US20040181175A1 - Guidewire - Google Patents

Guidewire Download PDF

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Publication number
US20040181175A1
US20040181175A1 US10755909 US75590904A US2004181175A1 US 20040181175 A1 US20040181175 A1 US 20040181175A1 US 10755909 US10755909 US 10755909 US 75590904 A US75590904 A US 75590904A US 2004181175 A1 US2004181175 A1 US 2004181175A1
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Prior art keywords
core
coil
guidewire
formed
enlargement
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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US10755909
Inventor
Ralph Clayman
Edward Pingleton
Frans Vandenbroek
Ghassan Sakakine
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Applied Medical Resources Corp
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Applied Medical Resources Corp
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/307Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the urinary organs, e.g. urethroscopes, cystoscopes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • A61M2025/09058Basic structures of guide wires
    • A61M2025/09083Basic structures of guide wires having a coil around a core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • A61M2025/09175Guide wires having specific characteristics at the distal tip

Abstract

A urological guidewire includes a core formed of a first metallic material and extending toward an end of the guidewire. A coil having a plurality of convolutions is disposed around the core at the end of the guidewire, the coil being formed of a second metallic material different than the first metallic material. A mechanical interlock is formed to inhibit separation of the different materials forming the coil and the core. The mechanical interlock may include an enlargement at the end of the core and a bonding material fixing the enlargement to the coil. The convolutions may include a penultimate convolution with a first radius of curvature and an ultimate convolution having a second, shorter radius of curvature to form a bridge. In this case, portions of the core can be bent back on themselves and directed over or around the bridge to form the mechanical interlock.

