US20100249933A1 - Systems and techniques for intravertebral spinal stabilization with expandable devices - Google Patents

Systems and techniques for intravertebral spinal stabilization with expandable devices Download PDF

Info

Publication number
US20100249933A1
US20100249933A1 US12797914 US79791410A US20100249933A1 US 20100249933 A1 US20100249933 A1 US 20100249933A1 US 12797914 US12797914 US 12797914 US 79791410 A US79791410 A US 79791410A US 20100249933 A1 US20100249933 A1 US 20100249933A1
Authority
US
Grant status
Application
Patent type
Prior art keywords
expandable
device
portion
delivery
devices
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US12797914
Inventor
Hai H. Trieu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orthophoenix LLC
Original Assignee
Warsaw Orthopedic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7097Stabilisers comprising fluid filler in an implant, e.g. balloon; devices for inserting or filling such implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/885Tools for expanding or compacting bones or discs or cavities therein
    • A61B17/8852Tools for expanding or compacting bones or discs or cavities therein capable of being assembled or enlarged, or changing shape, inside the bone or disc
    • A61B17/8858Tools for expanding or compacting bones or discs or cavities therein capable of being assembled or enlarged, or changing shape, inside the bone or disc laterally or radially expansible
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4603Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
    • A61F2/4611Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof of spinal prostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00535Surgical instruments, devices or methods, e.g. tourniquets pneumatically or hydraulically operated
    • A61B2017/00557Surgical instruments, devices or methods, e.g. tourniquets pneumatically or hydraulically operated inflatable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/02Surgical instruments, devices or methods, e.g. tourniquets for holding wounds open; Tractors
    • A61B17/025Joint distractors
    • A61B2017/0256Joint distractors for the spine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2817Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2835Bone graft implants for filling a bony defect or an endoprosthesis cavity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006Properties of materials and coating materials
    • A61F2002/30062(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006Properties of materials and coating materials
    • A61F2002/30092Properties of materials and coating materials using shape memory or superelastic materials, e.g. nitinol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/3011Cross-sections or two-dimensional shapes
    • A61F2002/30112Rounded shapes, e.g. with rounded corners
    • A61F2002/30133Rounded shapes, e.g. with rounded corners kidney-shaped or bean-shaped
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/30199Three-dimensional shapes
    • A61F2002/30224Three-dimensional shapes cylindrical
    • A61F2002/30235Three-dimensional shapes cylindrical tubular, e.g. sleeves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/30199Three-dimensional shapes
    • A61F2002/30261Three-dimensional shapes parallelepipedal
    • A61F2002/30271Three-dimensional shapes parallelepipedal hollow parallelepipeds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30317The prosthesis having different structural features at different locations within the same prosthesis
    • A61F2002/30324The prosthesis having different structural features at different locations within the same prosthesis differing in thickness
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30329Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2002/30405Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements made by screwing complementary threads machined on the parts themselves
    • A61F2002/30411Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements made by screwing complementary threads machined on the parts themselves having two threaded end parts connected by a threaded central part with opposite threads at its opposite ends, i.e. for adjusting the distance between both end parts by rotating the central part
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30329Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2002/30428Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements made by inserting a protrusion into a slot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30329Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2002/30518Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements with possibility of relative movement between the prosthetic parts
    • A61F2002/3052Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements with possibility of relative movement between the prosthetic parts unrestrained in only one direction, e.g. moving unidirectionally
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30537Special structural features of bone or joint prostheses not otherwise provided for adjustable
    • A61F2002/3055Special structural features of bone or joint prostheses not otherwise provided for adjustable for adjusting length
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30537Special structural features of bone or joint prostheses not otherwise provided for adjustable
    • A61F2002/30556Special structural features of bone or joint prostheses not otherwise provided for adjustable for adjusting thickness
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30561Special structural features of bone or joint prostheses not otherwise provided for breakable or frangible
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30581Special structural features of bone or joint prostheses not otherwise provided for having a pocket filled with fluid, e.g. liquid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30581Special structural features of bone or joint prostheses not otherwise provided for having a pocket filled with fluid, e.g. liquid
    • A61F2002/30583Special structural features of bone or joint prostheses not otherwise provided for having a pocket filled with fluid, e.g. liquid filled with hardenable fluid, e.g. curable in-situ
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30581Special structural features of bone or joint prostheses not otherwise provided for having a pocket filled with fluid, e.g. liquid
    • A61F2002/30584Special structural features of bone or joint prostheses not otherwise provided for having a pocket filled with fluid, e.g. liquid filled with gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30621Features concering the anatomical functioning or articulation of the prosthetic joint
    • A61F2002/30624Hinged joint, e.g. with transverse axle restricting the movement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30667Features concerning an interaction with the environment or a particular use of the prosthesis
    • A61F2002/30677Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external and/or bone-contacting surfaces, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external and/or bone-contacting surfaces, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes, grooves
    • A61F2002/30772Apertures or holes, e.g. of circular cross section
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external and/or bone-contacting surfaces, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external and/or bone-contacting surfaces, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes, grooves
    • A61F2002/30841Sharp anchoring protrusions for impaction into the bone, e.g. sharp pins, spikes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external and/or bone-contacting surfaces, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external and/or bone-contacting surfaces, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes, grooves
    • A61F2002/30878Special external and/or bone-contacting surfaces, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes, grooves with non-sharp protrusions, for instance contacting the bone for anchoring, e.g. keels, pegs, pins, posts, shanks, stems, struts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2002/4475Joints for the spine, e.g. vertebrae, spinal discs hollow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2002/448Joints for the spine, e.g. vertebrae, spinal discs comprising multiple adjacent spinal implants within the same intervertebral space or within the same vertebra, e.g. comprising two adjacent spinal implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4603Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
    • A61F2002/4625Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use
    • A61F2002/4627Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use with linear motion along or rotating motion about the instrument axis or the implantation direction, e.g. telescopic, along a guiding rod, screwing inside the instrument
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4603Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
    • A61F2002/4625Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use
    • A61F2002/4628Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use with linear motion along or rotating motion about an axis transverse to the instrument axis or to the implantation direction, e.g. clamping
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0014Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0085Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof hardenable in situ, e.g. epoxy resins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004Rounded shapes, e.g. with rounded corners
    • A61F2230/0015Kidney-shaped, e.g. bean-shaped
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0069Three-dimensional shapes cylindrical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0082Three-dimensional shapes parallelepipedal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0004Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable
    • A61F2250/0009Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable for adjusting thickness
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0036Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in thickness
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00011Metals or alloys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00179Ceramics or ceramic-like structures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00329Glasses, e.g. bioglass
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00353Bone cement, e.g. polymethylmethacrylate or PMMA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00365Proteins; Polypeptides; Degradation products thereof

Abstract

Expandable devices include a body defining a hollow interior for receiving distal portion of a delivery instrument. The expandable devices are collapsed on the distal portion of the delivery instrument for delivery to the operative site within a vertebral body. Upon delivery of the collapsed expandable devices to the operative site, the distal portion of the delivery instrument is enlargeable to expand the expandable device in situ for implantation at the operative site.

