US20110286573A1 - Method and apparatus for large field of view imaging and detection and compensation of motion artifacts - Google Patents

Method and apparatus for large field of view imaging and detection and compensation of motion artifacts Download PDF

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US20110286573A1
US20110286573A1 US13/145,128 US200913145128A US2011286573A1 US 20110286573 A1 US20110286573 A1 US 20110286573A1 US 200913145128 A US200913145128 A US 200913145128A US 2011286573 A1 US2011286573 A1 US 2011286573A1
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motion
projection data
detector
during
image
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Colas Schretter
Matthias Bertram
Christoph Neukirchen
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Koninklijke Philips NV
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Koninklijke Philips Electronics NV
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    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
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    • A61B6/52Devices using data or image processing specially adapted for radiation diagnosis
    • A61B6/5211Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data
    • A61B6/5217Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data extracting a diagnostic or physiological parameter from medical diagnostic data
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/54Control of apparatus or devices for radiation diagnosis
    • A61B6/542Control of apparatus or devices for radiation diagnosis involving control of exposure
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Definitions

  • a conventional CT imaging device includes an x-ray source and an x-ray sensitive detector disposed on opposite sides of an examination region.
  • a human patient or other object to be examined is supported in the examination region by a suitable support.
  • the source emits x-ray radiation which transverses the examination region and is detected by the detector as the source and detector rotate about a center of rotation.
  • a CT imaging device capable of having an offset geometry includes an x-ray source and an x-ray sensitive detector that may be transversely displaced from the center of rotation in the transaxial plane in certain configurations. Such offset geometry CT imaging devices are desirable because they allow for an increased field of view or allow for the use of a smaller sized detector.
  • the quality of images obtained from CT imaging devices is also frequently degraded by uncontrolled patient movement, such as the patient's failure to hold his or her breath, intestinal contractions, nervous shaking, natural cyclic motion, heartbeat, respiration, or other forms of motion.
  • iterative algorithmic motion compensation methods are used to improve image quality for images that contain motion artifacts. While such methods are capable of improving image quality for certain types of motion, the motion compensation effects accomplished by these methods are often inaccurate and they also can introduce artifacts into image regions that have not been affected by any motion.
  • a method and apparatus are provided for the detection and compensation of motion artifacts when reconstructing tomographic images.
  • a method and apparatus for creating a motion map is provided. The motion map is utilized to indicate which image regions may be corrupted by motion artifacts and/or for motion compensation to prevent motion artifacts in the reconstructed tomographic image.
  • the invention may take form in various components and arrangements of components, and in various process operations and arrangements of process operations.
  • FIG. 1 is a transaxial view of a centered CT acquisition geometry according to an embodiment of the invention
  • FIG. 2A is a transaxial view of a virtual detector which results from combining the data gathered from the centered geometry of FIG. 1 and the offset geometry of FIG. 2 ;
  • FIG. 3 is an imaging system according to an embodiment of the invention.
  • FIG. 4 depicts an imaging method according to an embodiment of the invention
  • FIG. 5 depicts a method for detecting motion according to an embodiment of the invention
  • FIGS. 6A and 6B depict optional methods for refining a motion map in accordance with an embodiment of the present invention
  • FIG. 7 is exemplary image generated by a software program depicting a motion map in accordance with an embodiment of the present invention.
  • FIG. 8 is an exemplary image generated by a software program depicting a motion-corrupted reconstructed image without any motion correction
  • FIG. 9 is an exemplary image generated by a software program depicting the reconstructed image of FIG. 8 after a global motion correction.
  • FIG. 10 is an exemplary image generated by a software program depicting the reconstructed image of FIG. 8 after a local motion correction.
  • One aspect of the present invention is directed generally to a method and apparatus for CT image acquisition, and more particularly to a method and apparatus for providing a large field of view (“FOV”) with improved image quality by utilizing at least two scanning procedures taken by a CT image apparatus. At least one scan is taken with the radiation source and detector of the CT image apparatus in a centered geometry and at least one scan is taken with the detector and/or source in an offset geometry. The image data obtained from the at least two scanning procedures is then combined to produce a reconstructed image.
  • FOV large field of view
  • FIG. 1 depicts an exemplary centered geometry 100 for a CT imaging apparatus.
  • the exemplary centered geometry 100 has an x-ray source 102 , such as an x-ray tube, and an x-ray sensitive detector 104 , such as a flat panel area detector array extending in the transverse and axial directions.
  • the center of rotation 114 may also serve as the center of the transverse field of view (FOV) 118 .
  • FOV transverse field of view
  • center of rotation 114 is not necessarily always aligned with the center of the transverse FOV 118 in every application.
  • an object support 110 supports the object 108 under examination in an examination region 106 .
  • a central ray or projection 116 of the x-ray beam 112 is perpendicular to the detector center 119 , which is aligned with the center of rotation 114 .
  • the x-ray source 102 and the x-ray sensitive detector 104 rotate about the center of rotation 114 .
  • the source 102 and detector 104 are generally mounted to a rotating gantry (not shown) for rotation about the examination region 106 . In some embodiments, however, the source 102 and detector 104 may remain at a constant angular position while the object 108 is moved and/or rotated to produce the requisite angular sampling. While the figures and description are focused on the use of flat panel detectors, arcuate detectors or detectors having yet other shapes may also be used. Furthermore, while the figures and discussion focus on a CT system in which the source 102 is a point source, other alternatives are contemplated. For example, the source 102 may be a line source. Gamma and other radiation sources may also be used. Multiple sources 102 and detectors 104 may also be provided, in which case corresponding sets of sources and detectors may be offset angularly and/or longitudinally from one another.
  • the x-ray source 102 and detector 104 of the exemplary centered geometry 100 are depicted in two opposing positions in the transaxial plane, position A in solid lines and position B in dotted lines.
  • position B the x-ray source 102 and detector 104 are rotated 180 degrees about the center of rotation 114 from position A.
  • the central ray 116 of the x-ray beam 112 and the detector center 119 are aligned with the center of rotation 114 when the x-ray source 102 and detector 104 are in both position A and position B.
  • FIG. 2 depicts an exemplary offset geometry 200 for an imaging apparatus.
  • the detector center 119 of the detector 104 of the exemplary offset geometry 200 is transversely displaced or offset from the center of rotation 114 in the transaxial plane by a distance D.
  • the x-ray source 102 and the x-ray sensitive detector 104 of the offset geometry 200 rotate about the center of rotation 114 .
  • the x-ray source 102 and detector 104 of the exemplary offset geometry 100 are depicted in two opposing positions in the transaxial plane, position A in solid lines and position B in dotted lines. In position B, the x-ray source 102 and detector 104 are rotated 180 degrees about the center of rotation 140 from position A.
  • the detector center 119 is offset from the center of rotation 114 in the transaxial plane by a distance D in both position A and position B.
  • the transverse FOV 218 of the offset geometry 200 is larger than the transverse FOV 118 of the centered geometry 100 .
  • the detector center 119 may be offset from the center of rotation 114 in the transaxial plane by various distances in different embodiments of the present invention by varying the distance D.
  • the detector center 114 may be offset from the center of rotation 119 by a distance D between 0 and 35 centimeters or greater.
  • the distance D may approximate, or even exceed, the transverse half-width of the detector, so that there is a “hole” 222 in the center of the transverse FOV 218 .
  • the distance D may be varied in multiple ways to customize the size of the transverse FOV 218 .
  • the detector 104 may be shifted to vary the size of the transverse FOV 118 by any suitable means.
  • the detector 104 may be moved in various directions relative to the rotating gantry and the center of rotation 114 either manually by a human user or by a mechanical drive. It can be shifted linearly, as is useful with a flat panel detector, or rotationally, as is useful for a curved detector.
  • the exemplary offset geometry 200 described includes a centered source and an offset detector, it should be understood that additional CT imaging device geometries, which include an offset source or an offset source and an offset detector are contemplated.
  • FIG. 2A depicts an overlay of the exemplary centered geometry 100 and the exemplary offset geometry 200 .
  • the x-ray source 102 and detector 104 of the exemplary centered geometry 100 and exemplary offset geometry 200 are overlaid each other in two opposing positions in the transaxial plane, position A in solid lines and position B in dotted lines.
  • the area of the detector 104 of the exemplary centered geometry 100 in position A that overlaps with the detector 104 of the exemplary offset geometry 200 in position A is indicated by the cross-hatched section 220 in FIG. 2A .
  • projection data obtained from the exemplary centered geometry 100 and exemplary offset geometry 200 can be combined together, as if they were measured by a single larger virtual detector V. This may be accomplished, for example, with faded weighting and/or averaging the projection data obtained in the overlapping region 220 .
  • projection data may not be obtained from a centered geometry and an offset geometry, but, rather, projection data may be obtained from two different offset geometries. For example, projection data could be obtained from a scan taken with the detector center 114 offset from the center of rotation 119 by a first distance D and a second set of projection data could be obtained from another scan taken with the detector center 114 offset from the center of rotation 199 by a second distance D.
  • FIG. 3 depicts a CT imaging system 300 suitable for use with the exemplary centered geometry 100 and offset geometry 200 described above.
  • the CT imaging system 300 includes a CT data acquisition system 302 , a reconstructor 304 , an image processor 306 , a user interface 308 , and a user input 310 .
  • the CT data acquisition system 302 includes the source 102 and detector 104 , which are mounted to a rotating gantry 312 for rotation about the examination region. Circular or other angular sampling ranges as well as axial, helical, circle and line, saddle, or other desired scanning trajectories are contemplated.
  • the embodiment of the CT imaging device system 300 illustrated in FIG. 3 includes a drive 318 , such as a microstep motor, that provides the requisite force required to move the source 102 and/or detector 104 .
  • the reconstructor 304 reconstructs the data generated by the data acquisition system 302 using reconstruction techniques to generate volumetric data indicative of the imaged subject.
  • Reconstruction techniques include analytical techniques such as filtered backprojection, as well as iterative techniques.
  • the image processor 306 processes the volumetric data as required, for example for display in a desired fashion on the user interface 308 , which may include one or more output devices such as a monitor and printer and one or more input devices such as a keyboard and mouse.
  • the user interface 308 which is advantageously implemented using software instructions executed by a general purpose or other computer so as to provide a graphical user interface (“GUI”), allows the user to control or otherwise interact with the imaging system 300 , for example by selecting a desired FOV configuration or dimension, initiating and/or terminating scans, selecting desired scan or reconstruction protocols, manipulating the volumetric data, and the like.
  • GUI graphical user interface
  • a user input 310 operatively connected to the user interface 308 controls the operation of the CT data acquisition system 302 , for example to carry out a desired scanning protocol, optionally position the detector 104 and/or the source 102 so as to provide the desired FOV, and the like.
  • FIG. 4 An exemplary imaging process 400 according to one aspect of the present invention is illustrated in FIG. 4 .
  • the CT imaging system 300 is utilized to take at least one scan of the imaged subject with the source 102 and detector 104 in the centered geometry 100 to acquire projection data at a sufficient plurality of angular positions about the examination region 106 .
  • at least one scan is taken by the CT imaging system 300 with the source 102 and detector 104 in an offset geometry 200 .
  • the order of steps 402 and 404 may be reversed, as the first scan(s) may be taken with the CT imaging system 300 in the offset geometry 200 followed by scan(s) with the CT imaging system 300 in the centered geometry 100 .
  • the detector 104 and/or the source 102 of the offset geometry 200 may be offset by a variety of distances D from the center of rotation 114 in the transaxial plane.
  • one or more scanning procedures may be conducted with the detector 104 and/or the source 102 offset from the center of rotation 114 in the transaxial plane by a different distance D in each scan.
  • centered geometry projection data 406 is obtained from the centered geometry scan(s) of step 402 and offset geometry projection data 408 is obtained from the offset geometry scan(s) of step 404 .
  • the reconstructor 304 reconstructs the centered geometry projection data 406 and offset geometry projection data 408 at step 410 using known reconstruction techniques currently used in connection with offset geometry CT imaging devices to generate volumetric data indicative of the imaged subject 108 , i.e., reconstructed image data 412 .
  • the centered geometry projection data 406 and the offset geometry projection data 408 are pair-wised stitched together using the overlapping region between the projection data 406 and 408 resulting from the overlapping region 220 of the detector 104 for the registration of the projection data 406 and 408 with each other. Faded weighting and/or averaging may be optionally applied in the overlap regions of the centered geometry projection data 406 and the offset geometry projection data 408 during the reconstruction process.
  • the combined reconstruction of the projection data 406 and 408 emulates a single scan with the large virtual detector V illustrated in FIG. 2A .
  • the image acquisition method disclosed herein involves the usage of at least two scanning operations provides certain freedom with the distribution of radiation dosage during the scanning procedures.
  • Different levels of radiation dosage may be associated with each of the scan(s) of step 404 and 402 as desired by the operator of the CT imaging device 300 .
  • the offset geometry scan(s) of step 404 may be adapted to deliver less than half of the radiation dosage that is used in connection with the centered geometry scan(s) of step 402 .
  • dosage techniques can result in a better contrast-to-noise ratio being obtained for the centered geometry scan(s) of step 402 .
  • the border areas of the imaged subject scanned by the offset geometry scan(s) of step 404 which are less relevant for medical diagnosis but useful for attenuation correction, will be exposed to relatively less radiation.
  • the radiation dosage delivered to a patient during the scanning procedures of steps 402 and 404 can be tailored to be generally equivalent or less than the radiation dosage delivered to a patient during a single scan with a wide detector, such as those used in helical CT imaging.
  • Another aspect of the present invention is directed generally to a method and apparatus for the detection, estimation and/or compensation of motion artifacts encountered when reconstructing tomographic images.
  • a method and apparatus are provided for generating a motion map.
  • the motion map is utilized to indicate which image regions may be corrupted by motion artifacts and/or for motion estimation and motion compensation to prevent or diminish motion artifacts in the reconstructed tomographic image.
  • FIG. 5 An exemplary method 500 of detecting motion in reconstructed tomographic images according to one aspect of the present invention is illustrated in FIG. 5 .
  • the CT imaging system 300 is used to obtain a set of acquired projection data 504 of the imaged subject 108 .
  • tomographic reconstruction is applied to this acquired projection data 504 using known reconstruction techniques, such as filtered backprojection (FBP), to generate a reconstructed image (i.e., the “reference” image) 508 .
  • the reference image 508 may have artifacts as a result of object movement during the scanning process.
  • known forward projection techniques are applied to the previously reconstructed reference image 508 to derive reference projection data 512 .
  • reference projection data by the forward projection of a reconstructed image is a conventional aspect of iterative image reconstruction, it should be understood by those skilled in the art that the accuracy of image space interpolations and the possible truncation of projections are two important potential issues that may need to be addressed during this process. Furthermore, if the reference image 508 is reconstructed using the classical Feldkamp-Davis-Kress (FDK) algorithm, cone beam artifacts may corrupt the reference projections and hence should be accounted for.
  • FDK Feldkamp-Davis-Kress
  • the line integral differences 516 between the acquired projection data 504 and the reference projection data 512 are computed. Any such differences likely result from artifacts caused by movement of the object during the imaging scan 502 .
  • the line integral differences 516 between the acquired projection data 504 and the reference projection data 512 are computed independently for each pair of corresponding projections from the acquired projection data 504 and reference projection data 512 .
  • a data correction step could be optionally employed at this stage using, for example, the Helgason-Ludwig conditions or other similar data correction measures to correct any data inconsistencies.
  • the line integral differences 516 represent an isolation of motion that occurred during the scanning procedure 502 in projection space.
  • FIG. 6A An optional exemplary method 600 for refining the motion map 520 in accordance with an embodiment of the present invention is illustrated in FIG. 6A .
  • the line integral differences 516 may be processed or refined, such as for example by windowing, normalization, or filtering, to produce pre-processed line integral differences 604 .
  • a windowing refinement is a non-linear mapping of input values to modified output values, where input values below a given minimum value and above a given maximum value are ignored or set to zero.
  • thresholding may be applied, where input values below a given threshold are set to zero and values above the threshold are set to one.
  • Another sort of refinement is normalization, wherein the line integral differences are transformed to values between 0 and 1 to standardize and simplify subsequent mathematical calculations.
  • Yet another sort of refinement is to apply a volumetric median filter, a Gaussian blur, or some other filtering process.
  • the size of the neighborhood for the volumetric median filter and the size of the convolution kernel for the Gaussian blur are set to 3 ⁇ 3 ⁇ 3.
  • the pre-processing refinement 602 may also involve other kinds of image processing in additional embodiments.
  • the pre-processed line integral differences 604 are reconstructed using known reconstruction techniques, such as filtered backprojection (FBP), at step 606 .
  • the resulting image that is generated is a refined motion map 608 , that has been windowed, normalized, filtered, or otherwise refined.
  • the refined motion map 608 could be adapted to be either a binary motion map that simply indicates whether or not motion exists in a given image voxel or the refined motion map 608 could indicate the amplitude of the motion that exists in any given image voxel.
  • FIG. 6B Another optional exemplary method 610 for refining the motion map 520 in accordance with an embodiment of the present invention is illustrated in FIG. 6B .
  • the line integral differences 516 are reconstructed using known reconstruction techniques, such as filtered backprojection (FBP).
  • FBP filtered backprojection
  • the resulting image that is generated is an initial motion map 614 .
  • the initial motion map 614 is then processed or refined at step 616 , such as for example by windowing, normalization, filtering, to produce a post-processed refined motion map 618 .
  • the initial motion map 614 is thresholded at 150 Hounsfield units (HU).
  • Such processing or refining of the motion map 614 serves to remove “reconstruction noise” or other inconsistencies in the data and to avoid streaking
  • a motion map such as the motion map 520 , 608 or 618 has multiple uses.
  • the motion map can be used as a reference by a radiologist or other individual performing the imaging process to indicate which voxels of a particular reconstructed image could potentially contain reconstruction artifacts due to motion, e.g., regions of an image with potential motion artifacts that cause them to be unsuitable for diagnosis or localization.
  • the motion map serves as a reliability indicator to be used in conjunction with a reconstructed image, as it supplies information about the location of in-scan motion present in the reconstructed image.
  • the motion map can be combined with a motion estimation and compensation scheme to apply local motion correction during image reconstruction.
  • Conventional global motion compensation techniques are applied universally to the entire image during the reconstruction process. This can result in artifacts being introduced into regions of the reconstructed image which were not affected by any motion. As a result, in practice, these global motion compensation methods can corrupt static regions of reconstructed images with artifacts resulting from incorrect motion compensation.
  • the use of the motion map in conjunction with local motion correction prevents the application of motion compensation in static regions where no motion occurred during the scanning procedure. This can prevent artifacts in such static regions.
  • the motion map could be used as a “blending map” with motion correction techniques being applied only in those areas which are indicated to have experienced motion based upon the motion map.
  • the motion map could also be used as a “weighting map.” Under this approach, the motion map would be used to determine a “weighted” amount of motion correction that would be applied to any given image voxel, which would be an adjusted value between zero motion correction being applied and, at most, the amount of motion correction that would be applied under current conventional global motion correction techniques.
  • FIG. 8 an exemplary motion-corrupted image generated by a software program is illustrated in FIG. 8 .
  • FIG. 9 is a reconstruction of the image in FIG. 8 that has undergone global motion correction.
  • FIG. 10 is a reconstruction of the image in FIG. 8 that has undergone local motion correction using a motion map.
  • Logic includes but is not limited to hardware, firmware, software and/or combinations of each to perform a function(s) or an action(s), and/or to cause a function or action from another component.
  • logic may include a software controlled microprocessor, discrete logic such as an application specific integrated circuit (ASIC), or other programmed logic device.
  • ASIC application specific integrated circuit
  • Software includes but is not limited to one or more computer readable and/or executable instructions that cause a computer or other electronic device to perform functions, actions, and/or behave in a desired manner.
  • the instructions may be embodied in various forms such as routines, algorithms, modules or programs including separate applications or code from dynamically linked libraries.
  • Software may also be implemented in various forms such as a stand-alone program, a function call, a servlet, an applet, instructions stored in a memory, part of an operating system or other type of executable instructions. It will be appreciated by one of ordinary skill in the art that the form of software is dependent on, for example, requirements of a desired application, the environment it runs on, and/or the desires of a designer/programmer or the like.
  • the systems and methods described herein can be implemented on a variety of platforms including, for example, networked control systems and stand-alone control systems. Additionally, the logic, databases or tables shown and described herein preferably reside in or on a computer readable medium, such as a component of the imaging system 300 . Examples of different computer readable media include Flash Memory, Read-Only Memory (ROM), Random-Access Memory (RAM), programmable read-only memory (PROM), electrically programmable read-only memory (EPROM), electrically erasable programmable read-only memory (EEPROM), magnetic disk or tape, optically readable mediums including CD-ROM and DVD-ROM, and others. Still further, the processes and logic described herein can be merged into one large process flow or divided into many sub-process flows. The order in which the process flows herein have been described is not critical and can be rearranged while still accomplishing the same results. Indeed, the process flows described herein may be rearranged, consolidated, and/or re-organized in their implementation as warranted or desired.

