US2717599A - Needle structure - Google Patents

Needle structure Download PDF

Info

Publication number
US2717599A
US2717599A US272025A US27202552A US2717599A US 2717599 A US2717599 A US 2717599A US 272025 A US272025 A US 272025A US 27202552 A US27202552 A US 27202552A US 2717599 A US2717599 A US 2717599A
Authority
US
United States
Prior art keywords
needle
point
cannula
channel
outlet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US272025A
Inventor
Huber Jennie
Original Assignee
Huber Jennie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Huber Jennie filed Critical Huber Jennie
Priority to US272025A priority Critical patent/US2717599A/en
Priority to FR1070729T priority
Priority claimed from US471665A external-priority patent/US2717600A/en
Application granted granted Critical
Publication of US2717599A publication Critical patent/US2717599A/en
Anticipated expiration legal-status Critical
Application status is Expired - Lifetime legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3286Needle tip design, e.g. for improved penetration

Description

Sept. 13, 1955 HUBER 2,717,599

NEEDLE STRUCTURE Filed Feb. 18, 1952 INVENTOR.

PqL PH L. HUBER HTTUIEI EYJ United States Patent NEEDLE STRUCTURE Ralph L. Huber, Seattle, 'Wash.; Jennie Huber, administratrix of said Ralph L. Huber, deceased Application February 18, 1952, Serial No. 272,025

7 Claims. (Cl. 128221) This invention relates to improvements in tubular needles and cannulas that are designed to be projected into or through layers of flesh and tissue for hypodermic injection, or to puncture a stopper or other piercea'ble material forming a pharmaceutical closure such .as used in a blood storage vessel.

More particularly, the invention has reference to improvements in needles of those kinds having the point forming portion thereof angularly bent relative to the axial line of the cannula and the outlet of the channel opening to the side of the point forming portion. As an example of such needles, reference is directed to that of my U. S. patent issued on October 22, 1946, under No. 2,409,979 wherein the needle point is formed by first beveling the end of the cannula and then bending the point defining portion thereof laterally at such an angle that the beveled surface is brought parallel with ,the axial line of the cannula and flush with the longitudinal side edge of the cannula toward which the point is bent. in so bending the needle point, the channel of the cannula is likewise angularly deflected, and the opening therefrom as defined in the flat beveled surface will then open to the side of the point forming portion. If the bending of the point be of any lesser extent than provided for and shown in my above patent, the sharpened top edge of the channel outlet will be unprotected and tissue plug cutting will result when the needle is projected into the flesh.

It is an object of this invention to provide an improved form of needle, wherein all the advantages provided for in the formation of the point of the needle of my prior patent are retained and other advantages are gained; whereby the needle is made applicable to more uses; whereby objectionable plug cutting in any use of the needle will be eliminated, even in needles having the point forming portion bent laterally to a substantially lesser degree than in the needle of the above patent; whereby the tendency of needle deflection in puncturing a pharmaceutical closure is eliminated and hindrance to or disadvantages in use of a stylet, that results from .the point bending operation, is overcome.

Another object of this invention is .to so recess the heel end portion of the outlet of the needle channel that a stylet of substantially the full diameter of the channel can be employed and passed through the [needle channel without causing any outward deflection of the heel defining portion of the needle outlet, this extending of the outlet along the cannulabeing effected in such manner that use of the needle is in no way hindered and tissue or plug cutting thereby is avoided.

In accomplishing the above mentioned and .other objects of the invention, I have provided the improved details of construction, the preferred forms of which are illustrated in the accompanying drawings, wherein Fig. 1 is an enlarged, side view of a needle embodying the improvements of the present invention therein;

Figs. 2, 3 and 4 are enlarged longitudinal sectional views of the pointed end portion of a cannula, showing respectively, successive steps taken in the formation of the needle point;

Fig. 5 is a view of the pointed end portion of the needle as seen from the outlet side of the point and particularly illustrating the recessing of the cannula wall; and

Fig. 6 is an enlarged sectional view of a needle with a point like that of my previously mentioned prior patent, as recessed to permit the easy use therein of a stylet of the full diameter of the channel.

