US3437050A - Peristaltic pumping device - Google Patents

Peristaltic pumping device Download PDF

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Publication number
US3437050A
US3437050A US608171A US3437050DA US3437050A US 3437050 A US3437050 A US 3437050A US 608171 A US608171 A US 608171A US 3437050D A US3437050D A US 3437050DA US 3437050 A US3437050 A US 3437050A
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United States
Prior art keywords
hose
pressure
elastic
peristaltic
roller
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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US608171A
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English (en)
Inventor
Jiri Hrdina
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Czech Academy of Sciences CAS
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Czech Academy of Sciences CAS
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    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B7/00—Piston machines or pumps characterised by having positively-driven valving
    • F04B7/0042—Piston machines or pumps characterised by having positively-driven valving with specific kinematics of the distribution member
    • F04B7/0053—Piston machines or pumps characterised by having positively-driven valving with specific kinematics of the distribution member for reciprocating distribution members
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/12—Machines, pumps, or pumping installations having flexible working members having peristaltic action
    • F04B43/1223—Machines, pumps, or pumping installations having flexible working members having peristaltic action the actuating elements, e.g. rollers, moving in a straight line during squeezing
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B7/00—Piston machines or pumps characterised by having positively-driven valving

Definitions

  • the present invention relates to an improved method of pumping liquids through elastic, more particularly small-diameter tubes or hoses, and an apparatus for carrying out this method.
  • a common feature of many processes generally used in various laboratory techniques is the necessity of transporting liquids from a vessel to another through one or more elastic, more particularly small-diameter tubes or hoses.
  • One of the problems connected with the said procedure is to secure the proportionality of fiow rate in individual tubings.
  • Two principal types of so called peristaltic pumps are well-known and conventionally used for the punpose.
  • the first of the peristaltic pump types as hereinbefore set forth comprises two or more pressure rollers caused to revolve along a circular path, which rollers press one or more elastic hoses spaced in juxtaposition on to an internal, or external cylindrical surface of a support member the elastic hose bears upon and to which it is secured.
  • the pressure rollers are mounted on a carrier member adapted to rotate about an axis which is identical with that of the thrust zone of said cylindrical supporting surface.
  • the second type of peristaltic pumps is analogous to the lastmentioned with the exception that it comprises plurality of pressure rollers rolling in a similar manner along one or more elastic hoses spaced in juxtaposition on a flat surface, the rolling movement of the pressure "atent O 3,437,950 Patented Apr. 8, 1969 rollers accomplishing a peristaltic effect upon the elastic hoses, which movement is derived from a suitable driving means by the intermediary of for example two endless Galls chains led over two pairs of sprocket wheels, respectively, one pair thereof being positively driven.
  • An essential drawback of the apparatus hereinbefore set forth consist in that it is very difficult to achieve a precise control of hydraulic pressure in the elastic hoses. Substantially it is possible to mo'dilficate the transflux through the hose by jump only, that means by replacing a hose for another one having a different diameter but approximately the same wall thickness. In this way it is possible to achieve an appropriate deformation of the hose up to the complete choke without being necessary to adjust the distance between the pressure roller exerting a peristaltic pressure upon the elastic hose, and the cflat surface of said stationary support.
  • a rolling speed control of the peristaltic pressure rollers is not recommendable since it is, with the difficulties to be met with the construction of such an apparatus in view, rather problematic, lets not say impossible, particularly with such apparatuses possessing an advantage that consists in that by a single pressure element more than one elastic hose are peristaltically deformed.