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  • Apparatus For Radiation Diagnosis (AREA)

Abstract

A method and apparatus are provided to improve large field of view CT image acquisition by using at least two scanning procedures: (i) one with the radiation source and detector centered and (ii) one in an offset configuration. The imaging data obtained from both of the scanning procedures is used in the reconstruction of the image. In addition, a method and apparatus are provided for detecting motion in a reconstructed image by generating a motion map that is indicative of the regions of the reconstructed image that are affected by motion artifacts. Optionally, the motion map may be used for motion estimation and/or motion compensation to prevent or diminish motion artifacts in the resulting reconstructed image. An optional method for generating a refined motion map is also provided.

Description

  • The present application relates generally to the imaging arts. In one embodiment, it provides a method and apparatus for imaging large objects. In another embodiment, it provides for the detection and compensation of motion artifacts when reconstructing tomographic images. The application subject matter finds use at least with computed tomography (CT) imaging, and more particularly with flat detector cone-beam computed tomography (CBCT) imaging, and will be described with particular reference thereto. However, it also has more general application with other imaging methods and in other arts.
  • A conventional CT imaging device includes an x-ray source and an x-ray sensitive detector disposed on opposite sides of an examination region. A human patient or other object to be examined is supported in the examination region by a suitable support. The source emits x-ray radiation which transverses the examination region and is detected by the detector as the source and detector rotate about a center of rotation. A CT imaging device capable of having an offset geometry includes an x-ray source and an x-ray sensitive detector that may be transversely displaced from the center of rotation in the transaxial plane in certain configurations. Such offset geometry CT imaging devices are desirable because they allow for an increased field of view or allow for the use of a smaller sized detector.
  • However, existing offset geometry CT imaging devices may not adequately accommodate certain large objects, such as an obese patient. In part that is because x-ray source and detector offsets may deteriorate the quality of the reconstructed image. Furthermore, attenuation correction during reconstruction benefits from full anatomical coverage, which may not be possible even with large offsets.
  • Furthermore, the quality of images obtained from CT imaging devices, especially slowly rotating CBCT imaging devices, is also frequently degraded by uncontrolled patient movement, such as the patient's failure to hold his or her breath, intestinal contractions, nervous shaking, natural cyclic motion, heartbeat, respiration, or other forms of motion. Currently, iterative algorithmic motion compensation methods are used to improve image quality for images that contain motion artifacts. While such methods are capable of improving image quality for certain types of motion, the motion compensation effects accomplished by these methods are often inaccurate and they also can introduce artifacts into image regions that have not been affected by any motion.
  • It is desirable to provide a method and apparatus that permit a larger field of view than current CT imaging devices with offset geometries and that alleviate the artifacts that typically occur in reconstructed images obtained from existing CT imaging devices with large offset geometries. Further, it is also desirable to provide a method and apparatus for detecting image regions that are affected by motion artifacts when reconstructing tomographic images and for providing motion estimation and motion compensation to prevent such motion artifacts in the resulting reconstructed image.
  • Aspects of the present invention address these matters, and others.
  • According to one aspect of the present invention, a method and apparatus are provided to improve large field of view CT image acquisition using two scanning procedures: (i) one with the radiation source and detector centered and (ii) one with the detector being offset. In accordance with this aspect, a large field of view can be achieved that can accommodate larger objects than can currently be accommodated by existing CT imaging devices with offset geometries. In addition, as the imaging data from both of the scanning procedures is used in the reconstruction of the image, the artifacts that typically occur with reconstruction of imaging data obtained from existing CT imaging devices with large offset geometries can be avoided because of the large overlap between virtual detectors in opposite viewing directions.
  • According to another aspect of the present invention, a method and apparatus are provided for the detection and compensation of motion artifacts when reconstructing tomographic images. In accordance with this aspect, a method and apparatus for creating a motion map is provided. The motion map is utilized to indicate which image regions may be corrupted by motion artifacts and/or for motion compensation to prevent motion artifacts in the reconstructed tomographic image.
  • Still further aspects of the present invention will be appreciated by those of ordinary skill in the art upon reading and understanding the following detailed description. Numerous additional advantages and benefits will become apparent to those of ordinary skill in the art upon reading the following detailed description of preferred embodiments.
  • The invention may take form in various components and arrangements of components, and in various process operations and arrangements of process operations.
  • The drawings are only for the purpose of illustrating preferred embodiments and are not to be construed as limiting the invention.
  • FIG. 1 is a transaxial view of a centered CT acquisition geometry according to an embodiment of the invention;
  • FIG. 2 is a transaxial view of an offset CT acquisition geometry according to an embodiment of the invention;
  • FIG. 2A is a transaxial view of a virtual detector which results from combining the data gathered from the centered geometry of FIG. 1 and the offset geometry of FIG. 2;
  • FIG. 3 is an imaging system according to an embodiment of the invention; and
  • FIG. 4 depicts an imaging method according to an embodiment of the invention;
  • FIG. 5 depicts a method for detecting motion according to an embodiment of the invention;
  • FIGS. 6A and 6B depict optional methods for refining a motion map in accordance with an embodiment of the present invention;
  • FIG. 7 is exemplary image generated by a software program depicting a motion map in accordance with an embodiment of the present invention;
  • FIG. 8 is an exemplary image generated by a software program depicting a motion-corrupted reconstructed image without any motion correction;
  • FIG. 9 is an exemplary image generated by a software program depicting the reconstructed image of FIG. 8 after a global motion correction; and
  • FIG. 10 is an exemplary image generated by a software program depicting the reconstructed image of FIG. 8 after a local motion correction.
  • One aspect of the present invention is directed generally to a method and apparatus for CT image acquisition, and more particularly to a method and apparatus for providing a large field of view (“FOV”) with improved image quality by utilizing at least two scanning procedures taken by a CT image apparatus. At least one scan is taken with the radiation source and detector of the CT image apparatus in a centered geometry and at least one scan is taken with the detector and/or source in an offset geometry. The image data obtained from the at least two scanning procedures is then combined to produce a reconstructed image.
  • FIG. 1 depicts an exemplary centered geometry 100 for a CT imaging apparatus. The exemplary centered geometry 100 has an x-ray source 102, such as an x-ray tube, and an x-ray sensitive detector 104, such as a flat panel area detector array extending in the transverse and axial directions. As illustrated in FIG. 1, the center of rotation 114 may also serve as the center of the transverse field of view (FOV) 118.
  • However, the center of rotation 114 is not necessarily always aligned with the center of the transverse FOV 118 in every application. As illustrated, an object support 110 supports the object 108 under examination in an examination region 106. A central ray or projection 116 of the x-ray beam 112 is perpendicular to the detector center 119, which is aligned with the center of rotation 114.
  • The x-ray source 102 and the x-ray sensitive detector 104 rotate about the center of rotation 114. The source 102 and detector 104 are generally mounted to a rotating gantry (not shown) for rotation about the examination region 106. In some embodiments, however, the source 102 and detector 104 may remain at a constant angular position while the object 108 is moved and/or rotated to produce the requisite angular sampling. While the figures and description are focused on the use of flat panel detectors, arcuate detectors or detectors having yet other shapes may also be used. Furthermore, while the figures and discussion focus on a CT system in which the source 102 is a point source, other alternatives are contemplated. For example, the source 102 may be a line source. Gamma and other radiation sources may also be used. Multiple sources 102 and detectors 104 may also be provided, in which case corresponding sets of sources and detectors may be offset angularly and/or longitudinally from one another.
  • In FIG. 1, the x-ray source 102 and detector 104 of the exemplary centered geometry 100 are depicted in two opposing positions in the transaxial plane, position A in solid lines and position B in dotted lines. In position B, the x-ray source 102 and detector 104 are rotated 180 degrees about the center of rotation 114 from position A. As both the x-ray source 102 and detector 104 of the exemplary centered geometry 100 are centered with respect to the center of rotation 114, the central ray 116 of the x-ray beam 112 and the detector center 119 are aligned with the center of rotation 114 when the x-ray source 102 and detector 104 are in both position A and position B.
  • FIG. 2 depicts an exemplary offset geometry 200 for an imaging apparatus. The detector center 119 of the detector 104 of the exemplary offset geometry 200 is transversely displaced or offset from the center of rotation 114 in the transaxial plane by a distance D. As described previously in connection with the centered geometry 100, the x-ray source 102 and the x-ray sensitive detector 104 of the offset geometry 200 rotate about the center of rotation 114. In FIG. 2, the x-ray source 102 and detector 104 of the exemplary offset geometry 100 are depicted in two opposing positions in the transaxial plane, position A in solid lines and position B in dotted lines. In position B, the x-ray source 102 and detector 104 are rotated 180 degrees about the center of rotation 140 from position A. As illustrated in FIG. 2, the detector center 119 is offset from the center of rotation 114 in the transaxial plane by a distance D in both position A and position B.
  • The transverse FOV 218 of the offset geometry 200 is larger than the transverse FOV 118 of the centered geometry 100. The detector center 119 may be offset from the center of rotation 114 in the transaxial plane by various distances in different embodiments of the present invention by varying the distance D. For example, the detector center 114 may be offset from the center of rotation 119 by a distance D between 0 and 35 centimeters or greater. The distance D may approximate, or even exceed, the transverse half-width of the detector, so that there is a “hole” 222 in the center of the transverse FOV 218. The distance D may be varied in multiple ways to customize the size of the transverse FOV 218. The detector 104 may be shifted to vary the size of the transverse FOV 118 by any suitable means. For example, the detector 104 may be moved in various directions relative to the rotating gantry and the center of rotation 114 either manually by a human user or by a mechanical drive. It can be shifted linearly, as is useful with a flat panel detector, or rotationally, as is useful for a curved detector. While the exemplary offset geometry 200 described includes a centered source and an offset detector, it should be understood that additional CT imaging device geometries, which include an offset source or an offset source and an offset detector are contemplated.
  • FIG. 2A depicts an overlay of the exemplary centered geometry 100 and the exemplary offset geometry 200. In FIG. 2A, the x-ray source 102 and detector 104 of the exemplary centered geometry 100 and exemplary offset geometry 200 are overlaid each other in two opposing positions in the transaxial plane, position A in solid lines and position B in dotted lines. The area of the detector 104 of the exemplary centered geometry 100 in position A that overlaps with the detector 104 of the exemplary offset geometry 200 in position A is indicated by the cross-hatched section 220 in FIG. 2A. Likewise, there is also an overlapping region 220 between the detector 104 of the exemplary centered geometry 100 in position B and the detector 104 of the exemplary offset geometry 200 in position B. During image reconstruction, the projection data obtained from the exemplary centered geometry 100 and exemplary offset geometry 200 can be combined together, as if they were measured by a single larger virtual detector V. This may be accomplished, for example, with faded weighting and/or averaging the projection data obtained in the overlapping region 220. In additional embodiments, projection data may not be obtained from a centered geometry and an offset geometry, but, rather, projection data may be obtained from two different offset geometries. For example, projection data could be obtained from a scan taken with the detector center 114 offset from the center of rotation 119 by a first distance D and a second set of projection data could be obtained from another scan taken with the detector center 114 offset from the center of rotation 199 by a second distance D.
  • FIG. 3 depicts a CT imaging system 300 suitable for use with the exemplary centered geometry 100 and offset geometry 200 described above. The CT imaging system 300 includes a CT data acquisition system 302, a reconstructor 304, an image processor 306, a user interface 308, and a user input 310. The CT data acquisition system 302 includes the source 102 and detector 104, which are mounted to a rotating gantry 312 for rotation about the examination region. Circular or other angular sampling ranges as well as axial, helical, circle and line, saddle, or other desired scanning trajectories are contemplated. The embodiment of the CT imaging device system 300 illustrated in FIG. 3 includes a drive 318, such as a microstep motor, that provides the requisite force required to move the source 102 and/or detector 104.
  • The reconstructor 304 reconstructs the data generated by the data acquisition system 302 using reconstruction techniques to generate volumetric data indicative of the imaged subject. Reconstruction techniques include analytical techniques such as filtered backprojection, as well as iterative techniques. The image processor 306 processes the volumetric data as required, for example for display in a desired fashion on the user interface 308, which may include one or more output devices such as a monitor and printer and one or more input devices such as a keyboard and mouse.
  • The user interface 308, which is advantageously implemented using software instructions executed by a general purpose or other computer so as to provide a graphical user interface (“GUI”), allows the user to control or otherwise interact with the imaging system 300, for example by selecting a desired FOV configuration or dimension, initiating and/or terminating scans, selecting desired scan or reconstruction protocols, manipulating the volumetric data, and the like.
  • A user input 310 operatively connected to the user interface 308 controls the operation of the CT data acquisition system 302, for example to carry out a desired scanning protocol, optionally position the detector 104 and/or the source 102 so as to provide the desired FOV, and the like.