The commonly used types of hypodermic needles are formed with points by beveling the ends of the cannulas at an angle of about twenty degrees relative to their axial lines. In such needles, the channel of each cannula is straight from end to end and the outlet therefrom opens in the axial direction of the needle and from the beveled surface. Needles having their points so formed have certain disadvantages, one of which is that of tissue plug cutting. By means of the present teachings, this dimculty is overcome and a needle is provided through the bore of which a stylet may be introduced and which needle may also be efiiciently employed in the piercing of pharmaceutical type closures and stoppers.

More specifically stated, the advantages and objects of the present invention reside in the manner of relieving or cutting away the material of the cannula that forms the heel portion across the top edge of the outlet in needles which have the point forming portion angularly bent laterally to any degree that .is lesser than shown in my prior patent.

Referring more in detail to the drawings- In Fig. 1, I have shown in .an enlarged side view, a needle embodying the features of the present invention. In order to impart a better understanding, it will be explained that the needle point is formed by a succession of operations on a cannula, 10. The first operation may consist of cutting off or beveling the end of the cannula 10 at an angle of about 15 degrees relative to its axial line, thus to give it the beveled form shown in Fig. 2.

The second step in formation of the point has been illustrated in Fig. 3, and it preferably consists in bending the beveled point forming portion laterally, thus causing the channel of the cannula to be similarly bent or angularly deflected and the outlet 11 of the channel, which opens through the beveled surface, to be faced angularly or laterally of the axial line aa of the cannula body. This bending of the point forming portion can be to more or lesser degree, but it is now preferred that the piercing end of the beveled portion of the cannula, that is, the extreme point, as herein designated by numeral 12, be brought approximately to the axial line of the cannula.

The needle may be used in the form shown in Fig. 3 and due to the fact that the beveled surface is substantially flat, having a cutting edge defining its sides, and also due to the fact that it inclines towards the extended axial line of the cannula body at a relatively small angle, plugging is substantially eliminated. However, it is noted by reference to Fig. 3, that the bend of the point starts at a location, designated at 14, that is substantially opposite the top or heel forming ,p'ortion about the channel outlet. This rather abrupt bending of the cannula, notedbest in Figs. 3 and 4, places .the angular back wall port-ion of the needle point in a position at which it offers an obstruction to an easy and direct passing of a stylet through the channel beyond the location of the bend. In Fig. 3, a stylet is designated at .numeral 15 and the hindrance to its being projected through the channel by As a consequence of such hindrance, a stylet of substantially lesser diameter than the channel must be used, but use of such has its objections and disadvantages.

In order to overcome these above noted difficulties and disadvantages in use of a stylet and to provide that a stylet of substantially full diameter can be passed through this type of needle and beyond the point, I have, according to the objects of this invention, relieved, recessed or cut away the top edge forming portion of the channel outlet, that is, I cut away or recess that portion designated at 16, in Figs. 2 and 3, defining the top edge of the outlet 11 to a predetermined depth as illustrated in Fig. 5, depending on the angle to which the needle point is bent. In Fig. the normal top edge boundary of the outlet, as defined by the sharp cutting edge 13 shown in Fig. 3 is indicated by the dotted line xand the recess formed by cutting away the heel and part of the cannula wall is designated by numeral 17. It is noted that the recess extends away from the point somewhat beyond the point 14 where the needle channel starts to bend. The position of this point may be varied.

To insure against tissue cutting by the top edge of the recess, it is rounded off as at 18. Thus, although the top edge of the outlet is, in this specific form of needle, unprotected by the extending point forming portion of the needle, the rounding off of this edge is of such character that its exposure is not objectionable, nor is it a hindrance to use of the needle. By so relieving or recessing the heel end of the channel outlet, a stylet 15 of full size can be passed through the channel; this being due to the fact that a sufficient length of stylet passes beyond the base of the recess before its end engages the curve or bend of the needle point forming wall. Accordingly it can bend in conformity with the angular surface of the needle point as has been indicated in Fig. 4. Aside from the provision for use of a full sized stylet, the present needle, as shown in Figs. 1 and 4, has no tendency to be deflected laterally when pressed through a stopper or pharmaceutical closure, this being due to the fact that the point is substantially in the axial line of the needle and the beveled side surface and the back wall surface of the point are substantially at the same degree relative to the axial line of the cannula, as shown in Fig. 4.

