US3658059A - Inhaler - Google Patents

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Publication number
US3658059A
US3658059A US883058A US3658059DA US3658059A US 3658059 A US3658059 A US 3658059A US 883058 A US883058 A US 883058A US 3658059D A US3658059D A US 3658059DA US 3658059 A US3658059 A US 3658059A
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US
United States
Prior art keywords
inhaler
opening
nozzle
baffle
accordance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US883058A
Inventor
Emeram Steil
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RITZAU PAUL PARI BETEILIGUNGS- und VERWALTUNGSGELLSCHAFT & Co HOLDING mbH
RITZAU PAUL PARI-WERK GmbH
Original Assignee
RITZAU PARI WERK KG PAUL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE1813993A priority Critical patent/DE1813993C3/de
Application filed by RITZAU PARI WERK KG PAUL filed Critical RITZAU PARI WERK KG PAUL
Application granted granted Critical
Publication of US3658059A publication Critical patent/US3658059A/en
Assigned to RITZAU PAUL PARI BETEILIGUNGS- UND VERWALTUNGSGELLSCHAFT MIT BESCHRAENKTER HAFTUNG & CO. HOLDING reassignment RITZAU PAUL PARI BETEILIGUNGS- UND VERWALTUNGSGELLSCHAFT MIT BESCHRAENKTER HAFTUNG & CO. HOLDING CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). EFFECTIVE JULY 15,1981 Assignors: RITZUA PAUL PARI-WERK KG.
Assigned to RITZAU PAUL PARI-WERK GMBH reassignment RITZAU PAUL PARI-WERK GMBH ASSIGNMENT OF ASSIGNORS INTEREST. Assignors: PAUL RITZAU PARI BETEILIGUNGS-UND VERWALTUNGSESELLSCHAFT MIT BESCHANKTER HAFTUNG & CO. HOLDING
Anticipated expiration legal-status Critical
Application status is Expired - Lifetime legal-status Critical

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/06Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001Particle size control
    • A61M11/002Particle size control by flow deviation causing inertial separation of transported particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/002Details of inhalators; Constructional features thereof with air flow regulating means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/06Respiratory or anaesthetic masks

Abstract

An inhaler is provided with a baffle for changing the effective size of the passage for passing the suspension to be inhaled in such a manner that the centre of the effective aperture left by the baffle moves towards the jet of the inhaler when the aperture is increased in size and moves away from it when the aperture is reduced in size.

Description

[451 Apr. 25, 1972 References Cited UNITED STATES PATENTS United States Patent Steil [54] INHALER [72] Inventor:

Emeram Steil, Starnberg, Germany PATENTEDAPR 25 |912 SHEET 1 ur 2 PATENTEDAPRESS?? 3,658,059

SHEET 2 or 2 Fig.2

INHALER The present invention relates to inhalers for producing suspensions of liquid or pulverulent materials, and more particularly though not exclusively to such inhalers as comprise a suspension outlet opening which is comparatively large in size in comparison with the jet of the inhaler, and means for adjust- One object of the invention is to provide an inhaler of the type described above in which a simple manipulation is sufficient to adjust the quantity of suspension and also the size of the suspended particles during operation as may be required. A further object of the invention is to provide an inhaler which provides a finer suspension when the quantity of suspension is reduced.

The present invention consists in an inhaler for administring a suspension of particles, comprising a nozzle for entraining the particles, and a duct for guiding the particle suspension to a patient for inhalation, the duct defining a suspension outlet opening with a cross-section which is considerably larger than the internal cross-section of the nozzle, and a baffle which is arranged to cooperate with the duct in varying the size of the outlet opening, the centre of the effective opening being moved towards the jet when the opening is increased in size and moved away from it when the baffle is moved to reduce the size ofthe opening.

Generally the suspension particles become finer with the increase in the distance from the nozzle, since the coarser particle settle more readily. Consequently as the bale is moved so as to bring about an increasing closing of the opening only the fine particle leave the inhaler and, with a suitable construction of the apparatus, fall back into means forv storing the liquid or powder to be inhaled.