  • An exemplary imaging process 400 according to one aspect of the present invention is illustrated in FIG. 4. In step 402, the CT imaging system 300 is utilized to take at least one scan of the imaged subject with the source 102 and detector 104 in the centered geometry 100 to acquire projection data at a sufficient plurality of angular positions about the examination region 106. In step 404, at least one scan is taken by the CT imaging system 300 with the source 102 and detector 104 in an offset geometry 200. The order of steps 402 and 404 may be reversed, as the first scan(s) may be taken with the CT imaging system 300 in the offset geometry 200 followed by scan(s) with the CT imaging system 300 in the centered geometry 100. As discussed above, the detector 104 and/or the source 102 of the offset geometry 200 may be offset by a variety of distances D from the center of rotation 114 in the transaxial plane. In additional embodiments, one or more scanning procedures may be conducted with the detector 104 and/or the source 102 offset from the center of rotation 114 in the transaxial plane by a different distance D in each scan.
  • As shown in FIG. 4, centered geometry projection data 406 is obtained from the centered geometry scan(s) of step 402 and offset geometry projection data 408 is obtained from the offset geometry scan(s) of step 404. The reconstructor 304 reconstructs the centered geometry projection data 406 and offset geometry projection data 408 at step 410 using known reconstruction techniques currently used in connection with offset geometry CT imaging devices to generate volumetric data indicative of the imaged subject 108, i.e., reconstructed image data 412. During reconstruction, the centered geometry projection data 406 and the offset geometry projection data 408 are pair-wised stitched together using the overlapping region between the projection data 406 and 408 resulting from the overlapping region 220 of the detector 104 for the registration of the projection data 406 and 408 with each other. Faded weighting and/or averaging may be optionally applied in the overlap regions of the centered geometry projection data 406 and the offset geometry projection data 408 during the reconstruction process. The combined reconstruction of the projection data 406 and 408 emulates a single scan with the large virtual detector V illustrated in FIG. 2A.
  • The reconstructed image data 412 obtained from step 410 is processed by the image processor 306. The resulting reconstructed image is displayed on the user interface 308 at step 414.
  • Existing CT imaging devices with offset geometries often suffer from image quality problems due to a limited data redundancy between opposite viewing directions, especially if the detector offset is large. Insufficient redundancies can visibly degrade image quality during reconstruction. These image degrading effects encountered with existing CT imaging devices utilizing offset geometries are largely avoided with the apparatus and method disclosed herein, because an even larger field of view can be achieved while significant redundancy between opposite virtual enlarged views is nevertheless guaranteed. Specifically, an “overlap” between opposite virtual enlarged views of half the actual detector width can easily be achieved, minimizing the likelihood and effect of artifacts occurring as a result of approximations made in the reconstruction for an off-center geometry.
  • The fact that the image acquisition method disclosed herein involves the usage of at least two scanning operations provides certain freedom with the distribution of radiation dosage during the scanning procedures. Different levels of radiation dosage may be associated with each of the scan(s) of step 404 and 402 as desired by the operator of the CT imaging device 300. For example, the offset geometry scan(s) of step 404 may be adapted to deliver less than half of the radiation dosage that is used in connection with the centered geometry scan(s) of step 402. Such dosage techniques can result in a better contrast-to-noise ratio being obtained for the centered geometry scan(s) of step 402. At the same time, the border areas of the imaged subject scanned by the offset geometry scan(s) of step 404, which are less relevant for medical diagnosis but useful for attenuation correction, will be exposed to relatively less radiation. In this manner, the radiation dosage delivered to a patient during the scanning procedures of steps 402 and 404 can be tailored to be generally equivalent or less than the radiation dosage delivered to a patient during a single scan with a wide detector, such as those used in helical CT imaging.
  • Another aspect of the present invention is directed generally to a method and apparatus for the detection, estimation and/or compensation of motion artifacts encountered when reconstructing tomographic images. In accordance with this aspect, a method and apparatus are provided for generating a motion map. The motion map is utilized to indicate which image regions may be corrupted by motion artifacts and/or for motion estimation and motion compensation to prevent or diminish motion artifacts in the reconstructed tomographic image.
  • An exemplary method 500 of detecting motion in reconstructed tomographic images according to one aspect of the present invention is illustrated in FIG. 5. At step 502, the CT imaging system 300 is used to obtain a set of acquired projection data 504 of the imaged subject 108. At step 506, tomographic reconstruction is applied to this acquired projection data 504 using known reconstruction techniques, such as filtered backprojection (FBP), to generate a reconstructed image (i.e., the “reference” image) 508. The reference image 508 may have artifacts as a result of object movement during the scanning process. At step 510, known forward projection techniques are applied to the previously reconstructed reference image 508 to derive reference projection data 512. Although the computation of reference projection data by the forward projection of a reconstructed image is a conventional aspect of iterative image reconstruction, it should be understood by those skilled in the art that the accuracy of image space interpolations and the possible truncation of projections are two important potential issues that may need to be addressed during this process. Furthermore, if the reference image 508 is reconstructed using the classical Feldkamp-Davis-Kress (FDK) algorithm, cone beam artifacts may corrupt the reference projections and hence should be accounted for.
  • Next, at step 514, the line integral differences 516 between the acquired projection data 504 and the reference projection data 512 are computed. Any such differences likely result from artifacts caused by movement of the object during the imaging scan 502. The line integral differences 516 between the acquired projection data 504 and the reference projection data 512 are computed independently for each pair of corresponding projections from the acquired projection data 504 and reference projection data 512. A data correction step could be optionally employed at this stage using, for example, the Helgason-Ludwig conditions or other similar data correction measures to correct any data inconsistencies. The line integral differences 516 represent an isolation of motion that occurred during the scanning procedure 502 in projection space.
  • At step 518, tomographic reconstruction is applied to the absolute values of the line integral differences 516 using known reconstruction techniques, such as filtered backprojection (FBP). The resulting image that is generated is a motion map 520, which is representative of the regions of the image 508 which are corrupted by motion that occurred during the scanning procedure 502. Thus the motion map 520 represents an isolation of the motion that occurred during the scanning procedure 502 in image space. The motion map 520 could be adapted to be a binary motion map that simply indicates whether or not motion exists in a given image voxel. Alternatively, a refined motion map 520 could indicate the amplitude of the motion that exists in any given image voxel. An exemplary motion map 520 is illustrated in FIG. 7. It should be understood by those skilled in the art that the exemplary method 500 of generating a motion map 520 may be an iterative process in additional embodiments.
  • An optional exemplary method 600 for refining the motion map 520 in accordance with an embodiment of the present invention is illustrated in FIG. 6A. At step 602, the line integral differences 516 may be processed or refined, such as for example by windowing, normalization, or filtering, to produce pre-processed line integral differences 604. A windowing refinement is a non-linear mapping of input values to modified output values, where input values below a given minimum value and above a given maximum value are ignored or set to zero. As a special form of windowing, thresholding may be applied, where input values below a given threshold are set to zero and values above the threshold are set to one. Another sort of refinement is normalization, wherein the line integral differences are transformed to values between 0 and 1 to standardize and simplify subsequent mathematical calculations. Yet another sort of refinement is to apply a volumetric median filter, a Gaussian blur, or some other filtering process. In one exemplary embodiment, the size of the neighborhood for the volumetric median filter and the size of the convolution kernel for the Gaussian blur are set to 3×3×3. The pre-processing refinement 602 may also involve other kinds of image processing in additional embodiments.
  • The pre-processed line integral differences 604 are reconstructed using known reconstruction techniques, such as filtered backprojection (FBP), at step 606. The resulting image that is generated is a refined motion map 608, that has been windowed, normalized, filtered, or otherwise refined. The refined motion map 608 could be adapted to be either a binary motion map that simply indicates whether or not motion exists in a given image voxel or the refined motion map 608 could indicate the amplitude of the motion that exists in any given image voxel.
  • Another optional exemplary method 610 for refining the motion map 520 in accordance with an embodiment of the present invention is illustrated in FIG. 6B. At step 612, the line integral differences 516 are reconstructed using known reconstruction techniques, such as filtered backprojection (FBP). The resulting image that is generated is an initial motion map 614. The initial motion map 614 is then processed or refined at step 616, such as for example by windowing, normalization, filtering, to produce a post-processed refined motion map 618. For example, in one exemplary embodiment the initial motion map 614 is thresholded at 150 Hounsfield units (HU). Such processing or refining of the motion map 614 serves to remove “reconstruction noise” or other inconsistencies in the data and to avoid streaking
  • A motion map such as the motion map 520, 608 or 618 has multiple uses. For example, the motion map can be used as a reference by a radiologist or other individual performing the imaging process to indicate which voxels of a particular reconstructed image could potentially contain reconstruction artifacts due to motion, e.g., regions of an image with potential motion artifacts that cause them to be unsuitable for diagnosis or localization. In this manner, the motion map serves as a reliability indicator to be used in conjunction with a reconstructed image, as it supplies information about the location of in-scan motion present in the reconstructed image.
  • In addition, the motion map can be combined with a motion estimation and compensation scheme to apply local motion correction during image reconstruction. Conventional global motion compensation techniques are applied universally to the entire image during the reconstruction process. This can result in artifacts being introduced into regions of the reconstructed image which were not affected by any motion. As a result, in practice, these global motion compensation methods can corrupt static regions of reconstructed images with artifacts resulting from incorrect motion compensation.
  • However, the use of the motion map in conjunction with local motion correction prevents the application of motion compensation in static regions where no motion occurred during the scanning procedure. This can prevent artifacts in such static regions. For example, the motion map could be used as a “blending map” with motion correction techniques being applied only in those areas which are indicated to have experienced motion based upon the motion map. Furthermore, the motion map could also be used as a “weighting map.” Under this approach, the motion map would be used to determine a “weighted” amount of motion correction that would be applied to any given image voxel, which would be an adjusted value between zero motion correction being applied and, at most, the amount of motion correction that would be applied under current conventional global motion correction techniques. Still further uses and applications of the motion map will be appreciated by those of ordinary skill in the art. To further illustrate the application of the motion compensation techniques described herein, an exemplary motion-corrupted image generated by a software program is illustrated in FIG. 8. FIG. 9 is a reconstruction of the image in FIG. 8 that has undergone global motion correction. FIG. 10 is a reconstruction of the image in FIG. 8 that has undergone local motion correction using a motion map.
  • The aforementioned functions, such as for example, selecting a desired FOV configuration or dimension, initiating and/or terminating scans, selecting desired scan or reconstruction protocols, manipulating the volumetric data, and the like, can be performed as software logic. “Logic,” as used herein, includes but is not limited to hardware, firmware, software and/or combinations of each to perform a function(s) or an action(s), and/or to cause a function or action from another component. For example, based on a desired application or needs, logic may include a software controlled microprocessor, discrete logic such as an application specific integrated circuit (ASIC), or other programmed logic device. Logic may also be fully embodied as software.
  • “Software,” as used herein, includes but is not limited to one or more computer readable and/or executable instructions that cause a computer or other electronic device to perform functions, actions, and/or behave in a desired manner. The instructions may be embodied in various forms such as routines, algorithms, modules or programs including separate applications or code from dynamically linked libraries. Software may also be implemented in various forms such as a stand-alone program, a function call, a servlet, an applet, instructions stored in a memory, part of an operating system or other type of executable instructions. It will be appreciated by one of ordinary skill in the art that the form of software is dependent on, for example, requirements of a desired application, the environment it runs on, and/or the desires of a designer/programmer or the like.
  • The systems and methods described herein can be implemented on a variety of platforms including, for example, networked control systems and stand-alone control systems. Additionally, the logic, databases or tables shown and described herein preferably reside in or on a computer readable medium, such as a component of the imaging system 300. Examples of different computer readable media include Flash Memory, Read-Only Memory (ROM), Random-Access Memory (RAM), programmable read-only memory (PROM), electrically programmable read-only memory (EPROM), electrically erasable programmable read-only memory (EEPROM), magnetic disk or tape, optically readable mediums including CD-ROM and DVD-ROM, and others. Still further, the processes and logic described herein can be merged into one large process flow or divided into many sub-process flows. The order in which the process flows herein have been described is not critical and can be rearranged while still accomplishing the same results. Indeed, the process flows described herein may be rearranged, consolidated, and/or re-organized in their implementation as warranted or desired.
  • The invention has been described with reference to the preferred embodiments. Modifications and alterations may occur to others upon reading and understanding the preceding detailed description. It is intended that the invention be constructed as including all such modifications and alterations insofar as they come within the scope of the appended claims or the equivalents thereof.

