US3583399A - Self-aspirating syringe - Google Patents

Self-aspirating syringe Download PDF

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Publication number
US3583399A
US3583399A US854054A US3583399DA US3583399A US 3583399 A US3583399 A US 3583399A US 854054 A US854054 A US 854054A US 3583399D A US3583399D A US 3583399DA US 3583399 A US3583399 A US 3583399A
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United States
Prior art keywords
membrane
plunger
ampul
tubular body
syringe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US854054A
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English (en)
Inventor
Anthony F Ritsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca Canada Inc
Astra Pharmaceuticals Ltd
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Astra Pharma Inc
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403—Ampoule inserted into the ampoule holder
    • A61M2005/2414—Ampoule inserted into the ampoule holder from the side
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2433—Ampoule fixed to ampoule holder
    • A61M2005/2437—Ampoule fixed to ampoule holder by clamping means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
    • A61M5/2466—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase
    • A61M2005/247—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase with fixed or steady piercing means, e.g. piercing under movement of ampoule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2477—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means to reduce play of ampoule within ampoule holder, e.g. springs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3112—Incorporating self-aspirating means, e.g. to provide flashback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3148—Means for causing or aiding aspiration or plunger retraction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S604/00—Surgery
    • Y10S604/90—Telltale showing entry of blood into body inserted conduit