Preferably the baffle is arranged to rotate and can be constructedas a cylindrical baffle which is coaxially arranged in a suitable tube forming part of the duct, through which the suspension leaving the nozzle region passes upwards. In this case an aperture for the suspension is left in the tube and this aperture can be closed to a greater or lesser extent by the baffle. If the tube is arranged vertically the deposit ofthe coarser particles occurs to a greater degree so that there is a guarantee that as the opening is closed to a greater and greater extent only fine suspension particles will leave the inhaler. In order to ensure that there is a linear relationship between movement of the baffle and change in the size of the vopening the closing edge ofthe baffle can be made helical.

Further details of the invention will be gathered from thefollowing description of a preferred embodiment of it referring to the accompanying drawings.

FIG. 1 is a longitudinal section through the inhaler.

FIG. 2 is a front view of the upper part of the inhaler in which the suspension outlet opening can be seen with the baffle in the open position` i FIG. 3 is a similar view with the baffle closed.

FIG. 4 is a view of the baffle removed from the rest of the inhaler.

FIG. 5 is a plan view of the baffle looking in the direction of its axes of rotation.

The inhaler shown in FIG. 1 comprises a base 1, which together with a screwed-on intermediate part 2 forms a handle for holding the inhaler. In the intermediate part 2, in which the medium 3 to be suspended is contained, the atomising or suspending nozzle 4 is mounted, which is provided with a central air channel 5 and suction channels 6 on both sides of it for l the medium to be suspended.

The air channel 5 i's connected with an air duct v7 of larger cross-section which passes transversely through the base l and is connected with a nipple 8 for a compressed air hose. A discharge opening 9 at the other end can be closed as desired by a rubber button 10 on an actuating lever l1 so that the compressed air supplied to the inhaler is only forced to pass through the nozzle 4 when the lever 11 is operated. In this manner it is possible to use the inhaler only during actual breathing in. l

Directly above the nozzle there is a gas flow deflector l2 which in a conventional manner aids in atomisation.

On the intermediate part 2 a substantially cylindrical tube 13 is screwed which forms a continuation of the intermediate part. This tube has-a suspension outlet opening 14 in its side (see FIG. 2), whichhas a cross-section which is large in comparison with the internal cross-section of the nozzle. The opening adjoins a breathing mask 15. y

The tube 13 is closed at its free upper end except for a coaxial hole which is defined by an inwardly projecting lip or neck 16. A tubular inlet sleeve 17 is mounted in the lip 16 so that it can rotate and serves for the supply of additional air into the inhaler. l

The baffle 19 is mounted on the sleeve 17 by means of a connecting piece 18 (FIG. 5). The baffle 19 surrounds the axis of the `sleeve 17 concentrically and in developed view has approximately the shape of a right-angle triangle or trapezium. Accordingly the closing edge 20 of the baffle 19 has a helical shape.

The feature that the closing edge is on the side of the baffle 19 removed from the nozzle 4 is especially important to ensure that the suspension outlet opening 14 is closed in such a manner that its centre moves upwards during the process of closing of the opening. This ensures that on reducing the size of the suspension outlet opening at the end of the movement only the finest particles can leave the device while the coarser particles are deposited adjacent to the nozzle or owing to the reduced gas speed fall back into the liquid or powder with which the inhaler has been charged.

With the inhaler described it is possible by a simple manipulation not only to adjust the rate of supply of the suspension but also tol regulate the particles size as may be desired, a

, knurled ring 21 being provided at the outerv end of the suction sleeve 17. On rotating the sleeve 17 the baffle 19 is also lrotated so that the suspension outlet opening is closed to a greater and greater extent as can be seen from FIGS. 2 and 3.

It is naturally possible to make modifications in the embodiment ofthe invention specifically described. More particularly the device in accordance with the invention can be used for purposes other than inhalation purposes.

The embodiments of the invention in which an exclusive property or privilege is claimed are as follows:

l'. An inhaler for vaporizing and atomizing liquid or pulverulent materials, comprising:

' a. a chamber for liquid or pulverulent material,

b. a source of` gas under pressure, c. nozzle means communicating with the chamber and the source for entraining the liquid or pulverulent material with the gas, v d. passage means communicating with the nozzle on one `end and defining an outlet opening on the other end for directing an entrained mixture to an inhalor, and

e. adjustable baffle means rotatably mounted adjacent the opening and having an inclined, helical closing edge remote from the nozzle and extendable across the opening, whereby the closing edge moves away from the nozzle when the opening is reduced.