Claims (37)

1. An apparatus for acquiring tomographic projection data at a plurality of angular positions relative to an object disposed in an examination region, the apparatus comprising:
a radiation source;
a radiation sensitive detector which detects radiation emitted by the source that has traversed the examination region; and
a reconstructor;
wherein the apparatus is adapted to perform at least two scanning procedures of an object;
wherein at least a first scanning procedure is a centered geometry scanning procedure, wherein a center of the radiation sensitive detector is aligned with a center of rotation of the source and detector;
wherein at least a second scanning procedure is an offset geometry scanning procedure; wherein a center of the radiation sensitive detector is displaced by a distance of approximately half a width of the detector or more from the center of rotation of the source and detector;
wherein projection data is acquired during the at least two scanning procedures including centered geometry projection data during the centered geometry scanning procedure and offset geometry projection data during the offset geometry scanning procedure; and
wherein the reconstructor reconstructs the projection data acquired during the at least two scanning procedures together to generate volumetric data indicative of the object.
2. (canceled)
3. The apparatus of claim 1, wherein the reconstruction performed by the reconstructor combines the projection data acquired during the at least two scanning procedures to form a data set corresponding to an imaging scan performed by a single virtual detector in one position with respect to the source.
4. The apparatus of claim 1, wherein the radiation sensitive detector is a flat detector, and wherein the center of the radiation sensitive detector is transversely displaced from the center of rotation in the transaxial plane during the at least one offset geometry scanning procedure.
5. (canceled)
6. The apparatus of claim 1, wherein a faded weighting technique and an averaging technique are applied to an overlap region of the projection data acquired during the at least two scanning procedures during reconstruction.
7. The apparatus of claim 1, wherein a lower dose of radiation is administered during the at least one offset geometry scanning procedure than during the at least one centered geometry scanning procedure.
8. The apparatus of claim 7, wherein the dose of radiation administered during the at least one offset geometry scanning procedure is less than half of the radiation administered during the at least one centered geometry scanning procedure.
9. The apparatus of claim 1, wherein the apparatus is a cone-beam computed tomography imaging device.
10. The apparatus of claim 1, further comprising a mechanical drive for moving the radiation sensitive detector with respect to the radiation source.
11. The apparatus of claim 1, further comprising an image processor, a user interface and a user input, and wherein the image processor processes the volumetric data for display on the user interface.
12. A computed tomography imaging method, comprising the steps of:
performing at least two scanning procedures of an object, including:
acquiring projection data during at least one centered geometry scanning procedure in which a center of the radiation sensitive detector is aligned with a center of rotation of the source and detector; and
acquiring projection data during at least one offset geometry scanning procedure in which a center of the radiation sensitive detector is displaced from the center of rotation of the source and detector by a distance of approximately half a width of the detector or more;
acquiring projection data during the at least two scanning procedures including centered geometry projection data during the centered geometry scanning procedure and offset geometry projection data during the offset geometry scanning procedure; and
reconstructing the projection data acquired during the at least two scanning procedures together to generate volumetric data indicative of the object.
13. (canceled)
14. The method of claim 12, wherein the reconstruction combines the projection data acquired during the at least two scanning procedures to form a data set corresponding to an imaging scan performed by a single virtual detector in one position with respect to the source.
15. The method of claim 12, wherein the radiation sensitive detector is a flat detector, and further comprising transversely displacing the center of the radiation sensitive detector from the center of rotation in the transaxial plane during the at least one offset geometry scanning procedure.
16. (canceled)
17. The method of claim 12, wherein a faded weighting technique and an averaging technique are applied to an overlap region of the projection data acquired during the at least two scanning procedures during reconstruction.
18. The method of claim 12, further comprising administering a lower dose of radiation during the at least one offset geometry scanning procedure than during the at least one centered geometry scanning procedure.
19. The method of claim 18, wherein the dose of radiation administered during the at least one offset geometry scanning procedure is less than half of the radiation administered during the at least one centered geometry scanning procedure.
20. An apparatus for generating a motion map, the apparatus comprising:
a radiation source;
a radiation sensitive detector which detects radiation emitted by the source that has traversed an examination region; and
a reconstructor an image processor;
wherein the radiation source and the radiation sensitive detector are used to acquire projection data at a plurality of angular positions relative to an object disposed in the examination region;
wherein the reconstructor is used to generate a reference image from the projection data;
wherein reference projection data is obtained from a forward projection of the reference image;
wherein differences between the acquired projection data and the reference projection data are computed to determine line integral differences; and
wherein the image processor uses the line integral differences to generate a motion map indicative of the regions of a corresponding image reconstructed from the projection data that are affected by motion.
21. The apparatus of claim 20, wherein the image processor applies a windowing process to refine the motion map.
22. The apparatus of claim 20, wherein the image processor applies a normalization process to refine the motion map.
23. The apparatus of claim 20, wherein the image processor applies a volumetric median filter to refine the motion map.
24. The apparatus of claim 20, wherein the image processor applies a Gaussian blur to refine the motion map.
25. The apparatus of claim 20, wherein the apparatus is a cone-beam computed tomography imaging device.
26. The apparatus of claim 20, wherein the image processor processes the volumetric data for display on a user interface.
27. The apparatus of claim 20, wherein the motion map indicates the amount of motion correction to be applied to an image.
28. The apparatus of claim 27, wherein the image processor uses the motion map in a motion-compensated image reconstruction.
29. The apparatus of claim 28, wherein the image processor performs a reconstruction as a weighted average between a motion corrected reconstruction and a reconstruction not corrected for motion, wherein the weights are provided by the motion map.
30. The apparatus of claim 27, wherein the motion displacement in a motion-corrected reconstruction is adapted according to the motion map.
31. A method for generating a motion map, the method comprising the steps of:
acquiring projection data at a plurality of angular positions relative to an object disposed in an examination region;
reconstructing from the projection data to generate a reference image;
obtaining reference projection data from a forward projection of the reference image;
computing differences between the acquired projection data and the reference projection data to determine line integral differences; and
using the line integral differences to generate a motion map indicative of the regions of a corresponding image reconstructed from the projection data that are affected by motion.
32. The method of claim 31, further comprising the step of applying a windowing process to refine the motion map.
33. The method of claim 31, further comprising the steps of refining the motion map by normalizing the motion map, applying a volumetric median filter to the motion map, and applying a Gaussian blur to the motion map.
34. The method of claim 31, further comprising the step of using the motion map in conjunction with the corresponding image reconstructed from the projection data to detect regions of the reconstructed image that are affected by motion.
35. The method of claim 31, further comprising the step of using the motion map in conjunction with a motion correction technique to compensate for the effects of motion in the corresponding image reconstructed from the projection data.
36. The method of claim 35, further comprising compensating for motion only in regions of the corresponding image that are indicated to have been affected by motion by the motion map.
37. The method of claim 35, further comprising compensating for motion by applying a weighted value of motion correction to regions of the corresponding image reconstructed from the tomographic projection data, the weighted value being calculated for each region based upon a quantitative amount of motion indicated for each image region by the motion map.
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Cited By (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103222877A (en) * 2012-01-27 2013-07-31 株式会社东芝 X-ray CT system
US20140081131A1 (en) * 2012-09-18 2014-03-20 Yiannis Kyriakou Angiographic examination method
US20140226891A1 (en) * 2013-02-13 2014-08-14 Holger Kunze Method and Device for Correction of Movement Artifacts in a Computed Tomography Image
US20180139467A1 (en) * 2016-11-14 2018-05-17 Samsung Electronics Co., Ltd. Medical imaging apparatus, medical image processing method, and computer-readable recording medium related to the medical image processing method
US10008012B2 (en) 2015-12-11 2018-06-26 Shenyang Neusoft Medical Systems Co., Ltd. Image reconstruction
US10117632B2 (en) 2016-02-03 2018-11-06 Globus Medical, Inc. Portable medical imaging system with beam scanning collimator
US10163233B2 (en) 2015-12-11 2018-12-25 Shenyang Neusoft Medical Systems Co., Ltd. Image reconstruction
CN109419526A (en) * 2017-08-31 2019-03-05 通用电气公司 Method and system for locomotion evaluation and correction in the synthesis of digital breast tomography
US10292778B2 (en) 2014-04-24 2019-05-21 Globus Medical, Inc. Surgical instrument holder for use with a robotic surgical system
US10350013B2 (en) 2012-06-21 2019-07-16 Globus Medical, Inc. Surgical tool systems and methods
US10357184B2 (en) 2012-06-21 2019-07-23 Globus Medical, Inc. Surgical tool systems and method
US10357257B2 (en) 2014-07-14 2019-07-23 KB Medical SA Anti-skid surgical instrument for use in preparing holes in bone tissue
US10420616B2 (en) 2017-01-18 2019-09-24 Globus Medical, Inc. Robotic navigation of robotic surgical systems
US10448910B2 (en) 2016-02-03 2019-10-22 Globus Medical, Inc. Portable medical imaging system
US10485617B2 (en) 2012-06-21 2019-11-26 Globus Medical, Inc. Surgical robot platform
US10546423B2 (en) 2015-02-03 2020-01-28 Globus Medical, Inc. Surgeon head-mounted display apparatuses
US10548620B2 (en) 2014-01-15 2020-02-04 Globus Medical, Inc. Notched apparatus for guidance of an insertable instrument along an axis during spinal surgery
US10555782B2 (en) 2015-02-18 2020-02-11 Globus Medical, Inc. Systems and methods for performing minimally invasive spinal surgery with a robotic surgical system using a percutaneous technique
US10569794B2 (en) 2015-10-13 2020-02-25 Globus Medical, Inc. Stabilizer wheel assembly and methods of use