  • an apparatus comprising one or more elastic hoses adapted to be deformed on their cross section with the aim to interrupt the flow of the liquid therein by the peristaltic pressure roller, or the squeeze element, which apparatus is characterized in that the elastic hoses are squezzed alternately by thrust of the single peristaltic pressure roller rolling therealong within a predetermined path defined by two disengagement positions, on the one hand, and of the squeeze element, on the other hand.
  • the operating length of the path of the peristaltic pressure roller as well as the thrust of the same and/or the squeeze element upon the elastic hose can be adjusted by suitable means.
  • one set of cams and levers to cause movements of the operating parts as well as one peristaltic pressure roller and/ or one squeeze element can operate a plurality of elastic hoses.
  • FIG. 1 is a schematic showing indicating the principle of operation of my new device
  • FIG. 2 is a front view partly in section of an embodiment of my new device
  • FIG. 3 shows an amended detail in a front view partly in section
  • FIGS. 4, 5 and 6 show in front view partly in section H other amendments.
  • the hose or other elastic tubular member 1 made of silicone rubber or any other suitable elastic material is pressed against the flat surface 3 of a prop body 4 by a roller 2 which can move along the hose 1 exerting a peristaltic pressure thereupon.
  • the roller 2 is rotatable on shaft 6 which is mounted on the free end of a draw rod 5, its other end thereof being linked at 7 to one arm of the crank lever 8 which oscillates on the stationary pivot 9.
  • the other arm of crank lever 8 holds at its end the follower roller 10 which cooperates with the cam 11 being permanently forced against its surface by the spring 13.
  • the cam 11 and other cams hereinafter to be mentioned, such as cam 25, are fixed to a common shaft 12 which is driven by a not shown electric motor.
  • the shaft 6 carrying the press roller 2, or a number of such rollers each cooperating with one of a plurality of hoses, also additionally supports one or more guide rollers 14 moving on the flat surface 15 of a thrust plate 16 which is supported by swing arms 19, linked thereon by the pivots 17, 18 and turnable on the stationary pivots 21, 22.
  • Arm 19 forms a crank with arm 23 which carries at its free end a follower roller 24 held by not shown means in permanent engagement with cam 25 on shaft 12.
  • Still another not shown third cam on shaft 12 engages permanently the follower roller 27 mounted at the free end of arm 26 which is swinga'bly mounted on the stationary pivot 28 and rigidly associated with the hooked arm 29 whose nose 30 is adapted to squeeze the elastic hose 1 as shown.
  • the cams cooperating with the follower rollers 10, 24, 27 are properly shaped and associated to insure the required chronological action of roller 2, of thrust plate 16 and of the squeezing nose 30.
  • FIG. 2 The before described apparatus shown in FIG. 2 will operate as follows in accordance with the schematic showing in FIG. 1 to which reference is made hereinafter:
  • FIG. 2 illustrates the device at the start of the operational cycle.
  • the elastic hose 1 which receives fluid in the direction of arrow 70 is squeezed by the nose 30 of arm 29 and the pressure roller 2 is raised by thrust plate 16 and its follower roller 14 in the direction of arrow E in FIG. 1 from a disengaged position into a position strongly compressing the hose 1 and closing its cross sectional area.
  • the not shown cam acting upon follower roller 27 causes the nose 30 to release its squeeze as indicated by arrow H in FIG. 1 and cam 11 causes the pressure roller 2 to move to the left along the hose 1 as indicated by arrow F in FIG. 1.
  • the prop block 4 may be tiltably mounted in stationary bearings 33, 34 by means of pivots 31, 32.
  • One pivot 32 and possibly also the other pivot 31 may support a holder 35 provided with a guide channel 36 for the hose 1 which is positionally secured by the latch 37 adjustably attached by screw 38 to holder 35.
  • the prop member 4 may preferably be made of a translucent material to permit observation of the hose 1 during the peristaltic operation.
  • FIG. 3 shows a section in a plane passing through the axis of shaft 6 in an embodiment permitting concurrent operation on several hoses 1, 1, 1", particularly of different diameter. To this effect the surface 3 of the prop member 6 is staggered as shown.
