US20260097216A1 - Wireless stimulation control device, stent, wireless stimulation control system, wireless stimulation control method, and wireless stimulation control program - Google Patents

Wireless stimulation control device, stent, wireless stimulation control system, wireless stimulation control method, and wireless stimulation control program

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Publication number
US20260097216A1
US20260097216A1 US19/114,254 US202219114254A US2026097216A1 US 20260097216 A1 US20260097216 A1 US 20260097216A1 US 202219114254 A US202219114254 A US 202219114254A US 2026097216 A1 US2026097216 A1 US 2026097216A1
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US
United States
Prior art keywords
stimulation
living body
stent
basis
information
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
US19/114,254
Other languages
English (en)
Inventor
Kentaro Hayashi
Hirotaka IEKI
Yusuke Kondo
Daisuke Inagaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hicky Inc
Original Assignee
Hicky Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hicky Inc filed Critical Hicky Inc
Publication of US20260097216A1 publication Critical patent/US20260097216A1/en
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/375—Constructional arrangements, e.g. casings
    • A61N1/37516—Intravascular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/025—Digital circuitry features of electrotherapy devices, e.g. memory, clocks, processors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/3611—Respiration control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36135—Control systems using physiological parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36135—Control systems using physiological parameters
    • A61N1/36139—Control systems using physiological parameters with automatic adjustment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37211—Means for communicating with stimulators
    • A61N1/37217—Means for communicating with stimulators characterised by the communication link, e.g. acoustic or tactile
    • A61N1/37223—Circuits for electromagnetic coupling
    • A61N1/37229—Shape or location of the implanted or external antenna
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/378—Electrical supply
    • A61N1/3787—Electrical supply from an external energy source

Definitions

  • the present disclosure relates to a wireless stimulation control device, a stent, a wireless stimulation control system, a wireless stimulation control method, and a wireless stimulation control program.
  • a system which controls a device that has been implanted in a body by means of wireless power supply, which uses an electric field or magnetic field from outside a living body, to the device implanted in the body.
  • the device described in Patent Literature 1 supplies electric power to a medical device main body through a power supply coil having a cylindrical coil and an annular ring surrounding an outer circumference of the cylindrical coil, with this power supply coil being configured to wirelessly supply power to a power reception coil provided in the medical device main body, which is implanted in a living body, from outside the living body through electromagnetic induction.
  • a wireless stimulation control device includes: a living body analysis unit for generating, on the basis of living body information regarding a living body acquired from a sensor, living body analysis information indicating a result of analyzing the state of the living body; a stimulation control unit for generating, on the basis of the living body analysis information, stimulation control information regarding control of stimulation of a nearby nerve of an in vivo stent, with the stimulation using an induced current and being performed by the stent that is configured to generate the induced current on the basis of an electric field or magnetic field; and a wireless power supply unit for supplying, on the basis of at least one of the living body analysis information and the stimulation control information, an electric field or magnetic field to the stent so as to generate the induced current.
  • a wireless stimulation control method includes, with a computer: generating, on the basis of living body information regarding a living body acquired from a sensor, living body analysis information indicating a result of analyzing a state of the living body; generating, on the basis of the living body analysis information, stimulation control information regarding control of stimulation of a nearby nerve of an in vivo stent, with the stimulation using an induced current and beings performed by the stent that is configured to generate the induced current on the basis of an electric field or magnetic field; and supplying, on the basis of at least any of the living body analysis information and the stimulation control information, an electric field or magnetic field to the stent so as to generate the induced current.
  • a wireless stimulation control program causes a computer to implement: a living body analysis unit for generating, on the basis of living body information regarding a living body acquired from a sensor, living body analysis information indicating a result of analyzing a state of the living body; a stimulation control unit for generating, on the basis of the living body analysis information, stimulation control information regarding control of stimulation of a nearby nerve of an in vivo stent, with the stimulation using an induced current and being performed by the stent that is configured to generate an induced current on the basis of an electric field or magnetic field; and a wireless power supply unit for supplying, on the basis of at least one of the living body analysis information and the stimulation control information, an electric field or magnetic field to the stent so as to generate the induced current.
