US231236A - Process for coating pills - Google Patents
Process for coating pills Download PDFInfo
- Publication number
- US231236A US231236A US231236DA US231236A US 231236 A US231236 A US 231236A US 231236D A US231236D A US 231236DA US 231236 A US231236 A US 231236A
- Authority
- US
- United States
- Prior art keywords
- pills
- gelatine
- solution
- coating
- glue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000006187 pill Substances 0.000 title description 30
- 238000000034 method Methods 0.000 title description 14
- 239000011248 coating agent Substances 0.000 title description 10
- 238000000576 coating method Methods 0.000 title description 10
- 239000001828 Gelatine Substances 0.000 description 24
- 229920000159 gelatin Polymers 0.000 description 24
- 235000019322 gelatine Nutrition 0.000 description 24
- 239000003292 glue Substances 0.000 description 10
- 241000206672 Gelidium Species 0.000 description 6
- 108010059642 isinglass Proteins 0.000 description 6
- 229910052627 muscovite Inorganic materials 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 235000021388 linseed oil Nutrition 0.000 description 4
- 239000000944 linseed oil Substances 0.000 description 4
- 239000003921 oil Substances 0.000 description 4
- 235000019198 oils Nutrition 0.000 description 4
- 229940037003 alum Drugs 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 239000004833 fish glue Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000004540 pour-on Substances 0.000 description 2
- 238000005096 rolling process Methods 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 235000015041 whisky Nutrition 0.000 description 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/005—Coating of tablets or the like
Definitions
- the pills should be made very smooth before applying the gelatine solution, which latter should be used hot, while the oil should only be warm, as if used hot it would remove The pan and pills should also be warm.
- a solution of alum and whisky or alcohol may be used in place of the oil, if desired, to prevent the gelatine from sticking the pills together, or to separate the pills after the gelatine is applied.
Description
UNITED STATES PATENT OFFICE.
JOHN P. NEMOURS, OF ST. LOUIS, MISSOURI, ASSIGNOR TO PARKE, DAVIS 86 (30., OF DETROIT, MICHIGAN.
PROCESS FOR COATING PILLS.
SPECIFICATION forming part of Letters Patent No. 231,236, dated August 1'7, 1880.
To all whom it may concern Be it known that I, JOHN PAUL NEMoURs, of St. Louis, in the county of St. Louis, Missouri, have invented an Improved Process for Coating Pills with Gelatine, of which the following is a specification.
The nature of this invention relates to that class of processes employed for coating pills with gelatine; and the invention consists in the peculiar process substantially as hereinafter set forth.
In carryingoutmyinvention,take of common or white glue or gelatine, as may be desired, a sufficient quantity, and soften the same in cold water until in condition to apply heat. Then bring gradually to a boil, until the gelatine or glue assumes a sirupy consistency. As a test for its condition for the purpose desired, dip in a spatula, and if, on exposure, the glue or gelatine sets quickly, then the pot may be removed from the fire, after the addition of isin glass, as hereinafter stated. Soften in cold water a quantity of American isin glass, (fish-glue,) add water, and boil till the solution is of the consistency of the solution of glue aforesaid. Before removing the glue or gelatine solution from the fire-I add to each pint thereof two table-spoonfuls of the isinglass solution and mix them thoroughly together, when the solution may be removed from the fire and is ready for use. Take a flat pan of convenient size and place therein the pills to be coated, then add four or five table-spoonfuls of the solution, prepared as above described, to every pound of pills.
I then, with the hand, roll the gelatine already applied.
Application filed January 30, 1879.
the pills around vigorously, also shaking the pan well, until the pills are well coated with the solution. At this stage of the process the pills are all stuck together in a mass. For the purpose of separating them I pour on quickly enough of linseed-oil, which I have previously boiled down to three-fourths its volume, to cover the pills, stirring well with the hands, and shaking the pan until the gelatine becomes cold and hard, when they are placed on a fine sieve to drain, repeating the process as often as may be necessary to obtain a sufficient coating on the pills.
The pills should be made very smooth before applying the gelatine solution, which latter should be used hot, while the oil should only be warm, as if used hot it would remove The pan and pills should also be warm.
A solution of alum and whisky or alcohol may be used in place of the oil, if desired, to prevent the gelatine from sticking the pills together, or to separate the pills after the gelatine is applied.
What I claim as my invention is- The process herein described of coating pills, consisting in first rolling them in a solution of hot gelatine, then separating them by agitation while immersed under a layer of warm linseed-oil, or its equivalent, and finally draining them, substantially as described.
JOHN P. NEMOURS.
Witnesses:
BERNARD F. MCDONALD, FRANCIS MEAGHER.
Publications (1)
Publication Number | Publication Date |
---|---|
US231236A true US231236A (en) | 1880-08-17 |
Family
ID=2300607
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US231236D Expired - Lifetime US231236A (en) | Process for coating pills |
Country Status (1)
Country | Link |
---|---|
US (1) | US231236A (en) |
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0
- US US231236D patent/US231236A/en not_active Expired - Lifetime
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