Description

    BACKGROUND OF THE INVENTION
  • 1. Field of the Invention [0001]
  • This invention relates generally to guidewires and, more specifically, to urological guidewires adapted for insertion and instrument guidance through the urological conduit. [0002]
  • 2. Discussion of Related Art [0003]
  • The first step in a typical endoscopic urological procedure is placement of a quidewire into the patient's urological system. When operatively disposed, the guidewire typically extends from outside the patient, through the urethra, the bladder, the ureter, and into the kidney. The guidewire allows a variety of specialized tools, such as catheters and endoscopes, to be repeatedly positioned in the urological system with ease, safety, and efficiency. [0004]
  • Urological guidewires of the past have typically been provided with properties relating to flexibility, lubricity, and stiffness. Each guidewire has tended to emphasize one of these properties along its entire length, in order to provide certain advantages at different points in the procedure. For example, due to the serpentine configuration of a ureter, the initial or “access” guidewire is required to have a high degree of flexibility to facilitate easy insertion. However, once the flexible access guidewire is in place, it is ill-suited for the placement of instruments. By comparison, stiffer guidewires facilitate the insertion of instruments, because they tend to straighten out the anatomy in a way that flexible guidewires cannot. By straightening the anatomy and providing a more rigid guide element, instruments can be more easily inserted over the guidewire to reach an operative site. [0005]
  • In the past, before instrumentation could be inserted into the patient, the flexible access guidewire had to be exchanged for a stiffer, “working” guidewire. This was accomplished by placing an exchange sheath (a small-diameter flexible tube) over the access guidewire and then removing the access guidewire, leaving the sheath in place in the urological system. After the access guidewire was removed from the sheath, the stiffer, working guidewire was then inserted into the exchange sheath and the sheath removed. This left the working guidewire in place of the previous access guidewire. Unfortunately, this four-step procedure was required every time one guidewire was exchanged for another guidewire. [0006]
  • In some cases, the flexible access guidewire was incapable of being fully inserted, typically due to some obstruction such as a urological stone-or stricture in the urological system. Under these circumstances, it became desirable to substitute a “slippery” guidewire for the access guidewire. The slippery guidewire provided a high degree of lubricity, typically due to a specialized hydrophilic coating, which facilitated placement past the obstruction. Again, the four-step exchange procedure was required to insert the slippery guidewire. In some cases, the four-step procedure was required to replace the slippery guidewire, perhaps with the access guidewire, in order to achieve the ultimate, desired position within the urological system. Finally, the four-step replacement procedure would then be required once more to replace the access guidewire with the working guidewire. [0007]
  • Alternatively, in those cases where the slippery guidewire was able to achieve the ultimate, desired position in the urological system, it also presented disadvantages for the placement of instrumentation. Slippery guidewires tend to be so lubricious that they can actually fall out of the urological system, purely due to gravitational forces. Under these circumstances the entire guidewire-placement procedure must be restarted. Accordingly, even with a slippery guidewire in place, it required the four-step, replacement procedure to substitute the working guidewire before the placement of instrumentation could begin. It can be appreciated that in some cases a minimum of three guidewires were needed, along with multiple applications of the four-step procedure for the exchange of the guidewires. [0008]
  • A common method of joining two metals is welding, soldering, or bonding via an adhesive. In the case of a urological guidewire, a metal mandrel, or core, is often joined to a coaxially-oriented metal coil by these methods. These processes are very operator dependent, and if not properly accomplished, can result in separation of the joined components within the patient. [0009]
  • SUMMARY OF THE INVENTION
  • The present invention overcomes these deficiencies of the prior art and provides a guidewire with a highly flexible, kink-resistant tip providing easy access. This tip can be coated with a lubricious, hydrophilic compound which facilitates passing the guidewire beyond stones and obstructions. A central area of the guidewire features a stiff construction which facilitates the passage of instruments over the guidewire. A proximal portion is provided with moderate flexibility which facilitates the retrograde threading of the guidewire into the guidewire channel of an instrument. [0010]
  • The distal floppy tip of the guidewire consists of a kink-resistant tapered Nitinol core which is covered with a small-diameter stainless steel coil. A method for attaching these two dissimilar metals is achieved with a mechanical locking feature. This mechanical lock is stronger than welding, soldering, braising, or gluing. Nevertheless, a small amount of solder or adhesive can be used to cover and encapsulate the mechanical lock. This process reduces the dependency on a welded or glued joint by replacing the joint with a mechanical interlock. The interlock can still be encapsulated by weld, solder, or adhesive, but the majority of the strength of the joint is now provided by the two parent materials. This method is particularly useful in cases where the components to be joined are made of dissimilar metals. The strength of the resulting joint is of significant advantage to the guidewire and greatly increases the safety of the procedure. [0011]
  • In a preferred embodiment, the urological guidewire has three regions of specific flexibility. The distal region includes a floppy distal tip with a very low coefficient of friction making it relatively slippery. A central section of the guidewire is relatively non-slippery, thereby facilitating the passage of instrumentation, while a proximal section is provided with a medium degree of lubricity. Materials such as Nitinol stainless steel, platinum, gold, and silver can be used in the various sections. A mechanical lock forged between dissimilar metals can be encapsulated in urethane, solder, adhesive, or by insert-molding a polymer. [0012]
  • In one aspect, the invention includes a urological guidewire having a distal section with a first flexibility, a first lubricity, and a first length. A central section is also provided, which has a second flexibility, a second lubricity, and a second length. On the side of the central section opposite the distal section, a proximal section has a third flexibility, a third lubricity, and a third length. The third flexibility is greater than the second flexibility, but less than the first flexibility. The second lubricity and the third lubricity are less than the first lubricity. Finally, the first length is greater than the third length and less than the second length. [0013]
  • In another aspect of the invention, the urological guidewire includes a core formed of the first metallic material and extending toward an end of the guidewire. A coil including a plurality of convolutions extends around the core at the end of the guidewire and is formed of a second metallic material different than the first metallic material. A mechanical interlock is formed between the coil and the core to inhibit separation of the coil from the core. This mechanical interlock can include an enlargement having a lateral dimension greater than the diameter of the core at the distal end of the core. A bonding material encapsulates the enlargement and bonds the enlargement to the coil. [0014]
  • The mechanical interlock can also be formed by providing the coil with a penultimate convolution having a first radius, and an ultimate convolution having a second radius less than the first radius to form a bridge. Portions of the core can be bent over or around the bridge to form the mechanical interlock. [0015]
  • In an associated method of manufacture, the enlargement of the core can be mechanically bonded to the coil. Alternatively, the coil can be provided with the bridge and the core can be bent over or around the bridge and fixed to itself to form a mechanical interlock. These and other features and advantages of the invention will be more apparent with a discussion of preferred embodiments and reference to the associated drawings.[0016]
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • FIG. 1A is a side elevation view of a urological catheter having a core and a coil extending between a proximal end and a distal end, with a mechanical interlock formed between the core and coil at the distal end; [0017]
  • FIG. 1B is an enlarged side elevation view of the embodiment of FIG. 1A; [0018]
  • FIG. 2 is an enlarged side elevation view of one embodiment of a mechanical interlock between the core and coil; [0019]
  • FIG. 3 is a side elevation view in axial cross section illustrating a boss crimped around an enlargement at the distal end of the core; and [0020]
  • FIG. 4 is an enlarged perspective view of an additional embodiment of a mechanical interlock formed by bending the core over a bridge of the coil; [0021]
  • FIG. 5 is a radial cross section view of the embodiment illustrated in FIG. 3; [0022]
  • FIG. 6 is a side elevation view of the distal end of a core bent back on itself and fixed to itself by a female; [0023]
  • FIG. 7 is an additional embodiment of the core bent back on itself and fixed to itself with a butt joint; [0024]
  • FIG. 8 is a side elevation view of a further embodiment of the distal end of the core bent back on itself and fixed to itself with a shear joint; and [0025]
  • FIG. 9 is a perspective view of a further embodiment illustrating the core formed around the bridge and at least one revolution. - -[0026]
  • DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS AND BEST MODE OF THE INVENTION
  • A urological guidewire as illustrated in FIG. 1, and designated generally by the reference numeral [0027] 10. The guidewire 10 has an elongate configuration and stems between a proximal end 12 and a distal end 14. The guidewire 10 is adapted for use in accessing distal locations within the urinary tract by inserting the distal end 14 into the urethra of the patient and advancing the distal end 14 to the operative site. Various instruments can then be advanced over the guidewire 10 to perform an operative procedure at the operative site.