  • unit not only signifies physical means but also includes cases where functions of the “unit” are implemented by software.
  • functions of one “unit” or device may be implemented by two or more physical means, devices or pieces of software, and moreover functions of two or more “units” or devices may be implemented by one physical means, one device, or one piece of software.
  • a wireless stimulation control device a wireless stimulation control method, and a wireless stimulation control program that can perform control according to the state of a living body.
  • FIG. 1 is a diagram showing an overview of processing in a wireless stimulation control system 100 according to an embodiment of the present disclosure.
  • FIG. 2 is a diagram showing the configuration of the wireless stimulation control system 100 according to an embodiment of the present disclosure.
  • FIG. 3 is a diagram showing an example of living body information stored in a storage unit 210 .
  • FIG. 4 is a diagram showing an example of living body analysis information stored in the storage unit 210 .
  • FIG. 5 is a diagram showing an example of stimulation control information stored in the storage unit 210 .
  • FIG. 6 is a diagram showing an example of stimulation of a nearby nerve performed by a stent 300 .
  • FIG. 7 is a sequence chart showing an example of processing in the wireless stimulation control system 100 .
  • FIG. 8 is a sequence chart showing an example of processing in the wireless stimulation control system 100 .
  • FIG. 1 is a diagram showing an overview of processing in a wireless stimulation control system 100 according to an embodiment of the present disclosure.
  • the wireless stimulation control device 200 includes, for example, a pad 201 attached to a living body.
  • the wireless stimulation control device 200 acquires living body information regarding a living body from a sensor (for example, a sensor included in the pad 201 ).
  • the wireless stimulation control device 200 analyzes the living body information and supplies to the in vivo stent 300 an electric field or magnetic field 202 through the pad 201 , so as to generate an induced current.
  • the pad 201 has the function of a sensor, and acquires living body information, and a function of supplying an electric field or magnetic field.
  • the sensor function and the function of supplying an electric field or magnetic field may be implemented by the same means (for example, the pad 201 ), or may be implemented by separate means.
  • the stent 300 is introduced into the body (for example, into a blood vessel 400 ). Near the stent 300 , there is a nerve 500 .
  • the stent 300 generates an induced current on the basis of the electric field or magnetic field 202 , and performs stimulation of the nerve 500 by using the induced current.
  • the wireless stimulation control system 100 can be applied, for example, to patients with sleep apnea syndrome.
  • the wireless stimulation control device 200 acquires respiration information regarding the respiration of a patient from a sensor, for example.
  • the wireless stimulation control device 200 analyzes the living body information, and supplies an electric field or magnetic field 202 to the stent 300 , which is placed in a blood vessel 400 (for example, a phrenic vein) near a nerve 500 (for example, the phrenic nerve) of the patient, through a pad 201 , so as to generate an induced current.
  • the wireless stimulation control device 200 supplies the electric field or magnetic field 202 to the stent 300 , for example, when the patient's breathing has stopped or is unstable.
  • the stent 300 then generates an induced current on the basis of the electric field or magnetic field 202 , and the stent 300 performs stimulation on the nerve 500 by using the induced current. This causes the patient's diaphragm to move and the patient's breathing resumes or stabilizes.
  • wireless stimulation control system can also be applied to individuals other than patients with sleep apnea syndrome.
  • FIG. 2 is a diagram showing the configuration of the wireless stimulation control system 100 according to an embodiment of the present disclosure.
  • the wireless stimulation control system 100 includes the wireless stimulation control device 200 and the stent 300 .
  • the wireless stimulation control device 200 is an information processing device that analyzes living body information and supplies an electric field or magnetic field to the stent 300 , so as to generate an induced current.
  • the wireless stimulation control device 200 includes a storage unit 210 , a living body information acquisition unit 220 , a living body analysis unit 230 , a stimulation control unit 240 , a wireless power supply unit 250 and a stimulation instruction unit 260 .