It is not the intent, however, that the extent of the bending of the point be limited to that shown in Fig. 3, but it is anticipated that it might be somewhat less or go beyond that shown even to the extent shown in Fig. 6. Therefore, it is not the intent that the invention shall be confined in scope to the angular position of the point as shown in Fig. 4, but that the invention shall apply to bending of the point to any degree between the opposite side limits of the cannula body that is, to any extent between the position of the points 12 as seen in Figs. 2 and 6.

Also, it is not the intent that the relieving or recessing of the heel shall be to any definite extent, but shall be governed by the requirements of the particular needle and results desired to be accomplished.

Having thus described my invention, what I claim as new therein, and desire to secure by Letters Patent, is:

1. A needle structure comprising a cannula body with an angular bend near its end and a substantially flat inclined surface extending across the bent portion and having cutting edges defining its sides, said surface starting substantially at the start of the bend, at the inside of the angle, and inclined toward the extended axial line of the cannula body.

2. A needle structure comprising a cannula body with an angular bend near its end, and a substantially flat inclined surface extending across the bent portion and having cutting edges defining its sides, said surface extending from a point substantially at the start of the bend at the inside of the angle and inclined toward the extended axial line of the cannula body at an angle approximately equal to that at which the cannula body is bent.

3. A needle structure comprising a tubular cannula body with an angular bend near its end, and a substantially flat inclined surface extending obliquely across the bent portion and having cutting edges defining its sides, said surface continuing from a point substantially at the start of the bend at the inside of the angle and inclined toward the extended axial line of the cannula body; the channel of the cannula opening through said surface and having the heel portion of its bounding edge relieved to cause bluntness of the edge.

4. A needle structure comprising a tubular cannula body with an angular bend near its end, and an inclined surface extending obliquely across the bent portion, from a point that is substantially at the start of the bend at the inside of the angle and inclined toward the extended axial line of the cannula body; the channel of the cannula opening through said surface and there being a recess formed in the tubular body extending from the top edge of the outlet of the channel, away from the point.

5. A hypodermic needle and stylet combination; said needle comprising a cannula formed near its end with an angular bend and having a beveled surface extending obliquely across the bent portion from the start of the bend, at the inside thereof, toward the extended axial line of the cannula body and containing the outlet of the channel of the cannula therein, and there being a recess formed in the cannula wall, extending from the top edge of the channel outlet as defined in said beveled surface, to a substantial distance along the channel, and formed to the full diameter of the channel; said stylet being of substantially the full diameter of the channel and extended through the channel and from the outlet.

6. A hypodermic needle comprising a cannula formed near its end with an angular bend and having a beveled surface extending obliquely across the bent portion from the start of the bend, at the inside thereof, toward the extended axial line of the cannula body and containing the outlet of the channel of the cannula therein, and there being a recess formed in the cannula wall, extending from the top edge of the channel outlet as defined in said beveled surface, to a substantial distance along the channel, and formed to the full diameter of the channel; and having its bounding edges rounded to avoid tissue cutting when projected into the flesh.

7. A hypodermic needle including a cannula body having an angularly extending end portion having sharpened side edges and being flat throughout its major surface, said end portion terminating in a piercing point lying substantially in line with the axis of said body, the cannula bore being exposed through a zone beginning short of said point and continuing through to a body edge located adjacent a line short of that at which the angularity of said end portion is initiated and said edge being rounded in the direction of said point.

References Cited in the file of this patent UNITED STATES PATENTS 2,562,129 Scherer et al July 24, 1951 FOREIGN PATENTS 577,367 France June 4, 1924 620,780 Great Britain Mar. 30, 1949 965,711 France Feb. 22, 1950

US272025A 1952-02-18 1952-02-18 Needle structure Expired - Lifetime US2717599A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US272025A US2717599A (en) 1952-02-18 1952-02-18 Needle structure
FR1070729T 1953-02-10

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US272025A US2717599A (en) 1952-02-18 1952-02-18 Needle structure
FR1070729D FR1070729A (en) 1952-02-18 1953-02-10 hypodermic needle
US471665A US2717600A (en) 1952-02-18 1954-11-24 Needle structure

Publications (1)

Publication Number Publication Date
US2717599A true US2717599A (en) 1955-09-13

Family

ID=32095153

Family Applications (1)

