US20220097879A1 - Method and device for sterilely enclosing a container - Google Patents

Method and device for sterilely enclosing a container Download PDF

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Publication number
US20220097879A1
US20220097879A1 US17/426,394 US202017426394A US2022097879A1 US 20220097879 A1 US20220097879 A1 US 20220097879A1 US 202017426394 A US202017426394 A US 202017426394A US 2022097879 A1 US2022097879 A1 US 2022097879A1
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US
United States
Prior art keywords
cap
container
tongs
region
conveying means
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US17/426,394
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English (en)
Inventor
Harald Reber
Patrick Schösser
Marcus Schwarze
Wolfgang Emmert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bausch and Stroebel Maschinenfabrik Ilshofen GmbH and Co KG
Original Assignee
Bausch and Stroebel Maschinenfabrik Ilshofen GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Assigned to Bausch + Ströbel Maschinenfabrik Ilshofen GmbH + Co. KG reassignment Bausch + Ströbel Maschinenfabrik Ilshofen GmbH + Co. KG ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: Schösser, Patrick, Emmert, Wolfgang, REBER, HARALD, Schwarze, Marcus
Publication of US20220097879A1 publication Critical patent/US20220097879A1/en
Abandoned legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B7/00—Closing containers or receptacles after filling
    • B65B7/16—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons
    • B65B7/28—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers
    • B65B7/2842—Securing closures on containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B43/00—Forming, feeding, opening or setting-up containers or receptacles in association with packaging
    • B65B43/42—Feeding or positioning bags, boxes, or cartons in the distended, opened, or set-up state; Feeding preformed rigid containers, e.g. tins, capsules, glass tubes, glasses, to the packaging position; Locating containers or receptacles at the filling position; Supporting containers or receptacles during the filling operation
    • B65B43/46—Feeding or positioning bags, boxes, or cartons in the distended, opened, or set-up state; Feeding preformed rigid containers, e.g. tins, capsules, glass tubes, glasses, to the packaging position; Locating containers or receptacles at the filling position; Supporting containers or receptacles during the filling operation using grippers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B53/00—Shrinking wrappers, containers, or container covers during or after packaging
    • B65B53/02—Shrinking wrappers, containers, or container covers during or after packaging by heat
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B7/00—Closing containers or receptacles after filling
    • B65B7/16—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons
    • B65B7/161—Sealing filled ampoules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D43/00—Lids or covers for rigid or semi-rigid containers
    • B65D43/02—Removable lids or covers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D77/00—Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks or bags
    • B65D77/003—Articles enclosed in rigid or semi-rigid containers, the whole being wrapped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D77/00—Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks or bags
    • B65D77/04—Articles or materials enclosed in two or more containers disposed one within another
    • B65D77/048—Articles or materials enclosed in two or more containers disposed one within another the inner and outer containers being rigid and the outer container being of curved cross-section, e.g. cylindrical
    • B65D77/0486—Articles or materials enclosed in two or more containers disposed one within another the inner and outer containers being rigid and the outer container being of curved cross-section, e.g. cylindrical the inner container being coaxially disposed within the outer container
    • B65D77/0493—Articles or materials enclosed in two or more containers disposed one within another the inner and outer containers being rigid and the outer container being of curved cross-section, e.g. cylindrical the inner container being coaxially disposed within the outer container and retained at a distance of the inner side-wall of the outer container, e.g. within a bottle neck
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B2220/00—Specific aspects of the packaging operation
    • B65B2220/16—Packaging contents into primary and secondary packaging