Definitions

  • ABSTRACT A hypodermic syringe for medical, dental, or (51] Int. Cl A6lm 5/24, veterinary use employing cartridge ampuls f injectable fl id 1 1/06 arranged to be automatically self-aspirating.
  • a resilient mem- [501 Field of Search 128/218 R, brane is d fl t d at the f d end f the ampul rearwardly Z 21 218 D, P, 221, 272 of the ampul each time the syringe plunger is actuated, so that upon release of the plunger the membrane is automatically [56] References cued resiliently restored to its normal position thereby producing UNITED STATES PATENTS conditions of reduced pressure or aspiration within the ampul. 1,712,070 5/1929 Cressler 128/218D The membrane is deflected on a stud positioned at the forward 1,798,117 3/1931 Brockway....
  • This invention relates to improvements in hypodermic syringes and in particular to a new or improved self-aspirating syringe.
  • Aspiration is the procedure whereby an operator in making an injection determines whether or not the needle is in a proper position for injecting to prevent inadvertent deposition of injection solution directly into a blood vessel which could cause untoward patient reaction.
  • the syringe is manipu' lated to create a reduced pressure within the fluid to be injeeted whereby if the needle is uncorrectly positioned, blood from the area to be injected is drawn back through the hypodermic needle into the syringe where it can be observed by the operator.
  • cartridge am puls of injectable fluid are now commonly used in hypodermic syr inges.
  • Such ampuls usually comprise a cylindrical container of glass or clear plastics material, the forward end of which is sealed by a rubber membrane and the rear end of which is sealed by a rubber piston which is slidable within the body of the container.
  • cartridge ampuls are positioned within the barrel of a syringe so that the membrane is pierced by the rear end of the needle and the rubber piston is ad vanced by a thumb-operated plunger to inject the fluid.
  • a selfaspirating syringe adapted for use with a plunger-type cartridge ampul of the type comprising a tubular body filled with injectable fluid closed at one end by a movable piston member and at the other end by a flexible membrane, said syringe comprising: a body member having a cavity adapted to accommodate therewithin one of said cartridge ampuls, and having axially disposed openings at the front and rear ends thereof; a plunger member extending through the opening at the rear end of said cavity and slidable with respect thereto, said plunger having a head at its forward end adapted to engage the said movable piston member to slide the same forwardly within said tubular body, and a thumb piece or palm rest at the rear end thereof for pressing said plunger forward; a adapter within the opening at the front end of the syringe body member arranged to receive and secure hypodermic needle in axial alignment with said tubular body with the rear end of
  • the plunger is guided within a bushing in the opening in the rear end of the body member, the bushing itself being movable axially of the opening and being resilient urged in a forwards direction to engage the rear end of the cartridge ampul.
  • the rear end of the bushing carries a flange to the rear of the syringe body whereby the bushing can be manually engaged and moved axially to cause aspiration of the syringe without movement of the plunger.
  • the stud means may comprise a central rearwardly projecting stud integral with the adapter or alternatively may comprise a collar on the hypodermic needle itself arranged to seat against the rear face of the adapter when the needle is secured therein.
  • the invention provides a plunger-type cartridge ampul comprising a generally tubular container having a rear end sealed by a piston which is movable axially of the container, and a front end sealed by a resilient membrane associated with which is a central forwardly projecting element which is capable of transmitting to the membrane a deflection inwards of the front end of the container.
  • the forwardly projecting element associated with the membrane performs the same function as the stud means referred to above in the aspiration of the syringe.
  • FIG. I is a perspective view of a plunger-type cartridge am- P
  • FIG. 2 is a longitudinal sectional view of a self-aspirating hypodermic syringe according to the invention
  • FIG. 3 and 4 are fragmentary sectional views to a larger scale illustrating details of the operation of the syringe of FIG.
  • FIG. 5 is a fragmentary sectional view showing a modified syringe
  • FIG. 6 is a fragmentary longitudinal sectional view of a modified cartridge ampul according to the invention.
  • FIG. 1 illustrates a cartridge ampul 10 of known kind which comprises a container defined by generally cylindrical glass wall sealed at one end by a rubber piston 11 and at the other end by a rubber membrane 12.
  • the injectable fluid is sealed in the container between the piston 11 and membrane 12.
  • the membrane is secured against the end of the container by an annular sheet metal collar 13, one end of which is spun or crimped into a depression 14 in the surface of the container and the other end of which carries an inwardly projecting radial flange 15 which overlies the peripheral area of the membrane and presses it against the end of the container.
  • the syringe generally indicated at 16 in FIG. 2 comprises a cylindrical barrel [7 defining a cavity 18 to receive a cartridge ampul 10.
  • the barrel 17 is formed with a large axially extending aperture (not shown) in its wall to permit insertion and removal of the ampul.
  • the forward end of the barrel is secured to a fitting I9 formed with a central axially directed screw-threaded opening 20.
  • An adapter 21 in threaded engagement with the opening 20 is formed with a central stud 22 which projects rearwardly into the cavity 18.
  • the front end of the adapter 21 is formed with a spigot 23 which is in threaded engagement with a hub 24 which carries an axially extending hypodermic needle 25.
  • the needle 25 extends rearwardly from the hub through an axial bore 26 in the adapter and in the stud 22 and extends into the cavity 18 beyond the stud 22.
  • the rear end of the barrel I7 is received in a fitting 27 which carries a pair of laterally extending finger grips 28.
  • a sleeve 29 in threaded engagement with the fitting 27 carries at its rear end a gland 30 having a radial flange 31.
  • the gland 30 extends forwardly within the sleeve 29 and its inner surface forms a smooth cylindrical continuation of the inner surface of the barrel 17.
  • a bushing 32, which extends through an axial hole in the gland 30, has a flanged head 33 which is guided for reciprocating movement by the cylindrical inner surface of the gland.
