US20090030519A1 - Intervertebral cage designs - Google Patents

Intervertebral cage designs Download PDF

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Publication number
US20090030519A1
US20090030519A1 US11/764,997 US76499707A US2009030519A1 US 20090030519 A1 US20090030519 A1 US 20090030519A1 US 76499707 A US76499707 A US 76499707A US 2009030519 A1 US2009030519 A1 US 2009030519A1
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United States
Prior art keywords
implant
cage
shows
back wall
sidewalls
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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US11/764,997
Inventor
Mark H. Falahee
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U S Spine Inc
Original Assignee
Us Spinal Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US42061602P priority Critical
Priority to US10/691,854 priority patent/US7232463B2/en
Application filed by Us Spinal Technologies LLC filed Critical Us Spinal Technologies LLC
Priority to US11/764,997 priority patent/US20090030519A1/en
Publication of US20090030519A1 publication Critical patent/US20090030519A1/en
Assigned to U.S. SPINAL TECHNOLOGIES, LLC reassignment U.S. SPINAL TECHNOLOGIES, LLC ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: MEDICAL DESIGNS, LLC
Assigned to MEDICAL DESIGNS, LLC reassignment MEDICAL DESIGNS, LLC ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: FALAHEE, MARK H.
Assigned to US SPINE, INC. reassignment US SPINE, INC. CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: U.S. SPINAL TECHNOLOGIES, LLC
Assigned to ZIONS FIRST NATIONAL BANK reassignment ZIONS FIRST NATIONAL BANK SECURITY AGREEMENT Assignors: US SPINE, INC.
Assigned to KARL KIPKE, AS COLLATERAL AGENT reassignment KARL KIPKE, AS COLLATERAL AGENT SECURITY AGREEMENT Assignors: AMEDICA CORPORATION
Assigned to AMEDICA CORPORATION reassignment AMEDICA CORPORATION RELEASE BY SECURED PARTY (SEE DOCUMENT FOR DETAILS). Assignors: KARL KIPKE
Assigned to US SPINE, INC. reassignment US SPINE, INC. RELEASE BY SECURED PARTY (SEE DOCUMENT FOR DETAILS). Assignors: ZIONS FIRST NATIONAL BANK
Application status is Abandoned legal-status Critical

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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
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    • A61F2/46Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4601Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for introducing bone substitute, for implanting bone graft implants or for compacting them in the bone cavity
    • A61F2002/4602Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for introducing bone substitute, for implanting bone graft implants or for compacting them in the bone cavity for compacting
    • AHUMAN NECESSITIES
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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2/4603Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
    • A61F2002/4623Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof having a handle portion, e.g. integral with the implanting tool
    • A61F2002/4624Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof having a handle portion, e.g. integral with the implanting tool releasable from the implanting tool
    • AHUMAN NECESSITIES
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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
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    • A61F2/4603Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
    • A61F2002/4625Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use
    • A61F2002/4627Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use with linear motion along or rotating motion about the instrument axis or the implantation direction, e.g. telescopic, along a guiding rod, screwing inside the instrument
    • AHUMAN NECESSITIES
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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4603Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
    • A61F2002/4629Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof connected to the endoprosthesis or implant via a threaded connection
    • AHUMAN NECESSITIES
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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2/46Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2002/4635Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor using minimally invasive surgery
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    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
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    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0041Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements using additional screws, bolts, dowels or rivets, e.g. connecting screws
    • AHUMAN NECESSITIES
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    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0091Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements connected by a hinged linkage mechanism, e.g. of the single-bar or multi-bar linkage type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0004Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable
    • A61F2250/0009Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable for adjusting thickness
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0085Identification means; Administration of patients
    • A61F2250/0087Identification means; Administration of patients colour-coded
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0096Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
    • A61F2250/0098Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers

Abstract

Cage systems that improve upon the prior art in various ways. In the preferred embodiments, devices are radiolucent, with markers, thereby allowing visualization of placement without excessive obscuration. Devices according to the invention eliminate multiple steps, instruments and trays, while being capable of a custom fit. The devices according to the invention permit easier and greater access to end plate surface area, and can be used with autografts, allografts, and biologics.

