US2856925A - Syringe structure - Google Patents

Syringe structure Download PDF

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Publication number
US2856925A
US2856925A US698658A US69865857A US2856925A US 2856925 A US2856925 A US 2856925A US 698658 A US698658 A US 698658A US 69865857 A US69865857 A US 69865857A US 2856925 A US2856925 A US 2856925A
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Prior art keywords
plunger
syringe
dose
barrel
dosage
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Expired - Lifetime
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US698658A
Inventor
Norman D Helmer
Fred H Easton
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EASTON
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EASTON
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Priority claimed from US558971A external-priority patent/US2869541A/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • A61M5/31595—Pre-defined multi-dose administration by repeated overcoming of means blocking the free advancing movement of piston rod, e.g. by tearing or de-blocking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31591—Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31573—Accuracy improving means

Definitions

  • The. present invention relates generally toA dispensing devices, and more particularly to an improved multiple dosage syringe that automatically indicates when each of a number of doses of predetermined volume has been dispensed therefrom.
  • the present application is a continuation-in-part of our Patent No. 2,764,981 entitled, Multiple Dosage Syringe, which issued October 2, 1956, and is a division of pending application entitled, Syringe Structure, tiled in the United States Patent Oice January 13, 1956 under Serial No. 558,971. v
  • yA present-day practice in marketing such fluid materials is to package four disposable syringes'iilled therewith in a suitable box, with each syringe being discarded after use.
  • Such disposable syringes are normally formed of a synthetic plastic material such as polyethylene, or the like.
  • Disposable syringes of the character described are convenient to use and assure that but a predetermined quantity of uid material will be administered as a dose.
  • one very real disadvantage of such disposable syringes resides in the fact that the dosage cost to the dairyman is unduly high.
  • y'l'he primary purpose in devising thev present invention is to provide a disposable syringe'that is not only as convenient to use as previously available plastic devices, but one that provides a lower per dose cost to the dairyman in that the cost of each syringe is prorated over four doses rather than one.
  • a major object of the present invention is to furnish a multiple dosage syringe that automatically indicates when a dose of predetermined volume has been dispensed therefrom, and one that in structure is but slightly more complicated than the structure of those disposable syringes employed heretofore in the administration of single doses.
  • Another object of the invention is to furnish a multiple dosage syringe that so operates asto impart a signal to the feel of the user that a dose of predetermined volume has been dispensed therefrom in the dark or in poorly illuminated areas.
  • a further object of the invention is to supply a syringe that permits multiple doses of any desired number to be discharged therefrom by simple manual operations on the part of the user.
  • a still further object of the invention is to provide a multiple dose syringe that lowers the per dose cost of the uid material dispensed thereby to the extent that this mode of administration will create an ever'increasing demand therefor.
  • Yet another object of the invention is to provide a syringe, the use of which is directed toward the dairy industry, but which is equally adapted for use in the human field, by merely replacing the used needle with a sterilized needle each time a dose is administered.
  • Figure 1 is a perspective View of a first form of the invention
  • Figure 2 is a fragmentary perspective view of the.
  • plunger used in the first form of the invention showing one of the dosage-indicating devices mounted thereon;
  • Figure 3 is a fragmentary perspective view of a second form of dosage-indicating device.
  • Figure 4 is a longitudinally extending vertical crossforwardly in barrel A by means of plunger B, uid contained in the barrel is discharged ⁇ through a suitable projecting tubular member or hollow needle C.
  • barrel A includes an elongate tubular shell that is provided with an outwardly extending ring.
  • the forward end portionof shell 100 tapers inwardly.
  • the rear end'of tubular member C terminates in a nut 116 which is adapted to removably engage and be supported on the threaded tube 114.
  • nut 116 and tube 114 are so engaged,fbarrel A and member C are held together as a rigid integral unit.
  • the plunger B as may best be seen in Figure 1, includes a piston 120 that is slidably mounted within the confines of shell 100, and is sufficiently long to project from the shell, even when piston l120 is at its forwardmost position therein.
  • Plunger B ( Figures l and 2),
  • plunger B is defined by four normally disposed legs 124, 126, 128 and 130.
  • the rear extremity of plunger B terminates in a transversely positioned handle 132 that is preferably in shape of an annular plate, but may take any desired configuration.
  • Leg has a number of longitudinally spaced, downwardly extending recesses 144 formed therein, with each recessed portion being adapted to slidably receive an inverted U-shaped stop 146.
  • Stop 146 is formed with two downwardly extending legs 148 and 150 which are connected by a web 152. Web 152 projects upwardly above leg 130 to the extent that the forward face of the web contacts flange 112 whenplunger B is advanced forwardly to discharge a dose of medicament from the device.
  • a dose of medicament can only be discharged from barrel A by removing the forwardmost stop 146 from its position on plunger B. Removal of stop 146 is a simple operation, and'is achieved by merely flipping or slipping the U-shaped stop from its mounted position in the recess 144.
  • the number of stops that are removed as the stops are advanced forwardly toward flange 112 determines the quantity of medicament that can be discharged from tubular member C.
  • FIG. 3 A second form of the invention is shown in Figure 3 which differs from the first form only in lthe structure and design of the plunger E.
  • Plunger E is of the same generally elongate shape as plunger B, and is formed from four normally disposed legs 124a, 126e, 128a and 130:1.
  • Leg 13011 has a number of longitudinally spaced transverse bores formed therein, and each bore is of such size as to snugly support a transversely positioned pin 142.
  • Each pin 142 is suiciently long as to extend outwardly far enough from leg 130a to permit forward Patented Oct. 21, 1958 movement of plunger E.
  • theD forwardmost pin 142 is slidably removed from its supporting bore 140 by the .use of the thumb or forengen.
  • each bore 140 may have a pin 142 removably mounted' therein, or a single'pin 142 canV be'providedwhich' in turn is successively disposed iireach bore as plunger B is advanced forwardly; It wil1 ⁇ be apparent that irrespective of whether Vene or a ⁇ number of'fpins' T42' are used, successive dosesl ofpredeterminedA volume canlbe discharged at will fromthe invention',
  • This second form of theV invention differs' primarily from the' rst form thereof in'that legA 13021 can bel fabricated' from' a rigid plastic material rather than one embodyingtheresilient" characteristics requiredin the first formof the device:
  • a third form of the invention is' showniin' Figure 4l
  • This'form of the device is identical to the first formother than it includes a plunger G that' is formed from four normally disposed legs 12411, 12617, 12811', and 130]).
  • Groups of longitudinally spaced,A vertically aligned slots ⁇ 154 are formed in these legs, with each group of slots" being adapted to removably supporta resilientliand'. 156, as shown in Figure 4.
  • When"disp'osedi11oneofV the groups of slots 154, band 156 impedes forward movement ofplunger G by contacting the rear face of flange 122, thus limiting the dosage dispensed to a' predetermined quantity.
  • the resilient band is displaced from slot 154 in which it is 'positioned and"rolled"bacl i vention can be varied, and particularly the transverse cross--sectionof the plunger, whichmay becircular orother desired configuration.
  • A. multipler dosage huid-holding syringe comprising: an elongate barrel; fluid discharge meansmounted on one end of said barrel and in communication with the interior thereof; a piston slidably mounted in said barrel; a plunger securedto said piston and projecting outwardly from said barrelffrom the end thereofsopposite that on; which said fluid discharge meansis-V mounted, said plunger having; a plurality of longitudinally, spaced, transversely positionedy bores formed therein; andstopmeans capable ⁇ of' being; removably supported in.v saidl bores, with said stopv means beingof'such length as to consecutively contact the endof said barrel to'limit1-the movement? ofsaidplunger and piston toward; saidfdischarge means until ⁇ the contactinglone ofsaid. stop,r meansis manually removed from said b'ore inwhich it is disposed,

