatus and body to provide a fluid seal between said body and apparatus when received.
  • the cover of claim 1 including means on said body adapted to mount a gauge to monitor chamber pressure.
  • a cover for dialyzer apparatus having a dialysate chamber through which dialyzing fluid is circulated continuously thereby to be in contact over a surface within said chamber of a blood compartment adapted to confine a blood stream and formed by a membrane roviding a semipermeable interface between said diayzing fluid and blood through which because of a concentration gradient unwanted organic and inorganic substances diffuse from the blood into said dialyzing fluid, said cover comprising a body portion, said body portion being provided with a peripheral cutout of substantially trapezoidal shape and having a lower shoulder means for permitting access of at least an inlet and an outlet tube into said chamber thereby to connect said blood compartment in an extracorporeal fluid system, said means including a guide block, said guide block.
  • one of said plurality of passages is defined by a longitudinal substantially cylindrical opening through said body and a second of said plurality of passages being defined by a transverse communicating bore.
  • said adjustable means comprises a substantially cylindrical cup-shaped element received for rotation within said opening, said cup-shaped element having an opening within one wall of a size substantially equal to the size of said transverse bore, and means in said cover for rotating said element to vary the effective port opening.
  • the cover of claim 11 including means to maintain the vertical longitudinal disposition of said cupshaped element yet permit rotation of said element within said opening.
  • the cover of claim 9 comprising hinge means allowing movement of said guide block between a normal lowered position within said peripheral cutout to a raised position at which through pivotal movement out of said peripheral cutout said tubes may be received by I said guide block grooves whereupon said guide block is redisposed in the normal position at which said tubes are positioned within said circular openings.
  • the cover of claim 9 comprising a shield over the end of said port means to prevent splashing of said dialyzing fluid exiting said port means.
  • the cover of claim 9 including means carried by one of said apparatus and body to provide a fluid seal between said body and apparatus when received on the latter.
  • the cover of claim 9 including means on said body adapted to mount a gauge to monitor chamber pressure.

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  • Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Water Supply & Treatment (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
US00068294A 1970-08-31 1970-08-31 Positive pressure lid for dialyzer apparatus Expired - Lifetime US3712475A (en)

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US6829470A 1970-08-31 1970-08-31

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US (1) US3712475A (fr)
AU (1) AU3120071A (fr)
BE (1) BE770106A (fr)
CA (1) CA988435A (fr)
DE (1) DE2141602A1 (fr)
FR (1) FR2106193A5 (fr)
GB (1) GB1355385A (fr)
ZA (1) ZA714494B (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3815743A (en) * 1971-06-09 1974-06-11 D Snyder Method and apparatus for hemodialysis
US3962095A (en) * 1973-06-22 1976-06-08 Sandoz Ltd. Dialyser cartridge
US4024059A (en) * 1974-04-23 1977-05-17 Rhone-Poulenc Industries Artificial kidney
US4231875A (en) * 1977-05-13 1980-11-04 Gambro Ab Diffusion apparatus utilizing tubular semi-permeable membrane
US20090008306A1 (en) * 2007-07-05 2009-01-08 Baxter International Inc. Extracorporeal dialysis ready peritoneal dialysis machine
EP2942070A3 (fr) * 2014-05-08 2016-01-13 B. Braun Avitum AG Conduite en tuyaux flexibles pour liquides de dialyse usagés ou frais
US9440017B2 (en) 2013-03-14 2016-09-13 Baxter International Inc. System and method for performing alternative and sequential blood and peritoneal dialysis modalities
CN108888816A (zh) * 2015-11-29 2018-11-27 杭州跟策科技有限公司 血液透析容器

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL50623A (en) * 1975-10-08 1981-07-31 Baxter Travenol Lab Dialyzer construction
ATE10583T1 (de) * 1980-08-22 1984-12-15 The Stolle Research And Development Corporation Haemoperfusionsvorrichtung fuer die spezifische aenderung oder entfernung von komponenten aus dem blut.
CN112403278B (zh) * 2017-01-05 2022-05-17 佛山市顺德区美的饮水机制造有限公司 端盖、螺旋卷式反渗透膜元件及净水器

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1235625A (en) * 1917-02-24 1917-08-07 Lillian H Wineman Cover for cooking utensils.
US1657173A (en) * 1927-02-16 1928-01-24 Morrison Bros Strainer and check valve

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1235625A (en) * 1917-02-24 1917-08-07 Lillian H Wineman Cover for cooking utensils.
US1657173A (en) * 1927-02-16 1928-01-24 Morrison Bros Strainer and check valve

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3815743A (en) * 1971-06-09 1974-06-11 D Snyder Method and apparatus for hemodialysis
US3962095A (en) * 1973-06-22 1976-06-08 Sandoz Ltd. Dialyser cartridge
US4024059A (en) * 1974-04-23 1977-05-17 Rhone-Poulenc Industries Artificial kidney
US4231875A (en) * 1977-05-13 1980-11-04 Gambro Ab Diffusion apparatus utilizing tubular semi-permeable membrane
US20090008306A1 (en) * 2007-07-05 2009-01-08 Baxter International Inc. Extracorporeal dialysis ready peritoneal dialysis machine
US8512553B2 (en) 2007-07-05 2013-08-20 Baxter International Inc. Extracorporeal dialysis ready peritoneal dialysis machine
US9440017B2 (en) 2013-03-14 2016-09-13 Baxter International Inc. System and method for performing alternative and sequential blood and peritoneal dialysis modalities
US10632243B2 (en) 2013-03-14 2020-04-28 Baxter International Inc. System and method for performing alternative and sequential blood and peritoneal dialysis modalities
EP2942070A3 (fr) * 2014-05-08 2016-01-13 B. Braun Avitum AG Conduite en tuyaux flexibles pour liquides de dialyse usagés ou frais
CN108888816A (zh) * 2015-11-29 2018-11-27 杭州跟策科技有限公司 血液透析容器
CN108888816B (zh) * 2015-11-29 2020-12-01 鄂东医疗集团市中心医院(市普爱医院湖北理工学院附属医院) 血液透析容器

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Publication number Publication date
GB1355385A (en) 1974-06-05
CA988435A (en) 1976-05-04
FR2106193A5 (fr) 1972-04-28
AU3120071A (en) 1973-01-18
ZA714494B (en) 1972-03-29
DE2141602A1 (de) 1972-03-09
BE770106A (fr) 1971-12-01

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