Definitions

  • the present invention relates to a method and a device for sterilely enclosing a container.
  • a sterile packaging of containers is necessary in particular in the pharmaceutical sector, since on the one hand corresponding medications should not be contaminated and on the other hand certain medications can be hazardous in the event of unintentional contact.
  • Vials, syringes or the like are generally used as containers.
  • a mechanised process and a corresponding device would be particularly advantageous in this case in order to enclose an individual corresponding container completely and in a sterilely sealing manner.
  • a user being able to immediately recognise from the container whether the sterile seal has been maintained since manufacture would be a further advantage.
  • the object of the present invention is therefore to specify a corresponding method and a corresponding device.
  • the method according to the invention for sterilely enclosing a container by means of at least two caps comprises at least the following steps:
  • the intermediate region is to be understood as the region which, when one cap is slipped onto the other, lies between the end of one cap and the outer wall of the other cap.
  • the gap region is to be understood as the region between the ends of the cap when no cap is slipped onto the other and a distance may even remain between the ends of the caps.
  • the gap region thus means both the distance that results when the first and second caps are not long enough to come into contact, as well as the region having possibly a narrow gap when the caps just meet one another or the second cap is slid on until the caps meet.
  • connection in a preferably sterilely sealing manner is preferably to be understood as meaning that this intermediate region and/or gap region is sealed off to such an extent that its permeability is almost equal to or equal to the permeability of the cap material.
  • adhesive materials, swelling materials and/or also thermal treatment and/or treatment with pressure come into consideration for this purpose, said treatment, for example, if the cap material of one cap can be bonded or adhesively bonded to the cap material of the other cap by corresponding heat and/or pressure.
  • Step h) can also take place spatially separately in a product manufacturing process. So that steps c) and e) are carried out, for example, in a plant/at a production site, the container is then moved to another location - if necessary, the container provided with the caps is packaged in a suitable and preferably sterile manner for transport - and then step h) is carried out in a further plant/at a further production site.
  • the general advantage of the method according to the invention is that the number of processing means or processing tools, such as tongs, which touch both the outside of the container and the outside of the caps, can be significantly reduced by appropriately coordinating the shape of the caps with one another and with respect to the container.
  • Any processing means or processing tool such as conveying means, tongs, conveyor belts, slides and the like that comes into contact both with the outside of the container and with the outside of the caps is therefore a source of risk for the transfer of hazardous substances that have accidentally come into contact with the outside of the container to the outside of the sterile sealing cap. This is also known as cross-contamination.
  • a user can also immediately see that the preferably sterile seal has been maintained since manufacuture.
  • the sealing film or also the outside of the cap can advantageously be provided with appropriate instructions for use, date of manufacture or quality and/or degree of contamination prevention.
  • the method according to the invention can also be used in cases in which there is no sterile seal after the caps have been put on, because then there is still the advantage that maximum sterility is ensured at least at the time the caps are put on. The maintenance of sterility therefore only depends on the subsequent handling of the container.
  • the method according to the invention can at least ensure that the containers are provided for this further processing in a sufficiently sterile manner and avoiding cross-contamination.
  • sealing film and/or the label can also be applied for reasons other than to indicate the avoidance of cross-contamination, for example product information, safety features or the like can be thereon, for example, to show the user a certain manufacturing standard or to make counterfeiting of products more difficult.
  • this can of course also be combined with the fact that the sealing film and/or the label simultaneously indicate that cross-contamination was avoided during filling.
  • Such properties can be recognised by a user in particular from whether the sealing film and/or the label are undamaged.
  • caps should overlap, should be slid on until they meet one another, or whether a distance is intended to remain between the ends of the caps depends substantially on how large the corresponding tolerance ranges have to be selected due to the expected deviations/inaccuracies in the cap size/shape, container size/shape and/or tong shape/movement.