Description

    CROSS-REFERENCE TO RELATED APPLICATION
  • [0001]
    This application claims the benefit of the filing date of Provisional Application Ser. No. 60/428,061 filed on Nov. 21, 2002.
  • BACKGROUND
  • [0002]
    Spinal deformities and injuries can require intravertebral stabilization to restore fractured or deformed vertebral body to a desired condition. Intravertebral stabilization can include the intravertebral insertion and expansion of a balloon to compact cancellous bone tissue and create an intravertebral void. Cement material can then be placed in the intravertebral void. Other techniques include intravertebral placement and expansion of mechanical expansion instruments to reduce vertebral fractures, and the subsequent removal of the instrument followed by placement of bone cement. In either case, post-reduction support of the vertebra can be provided by bone cement placed in a void formed in the vertebral body.
  • [0003]
    Intravertebral reduction with balloons and instruments can result in loss of support for the reduced vertebra when the balloon or instrument is removed to accommodate placement of material in the void created. Further, expansion or enlargement of balloons and expandable instruments in the compressible cancellous bone material can provide inconsistent results since the bone material can influence the direction and degree of expansion. Vertebroplasty techniques which include the injection of bone filler into the vertebral body can require the bone filler to be injected under high pressures with low viscosity, increasing the difficulty in controlling and targeting the filler material into the desired areas within the vertebral body.
  • [0004]
    There remains a need for additional improvements in instruments and techniques for intravertebral spinal stabilization which address these deficiencies, among others.
  • SUMMARY
  • [0005]
    In one aspect, a method for intravertebral reduction, comprises: accessing a vertebral body; forming an access passage into the vertebral body; delivering an expandable device through the passage into the vertebral body in an unexpanded condition; expanding the expandable device in the vertebral body with an expandable element; removing the expandable element; and placing bone filler material within the expanded expandable device.
  • [0006]
    In another aspect, a method for intravertebral reduction, comprises: accessing a vertebral body; forming an access passage into the vertebral body; delivering an expandable device through the passage into the vertebral body in an unexpanded condition; expanding the expandable device with an expandable element in the expandable device to restore a vertebral body height; removing the expandable element; and maintaining the restored vertebral height device with the expanded expandable device.
  • [0007]
    In a further aspect, a system for intravertebral reduction includes a delivery instrument with an expandable element along a distal portion thereof. The system further includes an expandable device including a cavity. The expandable device is removably mountable to the expandable element with the expandable element in the cavity and each of the expandable device and the expandable element in an unexpanded condition. The expandable device is deliverable to an intravertebral space in the unexpanded condition and thereafter expandable with expansion of the expandable element to compress cancellous bone in the intravertebral space.
  • [0008]
    In another aspect, a system for intravertebral reduction includes a delivery instrument with a non-rigid expandable element along a distal portion thereof. The system further includes an expandable device with a cavity between substantially rigid first and second portions. The expandable device is structured for positioning in an intravertebral space. When expandable element is positioned in the cavity it is expandable to move the first and second portions away from one another and compress cancellous bone in the intravertebral space.
  • [0009]
    These and other aspects are also presented in the following description.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • [0010]
    FIG. 1 is a sectional view of a collapsed expandable device and delivery instrument.
  • [0011]
    FIG. 2 is the expandable device and delivery instrument of FIG. 1 in an expanded condition.
  • [0012]
    FIGS. 3 and 4 are a plan view and an elevation view in partial section, respectively, of a spinal column segment having a pair of expandable devices and delivery instruments positioned in an intravertebral space in an unexpanded condition.
  • [0013]
    FIGS. 5 and 6 are a plan view and an elevation view in partial section, respectively, with the expandable devices and delivery instruments of FIGS. 3 and 4 in an expanded condition in the intravertebral space.
  • [0014]
    FIGS. 7 and 8 are a plan view and an elevation view in partial section, respectively, with expanded expandable devices of FIGS. 5 and 6 in the intravertebral space and the delivery instruments removed.
  • [0015]
    FIGS. 9 and 10 are a plan view and an elevation view in partial section, respectively, of a spinal column segment and another embodiment pair of expandable devices and delivery instruments positioned in an intravertebral space in an unexpanded condition.
  • [0016]
    FIGS. 11 and 12 are a plan view and an elevation view in partial section, respectively, with expandable devices and delivery instruments of FIGS. 9 and 10 in an expanded condition in the intravertebral space.
  • [0017]
    FIGS. 13 and 14 are a plan view and an elevation view in partial section, respectively, with the expandable devices of FIGS. 11 and 12 expanded in the intravertebral space and the delivery instruments removed.
  • [0018]
    FIGS. 15 and 16 are a plan view in partial section and an elevation view, respectively, of a spinal column segment having an expandable device and delivery instrument positioned in an intravertebral space in an unexpanded condition.
  • [0019]
    FIGS. 17 and 18 are a plan view in partial section and an elevation view, respectively, with the expandable device and delivery instrument of FIGS. 15 and 16 in an expanded condition in the intravertebral space.
  • [0020]
    FIGS. 19 and 20 are a plan view in partial section and an elevation view, respectively, with the expanded expandable device of FIGS. 17 and 18 in the intravertebral space and the delivery instrument removed.
  • [0021]
    FIG. 21 is an end view of another embodiment expandable device.
  • [0022]
    FIG. 22 is a perspective view of another embodiment expandable device in an unexpanded configuration.
  • [0023]
    FIG. 23 is an elevation view of another embodiment expandable device in an unexpanded configuration.
  • [0024]
    FIG. 24 is an elevation view of the expandable device of FIG. 23 in an expanded configuration.
  • [0025]
    FIG. 25 is an end view of the expanded expandable device of FIG. 24.
  • [0026]
    FIGS. 26A and 26B are a plan view and an elevation view in partial section, respectively, of collapsed expandable devices and delivery instruments according to another embodiment positioned in an intravertebral space of a vertebra.
  • [0027]
    FIGS. 27A and 27B are a plan view and an elevation view in partial section, respectively, with expanded expandable devices and delivery instruments positioned in the intravertebral space and the vertebra reduced.
  • [0028]
    FIGS. 28A and 28B are a plan view and an elevation view in partial section, respectively, with expanded expandable devices in the intravertebral space of the reduced vertebra and the delivery instruments removed.
  • [0029]
    FIGS. 29A and 29B are a plan view and an elevation view in partial section, respectively, of collapsed expandable devices and delivery instruments according to another embodiment positioned in an intravertebral space of a vertebra.
  • [0030]
    FIGS. 30A and 30B are a plan view and an elevation view in partial section, respectively, with expanded expandable devices and delivery instruments in the intraverebral space of and the vertebra reduced.
  • [0031]
    FIGS. 31A and 31B are a plan view and an elevation view in partial section, respectively, with expanded expandable devices in the intravertebral space of the reduced vertebra and the delivery instruments removed.
  • [0032]
    FIGS. 32A and 32B are a plan view and an elevation view in partial section, respectively, of collapsed expandable devices and delivery instruments according to another embodiment positioned in an intravertebral space of a vertebra.
  • [0033]
    FIGS. 33A and 33B are a plan view and an elevation view in partial section, respectively, with expanded expandable devices and delivery instruments in the intravertebral space and the vertebra reduced.
  • [0034]
    FIGS. 34A and 34B are a plan view and an elevation view in partial section, respectively, with expanded expandable devices in the intravertebral space of the reduced vertebra and the delivery instruments removed.
  • [0035]
    FIGS. 35A and 35B are a plan view and an elevation view in partial section, respectively, with a collapsed expandable device and delivery instrument according to another embodiment positioned in an intravertebral space of a vertebra.
  • [0036]
    FIGS. 36A and 36B are a plan view and an elevation view in partial section, respectively, with the expanded expandable device and delivery instrument in the intravertebral space and the vertebra reduced.
  • [0037]
    FIGS. 37A and 37B are a plan view and an elevation view in partial section, respectively, with the expanded expandable device in the intravertebral space of the reduced vertebra and the delivery instrument removed.
  • [0038]
    FIGS. 38A and 38B are a plan view and an elevation view in partial section, respectively, with a collapsed expandable device and delivery instrument according to another embodiment positioned in an intravertebral space of a vertebra.
  • [0039]
    FIGS. 39A and 39B are a plan view and an elevation view in partial section, respectively, with the expanded expandable device and the delivery instrument in the intravertebral space and the vertebra reduced.
  • [0040]
    FIGS. 40A and 40B are a plan view and an elevation view in partial section, respectively, with the expanded expandable device in the intravertebral space of the reduced vertebra and the delivery instrument removed.
  • [0041]
    FIGS. 41A and 41B are elevational views of a delivery instrument with a distal expandable element in an unexpanded condition and expanded condition, respectively.
  • DESCRIPTION OF THE ILLUSTRATED EMBODIMENTS
  • [0042]
    For the purposes of promoting an understanding of the principles of the invention, reference will now be made to the embodiments illustrated in the drawings and specific language will be used to describe the same. It will nevertheless be understood that no limitation of the scope of the invention is thereby intended. Any such alterations and further modifications in the illustrated devices, and any such further applications of the principles of the invention as illustrated herein are contemplated as would normally occur to one skilled in the art to which the invention relates.
  • [0043]
    There are provided systems and methods for positioning and deploying expandable devices in bony structures of a spinal column segment. Such systems can include instruments for delivering the expandable devices to the operative site and expanding the expandable devices in situ. When positioned for intravertebral reduction, the expandable devices provide a substantially rigid interface with the cancellous bone to direction compression forces thereto in a controlled and repeatable manner when the expandable devices are expanded. Such expansion can compress cancellous bone, provide size and/or shape restoration to bony structures, and provide immediate and long-term support of the reduced vertebra.
  • [0044]
    According to one embodiment, the delivery instrument includes a balloon catheter-type instrument having an enlargeable member adjacent a distal portion of the delivery instrument. A collapsed or unexpanded expandable device is positioned about the expandable member and secured thereto for delivery to the operative site in the unexpanded configuration. The delivery instrument can be employed in minimally invasive surgical procedures to deliver the collapsed or unexpanded expandable device to the operative site. Upon positioning the expandable device at the operative site, the distal portion of the delivery instrument is expandable to deploy and expand the expandable device at the operative site. Such deployment and expansion of the expandable device can, for example, compress cancellous bone when deployed in an intravertebral space. The expandable device can provide at least temporary support of the vertebra. Bone filler material can be positioned in a void formed at least partially by the expanded expandable device.
  • [0045]
    Delivery and expansion of the expandable device in the intravertebral space provides mechanical reduction of vertebral fractures or deformities, and post-operative mechanical support for the fractured or deformed vertebral body. Reduction of the vertebral fracture can be targeted by positioning the expandable device in a location where at least one portion of the expandable device can provide a substantially rigid interface with the cancellous bone between the device and the fracture as the device is expanded. The expandable devices can provide at least temporary maintenance of the reduction achieved through expansion while bone filler material is positioned within the expandable device. The expandable device can be provided with one or more openings in its first and second portions, and one or more openings at its proximal and distal ends, to facilitate bony incorporation of the expandable device in the vertebral body.
  • [0046]
    The systems and methods can be employed in minimally invasive surgical approaches to the spine. Such approaches include anterior, posterior, transforaminal, lateral, oblique, transpedicular, extrapedicular, and other approaches to a vertebral body. The approaches can be uni-portal or multi-portal in nature. The approaches can be to any portion of the spinal column segment, including the sacral, lumbar, thoracic, and cervical regions. The systems and methods can be employed with any viewing system to assist in monitoring placement of the expandable devices intravertebrally. Examples of suitable viewing systems include fluoroscopic, endoscopic, microscopic, CT scan, X-ray, and naked eye visualization systems.
  • [0047]
    Referring now to FIGS. 1 and 2, there is shown a first embodiment of an expandable device 30. In this embodiment, expandable device 30 includes an elongated body that includes a first portion 34 positionable toward one endplate of a vertebra and a second portion 44 positionable toward the opposite endplate of the vertebra. First portion 34 extends between a distal leading insertion end 36 and a proximal trailing end 32. Second portion 44 extends between a distal leading insertion end 46 and a proximal trailing end 42. A cavity 40 is defined between first portion 34 and second portion 44. Cavity 40 can extend between and open at distal end 36 and trailing end 32.
  • [0048]
    First portion 34 can be provided with a number of engagement members 38, and second portion 44 can also be provided with a number of engagement members 48. Engagement members 38, 48 can be in the form of teeth, spikes, ridges, threads, barbs, knurlings, protrusions, fins, and combinations thereof, for example. It is further contemplated that the outer surfaces can be smooth, or auxiliary fixation or engagement members can be provided. First and second portions 34, 44 can further include one or more openings 39, 49, respectively, to facilitate bone ingrowth.
  • [0049]
    First portion 34 and second portion 44 are movable away from one another from an unexpanded configuration, as shown in FIG. 1, to an expanded configuration, as shown in FIG. 2. In the unexpanded configuration, expandable device 30 has a height H1 between first portion 34 and second portion 44 as shown in FIG. 1. In the expanded configuration, expandable device 30 has a height H2 between first portion 34 and second portion 44. It is contemplated that height H1 will allow expandable device 30 to be inserted, for example, in a passage drilled into a vertebral body. Height H2 can correspond to a separation distance between first and second portions 34, 44 require to reduce a vertebral fracture or deformity, or provide a desired vertebral body height, for example.
  • [0050]
    A delivery instrument 50 can be provided to move expandable device 30 from its unexpanded configuration to its expanded configuration. Delivery instrument 50 includes a proximal shaft 52 and a distal portion 54 including an expandable element 55. In the illustrated embodiment, expandable element 55 is an inflatable balloon-like structure having a collapsed configuration, as shown in FIG. 1, and an enlarged, inflated configuration, as shown in FIG. 2. Shaft 52 can be provided with a lumen through which fluid or material can be supplied through openings 56 to internal volume 57 of expandable element 55 to enlarge or inflate expandable element 55. Expandable element 55 is positionable in cavity 40 of expandable device 30 with each of the expandable element 55 and expandable device 30 in its unexpanded or collapsed configuration.
  • [0051]
    After delivery of expandable device 30 to the operative site, expandable element 55 can be inflated to provide an enlarged configuration for expandable element 55 and thus separate first and second portions 34, 44 of expandable device 30 as shown in FIG. 2. As expandable device 30 is expanded, first portion 34 and second portion 44 move away from one another and the volume of cavity 40 is increased. This expansion can compress cancellous bone and reduce vertebral fractures and/or restore a vertebral body height when device 30 is positioned intravertebrally.
  • [0052]
    One example of a suitable delivery instrument 50 includes a high-pressure balloon catheter. Shaft 52 can be rigid, semi-rigid, or flexible. Shaft 52 can be fabricated from metals, polymers, or combinations thereof. Shaft 52 can be provided with at least one lumen to allow inflation or enlargement of expandable element 55 with a biocompatible fluid, such as air or saline, for example. Other embodiments contemplate that shaft 52 includes multiple lumens to, for example, deliver bone graft, bone growth material or other suitable bone filler material into the expanded cavity 40 of an expanded device 30. It is contemplated that expandable element 55 is collapsed prior to or simultaneously with placement of the bone filler material.
  • [0053]
    In the illustrated embodiment, distal portion 54 includes a single expandable element, although multiple expandable elements are also contemplated to provide distal portion 54 with alternate enlargement characteristics. For example, distal portion 54 could include a distal expandable element and a proximal expandable element having differing heights to provide angulation between the expanded first and second portions 34, 44 of expandable device 30. In another example, distal portion 54 can include an upper expandable element and a lower expandable element which can be selectively expanded move the adjacent one of first and second portions 34, 44 while the other of the first and second portions remains stationary. In a further example, expandable element 55 expands uni-directionally to move the adjacent one of the first and second portions 34, 44 in the direction of expansion to provide intra-vertebral reduction in a targeted location.
  • [0054]
    In another embodiment, it is contemplated that distal portion 54 can be severed from shaft 52 after expansion, and post-operatively maintain expandable device 30 in an expanded condition. Accordingly, expandable element 55 can be inflated with bone growth material or other suitable bone filler material to facilitate bone growth in an intravertebral space through the expanded device 30. Expandable element 55 can be fabricated from porous material, resorbable material, or other suitable material to allow bone growth through the cavity of the expanded device.
  • [0055]
    Expandable element 55 can include a size and shape that matches the size and shape of cavity 40 in its expanded configuration. In the expanded configuration, expandable element 55 can apply a uniform expansion force along the inner wall surfaces of first portion 34 between leading end 36 and trailing end 32. If configured for bi-directional expansion as shown in FIG. 2, expandable element 55 can apply a uniform expansion force along second portion 44 between leading end 46 and trailing end 42. Expandable element 55 can be provided with any suitable overall shape including conical, frusto-conical, spherical, cubic, spherical, polygonal, ovoid, long conical, long spherical, rectangular, tapered, stepped, dog-bone shape, offset shapes and combinations thereof.
  • [0056]
    Expandable element 55 can be made from any suitable material capable of withstanding the pressure supplied to enlarge or inflate expandable element 55 in situ. Examples include various polymeric materials, including polyethylene, terephthalates, polyolefins, polyurethanes, nylon, polyvinyl chloride, silicone or other suitable material. The material comprising expandable element 55 can be reinforced with woven or non-woven textile materials. Examples of suitable reinforcement materials include those that are polymeric and metallic in nature.
  • [0057]
    Referring now to FIGS. 3 through 8, there is shown an example of a surgical technique employing the expandable devices and delivery instruments for intravertebral repair and/or restoration of a collapsed, pressure fractured or otherwise deformed vertebral body. In FIGS. 3 and 4, there is shown a spinal column segment including a vertebra V1 having an upper endplate E1 and a lower endplate E2. Vertebra V1 has a reduced anterior height configuration H3 as a result of a compression fracture, collapse or other deformity or condition of one or each of the endplates E1, E2 and the vertebral body extending therebetween.
  • [0058]
    Posterior access passages 60, 62 are formed through the pedicles of vertebra V1 to access the interior of vertebral body V1. Passages 60, 62 can be formed by drilling or cutting the bony material of the pedicles to access the interior cancellous bony portion of vertebra V1. Other locations for passages 60, 62 are also contemplated, including extrapedicular approaches to vertebra V1 from a posterior-lateral approach, and also lateral, anterior-lateral, and anterior approaches. It is further contemplated that a single passage can be formed or more than two passages can be formed for any of these approaches.
  • [0059]
    In the illustrated embodiment, a second expandable device 130 and a second delivery instrument 150 are provided for placement through the second passage 62. Expandable device 130 and delivery instrument 150 can be identical to expandable device 30 and delivery instrument 50 discussed above, although such is not required. It is further contemplated that the same delivery instrument 50 can be employed to position the second expandable device 130 after placement and expansion of the first expandable device 30.
  • [0060]
    Unexpanded expandable devices 30, 130 are attached to respective ones of the collapsed distal portions 54, 154 of delivery instruments 50, 150 for delivery to the operative site. It is contemplated that the attachment can be provided by adhesive, frictional or form-fitting interengagement, or mechanical fasteners, for example. Expandable devices 30, 130 are then placed through the respective passages 60, 62 and into the intravertebral space of vertebra V1. A radio-contrast fluid, saline solution, compressed air, or other suitable fluid can be delivered to distal portions 54, 154 through shafts 52, 152 by a syringe or pump operable. The fluid provides sufficient pressure for expansion of expandable elements 55, 155 and thus expand expandable devices 30, 130 as shown in FIGS. 5 and 6. As the pressure and volume of the respective expandable elements 55, 155 increase, the first and second portions of expandable devices 30, 130 are gradually separated and provide an interface that compresses the surrounding cancellous bone to, for example, restore to height H4 a collapsed or fractured vertebra V1.
  • [0061]
    Expandable elements 55, 155 are then deflated or collapsed, and distal portions 54, 154 removed from their respective expanded expandable devices 30, 130 as shown in FIGS. 7 and 8. Expandable devices 30, 130 can be adapted to maintain the desired vertebral height H4 after removal of expandable elements 55, 155 without internal pressure or support being applied to the vertebral body or the expanded devices 30, 130. The expanded devices 30, 130 provide a cavity for placement of bone filler material under low pressures and high viscosity, reducing the time for curing and stabilization to be supplemented with the bone filler material.
  • [0062]
    Bone filler material 64 is then placed in cavity 40 of the expanded expandable device 30, and can also be placed in cavity 140 of expandable device 130. Passages 60, 62 can also be filled with bone filler material 64. Bone filler material 64 can be deposited, packed, or injected into the cavities 40, 140 of expanded expandable devices 30, 130 and/or into the intravertebral space adjacent thereto to provide long term support and stability of vertebra V1 with bone formation.
  • [0063]