  • In the illustrated embodiment, the urological guidewire [0028] 10 includes a distal section 16 with a first flexibility, a first lubricity, and a first length. The central section 18 has a second flexibility, a second lubricity, and a second length. Similarly, a proximal section 21 has a third flexibility, a third lubricity, and a third length. In a preferred embodiment, the first length of the distal section 16 is 14.4 mm and the third length of the proximal section 21 is 5.5 mm. The overall length of this embodiment is 200 cm. As a result, the length of the distal section 16 is greater than the length of the proximal section 21, but less than the length of the central section 18.
  • The flexibility of the various sections [0029] 16, 18, and 21 is defined generally as the ability of that section to be bent back on itself along a radius without kinking. The smaller the radius, the greater the flexibility. By way of example, the flexibility of the distal section 16 is relatively great, in that it can be bent back on itself along a smaller radius than that of the proximal section 21. By comparison, the flexibility of the central section 18 is relatively great, in that it cannot be bent along a radius as small as that of the central section 18 without kinking. Accordingly, the flexibility of the proximal section 21 is less than that of the distal section 16, but greater than that of the central section 18.
  • The lubricity of the various sections [0030] 16, 18, and 21 is based generally on the coefficient of friction which exists between the materials forming the outer surface of the individual sections 16, 18, and 21, and the tissue forming the urinary conduit. Where this coefficient of friction is low, the associated sections 16, 18, and 21 are deemed to have a high lubricity facilitating insertion, but inhibiting retention of the catheter 10 within the urinary tract. In the illustrated embodiment, the proximal section 21 is constructed to have a lubricity less than that of the distal section 16, but greater than that of the central section 18.
  • These characteristics of the present invention provide the urological guidewire [0031] 10 with performance far superior to that of previous guidewires. With the relatively high lubricity in the distal section, guidewire insertion is greatly facilitated; but with the relatively low lubricity in the central section 18, the tension of the guidewire 10 is greatly increased. In the proximal section 21, the medium level of lubricity is provided to facilitate the retrograde insertion of instruments over the guidewire 10.
  • The flexibility of the guidewire [0032] 10 is greatest in the distal section 16 and facilitates initial insertion of the guidewire 10 through the tortuous path of the urinary conduit. Once the distal section 16 is passed, the central section 18 with its reduced flexibility can tend to straighten the urinary canal and otherwise facilitate the insertion of instruments over the guidewire 10. A medium level of flexibility can be maintained in the proximal section 21 only as necessary to facilitate retrograde insertion of the guidewire 10 into the guidechannel of the instrument.
  • In combination, these features facilitate the initial insertion of the guidewire [0033] 10 with the relatively flexible and lubricious distal section 16, and the straightening of the urinary tract with the relatively inflexible central section 18. The guidewire 10 tends to remain in place with the relatively non-lubricious characteristics of the central section 18. With medium levels of flexibility and lubricity in the proximal section 21, the guidewire 10 can be easily inserted into the guidelumen of the instrument. Further insertion of the instrument is facilitated by the relatively high coefficient of friction which maintains the central section 18 in its operative position within the urinary tract.
  • These features are provided in a preferred embodiment with a construction that includes a core [0034] 23 having a distal end 25 and a proximal end 27. In a preferred embodiment, the core 23 is formed of a material having superelastic characteristics such as Nitinol. The core 23 has a constant diameter of 0.032 inches in the central section 18. At the distal end 25, the core 23 is provided with a taper 30, which is about 3 inches in length. The taper 30 reduces the diameter of the core 23 from 0.032 inches at the central section 18 to a diameter of 0.006 inches at a distal tip 32. The tip 32 in the preferred embodiment has a length of about 1.5 inches. In the distal section 16, the taper 30 and the distal tip 32 of the core 23 can be covered by a wire coil 34, which in a preferred embodiment is provided with a hydrophilic coating 36. In a preferred embodiment, the wire forming the coil 34 has a circular cross-section and a diameter of 0.005 inches.
  • This construction of the distal section [0035] 16 is of particular advantage to the guidewire 10, as it provides a high degree of flexibility at the distal end 14. In this preferred embodiment, the distal section 16 can be bent back on itself without kinking along a radius as small as 0.10 inches.
  • A similar construction can be provided in the proximal section [0036] 21, wherein the core 23 includes a taper 38 from the central section diameter of 0.032 inches to a diameter of about 0.010 inches. A flat-wire coil 41 can be formed over the taper 38 in the proximal section 21. Both of the wire coils 36 and 41 are preferably formed of a stainless steel.
  • In the guidewire constructions of the prior art, the core material is typically the same as the material forming the wire coils. As a consequence, the two materials are easily bonded chemically, using chemical bonding methods that attach the molecules of the core to the molecules of the coil. When the materials forming these two elements are dissimilar, chemical bonding may not be sufficiently reliable to ensure that the core [0037] 23 and coil 34 are maintained in a fixed relationship. Failure to maintain this relationship can result in undesirable separation of the coil 34 from the core 23.
  • In accordance with the present invention, a mechanical bond is formed between the core [0038] 23 and coil 34 to ensure that there is no separation between these structural elements. In accordance with the present invention, a mechanical interlock 43 is provided between the distal tip 32 of the core 23 at the distal end of the coil 36. This mechanical interlock 43 provides for a mechanical attachment of the core 23 to the coil 34 without the need for any chemical bond. This mechanical interlock 43 can be of the type illustrated in the axial cross-section view of FIG. 2. The concept of this embodiment requires a formation of an enlargement 45 at the distal tip 32 of the core 23. This enlargement 45 in the illustrated embodiment is formed by bending the tip 32 back on itself to form a hook 46. Whether provided in the hook configuration or any other shape, the enlargement 45 typically has a lateral or radial dimension that is greater than the diameter of the distal tip 32. This enlargement 45 can then be encased in a material capable of being set to form a plug 50 enclosing the enlargement 45 (such as the hook 47) and portions of the coil 34, as illustrated in FIG. 2. The plug 50 engages the enlargement 45 as well as the coil 34 to mechanically inhibit their separation. By providing the enlargement 45, the mechanical bond between the plug 50 and the core 23 is greatly enhanced.
  • The material forming the plug [0039] 50 can have a variety of characteristics, each offering some advantage in a particular embodiment of the invention. For example, the plug 50 can be formed from a solder such as silver solder, or from an adhesive such as an epoxy.
  • Another embodiment of the mechanical interlock [0040] 43 is illustrated in FIG. 3, wherein the enlargement 45 is provided in the shape of a sphere 52 and the mechanical interlock 43 is provided by a stainless steel boss 53, which is crimped over the sphere 52 and the distal end of the wire coil 34. This boss 53, which is typically formed of stainless steel, provides the mechanical interlock, not only with the sphere 52, but also with the wire coil 34, so that these two elements are held in a fixed, non-separable relationship.
  • Another embodiment of the mechanical interlock [0041] 43 is illustrated in FIGS. 4-8. In this embodiment, the wire coil 34 is formed with a plurality of convolutions 54, including an ultimate convolution 56 and a penultimate convolution 58. In this embodiment, the convolutions 54 have a generally constant diameter, except for the ultimate convolution 56. For example, with reference to FIG. 5, it can be seen that the convolutions 57 have a diameter D1, except for the ultimate convolution 56, which has a diameter D2 less than D1. With this lesser diameter D2, the distal tip 32 of the wire core forms a bridge 61 in the ultimate convolution 56, which extends across the penultimate convolution 58. With the coil 34 in this configuration, the distal tip 32 of the core 23 can be bent over the bridge 61 to form a portion of the mechanical interlock 43. This also forms the enlargement 45 in the shape of the hook 47, which can then be encased in the plug 50 to further enhance the properties of the mechanical interlock 43.
  • In order to even further enhance the properties of the mechanical interlock [0042] 43, the distal end 32 of the core 23, which is bent back on itself to form the hook 47, can be attached to itself, for example, as illustrated in FIGS. 6-8. More specifically, the distal tip 32 can be bent back on itself and attached to the core 23 by mechanical means such as a metal or plastic ferrule, or a clip 63. Alternatively, the distal tip 32 can be laser welded, for example, to form a butt joint 67, as illustrated in FIG. 7, or a shear joint 70, as shown in FIG. 8. In a further embodiment illustrated in FIG. 9, the distal tip 34 is bent back on itself and then fed through the plurality of convolutions 54 to further enhance the characteristics of the mechanical interlock 43.
  • In still a further embodiment of the invention, the distal tip [0043] 32 of the core 23 can be wrapped around the bridge 61 in one or more revolutions designated by the reference numeral 72 in FIG. 9 This further enhances the mechanical attachment of the core 23 to the coil 34 and greatly increases the properties of the mechanical interlock 43.
  • Having reviewed certain preferred embodiments of the invention, many modifications will now be apparent and of particular advantage in other embodiments of the concept. For example, it will be noted that the bridge [0044] 61 can generally have any length; however, it may be desirable for the bridge 61 to have a length greater than the diameter D1 of the penultimate convolution 58. This ensures that the bridge 61 is supported at both of its ends by the penultimate convolution 58. It will also be noted that the bridge 61 can be formed generally in any of the convolutions 54, not just the ultimate convolution 56, in order to facilitate the mechanical interlock between the coil 34 and the core 23.
  • Although the foregoing embodiments and methods of operation have been described in significant detail, it will be apparent that this invention is a concept which may be otherwise embodied. As a result, one is cautioned not to determine the nature of the concept solely with reference to the described embodiments and method steps, but rather with particular reference to the following claims. [0045]