  • Each unit of the wireless stimulation control device 200 can be implemented, for example, by using a storage area or by a processor executing a program stored in the storage area.
  • the stent 300 is a stent placed in the body and configured to generate an induced current on the basis of an electric field or a magnetic field.
  • the stent 300 stimulates, in response to the electric field or magnetic field supplied from the wireless stimulation control device 200 , a nearby nerve by using an induced current.
  • the stent 300 includes, for example, a cylindrical structure made of metal.
  • the stent 300 can, for example, expand a tubular portion (for example, a lumen such as a blood vessel) in the body from inside by means of the cylindrical structure.
  • the stent 300 may be expanded by a balloon or may expand without a balloon (so-called self-expansion) by pressing against the vessel wall, for example.
  • the stent 300 includes a conductor portion that allows a current to flow and an insulator portion that does not allow a current to flow.
  • the stent 300 may have conductors at both ends and an insulator at a central part. Specifically, electrodes attached to both ends of the stent 300 may function as conductors.
  • the stent 300 includes a power reception unit 310 , a capacitor 320 , a stimulation instruction reception unit 330 , and a stimulation unit 340 .
  • the stent 300 in the present embodiment may consist solely of a stent main body (for example, a cylindrical structure main body made of metal) or may include a stent main body (for example, a cylindrical structure main body made of metal) and certain additional parts. That is, functions of each functional unit (for example, the power reception unit 310 , the capacitor 320 , the stimulation instruction reception unit 330 , and the stimulation unit 340 ) of the stent 300 may be implemented by the stent main body or by additional parts attached to the stent main body.
  • the stent main body, as well as the stent main body and the additional parts as a whole is simply referred to as the stent.
  • the living body in which the stent 300 is placed is not limited, and may, for example, be a human body.
  • the position where the stent 300 is placed is not limited, and may, for example, be within a blood vessel.
  • the storage unit 210 stores information processed in the wireless stimulation control device 200 .
  • the storage unit 210 can store, for example, living body information, living body analysis information and stimulation control information, which will be described below.
  • the living body information acquisition unit 220 acquires living body information regarding a living body from a sensor and stores same in the storage unit 210 .
  • the living body information acquisition unit 220 may acquire the living body information from, for example, a sensor attached to the chest of a living body or a sensor disposed near a living body (for example, the back of the living body or near the pillow). In addition, the living body information acquisition unit 220 may also acquire the living body information from, for example, a sensor provided in a space where a living body is located (for example, in a bedroom of the living body).
  • the living body information acquisition unit 220 may acquire respiration information regarding the respiration of the living body and take same as the living body information, for example.
  • the living body information includes, for example, time information and sensor information.
  • the time information is, for example, information indicating the time when the living body information acquisition unit 220 acquires the living body information from a sensor or the time when a sensor acquires the living body information.
  • the sensor information is information regarding a living body that is acquired by a sensor.
  • the sensor information may, for example, be acceleration information regarding an acceleration indicating the movement of a living body. That is, when a sensor is attached to the chest of a living body, the sensor information may be acceleration information indicating the up-and-down movement of the chest. Therefore, the sensor information may detect whether a living body undergoes respiration.
  • the sensor information may be any information regarding a living body that a sensor may acquire, such as the body temperature, pulse wave, or blood pressure of the living body, or the concentration of specific substances (for example, oxygen or carbon dioxide in blood or exhaled air) in the living body.
  • the sensor information may, for example, be information based on electromagnetic waves (for example, millimeter-wave radar) transmitted and received by a sensor.
  • the sensor function of a sensor may be implemented by the sensor included in the pad 201 attached to the living body, for example, or it may be implemented by other means.
  • the sensor may be located inside or outside the living body.
  • the sensor may also be included in the wireless stimulation control device 200 .
  • the sensor function, and a wireless power supply function of the wireless power supply unit 250 which will be described below, may be implemented by the same means (for example, the pad 201 ), or may be implemented by separate means.