    Any suitable osteogenic material or composition is contemplated for the filler material, including autograft, allograft, xenograft, demineralized bone, and synthetic and natural bone graft substitutes, such as bioceramics and polymers, and osteoinductive factors. The terms osteogenic material or osteogenic composition used herein broadly include any material that promotes bone growth or healing including autograft, allograft, xenograft, bone graft substitutes and natural, synthetic and recombinant proteins, hormones and the like.
  • [0064]
    Autograft can be harvested from locations such as the iliac crest using drills, gouges, curettes, and trephines and other tools and methods which are well known to surgeons in this field. Preferably, autograft is harvested from the iliac crest with a minimally invasive donor surgery. The osteogenic material may also include bone reamed away by the surgeon while preparing the endplates.
  • [0065]
    Natural and synthetic graft substitutes which replace the structure or function of bone are also contemplated for the osteogenic composition. Any such graft substitute is contemplated, including for example, demineralized bone matrix, demineralized bone matrix with bone chips, PMMA and other injectable synthetic bone cements, mineral compositions, and bioceramics. A vast array of bioceramic materials, including BIOGLASS®, hydroxyapatite, and calcium phosphate compositions known in the art which can be used to advantage for this purpose. Preferred calcium compositions include bioactive glasses, tricalcium phosphates, and hydroxyapatites. In one embodiment, the graft substitute is a biphasic calcium phosphate ceramic including tricalcium phosphate and hydroxyapatite.
  • [0066]
    In some embodiments, the osteogenic compositions used can comprise a therapeutically effective amount to stimulate or induce bone growth of a bone inductive or growth factor or protein in a pharmaceutically acceptable carrier. Osteoinductive factors that are recombinant human bone morphogenetic proteins (rhBMPs) are contemplated because they are readily available and do not contribute to the spread of infectious diseases. The bone morphogenetic protein can be a rhBMP-2, rhBMP-4 or heterodimers thereof. However, any bone morphogenetic protein is contemplated including bone morphogenetic proteins designated as BMP-1 through BPM-13.
  • [0067]
    The choice of carrier material for the osteogenic composition is based on biocompatibility, biodegradability, mechanical properties, and interface properties as well as the structure of the expandable device. Potential carriers include calcium sulphates, polylactic acids, polyanhydrides, collagen, calcium phosphates, polymeric acrylic esters, and demineralized bone. The carrier may be any suitable carrier capable of delivering the proteins. The carrier can be capable of being eventually resorbed into the body, such as an absorbable collagen sponge marketed by Integra LifeSciences Corporation under the trade name Helistat® Absorbable Collagen Hemostatic Agent. Another carrier is a biphasic calcium phosphate ceramic. Ceramic blocks are commercially available from Sofamor Danek Group, B.P. 4-62180 Rang-du-Fliers, France, and Bioland, 132 Rou d Espangne, 31100 Toulouse, France. The osteoinductive factor is introduced into the carrier in any suitable manner. For example, the carrier may be soaked in a solution containing the factor. One preferred embodiment contemplates use of OSTEOFIL® allograph paste sold by Regeneration Technologies, Inc. The allograph paste can be supplemented with a local autograft obtained from the cutting operation.
  • [0068]
    Referring now to FIGS. 9 through 14, there is shown an example of a surgical technique employing another embodiment expandable device and delivery instrument intravertebrally for repair and/or restoration of a collapsed or pressure fractured vertebral body. In FIGS. 9 and 10, there is shown a spinal column segment including vertebra V1 having upper endplate E1 and lower endplate E2. Vertebra V1 includes a reduced anterior height configuration H3 as a result of a compression fracture, collapse or other deformity or condition of one or each of the endplates E1, E2 and the vertebral body extending therebetween.
  • [0069]
    In FIGS. 9-14, expandable devices 230, 330 are provided that are similar to expandable device 30 discussed above, but include a tapered configuration such that the distal ends 232, 332 can expand or separate a greater distance than proximal ends 234, 334. Accordingly, when positioned in the vertebral body V1 from a posterior approach, distal ends 232, 332 are positionable adjacent the anterior portion of vertebra V1 requiring restoration. Other tapered configurations are also contemplated such as, for example, proximal ends that can expand or separate a greater distance than the distal ends. Such an alternate device could be employed in a vertebra with an anterior fracture in an anterior approach to the vertebra.
  • [0070]
    Delivery instruments 250, 350 can be configured like delivery instrument 50 discussed above, but include one or more expandable elements 255, 355 along distal portions 254, 354 that include a shape adapted to expand the internal cavities 236, 336 of expandable devices 230, 330. Expandable elements 255, 355 can be tapered, stepped or otherwise configured to effect greater expansion at distal ends 232, 332 than at proximal ends 234, 334.
  • [0071]
    Unexpanded expandable devices 230, 330 are attached to collapsed expandable elements 254, 354 of delivery instruments 250, 350 for delivery of expandable devices 230, 330 to the operative site. Expandable devices 230, 330 are then placed through the passages 60, 62 and into the intravertebral space of vertebra V1. A radio-contrast fluid, saline solution, compressed air, or other suitable fluid can be delivered through shafts 252, 352 to expandable elements 255, 355 through a syringe or pump operable to provide sufficient pressure to expand expandable devices 230, 330 as shown in FIGS. 11 and 12. As the pressure and volume of the respective expandable elements 255, 355 increase, expandable devices 230, 330 are gradually expanded and compress the surrounding cancellous bone to restore the collapsed vertebra V1 from height H3 to a desired vertebral body height H4 between endplates E1 and E2.
  • [0072]
    Expandable elements 255, 355 are then deflated or collapsed and removed from their respective expanded expandable devices 230, 330, as shown in FIGS. 13 and 14. Bone filler material 64 can be deposited, packed, or injected into the cavities 236, 336 of the expanded devices 230, 330 to provide long term support and stability of vertebra V1 during bone formation.
  • [0073]
    Intravertebral reduction can also be conducted from other approaches to the vertebral body, such as a lateral approach shown in FIGS. 15-20. A lateral access passage 68 is formed in vertebra V1 to provide assess to the cancellous bony material in the interior of the vertebral body. Expandable device 30 is positioned on distal portion 54 of delivery instrument 50, and delivery instrument 50 is positioned to deliver expandable device 50 into vertebra V1 through lateral access passage 68, as shown in FIGS. 15 and 16. Expandable element 55 is expanded to expand expandable device 30 in vertebra V1, as shown in FIGS. 17 and 18. The expanded expandable device 30 compresses the cancellous bony tissue and restored vertebra V1 to a restored height H4 adjacent at the anterior portion of vertebra V1. In FIGS. 19 and 20, delivery instrument 50 is removed from access passage 68, and bone filler 64 is positioned in the cavity of expandable device 30.
  • [0074]
    In the embodiment of FIGS. 15-20, it is also contemplated that expandable device 30 can be configured to separate a greater distance along the side thereof positioned adjacent the vertebral fracture.
  • [0075]
    The expandable devices contemplated herein can be provided in various forms. For example, as shown in FIG. 21, the first and second portions of the expandable device could be adjustably connected along overlapping sidewalls of the first and second portions. Expandable device 430 includes a first portion 432 and a second portion 442 similar to expandable device 30 discussed above. First portion 432 includes opposite sidewalls 434, 435, and second portion 442 includes opposite sidewalls 444, 445. First portion 432 and second portion 442 define a cavity 438 therebetween into which expandable element 55 of delivery instrument 50 can be positioned.
  • [0076]
    The adjacent sidewalls 434, 444 include a number of interdigitating teeth that engage one another, and the adjacent sidewalls 435, 445 include a number of interdigitating teeth that engage one another. The interdigitating teeth allow first and second portions 432, 442 to be uni-directionally moved away from one another upon expansion of expandable element 55 in cavity 438 as indicated by arrows 440. The interdigitating teeth can include a ratcheted configuration that resists or prevents movement of first and second portions 432, 442 toward one another after expansion. Expandable device 430 maintains support of the reduced vertebra immediately after reduction, even after removal of expandable element 55 from cavity 438. The interdigitating teeth further define a number of expanded or separated positions between first and second portions 432, 442 that provide various reduction heights that can be effected with a single expandable device 430.
  • [0077]
    In another example, the expandable devices could be made from a shape memory material or ductile that is unexpanded or collapsed for positioning on the delivery instrument prior to insertion. Upon insertion to the surgical location, the device is radially expandable with inflation or enlargement of the delivery instrument to assume an expanded configuration. Expansion of the expandable device can be accomplished with temperature changes, chemical changes, or force induced changes with inflation or enlargement of the enlargeable member 55 of delivery instrument 50.
  • [0078]
    For example, in FIG. 22 there is shown expandable device 530 including a body 538 defining an interior cavity 532 extending between a proximal end 534 and a distal end 536. Body 538 includes a number of portions 542 therearound that each define an elongated flex opening 544. Segments 542 are interconnected by hinges 546. Body 538 is made of sufficiently ductile or formable material such that upon exertion of a radial expansion force, indicated by arrows 540, flex openings 544 can enlarge and hinges 546 can stretch to allow segments 542 to move away from one another, enlarging interior cavity 532.
  • [0079]
    In a further example, the expandable devices can include a first mechanical configuration that allows a collapsed condition for insertion of the device with the delivery instrument. After insertion, the device can be mechanically adjusted upon inflation or enlargement of the distal portion of the delivery instrument to assume an expanded condition at the operative site. Examples of such expandable devices include those made from a wire mesh material, and devices with first and second portion connected by mechanical linkages, as shown in FIGS. 23-25.
  • [0080]
    In FIGS. 23-25 device 630 includes a first portion 632 and a second portion 642. Linkages 650 movably couple first and second portions 632, 642 to one another. Linkages 650 include first and second members 652, 654 pivotally coupled to one another. Members 652, 654 each include a first end positioned in respective ones of the receptacles 634 of first portion 632, and opposite second ends positioned in respective ones of the receptacles 644 of second portion 642. The ends of the members 650, 652 can include a configuration that interdigitates with a ratchet surface formed along the respective receptacles 634, 644. In the unexpanded configuration shown in FIG. 23, the ends of members 652, 654 are positioned at the outer ends of the respective receptacles 634, 644.
  • [0081]
    As first and second portions 632, 642 are uni-directionally moved away from one another with expandable element 55 in cavity 638, as indicated by arrows 640, the ends of members 650, 652 move longitudinally toward one another along the receptacles 634, 644 of each of the respective first and second portions 632, 642, as shown in FIG. 24. The rigid members 652, 654 move first and second portions 632, 642 away from one another, and engage the ratchet surfaces along receptacles 634, 644 to maintain the expanded or separated position between first and second portions 632, 642, as shown in FIGS. 24 and 25.
  • [0082]
    FIGS. 26A and 26B are a plan view and an elevation view in partial section, respectively, of another embodiment pair of collapsed expandable devices 680 and associated delivery instruments 690 positioned in an intravertebral space of vertebra V1. The collapsed or unexpanded expandable devices 680 are secured around the respective unexpanded expandable element 694 at a distal end of delivery instrument 690 for delivery to the intravertebral space. In the illustrated embodiment, vertebra V1 is accessed from a posterior approach through the pedicles, although other approaches are also contemplated. Expandable devices 680 each include a width between opposite sides 686, 688.
  • [0083]
    FIGS. 27A and 27B are a plan view and an elevation view in partial section, respectively, with expandable devices 680 expanded with a fluid delivered through shafts 692 of delivery instruments 690. In the expanded condition, lower and upper surfaces 682, 684 of expandable device 680 compress the surrounding cancellous bone to reduce vertebra V1 from height H3 to a greater restored height H4. The widths between opposite sides 686, 688 of expandable devices 680 remain substantially constant during and after expansion. Accordingly, expandable devices 680 are vertically expandable to increase their height while their widths remain constant, such as shown with expandable devices 430 and 630 discussed above.
  • [0084]
    FIGS. 28A and 28B are a plan view and an elevation view in partial section, respectively, with the expanded expandable devices 680 in the restored vertebra V1 of the spinal column segment and the delivery instruments 690 removed from cavities 685 of expandable devices 680. Filler material for bone growth can be placed in cavities 685 and in approaches 60, 62 as discussed above.
  • [0085]
    FIGS. 29A and 29B are a plan view and an elevation view in partial section, respectively, of another embodiment pair of collapsed expandable devices 700 and associated delivery instruments 710 positioned in vertebra V1. The collapsed or unexpanded expandable devices 700 are secured around the respective unexpanded expandable element 714 at a distal end of delivery instrument 710 for delivery to the intravertebral space. In the illustrated embodiment, the intravertebral space is accessed from a posterior approach through the pedicles, although other approaches are also contemplated. Expandable devices 700 include a width between opposite sides 703, 705.
  • [0086]
    FIGS. 30A and 30B are a plan view and an elevation view in partial section, respectively, with expandable devices 700 expanded with a fluid delivered through shafts 712 of delivery instruments 710. In the expanded condition, lower and upper surfaces 702, 704 of expandable devices 700 compress the surrounding cancellous bone and separate the opposite vertebral endplates to reduce vertebra V1 from height H3 to provide a restored height H4. The widths between opposite sides 703, 705 of expandable devices 700 remain substantially constant during and after expansion. Accordingly, expandable devices 700 are vertically expandable to increase their height while their widths remain constant.
  • [0087]
    Expandable devices 700 are tapered along the length thereof between an anterior end and a posterior end. In the illustrated embodiment, the posterior end includes a first height 708, and the anterior end includes a second height 709 which is greater than first height 708. This tapered height provides a greater reduction of vertebra V1 adjacent the anterior portion thereof, which can be targeted to the region of greatest compression such as provided with an anterior vertebral fracture.
  • [0088]
    FIGS. 31A and 31B are a plan view and an elevation view in partial section, respectively, with the expanded expandable devices 700 in the reduced vertebra V1 of the spinal column segment and the delivery instruments 710 removed from cavities 706 of expandable devices 700. Filler material for bone growth can be placed in cavities 706 and in approaches 60, 62 as discussed above.
  • [0089]
    FIGS. 32A and 32B are a plan view and an elevation view in partial section, respectively, of another embodiment pair of collapsed expandable devices 720 and associated delivery instruments 730 positioned in an intravertebral space of vertebra V1. The collapsed or unexpanded expandable devices 720 are secured around the unexpanded expandable elements 734, 736 at a distal end of delivery instrument 730 for delivery to the intravertebral space. Expandable devices 720 each include a posterior portion 723 and an anterior portion 725, and a width between opposite sides 727, 729. The height and width of expandable devices 720 are substantially uniform in their collapsed or unexpanded condition along portions 723, 725.
  • [0090]
    FIGS. 33A and 33B are a plan view and an elevation view in partial section, respectively, with expandable devices 720 expanded with a fluid delivered through shafts 732 of delivery instruments 730. In the expanded condition, posterior and anterior portions 723, 725 of expandable devices 720 compress cancellous bone and separate the opposite vertebral endplates E1, E2 to reduce vertebra V1 from compressed height H3 to provide a restored vertebral height H4. The width between opposite sides 727, 729 of expandable devices 720 remains substantially constant during and after expansion. Accordingly, expandable devices 720 are vertically expandable while their widths remain constant.
  • [0091]
    Expandable devices 720 are stepped in height between anterior portion 725 and posterior portion 723 to provide a greater anterior height for the expanded expandable devices 720. This stepped height provides a targeted reduction of vertebra V1 anteriorly where, for anterior fractures, the vertebral compression is greatest. To facilitate this stepped and targeted reduction, delivery instrument 730 can be provided with an anterior expandable element 734 and a posterior expandable element 736. Expandable elements 734, 736 can be provided with differing heights in their expanded configurations that conform to the expanded height of respective ones of the anterior and posterior portions 725, 723 in which expandable elements 734, 736 are positioned.
  • [0092]
    FIGS. 34A and 34B are a plan view and an elevation view in partial section, respectively, with the expanded expandable devices 720 in the reduced vertebra V1 of the spinal column segment and the delivery instruments 730 removed from cavities 726 of expandable devices 720. Filler material for bone growth can be placed in cavities 726 and in approaches 60, 62 as discussed above.
  • [0093]
    FIGS. 35A and 35B are a plan view and an elevation view in partial section, respectively, of another embodiment collapsed expandable device 740 and associated delivery instrument 750 positioned in a reduced height vertebra V1. The collapsed or unexpanded expandable device 740 is secured around the unexpanded expandable element 754 at a distal end of delivery instrument 750 for delivery to the reduced height vertebra V1. Expandable device 740 includes, in the collapsed condition, a convexly curved anterior wall 742 and a concavely curved posterior wall 744. Walls 742, 744 form a banana or kidney shape that facilitates placement of expandable device 740 in the intravertebral space for bi-lateral support of endplates E1, E2 of vertebra V1 from a single uni-lateral approach 60. Accordingly, the invasiveness of the procedure is even further reduced.
  • [0094]
    FIGS. 36A and 36B are a plan view and an elevation view in partial section, respectively, with expandable device 740 expanded with a fluid delivered through shaft 752 of delivery instrument 750. In the expanded condition, upper and lower portions 747, 748 of expandable device 740 compress the surrounding cancellous bone and separate the opposite vertebral endplates E1, E2 to reduce vertebra V1 to a restored height H4. Expansion of expandable device 740 can result in posterior wall 744 moving posteriorly such that in the expanded condition, posterior wall 744 is substantially linear to provide expandable device 740 with a D shape.
  • [0095]
    Expandable device 740 includes convexly curved anterior wall 742 which facilitates placement of expandable device 740 along a curved insertion path from approach 60 in which the anterior wall 742 conforms to the profile of the curved anterior portion of vertebra V1. In the illustrated embodiment, expandable device 740 is positioned in the anterior half of vertebra V1. Expandable element 754 can be provided with a shape that conforms to the D-shaped interior cavity 746 when expanded.
  • [0096]
    FIGS. 37A and 37B are a plan view and an elevation view in partial section, respectively, with the expanded expandable device 740 in the restored vertebra V1 of the spinal column segment and the delivery instrument 750 removed from cavity 746 of expandable device 740. Filler material for bone growth can be placed in cavity 746 and in approach 60 as discussed above.
  • [0097]
    FIGS. 38A and 38B are a plan view and an elevation view in partial section, respectively, of another embodiment collapsed expandable device 760 and associated delivery instrument 770 positioned in a reduced height vertebra V1. The collapsed or unexpanded expandable device 760 is secured around the unexpanded expandable element 774 at a distal end of delivery instrument 770 for delivery to the intravertebral space from lateral approach 68. Expandable device 760 includes a first portion 762 and a second portion 764 engaged along opposite sides of expandable element 774 and positionable toward respective ones of the endplates E1 and E2.
  • [0098]
    FIGS. 39A and 39B are a plan view and an elevation view in partial section, respectively, with expandable device 760 expanded by manipulating shaft 772 of delivery instrument 770 to expand expandable element 774. In the expanded condition, first and second portions 762, 764 of expandable device 760 compress the adjacent cancellous bone and separate opposite vertebral endplates E1, E2 to reduce vertebra V1 and provide a restored height H4.
  • [0099]
    FIGS. 40A and 40B are a plan view and an elevation view in partial section, respectively, with the expanded expandable device 760 in the restored vertebra V1 of the spinal column segment and the delivery instrument 770 removed from cavity 766 of expandable device 760. Filler material for bone growth can be placed in cavity 766 and in approach 68 as discussed above.
  • [0100]
    Further details of delivery instrument 770 are provided in FIGS. 41A and 41B. Shaft 772 includes a proximal handle portion 773 and a distal portion 776 extending through expandable element 774. Expandable element 774 includes a first pivoting linkage 778 and a second pivoting linkage 780. Linkages 778, 780 each include an intermediate pivot point engaged to and movable with distal portion 776. Linkages 778, 780 further include reduction members 782, 784 coupled at the upper and lower ends thereof.
  • [0101]
    Distal portion 776 is coupled to linkages 778, 780 so that, as shaft 772 is rotated about its axis with handle portion 773 as indicated in FIG. 41A, the pivoting intermediate portions of linkages 778, 780 are drawn toward one another to move reduction members 782, 784 away from one another, as shown in FIG. 41B. When positioned in a cavity of an expandable device, reduction members 782, 784 contact adjacent portions of the expandable device to expand the expandable device and reduce the vertebra. When the desired reduction has been achieved, expandable device 770 can be removed from the expandable device by rotating shaft 772 in the opposite direction and move reduction members 782, 784 toward one another.
  • [0102]
    The expandable devices herein can be provided with one or more openings, windows or other structure that allows communication between the interior cavity thereof and the adjacent bony tissue to facilitate bone ingrowth. The expandable devices can include a single cavity or multiple cavities. It is further contemplated that the expandable devices could be provided with support mechanisms positionable in the cavity to maintain or assist in maintaining an expanded condition of the device.
  • [0103]
    The expandable devices discussed herein can be made from any bio-compatible material, including metals, polymers and composites. Examples of metals include titanium and titanium alloys; nickel titanium alloys; stainless steel; and cobalt chrome alloys. Examples of polymers include polyaryletherketone; polyetherethereketone; polysulfone; polyolefin; polyethylene; tyrosine-based polycarbonate; polyester; polylactide; polyglicolide; polyorthoester; polyphosphazene; polyhydroxylbutyrate; and polyhydroxylvalerate, for example. Examples of composites include carbon filled composites; hydroxy-apetite filled composites; bioactive glass filled composites; and cortical bone chip filled composites, for example.
  • [0104]
    While the invention has been illustrated and described in detail in the drawings and foregoing description, the same is to be considered as illustrative and not restrictive in character. All changes and modifications that come within the spirit of the invention are desired to be protected.