Description

oct-'21, 195s liar, s
, INVENTORS',
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SYRINGE STRUCTURE Norman D. Helmer, Long Beach, and Fre d H. Easton, Garden Grove, Calif.; said Helmer asslgnor to said Easton 3 Claims. (Cl. 12S-218) The. present invention relates generally toA dispensing devices, and more particularly to an improved multiple dosage syringe that automatically indicates when each of a number of doses of predetermined volume has been dispensed therefrom. The present application is a continuation-in-part of our Patent No. 2,764,981 entitled, Multiple Dosage Syringe, which issued October 2, 1956, and is a division of pending application entitled, Syringe Structure, tiled in the United States Patent Oice January 13, 1956 under Serial No. 558,971. v
In the dairy industry, cows frequently are infected by mastitis, a disease which is combated by the injection of certain fluid materials into the teats by means of av syringe. yA present-day practice in marketing such fluid materials is to package four disposable syringes'iilled therewith in a suitable box, with each syringe being discarded after use. Such disposable syringes are normally formed of a synthetic plastic material such as polyethylene, or the like.
Disposable syringes of the character described are convenient to use and assure that but a predetermined quantity of uid material will be administered as a dose. However, one very real disadvantage of such disposable syringes resides in the fact that the dosage cost to the dairyman is unduly high.
y'l'he primary purpose in devising thev present invention is to provide a disposable syringe'that is not only as convenient to use as previously available plastic devices, but one that provides a lower per dose cost to the dairyman in that the cost of each syringe is prorated over four doses rather than one.
A major object of the present invention is to furnish a multiple dosage syringe that automatically indicates when a dose of predetermined volume has been dispensed therefrom, and one that in structure is but slightly more complicated than the structure of those disposable syringes employed heretofore in the administration of single doses.
Another object of the invention is to furnish a multiple dosage syringe that so operates asto impart a signal to the feel of the user that a dose of predetermined volume has been dispensed therefrom in the dark or in poorly illuminated areas.
A further object of the invention is to supply a syringe that permits multiple doses of any desired number to be discharged therefrom by simple manual operations on the part of the user.
A still further object of the invention is to provide a multiple dose syringe that lowers the per dose cost of the uid material dispensed thereby to the extent that this mode of administration will create an ever'increasing demand therefor.
Yet another object of the invention is to provide a syringe, the use of which is directed toward the dairy industry, but which is equally adapted for use in the human field, by merely replacing the used needle with a sterilized needle each time a dose is administered.
These and other objects and advantages of .the invenl States Patent 2 tion will become apparent from the following description of a rst and certain alternate forms thereof, and from the drawing illustrating same in which:
Figure 1 is a perspective View of a first form of the invention; l
Figure 2 is a fragmentary perspective view of the.
plunger used in the first form of the invention showing one of the dosage-indicating devices mounted thereon;r
Figure 3 is a fragmentary perspective view of a second form of dosage-indicating device; and
Figure 4 is a longitudinally extending vertical crossforwardly in barrel A by means of plunger B, uid contained in the barrel is discharged `through a suitable projecting tubular member or hollow needle C. In structure, barrel A includes an elongate tubular shell that is provided with an outwardly extending ring.
shaped flange 112 situated on the rearward end thereof.
The forward end portionof shell 100 tapers inwardly.
to develop into a short tube 114, on the exterior surface of which threads are formed.
The rear end'of tubular member C terminates in a nut 116 which is adapted to removably engage and be supported on the threaded tube 114. When nut 116 and tube 114 are so engaged,fbarrel A and member C are held together as a rigid integral unit.
The plunger B, as may best be seen in Figure 1, includes a piston 120 that is slidably mounted within the confines of shell 100, and is sufficiently long to project from the shell, even when piston l120 is at its forwardmost position therein. Plunger B (Figures l and 2),
is defined by four normally disposed legs 124, 126, 128 and 130. The rear extremity of plunger B terminates in a transversely positioned handle 132 that is preferably in shape of an annular plate, but may take any desired configuration.