  • the wireless power supply unit 250 may supply an electric field or magnetic field to the stent 300 on the basis of the stimulation control information.
  • the wireless power supply unit 250 can supply, on the basis of the stimulation control information, an electric field or magnetic field to the stent 300 for stimulation performed by the stent 300 at a timing indicated in the stimulation control information (particularly, the timing information), for example.
  • the wireless power supply unit 250 can supply an electric field or magnetic field to the stent 300 on the basis of the living body analysis information and the stimulation control information.
  • the wireless power supply unit 250 may supply, on the basis of the living body analysis information, an electric field or magnetic field to the stent 300 for stimulation performed by the stent 300 at a timing indicated in the stimulation control information (particularly, the timing information), when it is determined that stimulation is needed (for example, when the living body's breathing has stopped), for example.
  • the wireless power supply unit 250 can supply an electric field or a magnetic field to the stent 300 , thus providing electric power for stimulation performed by the stent 300 . Therefore, the wireless stimulation control device 200 and the stent 300 do not need to be connected by leads, such that the movement of the living body (such as a patient) into which the stent 300 is introduced is not limited by leads.
  • the stimulation instruction unit 260 supplies, on the basis of the stimulation control information, an electric field or magnetic field to the stent 300 so as to transmit a stimulation instruction signal that instructs the stimulation of a nearby nerve of the stent 300 .
  • the stimulation instruction signal is a signal transmitted from the wireless stimulation control device 200 to the stent 300 by means of an electric field or magnetic field (for example, electromagnetic induction).
  • the stent 300 can perform stimulation of a nearby nerve on the basis of the stimulation instruction signal.
  • the wireless stimulation control device 200 may not include the stimulation instruction unit 260 .
  • the wireless stimulation control device 200 may replace the wireless power supply by means of the wireless power supply unit 250 with the stimulation instruction signal. That is, the stimulation unit 340 of the stent 300 , which will be described below, can stimulate a nearby nerve of the stent 300 in response to the wireless power supply by means of the wireless power supply unit 250 (that is, for example, in response to the receiving of power by the power reception unit 310 of the stent 300 , which will be described below).
  • the power reception unit 310 receives power in response to an electric field or magnetic field for generating an induced current used for the stimulation of a nearby nerve of the stent 300 .
  • the power reception unit 310 receives power in response to the electric field or magnetic field supplied by the wireless power supply unit 250 of the wireless stimulation control device 200 , for example.
  • the power reception unit 310 is, for example, a metal coil, and can receive electric power in response to an electric field or magnetic field through electromagnetic induction.
  • the power reception unit 310 may be attached to the inner side of the cylindrical structure included in the stent 300 , or may be attached to other parts of the stent 300 .
  • the capacitor 320 stores electricity in response to the receiving of power by the power reception unit 310 .
  • the capacitor 320 may be implemented by components referred to, for example, as capacitors, condensers, or batteries.
  • the capacitor 320 may be attached, for example, to the inner side of the cylindrical structure included in the stent 300 .
  • the stent 300 may not include the capacitor 320 . In such case, as described below, the stent 300 may perform stimulation by means of the stimulation unit 340 in response to the receiving of power by the power reception unit 310 without storing electricity in response to the receiving of power by the power reception unit 310 .
  • the stimulation instruction reception unit 330 receives a stimulation instruction signal that instructs stimulation of the nearby nerve and is transmitted using an electric field or magnetic field.
  • the stimulation instruction reception unit 330 can receive a stimulation instruction signal transmitted by means of an electric field or magnetic field supplied by the stimulation instruction unit 260 of the wireless stimulation control device 200 , for example.
  • the stimulation instruction reception unit 330 may be implemented by an IC (Integrated Circuit) chip included in the stent 300 , for example.
  • the IC chip may be attached, for example, to the inner side of the cylindrical structure included in the stent 300 .
  • the stimulation unit 340 stimulates, in response to the receiving of power by the power reception unit 310 , a nearby nerve of the stent 300 by using an induced current generated on the basis of an electric field or magnetic field.