US10573023B2 (en) 2018-04-09 2020-02-25 Globus Medical, Inc. Predictive visualization of medical imaging scanner component movement
US10624710B2 (en) 2012-06-21 2020-04-21 Globus Medical, Inc. System and method for measuring depth of instrumentation
US10639112B2 (en) 2012-06-21 2020-05-05 Globus Medical, Inc. Infrared signal based position recognition system for use with a robot-assisted surgery
US10646283B2 (en) 2018-02-19 2020-05-12 Globus Medical Inc. Augmented reality navigation systems for use with robotic surgical systems and methods of their use
US10646298B2 (en) 2015-07-31 2020-05-12 Globus Medical, Inc. Robot arm and methods of use
US10646280B2 (en) 2012-06-21 2020-05-12 Globus Medical, Inc. System and method for surgical tool insertion using multiaxis force and moment feedback
US10653497B2 (en) 2006-02-16 2020-05-19 Globus Medical, Inc. Surgical tool systems and methods
US10660712B2 (en) 2011-04-01 2020-05-26 Globus Medical Inc. Robotic system and method for spinal and other surgeries
US10675094B2 (en) 2017-07-21 2020-06-09 Globus Medical Inc. Robot surgical platform
US10687905B2 (en) 2015-08-31 2020-06-23 KB Medical SA Robotic surgical systems and methods
US10758315B2 (en) 2012-06-21 2020-09-01 Globus Medical Inc. Method and system for improving 2D-3D registration convergence
US10765438B2 (en) 2014-07-14 2020-09-08 KB Medical SA Anti-skid surgical instrument for use in preparing holes in bone tissue
US10786313B2 (en) 2015-08-12 2020-09-29 Globus Medical, Inc. Devices and methods for temporary mounting of parts to bone
US10799298B2 (en) 2012-06-21 2020-10-13 Globus Medical Inc. Robotic fluoroscopic navigation
US10806471B2 (en) 2017-01-18 2020-10-20 Globus Medical, Inc. Universal instrument guide for robotic surgical systems, surgical instrument systems, and methods of their use
US10813704B2 (en) 2013-10-04 2020-10-27 Kb Medical, Sa Apparatus and systems for precise guidance of surgical tools
US10828120B2 (en) 2014-06-19 2020-11-10 Kb Medical, Sa Systems and methods for performing minimally invasive surgery
US10842461B2 (en) 2012-06-21 2020-11-24 Globus Medical, Inc. Systems and methods of checking registrations for surgical systems
US10842453B2 (en) 2016-02-03 2020-11-24 Globus Medical, Inc. Portable medical imaging system
US10866119B2 (en) 2016-03-14 2020-12-15 Globus Medical, Inc. Metal detector for detecting insertion of a surgical device into a hollow tube
US10864057B2 (en) 2017-01-18 2020-12-15 Kb Medical, Sa Universal instrument guide for robotic surgical systems, surgical instrument systems, and methods of their use
US10874466B2 (en) 2012-06-21 2020-12-29 Globus Medical, Inc. System and method for surgical tool insertion using multiaxis force and moment feedback
US10893912B2 (en) 2006-02-16 2021-01-19 Globus Medical Inc. Surgical tool systems and methods
US10898252B2 (en) 2017-11-09 2021-01-26 Globus Medical, Inc. Surgical robotic systems for bending surgical rods, and related methods and devices
US20210049795A1 (en) * 2019-10-29 2021-02-18 Shanghai United Imaging Healthcare Co., Ltd. Systems and methods for medical imaging
US10925681B2 (en) 2015-07-31 2021-02-23 Globus Medical Inc. Robot arm and methods of use
US10939968B2 (en) 2014-02-11 2021-03-09 Globus Medical Inc. Sterile handle for controlling a robotic surgical system from a sterile field
US10973594B2 (en) 2015-09-14 2021-04-13 Globus Medical, Inc. Surgical robotic systems and methods thereof
US11039893B2 (en) 2016-10-21 2021-06-22 Globus Medical, Inc. Robotic surgical systems
US11045179B2 (en) 2019-05-20 2021-06-29 Global Medical Inc Robot-mounted retractor system
US11045267B2 (en) 2012-06-21 2021-06-29 Globus Medical, Inc. Surgical robotic automation with tracking markers
US11058378B2 (en) 2016-02-03 2021-07-13 Globus Medical, Inc. Portable medical imaging system
US11071594B2 (en) 2017-03-16 2021-07-27 KB Medical SA Robotic navigation of robotic surgical systems
US11103316B2 (en) 2014-12-02 2021-08-31 Globus Medical Inc. Robot assisted volume removal during surgery
US11116576B2 (en) 2012-06-21 2021-09-14 Globus Medical Inc. Dynamic reference arrays and methods of use
US11134862B2 (en) 2017-11-10 2021-10-05 Globus Medical, Inc. Methods of selecting surgical implants and related devices
US11153555B1 (en) 2020-05-08 2021-10-19 Globus Medical Inc. Extended reality headset camera system for computer assisted navigation in surgery
US11207150B2 (en) 2020-02-19 2021-12-28 Globus Medical, Inc. Displaying a virtual model of a planned instrument attachment to ensure correct selection of physical instrument attachment
US11253216B2 (en) 2020-04-28 2022-02-22 Globus Medical Inc. Fixtures for fluoroscopic imaging systems and related navigation systems and methods
US11253327B2 (en) 2012-06-21 2022-02-22 Globus Medical, Inc. Systems and methods for automatically changing an end-effector on a surgical robot
US11278360B2 (en) 2018-11-16 2022-03-22 Globus Medical, Inc. End-effectors for surgical robotic systems having sealed optical components
US11298196B2 (en) 2012-06-21 2022-04-12 Globus Medical Inc. Surgical robotic automation with tracking markers and controlled tool advancement
US11317971B2 (en) 2012-06-21 2022-05-03 Globus Medical, Inc. Systems and methods related to robotic guidance in surgery
US11317973B2 (en) 2020-06-09 2022-05-03 Globus Medical, Inc. Camera tracking bar for computer assisted navigation during surgery
US11317978B2 (en) 2019-03-22 2022-05-03 Globus Medical, Inc. System for neuronavigation registration and robotic trajectory guidance, robotic surgery, and related methods and devices
US11337742B2 (en) 2018-11-05 2022-05-24 Globus Medical Inc Compliant orthopedic driver
US11357548B2 (en) 2017-11-09 2022-06-14 Globus Medical, Inc. Robotic rod benders and related mechanical and motor housings
US11382700B2 (en) 2020-05-08 2022-07-12 Globus Medical Inc. Extended reality headset tool tracking and control
US11382699B2 (en) 2020-02-10 2022-07-12 Globus Medical Inc. Extended reality visualization of optical tool tracking volume for computer assisted navigation in surgery
US11382549B2 (en) 2019-03-22 2022-07-12 Globus Medical, Inc. System for neuronavigation registration and robotic trajectory guidance, and related methods and devices
US11382713B2 (en) 2020-06-16 2022-07-12 Globus Medical, Inc. Navigated surgical system with eye to XR headset display calibration
US11395706B2 (en) 2012-06-21 2022-07-26 Globus Medical Inc. Surgical robot platform
US11399900B2 (en) 2012-06-21 2022-08-02 Globus Medical, Inc. Robotic systems providing co-registration using natural fiducials and related methods
US11419616B2 (en) 2019-03-22 2022-08-23 Globus Medical, Inc. System for neuronavigation registration and robotic trajectory guidance, robotic surgery, and related methods and devices
US11426178B2 (en) 2019-09-27 2022-08-30 Globus Medical Inc. Systems and methods for navigating a pin guide driver
US11439444B1 (en) 2021-07-22 2022-09-13 Globus Medical, Inc. Screw tower and rod reduction tool
US11439471B2 (en) 2012-06-21 2022-09-13 Globus Medical, Inc. Surgical tool system and method
US11464581B2 (en) 2020-01-28 2022-10-11 Globus Medical, Inc. Pose measurement chaining for extended reality surgical navigation in visible and near infrared spectrums
US11510684B2 (en) 2019-10-14 2022-11-29 Globus Medical, Inc. Rotary motion passive end effector for surgical robots in orthopedic surgeries
US11510750B2 (en) 2020-05-08 2022-11-29 Globus Medical, Inc. Leveraging two-dimensional digital imaging and communication in medicine imagery in three-dimensional extended reality applications
US11523785B2 (en) 2020-09-24 2022-12-13 Globus Medical, Inc. Increased cone beam computed tomography volume length without requiring stitching or longitudinal C-arm movement
US11571265B2 (en) 2019-03-22 2023-02-07 Globus Medical Inc. System for neuronavigation registration and robotic trajectory guidance, robotic surgery, and related methods and devices
US11571171B2 (en) 2019-09-24 2023-02-07 Globus Medical, Inc. Compound curve cable chain
US11589771B2 (en) 2012-06-21 2023-02-28 Globus Medical Inc. Method for recording probe movement and determining an extent of matter removed
US11602402B2 (en) 2018-12-04 2023-03-14 Globus Medical, Inc. Drill guide fixtures, cranial insertion fixtures, and related methods and robotic systems
US11607149B2 (en) 2012-06-21 2023-03-21 Globus Medical Inc. Surgical tool systems and method
US11628023B2 (en) 2019-07-10 2023-04-18 Globus Medical, Inc. Robotic navigational system for interbody implants
US11717350B2 (en) 2020-11-24 2023-08-08 Globus Medical Inc. Methods for robotic assistance and navigation in spinal surgery and related systems
US11737831B2 (en) 2020-09-02 2023-08-29 Globus Medical Inc. Surgical object tracking template generation for computer assisted navigation during surgical procedure
US11744655B2 (en) 2018-12-04 2023-09-05 Globus Medical, Inc. Drill guide fixtures, cranial insertion fixtures, and related methods and robotic systems
US11786324B2 (en) 2012-06-21 2023-10-17 Globus Medical, Inc. Surgical robotic automation with tracking markers
US11793570B2 (en) 2012-06-21 2023-10-24 Globus Medical Inc. Surgical robotic automation with tracking markers
US11794338B2 (en) 2017-11-09 2023-10-24 Globus Medical Inc. Robotic rod benders and related mechanical and motor housings
US11793588B2 (en) 2020-07-23 2023-10-24 Globus Medical, Inc. Sterile draping of robotic arms
US11806084B2 (en) 2019-03-22 2023-11-07 Globus Medical, Inc. System for neuronavigation registration and robotic trajectory guidance, and related methods and devices
US11850009B2 (en) 2021-07-06 2023-12-26 Globus Medical, Inc. Ultrasonic robotic surgical navigation
US11857149B2 (en) 2012-06-21 2024-01-02 Globus Medical, Inc. Surgical robotic systems with target trajectory deviation monitoring and related methods
US11857266B2 (en) 2012-06-21 2024-01-02 Globus Medical, Inc. System for a surveillance marker in robotic-assisted surgery
US11864839B2 (en) 2012-06-21 2024-01-09 Globus Medical Inc. Methods of adjusting a virtual implant and related surgical navigation systems
US11864745B2 (en) 2012-06-21 2024-01-09 Globus Medical, Inc. Surgical robotic system with retractor
US11864857B2 (en) 2019-09-27 2024-01-09 Globus Medical, Inc. Surgical robot with passive end effector
US11877807B2 (en) 2020-07-10 2024-01-23 Globus Medical, Inc Instruments for navigated orthopedic surgeries
US11883217B2 (en) 2016-02-03 2024-01-30 Globus Medical, Inc. Portable medical imaging system and method
US11890066B2 (en) 2019-09-30 2024-02-06 Globus Medical, Inc Surgical robot with passive end effector
US11896446B2 (en) 2012-06-21 2024-02-13 Globus Medical, Inc Surgical robotic automation with tracking markers
US11911115B2 (en) 2021-12-20 2024-02-27 Globus Medical Inc. Flat panel registration fixture and method of using same
US11911112B2 (en) 2020-10-27 2024-02-27 Globus Medical, Inc. Robotic navigational system
US11918313B2 (en) 2019-03-15 2024-03-05 Globus Medical Inc. Active end effectors for surgical robots
US11941814B2 (en) 2020-11-04 2024-03-26 Globus Medical Inc. Auto segmentation using 2-D images taken during 3-D imaging spin
US11944325B2 (en) 2019-03-22 2024-04-02 Globus Medical, Inc. System for neuronavigation registration and robotic trajectory guidance, robotic surgery, and related methods and devices
CN117838169A (en) * 2024-03-08 2024-04-09 江苏一影医疗设备有限公司 Imaging method, system and equipment based on standing position CBCT
US11963755B2 (en) 2012-06-21 2024-04-23 Globus Medical Inc. Apparatus for recording probe movement
US11974886B2 (en) 2016-04-11 2024-05-07 Globus Medical Inc. Surgical tool systems and methods
US11974822B2 (en) 2012-06-21 2024-05-07 Globus Medical Inc. Method for a surveillance marker in robotic-assisted surgery
US11992373B2 (en) 2019-12-10 2024-05-28 Globus Medical, Inc Augmented reality headset with varied opacity for navigated robotic surgery
US12004905B2 (en) 2012-06-21 2024-06-11 Globus Medical, Inc. Medical imaging systems using robotic actuators and related methods