Claims (15)

  1. 1. A urological guidewire, comprising:
    a core formed of a first metallic material and extending toward an end of the guidewire;
    a coil including a plurality of convolutions extending around the core at the end of the guidewire, the coil being formed of a second metallic material different than the first metallic material; and
    a mechanical interlock formed between the coil and the core to inhibit separation of the coil from the core.
  2. 2. The urological guidewire recited in claim 1 wherein the core has a distal end with a diameter and a mechanical interlock, comprising:
    an enlargement having a fixed relationship with the end of the core and having a lateral dimension greater than the diameter of the core at the distal end of the core; and
    a bonding material fixing the enlargement to the coil to mechanically bond the core to the coil.
  3. 3. The urological guidewire recited in claim 2, wherein the enlargement is formed integral with the core and comprises a hook formed at the distal end of the core.
  4. 4. The urological guidewire recited in claim 2, further comprising:
    a penultimate convolution included among the plurality of convolutions, the penultimate convolution having a first radius of curvature; and
    an ultimate convolution included among the plurality of convolutions, the ultimate convolution having a second radius of curvature less than the first radius of curvature to form a bridge across the penultimate convolution.
  5. 5. The urological guidewire recited in claim 4 wherein the mechanical interlock comprises:
    portions of the core extending at least partially around the bridge of the ultimate convolution to mechanically interlock the core and the coil of the guidewire.
  6. 6. The urological guidewire recited in claim 5 wherein the portions of the core include at least one revolution of the core extending around the bridge of the coil.
  7. 7. The urological guidewire recited in claim 6, wherein:
    the distal end of the core is bent back on itself; and
    the distal end of the core is attached to itself to fix the distal end of the core around the bridge of the coil.
  8. 8. A method for manufacturing a guidewire having a core and a coil spiraled in a plurality of convolutions around the core, comprising the steps of:
    forming the core of a first metallic material;
    forming the coil of a second metallic :material different than the first metallic material; and
    mechanically interlocking the coil and the core.
  9. 9. The method recited in claim 8 wherein the mechanical interlocking step includes the steps of:
    providing an enlargement; and
    mechanically bonding the enlargement to the coil.
  10. 10. The method recited in claim 9 wherein the bonding step includes the steps of:
    bonding the enlargement to the coil by one of welding, soldering, and adhering the enlargement to the coil.
  11. 11. The method recited in claim 8 further comprising the steps of:
    providing the coil with a convolution forming a bridge; and
    during the mechanical interlocking step, bending the core over the bridge.
  12. 12. The method recited in claim 11 wherein the bending step includes the step of bending the core in at least one revolution around the bridge.
  13. 13. The method recited in claim 12 further comprising the step of:
    after the bending step, fixing the core to itself.
  14. 14. The urological guidewire, comprising:
    a distal section having a first flexibility, a first lubricity, and a first length;
    a central section having a second flexibility, a second lubricity, and a second length;
    a proximate section having a third flexibility, a third lubricity, and a third length;
    the third flexibility being greater than the second flexibility and less than the first flexibility;
    the second lubricity and the third lubricity being less than the first lubricity; and
    the first length being greater than the third length and less than the second length.
  15. 15. The urological guidewire, comprising:
    a core formed of a first metallic material and extending toward an end to the guidewire;
    a coil including a plurality of convolutions extending around the core at the distal end of the guidewire, the coil being formed of a second metallic material different than the first metallic material; and
    a mechanical interlock formed between the coil and the core to inhibit separation of the coil from the core.
US10755909 1999-04-30 2004-01-13 Guidewire Abandoned US20040181175A1 (en)

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US13205599 true 1999-04-30 1999-04-30
PCT/US2000/011586 WO2000065987A1 (en) 1999-04-30 2000-04-28 Guidewire
US09947071 US6716183B2 (en) 1999-04-30 2001-09-05 Guidewire
US10755909 US20040181175A1 (en) 1999-04-30 2004-01-13 Guidewire

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US10755909 US20040181175A1 (en) 1999-04-30 2004-01-13 Guidewire