Claims (21)

  1. 1-67. (canceled)
  2. 68. An intravertebral treatment device comprising:
    a first portion configured for engagement with a vertebra toward a first endplate of the vertebra;
    a second portion configured for engagement with the vertebra toward a second endplate of the vertebra; and
    a linkage connecting the first portion and the second portion, the linkage being configured to facilitate relative movement of the first portion and the second portion between a collapsed configuration and an expanded configuration.
  3. 69. The intravertebral treatment device according to claim 68, further comprising a detachable shaft disposed with the linkage in a configuration to facilitate relative movement of the first portion and the second portion between the collapsed configuration and the expanded configuration.
  4. 70. The intravertebral treatment device according to claim 68, wherein the linkage includes a proximal portion and a distal portion, the proximal portion and the distal portion being configured to move toward one another as the first portion and the second portion move to the expanded configuration.
  5. 71. The intravertebral treatment device according to claim 68, further comprising a shaft coupled with the linkage in a configuration to facilitate relative movement of the first portion and the second portion between the collapsed configuration and the expanded configuration.
  6. 72. The intravertebral treatment device according to claim 68, wherein the linkage includes a first pivoting linkage and a second pivoting linkage, the first and second linkages being connected to the first portion and the first and second linkages being connected to the second portion.
  7. 73. The intravertebral treatment device according to claim 72, wherein the first pivoting linkage includes a first pivot point and the second pivoting linkage includes a second pivot point, the first pivot point and the second pivot point being drawn together to move the first portion and the second portion to the expanded configuration.
  8. 74. The intravertebral treatment device according to claim 73, further comprising a shaft coupled to the first pivoting linkage and the second pivoting linkage, wherein the first pivot point and the second pivot point are drawn together by rotation of the shaft.
  9. 75. The intravertebral treatment device according to claim 68, wherein the first portion and the second portion are selectively movable via the linkage to a plurality of fixed orientations between the collapsed configuration and the expanded configuration.
  10. 76. The intravertebral treatment device according to claim 68, wherein the first portion and the second portion are substantially flat.
  11. 77. The intravertebral treatment device according to claim 68, wherein the first portion and the second portion define a cavity therebetween configured for disposal of a filler material.
  12. 78. An intravertebral treatment device comprising:
    a body including a first portion and a second portion, the first portion defining an engagement surface configured for engagement with a vertebra toward a first endplate of the vertebra, the second portion defining an engagement surface configured for engagement with the vertebra toward a second endplate of the vertebra, the first portion and the second portion defining a cavity therebetween configured for disposal of a filler material;
    a linkage connecting the first portion and the second portion; and
    a shaft coupled with the linkage in a configuration to facilitate relative movement of the first portion and the second portion between the collapsed configuration and the expanded configuration in an orientation to provide reduction and stabilization of the vertebra.
  13. 79. An intravertebral treatment device according to claim 78, wherein the linkage includes a proximal portion and a distal portion, the proximal portion and the distal portion being configured to move toward one another as the first portion and the second portion move to the expanded configuration.
  14. 80. The intravertebral treatment device according to claim 78, wherein the linkage includes a first pivoting linkage and a second pivoting linkage, the first and second linkages being connected to the first portion and the first and second linkages being connected to the second portion.
  15. 81. The intravertebral treatment device according to claim 80, wherein the first pivoting linkage includes a first pivot point and the second pivoting linkage includes a second pivot point, the first pivot point and the second pivot point being drawn together to move the first portion and the second portion to the expanded configuration.
  16. 82. The intravertebral treatment device according to claim 81, wherein the first pivot point and the second pivot point are drawn together by rotation of the shaft.
  17. 83. The intravertebral treatment device according to claim 82, wherein the first pivot joint and the second pivot joint are moved apart to move the first portion and the second portion toward one another,
    wherein the first pivot joint and the second pivot joint are drawn together by rotation of the shaft in a first direction, and
    wherein the first pivot joint and the second pivot joint are moved apart by rotation of the shaft in a second direction opposite to the first direction.
  18. 84. The intravertebral treatment device according to claim 78, further comprising a bone filler material disposed between the first portion and the second portion.
  19. 85. A method for treating a vertebral body, the method comprising:
    providing an expandable device comprising a first reduction member, a second reduction member, a linkage coupled between the first reduction member and the second reduction member, and a shaft coupled to the linkage;
    placing the expandable device into the vertebral body;
    rotating the shaft to cause the linkage to move the first reduction member and the second reduction member away from one another.
  20. 86. The method of claim 85, wherein moving the first reduction member and the second reduction member away from one another reduces the vertebral body.
  21. 87. The method of claim 85, wherein moving the first reduction member and the second reduction member away from one another creates a cavity in the vertebral body,
    the method further comprising placing a filler material in the cavity.
US12797914 2002-11-21 2010-06-10 Systems and techniques for intravertebral spinal stabilization with expandable devices Abandoned US20100249933A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US42806102 true 2002-11-21 2002-11-21
US10717693 US7758644B2 (en) 2002-11-21 2003-11-20 Systems and techniques for intravertebral spinal stabilization with expandable devices
US12797914 US20100249933A1 (en) 2002-11-21 2010-06-10 Systems and techniques for intravertebral spinal stabilization with expandable devices

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12797914 US20100249933A1 (en) 2002-11-21 2010-06-10 Systems and techniques for intravertebral spinal stabilization with expandable devices

Publications (1)

Publication Number Publication Date
US20100249933A1 true true US20100249933A1 (en) 2010-09-30

Family

ID=39561999

Family Applications (2)

Application Number Title Priority Date Filing Date
US10717693 Active 2027-03-06 US7758644B2 (en) 2002-11-21 2003-11-20 Systems and techniques for intravertebral spinal stabilization with expandable devices
US12797914 Abandoned US20100249933A1 (en) 2002-11-21 2010-06-10 Systems and techniques for intravertebral spinal stabilization with expandable devices

Family Applications Before (1)

Application Number Title Priority Date Filing Date
US10717693 Active 2027-03-06 US7758644B2 (en) 2002-11-21 2003-11-20 Systems and techniques for intravertebral spinal stabilization with expandable devices

Country Status (2)

Country Link
US (2) US7758644B2 (en)
WO (1) WO2004047689A1 (en)

Cited By (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100063595A1 (en) * 2004-11-24 2010-03-11 Dietz Terry L Adjustable knee tibial trial insert
US20100064045A1 (en) * 2007-05-10 2010-03-11 Teliasonera Ab Handing a request relating to a service
US20110093074A1 (en) * 2009-10-15 2011-04-21 Chad Glerum Expandable Fusion Device and Method of Installation Thereof
US20110213402A1 (en) * 2005-05-24 2011-09-01 Kyphon Sarl Low-compliance expandable medical device
US20130116791A1 (en) * 2011-11-04 2013-05-09 Boo Holdings, Llc Expandable intervertebral spacer implant
US8518120B2 (en) 2009-10-15 2013-08-27 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US8518114B2 (en) 2011-04-21 2013-08-27 Warsaw Orthopedic, Inc. Expandable implant system and methods of use
US8556979B2 (en) 2009-10-15 2013-10-15 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US8685098B2 (en) 2010-06-25 2014-04-01 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US8709086B2 (en) 2009-10-15 2014-04-29 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US8771277B2 (en) 2012-05-08 2014-07-08 Globus Medical, Inc Device and a method for implanting a spinous process fixation device
US8845728B1 (en) 2011-09-23 2014-09-30 Samy Abdou Spinal fixation devices and methods of use
US8845734B2 (en) 2010-09-03 2014-09-30 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US8845731B2 (en) 2010-09-03 2014-09-30 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US8852279B2 (en) 2010-09-03 2014-10-07 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US8864833B2 (en) 2011-09-30 2014-10-21 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US8876866B2 (en) 2010-12-13 2014-11-04 Globus Medical, Inc. Spinous process fusion devices and methods thereof
US8998992B2 (en) 2008-08-29 2015-04-07 Globus Medical, Inc. Devices and methods for treating bone
US9011493B2 (en) 2012-12-31 2015-04-21 Globus Medical, Inc. Spinous process fixation system and methods thereof
US9034045B2 (en) 2013-03-15 2015-05-19 Globus Medical, Inc Expandable intervertebral implant
US9125757B2 (en) 2010-09-03 2015-09-08 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US9149367B2 (en) 2013-03-15 2015-10-06 Globus Medical Inc Expandable intervertebral implant
US9186258B2 (en) 2013-03-15 2015-11-17 Globus Medical, Inc. Expandable intervertebral implant
US9198697B2 (en) 2013-03-13 2015-12-01 Globus Medical, Inc. Spinous process fixation system and methods thereof
US9204972B2 (en) 2013-03-01 2015-12-08 Globus Medical, Inc. Articulating expandable intervertebral implant
US9351848B2 (en) 2010-09-03 2016-05-31 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US9370434B2 (en) 2010-09-03 2016-06-21 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US9402739B2 (en) 2014-02-07 2016-08-02 Globus Medical, Inc. Variable lordosis spacer and related methods of use
US9402738B2 (en) 2013-02-14 2016-08-02 Globus Medical, Inc. Devices and methods for correcting vertebral misalignment
US9474625B2 (en) 2010-09-03 2016-10-25 Globus Medical, Inc Expandable fusion device and method of installation thereof
US9486251B2 (en) 2012-12-31 2016-11-08 Globus Medical, Inc. Spinous process fixation system and methods thereof
US9566168B2 (en) 2010-09-03 2017-02-14 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US9585765B2 (en) 2013-02-14 2017-03-07 Globus Medical, Inc Devices and methods for correcting vertebral misalignment
US9597200B2 (en) 2010-06-25 2017-03-21 Globus Medical, Inc Expandable fusion device and method of installation thereof
US9707100B2 (en) 2015-06-25 2017-07-18 Institute for Musculoskeletal Science and Education, Ltd. Interbody fusion device and system for implantation
US9782265B2 (en) 2013-02-15 2017-10-10 Globus Medical, Inc Articulating and expandable vertebral implant
US9788971B1 (en) 2013-05-22 2017-10-17 Nuvasive, Inc. Expandable fusion implant and related methods
US9801734B1 (en) 2013-08-09 2017-10-31 Nuvasive, Inc. Lordotic expandable interbody implant
US9855151B2 (en) 2010-09-03 2018-01-02 Globus Medical, Inc Expandable fusion device and method of installation thereof