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9129425B2 (en) * 2010-12-24 2015-09-08 Fei Company Reconstruction of dynamic multi-dimensional image data
US20140003688A1 (en) * 2011-03-17 2014-01-02 Koninklijke Philips N.V. Multiple modality cardiac imaging
US9986983B2 (en) 2014-10-31 2018-06-05 Covidien Lp Computed tomography enhanced fluoroscopic system, device, and method of utilizing the same
CN104352246A (en) * 2014-12-02 2015-02-18 东南大学 Cone beam CT (computed tomography) area-of-interest scanning method based on visualization
CN104545976B (en) * 2014-12-30 2017-04-19 上海优益基医疗器械有限公司 Computer body layer photographing method and device
US10716525B2 (en) 2015-08-06 2020-07-21 Covidien Lp System and method for navigating to target and performing procedure on target utilizing fluoroscopic-based local three dimensional volume reconstruction
US10702226B2 (en) 2015-08-06 2020-07-07 Covidien Lp System and method for local three dimensional volume reconstruction using a standard fluoroscope
US10674982B2 (en) 2015-08-06 2020-06-09 Covidien Lp System and method for local three dimensional volume reconstruction using a standard fluoroscope
US11172895B2 (en) 2015-12-07 2021-11-16 Covidien Lp Visualization, navigation, and planning with electromagnetic navigation bronchoscopy and cone beam computed tomography integrated
US11051886B2 (en) 2016-09-27 2021-07-06 Covidien Lp Systems and methods for performing a surgical navigation procedure
US10339678B2 (en) * 2016-11-16 2019-07-02 University Of Central Florida Research Foundation, Inc. System and method for motion estimation and compensation in helical computed tomography
EP3559911B1 (en) * 2016-12-21 2020-05-20 Koninklijke Philips N.V. Redundancy weighting for short scan off-center detector x-ray tomography
CN106780395B (en) * 2016-12-30 2019-12-20 上海联影医疗科技有限公司 Method and device for removing motion blur in projection image of CBCT (cone beam computed tomography) system
US10699448B2 (en) 2017-06-29 2020-06-30 Covidien Lp System and method for identifying, marking and navigating to a target using real time two dimensional fluoroscopic data
US10893843B2 (en) 2017-10-10 2021-01-19 Covidien Lp System and method for identifying and marking a target in a fluoroscopic three-dimensional reconstruction
CN107714072B (en) * 2017-11-20 2019-09-20 中国科学院高能物理研究所 Compensation method, computer tomographic scanning imaging method and the system of missing data
US10905498B2 (en) 2018-02-08 2021-02-02 Covidien Lp System and method for catheter detection in fluoroscopic images and updating displayed position of catheter
KR20190103816A (en) 2018-02-28 2019-09-05 삼성전자주식회사 Method and apparatus for correcting the computed tomographic image
EP3618001A1 (en) * 2018-08-30 2020-03-04 Koninklijke Philips N.V. Efficient motion-compensation in cone beam computed tomography based on data consistency
JP2022509306A (en) 2018-11-30 2022-01-20 アキュレイ インコーポレイテッド Methods and equipment to improve scatter evaluation and scatter correction in imaging
CN113424227B (en) * 2019-01-11 2023-07-25 中佛罗里达大学研究基金会公司 Motion estimation and compensation in Cone Beam Computed Tomography (CBCT)
CN110517330B (en) * 2019-08-07 2021-05-28 北京航空航天大学 Industrial cone beam CT reconstruction method in offset scanning mode
CN111528890B (en) * 2020-05-09 2024-03-15 上海联影医疗科技股份有限公司 Medical image acquisition method and system
CN111896566B (en) * 2020-07-20 2023-07-18 上海交通大学 Device and method for increasing imaging range of synchrotron radiation light source
CN112221022A (en) * 2020-09-24 2021-01-15 西安大医集团股份有限公司 Imaging system, method and radiotherapy system
US11647975B2 (en) 2021-06-04 2023-05-16 Accuray, Inc. Radiotherapy apparatus and methods for treatment and imaging using hybrid MeV-keV, multi-energy data acquisition for enhanced imaging
US11605186B2 (en) 2021-06-30 2023-03-14 Accuray, Inc. Anchored kernel scatter estimate
US11794039B2 (en) * 2021-07-13 2023-10-24 Accuray, Inc. Multimodal radiation apparatus and methods
US11854123B2 (en) 2021-07-23 2023-12-26 Accuray, Inc. Sparse background measurement and correction for improving imaging

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6546068B1 (en) * 1999-01-19 2003-04-08 Fuji Photo Film Co., Ltd. Image data acquisition method and image data acquisition device
US20040013225A1 (en) * 2002-03-19 2004-01-22 Breakaway Imaging, Llc Systems and methods for imaging large field-of-view objects
US20040179643A1 (en) * 2002-08-21 2004-09-16 Breakaway Imaging, Llc, Littleton, Ma Apparatus and method for reconstruction of volumetric images in a divergent scanning computed tomography system
US20040258195A1 (en) * 2003-06-17 2004-12-23 Yukihiro Hara Diagnostic X-ray system and CT image production method
GB2422759A (en) * 2004-08-05 2006-08-02 Elekta Ab Rotatable X-ray scan apparatus with cone beam offset
US20080049891A1 (en) * 2006-08-28 2008-02-28 Zhye Yin Methods for analytic reconstruction for mult-source inverse geometry ct
US20080089468A1 (en) * 2006-09-01 2008-04-17 Siemens Aktiengesellschaft Method for reconstructing a three-dimensional image volume and x-ray devices

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2614083B2 (en) * 1976-04-01 1979-02-08 Siemens Ag, 1000 Berlin Und 8000 Muenchen X-ray film device for the production of transverse slice images
US4670892A (en) * 1977-11-15 1987-06-02 Philips Medical Systems, Inc. Method and apparatus for computed tomography of portions of a body plane
JP2508078B2 (en) 1987-04-30 1996-06-19 株式会社島津製作所 X-ray image processing device
US5032990A (en) * 1989-05-30 1991-07-16 General Electric Company Translate rotate scanning method for x-ray imaging
US5233518A (en) 1989-11-13 1993-08-03 General Electric Company Extrapolative reconstruction method for helical scanning
JP2589613B2 (en) * 1991-09-17 1997-03-12 株式会社日立製作所 X-ray CT imaging method and X-ray CT apparatus
US5319693A (en) * 1992-12-30 1994-06-07 General Electric Company Three dimensional computerized tomography scanning configuration for imaging large objects with smaller area detectors
JP3548339B2 (en) 1996-06-12 2004-07-28 株式会社日立メディコ X-ray equipment
JP3540916B2 (en) * 1997-06-26 2004-07-07 株式会社日立メディコ 3D X-ray CT system
WO2000062674A1 (en) * 1999-04-15 2000-10-26 General Electric Company Half field of view reduced-size ct detector
US6463118B2 (en) * 2000-12-29 2002-10-08 Ge Medical Systems Global Technology Company, Llc Computed tomography (CT) weighting for high quality image recontruction
US6643351B2 (en) * 2001-03-12 2003-11-04 Shimadzu Corporation Radiographic apparatus
US6683935B2 (en) * 2001-09-28 2004-01-27 Bio-Imaging Research, Inc. Computed tomography with virtual tilt and angulation
JP2004136021A (en) * 2002-10-21 2004-05-13 Toshiba Corp Concentrated irradiation type radiotherapy apparatus
JP2004173856A (en) * 2002-11-26 2004-06-24 Canon Inc Digital x-ray tomography apparatus
JP2004180715A (en) * 2002-11-29 2004-07-02 Toshiba Corp X-ray computed tomography apparatus
CN1809841B (en) * 2003-06-18 2010-05-12 皇家飞利浦电子股份有限公司 Motion compensated reconstruction method, equipment and system
US7333587B2 (en) 2004-02-27 2008-02-19 General Electric Company Method and system for imaging using multiple offset X-ray emission points
US7630528B2 (en) * 2004-03-02 2009-12-08 Koninklijke Philips Electronics N.V. Motion compensation
US6956925B1 (en) * 2004-03-29 2005-10-18 Ge Medical Systems Global Technology Company, Llc Methods and systems for multi-modality imaging
US7142629B2 (en) * 2004-03-31 2006-11-28 General Electric Company Stationary computed tomography system and method
JP2005334230A (en) * 2004-05-26 2005-12-08 Ge Medical Systems Global Technology Co Llc Radiation ct equipment and image reconstruction method using the same
US20050265523A1 (en) 2004-05-28 2005-12-01 Strobel Norbert K C-arm device with adjustable detector offset for cone beam imaging involving partial circle scan trajectories
EP1799107A1 (en) * 2004-10-06 2007-06-27 Philips Intellectual Property & Standards GmbH Computed tomography method
US7272205B2 (en) * 2004-11-17 2007-09-18 Purdue Research Foundation Methods, apparatus, and software to facilitate computing the elements of a forward projection matrix
EP1828985A1 (en) 2004-11-24 2007-09-05 Wisconsin Alumni Research Foundation Fan-beam and cone-beam image reconstruction using filtered backprojection of differentiated projection data
DE102004057308A1 (en) * 2004-11-26 2006-07-13 Siemens Ag Angiographic X-ray diagnostic device for rotational angiography
US7062006B1 (en) 2005-01-19 2006-06-13 The Board Of Trustees Of The Leland Stanford Junior University Computed tomography with increased field of view
WO2007020318A2 (en) * 2005-08-17 2007-02-22 Palodex Group Oy X-ray imaging apparatus and x-ray imaging method for eccentric ct scanning
US7783096B2 (en) * 2005-10-17 2010-08-24 Siemens Corporation Device systems and methods for imaging
DE102006046034A1 (en) * 2006-02-01 2007-08-16 Siemens Ag X-ray CT system for producing projective and tomographic phase-contrast images
WO2007130433A2 (en) 2006-05-02 2007-11-15 Wisconsin Alumni Research Foundation X-ray system for use in image guided procedures
CN100570343C (en) 2006-06-13 2009-12-16 北京航空航天大学 Wide view-field three-D CT imaging method
US7388940B1 (en) * 2006-11-24 2008-06-17 General Electric Company Architectures for cardiac CT based on area x-ray sources

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6546068B1 (en) * 1999-01-19 2003-04-08 Fuji Photo Film Co., Ltd. Image data acquisition method and image data acquisition device
US20040013225A1 (en) * 2002-03-19 2004-01-22 Breakaway Imaging, Llc Systems and methods for imaging large field-of-view objects
US20040179643A1 (en) * 2002-08-21 2004-09-16 Breakaway Imaging, Llc, Littleton, Ma Apparatus and method for reconstruction of volumetric images in a divergent scanning computed tomography system
US20040258195A1 (en) * 2003-06-17 2004-12-23 Yukihiro Hara Diagnostic X-ray system and CT image production method
GB2422759A (en) * 2004-08-05 2006-08-02 Elekta Ab Rotatable X-ray scan apparatus with cone beam offset
US20080049891A1 (en) * 2006-08-28 2008-02-28 Zhye Yin Methods for analytic reconstruction for mult-source inverse geometry ct
US20080089468A1 (en) * 2006-09-01 2008-04-17 Siemens Aktiengesellschaft Method for reconstructing a three-dimensional image volume and x-ray devices