  • the guide roller 14 cooperating with the thrust plate 15 is designed as a roller bearing and so can be the pressure roller 2 and the link 39 of draw rod 5 and shaft 6.
  • FIG. 4 shows in a front view partly in section a detail of the device illustrated in FIG. 2 modified to permit adjusting the length (L in FIG. 1) of the peristaltic motion of the pressure roller 2 along hose 1.
  • the draw rod 5, or each of a plurality thereof, is linked at 7 to an arm 40 swingably mounted on the stationary pivot 9 which also supports the swing plate member 41 with roller 10 forced against and engaging cam 11 by the action of spring 52 leaning against the stationary prop 51.
  • the arm 40 is loaded by a spring 43 leaning against prop member 44 on swing plate 41 and is pressed in clockwise direction to lean against the stop member 42 on plate 41 so that the lateral movement of the draw rod 5 with pressure roller 2 conforms to the movement of the plate 41 as if they would be rigidly connected.
  • the swing movement of arm 40 will be arrested in a predeterminable position while plate 40 will continue the swing around pivot 9 compressing spring 52 against the stationary stop 51.
  • the adjusting screw 47 penetrates the nut 48 which is preferably slit and can be tightened by the bolt 49.
  • the nut 48 or possibly a plurality of them is mounted on a stationary bar 50. It will be understood that the adjusting screw 47 will control the lateral move of the pressure roller 2 and thus its peristaltic action upon the elastic hose 1 between a maximum and zero.
  • FIG. 5 shows another modification of the embodiment illustrated in FIG. 2 to permit the nose 30 to exert an adjustable squeezing force upon the elastic hose 1.
  • the nose 30 on arm 29 does not act directly on the hose but through another intermediate lever 53 oscillatable on stationary pivot 54 and provided with the squeezing nose '55.
  • the nose 30 acts against a leaf spring 56 secured to lever 53 by screw 57, said leaf spring being supported and biased by an abutment member 58 with screw 59 which can be positionally adjusted as indicated by arrow 61 within the elongated slot 60 in arm 53.
  • FIG. 6 shows still another modification of the embodiment illustrated in FIG. 2 permitting adjustment of the pressure of roller 2 upon hose 1.
  • the draw rod 5 bearing the pressure roller 2 in linked by pivot 62 to a swing lever 63 carrying the guide roller 14 actuated by the surface 15 of thrust plate 16.
  • the pressure of roller 2 upon hose 1 results from spring 64 which is attached to arm 63 by screw '65 and is adjustable by the grub screw 66 in lug 67 of draw rod 5.
  • the distance between rollers 2 and 4 determines the bias range of spring 64 and can be adjusted by screw 68 in lug 69 of rod 5.
  • An apparatus for peristallic pumping liquid through at least one elastic tubular member comprising in combination (a) at least one elastic tubular member having at least partially a straight portion, and a prop member therefor;
  • first cam means and a first leverage associated with the pressure member to press the same against the tubular member while being moved towards the squeezing member and to distance the same from the tubular member while returning;
  • a pumping device compris-i ing a draw rod within the first leverage
  • the third cam means with its third leverage being timely coordinating with the first and second cam means and their leverages to alternately press and release the pressure member on its forward and return movement.
  • a pumping device comprising first cam means and first leverage means including a spring loaded crank lever having two arms;
  • the second leverage having two rigidly associated arms, a follower at the end of one crank arm and at the end of the other crank arm a nose forming the squeezing member.
  • a pumping device comprising a draw rod attached with one end to the pressure member and with its other end to a swing lever oscillating about a stationary pivot;
  • first spring means ensuring cooperation of said follower with said first cam means
  • a stop member on the plate member t arrest the turning movement of the SWlIlg lever and second spring means on the plate member initiating such turning; and adjustable stop means for the other end of the 1 draw bar to limit the turning of the swing lever.
  • a pumping device comprising a lever having a nose at its end interposed between the other crank arm and the tubular member and an adjustable spring on said lever cooperating with the nose of the other crank arm.
  • a pumping device comprising a draw rod attached with one end to the pressure member and with its other end to the first leverage;