Application Number Title Priority Date Filing Date
US272025A Expired - Lifetime US2717599A (en) 1952-02-18 1952-02-18 Needle structure

Country Status (2)

Country Link
US (1) US2717599A (en)
FR (1) FR1070729A (en)

Cited By (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2746454A (en) * 1953-05-04 1956-05-22 Hans W Sorensen Intravenous needle
US2904045A (en) * 1958-04-14 1959-09-15 Owings Thomas Hypodermic needles
US3064651A (en) * 1959-05-26 1962-11-20 Henderson Edward Hypodermic needle
US4889529A (en) * 1987-07-10 1989-12-26 B. Braun Melsungen Ag Needle
DE3915215A1 (en) * 1989-05-05 1990-11-08 Moehring Klaus Geraet for inserting an elongated body cavity belongings into human or animal organs or
DE4101231A1 (en) * 1991-01-17 1992-07-23 Fresenius Ag cannula
DE4109864A1 (en) * 1991-03-26 1992-10-08 Johann Dr Med Rull Stamp-free injection cannula for medical and industrial use - prevents pus formation due to so-called plastics punctures, and works on basis of cannula points being fully enclosed
US5515871A (en) * 1990-09-28 1996-05-14 Sulzer Brothers Ltd. Hollow needle for medical use and a laser method for manufacturing
DE19512607A1 (en) * 1995-04-04 1996-10-10 Johann Dr Med Rull Completely tragmentationsfreie cannulas
US20020106813A1 (en) * 2001-01-26 2002-08-08 Symyx Technologies, Inc. Apparatus and methods for parallel processing of multiple reaction mixtures
US20020110493A1 (en) * 1998-08-13 2002-08-15 Symyx Technologies , Inc Apparatus and methods for parallel processing of multiple reaction mixtures
US6443929B1 (en) 1996-02-27 2002-09-03 Injectimed, Inc. Needle tip guard for hypodermic needles
US6500157B2 (en) * 1998-09-03 2002-12-31 Ronald B. Luther Intravenous infusion needle with soft body
US6629959B2 (en) 1996-02-27 2003-10-07 Injectimed, Inc. Needle tip guard for percutaneous entry needles
US6802199B2 (en) 1999-02-04 2004-10-12 Integ, Inc. Needle for body fluid tester
US20040241875A1 (en) * 2001-01-26 2004-12-02 Symyx Technologies, Inc. Apparatus and methods for parallel processing of multiple reaction mixtures
US20050215977A1 (en) * 2004-03-25 2005-09-29 Uschold John E Needles and methods of using same
US20060178646A1 (en) * 2005-02-04 2006-08-10 Chad Harris Non-coring needles and methods of manufacturing same
US20070123935A1 (en) * 2005-11-30 2007-05-31 Myers Gene E Method and apparatus for contemporaneous formation of a body structure opening and homologous pedicle
US20070293873A1 (en) * 2006-06-19 2007-12-20 Allergan, Inc. Apparatus and methods for implanting particulate ocular implants
US20080097335A1 (en) * 2006-08-04 2008-04-24 Allergan, Inc. Ocular implant delivery assemblies
US20090264813A1 (en) * 2006-06-19 2009-10-22 Allergan, Inc. Apparatus and methods for implanting particulate ocular implants
US20100185205A1 (en) * 2009-01-16 2010-07-22 Allergan, Inc. Interocular injector
US7867215B2 (en) 2002-04-17 2011-01-11 Carmel Pharma Ab Method and device for fluid transfer in an infusion system
USD637713S1 (en) 2009-11-20 2011-05-10 Carmel Pharma Ab Medical device adaptor
US7942860B2 (en) 2007-03-16 2011-05-17 Carmel Pharma Ab Piercing member protection device
US7975733B2 (en) 2007-05-08 2011-07-12 Carmel Pharma Ab Fluid transfer device
US8029747B2 (en) 2007-06-13 2011-10-04 Carmel Pharma Ab Pressure equalizing device, receptacle and method
US8075550B2 (en) 2008-07-01 2011-12-13 Carmel Pharma Ab Piercing member protection device
US8162013B2 (en) 2010-05-21 2012-04-24 Tobias Rosenquist Connectors for fluid containers
US8273056B2 (en) 2011-02-28 2012-09-25 Injectimed, Inc. Needle guard with resilient spring surrounding tip shield
US8287513B2 (en) 2007-09-11 2012-10-16 Carmel Pharma Ab Piercing member protection device
US8328772B2 (en) * 2003-01-21 2012-12-11 Carmel Pharma Ab Needle for penetrating a membrane
US8414539B1 (en) 2011-12-27 2013-04-09 B. Braun Melsungen Ag Needle tip guard for percutaneous entry needles
US20130116556A1 (en) * 2011-11-05 2013-05-09 Custom Medical Applications Neural safety injection system and related methods
US8480646B2 (en) 2009-11-20 2013-07-09 Carmel Pharma Ab Medical device connector
WO2013104642A1 (en) * 2012-01-09 2013-07-18 Fresenius Kabi Deutschland Gmbh Port cannula for puncturing port catheters
US8523838B2 (en) 2008-12-15 2013-09-03 Carmel Pharma Ab Connector device
US8545475B2 (en) 2002-07-09 2013-10-01 Carmel Pharma Ab Coupling component for transmitting medical substances
US8562583B2 (en) 2002-03-26 2013-10-22 Carmel Pharma Ab Method and assembly for fluid transfer and drug containment in an infusion system
US8622985B2 (en) 2007-06-13 2014-01-07 Carmel Pharma Ab Arrangement for use with a medical device
US8657803B2 (en) 2007-06-13 2014-02-25 Carmel Pharma Ab Device for providing fluid to a receptacle
US8672895B2 (en) 2011-02-28 2014-03-18 Injectimed, Inc. Needle guard
EP2711080A1 (en) * 2012-09-24 2014-03-26 Siemens Healthcare Diagnostics Products GmbH Hollow needle for a sample pipettor
US8790330B2 (en) 2008-12-15 2014-07-29 Carmel Pharma Ab Connection arrangement and method for connecting a medical device to the improved connection arrangement
US8827978B2 (en) 2007-09-17 2014-09-09 Carmel Pharma Ab Bag connector
CN104721911A (en) * 2015-03-05 2015-06-24 倪治法 Nondestructive anti-falling puncture needle
US9168203B2 (en) 2010-05-21 2015-10-27 Carmel Pharma Ab Connectors for fluid containers
US20160338734A1 (en) * 2015-05-22 2016-11-24 Dexcom, Inc. Needle for transcutaneous analyte sensor delivery
US20170119974A1 (en) * 2015-11-04 2017-05-04 Custom Medical Applications, Inc. Needles and related assemblies and methods
US9668725B2 (en) 2015-03-24 2017-06-06 Richard B. Beaven Laparoscopic wound closure device
US10398834B2 (en) 2007-08-30 2019-09-03 Carmel Pharma Ab Device, sealing member and fluid container

