US20020103512A1 - Adaptive method and apparatus for forecasting and controlling neurological disturbances under a multi-level control - Google Patents

Adaptive method and apparatus for forecasting and controlling neurological disturbances under a multi-level control Download PDF

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US20020103512A1
US20020103512A1 US09/735,364 US73536400A US2002103512A1 US 20020103512 A1 US20020103512 A1 US 20020103512A1 US 73536400 A US73536400 A US 73536400A US 2002103512 A1 US2002103512 A1 US 2002103512A1
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seizure
predicting
controlling
onset
feature
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US6594524B2 (en
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Javier Echauz
Brian Litt
Rosana Esteller
George Vachtsevanos
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University of Pennsylvania Penn
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University of Pennsylvania Penn
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Assigned to TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE reassignment TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: LITT, BRIAN, ECHAUZ, JAVIER RAMON, ESTELLER, ROSANA, VACHTSEVANOS, GEORGE JOHN
Priority to AU2002245110A priority patent/AU2002245110A1/en
Priority to CA002425122A priority patent/CA2425122A1/en
Priority to PCT/US2001/048035 priority patent/WO2002049500A2/en
Priority to EP01993260A priority patent/EP1341580A4/en
Publication of US20020103512A1 publication Critical patent/US20020103512A1/en
Priority to US10/358,039 priority patent/US7146218B2/en
Publication of US6594524B2 publication Critical patent/US6594524B2/en
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Priority to US11/469,029 priority patent/US8065011B2/en
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    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
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    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/369—Electroencephalography [EEG]
    • A—HUMAN NECESSITIES
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    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
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    • A61B5/48—Other medical applications
    • A61B5/486—Bio-feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
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    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7253—Details of waveform analysis characterised by using transforms
    • A61B5/726—Details of waveform analysis characterised by using transforms using Wavelet transforms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
    • A61B5/7267—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems involving training the classification device
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F2218/00—Aspects of pattern recognition specially adapted for signal processing
    • G06F2218/08—Feature extraction

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  • Primary Health Care (AREA)
  • Computer Vision & Pattern Recognition (AREA)
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  • Child & Adolescent Psychology (AREA)
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  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Electrotherapy Devices (AREA)
US09/735,364 2000-12-12 2000-12-12 Adaptive method and apparatus for forecasting and controlling neurological disturbances under a multi-level control Expired - Lifetime US6594524B2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
US09/735,364 US6594524B2 (en) 2000-12-12 2000-12-12 Adaptive method and apparatus for forecasting and controlling neurological disturbances under a multi-level control
EP01993260A EP1341580A4 (en) 2000-12-12 2001-12-11 ADAPTIVE PROCESS AND DEVICE FOR PREDICTING AND CONTROLLING NEUROLOGICAL INTERFERENCE UNDER MULTILEVEL CONTROL
CA002425122A CA2425122A1 (en) 2000-12-12 2001-12-11 Forecasting and controlling neurological disturbances
PCT/US2001/048035 WO2002049500A2 (en) 2000-12-12 2001-12-11 Forecasting and controlling neurological disturbances
AU2002245110A AU2002245110A1 (en) 2000-12-12 2001-12-11 Forecasting and controlling neurological disturbances
US10/358,039 US7146218B2 (en) 2000-12-12 2003-02-04 Adaptive method and apparatus for forecasting and controlling neurological disturbances under a multi-level control
US11/469,029 US8065011B2 (en) 2000-12-12 2006-08-31 Adaptive method and apparatus for forecasting and controlling neurological disturbances under a multi-level control

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Application Number Priority Date Filing Date Title
US09/735,364 US6594524B2 (en) 2000-12-12 2000-12-12 Adaptive method and apparatus for forecasting and controlling neurological disturbances under a multi-level control

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US10/358,039 Division US7146218B2 (en) 2000-12-12 2003-02-04 Adaptive method and apparatus for forecasting and controlling neurological disturbances under a multi-level control
US10/358,039 Continuation US7146218B2 (en) 2000-12-12 2003-02-04 Adaptive method and apparatus for forecasting and controlling neurological disturbances under a multi-level control

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US10/358,039 Expired - Lifetime US7146218B2 (en) 2000-12-12 2003-02-04 Adaptive method and apparatus for forecasting and controlling neurological disturbances under a multi-level control
US11/469,029 Expired - Lifetime US8065011B2 (en) 2000-12-12 2006-08-31 Adaptive method and apparatus for forecasting and controlling neurological disturbances under a multi-level control

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US11/469,029 Expired - Lifetime US8065011B2 (en) 2000-12-12 2006-08-31 Adaptive method and apparatus for forecasting and controlling neurological disturbances under a multi-level control

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US (3) US6594524B2 (US20020103512A1-20020801-M00022.png)
EP (1) EP1341580A4 (US20020103512A1-20020801-M00022.png)
AU (1) AU2002245110A1 (US20020103512A1-20020801-M00022.png)
CA (1) CA2425122A1 (US20020103512A1-20020801-M00022.png)
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Cited By (121)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100425532B1 (ko) * 2001-04-19 2004-03-30 학교법인 포항공과대학교 위상 패턴의 비선형 주기성을 이용한 간질 발작 예측시스템 및 그 구현 방법
US20040093166A1 (en) * 2002-09-13 2004-05-13 Kil David H. Interactive and automated tissue image analysis with global training database and variable-abstraction processing in cytological specimen classification and laser capture microdissection applications
US20040137639A1 (en) * 2001-04-25 2004-07-15 Wasei Miyazaki Method of judging efficacy of biological state action affecting bioligical state, judging apparatus, judging system, judging program and recording medium holding the program
US20040267152A1 (en) * 2003-02-26 2004-12-30 Pineda Jaime A. Method and system for predicting and preventing seizures
US20050060007A1 (en) * 2003-09-15 2005-03-17 Goetz Steven M. Selection of neurostimulator parameter configurations using decision trees
US20050060009A1 (en) * 2003-09-15 2005-03-17 Goetz Steven M. Selection of neurostimulator parameter configurations using genetic algorithms
US20050060010A1 (en) * 2003-09-15 2005-03-17 Goetz Steven M. Selection of neurostimulator parameter configurations using neural network
US20050060008A1 (en) * 2003-09-15 2005-03-17 Goetz Steven M. Selection of neurostimulator parameter configurations using bayesian networks
US20050107893A1 (en) * 2002-04-12 2005-05-19 Infineon Technologies Ag Event detection - apparatus and method for measuring the activity of neural netwoks
US20050149238A1 (en) * 2004-01-05 2005-07-07 Arinc Inc. System and method for monitoring and reporting aircraft quick access recorder data
WO2005117693A1 (en) * 2004-05-27 2005-12-15 Children's Medical Center Corporation Patient-specific seizure onset detection system
US20060020290A1 (en) * 2004-07-20 2006-01-26 Medtronic, Inc. Medical device with memory upload trigger
EP1624798A2 (en) * 2003-05-06 2006-02-15 George Mason Intellectual Property Phase and state dependent eeg and brain imaging
US7035690B2 (en) 2002-11-15 2006-04-25 Medtronic, Inc. Human-implantable-neurostimulator user interface having multiple levels of abstraction
US20060136806A1 (en) * 2004-12-22 2006-06-22 Pharmacyclics, Inc. System and method for analysis of neurological condition
US20070067050A1 (en) * 2005-09-20 2007-03-22 Honeywell International Inc. Method for soft-computing supervision of dynamical processes with multiple control objectives
US20070150024A1 (en) * 2005-12-28 2007-06-28 Leyde Kent W Methods and systems for recommending an appropriate action to a patient for managing epilepsy and other neurological disorders