2. An inhaler in accordance with claim l in which the baffle means is coaxially mounted with respect to the passage means and wherein the closing edge cooperates with the openingto define the effective cross-sectional area thereof.

3. An inhaler in accordance with claim 1 in which the passage means is substantially vertical in normal operation.

4. An inhaler in accordance with claim 2 further comprising a sleeve member on which the baffle is mounted for introducing air into the inhaler.

* 1k Ik k

Claims (4)

1. An inhaler for vaporizing and atomizing liquid or pulverulent materials, comprising: a. a chamber for liquid or pulverulent material, b. a source of gas under pressure, c. nozzle means communicating with the chamber and the source for entraining the liquid or pulverulent material with the gas, d. passage means communicating with the nozzle on one end and defining an outlet opening on the other end for directing an entrained mixture to an inhalor, and e. adjustable baffle means rotatably mounted adjacent the opening and having an inclined, helical closing edge remote from the nozzle and extendable across the opening, whereby the closing edge moves away from the nozzle when the opening is reduced.
2. An inhaler in accordance with claim 1 in which the baffle means is coaxially mounted with respect to the passage means and wherein the closing edge cooperates with the opening to define the effective cross-sectional area thereof.
3. An inhaler in accordance with claim 1 in which the passage means is substantially vertical in normal operation.
4. An inhaler in accordance with claim 2 further comprising a sleeve member on which the baffle is mounted for introducing air into the inhaler.
US883058A 1968-12-11 1969-12-08 Inhaler Expired - Lifetime US3658059A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE1813993A DE1813993C3 (en) 1968-12-11 1968-12-11

Publications (1)

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US3658059A true US3658059A (en) 1972-04-25

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Family Applications (1)

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US883058A Expired - Lifetime US3658059A (en) 1968-12-11 1969-12-08 Inhaler

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US (1) US3658059A (en)
AT (1) AT306224B (en)
CH (1) CH513656A (en)
DE (1) DE1813993C3 (en)
GB (1) GB1283988A (en)

Cited By (74)