Leg has a number of longitudinally spaced, downwardly extending recesses 144 formed therein, with each recessed portion being adapted to slidably receive an inverted U-shaped stop 146. Stop 146 is formed with two downwardly extending legs 148 and 150 which are connected by a web 152. Web 152 projects upwardly above leg 130 to the extent that the forward face of the web contacts flange 112 whenplunger B is advanced forwardly to discharge a dose of medicament from the device. A dose of medicament can only be discharged from barrel A by removing the forwardmost stop 146 from its position on plunger B. Removal of stop 146 is a simple operation, and'is achieved by merely flipping or slipping the U-shaped stop from its mounted position in the recess 144. The number of stops that are removed as the stops are advanced forwardly toward flange 112 determines the quantity of medicament that can be discharged from tubular member C.
A second form of the invention is shown in Figure 3 which differs from the first form only in lthe structure and design of the plunger E. Plunger E is of the same generally elongate shape as plunger B, and is formed from four normally disposed legs 124a, 126e, 128a and 130:1. Leg 13011 has a number of longitudinally spaced transverse bores formed therein, and each bore is of such size as to snugly support a transversely positioned pin 142. Each pin 142 is suiciently long as to extend outwardly far enough from leg 130a to permit forward Patented Oct. 21, 1958 movement of plunger E. When it is desired to discharge a dose` of"medicanient'A from the invention; theD forwardmost pin 142 is slidably removed from its supporting bore 140 by the .use of the thumb or forengen.
and the plunger'E then advanced"totdisehargethe dose:
Each pink 142 isv sli'd'ably removed from' the bores as above mentioned, with the numberof doses ofY medica'- ment discharged fromtubularmember C. inA practice,
each bore 140 may have a pin 142 removably mounted' therein, or a single'pin 142 canV be'providedwhich' in turn is successively disposed iireach bore as plunger B is advanced forwardly; It wil1`be apparent that irrespective of whether Vene or a` number of'fpins' T42' are used, successive dosesl ofpredeterminedA volume canlbe discharged at will fromthe invention', This second form of theV invention differs' primarily from the' rst form thereof in'that legA 13021 can bel fabricated' from' a rigid plastic material rather than one embodyingtheresilient" characteristics requiredin the first formof the device:
A third form of the invention is' showniin'Figure 4l This'form of the deviceis identical to the first formother than it includes a plunger G that' is formed from four normally disposed legs 12411, 12617, 12811', and 130]). Groups of longitudinally spaced,A vertically aligned slots `154 are formed in these legs, with each group of slots" being adapted to removably supporta resilientliand'. 156, as shown in Figure 4. When"disp'osedi11oneofV the groups of slots 154, band 156 impedes forward movement ofplunger G by contacting the rear face of flange 122, thus limiting the dosage dispensed to a' predetermined quantity. However, when suicient pressurei's exerted on plunger G, the resilient band is displaced from slot 154 in which it is 'positioned and"rolled"bacl i vention can be varied, and particularly the transverse cross--sectionof the plunger, whichmay becircular orother desired configuration.
Although the forms of the invention herein shown and described are fully capable of achieving the objects and providing the advantages hereinbefore mentioned, it is to be understood that they are merely examples of the present embodiments-thereof and that we do not mean tobezlimited to the details of construction herein shownv and described.` otherk than as defined in the appended claims.
We claim:
1. A. multipler dosage huid-holding syringe, comprising: an elongate barrel; fluid discharge meansmounted on one end of said barrel and in communication with the interior thereof; a piston slidably mounted in said barrel; a plunger securedto said piston and projecting outwardly from said barrelffrom the end thereofsopposite that on; which said fluid discharge meansis-V mounted, said plunger having; a plurality of longitudinally, spaced, transversely positionedy bores formed therein; andstopmeans capable` of' being; removably supported in.v saidl bores, with said stopv means beingof'such length as to consecutively contact the endof said barrel to'limit1-the movement? ofsaidplunger and piston toward; saidfdischarge means until` the contactinglone ofsaid. stop,r meansis manually removed from said b'ore inwhich it is disposed,
2.xArmultiple dosage syringe as defined. in-claii'n-:l wherein said stop means is atleast oneelongate member that can be manuallydisposed in any one of said bores..
3; A multiple dosage syringe as defined in claixrry 1; whereinsaid stop; means isal plurality of elongate members-mounted insaid bores.
References:Citedd in the4 file of thispatent UNITED STATES PATENTS 2,373,520 Wallin Apr. 10;.1945f 2,474,496 Rayman a June 28, 1949' 2,571,653 Bastien a Oct'. 163.1951' 2,578,812 Kollsman Dec. 18;,1951' 2,607,343 Sarver Aug;I 19, 1952i. 2,629,517 Slobinl Febty 24; 11953 2,707,954V Kas,v Sr ,May'10,219552 ein
US698658A 1956-01-13 1957-11-25 Syringe structure Expired - Lifetime US2856925A (en)