US20070203537A1 (en) * 2006-02-24 2007-08-30 Medtronic, Inc. Programming interface with an unwrapped 2D view of a stimulation lead with complex electrode array geometry
US20070203541A1 (en) * 2006-02-24 2007-08-30 Medtronic, Inc Programming interface with a cross-sectional view of a stimulation lead with complex electrode array geometry
US20070203546A1 (en) * 2006-02-24 2007-08-30 Medtronic, Inc. Electrical and activation field models for configuring stimulation therapy
US20070213785A1 (en) * 2006-03-10 2007-09-13 Medtronic, Inc. Probabilistic neurological disorder treatment
US20070213786A1 (en) * 2005-12-19 2007-09-13 Sackellares James C Closed-loop state-dependent seizure prevention systems
US20070225932A1 (en) * 2006-02-02 2007-09-27 Jonathan Halford Methods, systems and computer program products for extracting paroxysmal events from signal data using multitaper blind signal source separation analysis
US20070225674A1 (en) * 2006-03-24 2007-09-27 Medtronic, Inc. Method and Apparatus for the Treatment of Movement Disorders
US20070249953A1 (en) * 2006-04-21 2007-10-25 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US20070249954A1 (en) * 2006-04-21 2007-10-25 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US20070249956A1 (en) * 2006-04-21 2007-10-25 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US20070249955A1 (en) * 2006-04-21 2007-10-25 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US20070250133A1 (en) * 2006-04-21 2007-10-25 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US20070255346A1 (en) * 2006-04-28 2007-11-01 Medtronic, Inc. Tree-based electrical stimulator programming
US20070255321A1 (en) * 2006-04-28 2007-11-01 Medtronic, Inc. Efficacy visualization
WO2007124191A1 (en) * 2006-04-21 2007-11-01 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US20080147130A1 (en) * 2005-02-28 2008-06-19 Rami Rom Adaptive Cardiac Resyncronization Therapy and Vagal Stimulation System
US20080161713A1 (en) * 2006-12-27 2008-07-03 Kent Leyde Low Power Device With Variable Scheduling
US20080183096A1 (en) * 2007-01-25 2008-07-31 David Snyder Systems and Methods for Identifying a Contra-ictal Condition in a Subject
EP1971394A2 (en) * 2005-12-28 2008-09-24 NeuroVista Corporation Methods and systems for recommending an action to a patient for managing epilepsy and other neurological disorders
US7433732B1 (en) 2004-02-25 2008-10-07 University Of Florida Research Foundation, Inc. Real-time brain monitoring system
US20090018466A1 (en) * 2007-06-25 2009-01-15 Tinnitus Otosound Products, Llc System for customized sound therapy for tinnitus management
US20090054800A1 (en) * 2005-07-22 2009-02-26 Centre National De La Recherche Scientifique-Cnrs- Method and Device for Representing A Dynamic Functional Image of the Brain, By Locating and Discriminating Intracerebral Neuroelectric Generators and Uses Thereof
US20090062682A1 (en) * 2007-07-27 2009-03-05 Michael Bland Patient Advisory Device
US20090082829A1 (en) * 2007-09-26 2009-03-26 Medtronic, Inc. Patient directed therapy control
US20090099627A1 (en) * 2007-10-16 2009-04-16 Medtronic, Inc. Therapy control based on a patient movement state
US20090099474A1 (en) * 2007-10-01 2009-04-16 Pineda Jaime A System and method for combined bioelectric sensing and biosensory feedback based adaptive therapy for medical disorders
US20090124926A1 (en) * 2005-12-05 2009-05-14 Masami Funakura Environment control device, environment control method, environment control program, and environment control system
US20090132004A1 (en) * 2004-06-08 2009-05-21 Robert Greenberg Automatic Fitting for a Visual Prosthesis
WO2009091583A1 (en) * 2008-01-16 2009-07-23 Massachusetts Institute Of Technology Method and apparatus for predicting patient outcomes form a physiological segmentable patient signal
US20090264789A1 (en) * 2007-09-26 2009-10-22 Medtronic, Inc. Therapy program selection
US20090276062A1 (en) * 2005-07-11 2009-11-05 Etsuko Kanai Environment control device, environment control method, environment control program, and computer-readable recording medium containing the environment control program
US20100016748A1 (en) * 2008-07-17 2010-01-21 Syed Zeeshan H Motif Discovery in Physiological Datasets: A Methodology for Inferring Predictive Elements
US7676263B2 (en) 2006-06-23 2010-03-09 Neurovista Corporation Minimally invasive system for selecting patient-specific therapy parameters
US7676273B2 (en) 2006-02-24 2010-03-09 Medtronic, Inc. Stimulation templates for programming a stimulation lead with complex electrode array geometry
US20100145402A1 (en) * 2006-07-17 2010-06-10 Rami Rom Intelligent control system for adaptive cardiac resynchronization therapy device
US7747325B2 (en) 1998-08-05 2010-06-29 Neurovista Corporation Systems and methods for monitoring a patient's neurological disease state
US20100180344A1 (en) * 2009-01-10 2010-07-15 Kaspersky Labs ZAO Systems and Methods For Malware Classification
US20100210894A1 (en) * 2006-12-01 2010-08-19 Beth Israel Deaconess Medical Center, Inc. Transcranial magnetic stimulation (TMS) methods and apparatus
US7826902B2 (en) 2006-02-24 2010-11-02 Medtronic, Inc. User interface with 2D views for configuring stimulation therapy
US7848802B2 (en) 2006-02-24 2010-12-07 Medtronic, Inc. Programming interface with a concentric axial view of a stimulation lead with complex electrode array geometry
US7853329B2 (en) 1998-08-05 2010-12-14 Neurovista Corporation Monitoring efficacy of neural modulation therapy
US20110090358A1 (en) * 2009-10-19 2011-04-21 Canon Kabushiki Kaisha Image pickup apparatus, information processing apparatus, and information processing method
US20110218950A1 (en) * 2008-06-02 2011-09-08 New York University Method, system, and computer-accessible medium for classification of at least one ictal state
US8036736B2 (en) 2007-03-21 2011-10-11 Neuro Vista Corporation Implantable systems and methods for identifying a contra-ictal condition in a subject
US20120071779A1 (en) * 2010-09-16 2012-03-22 General Electric Company Method, apparatus and computer program product for automatic seizure monitoring
US8204583B2 (en) 2007-10-23 2012-06-19 Optima Neuroscience, Inc. System for seizure monitoring and detection
WO2012109447A1 (en) * 2011-02-09 2012-08-16 The Charles Stark Draper Laboratory, Inc. Wireless, implantable electro-encephalography system
US8295934B2 (en) 2006-11-14 2012-10-23 Neurovista Corporation Systems and methods of reducing artifact in neurological stimulation systems
US8306624B2 (en) 2006-04-28 2012-11-06 Medtronic, Inc. Patient-individualized efficacy rating
US20130123872A1 (en) * 2011-11-03 2013-05-16 Pacesetter, Inc. Leadless implantable medical device with dual chamber sensing functionality
US8452415B2 (en) 2006-02-24 2013-05-28 Medtronic, Inc. Electrical and activation field models for programming a stimulation lead with complex electrode array geometry
US8543217B2 (en) 2006-02-24 2013-09-24 Medtronic, Inc. Stimulation templates for configuring stimulation therapy
US8588933B2 (en) 2009-01-09 2013-11-19 Cyberonics, Inc. Medical lead termination sleeve for implantable medical devices
US20130331727A1 (en) * 2011-01-28 2013-12-12 Agency For Science, Technology And Research Method and system for detecting attention
US8612024B2 (en) 2006-02-24 2013-12-17 Medtronic, Inc. User interface with 3D environment for configuring stimulation therapy
US8725243B2 (en) 2005-12-28 2014-05-13 Cyberonics, Inc. Methods and systems for recommending an appropriate pharmacological treatment to a patient for managing epilepsy and other neurological disorders
US20140135589A1 (en) * 2012-11-15 2014-05-15 Flint Hills Scientific, L.L.C. Sensor systems implantable at bones of the face or the skull base
US8762065B2 (en) 1998-08-05 2014-06-24 Cyberonics, Inc. Closed-loop feedback-driven neuromodulation
US20140194768A1 (en) * 2011-09-19 2014-07-10 Persyst Development Corporation Method And System To Calculate qEEG
US8786624B2 (en) 2009-06-02 2014-07-22 Cyberonics, Inc. Processing for multi-channel signals
US8849390B2 (en) 2008-12-29 2014-09-30 Cyberonics, Inc. Processing for multi-channel signals
US9042988B2 (en) 1998-08-05 2015-05-26 Cyberonics, Inc. Closed-loop vagus nerve stimulation
US20150297108A1 (en) * 2014-04-22 2015-10-22 Charles J. Chase Cognitive Enhancement Using Feedback
US9259591B2 (en) 2007-12-28 2016-02-16 Cyberonics, Inc. Housing for an implantable medical device
US9279749B2 (en) 2004-09-09 2016-03-08 Life Technologies Corporation Laser microdissection method and apparatus
US9295393B2 (en) 2012-11-09 2016-03-29 Elwha Llc Embolism deflector
US9295397B2 (en) 2013-06-14 2016-03-29 Massachusetts Institute Of Technology Method and apparatus for beat-space frequency domain prediction of cardiovascular death after acute coronary event
US9375573B2 (en) 1998-08-05 2016-06-28 Cyberonics, Inc. Systems and methods for monitoring a patient's neurological disease state