  • the method according to the invention preferably further comprises one or more of the following steps:
  • steps x are preferably carried out together with the aforementioned steps of the method according to the invention in alphabetical order, with the exception of step x), which can be carried out several times and in particular between two other successive corresponding steps.
  • This is particularly preferably implemented by carrying out all of the aforementioned steps in alphabetical order, with the exception of the corresponding step x). This is a way of ensuring that no processing means/tool comes into contact with both the outside of the container and the outside of the enclosing caps.
  • first conveying means second conveying means, lifting tongs, first tongs and second tongs do not necessarily have to be objects that are physically completely separate from one another.
  • first conveying means second conveying means, lifting tongs, first tongs and second tongs
  • second conveying means lifting tongs
  • first tongs first tongs
  • second tongs do not necessarily have to be objects that are physically completely separate from one another.
  • the lifting tongs, the first tongs and/or the second tongs can also be part of the same transport rake comprising a plurality of tongs and/or in other embodiments the lifting tongs, the first tongs and/or the second tongs can be part of different transport rakes.
  • first and second tongs namely that corresponding portions of a transport rake and/or the same transport rake having tongs that correspond to the first and second tongs are only used as first and second tongs in the sense of the method and do not come into contact with the outside of the container and only with the caps.
  • a first transport rake is used for the method, which comprises lifting tongs in a first region and second tongs in a second region.
  • This first transport rake extends along one side of a whole conveying means.
  • a second transport rake generally comprising only half as many tongs, preferably extends, the tongs of which serve as the first tongs.
  • the transport rakes can also provide propulsion along the conveying means, with the corresponding transfer from the lifting tongs to the first tongs of the opposite or second transport rake transporting the containers further along the conveying direction by clamping the caps, in such a way that the second tongs of the first transport rake can clamp the container or the outside of the caps in the corresponding step.
  • a plurality of lifting tongs, first tongs and/or second tongs for the method according to the invention are preferably provided in order to process a plurality of containers simultaneously in accordance with any variant of the method according to the invention.
  • the lifting tongs, the first tongs, the second tongs and/or a transport rake comprising the lifting tongs, the first tongs and/or the second tongs are preferably rotated away from the container before and/or after gripping/clamping the container and/or one of the caps.
  • this can be technically advantageous to a lateral movement, in particular if rotating away takes place about an axis parallel to a direction of longitudinal extension of the first conveying means, the second conveying means and/or the transport rake(s).
  • transport rakes, lifting tongs, first tongs and/or second tongs are preferably movable along the conveying means.
  • the lifting tongs, the first tongs and/or the second tongs are preferably each formed by two jaws movable relative to one another, between which the container or the caps can be clamped.
  • the first and/or the second conveying means a conveyor belt, a combination of a transport surface and transport pushers, transport rakes and/or a transport container, for example a tub or a nest, are preferred.
  • the container is preferably a vial, a syringe or a similar container that can be used for medical products.
  • the first and/or the second cap is preferably designed as a cylinder open on one side and preferably circular or rectangular having a diameter greater than the largest diameter of the container, in the first or in the second region respectively.
  • the variant with cylinders open on one side is preferred, because then only the first and second caps have to be slid on, an intermediate region may have to be sealed and the container is completely enclosed by the two caps and, as a result of the sealed or isolating sealing connection between the two, the container is packed in a sufficiently sterile manner.
  • an advantageous variant of the method according to the invention provides that only the first cap is designed as a cylinder open on one side and the second cap as a cylinder open on both sides, the method further comprising the following steps:
  • the first cap is exposed as a cylinder open on one side at one end of a container and then second and further caps, which are designed as cylinders open on both sides, are slid onto the container one after the other until the container is so sufficiently covered with caps that a last cap, also designed as a cylinder open only on one side, can be slid on and then the container is in turn surrounded or enclosed by caps, possibly with the exception of intermediate and/or gap regions that have yet to be closed.