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Cited By (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060106407A1 (en) * 2004-11-17 2006-05-18 Mcguckin James F Jr Rotational thrombectomy wire
US20090227900A1 (en) * 2008-03-10 2009-09-10 Isaac Kim Corewire design and construction for medical devices
US8080000B2 (en) 2004-04-21 2011-12-20 Acclarent, Inc. Methods and apparatus for treating disorders of the ear nose and throat
US8088101B2 (en) 2004-04-21 2012-01-03 Acclarent, Inc. Devices, systems and methods for treating disorders of the ear, nose and throat
US8100933B2 (en) 2002-09-30 2012-01-24 Acclarent, Inc. Method for treating obstructed paranasal frontal sinuses
US8114062B2 (en) 2004-04-21 2012-02-14 Acclarent, Inc. Devices and methods for delivering therapeutic substances for the treatment of sinusitis and other disorders
US8114113B2 (en) 2005-09-23 2012-02-14 Acclarent, Inc. Multi-conduit balloon catheter
US8118757B2 (en) 2007-04-30 2012-02-21 Acclarent, Inc. Methods and devices for ostium measurement
US8142422B2 (en) 2004-04-21 2012-03-27 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, nose and/or throat
US8146400B2 (en) 2004-04-21 2012-04-03 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US8172828B2 (en) 2004-04-21 2012-05-08 Acclarent, Inc. Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures
US8190389B2 (en) 2006-05-17 2012-05-29 Acclarent, Inc. Adapter for attaching electromagnetic image guidance components to a medical device
US20120197159A1 (en) * 2011-01-28 2012-08-02 Asahi Intecc Co., Ltd. Guidewire
US20130006149A1 (en) * 2011-06-29 2013-01-03 Abbott Cardiovascular Systems Guide Wire Device Including a Solderable Linear Elastic Nickel-Titanium Distal End Section and Methods Of Preparation Therefor
US8388642B2 (en) 2005-01-18 2013-03-05 Acclarent, Inc. Implantable devices and methods for treating sinusitis and other disorders
US8414473B2 (en) 2004-04-21 2013-04-09 Acclarent, Inc. Methods and apparatus for treating disorders of the ear nose and throat
US8435290B2 (en) 2009-03-31 2013-05-07 Acclarent, Inc. System and method for treatment of non-ventilating middle ear by providing a gas pathway through the nasopharynx
US8439687B1 (en) 2006-12-29 2013-05-14 Acclarent, Inc. Apparatus and method for simulated insertion and positioning of guidewares and other interventional devices
US8485199B2 (en) 2007-05-08 2013-07-16 Acclarent, Inc. Methods and devices for protecting nasal turbinate during surgery
US8663259B2 (en) 2010-05-13 2014-03-04 Rex Medical L.P. Rotational thrombectomy wire
US8702626B1 (en) 2004-04-21 2014-04-22 Acclarent, Inc. Guidewires for performing image guided procedures
US8715169B2 (en) 2004-04-21 2014-05-06 Acclarent, Inc. Devices, systems and methods useable for treating sinusitis
US8740929B2 (en) 2001-02-06 2014-06-03 Acclarent, Inc. Spacing device for releasing active substances in the paranasal sinus
US8747389B2 (en) 2004-04-21 2014-06-10 Acclarent, Inc. Systems for treating disorders of the ear, nose and throat
US8764729B2 (en) 2004-04-21 2014-07-01 Acclarent, Inc. Frontal sinus spacer
US8764779B2 (en) 2010-05-13 2014-07-01 Rex Medical, L.P. Rotational thrombectomy wire
US8864787B2 (en) 2004-04-21 2014-10-21 Acclarent, Inc. Ethmoidotomy system and implantable spacer devices having therapeutic substance delivery capability for treatment of paranasal sinusitis
US8894614B2 (en) 2004-04-21 2014-11-25 Acclarent, Inc. Devices, systems and methods useable for treating frontal sinusitis
US8932276B1 (en) 2004-04-21 2015-01-13 Acclarent, Inc. Shapeable guide catheters and related methods
US8951225B2 (en) 2005-06-10 2015-02-10 Acclarent, Inc. Catheters with non-removable guide members useable for treatment of sinusitis
US8979888B2 (en) 2008-07-30 2015-03-17 Acclarent, Inc. Paranasal ostium finder devices and methods
US9023070B2 (en) 2010-05-13 2015-05-05 Rex Medical, L.P. Rotational thrombectomy wire coupler
US9039680B2 (en) 2004-08-04 2015-05-26 Acclarent, Inc. Implantable devices and methods for delivering drugs and other substances to treat sinusitis and other disorders
US9072626B2 (en) 2009-03-31 2015-07-07 Acclarent, Inc. System and method for treatment of non-ventilating middle ear by providing a gas pathway through the nasopharynx
US9089258B2 (en) 2004-04-21 2015-07-28 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US9101384B2 (en) 2004-04-21 2015-08-11 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, Nose and/or throat
US9107574B2 (en) 2004-04-21 2015-08-18 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US9155492B2 (en) 2010-09-24 2015-10-13 Acclarent, Inc. Sinus illumination lightwire device
US9265407B2 (en) 2004-04-21 2016-02-23 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US9351750B2 (en) 2004-04-21 2016-05-31 Acclarent, Inc. Devices and methods for treating maxillary sinus disease
US9399121B2 (en) 2004-04-21 2016-07-26 Acclarent, Inc. Systems and methods for transnasal dilation of passageways in the ear, nose or throat
US9433437B2 (en) 2013-03-15 2016-09-06 Acclarent, Inc. Apparatus and method for treatment of ethmoid sinusitis
US9468362B2 (en) 2004-04-21 2016-10-18 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US9629684B2 (en) 2013-03-15 2017-04-25 Acclarent, Inc. Apparatus and method for treatment of ethmoid sinusitis
US9795406B2 (en) 2010-05-13 2017-10-24 Rex Medical, L.P. Rotational thrombectomy wire
US9820688B2 (en) 2006-09-15 2017-11-21 Acclarent, Inc. Sinus illumination lightwire device

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000065987A1 (en) * 1999-04-30 2000-11-09 Applied Medical Resources Corporation Guidewire
US20040127820A1 (en) * 2001-09-05 2004-07-01 Clayman Ralph V. Guidewire
WO2003000331A1 (en) * 2001-06-21 2003-01-03 Jomed Gmbh Methods and apparatus for crossing a heart valve
JP2005528126A (en) * 2001-10-05 2005-09-22 ボストン サイエンティフィック リミテッド Composite guidewire
JP4028245B2 (en) * 2002-01-28 2007-12-26 テルモ株式会社 Guide wire
US8177790B2 (en) * 2002-04-20 2012-05-15 Friedhelm Brassel Medical retriever
WO2004018031A3 (en) * 2002-08-22 2004-04-15 Cook Inc Guide wire
US20070179518A1 (en) * 2006-02-02 2007-08-02 Becker Bruce B Balloon Catheters and Methods for Treating Paranasal Sinuses
US7758592B2 (en) 2002-12-02 2010-07-20 Wilson-Cook Medical Inc. Loop tip wire guide
EP1572282B1 (en) * 2002-12-02 2014-07-16 Cook Medical Technologies LLC Loop tip wire guide
JP4650901B2 (en) * 2003-04-03 2011-03-16 エシコン・エンド−サージェリィ・インコーポレイテッドEthicon Endo−Surgery,Inc. Guide wire having a curved segment
US20040225232A1 (en) * 2003-05-09 2004-11-11 Radi Medical Systems Ab Sensor guide wire
US20040267163A1 (en) * 2003-06-03 2004-12-30 Opie John C. Medical guide wires
US7237313B2 (en) * 2003-12-05 2007-07-03 Boston Scientific Scimed, Inc. Elongated medical device for intracorporal use
US20070208252A1 (en) * 2004-04-21 2007-09-06 Acclarent, Inc. Systems and methods for performing image guided procedures within the ear, nose, throat and paranasal sinuses
WO2005113051A3 (en) 2004-05-14 2007-07-12 Gregory J Bakos Medical instrument having a medical guidewire
US7758564B2 (en) 2004-05-14 2010-07-20 Ethicon Endo-Surgery, Inc. Medical instrument having a catheter and a medical guidewire
US7615022B2 (en) * 2004-07-22 2009-11-10 Nordt Development Co., Llc Potentiating support with alignment opening for joint protuberance
EP1793886B1 (en) * 2004-09-30 2008-11-26 Wilson-Cook Medical Inc. Loop tip wire guide
DE602005012302D1 (en) * 2004-09-30 2009-02-26 Wilson Cook Medical Inc Steerable guidewire from the loop Type
US8070693B2 (en) * 2004-09-30 2011-12-06 Cook Medical Technologies Llc Articulating steerable wire guide
US8221348B2 (en) * 2005-07-07 2012-07-17 St. Jude Medical, Cardiology Division, Inc. Embolic protection device and methods of use
WO2007035305A1 (en) * 2005-09-15 2007-03-29 Wilson-Cook Medical Inc. Multiple stage wire guide
US8002714B2 (en) 2006-08-17 2011-08-23 Ethicon Endo-Surgery, Inc. Guidewire structure including a medical guidewire and method for using a medical instrument
US8715205B2 (en) * 2006-08-25 2014-05-06 Cook Medical Tecnologies Llc Loop tip wire guide
US8852223B2 (en) * 2007-04-06 2014-10-07 Cordis Corporation Fixed wire dilatation catheter with an elongateable distal end
US20090030409A1 (en) * 2007-07-27 2009-01-29 Eric Goldfarb Methods and devices for facilitating visualization in a surgical environment
GB0902339D0 (en) * 2009-02-12 2009-04-01 St Georges Healthcare Nhs Trus Percutaneous guidewire
US20110160740A1 (en) * 2009-12-28 2011-06-30 Acclarent, Inc. Tissue Removal in The Paranasal Sinus and Nasal Cavity
JP5733794B2 (en) * 2011-05-10 2015-06-10 朝日インテック株式会社 Medical guide wire
US9918705B2 (en) 2016-07-07 2018-03-20 Brian Giles Medical devices with distal control