US9415222B2 (en) 1998-08-05 2016-08-16 Cyberonics, Inc. Monitoring an epilepsy disease state with a supervisory module
US9421373B2 (en) 1998-08-05 2016-08-23 Cyberonics, Inc. Apparatus and method for closed-loop intracranial stimulation for optimal control of neurological disease
US9622675B2 (en) 2007-01-25 2017-04-18 Cyberonics, Inc. Communication error alerting in an epilepsy monitoring system
US9643019B2 (en) 2010-02-12 2017-05-09 Cyberonics, Inc. Neurological monitoring and alerts
US9706957B2 (en) 2008-01-25 2017-07-18 Medtronic, Inc. Sleep stage detection
US9770204B2 (en) 2009-11-11 2017-09-26 Medtronic, Inc. Deep brain stimulation for sleep and movement disorders
US20170304625A1 (en) * 2014-10-06 2017-10-26 The Trustees Of Princeton University Adaptive cognitive prosthetic and applications thereof
US20170311870A1 (en) * 2014-11-14 2017-11-02 Neurochip Corporation, C/O Zbx Corporation Method and apparatus for processing electroencephalogram (eeg) signals
US20180189678A1 (en) * 2016-12-29 2018-07-05 Arizona Board of Regents on behalf of Arizona Stat e University Brain-mobile interface optimization using internet-of-things
US10156501B2 (en) 2001-11-05 2018-12-18 Life Technologies Corporation Automated microdissection instrument for determining a location of a laser beam projection on a worksurface area
WO2019173106A1 (en) * 2018-03-09 2019-09-12 Children’S Hospital & Research Center At Oakland Method of detecting and/or predicting seizures
US10463270B2 (en) 2006-12-27 2019-11-05 Livanova Usa, Inc. Low power device with contingent scheduling
US10600305B2 (en) * 2016-04-08 2020-03-24 Vivint, Inc. Event based monitoring of a person
JP2020512860A (ja) * 2017-03-31 2020-04-30 バイオセレニティＢｉｏｓｅｒｅｎｉｔｙ 頭皮脳波から病理学的脳活動を特定する方法
US10653368B1 (en) * 2013-09-09 2020-05-19 Cerner Innovation, Inc. Determining when to emit an alarm
EP3656299A1 (en) * 2018-11-21 2020-05-27 A-Neuron Electronic Corp. Method and sytem for neurological event detection
US10735887B1 (en) * 2019-09-19 2020-08-04 Wave Sciences, LLC Spatial audio array processing system and method
CN112043261A (zh) * 2020-09-29 2020-12-08 黑龙江吉远健康科技有限公司 一种基于肢端动作信号的癫痫发作状态识别方法
US10937548B2 (en) * 2016-10-25 2021-03-02 Wisconsin Alumni Research Foundation Computerized system for efficient augmentation of data sets
CN112774036A (zh) * 2021-02-05 2021-05-11 杭州诺为医疗技术有限公司 植入式闭环系统多通道的电信号处理方法和装置
US20210366602A1 (en) * 2017-12-28 2021-11-25 Nec Corporation Signal-processing device, analysis system, signal-processing method, and signal-processing program
US11185695B1 (en) * 2003-11-26 2021-11-30 Flint Hills Scientific, L.L.C. Method and system for logging quantitative seizure information and assessing efficacy of therapy using cardiac signals
EP3925537A1 (en) * 2020-06-16 2021-12-22 A-Neuron Electronic Corp. Method and system for processing electroencephalogram signal
CN114010207A (zh) * 2022-01-10 2022-02-08 博睿康科技（常州）股份有限公司 基于过零点系数的时域数据分类方法、植入式刺激系统
US11273283B2 (en) 2017-12-31 2022-03-15 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to enhance emotional response
CN114642440A (zh) * 2022-05-23 2022-06-21 博睿康科技（常州）股份有限公司 获取刺激系统预设时长的方法、刺激系统及其调控方法
US11364361B2 (en) 2018-04-20 2022-06-21 Neuroenhancement Lab, LLC System and method for inducing sleep by transplanting mental states
US11406317B2 (en) 2007-12-28 2022-08-09 Livanova Usa, Inc. Method for detecting neurological and clinical manifestations of a seizure
US11452839B2 (en) 2018-09-14 2022-09-27 Neuroenhancement Lab, LLC System and method of improving sleep
US20220338789A1 (en) * 2020-04-05 2022-10-27 Epitel, Inc. Eeg recording and analysis
CN115804572A (zh) * 2023-02-07 2023-03-17 之江实验室 一种癫痫发作自动监护系统及装置
US11717686B2 (en) 2017-12-04 2023-08-08 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to facilitate learning and performance
US11723579B2 (en) 2017-09-19 2023-08-15 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement
US11786694B2 (en) 2019-05-24 2023-10-17 NeuroLight, Inc. Device, method, and app for facilitating sleep
US11857330B1 (en) 2022-10-19 2024-01-02 Epitel, Inc. Systems and methods for electroencephalogram monitoring
US11969249B2 (en) 2021-04-28 2024-04-30 Epitel, Inc. Self-contained EEG recording system

Families Citing this family (255)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7231254B2 (en) * 1998-08-05 2007-06-12 Bioneuronics Corporation Closed-loop feedback-driven neuromodulation
US7974696B1 (en) 1998-08-05 2011-07-05 Dilorenzo Biomedical, Llc Closed-loop autonomic neuromodulation for optimal control of neurological and metabolic disease
JP3151489B2 (ja) * 1998-10-05 2001-04-03 運輸省船舶技術研究所長 音声による疲労・居眠り検知装置及び記録媒体
US6341236B1 (en) * 1999-04-30 2002-01-22 Ivan Osorio Vagal nerve stimulation techniques for treatment of epileptic seizures
US6587719B1 (en) 1999-07-01 2003-07-01 Cyberonics, Inc. Treatment of obesity by bilateral vagus nerve stimulation
US6882881B1 (en) * 1999-10-19 2005-04-19 The Johns Hopkins University Techniques using heat flow management, stimulation, and signal analysis to treat medical disorders
US6738661B1 (en) * 1999-10-22 2004-05-18 Biosynergetics, Inc. Apparatus and methods for the controllable modification of compound concentration in a tube
US6609025B2 (en) 2001-01-02 2003-08-19 Cyberonics, Inc. Treatment of obesity by bilateral sub-diaphragmatic nerve stimulation
US6631291B2 (en) * 2001-05-18 2003-10-07 Instrumentarium Corp. Closed loop drug administration method and apparatus using EEG complexity for control purposes
US6810285B2 (en) 2001-06-28 2004-10-26 Neuropace, Inc. Seizure sensing and detection using an implantable device
NZ530434A (en) * 2001-07-02 2005-01-28 Battelle Memorial Institute Intelligent microsensor module
DE10156556A1 (de) * 2001-11-20 2003-07-17 Ags Medicare Gmbh Einrichtung zur Ermittlung von Schlafprofilen
FR2837302A1 (fr) * 2002-03-13 2003-09-19 Thales Sa Procede de prediction d'evenements de trafic aerien, notamment pour une aide a la decision des compagnies aeriennes et des aeroports
US6735467B2 (en) * 2002-04-15 2004-05-11 Persyst Development Corporation Method and system for detecting seizures using electroencephalograms
US20040199482A1 (en) * 2002-04-15 2004-10-07 Wilson Scott B. Systems and methods for automatic and incremental learning of patient states from biomedical signals
US7299088B1 (en) * 2002-06-02 2007-11-20 Nitish V Thakor Apparatus and methods for brain rhythm analysis
US6934580B1 (en) * 2002-07-20 2005-08-23 Flint Hills Scientific, L.L.C. Stimulation methodologies and apparatus for control of brain states
WO2004031919A2 (en) * 2002-10-03 2004-04-15 Scott Laboratories, Inc. Neural networks in sedation and analgesia systems
US8738136B2 (en) 2002-10-15 2014-05-27 Medtronic, Inc. Clustering of recorded patient neurological activity to determine length of a neurological event
WO2004036376A2 (en) 2002-10-15 2004-04-29 Medtronic Inc. Multi-modal operation of a medical device system
EP1562674A4 (en) * 2002-10-15 2008-10-08 Medtronic Inc CONTROL OF TREATMENT THERAPY DURING STARTING AND DURING OPERATION OF A MEDICAL DEVICE SYSTEM
AU2003291644A1 (en) * 2002-10-15 2004-05-04 Medtronic Inc. Signal quality monitoring and control for a medical device system
WO2004036377A2 (en) * 2002-10-15 2004-04-29 Medtronic Inc. Configuring and testing treatment therapy parameters for a medical device system
AU2003301255A1 (en) * 2002-10-15 2004-05-04 Medtronic Inc. Screening techniques for management of a nervous system disorder
ATE537748T1 (de) * 2002-10-15 2012-01-15 Medtronic Inc Medizinisches vorrichtungssystem zur bewertung von gemessenen neurologischen ereignissen
WO2004034885A2 (en) 2002-10-15 2004-04-29 Medtronic Inc. Signal quality monitoring and control for a medical device system
US7149572B2 (en) 2002-10-15 2006-12-12 Medtronic, Inc. Phase shifting of neurological signals in a medical device system
AU2003294454A1 (en) * 2002-11-22 2004-06-18 International Rehabilitative Sciences, Inc. Surface stimulation for tremor control
CA2429375A1 (en) * 2003-05-22 2004-11-22 Cognos Incorporated Model action logging
EP1696999A4 (en) * 2003-07-21 2008-05-28 Ai Semi Ltd THERAPEUTIC SYSTEM FOR ADAPTIVE RESYNCHRONIZATION
US7596535B2 (en) * 2003-09-29 2009-09-29 Biotronik Gmbh & Co. Kg Apparatus for the classification of physiological events
US20050071304A1 (en) * 2003-09-29 2005-03-31 Biotronik Mess-Und Therapiegeraete Gmbh & Co. Apparatus for the classification of physiological events
US7187967B2 (en) * 2003-09-30 2007-03-06 Neural Signals, Inc. Apparatus and method for detecting neural signals and using neural signals to drive external functions
US20060074449A1 (en) * 2003-11-03 2006-04-06 Stephen Denker Intravascular stimulation system with wireless power supply
US20050143589A1 (en) * 2003-11-09 2005-06-30 Donoghue John P. Calibration systems and methods for neural interface devices
KR100827097B1 (ko) * 2004-04-22 2008-05-02 삼성전자주식회사 음성신호 전처리를 위한 가변 길이의 프레임 결정 방법과이를 이용한 음성신호 전처리 방법 및 장치