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
21CFR1020.30, Code of Federal Regulation, Title 21, Volume 8, Section 1020.30, Revised 1 April 2007 *
21CFR1020.31, Code of Federal Regulation, Title 21, Volume 8, Section 1020.31, Revised 1 April 2013 *
Lillian Gill, Director of Compliance, Resource manual for compliance test parameters of diagnostic x-ray systems, Food and Drug Administration, 15 July 1999 *

Cited By (195)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10653497B2 (en) 2006-02-16 2020-05-19 Globus Medical, Inc. Surgical tool systems and methods
US11628039B2 (en) 2006-02-16 2023-04-18 Globus Medical Inc. Surgical tool systems and methods
US10893912B2 (en) 2006-02-16 2021-01-19 Globus Medical Inc. Surgical tool systems and methods
US11744648B2 (en) 2011-04-01 2023-09-05 Globus Medicall, Inc. Robotic system and method for spinal and other surgeries
US11202681B2 (en) 2011-04-01 2021-12-21 Globus Medical, Inc. Robotic system and method for spinal and other surgeries
US10660712B2 (en) 2011-04-01 2020-05-26 Globus Medical Inc. Robotic system and method for spinal and other surgeries
US20130195240A1 (en) * 2012-01-27 2013-08-01 Toshiba Medical Systems Corporation X-ray ct system
CN103222877A (en) * 2012-01-27 2013-07-31 株式会社东芝 X-ray CT system
US9782142B2 (en) * 2012-01-27 2017-10-10 Toshiba Medical Systems Corporation X-ray CT system
US11045267B2 (en) 2012-06-21 2021-06-29 Globus Medical, Inc. Surgical robotic automation with tracking markers
US11819283B2 (en) 2012-06-21 2023-11-21 Globus Medical Inc. Systems and methods related to robotic guidance in surgery
US11116576B2 (en) 2012-06-21 2021-09-14 Globus Medical Inc. Dynamic reference arrays and methods of use
US10350013B2 (en) 2012-06-21 2019-07-16 Globus Medical, Inc. Surgical tool systems and methods
US10357184B2 (en) 2012-06-21 2019-07-23 Globus Medical, Inc. Surgical tool systems and method
US11911225B2 (en) 2012-06-21 2024-02-27 Globus Medical Inc. Method and system for improving 2D-3D registration convergence
US11684433B2 (en) 2012-06-21 2023-06-27 Globus Medical Inc. Surgical tool systems and method
US11607149B2 (en) 2012-06-21 2023-03-21 Globus Medical Inc. Surgical tool systems and method
US10485617B2 (en) 2012-06-21 2019-11-26 Globus Medical, Inc. Surgical robot platform
US10531927B2 (en) 2012-06-21 2020-01-14 Globus Medical, Inc. Methods for performing invasive medical procedures using a surgical robot
US11684431B2 (en) 2012-06-21 2023-06-27 Globus Medical, Inc. Surgical robot platform
US11103317B2 (en) 2012-06-21 2021-08-31 Globus Medical, Inc. Surgical robot platform
US11589771B2 (en) 2012-06-21 2023-02-28 Globus Medical Inc. Method for recording probe movement and determining an extent of matter removed
US11690687B2 (en) 2012-06-21 2023-07-04 Globus Medical Inc. Methods for performing medical procedures using a surgical robot
US12004905B2 (en) 2012-06-21 2024-06-11 Globus Medical, Inc. Medical imaging systems using robotic actuators and related methods
US11135022B2 (en) 2012-06-21 2021-10-05 Globus Medical, Inc. Surgical robot platform
US10624710B2 (en) 2012-06-21 2020-04-21 Globus Medical, Inc. System and method for measuring depth of instrumentation
US10639112B2 (en) 2012-06-21 2020-05-05 Globus Medical, Inc. Infrared signal based position recognition system for use with a robot-assisted surgery
US11896446B2 (en) 2012-06-21 2024-02-13 Globus Medical, Inc Surgical robotic automation with tracking markers
US11439471B2 (en) 2012-06-21 2022-09-13 Globus Medical, Inc. Surgical tool system and method
US11963755B2 (en) 2012-06-21 2024-04-23 Globus Medical Inc. Apparatus for recording probe movement
US10646280B2 (en) 2012-06-21 2020-05-12 Globus Medical, Inc. System and method for surgical tool insertion using multiaxis force and moment feedback
US11786324B2 (en) 2012-06-21 2023-10-17 Globus Medical, Inc. Surgical robotic automation with tracking markers
US11399900B2 (en) 2012-06-21 2022-08-02 Globus Medical, Inc. Robotic systems providing co-registration using natural fiducials and related methods
US11395706B2 (en) 2012-06-21 2022-07-26 Globus Medical Inc. Surgical robot platform
US11793570B2 (en) 2012-06-21 2023-10-24 Globus Medical Inc. Surgical robotic automation with tracking markers
US11026756B2 (en) 2012-06-21 2021-06-08 Globus Medical, Inc. Surgical robot platform
US10758315B2 (en) 2012-06-21 2020-09-01 Globus Medical Inc. Method and system for improving 2D-3D registration convergence
US11819365B2 (en) 2012-06-21 2023-11-21 Globus Medical, Inc. System and method for measuring depth of instrumentation
US11109922B2 (en) 2012-06-21 2021-09-07 Globus Medical, Inc. Surgical tool systems and method
US10799298B2 (en) 2012-06-21 2020-10-13 Globus Medical Inc. Robotic fluoroscopic navigation
US11331153B2 (en) 2012-06-21 2022-05-17 Globus Medical, Inc. Surgical robot platform
US11191598B2 (en) 2012-06-21 2021-12-07 Globus Medical, Inc. Surgical robot platform
US11864745B2 (en) 2012-06-21 2024-01-09 Globus Medical, Inc. Surgical robotic system with retractor
US11253327B2 (en) 2012-06-21 2022-02-22 Globus Medical, Inc. Systems and methods for automatically changing an end-effector on a surgical robot
US10835328B2 (en) 2012-06-21 2020-11-17 Globus Medical, Inc. Surgical robot platform
US10835326B2 (en) 2012-06-21 2020-11-17 Globus Medical Inc. Surgical robot platform
US10842461B2 (en) 2012-06-21 2020-11-24 Globus Medical, Inc. Systems and methods of checking registrations for surgical systems
US11857149B2 (en) 2012-06-21 2024-01-02 Globus Medical, Inc. Surgical robotic systems with target trajectory deviation monitoring and related methods
US11857266B2 (en) 2012-06-21 2024-01-02 Globus Medical, Inc. System for a surveillance marker in robotic-assisted surgery
US11317971B2 (en) 2012-06-21 2022-05-03 Globus Medical, Inc. Systems and methods related to robotic guidance in surgery
US11298196B2 (en) 2012-06-21 2022-04-12 Globus Medical Inc. Surgical robotic automation with tracking markers and controlled tool advancement
US10874466B2 (en) 2012-06-21 2020-12-29 Globus Medical, Inc. System and method for surgical tool insertion using multiaxis force and moment feedback
US11284949B2 (en) 2012-06-21 2022-03-29 Globus Medical, Inc. Surgical robot platform
US11974822B2 (en) 2012-06-21 2024-05-07 Globus Medical Inc. Method for a surveillance marker in robotic-assisted surgery
US10912617B2 (en) 2012-06-21 2021-02-09 Globus Medical, Inc. Surgical robot platform
US11864839B2 (en) 2012-06-21 2024-01-09 Globus Medical Inc. Methods of adjusting a virtual implant and related surgical navigation systems
US20140081131A1 (en) * 2012-09-18 2014-03-20 Yiannis Kyriakou Angiographic examination method
US9320488B2 (en) * 2013-02-13 2016-04-26 Siemens Aktiengesellschaft Method and device for correction of movement artifacts in a computed tomography image
US20140226891A1 (en) * 2013-02-13 2014-08-14 Holger Kunze Method and Device for Correction of Movement Artifacts in a Computed Tomography Image
US11896363B2 (en) 2013-03-15 2024-02-13 Globus Medical Inc. Surgical robot platform
US10813704B2 (en) 2013-10-04 2020-10-27 Kb Medical, Sa Apparatus and systems for precise guidance of surgical tools
US11172997B2 (en) 2013-10-04 2021-11-16 Kb Medical, Sa Apparatus and systems for precise guidance of surgical tools
US11737766B2 (en) 2014-01-15 2023-08-29 Globus Medical Inc. Notched apparatus for guidance of an insertable instrument along an axis during spinal surgery
US10548620B2 (en) 2014-01-15 2020-02-04 Globus Medical, Inc. Notched apparatus for guidance of an insertable instrument along an axis during spinal surgery
US10939968B2 (en) 2014-02-11 2021-03-09 Globus Medical Inc. Sterile handle for controlling a robotic surgical system from a sterile field
US11793583B2 (en) 2014-04-24 2023-10-24 Globus Medical Inc. Surgical instrument holder for use with a robotic surgical system
US10828116B2 (en) 2014-04-24 2020-11-10 Kb Medical, Sa Surgical instrument holder for use with a robotic surgical system
US10292778B2 (en) 2014-04-24 2019-05-21 Globus Medical, Inc. Surgical instrument holder for use with a robotic surgical system
US10828120B2 (en) 2014-06-19 2020-11-10 Kb Medical, Sa Systems and methods for performing minimally invasive surgery
US10765438B2 (en) 2014-07-14 2020-09-08 KB Medical SA Anti-skid surgical instrument for use in preparing holes in bone tissue
US10945742B2 (en) 2014-07-14 2021-03-16 Globus Medical Inc. Anti-skid surgical instrument for use in preparing holes in bone tissue
US10357257B2 (en) 2014-07-14 2019-07-23 KB Medical SA Anti-skid surgical instrument for use in preparing holes in bone tissue
US11534179B2 (en) 2014-07-14 2022-12-27 Globus Medical, Inc. Anti-skid surgical instrument for use in preparing holes in bone tissue
US11103316B2 (en) 2014-12-02 2021-08-31 Globus Medical Inc. Robot assisted volume removal during surgery
US11763531B2 (en) 2015-02-03 2023-09-19 Globus Medical, Inc. Surgeon head-mounted display apparatuses
US12002171B2 (en) 2015-02-03 2024-06-04 Globus Medical, Inc Surgeon head-mounted display apparatuses
US10546423B2 (en) 2015-02-03 2020-01-28 Globus Medical, Inc. Surgeon head-mounted display apparatuses
US11734901B2 (en) 2015-02-03 2023-08-22 Globus Medical, Inc. Surgeon head-mounted display apparatuses
US10580217B2 (en) 2015-02-03 2020-03-03 Globus Medical, Inc. Surgeon head-mounted display apparatuses
US11461983B2 (en) 2015-02-03 2022-10-04 Globus Medical, Inc. Surgeon head-mounted display apparatuses
US10650594B2 (en) 2015-02-03 2020-05-12 Globus Medical Inc. Surgeon head-mounted display apparatuses
US11176750B2 (en) 2015-02-03 2021-11-16 Globus Medical, Inc. Surgeon head-mounted display apparatuses
US11217028B2 (en) 2015-02-03 2022-01-04 Globus Medical, Inc. Surgeon head-mounted display apparatuses
US11062522B2 (en) 2015-02-03 2021-07-13 Global Medical Inc Surgeon head-mounted display apparatuses
US11266470B2 (en) 2015-02-18 2022-03-08 KB Medical SA Systems and methods for performing minimally invasive spinal surgery with a robotic surgical system using a percutaneous technique
US10555782B2 (en) 2015-02-18 2020-02-11 Globus Medical, Inc. Systems and methods for performing minimally invasive spinal surgery with a robotic surgical system using a percutaneous technique
US11672622B2 (en) 2015-07-31 2023-06-13 Globus Medical, Inc. Robot arm and methods of use
US10646298B2 (en) 2015-07-31 2020-05-12 Globus Medical, Inc. Robot arm and methods of use
US11337769B2 (en) 2015-07-31 2022-05-24 Globus Medical, Inc. Robot arm and methods of use
US10925681B2 (en) 2015-07-31 2021-02-23 Globus Medical Inc. Robot arm and methods of use
US10786313B2 (en) 2015-08-12 2020-09-29 Globus Medical, Inc. Devices and methods for temporary mounting of parts to bone
US11751950B2 (en) 2015-08-12 2023-09-12 Globus Medical Inc. Devices and methods for temporary mounting of parts to bone
US10687905B2 (en) 2015-08-31 2020-06-23 KB Medical SA Robotic surgical systems and methods
US11872000B2 (en) 2015-08-31 2024-01-16 Globus Medical, Inc Robotic surgical systems and methods
US10973594B2 (en) 2015-09-14 2021-04-13 Globus Medical, Inc. Surgical robotic systems and methods thereof
US11066090B2 (en) 2015-10-13 2021-07-20 Globus Medical, Inc. Stabilizer wheel assembly and methods of use
US10569794B2 (en) 2015-10-13 2020-02-25 Globus Medical, Inc. Stabilizer wheel assembly and methods of use
US10163233B2 (en) 2015-12-11 2018-12-25 Shenyang Neusoft Medical Systems Co., Ltd. Image reconstruction
US10008012B2 (en) 2015-12-11 2018-06-26 Shenyang Neusoft Medical Systems Co., Ltd. Image reconstruction
US12016714B2 (en) 2016-02-03 2024-06-25 Globus Medical Inc. Portable medical imaging system
US11523784B2 (en) 2016-02-03 2022-12-13 Globus Medical, Inc. Portable medical imaging system
US11883217B2 (en) 2016-02-03 2024-01-30 Globus Medical, Inc. Portable medical imaging system and method
US11986333B2 (en) 2016-02-03 2024-05-21 Globus Medical Inc. Portable medical imaging system