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US558971A US2869541A (en) 1956-01-13 1956-01-13 Syringe structure
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Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3563240A (en) * 1966-07-20 1971-02-16 Jules Silver Dual unit syringe
FR2394299A1 (en) * 1977-06-16 1979-01-12 Silver Jules ADJUSTABLE DOSAGE SYRINGE
US4245654A (en) * 1977-03-22 1981-01-20 Concord Laboratories, Inc. Blood sampling syringe
US4874385A (en) * 1987-12-16 1989-10-17 Sherwood Medical Company Plunger lock device
US4946069A (en) * 1987-10-10 1990-08-07 Ing. Erich Pfeiffer Gmbh & Co. Kg Dispenser for manually discharging flowable media
US5385558A (en) * 1993-09-03 1995-01-31 Maxxim Medical, Inc. Angiographic control syringe
US5811061A (en) * 1992-02-10 1998-09-22 Baxter International Inc. Method and device for testing blood units for viral contamination
WO2002026298A2 (en) 2000-09-28 2002-04-04 Bayer Healthcare Llc Adjustable dosage syringe
WO2003057288A1 (en) * 2001-12-28 2003-07-17 Terumo Kabushiki Kaisha Pre-filled syringe
US20050131354A1 (en) * 2001-12-28 2005-06-16 Terumo Kabushiki Kaisha Syringe
US20070225656A1 (en) * 2006-03-24 2007-09-27 Hoyle John D Jr Dosage Control Syringe
WO2011097742A1 (en) 2010-02-12 2011-08-18 Medmix Systems Ag Discharge device having a locking element
US20150129442A1 (en) * 2012-05-21 2015-05-14 Baxter International Inc. Syringe storage tray
WO2022049080A1 (en) * 2020-09-01 2022-03-10 Janssen Pharmaceutica, N.V. Drug syringes with a mechanical stop for a second dose