US20060058853A1 (en) * 2004-09-13 2006-03-16 Jonathan Bentwich Integrated system and method for treating disease using cognitive-training and brain stimulation and computerized magnetic photo-electric stimulator (cmpes)
US20090099623A1 (en) * 2004-09-13 2009-04-16 Neuronix Ltd. Systems and methods for treatment of medical conditions related to the central nervous system and for enhancing cognitive functions
US20090105521A1 (en) * 2004-09-13 2009-04-23 Jonathan Bentwich Systems and methods for assessing and treating medical conditions related to the central nervous system and for enhancing cognitive functions
EP1788937A4 (en) * 2004-09-16 2009-04-01 Brainscope Co Inc METHOD FOR THE ADAPTIVE, COMPLEX, WAVELET-BASED FILTERING OF EEG SIGNALS
US7486988B2 (en) 2004-12-03 2009-02-03 Searete Llc Method and system for adaptive vision modification
US7656569B2 (en) 2004-12-03 2010-02-02 Searete Llc Vision modification with reflected image
US7931373B2 (en) 2004-12-03 2011-04-26 The Invention Science Fund I, Llc Vision modification with reflected image
US8104892B2 (en) 2004-12-03 2012-01-31 The Invention Science Fund I, Llc Vision modification with reflected image
US8244342B2 (en) 2004-12-03 2012-08-14 The Invention Science Fund I, Llc Method and system for adaptive vision modification
US9155483B2 (en) 2004-12-03 2015-10-13 The Invention Science Fund I, Llc Vision modification with reflected image
US7366571B2 (en) * 2004-12-10 2008-04-29 Cyberonics, Inc. Neurostimulator with activation based on changes in body temperature
US8209009B2 (en) * 2004-12-17 2012-06-26 Medtronic, Inc. System and method for segmenting a cardiac signal based on brain stimulation
US20070239060A1 (en) * 2004-12-17 2007-10-11 Medtronic, Inc. System and method for regulating cardiac triggered therapy to the brain
US8108046B2 (en) 2004-12-17 2012-01-31 Medtronic, Inc. System and method for using cardiac events to trigger therapy for treating nervous system disorders
US8112148B2 (en) * 2004-12-17 2012-02-07 Medtronic, Inc. System and method for monitoring cardiac signal activity in patients with nervous system disorders
ATE527016T1 (de) 2004-12-17 2011-10-15 Medtronic Inc System zur überwachung oder behandlung von erkrankungen des nervensystems
US8485979B2 (en) * 2004-12-17 2013-07-16 Medtronic, Inc. System and method for monitoring or treating nervous system disorders
US8214035B2 (en) * 2004-12-17 2012-07-03 Medtronic, Inc. System and method for utilizing brain state information to modulate cardiac therapy
US8209019B2 (en) 2004-12-17 2012-06-26 Medtronic, Inc. System and method for utilizing brain state information to modulate cardiac therapy
US8108038B2 (en) 2004-12-17 2012-01-31 Medtronic, Inc. System and method for segmenting a cardiac signal based on brain activity
US8112153B2 (en) * 2004-12-17 2012-02-07 Medtronic, Inc. System and method for monitoring or treating nervous system disorders
US8095209B2 (en) * 2005-01-06 2012-01-10 Braingate Co., Llc Biological interface system with gated control signal
US8600521B2 (en) 2005-01-27 2013-12-03 Cyberonics, Inc. Implantable medical device having multiple electrode/sensor capability and stimulation based on sensed intrinsic activity
US20060173493A1 (en) * 2005-01-28 2006-08-03 Cyberonics, Inc. Multi-phasic signal for stimulation by an implantable device
US7561918B2 (en) * 2005-01-28 2009-07-14 Cyberonics, Inc. Autocapture in a neurostimulator
US8565867B2 (en) 2005-01-28 2013-10-22 Cyberonics, Inc. Changeable electrode polarity stimulation by an implantable medical device
US7454245B2 (en) * 2005-01-28 2008-11-18 Cyberonics, Inc. Trained and adaptive response in a neurostimulator
US9314633B2 (en) 2008-01-25 2016-04-19 Cyberonics, Inc. Contingent cardio-protection for epilepsy patients
US8260426B2 (en) 2008-01-25 2012-09-04 Cyberonics, Inc. Method, apparatus and system for bipolar charge utilization during stimulation by an implantable medical device
US7310557B2 (en) * 2005-04-29 2007-12-18 Maschino Steven E Identification of electrodes for nerve stimulation in the treatment of eating disorders
US7899540B2 (en) * 2005-04-29 2011-03-01 Cyberonics, Inc. Noninvasively adjustable gastric band
US7835796B2 (en) * 2005-04-29 2010-11-16 Cyberonics, Inc. Weight loss method and device
US20090118612A1 (en) 2005-05-06 2009-05-07 Sorin Grunwald Apparatus and Method for Vascular Access
US20070016069A1 (en) * 2005-05-06 2007-01-18 Sorin Grunwald Ultrasound sensor
US8335564B2 (en) * 2005-05-27 2012-12-18 Rami Rom Ventricle pacing during atrial fibrillation episodes
US7856273B2 (en) 2005-07-28 2010-12-21 Cyberonics, Inc. Autonomic nerve stimulation to treat a gastrointestinal disorder
US7532935B2 (en) * 2005-07-29 2009-05-12 Cyberonics, Inc. Selective neurostimulation for treating mood disorders
US7499752B2 (en) 2005-07-29 2009-03-03 Cyberonics, Inc. Selective nerve stimulation for the treatment of eating disorders
US20070027499A1 (en) * 2005-07-29 2007-02-01 Cyberonics, Inc. Neurostimulation device for treating mood disorders
US20070027486A1 (en) * 2005-07-29 2007-02-01 Cyberonics, Inc. Medical devices for enhancing intrinsic neural activity
ATE480198T1 (de) 2005-08-02 2010-09-15 Neurotherm Inc Gerät, um zu diagnostizieren und nervenfunktionsstörung zu behandeln
EP1754512A3 (en) * 2005-08-18 2008-03-05 Neurotherm, Inc. Method and apparatus for diagnosing and treating neural dysfunction
US7620455B2 (en) 2005-10-25 2009-11-17 Cyberonics, Inc. Cranial nerve stimulation to treat eating disorders
WO2007051118A2 (en) 2005-10-25 2007-05-03 Nxstage Medical, Inc Safety features for medical devices requiring assistance and supervision
US7957796B2 (en) 2005-10-28 2011-06-07 Cyberonics, Inc. Using physiological sensor data with an implantable medical device
US7555344B2 (en) * 2005-10-28 2009-06-30 Cyberonics, Inc. Selective neurostimulation for treating epilepsy
WO2007094830A1 (en) * 2005-11-10 2007-08-23 In Silico Biosciences, Inc. Method and apparatus for computer modeling the human brain for predicting drug effects
US20070149952A1 (en) * 2005-12-28 2007-06-28 Mike Bland Systems and methods for characterizing a patient's propensity for a neurological event and for communicating with a pharmacological agent dispenser
US7996079B2 (en) 2006-01-24 2011-08-09 Cyberonics, Inc. Input response override for an implantable medical device
US7974697B2 (en) * 2006-01-26 2011-07-05 Cyberonics, Inc. Medical imaging feedback for an implantable medical device
US7657310B2 (en) * 2006-01-26 2010-02-02 Cyberonics, Inc. Treatment of reproductive endocrine disorders by vagus nerve stimulation
US7801601B2 (en) 2006-01-27 2010-09-21 Cyberonics, Inc. Controlling neuromodulation using stimulus modalities
US7787945B2 (en) * 2006-03-08 2010-08-31 Neuropace, Inc. Implantable seizure monitor
US8112247B2 (en) * 2006-03-24 2012-02-07 International Business Machines Corporation Resource adaptive spectrum estimation of streaming data
ES2573323T3 (es) 2006-03-29 2016-06-07 Dignity Health Estímulo eléctrico de microrráfaga de nervios craneales para el tratamiento de afecciones médicas
US7962220B2 (en) 2006-04-28 2011-06-14 Cyberonics, Inc. Compensation reduction in tissue stimulation therapy
US7869885B2 (en) 2006-04-28 2011-01-11 Cyberonics, Inc Threshold optimization for tissue stimulation therapy
US20080027346A1 (en) * 2006-05-22 2008-01-31 The Trustees Of The University Of Pennsylvania Method and device for the recording, localization and stimulation-based mapping of epileptic seizures and brain function utilizing the intracranial and extracranial cerebral vasculature and/or central and/or peripheral nervous system
US20070288405A1 (en) * 2006-06-07 2007-12-13 Motorola, Inc. Problem solving mechanism selection facilitation apparatus and method
WO2007148469A1 (ja) * 2006-06-21 2007-12-27 Panasonic Corporation サービス提供システム
ES2664415T3 (es) 2006-07-05 2018-04-19 Precisis Ag Sistema para el tratamiento de trastornos neurológicos mediante estimulación eléctrica
US8073545B2 (en) * 2006-07-21 2011-12-06 Neuropace, Inc. Treatment and warning of recurring therapy and other events using an implantable device
CN100588271C (zh) * 2006-08-08 2010-02-03 安捷伦科技有限公司 基于分组度量和图像度量两者测量视频质量的系统和方法
US8606740B2 (en) * 2006-09-22 2013-12-10 The Trustees Of The University Of Pennsylvania Classification of subcortical structures
JP5415953B2 (ja) 2006-09-25 2014-02-12 コーニンクレッカ フィリップス エヌ ヴェ 脳活動の携帯式監視装置及び方法
US7869867B2 (en) 2006-10-27 2011-01-11 Cyberonics, Inc. Implantable neurostimulator with refractory stimulation
US8036330B2 (en) * 2006-12-29 2011-10-11 Samsung Electronics Co., Ltd. System and method for frequency synchronization in a wireless non-hierarchical network
US8768447B2 (en) * 2007-01-09 2014-07-01 General Electric Company Processing of physiological signal data in patient monitoring
US8265769B2 (en) * 2007-01-31 2012-09-11 Medtronic, Inc. Chopper-stabilized instrumentation amplifier for wireless telemetry
US7385443B1 (en) * 2007-01-31 2008-06-10 Medtronic, Inc. Chopper-stabilized instrumentation amplifier