  • the rear end of the bushing 32 carries a radially extending flange 34 secured thereto by a retaining clip 35.
  • the bushing is surrounded within the gland 30 by a compression spring 36 acting between the flanged head 33 and the end wall of the gland 30 and urging the bushing in a forward direction.
  • the bushing is preferably of a low friction material such as nylon and is formed with a central bore within which is slidably received a plunger 37.
  • the forward end of the plunger carries a head 38 adapted to engage the rubber piston of an ampul 10.
  • the plunger 37 may be pressed forward by means of a thumb plate 39 carried on the rear end thereof. In the retracted position of the plunger 37, the head 38 is received in a recess 40 in the forward end of the flanged head of the bushing 32.
  • the plunger 37 is withdrawn rearwardly and the ampul is inserted through the aperture in the barrel 17, plunger end firstv
  • the plunger is thereafter released and the bushing 32 is advanced under the force of the compression spring 36 until the flanged head thereof engages the end of the cylindrical wall of the ampul.
  • This movement forces the ampul 10 forward so that the membrane 12 of the ampul is pierced by the rear end of the hypodermic needle 25.
  • the end of the stud 22 at the forward end of the cavity 18 rests against the membrane 12 but the strength of the spring 36 is chosen such that this engagement does not cause any appreciable deflection of the membrane.
  • Aspiration can also be effected by pressing forward and releasing the flange 34 of the bushing 32 as indicated by the arrows in FIG. 2.
  • the piston II is adapted to engage the internal wall of the ampul 10 with sufficient friction to enable the head 38 to cause the membrane 12 to be flexed as shown in FIGS. 3 and 4, and also to permit the ejection of the contents of the ampul when and as desired.
  • an adapter 210 also constitutes a hub to secure a hypodermic needle 25a in the forward end of the syringe.
  • the stud means is formed not on the adapter but as a collar 41 on the needle 25a itself.
  • the collar 41 is positioned to the rear of the adapter 210 and performs a function similar to that of the stud 22 in the embodiment of FIGS. 2 to 4.
  • an ampul b generally similar to the one illustrated in FIG. 1, has an aspirating element 42 positioned between the collar 13! and the membrane 121;.
  • the element 42 comprises an outwardly extending radial flange 43 positioned between the radial flange b of the collar 13b and the membrane 12b and a forwardly extending tubular portion 44 extending from the front end of the ampul.
  • the ampul 10b when fitted in a syringe 16 of the type shown in FIG. 2, the adapter of which does not have the stud 22, will perform the same aspirating function as the stud 22 or as the collar 41 in the em bodiment shown in FIG. 5.
  • a self-aspirating syringe for use with a plunger-type cartridge ampul of the type comprising a tubular body filled with injectable filled fluid having a rear end closed by a movable piston member and a forward end closed by a flexible resilient membrane, said syringe comprising: a body member having means providing a cavity to accommodate therewithin one of said cartridge ampules, and having axially disposed openings at the front and rear ends thereof; a plunger member extending through the opening at the rear end of said cavity and slidable with respect thereto, said plunger having a head at its forward end adapted to engage the said movable piston member to slide the same forwardly within said tubular body, and a manually engageable actuator at the rear end thereof for pressing said plunger forward; means for mounting an adapter within the opening at the front end of the syringe body member, said adapter being arranged to receive and secure a hypodermic needle in axial alignment with said tubular body with the rear end of the needle extending
  • a self-aspirating syringe according to claim 1 wherein said plunger member is guided to slide within a bushing carried within said opening at the rear end of the body member, said bushing having a front end adapted to extend within the rear end of the tubular body of the cartridge ampul, said bushing extending rearwardly through said opening at the rear end of said body member and being axially slidable therein, and wherein resilient means engaging said bushing are adapted controllably to bias said bushing in a forward direction.
  • a self-aspirating syringe according to claim 2 wherein said bushing carries a flange at the rear of the syringe body member by means of which the bushing can be engaged and moved axially to urge said cartridge ampul forward; whereby said membrane is stretched inwardly of said tubular body and upon release of said bushing the tubular body moves rearwards under the influence of said stretched membrane to create conditions for aspiration within said tubular body.
  • a plunger-type cartridge ampul for use in a hypodermic syringe comprising a generally tubular container having a rear end sealed by a piston which is movable axially of the container, and a front end sealed by a resilient membrane, the cartridge having a central forwardly projecting element at the forward end thereof which in use is operative to transmit to the membrane a deflection rearwardly of the front end of the container.
  • a plunger-type cartridge ampul according to claim 8 wherein said membrane is secured to the front end of the container by an annular collar which has a radial inwardly-projecting flange which overlies the peripheral area of said membrane, said element comprising a short tubular member extending forwardly from the membrane and having a radial outwardly extending flange retained between the membrane and the collar flange.
  • a self-aspirating syringe comprising a generally tubular body having a cavity and an open rear end and a plunger-type cartridge ampul received in said syringe body and comprising a tubular body filled with injectable fluid and having a rear end closed by a movable piston member and a forward end closed by a flexible resilient membrane, the syringe having an axially disposed plunger extending through the opening in the rear end thereof and into the cavity and being axially movable said plunger having a forward end having a head operative to and engaging said membrane, said abutment means being operative, upon forward movement of said ampul in said cavity under the influence of said plunger, to stretch said membrane rearwardly of said tubular body, whereby upon release of said influence said stretched membrane is operative to move said tubular body rearwardly to create conditions of aspiration within said ampul.