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Reciprocating Pumps (AREA)
US608171A 1966-01-10 1967-01-09 Peristaltic pumping device Expired - Lifetime US3437050A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS14366 1966-01-10

Publications (1)

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US3437050A true US3437050A (en) 1969-04-08

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US608171A Expired - Lifetime US3437050A (en) 1966-01-10 1967-01-09 Peristaltic pumping device

Country Status (6)

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US (1) US3437050A (de)
AT (1) AT272843B (de)
BE (1) BE692331A (de)
DE (1) DE1653397A1 (de)
GB (1) GB1162961A (de)
SE (1) SE328192B (de)

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3489097A (en) * 1968-05-08 1970-01-13 William Gemeinhardt Flexible tube pump
US3726613A (en) * 1970-10-12 1973-04-10 Casimir W Von Pulsefree peristaltic pump
US3756752A (en) * 1971-12-20 1973-09-04 G Stenner Peristaltic pump
US3913636A (en) * 1973-04-10 1975-10-21 Ei Mochida Apparatus for automatically distributing a determined amount of liquid
US3935885A (en) * 1974-02-01 1976-02-03 Alter Richard R Capsule-filling machines
US4165954A (en) * 1975-08-11 1979-08-28 Corning Glass Works Linear peristaltic pump having pivotal pump arm
US4492531A (en) * 1982-04-30 1985-01-08 Kuraray Co., Ltd. Apparatus for producing a controlled pulsed liquid flow
US4976593A (en) * 1986-12-03 1990-12-11 Meddiss, Incorporated Pulsatile flow delivery apparatus
US5131823A (en) * 1990-03-28 1992-07-21 Orthoconcept S.A. Device for joining a connection piece to peristaltic pump
US5427274A (en) * 1992-07-23 1995-06-27 Wood; Robert Product delivery system for delivering sterile liquid product
US5431307A (en) * 1994-08-26 1995-07-11 Gencorp Inc. Dispensing plural components
US5640756A (en) * 1995-02-08 1997-06-24 Gencorp Inc. Manufacturing system
CN107246380A (zh) * 2017-07-21 2017-10-13 长沙执先智量科技股份有限公司 一种直线式蠕动泵
CN107246379A (zh) * 2017-07-21 2017-10-13 长沙执先智量科技股份有限公司 一种直线式高精度蠕动泵
CN107269502A (zh) * 2017-05-18 2017-10-20 长沙执先智量科技股份有限公司 一种直线式高精度蠕动泵
CN109098956A (zh) * 2018-09-30 2018-12-28 长沙执先智量科技股份有限公司 一种直线式洁净蠕动计量泵
WO2021086990A1 (en) * 2019-10-29 2021-05-06 Quantum-Si Incorporated Peristaltic pumping of fluids for bioanalytical applications and associated methods, systems, and devices
WO2021086985A1 (en) * 2019-10-29 2021-05-06 Quantum-Si Incorporated Peristaltic pumping of fluids and associated methods, systems, and devices
CN113117183A (zh) * 2021-04-21 2021-07-16 苏州市立医院 一种可调管径的蠕动泵配药机
WO2021188580A1 (en) * 2020-03-17 2021-09-23 Detect, Inc. Rapid diagnostic test

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US473546A (en) * 1892-04-26 Surgical pump
US2412397A (en) * 1943-12-31 1946-12-10 Lyndus E Harper Flexible tube pump
US3083647A (en) * 1961-05-08 1963-04-02 John T Muller Metering device
US3292667A (en) * 1963-12-12 1966-12-20 Bittner Precision fluid metering device
US3359910A (en) * 1965-06-10 1967-12-26 Little Inc A Apparatus for programming fluid flow