US9615744B2 (en) 2007-01-31 2017-04-11 Medtronic, Inc. Chopper-stabilized instrumentation amplifier for impedance measurement
US7391257B1 (en) 2007-01-31 2008-06-24 Medtronic, Inc. Chopper-stabilized instrumentation amplifier for impedance measurement
US20080208074A1 (en) * 2007-02-21 2008-08-28 David Snyder Methods and Systems for Characterizing and Generating a Patient-Specific Seizure Advisory System
US7974701B2 (en) 2007-04-27 2011-07-05 Cyberonics, Inc. Dosing limitation for an implantable medical device
US8000788B2 (en) * 2007-04-27 2011-08-16 Medtronic, Inc. Implantable medical device for treating neurological conditions including ECG sensing
US9788750B2 (en) * 2007-04-30 2017-10-17 Medtronic, Inc. Seizure prediction
US8781595B2 (en) * 2007-04-30 2014-07-15 Medtronic, Inc. Chopper mixer telemetry circuit
US8594779B2 (en) * 2007-04-30 2013-11-26 Medtronic, Inc. Seizure prediction
US7932696B2 (en) * 2007-05-14 2011-04-26 Boston Scientific Neuromodulation Corporation Charger alignment indicator with adjustable threshold
US8131352B2 (en) * 2007-06-20 2012-03-06 Neuropace, Inc. System and method for automatically adjusting detection thresholds in a feedback-controlled neurological event detector
EP2170162B1 (en) 2007-06-26 2017-08-23 Vasonova, Inc. Apparatus for endovascular device guiding and positioning using physiological parameters
US8107695B2 (en) * 2007-06-27 2012-01-31 General Electric Company Methods and systems for assessing patient movement in diagnostic imaging
US8463374B2 (en) * 2007-06-28 2013-06-11 University Of Virginia Patent Foundation Method, system and computer program product for controlling complex rhythmic systems
US7623053B2 (en) * 2007-09-26 2009-11-24 Medtronic, Inc. Implantable medical device with low power delta-sigma analog-to-digital converter
US20090082691A1 (en) * 2007-09-26 2009-03-26 Medtronic, Inc. Frequency selective monitoring of physiological signals
US7714757B2 (en) * 2007-09-26 2010-05-11 Medtronic, Inc. Chopper-stabilized analog-to-digital converter
WO2009043039A1 (en) * 2007-09-28 2009-04-02 Arizona Board Of Regents, Acting For And On Behalf Of Arizona State University Methods for applying brain synchronization to epilepsy and other dynamical disorders
US20090118786A1 (en) * 2007-11-02 2009-05-07 Advanced Bionics Corporation Automated fitting system for deep brain stimulation
US7962313B2 (en) * 2007-12-14 2011-06-14 Palo Alto Research Center Incorporated Method and apparatus for using mobile code for distributed data fusion in networked sensing systems
US7938785B2 (en) * 2007-12-27 2011-05-10 Teledyne Scientific & Imaging, Llc Fusion-based spatio-temporal feature detection for robust classification of instantaneous changes in pupil response as a correlate of cognitive response
US8337404B2 (en) 2010-10-01 2012-12-25 Flint Hills Scientific, Llc Detecting, quantifying, and/or classifying seizures using multimodal data
US8571643B2 (en) 2010-09-16 2013-10-29 Flint Hills Scientific, Llc Detecting or validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex
US8382667B2 (en) 2010-10-01 2013-02-26 Flint Hills Scientific, Llc Detecting, quantifying, and/or classifying seizures using multimodal data
US20090234181A1 (en) * 2008-03-14 2009-09-17 Institute For Music And Neurologic Function Assessment Tool For Storing and Sharing Music Therapy Patient Records
DE102008020070A1 (de) * 2008-04-22 2009-10-29 Biotronik Crm Patent Ag Neurostimulator
US8204603B2 (en) 2008-04-25 2012-06-19 Cyberonics, Inc. Blocking exogenous action potentials by an implantable medical device
US20090287140A1 (en) * 2008-05-16 2009-11-19 Rittman Iii William J Electrical stimulation and infusion introducer assembly
JP5653918B2 (ja) 2008-07-30 2015-01-14 エコーレ ポリテクニーク フェデラーレ デ ローザンヌ （イーピーエフエル） 神経標的の最適化された刺激のための装置および方法
US20110224752A1 (en) * 2008-08-29 2011-09-15 Emory University Microelectrode stimulation for treatment of epilepsy or other neurologic disorder
US8457747B2 (en) 2008-10-20 2013-06-04 Cyberonics, Inc. Neurostimulation with signal duration determined by a cardiac cycle
US8417344B2 (en) 2008-10-24 2013-04-09 Cyberonics, Inc. Dynamic cranial nerve stimulation based on brain state determination from cardiac data
US20100113964A1 (en) * 2008-10-31 2010-05-06 Wahlstrand John D Determining intercardiac impedance
US8478402B2 (en) 2008-10-31 2013-07-02 Medtronic, Inc. Determining intercardiac impedance
EP3563902B1 (en) 2008-11-12 2021-07-14 Ecole Polytechnique Fédérale de Lausanne Microfabricated neurostimulation device
US8322249B2 (en) * 2008-12-18 2012-12-04 Foster-Miller, Inc. Robot arm assembly
US20100191304A1 (en) 2009-01-23 2010-07-29 Scott Timothy L Implantable Medical Device for Providing Chronic Condition Therapy and Acute Condition Therapy Using Vagus Nerve Stimulation
WO2010109448A1 (en) * 2009-03-22 2010-09-30 Ai Medical Semiconductor Ltd. Optimal deep brain stimulation therapy with q learning
US8560073B2 (en) * 2009-03-23 2013-10-15 Flint Hills Scientific, Llc System and apparatus for automated quantitative assessment, optimization and logging of the effects of a therapy
US8239028B2 (en) 2009-04-24 2012-08-07 Cyberonics, Inc. Use of cardiac parameters in methods and systems for treating a chronic medical condition
US8827912B2 (en) 2009-04-24 2014-09-09 Cyberonics, Inc. Methods and systems for detecting epileptic events using NNXX, optionally with nonlinear analysis parameters
CA2764044A1 (en) * 2009-06-02 2010-12-09 Purdue Research Foundation Adaptive real-time seizure prediction system and method
US8708905B2 (en) * 2009-06-12 2014-04-29 General Electric Company Method, device and computer product for EEG monitoring, analysis and display
AU2009348760B2 (en) * 2009-06-26 2013-10-10 T&W Engineering A/S EEG monitoring system and method of monitoring an EEG
US20110015537A1 (en) * 2009-07-15 2011-01-20 General Electric Company Method, apparatus and computer program for monitoring specific cerebral activity
US20120221075A1 (en) * 2009-11-02 2012-08-30 Y.K.L. Brain Tech Ltd. Computerized system or device and method for diagnosis and treatment of human, physical and planetary conditions
TWI398238B (zh) * 2009-11-20 2013-06-11 Tzu Chi University Detection and prediction of brainwave emergencies
CA2782710C (en) 2009-12-01 2019-01-22 Ecole Polytechnique Federale De Lausanne Microfabricated neurostimulation device and methods of making and using the same
EP2512331A4 (en) * 2009-12-16 2015-01-14 Ictalcare As SYSTEM FOR PREDICTING EPILEPTIC INCIDENTS
US8532962B2 (en) 2009-12-23 2013-09-10 Honeywell International Inc. Approach for planning, designing and observing building systems
JP5927176B2 (ja) 2010-04-01 2016-06-01 エコーレ ポリテクニーク フェデラーレ デ ローザンヌ （イーピーエフエル） 神経組織と相互作用するためのデバイス、ならびにそれを作製および使用する方法
US8562536B2 (en) 2010-04-29 2013-10-22 Flint Hills Scientific, Llc Algorithm for detecting a seizure from cardiac data
US8649871B2 (en) 2010-04-29 2014-02-11 Cyberonics, Inc. Validity test adaptive constraint modification for cardiac data used for detection of state changes
US8831732B2 (en) 2010-04-29 2014-09-09 Cyberonics, Inc. Method, apparatus and system for validating and quantifying cardiac beat data quality
US8995678B2 (en) 2010-04-30 2015-03-31 Honeywell International Inc. Tactile-based guidance system
US8990049B2 (en) 2010-05-03 2015-03-24 Honeywell International Inc. Building structure discovery and display from various data artifacts at scene
US8538687B2 (en) 2010-05-04 2013-09-17 Honeywell International Inc. System for guidance and navigation in a building
US9050043B2 (en) * 2010-05-04 2015-06-09 Nellcor Puritan Bennett Ireland Systems and methods for wavelet transform scale-dependent multiple-archetyping
WO2011150220A1 (en) * 2010-05-26 2011-12-01 Flint Hills Scientific, L.L.C. Quantitative multivariate analysis of seizures
US9339195B2 (en) * 2010-05-28 2016-05-17 Research Triangle Institute Apparatus, system, and method for seizure symptom detection
US8679009B2 (en) 2010-06-15 2014-03-25 Flint Hills Scientific, Llc Systems approach to comorbidity assessment
US8641646B2 (en) 2010-07-30 2014-02-04 Cyberonics, Inc. Seizure detection using coordinate data
WO2012050847A2 (en) 2010-09-28 2012-04-19 Masimo Corporation Depth of consciousness monitor including oximeter
US9775545B2 (en) 2010-09-28 2017-10-03 Masimo Corporation Magnetic electrical connector for patient monitors
US8684921B2 (en) 2010-10-01 2014-04-01 Flint Hills Scientific Llc Detecting, assessing and managing epilepsy using a multi-variate, metric-based classification analysis
EP2637568B1 (en) 2010-11-08 2017-04-12 Vasonova, Inc. Endovascular navigation system
US8773946B2 (en) 2010-12-30 2014-07-08 Honeywell International Inc. Portable housings for generation of building maps
ITMI20110013A1 (it) * 2011-01-11 2012-07-12 Newronika Srl Sistema e metodo per la determinazione dell'intensita' soglia per la stimolazione transcranica a corrente diretta.