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
US854054A 1968-09-03 1969-08-29 Self-aspirating syringe Expired - Lifetime US3583399A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA29115 1968-09-03
US85405469A 1969-08-29 1969-08-29

Publications (1)

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US3583399A true US3583399A (en) 1971-06-08

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US854054A Expired - Lifetime US3583399A (en) 1968-09-03 1969-08-29 Self-aspirating syringe

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US (1) US3583399A (xx)
BE (1) BE738268A (xx)
BR (1) BR6912040D0 (xx)
CA (1) CA873458A (xx)
FR (1) FR2017285A1 (xx)
GB (1) GB1252306A (xx)
NL (1) NL6913362A (xx)
SE (1) SE367765B (xx)

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US3797487A (en) * 1970-10-29 1974-03-19 Woelm Fa M Hypodermic syringe with clutch for aspiration
US3809298A (en) * 1973-07-18 1974-05-07 Precision Sampling Corp Syringe
US3878846A (en) * 1971-12-13 1975-04-22 Spad Lab Hypodermic syringe with parts disposable after use
US3977402A (en) * 1975-03-25 1976-08-31 William Floyd Pike Injection apparatus and method with automatic aspiration feature
US3990446A (en) * 1975-02-18 1976-11-09 Jewel Dean Randolph Taylor Hypodermic syringe for stabilized aspiration by one hand
US4216771A (en) * 1976-12-14 1980-08-12 Sven Arlers Hypodermic syringe with aspiration effect
US4333456A (en) * 1981-02-09 1982-06-08 Sterling Drug Inc. Self-aspirating hypodermic syringe and self-aspirating assembly therefor
US4333457A (en) * 1981-02-09 1982-06-08 Sterling Drug Inc. Self-aspirating syringe with frictionally engaged locking collet
US4381779A (en) * 1981-07-16 1983-05-03 Sterling Drug Inc. Deformable slidable piston to provide self-aspiration in hypodermic cartridge ampoules
US4407283A (en) * 1981-10-19 1983-10-04 Dale C. Grier Self-injecting syringe
EP0109913A3 (fr) * 1982-11-03 1984-09-12 Micro-Mega Seringue dentaire pour injections intra-ligamentaires
US4540405A (en) * 1983-07-12 1985-09-10 Cilco, Inc. Disposable syringe sleeve
EP0160711A1 (de) * 1984-05-03 1985-11-13 Bünder Glas GmbH Injektionsspritze
US4744791A (en) * 1986-12-18 1988-05-17 Georges Egolf Syringe with automatic piston retraction
US4883472A (en) * 1985-11-08 1989-11-28 Disetronic Ag. Injection device
US5232457A (en) * 1991-08-05 1993-08-03 Grim John P Medical syringe
US5505704A (en) * 1993-04-02 1996-04-09 Eli Lilly And Company Manifold medication injection apparatus and method
US5536249A (en) * 1994-03-09 1996-07-16 Visionary Medical Products, Inc. Pen-type injector with a microprocessor and blood characteristic monitor
US5584815A (en) * 1993-04-02 1996-12-17 Eli Lilly And Company Multi-cartridge medication injection device
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US6500239B2 (en) 2001-03-14 2002-12-31 Penjet Corporation System and method for removing dissolved gas from a solution
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US8728046B2 (en) 2010-08-10 2014-05-20 Spiracur Inc. Controlled negative pressure apparatus and alarm mechanism
US8753322B2 (en) 2010-08-10 2014-06-17 Spiracur Inc. Controlled negative pressure apparatus and alarm mechanism
US9067023B2 (en) 2011-11-21 2015-06-30 University Of Louisville Research Foundation, Inc. Ergonomic syringe and adaptor
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US10493204B2 (en) 2016-11-11 2019-12-03 Imam Abdulrahman Bin Faisal University Aspirator syringe with blood detector
US10923222B2 (en) 2017-03-15 2021-02-16 Novartis Ag System for administering a pharmaceutical product
US11103420B2 (en) 2017-03-15 2021-08-31 Novartis Ag Medical device, programming device, wireless terminal, and medical system
US11355225B2 (en) 2017-03-15 2022-06-07 Novartis Ag System for use of a pharmaceutical product
US11607486B2 (en) 2017-03-16 2023-03-21 Novartis Ag Injector device
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US4370987A (en) * 1980-10-07 1983-02-01 Seymour Bazell Medical fluid collection device
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US4886495A (en) * 1987-07-08 1989-12-12 Duoject Medical Systems Inc. Vial-based prefilled syringe system for one or two component medicaments
GB2210268A (en) * 1987-02-25 1989-06-07 Duoject Inc Syringe system
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Also Published As

Publication number Publication date
SE367765B (xx) 1974-06-10
BR6912040D0 (pt) 1973-02-13
CA873458A (en) 1971-06-15
NL6913362A (xx) 1970-03-05
FR2017285A1 (xx) 1970-05-22
GB1252306A (xx) 1971-11-03
BE738268A (xx) 1970-02-16

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