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2481930A1 (en) * 1980-05-06 1981-11-13 Villette Alain Hypodermic needle having coaxial point - for ease of insertion by rotary drill without plugging

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR577367A (en) * 1923-04-13 1924-09-04 Improvements to the needles for injections
GB620780A (en) * 1945-11-05 1949-03-30 Menthen Willem Improvements in and relating to hypodermic syringe needles
FR965711A (en) * 1950-09-20
US2562129A (en) * 1946-01-23 1951-07-24 Scherer Corp R P Hypodermic syringe

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR965711A (en) * 1950-09-20
FR577367A (en) * 1923-04-13 1924-09-04 Improvements to the needles for injections
GB620780A (en) * 1945-11-05 1949-03-30 Menthen Willem Improvements in and relating to hypodermic syringe needles
US2562129A (en) * 1946-01-23 1951-07-24 Scherer Corp R P Hypodermic syringe

Cited By (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2746454A (en) * 1953-05-04 1956-05-22 Hans W Sorensen Intravenous needle
US2904045A (en) * 1958-04-14 1959-09-15 Owings Thomas Hypodermic needles
US3064651A (en) * 1959-05-26 1962-11-20 Henderson Edward Hypodermic needle
US4889529A (en) * 1987-07-10 1989-12-26 B. Braun Melsungen Ag Needle
DE3915215A1 (en) * 1989-05-05 1990-11-08 Moehring Klaus Geraet for inserting an elongated body cavity belongings into human or animal organs or
US5403296A (en) * 1989-05-05 1995-04-04 Mohring; Klaus Puncturing instrument
US5515871A (en) * 1990-09-28 1996-05-14 Sulzer Brothers Ltd. Hollow needle for medical use and a laser method for manufacturing
DE4101231A1 (en) * 1991-01-17 1992-07-23 Fresenius Ag cannula
DE4109864A1 (en) * 1991-03-26 1992-10-08 Johann Dr Med Rull Stamp-free injection cannula for medical and industrial use - prevents pus formation due to so-called plastics punctures, and works on basis of cannula points being fully enclosed
DE19512607A1 (en) * 1995-04-04 1996-10-10 Johann Dr Med Rull Completely tragmentationsfreie cannulas
US7534231B2 (en) 1996-02-27 2009-05-19 Injectimed, Inc. Needle tip guard for percutaneous entry needles
US8545454B2 (en) 1996-02-27 2013-10-01 B. Braun Melsungen Ag Needle tip guard for percutaneous entry needles
US6443929B1 (en) 1996-02-27 2002-09-03 Injectimed, Inc. Needle tip guard for hypodermic needles
US8444605B2 (en) 1996-02-27 2013-05-21 B. Braun Melsungen Ag Needle tip guard for percutaneous entry needles
US7927314B2 (en) 1996-02-27 2011-04-19 B. Bran Melsungen AG Needle tip guard for percutaneous entry needles
US20060189934A1 (en) * 1996-02-27 2006-08-24 Kuracina Thomas C Needle tip guard for percutaneous entry needles
US6629959B2 (en) 1996-02-27 2003-10-07 Injectimed, Inc. Needle tip guard for percutaneous entry needles
US20020110493A1 (en) * 1998-08-13 2002-08-15 Symyx Technologies , Inc Apparatus and methods for parallel processing of multiple reaction mixtures
US6913934B2 (en) * 1998-08-13 2005-07-05 Symyx Technologies, Inc. Apparatus and methods for parallel processing of multiple reaction mixtures
US6500157B2 (en) * 1998-09-03 2002-12-31 Ronald B. Luther Intravenous infusion needle with soft body
US6863662B2 (en) 1998-09-03 2005-03-08 Ronald B. Luther Intravenous infusion needle with soft body
US20040236249A1 (en) * 1999-02-04 2004-11-25 Hilgers Michael Edward Needle for body fluid tester
US6802199B2 (en) 1999-02-04 2004-10-12 Integ, Inc. Needle for body fluid tester