US9326698B2 (en) * 2011-02-18 2016-05-03 The Trustees Of The University Of Pennsylvania Method for automatic, unsupervised classification of high-frequency oscillations in physiological recordings
US9504390B2 (en) 2011-03-04 2016-11-29 Globalfoundries Inc. Detecting, assessing and managing a risk of death in epilepsy
US8725239B2 (en) 2011-04-25 2014-05-13 Cyberonics, Inc. Identifying seizures using heart rate decrease
US9402550B2 (en) 2011-04-29 2016-08-02 Cybertronics, Inc. Dynamic heart rate threshold for neurological event detection
US10568559B2 (en) 2011-05-13 2020-02-25 Saluda Medical Pty Ltd Method and apparatus for measurement of neural response
CA2835486C (en) 2011-05-13 2022-07-19 Saluda Medical Pty Limited Method and apparatus for measurement of neural response - a
US20140236042A1 (en) 2011-05-13 2014-08-21 Saluda Medical Pty. Ltd. Method and apparatus for measurement of neural response
US9974455B2 (en) 2011-05-13 2018-05-22 Saluda Medical Pty Ltd. Method and apparatus for estimating neural recruitment
US9872990B2 (en) 2011-05-13 2018-01-23 Saluda Medical Pty Limited Method and apparatus for application of a neural stimulus
US9342928B2 (en) 2011-06-29 2016-05-17 Honeywell International Inc. Systems and methods for presenting building information
DK177536B1 (en) 2011-07-19 2013-09-16 Ictalcare As Method for detecting seizures
US9888861B2 (en) * 2011-08-25 2018-02-13 Medtronic, Inc. Method and apparatus for detecting a biomarker in the presence of electrical stimulation
US10631760B2 (en) * 2011-09-02 2020-04-28 Jeffrey Albert Dracup Method for prediction, detection, monitoring, analysis and alerting of seizures and other potentially injurious or life-threatening states
US20140194769A1 (en) * 2011-09-19 2014-07-10 Persyst Development Corporation Multiple Patient EEG Monitoring
US10206591B2 (en) 2011-10-14 2019-02-19 Flint Hills Scientific, Llc Seizure detection methods, apparatus, and systems using an autoregression algorithm
US10595787B2 (en) 2011-10-14 2020-03-24 Flint Hills Scientific, Llc Apparatus and systems for event detection using probabilistic measures
WO2013056099A1 (en) * 2011-10-14 2013-04-18 Flint Hills Scientific, Llc Apparatus and systems for event detection using probabilistic measures
US20130109995A1 (en) * 2011-10-28 2013-05-02 Neil S. Rothman Method of building classifiers for real-time classification of neurological states
US9681836B2 (en) 2012-04-23 2017-06-20 Cyberonics, Inc. Methods, systems and apparatuses for detecting seizure and non-seizure states
US10448839B2 (en) 2012-04-23 2019-10-22 Livanova Usa, Inc. Methods, systems and apparatuses for detecting increased risk of sudden death
JP6185048B2 (ja) 2012-05-07 2017-08-23 バソノバ・インコーポレイテッドＶａｓｏｎｏｖａ， Ｉｎｃ． 上大静脈区域及び大静脈心房接合部の検出のためのシステム及び方法
DK178263B1 (en) * 2012-06-12 2015-10-19 Ictalcare As Method and system of detecting seizures
CN103794006B (zh) * 2012-10-31 2016-12-21 国际商业机器公司 用于处理多个传感器的时序数据的方法和装置
WO2014071445A1 (en) 2012-11-06 2014-05-15 Saluda Medical Pty Ltd Method and system for controlling electrical conditions of tissue
US9355105B2 (en) * 2012-12-19 2016-05-31 International Business Machines Corporation Indexing of large scale patient set
US10055538B2 (en) * 2013-01-05 2018-08-21 Qualcomm Incorporated Processing of skin conductance signals to mitigate noise and detect signal features
US10220211B2 (en) 2013-01-22 2019-03-05 Livanova Usa, Inc. Methods and systems to diagnose depression
JP6612733B2 (ja) * 2013-03-14 2019-11-27 パーシスト ディベロップメント コーポレーション ｑＥＥＧの算出方法
US9439150B2 (en) 2013-03-15 2016-09-06 Medtronic, Inc. Control of spectral agressors in a physiological signal montoring device
US9521979B2 (en) 2013-03-15 2016-12-20 Medtronic, Inc. Control of spectral agressors in a physiological signal monitoring device
WO2014194006A1 (en) 2013-05-28 2014-12-04 The Trustees Of The University Of Pennsylvania Methods, systems, and computer readable media for visualization of resection target during epilepsy surgery and for real time spatiotemporal visualization of neurophysiologic biomarkers
JP6730185B2 (ja) 2013-11-15 2020-07-29 サルーダ・メディカル・ピーティーワイ・リミテッド 脳神経電位のモニタリング
CN105848574B9 (zh) * 2013-11-22 2020-01-21 萨鲁达医疗有限公司 用于检测神经测量值中的神经反应的方法和装置
DK3139999T3 (da) 2014-05-05 2020-06-22 Saluda Medical Pty Ltd Forbedret neutral måling
US11311718B2 (en) 2014-05-16 2022-04-26 Aleva Neurotherapeutics Sa Device for interacting with neurological tissue and methods of making and using the same
EP3476430B1 (en) 2014-05-16 2020-07-01 Aleva Neurotherapeutics SA Device for interacting with neurological tissue
AU2014210579B2 (en) 2014-07-09 2019-10-10 Baylor College Of Medicine Providing information to a user through somatosensory feedback
US10632307B2 (en) 2014-07-25 2020-04-28 Saluda Medical Pty Ltd Neural stimulation dosing
US9474894B2 (en) 2014-08-27 2016-10-25 Aleva Neurotherapeutics Deep brain stimulation lead
US9403011B2 (en) 2014-08-27 2016-08-02 Aleva Neurotherapeutics Leadless neurostimulator
US9924904B2 (en) 2014-09-02 2018-03-27 Medtronic, Inc. Power-efficient chopper amplifier
US10154815B2 (en) 2014-10-07 2018-12-18 Masimo Corporation Modular physiological sensors
WO2016077882A1 (en) 2014-11-17 2016-05-26 Saluda Medical Pty Ltd Method and device for detecting a neural response in neural measurements
EP3229890B1 (en) 2014-12-11 2020-05-27 Saluda Medical Pty Limited Implantable electrode positioning
WO2016090436A1 (en) 2014-12-11 2016-06-16 Saluda Medical Pty Ltd Method and device for feedback control of neural stimulation
AU2016208972B2 (en) 2015-01-19 2021-06-24 Saluda Medical Pty Ltd Method and device for neural implant communication
US10130813B2 (en) 2015-02-10 2018-11-20 Neuropace, Inc. Seizure onset classification and stimulation parameter selection
WO2016132228A2 (en) * 2015-02-16 2016-08-25 Nathan Intrator Systems and methods for brain activity interpretation
WO2016161484A2 (en) 2015-04-09 2016-10-13 Saluda Medical Pty Ltd Electrode to nerve distance estimation
US20160328642A1 (en) * 2015-05-06 2016-11-10 Indiana University Research And Technology Corporation Sensor signal processing using an analog neural network
AU2016269837B2 (en) 2015-05-31 2021-10-21 Closed Loop Medical Pty Ltd Brain neurostimulator electrode fitting
AU2016273415B2 (en) 2015-05-31 2021-07-15 Closed Loop Medical Pty Ltd Monitoring brain neural activity
EP3261533A4 (en) 2015-06-01 2018-10-31 Saluda Medical Pty Ltd Motor fibre neuromodulation
US20170148097A1 (en) * 2015-11-23 2017-05-25 Indiana University Research And Technology Corporation Systems and methods for deriving financial information from emotional content analysis
EP3411111A1 (en) 2016-02-02 2018-12-12 Aleva Neurotherapeutics SA Treatment of autoimmune diseases with deep brain stimulation
US11191966B2 (en) 2016-04-05 2021-12-07 Saluda Medical Pty Ltd Feedback control of neuromodulation
EP3474747A4 (en) 2016-06-24 2020-01-22 Saluda Medical Pty Ltd NERVOUS STIMULATION FOR REDUCED ARTIFACT
US10699538B2 (en) 2016-07-27 2020-06-30 Neosensory, Inc. Method and system for determining and providing sensory experiences
WO2018035067A1 (en) * 2016-08-15 2018-02-22 University Of Southern California Stochastic-switched noise stimulation for identification of input-output brain network dynamics and closed loop control
EP3503963A4 (en) 2016-08-25 2020-04-15 Paradromics, Inc. SYSTEM AND METHOD FOR PROCESSING NEURONAL SIGNALS
WO2018048907A1 (en) 2016-09-06 2018-03-15 Neosensory, Inc. C/O Tmc+260 Method and system for providing adjunct sensory information to a user
WO2018151770A1 (en) 2017-02-16 2018-08-23 Neosensory, Inc. Method and system for transforming language inputs into haptic outputs
US10744058B2 (en) 2017-04-20 2020-08-18 Neosensory, Inc. Method and system for providing information to a user
GB201712892D0 (en) * 2017-08-11 2017-09-27 Bernstein David Alexander Wearable medical sensor
US10596377B2 (en) 2017-11-30 2020-03-24 International Business Machines Corporation Seizure detection, prediction and prevention using neurostimulation technology and deep neural network
US11763170B2 (en) * 2018-02-05 2023-09-19 Sony Group Corporation Method and system for predicting discrete sequences using deep context tree weighting
US10702692B2 (en) 2018-03-02 2020-07-07 Aleva Neurotherapeutics Neurostimulation device
CA3098468A1 (en) 2018-04-27 2019-10-31 Saluda Medical Pty Ltd Neurostimulation of mixed nerves
US11443229B2 (en) 2018-08-31 2022-09-13 Sony Group Corporation Method and system for continual learning in an intelligent artificial agent
US11481578B2 (en) 2019-02-22 2022-10-25 Neuropace, Inc. Systems and methods for labeling large datasets of physiological records based on unsupervised machine learning
US11612750B2 (en) 2019-03-19 2023-03-28 Neuropace, Inc. Methods and systems for optimizing therapy using stimulation mimicking natural seizures
EP3745411A1 (en) 2019-05-27 2020-12-02 Universitat Pompeu Fabra A computer implemented method and computer program products for identifying time-frequency features of physiological events
US11123564B2 (en) * 2019-05-30 2021-09-21 A-Neuron Electronic Corporation Electrical stimulation controlling device and electrical stimulation system
US11467667B2 (en) 2019-09-25 2022-10-11 Neosensory, Inc. System and method for haptic stimulation
US11467668B2 (en) 2019-10-21 2022-10-11 Neosensory, Inc. System and method for representing virtual object information with haptic stimulation
US11923078B2 (en) 2019-11-01 2024-03-05 Terumo Cardiovascular Systems Corporation Semi-autonomous medical systems and methods
US20220344059A1 (en) * 2019-11-27 2022-10-27 University Of Pittsburgh - Of The Commonwealth System Of Higher Education System, Method, and Computer Program Product for Detecting and Responding to Patient Neuromorbidity
US11079854B2 (en) 2020-01-07 2021-08-03 Neosensory, Inc. Method and system for haptic stimulation
WO2021142272A1 (en) * 2020-01-09 2021-07-15 Canon U.S.A., Inc. Enhanced planning and visualization with curved instrument pathway and its curved instrument