US10448910B2 (en) 2016-02-03 2019-10-22 Globus Medical, Inc. Portable medical imaging system
US10842453B2 (en) 2016-02-03 2020-11-24 Globus Medical, Inc. Portable medical imaging system
US10849580B2 (en) 2016-02-03 2020-12-01 Globus Medical Inc. Portable medical imaging system
US10687779B2 (en) 2016-02-03 2020-06-23 Globus Medical, Inc. Portable medical imaging system with beam scanning collimator
US11801022B2 (en) 2016-02-03 2023-10-31 Globus Medical, Inc. Portable medical imaging system
US10117632B2 (en) 2016-02-03 2018-11-06 Globus Medical, Inc. Portable medical imaging system with beam scanning collimator
US11058378B2 (en) 2016-02-03 2021-07-13 Globus Medical, Inc. Portable medical imaging system
US10866119B2 (en) 2016-03-14 2020-12-15 Globus Medical, Inc. Metal detector for detecting insertion of a surgical device into a hollow tube
US11668588B2 (en) 2016-03-14 2023-06-06 Globus Medical Inc. Metal detector for detecting insertion of a surgical device into a hollow tube
US11920957B2 (en) 2016-03-14 2024-03-05 Globus Medical, Inc. Metal detector for detecting insertion of a surgical device into a hollow tube
US11974886B2 (en) 2016-04-11 2024-05-07 Globus Medical Inc. Surgical tool systems and methods
US11806100B2 (en) 2016-10-21 2023-11-07 Kb Medical, Sa Robotic surgical systems
US11039893B2 (en) 2016-10-21 2021-06-22 Globus Medical, Inc. Robotic surgical systems
US20180139467A1 (en) * 2016-11-14 2018-05-17 Samsung Electronics Co., Ltd. Medical imaging apparatus, medical image processing method, and computer-readable recording medium related to the medical image processing method
US11529195B2 (en) 2017-01-18 2022-12-20 Globus Medical Inc. Robotic navigation of robotic surgical systems
US10864057B2 (en) 2017-01-18 2020-12-15 Kb Medical, Sa Universal instrument guide for robotic surgical systems, surgical instrument systems, and methods of their use
US10806471B2 (en) 2017-01-18 2020-10-20 Globus Medical, Inc. Universal instrument guide for robotic surgical systems, surgical instrument systems, and methods of their use
US10420616B2 (en) 2017-01-18 2019-09-24 Globus Medical, Inc. Robotic navigation of robotic surgical systems
US11779408B2 (en) 2017-01-18 2023-10-10 Globus Medical, Inc. Robotic navigation of robotic surgical systems
US11813030B2 (en) 2017-03-16 2023-11-14 Globus Medical, Inc. Robotic navigation of robotic surgical systems
US11071594B2 (en) 2017-03-16 2021-07-27 KB Medical SA Robotic navigation of robotic surgical systems
US11771499B2 (en) 2017-07-21 2023-10-03 Globus Medical Inc. Robot surgical platform
US10675094B2 (en) 2017-07-21 2020-06-09 Globus Medical Inc. Robot surgical platform
US11253320B2 (en) 2017-07-21 2022-02-22 Globus Medical Inc. Robot surgical platform
US11135015B2 (en) 2017-07-21 2021-10-05 Globus Medical, Inc. Robot surgical platform
CN109419526A (en) * 2017-08-31 2019-03-05 通用电气公司 Method and system for locomotion evaluation and correction in the synthesis of digital breast tomography
US11357548B2 (en) 2017-11-09 2022-06-14 Globus Medical, Inc. Robotic rod benders and related mechanical and motor housings
US11794338B2 (en) 2017-11-09 2023-10-24 Globus Medical Inc. Robotic rod benders and related mechanical and motor housings
US11382666B2 (en) 2017-11-09 2022-07-12 Globus Medical Inc. Methods providing bend plans for surgical rods and related controllers and computer program products
US10898252B2 (en) 2017-11-09 2021-01-26 Globus Medical, Inc. Surgical robotic systems for bending surgical rods, and related methods and devices
US11134862B2 (en) 2017-11-10 2021-10-05 Globus Medical, Inc. Methods of selecting surgical implants and related devices
US11786144B2 (en) 2017-11-10 2023-10-17 Globus Medical, Inc. Methods of selecting surgical implants and related devices
US10646283B2 (en) 2018-02-19 2020-05-12 Globus Medical Inc. Augmented reality navigation systems for use with robotic surgical systems and methods of their use
US11100668B2 (en) 2018-04-09 2021-08-24 Globus Medical, Inc. Predictive visualization of medical imaging scanner component movement
US11694355B2 (en) 2018-04-09 2023-07-04 Globus Medical, Inc. Predictive visualization of medical imaging scanner component movement
US10573023B2 (en) 2018-04-09 2020-02-25 Globus Medical, Inc. Predictive visualization of medical imaging scanner component movement
US11832863B2 (en) 2018-11-05 2023-12-05 Globus Medical, Inc. Compliant orthopedic driver
US11751927B2 (en) 2018-11-05 2023-09-12 Globus Medical Inc. Compliant orthopedic driver
US11337742B2 (en) 2018-11-05 2022-05-24 Globus Medical Inc Compliant orthopedic driver
US11278360B2 (en) 2018-11-16 2022-03-22 Globus Medical, Inc. End-effectors for surgical robotic systems having sealed optical components
US11744655B2 (en) 2018-12-04 2023-09-05 Globus Medical, Inc. Drill guide fixtures, cranial insertion fixtures, and related methods and robotic systems
US11602402B2 (en) 2018-12-04 2023-03-14 Globus Medical, Inc. Drill guide fixtures, cranial insertion fixtures, and related methods and robotic systems
US11969224B2 (en) 2018-12-04 2024-04-30 Globus Medical, Inc. Drill guide fixtures, cranial insertion fixtures, and related methods and robotic systems
US11918313B2 (en) 2019-03-15 2024-03-05 Globus Medical Inc. Active end effectors for surgical robots
US11744598B2 (en) 2019-03-22 2023-09-05 Globus Medical, Inc. System for neuronavigation registration and robotic trajectory guidance, robotic surgery, and related methods and devices
US11419616B2 (en) 2019-03-22 2022-08-23 Globus Medical, Inc. System for neuronavigation registration and robotic trajectory guidance, robotic surgery, and related methods and devices
US11850012B2 (en) 2019-03-22 2023-12-26 Globus Medical, Inc. System for neuronavigation registration and robotic trajectory guidance, robotic surgery, and related methods and devices
US11317978B2 (en) 2019-03-22 2022-05-03 Globus Medical, Inc. System for neuronavigation registration and robotic trajectory guidance, robotic surgery, and related methods and devices
US11944325B2 (en) 2019-03-22 2024-04-02 Globus Medical, Inc. System for neuronavigation registration and robotic trajectory guidance, robotic surgery, and related methods and devices
US11571265B2 (en) 2019-03-22 2023-02-07 Globus Medical Inc. System for neuronavigation registration and robotic trajectory guidance, robotic surgery, and related methods and devices
US11806084B2 (en) 2019-03-22 2023-11-07 Globus Medical, Inc. System for neuronavigation registration and robotic trajectory guidance, and related methods and devices
US11382549B2 (en) 2019-03-22 2022-07-12 Globus Medical, Inc. System for neuronavigation registration and robotic trajectory guidance, and related methods and devices
US11737696B2 (en) 2019-03-22 2023-08-29 Globus Medical, Inc. System for neuronavigation registration and robotic trajectory guidance, and related methods and devices
US11045179B2 (en) 2019-05-20 2021-06-29 Global Medical Inc Robot-mounted retractor system
US11628023B2 (en) 2019-07-10 2023-04-18 Globus Medical, Inc. Robotic navigational system for interbody implants
US11571171B2 (en) 2019-09-24 2023-02-07 Globus Medical, Inc. Compound curve cable chain
US11864857B2 (en) 2019-09-27 2024-01-09 Globus Medical, Inc. Surgical robot with passive end effector
US11426178B2 (en) 2019-09-27 2022-08-30 Globus Medical Inc. Systems and methods for navigating a pin guide driver
US11890066B2 (en) 2019-09-30 2024-02-06 Globus Medical, Inc Surgical robot with passive end effector
US11510684B2 (en) 2019-10-14 2022-11-29 Globus Medical, Inc. Rotary motion passive end effector for surgical robots in orthopedic surgeries
US11844532B2 (en) 2019-10-14 2023-12-19 Globus Medical, Inc. Rotary motion passive end effector for surgical robots in orthopedic surgeries
US11776170B2 (en) * 2019-10-29 2023-10-03 Shanghai United Imaging Healthcare Co., Ltd. Systems and methods for medical imaging
US20210049795A1 (en) * 2019-10-29 2021-02-18 Shanghai United Imaging Healthcare Co., Ltd. Systems and methods for medical imaging
US11992373B2 (en) 2019-12-10 2024-05-28 Globus Medical, Inc Augmented reality headset with varied opacity for navigated robotic surgery
US11464581B2 (en) 2020-01-28 2022-10-11 Globus Medical, Inc. Pose measurement chaining for extended reality surgical navigation in visible and near infrared spectrums
US11883117B2 (en) 2020-01-28 2024-01-30 Globus Medical, Inc. Pose measurement chaining for extended reality surgical navigation in visible and near infrared spectrums
US11382699B2 (en) 2020-02-10 2022-07-12 Globus Medical Inc. Extended reality visualization of optical tool tracking volume for computer assisted navigation in surgery
US11207150B2 (en) 2020-02-19 2021-12-28 Globus Medical, Inc. Displaying a virtual model of a planned instrument attachment to ensure correct selection of physical instrument attachment
US11690697B2 (en) 2020-02-19 2023-07-04 Globus Medical, Inc. Displaying a virtual model of a planned instrument attachment to ensure correct selection of physical instrument attachment
US11253216B2 (en) 2020-04-28 2022-02-22 Globus Medical Inc. Fixtures for fluoroscopic imaging systems and related navigation systems and methods
US11510750B2 (en) 2020-05-08 2022-11-29 Globus Medical, Inc. Leveraging two-dimensional digital imaging and communication in medicine imagery in three-dimensional extended reality applications
US11153555B1 (en) 2020-05-08 2021-10-19 Globus Medical Inc. Extended reality headset camera system for computer assisted navigation in surgery
US11382700B2 (en) 2020-05-08 2022-07-12 Globus Medical Inc. Extended reality headset tool tracking and control
US11839435B2 (en) 2020-05-08 2023-12-12 Globus Medical, Inc. Extended reality headset tool tracking and control
US11838493B2 (en) 2020-05-08 2023-12-05 Globus Medical Inc. Extended reality headset camera system for computer assisted navigation in surgery
US11317973B2 (en) 2020-06-09 2022-05-03 Globus Medical, Inc. Camera tracking bar for computer assisted navigation during surgery
US11382713B2 (en) 2020-06-16 2022-07-12 Globus Medical, Inc. Navigated surgical system with eye to XR headset display calibration
US11877807B2 (en) 2020-07-10 2024-01-23 Globus Medical, Inc Instruments for navigated orthopedic surgeries
US11793588B2 (en) 2020-07-23 2023-10-24 Globus Medical, Inc. Sterile draping of robotic arms
US11737831B2 (en) 2020-09-02 2023-08-29 Globus Medical Inc. Surgical object tracking template generation for computer assisted navigation during surgical procedure
US11523785B2 (en) 2020-09-24 2022-12-13 Globus Medical, Inc. Increased cone beam computed tomography volume length without requiring stitching or longitudinal C-arm movement
US11890122B2 (en) 2020-09-24 2024-02-06 Globus Medical, Inc. Increased cone beam computed tomography volume length without requiring stitching or longitudinal c-arm movement
US11911112B2 (en) 2020-10-27 2024-02-27 Globus Medical, Inc. Robotic navigational system
US11941814B2 (en) 2020-11-04 2024-03-26 Globus Medical Inc. Auto segmentation using 2-D images taken during 3-D imaging spin
US11717350B2 (en) 2020-11-24 2023-08-08 Globus Medical Inc. Methods for robotic assistance and navigation in spinal surgery and related systems
US11857273B2 (en) 2021-07-06 2024-01-02 Globus Medical, Inc. Ultrasonic robotic surgical navigation
US11850009B2 (en) 2021-07-06 2023-12-26 Globus Medical, Inc. Ultrasonic robotic surgical navigation
US11439444B1 (en) 2021-07-22 2022-09-13 Globus Medical, Inc. Screw tower and rod reduction tool
US11622794B2 (en) 2021-07-22 2023-04-11 Globus Medical, Inc. Screw tower and rod reduction tool
US11918304B2 (en) 2021-12-20 2024-03-05 Globus Medical, Inc Flat panel registration fixture and method of using same
US11911115B2 (en) 2021-12-20 2024-02-27 Globus Medical Inc. Flat panel registration fixture and method of using same
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