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US473546A (en) * 1892-04-26 Surgical pump
US2412397A (en) * 1943-12-31 1946-12-10 Lyndus E Harper Flexible tube pump
US3083647A (en) * 1961-05-08 1963-04-02 John T Muller Metering device
US3292667A (en) * 1963-12-12 1966-12-20 Bittner Precision fluid metering device
US3359910A (en) * 1965-06-10 1967-12-26 Little Inc A Apparatus for programming fluid flow

Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3489097A (en) * 1968-05-08 1970-01-13 William Gemeinhardt Flexible tube pump
US3726613A (en) * 1970-10-12 1973-04-10 Casimir W Von Pulsefree peristaltic pump
US3756752A (en) * 1971-12-20 1973-09-04 G Stenner Peristaltic pump
US3913636A (en) * 1973-04-10 1975-10-21 Ei Mochida Apparatus for automatically distributing a determined amount of liquid
US3935885A (en) * 1974-02-01 1976-02-03 Alter Richard R Capsule-filling machines
US4165954A (en) * 1975-08-11 1979-08-28 Corning Glass Works Linear peristaltic pump having pivotal pump arm
US4492531A (en) * 1982-04-30 1985-01-08 Kuraray Co., Ltd. Apparatus for producing a controlled pulsed liquid flow
US4976593A (en) * 1986-12-03 1990-12-11 Meddiss, Incorporated Pulsatile flow delivery apparatus
US5131823A (en) * 1990-03-28 1992-07-21 Orthoconcept S.A. Device for joining a connection piece to peristaltic pump
US5427274A (en) * 1992-07-23 1995-06-27 Wood; Robert Product delivery system for delivering sterile liquid product
US5431307A (en) * 1994-08-26 1995-07-11 Gencorp Inc. Dispensing plural components
US5640756A (en) * 1995-02-08 1997-06-24 Gencorp Inc. Manufacturing system
CN107269502A (zh) * 2017-05-18 2017-10-20 长沙执先智量科技股份有限公司 一种直线式高精度蠕动泵
CN107246380A (zh) * 2017-07-21 2017-10-13 长沙执先智量科技股份有限公司 一种直线式蠕动泵
CN107246379A (zh) * 2017-07-21 2017-10-13 长沙执先智量科技股份有限公司 一种直线式高精度蠕动泵
CN109098956A (zh) * 2018-09-30 2018-12-28 长沙执先智量科技股份有限公司 一种直线式洁净蠕动计量泵
EP3859154A4 (de) * 2018-09-30 2022-06-29 Hunan Zenithsun Technology Co., Ltd. Peristaltische dosierpumpe mit linearer reinigung
CN109098956B (zh) * 2018-09-30 2024-04-26 湖南执先科技有限公司 一种直线式洁净蠕动计量泵
WO2021086990A1 (en) * 2019-10-29 2021-05-06 Quantum-Si Incorporated Peristaltic pumping of fluids for bioanalytical applications and associated methods, systems, and devices
WO2021086985A1 (en) * 2019-10-29 2021-05-06 Quantum-Si Incorporated Peristaltic pumping of fluids and associated methods, systems, and devices
CN114901946A (zh) * 2019-10-29 2022-08-12 宽腾矽公司 用于生物分析应用的流体的蠕动泵送以及相关的方法、系统和装置
CN114930028A (zh) * 2019-10-29 2022-08-19 宽腾矽公司 流体的蠕动泵送以及相关联的方法、系统和装置
US12011716B2 (en) 2019-10-29 2024-06-18 Quantum-Si Incorporated Peristaltic pumping of fluids and associated methods, systems, and devices
WO2021188580A1 (en) * 2020-03-17 2021-09-23 Detect, Inc. Rapid diagnostic test
CN113117183A (zh) * 2021-04-21 2021-07-16 苏州市立医院 一种可调管径的蠕动泵配药机

Also Published As

Publication number Publication date
AT272843B (de) 1969-07-25
BE692331A (de) 1967-06-16
SE328192B (de) 1970-09-07
GB1162961A (en) 1969-09-04
DE1653397A1 (de) 1971-07-08

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