US11497675B2 (en) 2020-10-23 2022-11-15 Neosensory, Inc. Method and system for multimodal stimulation
US11862147B2 (en) 2021-08-13 2024-01-02 Neosensory, Inc. Method and system for enhancing the intelligibility of information for a user
TWI801128B (zh) * 2022-02-09 2023-05-01 金寶電子工業股份有限公司 味覺回饋裝置、回饋系統及回饋方法

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3837331A (en) 1972-10-24 1974-09-24 S Ross System and method for controlling the nervous system of a living organism
US3967616A (en) 1972-10-24 1976-07-06 Ross Sidney A Multichannel system for and a multifactorial method of controlling the nervous system of a living organism
US3850161A (en) 1973-04-09 1974-11-26 S Liss Method and apparatus for monitoring and counteracting excess brain electrical energy to prevent epileptic seizures and the like
US3863625A (en) 1973-11-02 1975-02-04 Us Health Epileptic seizure warning system
US3993046A (en) 1974-11-06 1976-11-23 Heriberto Fernandez Seizure suppression device
US4566464A (en) 1981-07-27 1986-01-28 Piccone Vincent A Implantable epilepsy monitor apparatus
US4702254A (en) 1983-09-14 1987-10-27 Jacob Zabara Neurocybernetic prosthesis
US4867164A (en) 1983-09-14 1989-09-19 Jacob Zabara Neurocybernetic prosthesis
US5025807A (en) 1983-09-14 1991-06-25 Jacob Zabara Neurocybernetic prosthesis
US4735204A (en) * 1984-09-17 1988-04-05 Cordis Corporation System for controlling an implanted neural stimulator
US4873981A (en) * 1988-10-14 1989-10-17 Somatics, Inc. Electroconvulsive therapy apparatus and method for automatic monitoring of patient seizures
US4878498A (en) * 1988-10-14 1989-11-07 Somatics, Inc. Electroconvulsive therapy apparatus and method for automatic monitoring of patient seizures
US5304206A (en) 1991-11-18 1994-04-19 Cyberonics, Inc. Activation techniques for implantable medical device
US5311876A (en) 1992-11-18 1994-05-17 The Johns Hopkins University Automatic detection of seizures using electroencephalographic signals
US5995868A (en) 1996-01-23 1999-11-30 University Of Kansas System for the prediction, rapid detection, warning, prevention, or control of changes in activity states in the brain of a subject
US5857978A (en) 1996-03-20 1999-01-12 Lockheed Martin Energy Systems, Inc. Epileptic seizure prediction by non-linear methods
US5743860A (en) 1996-03-20 1998-04-28 Lockheed Martin Energy Systems, Inc. Apparatus and method for epileptic seizure detection using non-linear techniques
US5713923A (en) 1996-05-13 1998-02-03 Medtronic, Inc. Techniques for treating epilepsy by brain stimulation and drug infusion
GB2336211B (en) * 1996-09-26 2001-05-02 Chenna Kesavalu Rajagopal Brain monitor
US6016449A (en) 1997-10-27 2000-01-18 Neuropace, Inc. System for treatment of neurological disorders
US6018682A (en) 1998-04-30 2000-01-25 Medtronic, Inc. Implantable seizure warning system
US5928272A (en) 1998-05-02 1999-07-27 Cyberonics, Inc. Automatic activation of a neurostimulator device using a detection algorithm based on cardiac activity
US6366813B1 (en) * 1998-08-05 2002-04-02 Dilorenzo Daniel J. Apparatus and method for closed-loop intracranical stimulation for optimal control of neurological disease
AU5900299A (en) 1998-08-24 2000-03-14 Emory University Method and apparatus for predicting the onset of seizures based on features derived from signals indicative of brain activity
US6161045A (en) * 1999-06-01 2000-12-12 Neuropace, Inc. Method for determining stimulation parameters for the treatment of epileptic seizures

Cited By (242)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9375573B2 (en) 1998-08-05 2016-06-28 Cyberonics, Inc. Systems and methods for monitoring a patient's neurological disease state
US7930035B2 (en) 1998-08-05 2011-04-19 Neurovista Corporation Providing output indicative of subject's disease state
US8762065B2 (en) 1998-08-05 2014-06-24 Cyberonics, Inc. Closed-loop feedback-driven neuromodulation
US7853329B2 (en) 1998-08-05 2010-12-14 Neurovista Corporation Monitoring efficacy of neural modulation therapy
US9042988B2 (en) 1998-08-05 2015-05-26 Cyberonics, Inc. Closed-loop vagus nerve stimulation
US9415222B2 (en) 1998-08-05 2016-08-16 Cyberonics, Inc. Monitoring an epilepsy disease state with a supervisory module
US7747325B2 (en) 1998-08-05 2010-06-29 Neurovista Corporation Systems and methods for monitoring a patient's neurological disease state
US9113801B2 (en) 1998-08-05 2015-08-25 Cyberonics, Inc. Methods and systems for continuous EEG monitoring
US9320900B2 (en) 1998-08-05 2016-04-26 Cyberonics, Inc. Methods and systems for determining subject-specific parameters for a neuromodulation therapy
US8781597B2 (en) 1998-08-05 2014-07-15 Cyberonics, Inc. Systems for monitoring a patient's neurological disease state
US9421373B2 (en) 1998-08-05 2016-08-23 Cyberonics, Inc. Apparatus and method for closed-loop intracranial stimulation for optimal control of neurological disease
KR100425532B1 (ko) * 2001-04-19 2004-03-30 학교법인 포항공과대학교 위상 패턴의 비선형 주기성을 이용한 간질 발작 예측시스템 및 그 구현 방법
US20040137639A1 (en) * 2001-04-25 2004-07-15 Wasei Miyazaki Method of judging efficacy of biological state action affecting bioligical state, judging apparatus, judging system, judging program and recording medium holding the program
US6954700B2 (en) * 2001-04-25 2005-10-11 Computer Convenience Inc. Efficacy of biological state and action affecting biological state, judging apparatus, judging system, judging program and recording medium holding the program
US10156501B2 (en) 2001-11-05 2018-12-18 Life Technologies Corporation Automated microdissection instrument for determining a location of a laser beam projection on a worksurface area
US7809432B2 (en) * 2002-04-12 2010-10-05 Infineon Technologies Ag Event detection—apparatus and method for measuring the activity of neural networks
US20050107893A1 (en) * 2002-04-12 2005-05-19 Infineon Technologies Ag Event detection - apparatus and method for measuring the activity of neural netwoks
US8346483B2 (en) * 2002-09-13 2013-01-01 Life Technologies Corporation Interactive and automated tissue image analysis with global training database and variable-abstraction processing in cytological specimen classification and laser capture microdissection applications
US20040093166A1 (en) * 2002-09-13 2004-05-13 Kil David H. Interactive and automated tissue image analysis with global training database and variable-abstraction processing in cytological specimen classification and laser capture microdissection applications
US20060155333A1 (en) * 2002-11-15 2006-07-13 Medtronic, Inc. Human-implantable-neurostimulator user interface having multiple levels of abstraction
US9656090B2 (en) 2002-11-15 2017-05-23 Medtronic, Inc. Human-implantable-neurostimulator user interface having multiple levels of abstraction
US10441801B2 (en) 2002-11-15 2019-10-15 Medtronic, Inc. Human-implantable-neurostimulator user interface having multiple levels of abstraction
US8538527B2 (en) 2002-11-15 2013-09-17 Medtronic, Inc. Human-implantable-neurostimulator user interface having multiple levels of abstraction
US7623918B2 (en) 2002-11-15 2009-11-24 Medtronic, Inc. Human-implantable-neurostimulator user interface having multiple levels of abstraction
US7035690B2 (en) 2002-11-15 2006-04-25 Medtronic, Inc. Human-implantable-neurostimulator user interface having multiple levels of abstraction
US20040267152A1 (en) * 2003-02-26 2004-12-30 Pineda Jaime A. Method and system for predicting and preventing seizures
US7269455B2 (en) * 2003-02-26 2007-09-11 Pineda Jaime A Method and system for predicting and preventing seizures
EP1624798A2 (en) * 2003-05-06 2006-02-15 George Mason Intellectual Property Phase and state dependent eeg and brain imaging
EP1624798A4 (en) * 2003-05-06 2007-11-28 George Mason Intellectual Prop PHASE AND STATE-RELATED EEG AND BRAIN PRESENTATION
US7184837B2 (en) 2003-09-15 2007-02-27 Medtronic, Inc. Selection of neurostimulator parameter configurations using bayesian networks
US7853323B2 (en) 2003-09-15 2010-12-14 Medtronic, Inc. Selection of neurostimulator parameter configurations using neural networks
US8233990B2 (en) 2003-09-15 2012-07-31 Medtronic, Inc. Selection of neurostimulator parameter configurations using decision trees
US20100070001A1 (en) * 2003-09-15 2010-03-18 Medtronic, Inc. Selection of neurostimulator parameter configurations using decision trees
US20050060007A1 (en) * 2003-09-15 2005-03-17 Goetz Steven M. Selection of neurostimulator parameter configurations using decision trees
US20050060009A1 (en) * 2003-09-15 2005-03-17 Goetz Steven M. Selection of neurostimulator parameter configurations using genetic algorithms
US7617002B2 (en) 2003-09-15 2009-11-10 Medtronic, Inc. Selection of neurostimulator parameter configurations using decision trees
US7252090B2 (en) 2003-09-15 2007-08-07 Medtronic, Inc. Selection of neurostimulator parameter configurations using neural network
US7239926B2 (en) 2003-09-15 2007-07-03 Medtronic, Inc. Selection of neurostimulator parameter configurations using genetic algorithms
US20050060010A1 (en) * 2003-09-15 2005-03-17 Goetz Steven M. Selection of neurostimulator parameter configurations using neural network
US20050060008A1 (en) * 2003-09-15 2005-03-17 Goetz Steven M. Selection of neurostimulator parameter configurations using bayesian networks
US20070276441A1 (en) * 2003-09-15 2007-11-29 Medtronic, Inc. Selection of neurostimulator parameter configurations using neural networks
US11185695B1 (en) * 2003-11-26 2021-11-30 Flint Hills Scientific, L.L.C. Method and system for logging quantitative seizure information and assessing efficacy of therapy using cardiac signals
US7149612B2 (en) * 2004-01-05 2006-12-12 Arinc Incorporated System and method for monitoring and reporting aircraft quick access recorder data
US20050149238A1 (en) * 2004-01-05 2005-07-07 Arinc Inc. System and method for monitoring and reporting aircraft quick access recorder data