Families Citing this family (227)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080086212A1 (en) 1997-01-02 2008-04-10 St. Francis Medical Technologies, Inc. Spine distraction implant
US8128661B2 (en) 1997-01-02 2012-03-06 Kyphon Sarl Interspinous process distraction system and method with positionable wing and method
US20080215058A1 (en) 1997-01-02 2008-09-04 Zucherman James F Spine distraction implant and method
US6068630A (en) 1997-01-02 2000-05-30 St. Francis Medical Technologies, Inc. Spine distraction implant
US7201751B2 (en) 1997-01-02 2007-04-10 St. Francis Medical Technologies, Inc. Supplemental spine fixation device
US20050228397A1 (en) * 1998-08-14 2005-10-13 Malandain Hugues F Cavity filling device
CA2363254C (en) 1999-03-07 2009-05-05 Discure Ltd. Method and apparatus for computerized surgery
US6805695B2 (en) 2000-04-04 2004-10-19 Spinalabs, Llc Devices and methods for annular repair of intervertebral discs
US6969610B2 (en) * 2001-01-12 2005-11-29 University Of Rochester Methods of modifying cell structure and remodeling tissue
US6632235B2 (en) 2001-04-19 2003-10-14 Synthes (U.S.A.) Inflatable device and method for reducing fractures in bone and in treating the spine
DE10154163A1 (en) 2001-11-03 2003-05-22 Advanced Med Tech An apparatus for raising and stabilizing the spine
US8317798B2 (en) * 2002-06-25 2012-11-27 Warsaw Orthopedic Minimally invasive expanding spacer and method
FR2844179B1 (en) 2002-09-10 2004-12-03 Jean Taylor support assembly posterior vertebral
US20080021468A1 (en) 2002-10-29 2008-01-24 Zucherman James F Interspinous process implants and methods of use
US7306628B2 (en) 2002-10-29 2007-12-11 St. Francis Medical Technologies Interspinous process apparatus and method with a selectably expandable spacer
CA2735334A1 (en) * 2002-11-05 2004-05-21 Spineology, Inc. A semi-biological intervertebral disc replacement system
WO2004047689A1 (en) * 2002-11-21 2004-06-10 Sdgi Holdings, Inc. Systems and techniques for intravertebral spinal stablization with expandable devices
DE602004018903D1 (en) 2003-02-14 2009-02-26 Depuy Spine Inc intervertebral fusion device prepared in situ
US20050010297A1 (en) * 2003-05-08 2005-01-13 Kuros Biosurgery Ag Balloon technologies for tissue repair
US7175628B2 (en) 2003-05-21 2007-02-13 Crosstrees Medical, Inc. Extractable filler for inserting medicine into animal tissue
US7175627B2 (en) * 2003-05-21 2007-02-13 Crosstrees Medical, Inc. Extractable filler for inserting medicine into animal tissue
US8048117B2 (en) 2003-05-22 2011-11-01 Kyphon Sarl Interspinous process implant and method of implantation
US8070778B2 (en) 2003-05-22 2011-12-06 Kyphon Sarl Interspinous process implant with slide-in distraction piece and method of implantation
US7549999B2 (en) 2003-05-22 2009-06-23 Kyphon Sarl Interspinous process distraction implant and method of implantation
US7799082B2 (en) 2003-08-05 2010-09-21 Flexuspine, Inc. Artificial functional spinal unit system and method for use
US7909869B2 (en) 2003-08-05 2011-03-22 Flexuspine, Inc. Artificial spinal unit assemblies
US8118869B2 (en) 2006-03-08 2012-02-21 Flexuspine, Inc. Dynamic interbody device
US7753958B2 (en) 2003-08-05 2010-07-13 Gordon Charles R Expandable intervertebral implant
US7175629B2 (en) * 2003-09-29 2007-02-13 Crosstrees Medical, Inc. Extractable filler for inserting medicine into vertebral body
US7655010B2 (en) * 2003-09-30 2010-02-02 Depuy Spine, Inc. Vertebral fusion device and method for using same
US20050187556A1 (en) * 2004-02-25 2005-08-25 Synecor, Llc Universal percutaneous spinal access system
US7959634B2 (en) * 2004-03-29 2011-06-14 Soteira Inc. Orthopedic surgery access devices
US7465318B2 (en) 2004-04-15 2008-12-16 Soteira, Inc. Cement-directing orthopedic implants
US7585316B2 (en) 2004-05-21 2009-09-08 Warsaw Orthopedic, Inc. Interspinous spacer
US8142462B2 (en) 2004-05-28 2012-03-27 Cavitech, Llc Instruments and methods for reducing and stabilizing bone fractures
US7887587B2 (en) * 2004-06-04 2011-02-15 Synthes Usa, Llc Soft tissue spacer
FR2871366A1 (en) * 2004-06-09 2005-12-16 Ceravic Soc Par Actions Simpli expandable prosthetic bone implant
FR2871679A1 (en) * 2004-06-18 2005-12-23 Charles Abulker Percutaneous vertebral implant, useful for straightening collapsed disks and consolidating damaged intervertebral spaces, comprises balloon open at one end for threading on a carrier
EP1623727A1 (en) 2004-07-14 2006-02-08 Bruno Sidler Fller and administration device for forming a supportive structure in a bone cavity
EP1793769A4 (en) * 2004-09-02 2009-06-24 Crosstrees Medical Inc Device and method for distraction of the spinal disc space
US8597360B2 (en) * 2004-11-03 2013-12-03 Neuropro Technologies, Inc. Bone fusion device
US7799078B2 (en) * 2004-11-12 2010-09-21 Warsaw Orthopedic, Inc. Implantable vertebral lift
EP1827244A2 (en) * 2004-11-22 2007-09-05 Endius Incorporated Expandable device for providing access to the spine
US20060167547A1 (en) * 2005-01-21 2006-07-27 Loubert Suddaby Expandable intervertebral fusion implants having hinged sidewalls
US20060184192A1 (en) * 2005-02-11 2006-08-17 Markworth Aaron D Systems and methods for providing cavities in interior body regions
US8057513B2 (en) 2005-02-17 2011-11-15 Kyphon Sarl Percutaneous spinal implants and methods
US7988709B2 (en) 2005-02-17 2011-08-02 Kyphon Sarl Percutaneous spinal implants and methods
US8157841B2 (en) 2005-02-17 2012-04-17 Kyphon Sarl Percutaneous spinal implants and methods
US8029567B2 (en) 2005-02-17 2011-10-04 Kyphon Sarl Percutaneous spinal implants and methods
US8096994B2 (en) 2005-02-17 2012-01-17 Kyphon Sarl Percutaneous spinal implants and methods
US7998174B2 (en) 2005-02-17 2011-08-16 Kyphon Sarl Percutaneous spinal implants and methods
US8097018B2 (en) 2005-02-17 2012-01-17 Kyphon Sarl Percutaneous spinal implants and methods
US8100943B2 (en) 2005-02-17 2012-01-24 Kyphon Sarl Percutaneous spinal implants and methods
US8007521B2 (en) 2005-02-17 2011-08-30 Kyphon Sarl Percutaneous spinal implants and methods
US20070276493A1 (en) 2005-02-17 2007-11-29 Malandain Hugues F Percutaneous spinal implants and methods
US8038698B2 (en) 2005-02-17 2011-10-18 Kphon Sarl Percutaneous spinal implants and methods
US8034080B2 (en) 2005-02-17 2011-10-11 Kyphon Sarl Percutaneous spinal implants and methods
US7749252B2 (en) 2005-03-21 2010-07-06 Kyphon Sarl Interspinous process implant having deployable wing and method of implantation
US8147548B2 (en) 2005-03-21 2012-04-03 Kyphon Sarl Interspinous process implant having a thread-shaped wing and method of implantation
US7731751B2 (en) * 2005-03-31 2010-06-08 Life Spine, Inc. Expandable spinal devices and method of insertion
US20060235423A1 (en) * 2005-04-01 2006-10-19 Cantu Alberto R Apparatus having at least one actuatable planar surface and method using the same for a spinal procedure
US8034079B2 (en) 2005-04-12 2011-10-11 Warsaw Orthopedic, Inc. Implants and methods for posterior dynamic stabilization of a spinal motion segment
US7959652B2 (en) 2005-04-18 2011-06-14 Kyphon Sarl Interspinous process implant having deployable wings and method of implantation
JP5112295B2 (en) * 2005-04-27 2013-01-09 スタウト メディカル グループ,エル.ピー. Expandable support device and methods of use thereof
US7727233B2 (en) 2005-04-29 2010-06-01 Warsaw Orthopedic, Inc. Spinous process stabilization devices and methods
US7632313B2 (en) 2005-04-29 2009-12-15 Jmea Corporation Disc repair system
US8702718B2 (en) 2005-04-29 2014-04-22 Jmea Corporation Implantation system for tissue repair
US7608108B2 (en) * 2005-04-29 2009-10-27 Jmea Corporation Tissue repair system
US8187327B2 (en) * 2005-05-18 2012-05-29 Kyphon Sarl Selectively-expandable bone scaffold
EP1956990A2 (en) * 2005-12-08 2008-08-20 Synthes GmbH Apparatus and methods for treating bone
US20070093899A1 (en) * 2005-09-28 2007-04-26 Christof Dutoit Apparatus and methods for treating bone
US8080061B2 (en) * 2005-06-20 2011-12-20 Synthes Usa, Llc Apparatus and methods for treating bone
FR2887434B1 (en) 2005-06-28 2008-03-28 Jean Taylor Surgical treatment equipment two vertebrae
JP4907908B2 (en) * 2005-06-29 2012-04-04 ルネサスエレクトロニクス株式会社 Driving circuit and a display device
KR20080047357A (en) * 2005-07-07 2008-05-28 크로스트리스 메디칼, 인코포레이티드 Devices and methods for the treatment of bone fracture
EP1909658A2 (en) * 2005-07-11 2008-04-16 Kyphon Inc. Systems and methods for providing cavities in interior body regions
US20070055276A1 (en) * 2005-07-11 2007-03-08 Edidin Avram A Systems and methods for inserting biocompatible filler materials in interior body regions
US20070010848A1 (en) * 2005-07-11 2007-01-11 Andrea Leung Systems and methods for providing cavities in interior body regions
US7785368B2 (en) 2005-08-16 2010-08-31 Benvenue Medical, Inc. Spinal tissue distraction devices
US8366773B2 (en) 2005-08-16 2013-02-05 Benvenue Medical, Inc. Apparatus and method for treating bone
US20070067034A1 (en) * 2005-08-31 2007-03-22 Chirico Paul E Implantable devices and methods for treating micro-architecture deterioration of bone tissue
US8603098B2 (en) * 2005-09-12 2013-12-10 K2M, Inc. Posterior modular disc replacement system
US20070093822A1 (en) 2005-09-28 2007-04-26 Christof Dutoit Apparatus and methods for vertebral augmentation using linked expandable bodies
US20070088436A1 (en) * 2005-09-29 2007-04-19 Matthew Parsons Methods and devices for stenting or tamping a fractured vertebral body
US8157806B2 (en) 2005-10-12 2012-04-17 Synthes Usa, Llc Apparatus and methods for vertebral augmentation
US8357181B2 (en) 2005-10-27 2013-01-22 Warsaw Orthopedic, Inc. Intervertebral prosthetic device for spinal stabilization and method of implanting same
EP1968505A4 (en) * 2005-11-23 2011-12-28 Crosstrees Medical Inc Devices and methods for the treatment of bone fracture
US20070162132A1 (en) 2005-12-23 2007-07-12 Dominique Messerli Flexible elongated chain implant and method of supporting body tissue with same
US8506633B2 (en) * 2005-12-27 2013-08-13 Warsaw Orthopedic, Inc. Rehydration and restoration of intervertebral discs with polyelectrolytes
US8801790B2 (en) * 2005-12-27 2014-08-12 Warsaw Orthopedic, Inc. Intervertebral disc augmentation and rehydration with superabsorbent polymers
US20070168039A1 (en) * 2006-01-13 2007-07-19 Sdgi Holdings, Inc. Materials, devices and methods for treating multiple spinal regions including vertebral body and endplate regions
US20070173820A1 (en) * 2006-01-13 2007-07-26 Sdgi Holdings, Inc. Materials, devices, and methods for treating multiple spinal regions including the anterior region
US20070173821A1 (en) * 2006-01-13 2007-07-26 Sdgi Holdings, Inc. Materials, devices, and methods for treating multiple spinal regions including the posterior and spinous process regions
US20070173823A1 (en) 2006-01-18 2007-07-26 Sdgi Holdings, Inc. Intervertebral prosthetic device for spinal stabilization and method of implanting same
US8083795B2 (en) 2006-01-18 2011-12-27 Warsaw Orthopedic, Inc. Intervertebral prosthetic device for spinal stabilization and method of manufacturing same
US7691130B2 (en) 2006-01-27 2010-04-06 Warsaw Orthopedic, Inc. Spinal implants including a sensor and methods of use
US7682376B2 (en) 2006-01-27 2010-03-23 Warsaw Orthopedic, Inc. Interspinous devices and methods of use
US20070213717A1 (en) * 2006-02-14 2007-09-13 Sdgi Holdings, Inc. Biological fusion in the vertebral column
US20070213822A1 (en) * 2006-02-14 2007-09-13 Sdgi Holdings, Inc. Treatment of the vertebral column
US20070213718A1 (en) * 2006-02-14 2007-09-13 Sdgi Holdings, Inc. Treatment of the vertebral column
US20070227547A1 (en) * 2006-02-14 2007-10-04 Sdgi Holdings, Inc. Treatment of the vertebral column
US7918889B2 (en) * 2006-02-27 2011-04-05 Warsaw Orthopedic, Inc. Expandable spinal prosthetic devices and associated methods
US8262698B2 (en) 2006-03-16 2012-09-11 Warsaw Orthopedic, Inc. Expandable device for insertion between anatomical structures and a procedure utilizing same
US7993404B2 (en) * 2006-03-29 2011-08-09 Warsaw Orthopedic, Inc. Transformable spinal implants and methods of use
US20070233245A1 (en) * 2006-03-31 2007-10-04 Sdgi Holdings, Inc. Methods and instruments for delivering intervertebral devices
US8147500B2 (en) * 2006-04-20 2012-04-03 Depuy Spine, Inc. Instrumentation kit for delivering viscous bone filler material
US8118844B2 (en) 2006-04-24 2012-02-21 Warsaw Orthopedic, Inc. Expandable device for insertion between anatomical structures and a procedure utilizing same
US20070255286A1 (en) * 2006-04-27 2007-11-01 Sdgi Holdings, Inc. Devices, apparatus, and methods for improved disc augmentation
US8133279B2 (en) 2006-04-27 2012-03-13 Warsaw Orthopedic, Inc. Methods for treating an annulus defect of an intervertebral disc
US20070255406A1 (en) * 2006-04-27 2007-11-01 Sdgi Holdings, Inc. Devices, apparatus, and methods for bilateral approach to disc augmentation
US8048118B2 (en) 2006-04-28 2011-11-01 Warsaw Orthopedic, Inc. Adjustable interspinous process brace
US8062337B2 (en) 2006-05-04 2011-11-22 Warsaw Orthopedic, Inc. Expandable device for insertion between anatomical structures and a procedure utilizing same
US8147517B2 (en) 2006-05-23 2012-04-03 Warsaw Orthopedic, Inc. Systems and methods for adjusting properties of a spinal implant
US20070276496A1 (en) 2006-05-23 2007-11-29 Sdgi Holdings, Inc. Surgical spacer with shape control
US20080009876A1 (en) * 2006-07-07 2008-01-10 Meera Sankaran Medical device with expansion mechanism
US8048119B2 (en) 2006-07-20 2011-11-01 Warsaw Orthopedic, Inc. Apparatus for insertion between anatomical structures and a procedure utilizing same
US20080058931A1 (en) * 2006-07-21 2008-03-06 John White Expandable vertebral implant and methods of use
US20080058954A1 (en) * 2006-08-22 2008-03-06 Hai Trieu Methods of treating spinal injuries using injectable flowable compositions comprising organic materials
US20080086115A1 (en) 2006-09-07 2008-04-10 Warsaw Orthopedic, Inc. Intercostal spacer device and method for use in correcting a spinal deformity
US9017388B2 (en) * 2006-09-14 2015-04-28 Warsaw Orthopedic, Inc. Methods for correcting spinal deformities
US8097019B2 (en) 2006-10-24 2012-01-17 Kyphon Sarl Systems and methods for in situ assembly of an interspinous process distraction implant
FR2908035B1 (en) 2006-11-08 2009-05-01 Jean Taylor interspinous implant
US20080114402A1 (en) * 2006-11-10 2008-05-15 Warsaw Orthopedic, Inc. Devices and Methods for Correcting a Spinal Deformity
US7879104B2 (en) 2006-11-15 2011-02-01 Warsaw Orthopedic, Inc. Spinal implant system
US20080114364A1 (en) * 2006-11-15 2008-05-15 Aoi Medical, Inc. Tissue cavitation device and method
US7955392B2 (en) 2006-12-14 2011-06-07 Warsaw Orthopedic, Inc. Interspinous process devices and methods
US9480485B2 (en) 2006-12-15 2016-11-01 Globus Medical, Inc. Devices and methods for vertebrostenting
US7909873B2 (en) 2006-12-15 2011-03-22 Soteira, Inc. Delivery apparatus and methods for vertebrostenting
US7972382B2 (en) 2006-12-26 2011-07-05 Warsaw Orthopedic, Inc. Minimally invasive spinal distraction devices and methods
US8377098B2 (en) 2007-01-19 2013-02-19 Flexuspine, Inc. Artificial functional spinal unit system and method for use
EP2124778A4 (en) 2007-02-21 2013-03-20 Benvenue Medical Inc Devices for treating the spine
EP2124777A4 (en) 2007-02-21 2013-06-05 Benvenue Medical Inc Devices for treating the spine
US20080255569A1 (en) * 2007-03-02 2008-10-16 Andrew Kohm Bone support device, system, and method
GB0707394D0 (en) * 2007-04-17 2007-05-23 Smith & Nephew Shape memory spine jack
EP2164405A2 (en) 2007-05-21 2010-03-24 AOI Medical Inc. Articulating cavitation device
WO2009036466A1 (en) * 2007-09-14 2009-03-19 Crosstrees Medical, Inc. Material control device for inserting material into a targeted anatomical region
US20090088789A1 (en) * 2007-09-28 2009-04-02 O'neil Michael J Balloon With Shape Control For Spinal Procedures
US8162994B2 (en) 2007-10-22 2012-04-24 Flexuspine, Inc. Posterior stabilization system with isolated, dual dampener systems
US8182514B2 (en) * 2007-10-22 2012-05-22 Flexuspine, Inc. Dampener system for a posterior stabilization system with a fixed length elongated member
US8523912B2 (en) 2007-10-22 2013-09-03 Flexuspine, Inc. Posterior stabilization systems with shared, dual dampener systems
US8267965B2 (en) 2007-10-22 2012-09-18 Flexuspine, Inc. Spinal stabilization systems with dynamic interbody devices
US8187330B2 (en) 2007-10-22 2012-05-29 Flexuspine, Inc. Dampener system for a posterior stabilization system with a variable length elongated member
US8157844B2 (en) * 2007-10-22 2012-04-17 Flexuspine, Inc. Dampener system for a posterior stabilization system with a variable length elongated member
CA2705709C (en) * 2007-11-16 2016-03-15 Synthes Usa, Llc Porous containment device and associated method for stabilization of vertebral compression fractures
US20090198245A1 (en) * 2008-02-04 2009-08-06 Phan Christopher U Tools and methods for insertion and removal of medical implants
US20090198338A1 (en) 2008-02-04 2009-08-06 Phan Christopher U Medical implants and methods
US9247943B1 (en) 2009-02-06 2016-02-02 Kleiner Intellectual Property, Llc Devices and methods for preparing an intervertebral workspace
US8088163B1 (en) 2008-02-06 2012-01-03 Kleiner Jeffrey B Tools and methods for spinal fusion
USD656610S1 (en) 2009-02-06 2012-03-27 Kleiner Jeffrey B Spinal distraction instrument
US8267939B2 (en) 2008-02-28 2012-09-18 Stryker Spine Tool for implanting expandable intervertebral implant
US20090222096A1 (en) * 2008-02-28 2009-09-03 Warsaw Orthopedic, Inc. Multi-compartment expandable devices and methods for intervertebral disc expansion and augmentation
US8114136B2 (en) 2008-03-18 2012-02-14 Warsaw Orthopedic, Inc. Implants and methods for inter-spinous process dynamic stabilization of a spinal motion segment
US7909857B2 (en) * 2008-03-26 2011-03-22 Warsaw Orthopedic, Inc. Devices and methods for correcting spinal deformities
WO2009125242A1 (en) 2008-04-08 2009-10-15 Vexim Apparatus for restoration of the spine and methods of use thereof
US20090281549A1 (en) * 2008-05-12 2009-11-12 Cook Incorporated Bone cement mixing and delivery device and method of use
WO2009155319A1 (en) 2008-06-17 2009-12-23 Soteira, Inc. Devices and methods for fracture reduction
US8114131B2 (en) 2008-11-05 2012-02-14 Kyphon Sarl Extension limiting devices and methods of use for the spine
US9717403B2 (en) 2008-12-05 2017-08-01 Jeffrey B. Kleiner Method and apparatus for performing retro peritoneal dissection
US8366748B2 (en) 2008-12-05 2013-02-05 Kleiner Jeffrey Apparatus and method of spinal implant and fusion
US9011539B2 (en) * 2009-01-21 2015-04-21 Warsaw Orthopedic, Inc. Spinal nucleus replacement implant
WO2010094032A3 (en) 2009-02-16 2010-11-11 Aoi Medical Inc. Trauma nail accumulator
WO2010103344A1 (en) 2009-03-12 2010-09-16 Vexim Apparatus for bone restoration of the spine and methods of use
US8535327B2 (en) 2009-03-17 2013-09-17 Benvenue Medical, Inc. Delivery apparatus for use with implantable medical devices
US8911497B2 (en) * 2009-04-09 2014-12-16 DePuy Synthes Products, LLC Minimally invasive spine augmentation and stabilization system and method
US8372117B2 (en) 2009-06-05 2013-02-12 Kyphon Sarl Multi-level interspinous implants and methods of use
US8157842B2 (en) 2009-06-12 2012-04-17 Kyphon Sarl Interspinous implant and methods of use
US9173694B2 (en) 2009-09-18 2015-11-03 Spinal Surgical Strategies, Llc Fusion cage with combined biological delivery system
US8906028B2 (en) 2009-09-18 2014-12-09 Spinal Surgical Strategies, Llc Bone graft delivery device and method of using the same
US8685031B2 (en) 2009-09-18 2014-04-01 Spinal Surgical Strategies, Llc Bone graft delivery system
US9629729B2 (en) 2009-09-18 2017-04-25 Spinal Surgical Strategies, Llc Biological delivery system with adaptable fusion cage interface
US9186193B2 (en) 2009-09-18 2015-11-17 Spinal Surgical Strategies, Llc Fusion cage with combined biological delivery system
US9060877B2 (en) 2009-09-18 2015-06-23 Spinal Surgical Strategies, Llc Fusion cage with combined biological delivery system
US8211126B2 (en) * 2009-09-22 2012-07-03 Jmea Corporation Tissue repair system
US8771317B2 (en) 2009-10-28 2014-07-08 Warsaw Orthopedic, Inc. Interspinous process implant and method of implantation
US20120016371A1 (en) * 2009-12-07 2012-01-19 O'halloran Damien Methods and Apparatus For Treating Vertebral Fractures
US9526538B2 (en) * 2009-12-07 2016-12-27 Globus Medical, Inc. Methods and apparatus for treating vertebral fractures
US8317831B2 (en) 2010-01-13 2012-11-27 Kyphon Sarl Interspinous process spacer diagnostic balloon catheter and methods of use
US8114132B2 (en) 2010-01-13 2012-02-14 Kyphon Sarl Dynamic interspinous process device
US8147526B2 (en) 2010-02-26 2012-04-03 Kyphon Sarl Interspinous process spacer diagnostic parallel balloon catheter and methods of use
US9168063B2 (en) * 2010-03-07 2015-10-27 Faisal Mirza Void containment apparatus and method of use for creating a sealed environment for product delivery
EP2547292A4 (en) * 2010-03-16 2013-09-18 Pinnacle Spine Group Llc Intervertebral implants and graft delivery systems and methods
US8864654B2 (en) 2010-04-20 2014-10-21 Jeffrey B. Kleiner Method and apparatus for performing retro peritoneal dissection
EP2575652A4 (en) * 2010-05-28 2013-11-13 Benvenue Medical Inc Disc space sizing devices and methods of using the same
US20120150299A1 (en) * 2010-06-10 2012-06-14 Ergun Asli Integrated multi-zonal cage/core implants as bone graft substitutes and apparatus and method for their fabrication
US9144501B1 (en) 2010-07-16 2015-09-29 Nuvasive, Inc. Fracture reduction device and methods
US8814908B2 (en) 2010-07-26 2014-08-26 Warsaw Orthopedic, Inc. Injectable flexible interspinous process device system
WO2012047859A3 (en) 2010-10-05 2013-10-17 Lorio Morgan P Intervertebral device and methods of use
EP2624773A4 (en) 2010-10-05 2014-09-17 Lorio Morgan Minimally invasive intervertebral systems and methods
EP2627288A1 (en) * 2010-10-14 2013-08-21 Synthes GmbH Double threaded guidance or stiffening wire for multiple use vertebral augmentation (va) balloon
US9101430B2 (en) 2010-10-14 2015-08-11 DePuy Synthes Products, Inc. Double threaded guidance or stiffening wire for multiple use vertebral augmentation (VA) balloon
US8617240B2 (en) * 2010-11-17 2013-12-31 Charles D. Hightower Moldable cushion for implants
US8388687B2 (en) 2011-03-25 2013-03-05 Flexuspine, Inc. Interbody device insertion systems and methods
US8591548B2 (en) 2011-03-31 2013-11-26 Warsaw Orthopedic, Inc. Spinous process fusion plate assembly
JP5847289B2 (en) 2011-04-07 2016-01-20 ヴェクシム ソシエテアノニム Expandable orthopedic equipment
US8591549B2 (en) 2011-04-08 2013-11-26 Warsaw Orthopedic, Inc. Variable durometer lumbar-sacral implant
JP6158173B2 (en) * 2011-05-10 2017-07-05 シンセス・ゲーエムベーハーSynthes GmbH Interference cage of the facet joint
US8814873B2 (en) 2011-06-24 2014-08-26 Benvenue Medical, Inc. Devices and methods for treating bone tissue
JP6047571B2 (en) 2011-08-16 2016-12-21 ストライカー・スピン Expandable graft
US9445848B2 (en) 2011-10-21 2016-09-20 Innovative Surgical Designs, Inc. Surgical implants for percutaneous lengthening of spinal pedicles to correct spinal stenosis
US9198765B1 (en) 2011-10-31 2015-12-01 Nuvasive, Inc. Expandable spinal fusion implants and related methods
US9380932B1 (en) 2011-11-02 2016-07-05 Pinnacle Spine Group, Llc Retractor devices for minimally invasive access to the spine
US9526627B2 (en) 2011-11-17 2016-12-27 Exactech, Inc. Expandable interbody device system and method
DE102012003247A1 (en) * 2012-02-20 2013-08-22 Bentley Surgical Gmbh Vertebral stent for implantation into vertebral body, is transported in elongated mold in application pipe and fulfills supporting function in vertebral body in elongated mold, where vertebral stent is made of mold memory alloy
US20150157378A1 (en) * 2012-04-05 2015-06-11 Nlt Spine Ltd. Material delivery device
US9393126B2 (en) * 2012-04-20 2016-07-19 Peter L. Mayer Bilaterally placed disc prosthesis for spinal implant and method of bilateral placement
US9364339B2 (en) * 2012-04-30 2016-06-14 Peter L. Mayer Unilaterally placed expansile spinal prosthesis
CN104582639A (en) * 2012-05-29 2015-04-29 Nlt-脊椎有限公司 Laterally deflectable implant
US9278008B2 (en) 2012-05-30 2016-03-08 Globus Medical, Inc. Expandable interbody spacer
US9044342B2 (en) 2012-05-30 2015-06-02 Globus Medical, Inc. Expandable interbody spacer
EP2742914A1 (en) * 2012-12-14 2014-06-18 FACET-LINK Inc. Infinitely height-adjustable vertebral fusion implant
US9492288B2 (en) 2013-02-20 2016-11-15 Flexuspine, Inc. Expandable fusion device for positioning between adjacent vertebral bodies
WO2014134614A9 (en) 2013-03-01 2014-12-04 Bones And Spine Surgery Inc. Minimally invasive method and surgical tools for trans-psoas approach
US9795493B1 (en) 2013-03-15 2017-10-24 Nuvasive, Inc. Expandable intervertebral implant and methods of use thereof
USD723682S1 (en) 2013-05-03 2015-03-03 Spinal Surgical Strategies, Llc Bone graft delivery tool
US9539041B2 (en) 2013-09-12 2017-01-10 DePuy Synthes Products, Inc. Minimally invasive biomaterial injection system
US9456856B2 (en) * 2013-09-26 2016-10-04 Warsaw Orthopedic, Inc. Intrabody osteotomy implant and methods of use
US9364344B2 (en) 2013-10-03 2016-06-14 Amendia, Inc. Expandable spinal implant
US20170095342A9 (en) * 2013-10-07 2017-04-06 Warsaw Orthopedic, Inc. Spinal implant system and method
US9545283B2 (en) * 2013-12-23 2017-01-17 Jmea Corporation Devices and methods for preparation of vertebral members
US9498266B2 (en) * 2014-02-12 2016-11-22 Wright Medical Technology, Inc. Intramedullary implant, system, and method for inserting an implant into a bone
US9517144B2 (en) 2014-04-24 2016-12-13 Exactech, Inc. Limited profile intervertebral implant with incorporated fastening mechanism
CN104306054B (en) * 2014-09-30 2016-09-14 上海君联医疗设备有限公司 An expandable stent vertebroplasty
USD750249S1 (en) 2014-10-20 2016-02-23 Spinal Surgical Strategies, Llc Expandable fusion cage
USD797290S1 (en) 2015-10-19 2017-09-12 Spinal Surgical Strategies, Llc Bone graft delivery tool
WO2017074277A1 (en) * 2015-10-26 2017-05-04 Tobb Ekonomi Ve Teknoloji Universitesi An expandable cage
US20170360570A1 (en) * 2016-02-22 2017-12-21 Conventus Orthopaedics, Inc. Apparatus and methods for spine and sacroiliac joint repair
CN106725813A (en) * 2016-12-06 2017-05-31 苏州爱得科技发展股份有限公司 Spine transplanting strutting implement