Description

    REFERENCE TO RELATED APPLICATION
  • This application is a continuation of U.S. patent application Ser. No. 10/691,854, filed Oct. 23, 2003, which claims priority from U.S. Provisional Patent Application Ser. No. 60/420,616, filed Oct. 23, 2002, the entire content of both of which are incorporated herein by reference.
  • FIELD OF THE INVENTION
  • This invention relates generally to spinal implants and, in particular, to improved intervertebral cage designs.
  • BACKGROUND OF THE INVENTION
  • There are many intervertebral implants to assist with stabilization and fixation, including pre-assembled mesh rings of varying size; cylindrical threaded cages; carbon fiber boxes; and bone dowels, rings, and wedges. However, all existing devices have certain drawbacks, including the requirement of multiple steps and tools to prepare and mold the intervertebral plates for acceptance of the devices.
  • Existing implants also exhibit the need to remove/move a distraction device such as a spreader or plugs around a decorticate. Such plugs/distraction devices often get in the way of cage placement. Mesh cages in bone materials can deform or break with attempts to force them into the inner space. Typically, only a small surface of the end plate is exposed to bone graft, this being dictated by the size and position of the cage. Existing devices also require large trays with many instruments and many cages, and it is difficult to see the bone fused in mass inside metal cages, which are radiopaque.
  • SUMMARY OF THE INVENTION
  • This invention resides in cage systems that improve upon the prior art in various ways. In the preferred embodiments, devices are radiolucent, with markers, thereby allowing visualization of placement without excessive obscuration. Devices according to the invention eliminate multiple steps, instruments and trays, while being capable of a custom fit. The devices according to the invention permit easier and greater access to end plate surface area, and can be used with autografts, allografts, and biologics.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • FIG. 1 is a drawing that shows a preferred embodiment of the invention;
  • FIG. 2A is a drawing which shows a contoured, wedge-shaped retractor;
  • FIG. 2B shows a side view of a U-shaped introducer;
  • FIG. 2C shows a top view of the U-shaped introducer;
  • FIG. 2D shows the U-shaped introducer received within a cage;
  • FIG. 2E is a side view of a graft impactor;
  • FIG. 2F is a side view of the graft impactor but with an end view of the impactor tip;
  • FIG. 2G shows a gate holder with a screw mechanism used to capture and release a gate;
  • FIG. 2H is a drawing of a screwdriver;
  • FIG. 3A shows cage shapes for levels L2-L5;
  • FIG. 3B shows cage shapes for levels L5/S1;
  • FIG. 3C shows cage shapes for levels T/L2;
  • FIG. 4A shows how disc material is removed to determine the lateral extent of a disc space;
  • FIG. 4B is a drawing that shows a disc space being dilated to a desired height using distracters which are preferably color coded;
  • FIG. 4C shows a cage being inserted;
  • FIG. 4D illustrates how, with the implant released and the introducer tool removed, easy access is available to the end plates;
  • FIG. 4E shows how end plates are prepared, and grafting material, biologics, and so forth are packed in;
  • FIG. 5A is a first view of an implant according to the invention;
  • FIG. 5B is a second view of an implant according to the invention;
  • FIG. 6A is a drawing that shows how a proximal guide sleeve is attached onto one vertical side wall of the cage and drilled and tapped as necessary;
  • FIG. 6B shows a locking screw in position;
  • FIG. 6C shows how a universal screw driver/holder is used to place distal screws into the cage;
  • FIG. 6D depicts the lower aspect of a cage being locked into a distal vertebrae;
  • FIG. 6E is a lateral view of a cage in place;
  • FIG. 6F is an anterior-posterior (AP) view of a cage in place;
  • FIG. 7A begins a series of drawings that depict an alternative embodiment of the invention including a different form of anterior fixation;
  • FIG. 7B shows how a fixation jig is used to introduce a screw or similar device through the intervertebral body proximally into the superior cage walls
  • FIG. 7C shows how inferior fixation is accomplished with a ratchet screwdriver/holder to deliver a fastener through the inferior wall of the cage into the vertebral body
  • FIG. 7D is a drawing that shows how the screw preferably angles out laterally;
  • FIG. 7E depicts a fixed cage in place;
  • FIG. 8A shows the anchoring screw being pushed;
  • FIG. 8B shows the pins advanced;
  • FIG. 8C shows the device in-situ;
  • FIG. 9A shows the hinged contoured back wall with the inserter prior to use;
  • FIG. 9B shows the back wall being straightened and the side walls being spaced apart;
  • FIG. 10A illustrates a different embodiment involving a sliding lateral expandable cage with locking screws; and
  • FIG. 10B shows an expanded condition with the locking screws being used to stabilize the structure at a desired level of expansion.
  • DETAILED DESCRIPTION OF THE INVENTION
  • A first preferred embodiment of the invention is depicted in FIG. 1. This design includes an open-faced cage 102, which is constructed of carbon fiber or other radiolucent material but for small dot radiopaque markers (not shown). The device includes a contoured dome-shaped side walls 104, 104′ with a flat trapezoidal undersurface. Separate cages and tools may be used for the L5-S1 levels with more pronounced trapezoidal shapes. An indented back wall 110 is used to prevent neurocompression. The side walls preferably include a recessed face with nippled intents 112 and screw holes 114 to receive a locking screw 116. A closing face gate 120 is provided with non-slip nipples and locking screw holes as well.