US20040241875A1 (en) * 2001-01-26 2004-12-02 Symyx Technologies, Inc. Apparatus and methods for parallel processing of multiple reaction mixtures
US7858049B2 (en) 2001-01-26 2010-12-28 Freeslate, Inc. Apparatus and methods for parallel processing of multiple reaction mixtures
US20080138260A1 (en) * 2001-01-26 2008-06-12 Symyx Technologies, Inc Apparatus and methods for parallel processing of multiple reaction mixtures
US20020106813A1 (en) * 2001-01-26 2002-08-08 Symyx Technologies, Inc. Apparatus and methods for parallel processing of multiple reaction mixtures
US7335513B2 (en) 2001-01-26 2008-02-26 Symyx Technologies, Inc. Apparatus and methods for parallel processing of multiple reaction mixtures
US20030195479A1 (en) * 2001-04-30 2003-10-16 Kuracina Thomas C. Needle tip guard for percutaneous entry needles
US6860871B2 (en) 2001-04-30 2005-03-01 Injectimed, Inc. Needle tip guard for percutaneous entry needles
US8562583B2 (en) 2002-03-26 2013-10-22 Carmel Pharma Ab Method and assembly for fluid transfer and drug containment in an infusion system
US10123938B2 (en) 2002-03-26 2018-11-13 Carmel Pharma Ab Method and assembly for fluid transfer and drug containment in an infusion system
US7867215B2 (en) 2002-04-17 2011-01-11 Carmel Pharma Ab Method and device for fluid transfer in an infusion system
US8545475B2 (en) 2002-07-09 2013-10-01 Carmel Pharma Ab Coupling component for transmitting medical substances
US9039672B2 (en) 2002-07-09 2015-05-26 Carmel Pharma Ab Coupling component for transmitting medical substances
US8328772B2 (en) * 2003-01-21 2012-12-11 Carmel Pharma Ab Needle for penetrating a membrane
US20050215977A1 (en) * 2004-03-25 2005-09-29 Uschold John E Needles and methods of using same
US7645268B2 (en) * 2004-03-25 2010-01-12 Boston Scientific Scimed, Inc. Needles and methods of using same
US20060178646A1 (en) * 2005-02-04 2006-08-10 Chad Harris Non-coring needles and methods of manufacturing same
US7651482B2 (en) * 2005-02-04 2010-01-26 Boston Scientific Scimed, Inc. Non-coring needles and methods of manufacturing same
US20070123935A1 (en) * 2005-11-30 2007-05-31 Myers Gene E Method and apparatus for contemporaneous formation of a body structure opening and homologous pedicle
US8668676B2 (en) * 2006-06-19 2014-03-11 Allergan, Inc. Apparatus and methods for implanting particulate ocular implants
US20070293873A1 (en) * 2006-06-19 2007-12-20 Allergan, Inc. Apparatus and methods for implanting particulate ocular implants
US20090264813A1 (en) * 2006-06-19 2009-10-22 Allergan, Inc. Apparatus and methods for implanting particulate ocular implants
US20080097335A1 (en) * 2006-08-04 2008-04-24 Allergan, Inc. Ocular implant delivery assemblies
US9039761B2 (en) 2006-08-04 2015-05-26 Allergan, Inc. Ocular implant delivery assemblies with distal caps
US7942860B2 (en) 2007-03-16 2011-05-17 Carmel Pharma Ab Piercing member protection device
US8381776B2 (en) 2007-03-16 2013-02-26 Carmel Pharma Ab Piercing member protection device
US8225826B2 (en) 2007-05-08 2012-07-24 Carmel Pharma Ab Fluid transfer device
US7975733B2 (en) 2007-05-08 2011-07-12 Carmel Pharma Ab Fluid transfer device
US9309020B2 (en) 2007-06-13 2016-04-12 Carmel Pharma Ab Device for providing fluid to a receptacle
US8029747B2 (en) 2007-06-13 2011-10-04 Carmel Pharma Ab Pressure equalizing device, receptacle and method
US8622985B2 (en) 2007-06-13 2014-01-07 Carmel Pharma Ab Arrangement for use with a medical device