  • first and second tongs can also be designed in such a way that they alternately clamp the further caps put on one after the other and move the container accordingly so that further caps can be slid on.
  • the first, second and/or further caps and/or the sealing film preferably comprise a plastics material and/or another easily formable material and/or walls which, in terms of permeability, meet sterility requirements for medical products contained or filled in the container.
  • a device according to the invention can be designed in accordance with the technical features described above with regard to the method.
  • an embodiment that does not comprise any means for performing step h) comes into particular consideration, because in corresponding systems for filling pharmaceutical products, labelling/sealing/packing stations are often located in other systems/machines than the bottling itself.
  • one variant is to equip a device according to the invention without means for carrying out step h).
  • a further advantage of an embodiment of the method according to the invention or the device/machine according to the invention without step h) or without means for this is that the method/device according to the invention can then be used flexibly with regard to applications in which high value is placed on sterility and the avoidance of cross-contamination with regard to the application of the label/sealing film, as well as with regard to applications in which this is of lesser importance. Different devices then do not have to be provided for the two cases.
  • a device according to the invention for carrying out a method according to the invention preferably comprises:
  • the device according to the invention preferably further comprises:
  • a device according to the invention can preferably also be designed such that a plurality of lifting tongs, first tongs or transport rakes comprising second tongs are provided in each case.
  • a transport rake comprising lifting tongs and second tongs and to provide a further transport rake opposite on the other side of a conveying means comprising the first tongs.
  • the first cap, second cap and/or further caps are preferably not designed to be rigid, i.e. in particular, elastic and/or resilient to the extent that the caps yield to the clamping such that the inside of the caps comes into contact with the container at some points and the clamping force is thus transmitted to the container via the cap.
  • FIG. 1.1-1.15 show the implementation of a first embodiment of the method according to the invention with the aid of a device according to the invention, each in a schematic view in the direction of view along the conveying means;
  • FIGS. 2.1 and 2.2 show the steps corresponding to FIGS. 1.8 and 1.10 of a second embodiment of the method according to the invention with the aid of the same device according to the invention as in FIG. 1.1-1.15 , but using different caps.
  • FIG. 1.1 shows the situation at the beginning of an embodiment of the method according to the invention using an embodiment of the device according to the invention.
  • the container ( 40 ) has been brought to the work area of the lifting tongs ( 14 ) by means of a first conveying means ( 10 ), which is part of the device according to the invention, but can also be separate from it.
  • the lifting tongs ( 14 ) are aligned with their mutually movable jaws ( 16 , 18 ) on a second region ( 44 ) of the container ( 40 ).
  • FIG. 1.2 the jaws ( 16 , 18 ) of the lifting tongs ( 14 ) have been moved apart, pushed around the first cap, moved together and now clamp the second region ( 44 ) of the container ( 40 ).
  • FIG. 1.3 shows how the first cap ( 52 ) is lowered from above in relation to FIG. 1.3 onto the first region ( 42 ) of the container ( 40 ) located at the top.
  • the cap ( 52 ) can be held on the tube ( 60 ) during the lowering process by means of negative pressure.
  • the negative pressure has ended, and the cap ( 52 ) thus remains on the now covered first region ( 42 ) of the container ( 40 ).
  • the cap ( 52 ) is dimensioned and the attachment point of the lifting tongs ( 14 ) is selected so that there is no contact between the first cap ( 52 ) and the lifting tongs ( 14 ) and the jaws ( 16 , 18 ) thereof.
  • FIGS. 1.5 and 1.6 show how the first tongs ( 22 ) are brought in and the first cap ( 52 ) is clamped with the aid of the jaws thereof, which are constructed similarly to the jaws ( 16 , 18 ) of the lifting tongs ( 14 ).
  • the first tongs ( 22 ) now clamp the container ( 40 ), namely only by coming into contact with the cap ( 52 ) and without coming into contact with the actual body of the container ( 40 ).
  • FIGS. 1.7 and 1.8 show how the lifting tongs ( 14 ) are then removed from the container ( 40 ) and how the container ( 40 ) is moved with the aid of the first tongs ( 22 ) in relation to the first conveying means ( 10 ), which is designed, for example, as a conveyor belt, so that, in a similar manner as the first cap ( 52 ) was fed in from above, the second cap ( 54 ) can now be brought up to the container ( 40 ) from below and aligned with the second region ( 44 ) with the aid of the tube ( 62 ).