  • In addition to the dome-shaped contours of the upper end plate, different shapes for the L5-S1 levels, and the indented back wall, the use of an open-face plate with gate and locking screw mechanism allows the device to be packed and closed in-situ, thereby effectively assembling the cage between the vertebrae. Note that although this design includes numerous features which are believed to be novel, they need not be used entirely in combination, but may be used separately or combined in subsets. The side view at the right in FIG. 1 illustrates the optional use of sawtooth features 125 on the upper surface 130, which is preferably dome-shaped, and the lower surface 140, which is preferably flat.
  • FIG. 2 is a series of drawings which shows the instruments used to implant devices according to the invention. Most or all are removably attached able to a ratchet handle 200. The set includes a screwdriver 202 (FIG. 2H); contoured, wedge-shaped retractors 206, preferably including a color-coded raised centering mark or ridge 207 (FIG. 2A); U-shaped introducers 208 (FIG. 2B), preferably including retractable wings 209 (FIG. 2C) to release a cage 210 (FIG. 2D) using control 211; graft impactors 220 (FIGS. 2E, 2F) and gate holder 230 including a screw mechanism 232 used to capture and release a gate 240 (FIG. 2G). The impactors 230 are generally 25 in length, and preferably come in different sizes, such as 0.8 cm at one end and 1-2 cm at the other, 0.5 cm at one end and 1 cm or less at the other, and so forth.
  • FIG. 3 shows how cage shapes would preferably be varied for different vertebral levels. FIG. 3A shows cage shapes for L2-L5; FIG. 3B shows cage shapes for L5/S1; and FIG. 3C shows cage shapes for T/L2. In each case, the implants would preferably utilize some or all of the other geometries described herein, including a general U-shaped construction, crescent-shaped side walls, domed tops, indented back wall, carbon fiber or other radiolucent construction with markers, serrated or tooth-edged, end-plate surfaces, and so forth. The devices would also preferably include correspondingly sized anterior gates, also utilizing carbon fiber or other radiolucent material, with non-slip nipples, locking screw holes and associated screws.
  • FIG. 4 is a series of drawings which show a method involving an anterior approach to the intervertebral space. In FIG. 4A, disc material is removed with tool 402 to determine the lateral extent of the space. In FIG. 4B, the disc space is dilated to a desired height using distracters 206 which are preferably color coded. The final distracter is removed and replaced with the same color-coded implant introducer instrument 208, with the cage being inserted as shown in FIG. 4C. The implant is released and the introducer tool removed, allowing easy access 410 to the end plates as shown in FIG. 4D.
  • In FIG. 4E, the end plates are prepared, and grafting material, biologics, and so forth are packed in. In FIG. 4F, a correspondingly sized anterior gate is locked into position using the gate holder and locking screws and screwdriver, and the wound is closed. FIG. 5 begins a series of drawings which shows an alternative embodiment of the invention which allows for an in-situ cage to act as a stand-alone radiolucent cage system. In addition to the instruments previously described, this embodiment utilizes proximal left/right guide sleeves, a drill and universal head screwdriver. In terms of the implant itself, proximal and distal screws are used in conjunction with an in-situ cage having a locking gate, in this case modified to accept proximal screws and guide inferior screws. Different views of the implant are shown in FIGS. 5A and 5B.
  • In terms of the operative procedure, the steps previously described involving cage insertion are followed. However, in this case, a proximal guide sleeve is attached onto one vertical side wall of the cage and drilled and tapped as necessary, as shown in FIG. 6A. The locking screw is shown in place in FIG. 6B. The universal screw driver/holder is used to place distal screws into the cage, as shown in FIG. 6C, allowing the lower aspect of the cage to be locked into the distal vertebrae as shown in FIG. 6D. FIG. 6E is a lateral view of the cage in place, and FIG. 6F is an A-P view.
  • Now turning to FIGS. 7 and higher, which depict yet a further alternative embodiment including a different form of anterior fixation. As shown in this case, a fixation jig 700 is used to introduce a screw or similar device through the intervertebral body proximally into the superior cage walls, as shown in FIG. 7B. Inferior fixation is accomplished with a ratchet screwdriver/holder 702 , which delivers the fastener through the inferior wall of the cage into the vertebral body as shown in FIG. 7C. The screw preferably angles out laterally, as shown in FIG. 7D, with the fixed cage in place in FIG. 7E. FIG. 8 is a series of drawings which shows internal fixation using an advancing screw to push a fixation pin into the cortical end plate. FIG. 8A shows the anchoring screw 802 being pushed, FIG. 8B shows the pins 804 advanced, and FIG. 8C shows the device in-situ.
  • FIG. 9 shows yet a different alternative embodiment of the invention in the form of a collapsing cage suitable for endoscopic placement. The cage is hinged enabling it to be laterally expandable with an expandable cage inserter. FIG. 9A shows the hinged contoured back wall 902 with the inserter prior to use, and FIG. 9B shows the back wall being straightened and the side walls being spaced apart. FIG. 10 shows a different embodiment involving a sliding lateral expandable cage 10 with locking screws 12. Again, an expandable cage inserter is used to move the side walls apart from the condition in FIG. 10A to the expanded condition in FIG. 10B with the locking screw being used to stabilize the structure at a desired level of expansion.