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US4454877A (en) * 1981-05-26 1984-06-19 Andrew Boettner Portable nebulizer or mist producing device
US4524769A (en) * 1981-07-08 1985-06-25 Aktiebolaget Draco Dosage inhalator
US4534345A (en) * 1981-07-08 1985-08-13 Aktiebolaget Draco Dosage inhalator
US4566451A (en) * 1982-07-02 1986-01-28 Plantorgan Werk Heinrich G. E. Christensen Kg Vapor inhalation device
US4657007A (en) * 1982-06-28 1987-04-14 Whittaker General Medical Corporation Nebulizer
US4792097A (en) * 1987-03-31 1988-12-20 Mallinckrodt, Inc. Non-sputtering nebulizer
US5062419A (en) * 1991-01-07 1991-11-05 Rider Donald L Nebulizer with valved "T" assembly
WO1992004066A1 (en) * 1990-09-12 1992-03-19 Hans Bisgaard An inhaling device
US5161524A (en) * 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
US5170782A (en) * 1991-09-12 1992-12-15 Devilbiss Health Care, Inc. Medicament nebulizer with improved aerosol chamber
US5186166A (en) * 1992-03-04 1993-02-16 Riggs John H Powder nebulizer apparatus and method of nebulization
US5209225A (en) * 1991-11-19 1993-05-11 Glenn Joseph G Flow through nebulizer
US5235969A (en) * 1990-08-20 1993-08-17 Intersurgical (Guernsey) Limited Nebulizer having combined structure for removing particles over two microns
US5355872A (en) * 1992-03-04 1994-10-18 Riggs John H Low flow rate nebulizer apparatus and method of nebulization
US5392768A (en) * 1991-03-05 1995-02-28 Aradigm Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval
US5394866A (en) * 1991-03-05 1995-03-07 Aradigm Corporation Automatic aerosol medication delivery system and methods
US5404871A (en) * 1991-03-05 1995-04-11 Aradigm Delivery of aerosol medications for inspiration
US5450336A (en) * 1991-03-05 1995-09-12 Aradigm Corporation Method for correcting the drift offset of a transducer
US5497764A (en) * 1991-03-05 1996-03-12 Aradigm Corporation Medication cassette for an automatic aerosol medication delivery
US5497763A (en) * 1993-05-21 1996-03-12 Aradigm Corporation Disposable package for intrapulmonary delivery of aerosolized formulations
US5509404A (en) * 1994-07-11 1996-04-23 Aradigm Corporation Intrapulmonary drug delivery within therapeutically relevant inspiratory flow/volume values
US5549102A (en) * 1991-11-07 1996-08-27 Paul Ritzau Pari-Werk Gmbh Nebulizer, especially for application in devices for inhalation therapy
US5584285A (en) * 1995-06-07 1996-12-17 Salter Labs Breathing circuit apparatus for a nebulizer
US5709202A (en) * 1993-05-21 1998-01-20 Aradigm Corporation Intrapulmonary delivery of aerosolized formulations
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US5829435A (en) * 1997-02-24 1998-11-03 Aradigm Corporation Prefilter for prevention of clogging of a nozzle in the generation of an aerosol and prevention of administration of undesirable particles
US5954047A (en) * 1997-10-17 1999-09-21 Systemic Pulmonary Development, Ltd. Methods and apparatus for delivering aerosolized medication
US5983893A (en) * 1994-12-21 1999-11-16 Astra Aktiebolag Inhalation device
US6044841A (en) * 1997-08-29 2000-04-04 1263152 Ontario Inc. Breath actuated nebulizer with valve assembly having a relief piston
US6062214A (en) * 1996-10-30 2000-05-16 Bespak Plc Inhaler for medicament
US6085741A (en) * 1995-06-06 2000-07-11 Pari Gmbh Spezialisten Fur Effektive Inhalation Device for atomisation of fluids
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US6491233B2 (en) 2000-12-22 2002-12-10 Chrysalis Technologies Incorporated Vapor driven aerosol generator and method of use thereof
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US6551542B1 (en) 1998-11-16 2003-04-22 Aradigm Corporation Method of fabricating porous membrane with unique pore structure for aerosolized delivery of drugs
US6557552B1 (en) 1998-10-14 2003-05-06 Chrysalis Technologies Incorporated Aerosol generator and methods of making and using an aerosol generator
US20030089367A1 (en) * 2001-11-12 2003-05-15 Riccardo Abate Device for washing nasal cavities and collecting catarrhal matter
US6568390B2 (en) 2001-09-21 2003-05-27 Chrysalis Technologies Incorporated Dual capillary fluid vaporizing device
US20030108342A1 (en) * 2001-12-06 2003-06-12 Sherwood Timothy S. Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate
US6612303B1 (en) 1996-02-13 2003-09-02 1263152 Ontario Inc. Nebulizer apparatus and method
US6640050B2 (en) 2001-09-21 2003-10-28 Chrysalis Technologies Incorporated Fluid vaporizing device having controlled temperature profile heater/capillary tube
US6681769B2 (en) 2001-12-06 2004-01-27 Crysalis Technologies Incorporated Aerosol generator having a multiple path heater arrangement and method of use thereof
US6681998B2 (en) 2000-12-22 2004-01-27 Chrysalis Technologies Incorporated Aerosol generator having inductive heater and method of use thereof