Citations (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6183517B2 (en) *
US1947649A (en) * 1931-12-05 1934-02-20 Godfrey J Kadavy Surgical instrument
US1965653A (en) * 1932-11-01 1934-07-10 James W Kennedy Dilator
US3049125A (en) * 1960-03-28 1962-08-14 Kriwkowitsch George Nose packing device
US3091237A (en) * 1960-05-16 1963-05-28 Clawson N Skinner Facial muscle and tissue conditioning device
US3648294A (en) * 1969-02-08 1972-03-14 Esfandiar Shahrestani Endoprostheses, especially for hip joints
US3800788A (en) * 1972-07-12 1974-04-02 N White Antral catheter for reduction of fractures
US3875595A (en) * 1974-04-15 1975-04-08 Edward C Froning Intervertebral disc prosthesis and instruments for locating same
US3889665A (en) * 1972-03-08 1975-06-17 Nat Res Dev Apparatus and method for pressurizing gap-filling cement to a concavely relieved site in a bone
US4018230A (en) * 1974-04-04 1977-04-19 Kazuo Ochiai Cervical dilator
US4083369A (en) * 1976-07-02 1978-04-11 Manfred Sinnreich Surgical instruments
US4274163A (en) * 1979-07-16 1981-06-23 The Regents Of The University Of California Prosthetic fixation technique
US4313434A (en) * 1980-10-17 1982-02-02 David Segal Fracture fixation
US4327736A (en) * 1979-11-20 1982-05-04 Kanji Inoue Balloon catheter
US4367816A (en) * 1981-06-10 1983-01-11 Wilkes Kenneth R Tear strip for gas sterilizable package and package
US4369772A (en) * 1980-04-28 1983-01-25 University Of Florida Method for strengthening a fractured bone
US4399814A (en) * 1981-04-27 1983-08-23 Massachusetts Institute Of Technology Method and apparatus for pressure-coated bones
US4432358A (en) * 1982-01-22 1984-02-21 Fixel Irving E Compression hip screw apparatus
US4462394A (en) * 1982-05-03 1984-07-31 Howmedica, Inc. Intramedullary canal seal for cement pressurization
US4466435A (en) * 1981-09-04 1984-08-21 Murray William M Bone cement nozzle and method
US4467479A (en) * 1982-02-05 1984-08-28 Brody Garry S Method of surgically repairing an injured human joint and a prosthetic device therefor
US4562598A (en) * 1981-04-01 1986-01-07 Mecron Medizinische Produkte Gmbh Joint prosthesis
US4595006A (en) * 1982-08-16 1986-06-17 Burke Dennis W Apparatus for cemented implantation of prostheses
US4637396A (en) * 1984-10-26 1987-01-20 Cook, Incorporated Balloon catheter
US4653489A (en) * 1984-04-02 1987-03-31 Tronzo Raymond G Fenestrated hip screw and method of augmented fixation
US4685447A (en) * 1985-03-25 1987-08-11 Pmt Corporation Tissue expander system
US4686973A (en) * 1984-10-12 1987-08-18 Dow Corning Corporation Method of making an intramedullary bone plug and bone plug made thereby
US4772287A (en) * 1987-08-20 1988-09-20 Cedar Surgical, Inc. Prosthetic disc and method of implanting
US4863477A (en) * 1987-05-12 1989-09-05 Monson Gary L Synthetic intervertebral disc prosthesis
US4892550A (en) * 1985-12-30 1990-01-09 Huebsch Donald L Endoprosthesis device and method
US4896662A (en) * 1987-11-30 1990-01-30 Pfizer Hospital Products Group, Inc. Sealing device for introducing cement into a bone canal
US4932975A (en) * 1989-10-16 1990-06-12 Vanderbilt University Vertebral prosthesis
US4932969A (en) * 1987-01-08 1990-06-12 Sulzer Brothers Limited Joint endoprosthesis
US4987892A (en) * 1989-04-04 1991-01-29 Krag Martin H Spinal fixation device
US5002576A (en) * 1988-06-06 1991-03-26 Mecron Medizinische Produkte Gmbh Intervertebral disk endoprosthesis
US5015255A (en) * 1989-05-10 1991-05-14 Spine-Tech, Inc. Spinal stabilization method
US5102413A (en) * 1990-11-14 1992-04-07 Poddar Satish B Inflatable bone fixation device
US5108404A (en) * 1989-02-09 1992-04-28 Arie Scholten Surgical protocol for fixation of bone using inflatable device
US5127912A (en) * 1990-10-05 1992-07-07 R. Charles Ray Sacral implant system
US5137512A (en) * 1989-03-17 1992-08-11 Scimed Life Systems, Inc. Multisegment balloon protector for dilatation catheter
US5176683A (en) * 1991-04-22 1993-01-05 Kimsey Timothy P Prosthesis press and method of using the same
US5176692A (en) * 1991-12-09 1993-01-05 Wilk Peter J Method and surgical instrument for repairing hernia
US5232446A (en) * 1991-10-30 1993-08-03 Scimed Life Systems, Inc. Multi-sinus perfusion balloon dilatation catheter
US5236460A (en) * 1990-02-12 1993-08-17 Midas Rex Pneumatic Tools, Inc. Vertebral body prosthesis
US5290306A (en) * 1989-11-29 1994-03-01 Cordis Corporation Puncture resistant balloon catheter
US5295994A (en) * 1991-11-15 1994-03-22 Bonutti Peter M Active cannulas
US5303718A (en) * 1990-12-29 1994-04-19 Milan Krajicek Method and device for the osteosynthesis of bones
US5330429A (en) * 1989-05-09 1994-07-19 Toray Industries, Inc. Catheter with a balloon reinforced with composite yarn
US5331975A (en) * 1990-03-02 1994-07-26 Bonutti Peter M Fluid operated retractors
US5383932A (en) * 1993-04-27 1995-01-24 Johnson & Johnson Professional, Inc. Absorbable medullary plug
US5390683A (en) * 1991-02-22 1995-02-21 Pisharodi; Madhavan Spinal implantation methods utilizing a middle expandable implant
US5423850A (en) * 1993-10-01 1995-06-13 Berger; J. Lee Balloon compressor for internal fixation of bone fractures
US5425710A (en) * 1993-10-26 1995-06-20 Medtronic, Inc. Coated sleeve for wrapping dilatation catheter balloons
US5439447A (en) * 1994-02-09 1995-08-08 Baxter International Inc. Balloon dilation catheter with hypotube
US5441538A (en) * 1993-04-12 1995-08-15 Bonutti; Peter M. Bone implant and method of securing
US5445639A (en) * 1989-05-10 1995-08-29 Spine-Tech, Inc. Intervertebral reamer construction
US5480400A (en) * 1993-10-01 1996-01-02 Berger; J. Lee Method and device for internal fixation of bone fractures
US5514143A (en) * 1991-11-27 1996-05-07 Apogee Medical Products, Inc. Apparatus and method for use during surgery
US5522790A (en) * 1991-05-29 1996-06-04 Origin Medsystems, Inc. Retraction apparatus and methods for endoscopic surgery
US5522846A (en) * 1993-05-14 1996-06-04 Bonutti; Peter M. Suture anchor
US5527624A (en) * 1991-11-22 1996-06-18 The Lubrizol Corporation Process for preparing sintered shapes and compositions used therein
US5531856A (en) * 1991-05-29 1996-07-02 Origin Medsystems, Inc. Endoscopic inflatable retraction devices
US5540711A (en) * 1992-06-02 1996-07-30 General Surgical Innovations, Inc. Apparatus and method for developing an anatomic space for laparoscopic procedures with laparoscopic visualization
US5545222A (en) * 1991-08-12 1996-08-13 Bonutti; Peter M. Method using human tissue
US5549388A (en) * 1995-05-22 1996-08-27 Wilkes; Kenneth R. Pleated sterilization pouch
US5549679A (en) * 1994-05-20 1996-08-27 Kuslich; Stephen D. Expandable fabric implant for stabilizing the spinal motion segment
US5645597A (en) * 1995-12-29 1997-07-08 Krapiva; Pavel I. Disc replacement method and apparatus
US5755690A (en) * 1987-01-09 1998-05-26 C. R. Bard Multiple layer high strength balloon for dilatation catheter
US5785647A (en) * 1996-07-31 1998-07-28 United States Surgical Corporation Surgical instruments useful for spinal surgery
US5788703A (en) * 1995-02-17 1998-08-04 Allo Pro Ag Apparatus for the placement of a medullary space blocker
US5893840A (en) * 1991-01-04 1999-04-13 Medtronic, Inc. Releasable microcapsules on balloon catheters
US5928284A (en) * 1998-07-09 1999-07-27 Mehdizadeh; Hamid M. Disc replacement prosthesis
US6015436A (en) * 1996-06-07 2000-01-18 Heinrich Ulrich Implant for filling a space between vertebrae
US6039761A (en) * 1997-02-12 2000-03-21 Li Medical Technologies, Inc. Intervertebral spacer and tool and method for emplacement thereof
US6066154A (en) * 1994-01-26 2000-05-23 Kyphon Inc. Inflatable device for use in surgical protocol relating to fixation of bone
US6174334B1 (en) * 1998-12-16 2001-01-16 Loubert Suddaby Expandable intervertebral fusion implant and applicator
US6190414B1 (en) * 1996-10-31 2001-02-20 Surgical Dynamics Inc. Apparatus for fusion of adjacent bone structures
US6241734B1 (en) * 1998-08-14 2001-06-05 Kyphon, Inc. Systems and methods for placing materials into bone
US6248110B1 (en) * 1994-01-26 2001-06-19 Kyphon, Inc. Systems and methods for treating fractured or diseased bone using expandable bodies
US6280456B1 (en) * 1997-08-15 2001-08-28 Kyphon Inc Methods for treating bone
US20020058994A1 (en) * 2000-11-16 2002-05-16 Hill J Donald Automatic suture fixation apparatus and method for minimally invasive cardiac surgery
US6402785B1 (en) * 1999-06-04 2002-06-11 Sdgi Holdings, Inc. Artificial disc implant
US6409766B1 (en) * 1998-07-30 2002-06-25 Expanding Concepts, Llc Collapsible and expandable interbody fusion device
US6419704B1 (en) * 1999-10-08 2002-07-16 Bret Ferree Artificial intervertebral disc replacement methods and apparatus
US6419705B1 (en) * 1999-06-23 2002-07-16 Sulzer Spine-Tech Inc. Expandable fusion device and method
US6436140B1 (en) * 1998-08-28 2002-08-20 Sofamor S.N.C. Expandable interbody fusion cage and method for insertion
US6440138B1 (en) * 1998-04-06 2002-08-27 Kyphon Inc. Structures and methods for creating cavities in interior body regions
US6454806B1 (en) * 1999-07-26 2002-09-24 Advanced Prosthetic Technologies, Inc. Spinal surgical prosthesis
US6527799B2 (en) * 1998-10-29 2003-03-04 Conor Medsystems, Inc. Expandable medical device with ductile hinges
US6582467B1 (en) * 2000-10-31 2003-06-24 Vertelink Corporation Expandable fusion cage
US6676665B2 (en) * 2000-08-11 2004-01-13 Sdgi Holdings, Inc. Surgical instrumentation and method for treatment of the spine
US20040102774A1 (en) * 2002-11-21 2004-05-27 Trieu Hai H. Systems and techniques for intravertebral spinal stabilization with expandable devices
US20040133280A1 (en) * 2002-11-21 2004-07-08 Trieu Hai H. Systems and techniques for interbody spinal stabilization with expandable devices
US20050080425A1 (en) * 2002-03-18 2005-04-14 Mohit Bhatnagar Minimally invasive bone manipulation device and method of use
US7070598B2 (en) * 2002-06-25 2006-07-04 Sdgi Holdings, Inc. Minimally invasive expanding spacer and method
US7087055B2 (en) * 2002-06-25 2006-08-08 Sdgi Holdings, Inc. Minimally invasive expanding spacer and method