Claims (13)

1.-9. (canceled)
10. An implant for promoting intervertebral fusion, comprising:
a cage having two sidewalls, a posterior back wall, an open top, an open bottom, and an open front; and
wherein the back wall is expandable such that the sidewalls can be brought closer together for insertion and spread apart during implantation.
11. The implant of claim 10, wherein the side walls are substantially parallel during insertion and when spread apart.
12. The implant of claim 10, wherein:
the cage is comprised of two L-shaped pieces, each with a first section forming a respective one of the side walls and a second section forming a portion of the back wall; and
wherein the second sections of each L-shaped piece overlap in sliding engagement enabling the sidewalls to be brought closer together for insertion and spread apart during implantation.
13. The implant of claim 10, wherein:
the back wall is composed of two hinged sections hinged sections that collapse against the side walls for insertion and become substantially straightened out during implantation.
14. The implant of claim 10, wherein each sidewall has a convex upper edge and a substantially flat lower edge, such that when viewed from the side, the upper and lower edges conform to outwardly curved and flat planes, respectively.
15. The implant of claim 10, further including a physically separate, rigid gate element for closing the open front.
16. The implant of claim 15, wherein the cage and gate are constructed of a radiolucent material.
17. The implant of claim 15, wherein the cage and gate are constructed of carbon fiber.
18. The implant of claim 15, wherein:
the cage is constructed of a radiolucent material; and
further including one or more radiopaque markers on the cage.
19. The implant of claim 10, wherein the backwall is indented to minimize neurocompression.
20. The implant of claim 10, wherein:
the sidewalls have a posterior height and an anterior height; and
wherein the posterior height is less than the anterior height, thereby forming a trapezoid.
21. The implant of claim 10, wherein the anterior height, posterior height, or both, are sized to accommodate a particular vertebral level.
US11/764,997 2002-10-23 2007-06-19 Intervertebral cage designs Abandoned US20090030519A1 (en)

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US10/691,854 US7232463B2 (en) 2002-10-23 2003-10-23 Intervertebral cage designs
US11/764,997 US20090030519A1 (en) 2002-10-23 2007-06-19 Intervertebral cage designs

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US20050197706A1 (en) * 2004-02-04 2005-09-08 Ldr Medical, Inc. Intervertebral disc prosthesis
US20080200984A1 (en) * 2007-02-16 2008-08-21 Ldr Medical Intervertebral Disc Prosthesis Insertion Assemblies
US20090132054A1 (en) * 2004-12-22 2009-05-21 Ldr Medical Intervertebral Disc Prosthesis
US20100249935A1 (en) * 2009-03-30 2010-09-30 Slivka Michael A Zero Profile Spinal Fusion Cage
US20110077739A1 (en) * 2005-09-23 2011-03-31 Ldr Medical Intervertebral disc prosthesis
WO2012099864A1 (en) * 2011-01-18 2012-07-26 Warsaw Orthopedic, Inc. Interbody containment implant
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