  • the cap ( 54 ) has an engagement element ( 56 ) on the outside, which can interact with a complementary engagement element on the inside or on the inner circumference of the cap ( 52 ).
  • the engagement element ( 56 ) can be, for example, an annular protrusion.
  • the diameter of the second cap ( 54 ) is slightly smaller than the diameter of the first cap ( 52 ), the first cap ( 52 ) slips over the second cap ( 54 ) and the engagement elements ( 56 ) engage with one another.
  • the second tongs ( 24 ) are brought up to clamp the second cap ( 54 ), whereby the container ( 40 ), which is now completely covered by the two caps ( 52 , 54 ), can be held by the second tongs ( 24 ).
  • the setting tube ( 62 ) is now moved downwards.
  • the first tongs ( 22 ) are removed from the cap ( 52 ) and moved away.
  • FIG. 1.11 shows how the sealing film ( 58 ) is now slid over the first cap ( 52 ) from above with the aid of the setting ring ( 59 ) until the state shown in FIG. 1.12 is reached, that the sealing film ( 58 ) exactly covers the transition region or gap region between the first cap ( 52 ) and the second cap ( 54 ).
  • the sealing film ( 58 ) is pressed against the two caps ( 52 , 54 ) with the aid of the setting ring ( 59 ) and adhesively bonded thereto in a sterilely sealing manner, for example by means of heat.
  • the sealing film or a label can also be applied to the gap region by unrolling.
  • a movement of a corresponding roll-off device around the container and a rotation of the container and/or a combination of both are conceivable. If the container is to be rotated, it may have to be moved onto a turntable or the like by means of the second tongs.
  • the application of the sealing film can also be omitted at this point and the provision of means for this, such as the setting ring ( 59 ) or roll-off devices, can be dispensed with.
  • the sealing film can, for example, also be applied subsequently using another machine.
  • the container ( 40 ) is isolated from its surroundings in a completely sterile, sealed manner.
  • FIGS. 1.13 to 1.15 now show how the setting ring ( 59 ) is moved upwards again and, with the aid of the second tongs ( 24 ), the completely covered container ( 40 ) is deposited on a second conveying means ( 12 ), here for example a trough of a nest.
  • the caps are dimensioned in such a way that they are slipped over. In other embodiments, however, the caps can also be dimensioned so that they have almost the same diameter and the two ends of the caps come into contact or a certain distance remains between the cap ends after they have been put on, which distance is then bridged by the sealing film, for example.
  • FIGS. 2.1 and 2.2 show such a case of using differently dimensioned caps 52 , 54 with the machine also shown in FIG. 1.1-1.15 .
  • FIG. 2.1 corresponds to FIG. 1.8 and
  • FIG. 2.2 corresponds to FIG. 1.10 .
  • the first cap 52 has the same design, but the second cap 54 is designed to be shorter in length and has a diameter similar to the first.
  • FIGS. 2.1 and 2.2 It is also possible to use a somewhat longer second cap 54 , as in FIGS. 2.1 and 2.2 , so that the caps 52 , 54 are put on touching each other, i.e. they just meet or make contact when they are put on.
  • the intermediate region 100 is then a narrow gap or has an extent of almost zero.
  • first cap 52 and the upper end of the second cap 54 can be closed, latched and/or connected to one another during or after putting on the second cap 54 .
  • caps 52 , 54 In addition to complementary engagement elements 56 on the underside or upper side of the caps 52 , 54 , a choice of material is also possible, so that the caps 52 , 54 are already connected in the contact region by pressure and/or strands, preferably in a sterilely sealing manner.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Closing Of Containers (AREA)
US17/426,394 2019-01-28 2020-01-14 Method and device for sterilely enclosing a container Abandoned US20220097879A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102019201028.8A DE102019201028A1 (de) 2019-01-28 2019-01-28 Verfahren und Vorrichtung zum sterilen Umschließen eines Behälters
DE102019201028.8 2019-01-28
PCT/EP2020/050817 WO2020156803A1 (fr) 2019-01-28 2020-01-14 Procédé et dispositif de fermeture stérile d'un récipient

Publications (1)

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US20220097879A1 true US20220097879A1 (en) 2022-03-31

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US17/426,394 Abandoned US20220097879A1 (en) 2019-01-28 2020-01-14 Method and device for sterilely enclosing a container

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US (1) US20220097879A1 (fr)
EP (1) EP3917841A1 (fr)
CN (1) CN113272226B (fr)
DE (1) DE102019201028A1 (fr)
WO (1) WO2020156803A1 (fr)

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CN113272226B (zh) 2022-09-02
CN113272226A (zh) 2021-08-17
EP3917841A1 (fr) 2021-12-08
DE102019201028A1 (de) 2020-07-30
WO2020156803A1 (fr) 2020-08-06

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