US20040016427A1 (en) * 2000-04-27 2004-01-29 Byron Peter R. Method and apparatus for generating an aerosol
US20040031485A1 (en) * 2002-08-19 2004-02-19 Andre Rustad Small volume nebulizer
US6701922B2 (en) 2001-12-20 2004-03-09 Chrysalis Technologies Incorporated Mouthpiece entrainment airflow control for aerosol generators
US6701921B2 (en) 2000-12-22 2004-03-09 Chrysalis Technologies Incorporated Aerosol generator having heater in multilayered composite and method of use thereof
US20040241800A1 (en) * 1999-05-20 2004-12-02 Jue Rodney Alan Vascular endothelial growth factor dimers
US20040255941A1 (en) * 2000-12-22 2004-12-23 Chrysalis Technologies Incorporated Disposable aerosol generator system and methods for administering the aerosol
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US20050158394A1 (en) * 2000-02-28 2005-07-21 Vectura Limited Delivery of oral drugs
US6994083B2 (en) 2001-12-21 2006-02-07 Trudell Medical International Nebulizer apparatus and method
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Cited By (151)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4454877A (en) * 1981-05-26 1984-06-19 Andrew Boettner Portable nebulizer or mist producing device
US4524769A (en) * 1981-07-08 1985-06-25 Aktiebolaget Draco Dosage inhalator
US4534345A (en) * 1981-07-08 1985-08-13 Aktiebolaget Draco Dosage inhalator
US4657007A (en) * 1982-06-28 1987-04-14 Whittaker General Medical Corporation Nebulizer
US4566451A (en) * 1982-07-02 1986-01-28 Plantorgan Werk Heinrich G. E. Christensen Kg Vapor inhalation device
US4792097A (en) * 1987-03-31 1988-12-20 Mallinckrodt, Inc. Non-sputtering nebulizer
US5235969A (en) * 1990-08-20 1993-08-17 Intersurgical (Guernsey) Limited Nebulizer having combined structure for removing particles over two microns
WO1992004066A1 (en) * 1990-09-12 1992-03-19 Hans Bisgaard An inhaling device
US5755221A (en) * 1990-09-12 1998-05-26 Bisgaard; Hans Aerosol inhaler with piston dump
US5062419A (en) * 1991-01-07 1991-11-05 Rider Donald L Nebulizer with valved "T" assembly
US5542410A (en) * 1991-03-05 1996-08-06 Aradigm Corporation Delivery of aeerosol medications for inspiration
US5655516A (en) * 1991-03-05 1997-08-12 Aradigm Corporation Delivery of aerosol medications for inspiration
US5497764A (en) * 1991-03-05 1996-03-12 Aradigm Corporation Medication cassette for an automatic aerosol medication delivery
US5622162A (en) * 1991-03-05 1997-04-22 Aradigm Corporation Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval
US5392768A (en) * 1991-03-05 1995-02-28 Aradigm Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval
US5394866A (en) * 1991-03-05 1995-03-07 Aradigm Corporation Automatic aerosol medication delivery system and methods
US5404871A (en) * 1991-03-05 1995-04-11 Aradigm Delivery of aerosol medications for inspiration
US5450336A (en) * 1991-03-05 1995-09-12 Aradigm Corporation Method for correcting the drift offset of a transducer
US5743252A (en) * 1991-03-05 1998-04-28 Aradigm Corporation Method for releasing controlled amount of aerosol medication
US5608647A (en) * 1991-03-05 1997-03-04 Aradigm Corporation Method for releasing controlled amount of aerosol medication
US5755218A (en) * 1991-03-05 1998-05-26 Aradigm Corporation Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval
US5520166A (en) * 1991-03-05 1996-05-28 Aradigm Corporation Medication cassette for an automatic aerosol medication delivery system
US5826570A (en) * 1991-03-05 1998-10-27 Aradigm Corporation Delivery of aerosol medications for inspiration
US5161524A (en) * 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
US5170782A (en) * 1991-09-12 1992-12-15 Devilbiss Health Care, Inc. Medicament nebulizer with improved aerosol chamber
US5549102A (en) * 1991-11-07 1996-08-27 Paul Ritzau Pari-Werk Gmbh Nebulizer, especially for application in devices for inhalation therapy
US5209225A (en) * 1991-11-19 1993-05-11 Glenn Joseph G Flow through nebulizer
US5186166A (en) * 1992-03-04 1993-02-16 Riggs John H Powder nebulizer apparatus and method of nebulization
US5355872A (en) * 1992-03-04 1994-10-18 Riggs John H Low flow rate nebulizer apparatus and method of nebulization
US5544646A (en) * 1993-05-21 1996-08-13 Aradigm Corporation Systems for the intrapulmonary delivery of aerosolized aqueous formulations
US5718222A (en) * 1993-05-21 1998-02-17 Aradigm Corporation Disposable package for use in aerosolized delivery of drugs
US6123068A (en) * 1993-05-21 2000-09-26 Aradigm Corporation Systems for the intrapulmonary delivery of aerosolized aqueous formulations
US5709202A (en) * 1993-05-21 1998-01-20 Aradigm Corporation Intrapulmonary delivery of aerosolized formulations
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GB1283988A (en) 1972-08-02
CH513656A (en) 1971-10-15
AT306224B (en) 1973-03-26
DE1813993A1 (en) 1970-06-18
DE1813993C3 (en) 1974-01-24

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