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8620937D0 (en) 1986-08-29 1986-10-08 Shepperd J A N Spinal implant
US5059193A (en) * 1989-11-20 1991-10-22 Spine-Tech, Inc. Expandable spinal implant and surgical method
US5123926A (en) * 1991-02-22 1992-06-23 Madhavan Pisharodi Artificial spinal prosthesis
US5171278A (en) * 1991-02-22 1992-12-15 Madhavan Pisharodi Middle expandable intervertebral disk implants
CA2180556C (en) * 1994-01-26 2007-08-07 Mark A. Reiley Improved inflatable device for use in surgical protocol relating to fixation of bone
US5800550A (en) * 1996-03-13 1998-09-01 Sertich; Mario M. Interbody fusion cage
WO1998020939A3 (en) * 1996-11-15 1998-09-03 Advanced Bio Surfaces Inc Biomaterial system for in situ tissue repair
JP2001527437A (en) * 1997-03-07 2001-12-25 グローバーマン、オレン System for percutaneous bone and spinal stabilization, fixation and repair
US6159215A (en) * 1997-12-19 2000-12-12 Depuy Acromed, Inc. Insertion instruments and method for delivering a vertebral body spacer
DE60028186T2 (en) * 1999-01-27 2007-03-29 Disc-O-Tech Medical Technologies, Ltd. Expandable implant and to attach system
US6491724B1 (en) * 1999-08-13 2002-12-10 Bret Ferree Spinal fusion cage with lordosis correction
EP1792586B1 (en) 1999-09-14 2012-12-26 Spine Solutions Inc. Insert instrument for an implant between vertebrae
US6332894B1 (en) * 2000-03-07 2001-12-25 Zimmer, Inc. Polymer filled spinal fusion cage
US6635078B1 (en) * 2000-09-22 2003-10-21 Scimed Life Systems, Inc. Coated stents with better gripping ability
US6454807B1 (en) * 2000-11-30 2002-09-24 Roger P. Jackson Articulated expandable spinal fusion cage system
US6443989B1 (en) * 2000-12-04 2002-09-03 Roger P. Jackson Posterior expandable fusion cage
US6595998B2 (en) * 2001-03-08 2003-07-22 Spinewave, Inc. Tissue distraction device
US6632235B2 (en) * 2001-04-19 2003-10-14 Synthes (U.S.A.) Inflatable device and method for reducing fractures in bone and in treating the spine
EP1536743A2 (en) * 2002-08-27 2005-06-08 SDGI Holdings, Inc. Systems and methods for intravertebral reduction