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5421349A (en) * 1994-06-16 1995-06-06 Cordis Corporation Atraumatic proximal guidewire end
US5666969A (en) * 1994-05-18 1997-09-16 Scimed Life Systems, Inc. Guidewire having multiple radioscopic coils
US5924998A (en) * 1997-03-06 1999-07-20 Scimed Life System, Inc. Guide wire with hydrophilically coated tip
US6716183B2 (en) * 1999-04-30 2004-04-06 Applied Medical Resources Corporation Guidewire
US20040127820A1 (en) * 2001-09-05 2004-07-01 Clayman Ralph V. Guidewire

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3612058A (en) 1968-04-17 1971-10-12 Electro Catheter Corp Catheter stylets
US3625200A (en) * 1969-08-26 1971-12-07 Us Catheter & Instr Corp Controlled curvable tip member
US4748986A (en) * 1985-11-26 1988-06-07 Advanced Cardiovascular Systems, Inc. Floppy guide wire with opaque tip
US4682607A (en) 1985-12-02 1987-07-28 Vlv Associates Wire guide
US4884579A (en) 1988-04-18 1989-12-05 Target Therapeutics Catheter guide wire
US5067489A (en) 1988-08-16 1991-11-26 Flexmedics Corporation Flexible guide with safety tip
US5001825A (en) * 1988-11-03 1991-03-26 Cordis Corporation Catheter guidewire fabrication method
CA2019063E (en) 1989-06-29 2000-01-04 Brian L. Bates Hydrophilically coated flexible wire guide
US5238004A (en) 1990-04-10 1993-08-24 Boston Scientific Corporation High elongation linear elastic guidewire
DK146790D0 (en) 1990-06-15 1990-06-15 Meadox Surgimed As Method for producing an at fertilization friktionsnedsaettende paperboard and medical instrument with a friktionsnedsaettende COATED
US5433200A (en) 1990-07-09 1995-07-18 Lake Region Manufacturing, Inc. Low profile, coated, steerable guide wire
US5228453A (en) 1991-05-07 1993-07-20 Target Therapeutics, Inc. Catheter guide wire
US5443907A (en) 1991-06-18 1995-08-22 Scimed Life Systems, Inc. Coating for medical insertion guides
CA2068584C (en) 1991-06-18 1997-04-22 Paul H. Burmeister Intravascular guide wire and method for manufacture thereof
US5333620A (en) * 1991-10-30 1994-08-02 C. R. Bard, Inc. High performance plastic coated medical guidewire
US5217026A (en) 1992-04-06 1993-06-08 Kingston Technologies, Inc. Guidewires with lubricious surface and method of their production
US5769796A (en) * 1993-05-11 1998-06-23 Target Therapeutics, Inc. Super-elastic composite guidewire
US5772609A (en) 1993-05-11 1998-06-30 Target Therapeutics, Inc. Guidewire with variable flexibility due to polymeric coatings
US5749837A (en) 1993-05-11 1998-05-12 Target Therapeutics, Inc. Enhanced lubricity guidewire
US5363847A (en) 1993-10-27 1994-11-15 Cordis Corporation Guidewire having double distal portions
US5720300A (en) 1993-11-10 1998-02-24 C. R. Bard, Inc. High performance wires for use in medical devices and alloys therefor
US5497782A (en) 1994-04-28 1996-03-12 Medtronic, Inc. Lockable guidewire
US5722424A (en) 1995-09-29 1998-03-03 Target Therapeutics, Inc. Multi-coating stainless steel guidewire
US5840046A (en) 1996-06-21 1998-11-24 Medtronic, Inc. Guidewire having hydrophilic coating
US5827201A (en) 1996-07-26 1998-10-27 Target Therapeutics, Inc. Micro-braided guidewire
US5876356A (en) 1997-04-02 1999-03-02 Cordis Corporation Superelastic guidewire with a shapeable tip

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5666969A (en) * 1994-05-18 1997-09-16 Scimed Life Systems, Inc. Guidewire having multiple radioscopic coils
US5421349A (en) * 1994-06-16 1995-06-06 Cordis Corporation Atraumatic proximal guidewire end
US5924998A (en) * 1997-03-06 1999-07-20 Scimed Life System, Inc. Guide wire with hydrophilically coated tip
US6716183B2 (en) * 1999-04-30 2004-04-06 Applied Medical Resources Corporation Guidewire
US20040127820A1 (en) * 2001-09-05 2004-07-01 Clayman Ralph V. Guidewire