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2373520A (en) * 1944-12-02 1945-04-10 Wallin Loren Hypodermic syringe
US2474496A (en) * 1947-06-26 1949-06-28 Rayman Lawrence Syringe
US2571653A (en) * 1950-02-25 1951-10-16 Bastien Victor Gerard Syringe
US2578812A (en) * 1947-12-20 1951-12-18 Kollsman Paul Injection syringe
US2607343A (en) * 1951-05-02 1952-08-19 American Viscose Corp Syringe pipette
US2629517A (en) * 1951-07-18 1953-02-24 David N Slobin Caulking gun with attaching means for replaceable carton
US2707954A (en) * 1954-05-05 1955-05-10 Sr John L Kas Dosing syringe

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2373520A (en) * 1944-12-02 1945-04-10 Wallin Loren Hypodermic syringe
US2474496A (en) * 1947-06-26 1949-06-28 Rayman Lawrence Syringe
US2578812A (en) * 1947-12-20 1951-12-18 Kollsman Paul Injection syringe
US2571653A (en) * 1950-02-25 1951-10-16 Bastien Victor Gerard Syringe
US2607343A (en) * 1951-05-02 1952-08-19 American Viscose Corp Syringe pipette
US2629517A (en) * 1951-07-18 1953-02-24 David N Slobin Caulking gun with attaching means for replaceable carton
US2707954A (en) * 1954-05-05 1955-05-10 Sr John L Kas Dosing syringe

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3563240A (en) * 1966-07-20 1971-02-16 Jules Silver Dual unit syringe
US4245654A (en) * 1977-03-22 1981-01-20 Concord Laboratories, Inc. Blood sampling syringe
FR2394299A1 (en) * 1977-06-16 1979-01-12 Silver Jules ADJUSTABLE DOSAGE SYRINGE
US4946069A (en) * 1987-10-10 1990-08-07 Ing. Erich Pfeiffer Gmbh & Co. Kg Dispenser for manually discharging flowable media
US4874385A (en) * 1987-12-16 1989-10-17 Sherwood Medical Company Plunger lock device
US5811061A (en) * 1992-02-10 1998-09-22 Baxter International Inc. Method and device for testing blood units for viral contamination
US5385558A (en) * 1993-09-03 1995-01-31 Maxxim Medical, Inc. Angiographic control syringe
WO2002026298A2 (en) 2000-09-28 2002-04-04 Bayer Healthcare Llc Adjustable dosage syringe
US6562007B1 (en) 2000-09-28 2003-05-13 Bayer Healthcare Llc Adjustable dosage syringe
US20050131354A1 (en) * 2001-12-28 2005-06-16 Terumo Kabushiki Kaisha Syringe
WO2003057288A1 (en) * 2001-12-28 2003-07-17 Terumo Kabushiki Kaisha Pre-filled syringe
US7261704B2 (en) 2001-12-28 2007-08-28 Terumo Kabushiki Kaisha Syringe
US20070265580A1 (en) * 2001-12-28 2007-11-15 Terumo Kabushiki Kaisha Syringe
US7427276B2 (en) 2001-12-28 2008-09-23 Terumo Kabushiki Kaisha Syringe
US20070225656A1 (en) * 2006-03-24 2007-09-27 Hoyle John D Jr Dosage Control Syringe
US7470259B2 (en) 2006-03-24 2008-12-30 Hoyle Jr John D Dosage control syringe
WO2011097742A1 (en) 2010-02-12 2011-08-18 Medmix Systems Ag Discharge device having a locking element
US20150129442A1 (en) * 2012-05-21 2015-05-14 Baxter International Inc. Syringe storage tray
US9808570B2 (en) 2012-05-21 2017-11-07 Baxalta Incorporated Syringe storage tray
US9889248B2 (en) * 2012-05-21 2018-02-13 Baxalta GmbH Syringe storage tray
WO2022049080A1 (en) * 2020-09-01 2022-03-10 Janssen Pharmaceutica, N.V. Drug syringes with a mechanical stop for a second dose

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