Patent Citations (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6183517B2 (en) *
US6423083B1 (en) *
US1947649A (en) * 1931-12-05 1934-02-20 Godfrey J Kadavy Surgical instrument
US1965653A (en) * 1932-11-01 1934-07-10 James W Kennedy Dilator
US3049125A (en) * 1960-03-28 1962-08-14 Kriwkowitsch George Nose packing device
US3091237A (en) * 1960-05-16 1963-05-28 Clawson N Skinner Facial muscle and tissue conditioning device
US3648294A (en) * 1969-02-08 1972-03-14 Esfandiar Shahrestani Endoprostheses, especially for hip joints
US3889665A (en) * 1972-03-08 1975-06-17 Nat Res Dev Apparatus and method for pressurizing gap-filling cement to a concavely relieved site in a bone
US3800788A (en) * 1972-07-12 1974-04-02 N White Antral catheter for reduction of fractures
US4018230A (en) * 1974-04-04 1977-04-19 Kazuo Ochiai Cervical dilator
US3875595A (en) * 1974-04-15 1975-04-08 Edward C Froning Intervertebral disc prosthesis and instruments for locating same
US4083369A (en) * 1976-07-02 1978-04-11 Manfred Sinnreich Surgical instruments
US4274163A (en) * 1979-07-16 1981-06-23 The Regents Of The University Of California Prosthetic fixation technique
US4327736A (en) * 1979-11-20 1982-05-04 Kanji Inoue Balloon catheter
US4369772A (en) * 1980-04-28 1983-01-25 University Of Florida Method for strengthening a fractured bone
US4313434A (en) * 1980-10-17 1982-02-02 David Segal Fracture fixation
US4562598A (en) * 1981-04-01 1986-01-07 Mecron Medizinische Produkte Gmbh Joint prosthesis
US4399814A (en) * 1981-04-27 1983-08-23 Massachusetts Institute Of Technology Method and apparatus for pressure-coated bones
US4367816A (en) * 1981-06-10 1983-01-11 Wilkes Kenneth R Tear strip for gas sterilizable package and package
US4466435A (en) * 1981-09-04 1984-08-21 Murray William M Bone cement nozzle and method
US4432358A (en) * 1982-01-22 1984-02-21 Fixel Irving E Compression hip screw apparatus
US4467479A (en) * 1982-02-05 1984-08-28 Brody Garry S Method of surgically repairing an injured human joint and a prosthetic device therefor
US4462394A (en) * 1982-05-03 1984-07-31 Howmedica, Inc. Intramedullary canal seal for cement pressurization
US4595006A (en) * 1982-08-16 1986-06-17 Burke Dennis W Apparatus for cemented implantation of prostheses
US4653489A (en) * 1984-04-02 1987-03-31 Tronzo Raymond G Fenestrated hip screw and method of augmented fixation
US4686973A (en) * 1984-10-12 1987-08-18 Dow Corning Corporation Method of making an intramedullary bone plug and bone plug made thereby
US4637396A (en) * 1984-10-26 1987-01-20 Cook, Incorporated Balloon catheter
US4685447A (en) * 1985-03-25 1987-08-11 Pmt Corporation Tissue expander system
US4892550A (en) * 1985-12-30 1990-01-09 Huebsch Donald L Endoprosthesis device and method
US4932969A (en) * 1987-01-08 1990-06-12 Sulzer Brothers Limited Joint endoprosthesis
US5755690A (en) * 1987-01-09 1998-05-26 C. R. Bard Multiple layer high strength balloon for dilatation catheter
US4863477A (en) * 1987-05-12 1989-09-05 Monson Gary L Synthetic intervertebral disc prosthesis
US4772287A (en) * 1987-08-20 1988-09-20 Cedar Surgical, Inc. Prosthetic disc and method of implanting
US4896662A (en) * 1987-11-30 1990-01-30 Pfizer Hospital Products Group, Inc. Sealing device for introducing cement into a bone canal
US5002576A (en) * 1988-06-06 1991-03-26 Mecron Medizinische Produkte Gmbh Intervertebral disk endoprosthesis
US5108404A (en) * 1989-02-09 1992-04-28 Arie Scholten Surgical protocol for fixation of bone using inflatable device
US5137512A (en) * 1989-03-17 1992-08-11 Scimed Life Systems, Inc. Multisegment balloon protector for dilatation catheter
US4987892A (en) * 1989-04-04 1991-01-29 Krag Martin H Spinal fixation device
US5330429A (en) * 1989-05-09 1994-07-19 Toray Industries, Inc. Catheter with a balloon reinforced with composite yarn
US5015255A (en) * 1989-05-10 1991-05-14 Spine-Tech, Inc. Spinal stabilization method
US5445639A (en) * 1989-05-10 1995-08-29 Spine-Tech, Inc. Intervertebral reamer construction
US4932975A (en) * 1989-10-16 1990-06-12 Vanderbilt University Vertebral prosthesis
US5290306A (en) * 1989-11-29 1994-03-01 Cordis Corporation Puncture resistant balloon catheter
US5236460A (en) * 1990-02-12 1993-08-17 Midas Rex Pneumatic Tools, Inc. Vertebral body prosthesis
US5331975A (en) * 1990-03-02 1994-07-26 Bonutti Peter M Fluid operated retractors
US6017305A (en) * 1990-03-02 2000-01-25 General Surgical Innovations, Inc. Method of retracting bones
US5127912A (en) * 1990-10-05 1992-07-07 R. Charles Ray Sacral implant system
US5102413A (en) * 1990-11-14 1992-04-07 Poddar Satish B Inflatable bone fixation device
US5303718A (en) * 1990-12-29 1994-04-19 Milan Krajicek Method and device for the osteosynthesis of bones
US5893840A (en) * 1991-01-04 1999-04-13 Medtronic, Inc. Releasable microcapsules on balloon catheters
US5390683A (en) * 1991-02-22 1995-02-21 Pisharodi; Madhavan Spinal implantation methods utilizing a middle expandable implant
US5176683A (en) * 1991-04-22 1993-01-05 Kimsey Timothy P Prosthesis press and method of using the same
US5531856A (en) * 1991-05-29 1996-07-02 Origin Medsystems, Inc. Endoscopic inflatable retraction devices
US5522790A (en) * 1991-05-29 1996-06-04 Origin Medsystems, Inc. Retraction apparatus and methods for endoscopic surgery
US5545222A (en) * 1991-08-12 1996-08-13 Bonutti; Peter M. Method using human tissue
US5232446A (en) * 1991-10-30 1993-08-03 Scimed Life Systems, Inc. Multi-sinus perfusion balloon dilatation catheter
US5295994A (en) * 1991-11-15 1994-03-22 Bonutti Peter M Active cannulas
US5527624A (en) * 1991-11-22 1996-06-18 The Lubrizol Corporation Process for preparing sintered shapes and compositions used therein
US5514143A (en) * 1991-11-27 1996-05-07 Apogee Medical Products, Inc. Apparatus and method for use during surgery
US5176692A (en) * 1991-12-09 1993-01-05 Wilk Peter J Method and surgical instrument for repairing hernia
US5540711A (en) * 1992-06-02 1996-07-30 General Surgical Innovations, Inc. Apparatus and method for developing an anatomic space for laparoscopic procedures with laparoscopic visualization
US5441538A (en) * 1993-04-12 1995-08-15 Bonutti; Peter M. Bone implant and method of securing
US5383932A (en) * 1993-04-27 1995-01-24 Johnson & Johnson Professional, Inc. Absorbable medullary plug
US5522846A (en) * 1993-05-14 1996-06-04 Bonutti; Peter M. Suture anchor
US5527343A (en) * 1993-05-14 1996-06-18 Bonutti; Peter M. Suture anchor
US5480400A (en) * 1993-10-01 1996-01-02 Berger; J. Lee Method and device for internal fixation of bone fractures
US5423850A (en) * 1993-10-01 1995-06-13 Berger; J. Lee Balloon compressor for internal fixation of bone fractures
US5425710A (en) * 1993-10-26 1995-06-20 Medtronic, Inc. Coated sleeve for wrapping dilatation catheter balloons
US6423083B2 (en) * 1994-01-26 2002-07-23 Kyphon Inc. Inflatable device for use in surgical protocol relating to fixation of bone
US6248110B1 (en) * 1994-01-26 2001-06-19 Kyphon, Inc. Systems and methods for treating fractured or diseased bone using expandable bodies
US6066154A (en) * 1994-01-26 2000-05-23 Kyphon Inc. Inflatable device for use in surgical protocol relating to fixation of bone
US6235043B1 (en) * 1994-01-26 2001-05-22 Kyphon, Inc. Inflatable device for use in surgical protocol relating to fixation of bone
US5439447A (en) * 1994-02-09 1995-08-08 Baxter International Inc. Balloon dilation catheter with hypotube
US5549679A (en) * 1994-05-20 1996-08-27 Kuslich; Stephen D. Expandable fabric implant for stabilizing the spinal motion segment
US5788703A (en) * 1995-02-17 1998-08-04 Allo Pro Ag Apparatus for the placement of a medullary space blocker
US5549388A (en) * 1995-05-22 1996-08-27 Wilkes; Kenneth R. Pleated sterilization pouch
US5645597A (en) * 1995-12-29 1997-07-08 Krapiva; Pavel I. Disc replacement method and apparatus
US6015436A (en) * 1996-06-07 2000-01-18 Heinrich Ulrich Implant for filling a space between vertebrae
US5785647A (en) * 1996-07-31 1998-07-28 United States Surgical Corporation Surgical instruments useful for spinal surgery
US6190414B1 (en) * 1996-10-31 2001-02-20 Surgical Dynamics Inc. Apparatus for fusion of adjacent bone structures
US6039761A (en) * 1997-02-12 2000-03-21 Li Medical Technologies, Inc. Intervertebral spacer and tool and method for emplacement thereof
US6280456B1 (en) * 1997-08-15 2001-08-28 Kyphon Inc Methods for treating bone
US6440138B1 (en) * 1998-04-06 2002-08-27 Kyphon Inc. Structures and methods for creating cavities in interior body regions
US5928284A (en) * 1998-07-09 1999-07-27 Mehdizadeh; Hamid M. Disc replacement prosthesis
US6409766B1 (en) * 1998-07-30 2002-06-25 Expanding Concepts, Llc Collapsible and expandable interbody fusion device
US6241734B1 (en) * 1998-08-14 2001-06-05 Kyphon, Inc. Systems and methods for placing materials into bone
US6436140B1 (en) * 1998-08-28 2002-08-20 Sofamor S.N.C. Expandable interbody fusion cage and method for insertion
US6527799B2 (en) * 1998-10-29 2003-03-04 Conor Medsystems, Inc. Expandable medical device with ductile hinges
US6174334B1 (en) * 1998-12-16 2001-01-16 Loubert Suddaby Expandable intervertebral fusion implant and applicator
US6183517B1 (en) * 1998-12-16 2001-02-06 Loubert Suddaby Expandable intervertebral fusion implant and applicator
US6402785B1 (en) * 1999-06-04 2002-06-11 Sdgi Holdings, Inc. Artificial disc implant
US6419705B1 (en) * 1999-06-23 2002-07-16 Sulzer Spine-Tech Inc. Expandable fusion device and method
US6454806B1 (en) * 1999-07-26 2002-09-24 Advanced Prosthetic Technologies, Inc. Spinal surgical prosthesis
US6419704B1 (en) * 1999-10-08 2002-07-16 Bret Ferree Artificial intervertebral disc replacement methods and apparatus
US6676665B2 (en) * 2000-08-11 2004-01-13 Sdgi Holdings, Inc. Surgical instrumentation and method for treatment of the spine
US6582467B1 (en) * 2000-10-31 2003-06-24 Vertelink Corporation Expandable fusion cage
US20020058994A1 (en) * 2000-11-16 2002-05-16 Hill J Donald Automatic suture fixation apparatus and method for minimally invasive cardiac surgery
US20050080425A1 (en) * 2002-03-18 2005-04-14 Mohit Bhatnagar Minimally invasive bone manipulation device and method of use
US7087055B2 (en) * 2002-06-25 2006-08-08 Sdgi Holdings, Inc. Minimally invasive expanding spacer and method
US7070598B2 (en) * 2002-06-25 2006-07-04 Sdgi Holdings, Inc. Minimally invasive expanding spacer and method
US20040102774A1 (en) * 2002-11-21 2004-05-27 Trieu Hai H. Systems and techniques for intravertebral spinal stabilization with expandable devices
US20040133280A1 (en) * 2002-11-21 2004-07-08 Trieu Hai H. Systems and techniques for interbody spinal stabilization with expandable devices

Cited By (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100063595A1 (en) * 2004-11-24 2010-03-11 Dietz Terry L Adjustable knee tibial trial insert
US9277965B2 (en) 2004-11-24 2016-03-08 DePuy Synthes Products, Inc. Adjustable knee tibial trial insert
US8435304B2 (en) * 2004-11-24 2013-05-07 DePuy Synthes Products, LLC Adjustable knee tibial trial insert
US20110213402A1 (en) * 2005-05-24 2011-09-01 Kyphon Sarl Low-compliance expandable medical device
US20100064045A1 (en) * 2007-05-10 2010-03-11 Teliasonera Ab Handing a request relating to a service
US9034040B2 (en) 2007-08-31 2015-05-19 Globus Medical Inc. Devices and methods for treating bone
US9445856B2 (en) 2008-08-29 2016-09-20 Globus Medical, Inc. Devices and methods for treating bone
US8998992B2 (en) 2008-08-29 2015-04-07 Globus Medical, Inc. Devices and methods for treating bone
US8556979B2 (en) 2009-10-15 2013-10-15 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US9492287B2 (en) 2009-10-15 2016-11-15 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US9358128B2 (en) 2009-10-15 2016-06-07 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US9358126B2 (en) 2009-10-15 2016-06-07 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US8709086B2 (en) 2009-10-15 2014-04-29 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US9119730B2 (en) 2009-10-15 2015-09-01 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US9039771B2 (en) 2009-10-15 2015-05-26 Globus Medical, Inc Expandable fusion device and method of installation thereof
US8518120B2 (en) 2009-10-15 2013-08-27 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US8062375B2 (en) 2009-10-15 2011-11-22 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US20110093074A1 (en) * 2009-10-15 2011-04-21 Chad Glerum Expandable Fusion Device and Method of Installation Thereof
US9452063B2 (en) 2009-10-15 2016-09-27 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US9211196B2 (en) 2009-10-15 2015-12-15 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US8685098B2 (en) 2010-06-25 2014-04-01 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US8679183B2 (en) 2010-06-25 2014-03-25 Globus Medical Expandable fusion device and method of installation thereof
US9597200B2 (en) 2010-06-25 2017-03-21 Globus Medical, Inc Expandable fusion device and method of installation thereof
US9474625B2 (en) 2010-09-03 2016-10-25 Globus Medical, Inc Expandable fusion device and method of installation thereof
US8845734B2 (en) 2010-09-03 2014-09-30 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US9566168B2 (en) 2010-09-03 2017-02-14 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US9125757B2 (en) 2010-09-03 2015-09-08 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US9561116B2 (en) 2010-09-03 2017-02-07 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US8852279B2 (en) 2010-09-03 2014-10-07 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US9351848B2 (en) 2010-09-03 2016-05-31 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US9855151B2 (en) 2010-09-03 2018-01-02 Globus Medical, Inc Expandable fusion device and method of installation thereof
US8845731B2 (en) 2010-09-03 2014-09-30 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US9370434B2 (en) 2010-09-03 2016-06-21 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US8876866B2 (en) 2010-12-13 2014-11-04 Globus Medical, Inc. Spinous process fusion devices and methods thereof
US8518114B2 (en) 2011-04-21 2013-08-27 Warsaw Orthopedic, Inc. Expandable implant system and methods of use
US9901458B1 (en) 2011-09-23 2018-02-27 Samy Abdou Spinal fixation devices and methods of use
US9867714B1 (en) 2011-09-23 2018-01-16 Samy Abdou Spinal fixation devices and methods of use
US9610176B1 (en) 2011-09-23 2017-04-04 Samy Abdou Spinal fixation devices and methods of use
US8845728B1 (en) 2011-09-23 2014-09-30 Samy Abdou Spinal fixation devices and methods of use
US9314350B1 (en) 2011-09-23 2016-04-19 Samy Abdou Spinal fixation devices and methods of use
US8864833B2 (en) 2011-09-30 2014-10-21 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US9539108B2 (en) 2011-09-30 2017-01-10 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US20130116791A1 (en) * 2011-11-04 2013-05-09 Boo Holdings, Llc Expandable intervertebral spacer implant
US8771277B2 (en) 2012-05-08 2014-07-08 Globus Medical, Inc Device and a method for implanting a spinous process fixation device
US9486254B2 (en) 2012-05-08 2016-11-08 Globus Medical, Inc. Device and method for implanting a spinous process fixation device
US9980756B2 (en) 2012-05-08 2018-05-29 Globus Medical, Inc. Device and a method for implanting a spinous process fixation device
US9486251B2 (en) 2012-12-31 2016-11-08 Globus Medical, Inc. Spinous process fixation system and methods thereof
US9011493B2 (en) 2012-12-31 2015-04-21 Globus Medical, Inc. Spinous process fixation system and methods thereof
US9585765B2 (en) 2013-02-14 2017-03-07 Globus Medical, Inc Devices and methods for correcting vertebral misalignment
US9402738B2 (en) 2013-02-14 2016-08-02 Globus Medical, Inc. Devices and methods for correcting vertebral misalignment
US9782265B2 (en) 2013-02-15 2017-10-10 Globus Medical, Inc Articulating and expandable vertebral implant
US9204972B2 (en) 2013-03-01 2015-12-08 Globus Medical, Inc. Articulating expandable intervertebral implant
US9198697B2 (en) 2013-03-13 2015-12-01 Globus Medical, Inc. Spinous process fixation system and methods thereof
US9034045B2 (en) 2013-03-15 2015-05-19 Globus Medical, Inc Expandable intervertebral implant
US9186258B2 (en) 2013-03-15 2015-11-17 Globus Medical, Inc. Expandable intervertebral implant
US9149367B2 (en) 2013-03-15 2015-10-06 Globus Medical Inc Expandable intervertebral implant
US9788971B1 (en) 2013-05-22 2017-10-17 Nuvasive, Inc. Expandable fusion implant and related methods
US9801734B1 (en) 2013-08-09 2017-10-31 Nuvasive, Inc. Lordotic expandable interbody implant
US9402739B2 (en) 2014-02-07 2016-08-02 Globus Medical, Inc. Variable lordosis spacer and related methods of use
US9707100B2 (en) 2015-06-25 2017-07-18 Institute for Musculoskeletal Science and Education, Ltd. Interbody fusion device and system for implantation

Also Published As

Publication number Publication date Type
US20040102774A1 (en) 2004-05-27 application
US7758644B2 (en) 2010-07-20 grant
WO2004047689A1 (en) 2004-06-10 application

Similar Documents

Publication Publication Date Title
US8343193B2 (en) Method of supporting and distracting opposing vertebral bodies
US6500132B1 (en) Device and method for determining parameters of blind voids
US6764514B1 (en) Prosthetic apparatus and method
US20070213717A1 (en) Biological fusion in the vertebral column
US7799056B2 (en) Bone fusion device and methods
US6558386B1 (en) Axial spinal implant and method and apparatus for implanting an axial spinal implant within the vertebrae of the spine
US20110172716A1 (en) Expandable Spacer and Method For Use Thereof
US7465318B2 (en) Cement-directing orthopedic implants
US20070276491A1 (en) Mold assembly for intervertebral prosthesis
US20050055097A1 (en) Minimally invasive modular support implant device and method
US20070162132A1 (en) Flexible elongated chain implant and method of supporting body tissue with same
US20110144753A1 (en) Bellows-Like Expandable Interbody Fusion Cage
US20090234398A1 (en) Implantable devices and methods for treating micro-architecture deterioration of bone tissue
US6899719B2 (en) Systems and methods for treating fractured or diseased bone using expandable bodies
US20050154463A1 (en) Spinal nucleus replacement implants and methods
US7524333B2 (en) Method of anchoring an implant in an intervertebral disc
US20110054408A1 (en) Delivery systems, devices, tools, and methods of use
US20060085081A1 (en) Implants and methods for treating bone
US20080119853A1 (en) Methods and apparatus for minimally invasive modular interbody fusion devices
US7267687B2 (en) Spinal implant and method of use
US7204851B2 (en) Method and apparatus for delivering an intervertebral disc implant
US7094258B2 (en) Methods of reinforcing an annulus fibrosis
US6425919B1 (en) Devices and methods of vertebral disc augmentation
US20070118133A1 (en) Intervertebral disc anulus repair
US20060085009A1 (en) Implants and methods for treating bone

Legal Events

Date Code Title Description
AS Assignment

Owner name: ORTHOPHOENIX, LLC, TEXAS

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:WARSAW ORTHOPEDIC, INC.;REEL/FRAME:035267/0568

Effective date: 20130425