Cited By (103)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8740929B2 (en) 2001-02-06 2014-06-03 Acclarent, Inc. Spacing device for releasing active substances in the paranasal sinus
US8100933B2 (en) 2002-09-30 2012-01-24 Acclarent, Inc. Method for treating obstructed paranasal frontal sinuses
US8764786B2 (en) 2002-09-30 2014-07-01 Acclarent, Inc. Balloon catheters and methods for treating paranasal sinuses
US9457175B2 (en) 2002-09-30 2016-10-04 Acclarent, Inc. Balloon catheters and methods for treating paranasal sinuses
US8317816B2 (en) 2002-09-30 2012-11-27 Acclarent, Inc. Balloon catheters and methods for treating paranasal sinuses
US8172828B2 (en) 2004-04-21 2012-05-08 Acclarent, Inc. Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures
US8088101B2 (en) 2004-04-21 2012-01-03 Acclarent, Inc. Devices, systems and methods for treating disorders of the ear, nose and throat
US8090433B2 (en) 2004-04-21 2012-01-03 Acclarent, Inc. Methods and apparatus for treating disorders of the ear nose and throat
US8114062B2 (en) 2004-04-21 2012-02-14 Acclarent, Inc. Devices and methods for delivering therapeutic substances for the treatment of sinusitis and other disorders
US10098652B2 (en) 2004-04-21 2018-10-16 Acclarent, Inc. Systems and methods for transnasal dilation of passageways in the ear, nose or throat
US10034682B2 (en) 2004-04-21 2018-07-31 Acclarent, Inc. Devices, systems and methods useable for treating frontal sinusitis
US8123722B2 (en) 2004-04-21 2012-02-28 Acclarent, Inc. Devices, systems and methods for treating disorders of the ear, nose and throat
US8142422B2 (en) 2004-04-21 2012-03-27 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, nose and/or throat
US8146400B2 (en) 2004-04-21 2012-04-03 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US9167961B2 (en) 2004-04-21 2015-10-27 Acclarent, Inc. Methods and apparatus for treating disorders of the ear nose and throat
US9826999B2 (en) 2004-04-21 2017-11-28 Acclarent, Inc. Methods and apparatus for treating disorders of the ear nose and throat
US9649477B2 (en) 2004-04-21 2017-05-16 Acclarent, Inc. Frontal sinus spacer
US9610428B2 (en) 2004-04-21 2017-04-04 Acclarent, Inc. Devices, systems and methods useable for treating frontal sinusitis
US8080000B2 (en) 2004-04-21 2011-12-20 Acclarent, Inc. Methods and apparatus for treating disorders of the ear nose and throat
US9554691B2 (en) 2004-04-21 2017-01-31 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US9220879B2 (en) 2004-04-21 2015-12-29 Acclarent, Inc. Devices, systems and methods useable for treating sinusitis
US8414473B2 (en) 2004-04-21 2013-04-09 Acclarent, Inc. Methods and apparatus for treating disorders of the ear nose and throat
US8425457B2 (en) 2004-04-21 2013-04-23 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitus and other disorder of the ears, nose and/or throat
US9468362B2 (en) 2004-04-21 2016-10-18 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US9107574B2 (en) 2004-04-21 2015-08-18 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US8961398B2 (en) 2004-04-21 2015-02-24 Acclarent, Inc. Methods and apparatus for treating disorders of the ear, nose and throat
US9399121B2 (en) 2004-04-21 2016-07-26 Acclarent, Inc. Systems and methods for transnasal dilation of passageways in the ear, nose or throat
US9370649B2 (en) 2004-04-21 2016-06-21 Acclarent, Inc. Devices, systems and methods useable for treating sinusitis
US8702626B1 (en) 2004-04-21 2014-04-22 Acclarent, Inc. Guidewires for performing image guided procedures
US8715169B2 (en) 2004-04-21 2014-05-06 Acclarent, Inc. Devices, systems and methods useable for treating sinusitis
US9241834B2 (en) 2004-04-21 2016-01-26 Acclarent, Inc. Devices, systems and methods for treating disorders of the ear, nose and throat
US9101384B2 (en) 2004-04-21 2015-08-11 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, Nose and/or throat
US8747389B2 (en) 2004-04-21 2014-06-10 Acclarent, Inc. Systems for treating disorders of the ear, nose and throat
US9351750B2 (en) 2004-04-21 2016-05-31 Acclarent, Inc. Devices and methods for treating maxillary sinus disease
US9055965B2 (en) 2004-04-21 2015-06-16 Acclarent, Inc. Devices, systems and methods useable for treating sinusitis
US8764729B2 (en) 2004-04-21 2014-07-01 Acclarent, Inc. Frontal sinus spacer
US8764726B2 (en) 2004-04-21 2014-07-01 Acclarent, Inc. Devices, systems and methods useable for treating sinusitis
US8764709B2 (en) 2004-04-21 2014-07-01 Acclarent, Inc. Devices, systems and methods for treating disorders of the ear, nose and throat
US9265407B2 (en) 2004-04-21 2016-02-23 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US8777926B2 (en) 2004-04-21 2014-07-15 Acclarent, Inc. Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasel or paranasal structures
US8828041B2 (en) 2004-04-21 2014-09-09 Acclarent, Inc. Devices, systems and methods useable for treating sinusitis
US8852143B2 (en) 2004-04-21 2014-10-07 Acclarent, Inc. Devices, systems and methods for treating disorders of the ear, nose and throat
US8858586B2 (en) 2004-04-21 2014-10-14 Acclarent, Inc. Methods for enlarging ostia of paranasal sinuses
US8864787B2 (en) 2004-04-21 2014-10-21 Acclarent, Inc. Ethmoidotomy system and implantable spacer devices having therapeutic substance delivery capability for treatment of paranasal sinusitis
US8870893B2 (en) 2004-04-21 2014-10-28 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, nose and/or throat
US8894614B2 (en) 2004-04-21 2014-11-25 Acclarent, Inc. Devices, systems and methods useable for treating frontal sinusitis
US8905922B2 (en) 2004-04-21 2014-12-09 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, nose and/or throat
US8932276B1 (en) 2004-04-21 2015-01-13 Acclarent, Inc. Shapeable guide catheters and related methods
US8945088B2 (en) 2004-04-21 2015-02-03 Acclarent, Inc. Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures
US8721591B2 (en) 2004-04-21 2014-05-13 Acclarent, Inc. Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures
US8961495B2 (en) 2004-04-21 2015-02-24 Acclarent, Inc. Devices, systems and methods for treating disorders of the ear, nose and throat