  • the stimulation unit 340 causes a current to flow, for example, from one conductor portion (for example, an electrode) in the stent 300 to the other conductor portion in response to the receiving of power by the power reception unit 310 .
  • one conductor portion for example, an electrode
  • one of the conductor portions is connected to the power reception unit 310 via a lead. Therefore, in response to the receiving of power by the power reception unit 310 , a current flows to this conductor portion through the lead. Then, the current flows to the other conductor portion via the nearby nerve of the stent 300 .
  • both ends of the stent 300 are conductors and the central part is an insulator, and a current flows from the conductor portion at one end of the stent 300 to the conductor portion at the other end thereof, the current cannot flow through the insulator portion at the central part, so the current flows via a nearby nerve. As a result, the nearby nerve is stimulated.
  • a current may also flow between the conductor portions of each of the multiple stents 300 .
  • a current flows through a conductor portion of one stent and a conductor portion of another stent, the current flows via the nearby nerve. As a result, the nearby nerve is stimulated.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Pulmonology (AREA)
  • Acoustics & Sound (AREA)
  • Electromagnetism (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Electrotherapy Devices (AREA)
US19/114,254 2022-09-22 2022-09-22 Wireless stimulation control device, stent, wireless stimulation control system, wireless stimulation control method, and wireless stimulation control program Pending US20260097216A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2022/035309 WO2024062586A1 (ja) 2022-09-22 2022-09-22 無線刺激制御装置、ステント、無線刺激制御システム、無線刺激制御方法、及び無線刺激制御プログラム

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US (1) US20260097216A1 (https=)
EP (1) EP4591923A1 (https=)
JP (1) JP7446654B1 (https=)
CN (1) CN119894575A (https=)
AU (1) AU2022479458A1 (https=)
WO (1) WO2024062586A1 (https=)

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Publication number Priority date Publication date Assignee Title
US8155744B2 (en) * 2007-12-13 2012-04-10 The Cleveland Clinic Foundation Neuromodulatory methods for treating pulmonary disorders
JP5575789B2 (ja) * 2008-11-19 2014-08-20 インスパイア・メディカル・システムズ・インコーポレイテッド 睡眠呼吸障害の治療方法
US8855783B2 (en) * 2011-09-09 2014-10-07 Enopace Biomedical Ltd. Detector-based arterial stimulation
US9452293B2 (en) * 2014-06-19 2016-09-27 Inspire Medical Systems, Inc. Hybrid communication channel for communicating with an implantable medical device
CN107949351A (zh) * 2015-03-30 2018-04-20 伊诺佩斯生物医药有限公司 用于血管内装置的天线
JP6632435B2 (ja) 2016-03-15 2020-01-22 株式会社パイオラックス 体内埋め込み型医療装置用の給電装置及び体内埋め込み型医療装置
FR3059557A1 (fr) * 2016-12-07 2018-06-08 Universite Grenoble Alpes Systeme implantable
TR201718704A2 (tr) * 2017-11-24 2017-12-21 T C Istanbul Aydin Ueniversitesi Hi̇pertansi̇yon tedavi̇si̇ i̇çi̇n bi̇r tansi̇yon algilayici ve düzenleyi̇ci̇ aorti̇k stent yapilanmasi
EP3927421A4 (en) * 2019-03-08 2022-11-23 Mayo Foundation for Medical Education and Research SYSTEMS AND METHODS FOR STIMULATION AND ABLATION OF THE STELLAT GANGLION
TW202103657A (zh) * 2019-07-24 2021-02-01 羅琮澧 呼吸中止症治療器
CN114401665A (zh) * 2019-07-25 2022-04-26 启迪医疗仪器公司 呼吸检测

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JP7446654B1 (ja) 2024-03-11
EP4591923A1 (en) 2025-07-30
JPWO2024062586A1 (https=) 2024-03-28
CN119894575A (zh) 2025-04-25
WO2024062586A1 (ja) 2024-03-28
AU2022479458A1 (en) 2025-05-01

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