US8657803B2 (en) 2007-06-13 2014-02-25 Carmel Pharma Ab Device for providing fluid to a receptacle
US10398834B2 (en) 2007-08-30 2019-09-03 Carmel Pharma Ab Device, sealing member and fluid container
US8287513B2 (en) 2007-09-11 2012-10-16 Carmel Pharma Ab Piercing member protection device
US8926583B2 (en) 2007-09-11 2015-01-06 Carmel Pharma Ab Piercing member protection device
US8827978B2 (en) 2007-09-17 2014-09-09 Carmel Pharma Ab Bag connector
US8075550B2 (en) 2008-07-01 2011-12-13 Carmel Pharma Ab Piercing member protection device
US8523838B2 (en) 2008-12-15 2013-09-03 Carmel Pharma Ab Connector device
US8790330B2 (en) 2008-12-15 2014-07-29 Carmel Pharma Ab Connection arrangement and method for connecting a medical device to the improved connection arrangement
US8545554B2 (en) 2009-01-16 2013-10-01 Allergan, Inc. Intraocular injector
US20100185205A1 (en) * 2009-01-16 2010-07-22 Allergan, Inc. Interocular injector
USD637713S1 (en) 2009-11-20 2011-05-10 Carmel Pharma Ab Medical device adaptor
US8480646B2 (en) 2009-11-20 2013-07-09 Carmel Pharma Ab Medical device connector
US9168203B2 (en) 2010-05-21 2015-10-27 Carmel Pharma Ab Connectors for fluid containers
US8336587B2 (en) 2010-05-21 2012-12-25 Carmel Pharma Ab Connectors for fluid containers
US8162013B2 (en) 2010-05-21 2012-04-24 Tobias Rosenquist Connectors for fluid containers
US9610403B2 (en) 2011-02-28 2017-04-04 Injectimed, Inc. Needle guard
US9440052B2 (en) 2011-02-28 2016-09-13 Injectimed, Inc. Needle guard
US8821439B2 (en) 2011-02-28 2014-09-02 Injectimed Inc. Needle guard
US9399119B2 (en) 2011-02-28 2016-07-26 Injectimed, Inc. Needle guard
US8764711B2 (en) 2011-02-28 2014-07-01 Injectimed, Inc. Needle guard
US8273056B2 (en) 2011-02-28 2012-09-25 Injectimed, Inc. Needle guard with resilient spring surrounding tip shield
US8672895B2 (en) 2011-02-28 2014-03-18 Injectimed, Inc. Needle guard
US9238104B2 (en) 2011-02-28 2016-01-19 Injectimed, Inc. Needle guard
US20130116556A1 (en) * 2011-11-05 2013-05-09 Custom Medical Applications Neural safety injection system and related methods
US8414539B1 (en) 2011-12-27 2013-04-09 B. Braun Melsungen Ag Needle tip guard for percutaneous entry needles
WO2013104642A1 (en) * 2012-01-09 2013-07-18 Fresenius Kabi Deutschland Gmbh Port cannula for puncturing port catheters
CN103889487B (en) * 2012-01-09 2017-04-12 费森尤斯卡比德国有限公司 Port cannula for puncturing port catheters
CN103889487A (en) * 2012-01-09 2014-06-25 费森尤斯卡比德国有限公司 Port cannula for puncturing port catheters
EP2711080A1 (en) * 2012-09-24 2014-03-26 Siemens Healthcare Diagnostics Products GmbH Hollow needle for a sample pipettor
US10040060B2 (en) 2012-09-24 2018-08-07 Siemens Healthcare Diagnostics Products Gmbh Hollow needle for a sample pipettor
CN104721911A (en) * 2015-03-05 2015-06-24 倪治法 Nondestructive anti-falling puncture needle
US10349926B2 (en) * 2015-03-24 2019-07-16 Modern Surgical Solutions Llc Laparoscopic wound closure device
US9668725B2 (en) 2015-03-24 2017-06-06 Richard B. Beaven Laparoscopic wound closure device
US20160338733A1 (en) * 2015-05-22 2016-11-24 Dexcom, Inc. Needle for transcutaneous analyte sensor delivery
US20160338628A1 (en) * 2015-05-22 2016-11-24 Dexcom, Inc. Needle for transcutaneous analyte sensor delivery
US20160338734A1 (en) * 2015-05-22 2016-11-24 Dexcom, Inc. Needle for transcutaneous analyte sensor delivery
US20170119974A1 (en) * 2015-11-04 2017-05-04 Custom Medical Applications, Inc. Needles and related assemblies and methods