US9089258B2 (en) 2004-04-21 2015-07-28 Acclarent, Inc. Endoscopic methods and devices for transnasal procedures
US9084876B2 (en) 2004-08-04 2015-07-21 Acclarent, Inc. Implantable devices and methods for delivering drugs and other substances to treat sinusitis and other disorders
US9039680B2 (en) 2004-08-04 2015-05-26 Acclarent, Inc. Implantable devices and methods for delivering drugs and other substances to treat sinusitis and other disorders
US9039657B2 (en) 2004-08-04 2015-05-26 Acclarent, Inc. Implantable devices and methods for delivering drugs and other substances to treat sinusitis and other disorders
US9474543B2 (en) 2004-11-17 2016-10-25 Argon Medical Devices, Inc. Rotational thrombectomy wire
US8062317B2 (en) 2004-11-17 2011-11-22 Rex Medical, L.P. Rotational thrombectomy wire
US7819887B2 (en) 2004-11-17 2010-10-26 Rex Medical, L.P. Rotational thrombectomy wire
US10117671B2 (en) 2004-11-17 2018-11-06 Argon Medical Devices Inc. Rotational thrombectomy device
US8465511B2 (en) 2004-11-17 2013-06-18 Rex Medical, L.P. Rotational thrombectomy wire
US20060106407A1 (en) * 2004-11-17 2006-05-18 Mcguckin James F Jr Rotational thrombectomy wire
US8388642B2 (en) 2005-01-18 2013-03-05 Acclarent, Inc. Implantable devices and methods for treating sinusitis and other disorders
US9308361B2 (en) 2005-01-18 2016-04-12 Acclarent, Inc. Implantable devices and methods for treating sinusitis and other disorders
US10124154B2 (en) 2005-06-10 2018-11-13 Acclarent, Inc. Catheters with non-removable guide members useable for treatment of sinusitis
US8951225B2 (en) 2005-06-10 2015-02-10 Acclarent, Inc. Catheters with non-removable guide members useable for treatment of sinusitis
US9050440B2 (en) 2005-09-23 2015-06-09 Acclarent, Inc. Multi-conduit balloon catheter
US8114113B2 (en) 2005-09-23 2012-02-14 Acclarent, Inc. Multi-conduit balloon catheter
US9999752B2 (en) 2005-09-23 2018-06-19 Acclarent, Inc. Multi-conduit balloon catheter
US8968269B2 (en) 2005-09-23 2015-03-03 Acclarent, Inc. Multi-conduit balloon catheter
US9629656B2 (en) 2006-05-17 2017-04-25 Acclarent, Inc. Adapter for attaching electromagnetic image guidance components to a medical device
US9198736B2 (en) 2006-05-17 2015-12-01 Acclarent, Inc. Adapter for attaching electromagnetic image guidance components to a medical device
US8190389B2 (en) 2006-05-17 2012-05-29 Acclarent, Inc. Adapter for attaching electromagnetic image guidance components to a medical device
US9179823B2 (en) 2006-09-15 2015-11-10 Acclarent, Inc. Methods and devices for facilitating visualization in a surgical environment
US9603506B2 (en) 2006-09-15 2017-03-28 Acclarent, Inc. Methods and devices for facilitating visualization in a surgical environment
US9820688B2 (en) 2006-09-15 2017-11-21 Acclarent, Inc. Sinus illumination lightwire device
US9572480B2 (en) 2006-09-15 2017-02-21 Acclarent, Inc. Methods and devices for facilitating visualization in a surgical environment
US8439687B1 (en) 2006-12-29 2013-05-14 Acclarent, Inc. Apparatus and method for simulated insertion and positioning of guidewares and other interventional devices
US9615775B2 (en) 2007-04-30 2017-04-11 Acclarent, Inc. Methods and devices for ostium measurements
US8118757B2 (en) 2007-04-30 2012-02-21 Acclarent, Inc. Methods and devices for ostium measurement
US8485199B2 (en) 2007-05-08 2013-07-16 Acclarent, Inc. Methods and devices for protecting nasal turbinate during surgery
US9463068B2 (en) 2007-05-08 2016-10-11 Acclarent, Inc. Methods and devices for protecting nasal turbinates
US20090227900A1 (en) * 2008-03-10 2009-09-10 Isaac Kim Corewire design and construction for medical devices
US9861793B2 (en) 2008-03-10 2018-01-09 Acclarent, Inc. Corewire design and construction for medical devices
US8182432B2 (en) 2008-03-10 2012-05-22 Acclarent, Inc. Corewire design and construction for medical devices
US9750401B2 (en) 2008-07-30 2017-09-05 Acclarent, Inc. Paranasal ostium finder devices and methods
US8979888B2 (en) 2008-07-30 2015-03-17 Acclarent, Inc. Paranasal ostium finder devices and methods
US8435290B2 (en) 2009-03-31 2013-05-07 Acclarent, Inc. System and method for treatment of non-ventilating middle ear by providing a gas pathway through the nasopharynx
US9636258B2 (en) 2009-03-31 2017-05-02 Acclarent, Inc. System and method for treatment of non-ventilating middle ear by providing a gas pathway through the nasopharynx
US9072626B2 (en) 2009-03-31 2015-07-07 Acclarent, Inc. System and method for treatment of non-ventilating middle ear by providing a gas pathway through the nasopharynx
US10064645B2 (en) 2010-05-13 2018-09-04 Rex Medical, L.P. Rotational thrombectomy wire
US9282992B2 (en) 2010-05-13 2016-03-15 Rex Medical, L.P. Rotational thrombectomy wire
US9023070B2 (en) 2010-05-13 2015-05-05 Rex Medical, L.P. Rotational thrombectomy wire coupler
US8663259B2 (en) 2010-05-13 2014-03-04 Rex Medical L.P. Rotational thrombectomy wire
US9795406B2 (en) 2010-05-13 2017-10-24 Rex Medical, L.P. Rotational thrombectomy wire
US8764779B2 (en) 2010-05-13 2014-07-01 Rex Medical, L.P. Rotational thrombectomy wire
US9700346B2 (en) 2010-05-13 2017-07-11 Rex Medical, L.P. Rotational thrombectomy wire
US9155492B2 (en) 2010-09-24 2015-10-13 Acclarent, Inc. Sinus illumination lightwire device
US8758269B2 (en) * 2011-01-28 2014-06-24 Asahi Intecc Co., Ltd. Guidewire
US20120197159A1 (en) * 2011-01-28 2012-08-02 Asahi Intecc Co., Ltd. Guidewire
US20130006149A1 (en) * 2011-06-29 2013-01-03 Abbott Cardiovascular Systems Guide Wire Device Including a Solderable Linear Elastic Nickel-Titanium Distal End Section and Methods Of Preparation Therefor
US9724494B2 (en) * 2011-06-29 2017-08-08 Abbott Cardiovascular Systems, Inc. Guide wire device including a solderable linear elastic nickel-titanium distal end section and methods of preparation therefor
US9629684B2 (en) 2013-03-15 2017-04-25 Acclarent, Inc. Apparatus and method for treatment of ethmoid sinusitis
US9433437B2 (en) 2013-03-15 2016-09-06 Acclarent, Inc. Apparatus and method for treatment of ethmoid sinusitis

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US20020010426A1 (en) 2002-01-24 application

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