Also Published As

Publication number Publication date
FR1070729A (en) 1954-08-10

Similar Documents

Publication Publication Date Title
US3394704A (en) Surgical needle with bonded suture
US3608539A (en) Method for the biopsy of subcutaneous masses
US3536073A (en) Catheter placement apparatus
US3524566A (en) Straw slot for container closure
US3530492A (en) Method and apparatus for administering hypodermic injections
US3406687A (en) Guide and positioning means for a needle
US5630802A (en) Device for introducing a catheter into a body cavity
US7108709B2 (en) Surgical staple
US6193694B1 (en) Needle point protection sheath
US5824002A (en) Trocar-cannula device
US2847995A (en) Transfusion needle sheath
EP0858351B1 (en) Anti-coring needle
US4411657A (en) Hypodermic needle
JP3702408B2 (en) Needle protection sheath
US3175554A (en) Split biopsy needle
US4935008A (en) Double lumen introducing needle
EP0383426B1 (en) Recessed dilator-sheath assembly and method for making same
US4079738A (en) Needle restraining apparatus
EP0269763B1 (en) A set of double needles for injecting liquid medicine
US5591132A (en) Epidural catheter
US3330268A (en) Biopsy needle
EP0780091B1 (en) Medical needle for penetrating body tissues
CA1282663C (en) Puncture needle assembly
US20020082546A1 (en) Infusion devices and method
US20080027387A1 (en) Cleveland round tip (CRT) needle