US7433732B1 (en) 2004-02-25 2008-10-07 University Of Florida Research Foundation, Inc. Real-time brain monitoring system
WO2005117693A1 (en) * 2004-05-27 2005-12-15 Children's Medical Center Corporation Patient-specific seizure onset detection system
US20090132004A1 (en) * 2004-06-08 2009-05-21 Robert Greenberg Automatic Fitting for a Visual Prosthesis
US8504162B2 (en) * 2004-06-08 2013-08-06 Second Sight Medical Products, Inc. Automatic fitting for a visual prosthesis
WO2006014759A1 (en) * 2004-07-20 2006-02-09 Medtronic, Inc. Medical device with memory upload trigger
US20060020290A1 (en) * 2004-07-20 2006-01-26 Medtronic, Inc. Medical device with memory upload trigger
US9279749B2 (en) 2004-09-09 2016-03-08 Life Technologies Corporation Laser microdissection method and apparatus
US10605706B2 (en) 2004-09-25 2020-03-31 Life Technologies Corporation Automated microdissection instrument with controlled focusing during movement of a laser beam across a tissue sample
US11703428B2 (en) 2004-09-25 2023-07-18 Life Technologies Corporation Automated microdissection instrument and method for processing a biological sample
US11175203B2 (en) 2004-09-25 2021-11-16 Life Technologies Corporation Automated microdissection instrument using tracking information
US20060136806A1 (en) * 2004-12-22 2006-06-22 Pharmacyclics, Inc. System and method for analysis of neurological condition
US20080147130A1 (en) * 2005-02-28 2008-06-19 Rami Rom Adaptive Cardiac Resyncronization Therapy and Vagal Stimulation System
US7894902B2 (en) * 2005-02-28 2011-02-22 Rami Rom Adaptive cardiac resyncronization therapy and vagal stimulation system
US20090276062A1 (en) * 2005-07-11 2009-11-05 Etsuko Kanai Environment control device, environment control method, environment control program, and computer-readable recording medium containing the environment control program
US8140191B2 (en) * 2005-07-11 2012-03-20 Panasonic Corporation Environment control device, environment control method, environment control program, and computer-readable recording medium containing the environment control program
US20090054800A1 (en) * 2005-07-22 2009-02-26 Centre National De La Recherche Scientifique-Cnrs- Method and Device for Representing A Dynamic Functional Image of the Brain, By Locating and Discriminating Intracerebral Neuroelectric Generators and Uses Thereof
US7769474B2 (en) 2005-09-20 2010-08-03 Honeywell International Inc. Method for soft-computing supervision of dynamical processes with multiple control objectives
US20070067050A1 (en) * 2005-09-20 2007-03-22 Honeywell International Inc. Method for soft-computing supervision of dynamical processes with multiple control objectives
US8162845B2 (en) * 2005-12-05 2012-04-24 Panasonic Corporation Environment control device, environment control method, environment control program, and environment control system
US20090124926A1 (en) * 2005-12-05 2009-05-14 Masami Funakura Environment control device, environment control method, environment control program, and environment control system
US20070213786A1 (en) * 2005-12-19 2007-09-13 Sackellares James C Closed-loop state-dependent seizure prevention systems
US9592004B2 (en) 2005-12-28 2017-03-14 Cyberonics, Inc. Methods and systems for managing epilepsy and other neurological disorders
US8868172B2 (en) * 2005-12-28 2014-10-21 Cyberonics, Inc. Methods and systems for recommending an appropriate action to a patient for managing epilepsy and other neurological disorders
US20070150024A1 (en) * 2005-12-28 2007-06-28 Leyde Kent W Methods and systems for recommending an appropriate action to a patient for managing epilepsy and other neurological disorders
US8725243B2 (en) 2005-12-28 2014-05-13 Cyberonics, Inc. Methods and systems for recommending an appropriate pharmacological treatment to a patient for managing epilepsy and other neurological disorders
US9044188B2 (en) 2005-12-28 2015-06-02 Cyberonics, Inc. Methods and systems for managing epilepsy and other neurological disorders
EP1971394A4 (en) * 2005-12-28 2009-04-01 Neurovista Corp METHOD AND SYSTEMS FOR PROPOSING A TREATMENT FOR A PATIENT TO CHECK EPILEPSIA AND OTHER NEUROLOGICAL DISEASES
EP1971394A2 (en) * 2005-12-28 2008-09-24 NeuroVista Corporation Methods and systems for recommending an action to a patient for managing epilepsy and other neurological disorders
US20070225932A1 (en) * 2006-02-02 2007-09-27 Jonathan Halford Methods, systems and computer program products for extracting paroxysmal events from signal data using multitaper blind signal source separation analysis
US9849295B2 (en) 2006-02-24 2017-12-26 Medtronic, Inc. User interface with 3D environment for configuring stimulation therapy
US10661074B2 (en) 2006-02-24 2020-05-26 Medtronic, Inc. Unwrapped 2D view of a stimulation lead with complex electrode array geometry
US7822483B2 (en) 2006-02-24 2010-10-26 Medtronic, Inc. Electrical and activation field models for configuring stimulation therapy
US11090494B2 (en) 2006-02-24 2021-08-17 Medtronic, Inc. User interface with 3D environment for configuring stimulation therapy
US8452415B2 (en) 2006-02-24 2013-05-28 Medtronic, Inc. Electrical and activation field models for programming a stimulation lead with complex electrode array geometry
US11701513B2 (en) 2006-02-24 2023-07-18 Medtronic, Inc. Unwrapped 2D view of a stimulation lead with complex electrode array geometry
US9061160B2 (en) 2006-02-24 2015-06-23 Medtronic, Inc. User interface with 3D environment for configuring stimulation therapy
US9452295B2 (en) 2006-02-24 2016-09-27 Medtronic, Inc. User interface with 3D environment for configuring stimulation therapy
US20070203537A1 (en) * 2006-02-24 2007-08-30 Medtronic, Inc. Programming interface with an unwrapped 2D view of a stimulation lead with complex electrode array geometry
US8380321B2 (en) 2006-02-24 2013-02-19 Medtronic, Inc. Programming interface with a cross-sectional view of a stimulation lead with complex electrode array geometry
US20070203541A1 (en) * 2006-02-24 2007-08-30 Medtronic, Inc Programming interface with a cross-sectional view of a stimulation lead with complex electrode array geometry
US9199090B2 (en) 2006-02-24 2015-12-01 Medtronic, Inc. Unwrapped 2D view of a stimulation lead with complex electrode array geometry
US7676273B2 (en) 2006-02-24 2010-03-09 Medtronic, Inc. Stimulation templates for programming a stimulation lead with complex electrode array geometry
US20070203546A1 (en) * 2006-02-24 2007-08-30 Medtronic, Inc. Electrical and activation field models for configuring stimulation therapy
US10335588B2 (en) 2006-02-24 2019-07-02 Medtronic, Inc. Unwrapped 2D view of a stimulation lead with complex electrode array geometry
US7657319B2 (en) 2006-02-24 2010-02-02 Medtronic, Inc. Programming interface with an unwrapped 2D view of a stimulation lead with complex electrode array geometry
US7826902B2 (en) 2006-02-24 2010-11-02 Medtronic, Inc. User interface with 2D views for configuring stimulation therapy
US10279166B2 (en) 2006-02-24 2019-05-07 Medtronic, Inc. Unwrapped 2D view of a stimulation lead with complex electrode array geometry
US7848802B2 (en) 2006-02-24 2010-12-07 Medtronic, Inc. Programming interface with a concentric axial view of a stimulation lead with complex electrode array geometry
US8538549B2 (en) 2006-02-24 2013-09-17 Medtronic, Inc. Programming interface for stimulation therapy
US8543217B2 (en) 2006-02-24 2013-09-24 Medtronic, Inc. Stimulation templates for configuring stimulation therapy
US10342970B2 (en) 2006-02-24 2019-07-09 Medtronic, Inc. Unwrapped 2D view of a stimulation lead with complex electrode array geometry
US8612024B2 (en) 2006-02-24 2013-12-17 Medtronic, Inc. User interface with 3D environment for configuring stimulation therapy
US10556103B2 (en) 2006-02-24 2020-02-11 Medtronic, Inc. Unwrapped 2D view of a stimulation lead with complex electrode array geometry
US10286216B2 (en) 2006-02-24 2019-05-14 Medtronic, Inc. User interface with 3D environment for configuring stimulation therapy
US8209018B2 (en) 2006-03-10 2012-06-26 Medtronic, Inc. Probabilistic neurological disorder treatment
US20070244407A1 (en) * 2006-03-10 2007-10-18 Medtronic, Inc. Evoked Response to Stimulation
US20070213785A1 (en) * 2006-03-10 2007-09-13 Medtronic, Inc. Probabilistic neurological disorder treatment
US20070225674A1 (en) * 2006-03-24 2007-09-27 Medtronic, Inc. Method and Apparatus for the Treatment of Movement Disorders
US8190251B2 (en) 2006-03-24 2012-05-29 Medtronic, Inc. Method and apparatus for the treatment of movement disorders
WO2007124194A3 (en) * 2006-04-21 2008-05-29 Medtronic Inc Method and apparatus for detection of nervous system disorders
US8165683B2 (en) 2006-04-21 2012-04-24 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US20070249953A1 (en) * 2006-04-21 2007-10-25 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US20070249954A1 (en) * 2006-04-21 2007-10-25 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US8068903B2 (en) * 2006-04-21 2011-11-29 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US20070249956A1 (en) * 2006-04-21 2007-10-25 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US20070249955A1 (en) * 2006-04-21 2007-10-25 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US7979130B2 (en) 2006-04-21 2011-07-12 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US20070250133A1 (en) * 2006-04-21 2007-10-25 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
WO2007124191A1 (en) * 2006-04-21 2007-11-01 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
WO2007124190A2 (en) 2006-04-21 2007-11-01 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US20070265544A1 (en) * 2006-04-21 2007-11-15 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US20100292753A1 (en) * 2006-04-21 2010-11-18 Medtronic, Inc. Method and Apparatus for Detection of Nervous System Disorders
US20080046024A1 (en) * 2006-04-21 2008-02-21 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
WO2007124190A3 (en) * 2006-04-21 2008-05-08 Medtronic Inc Method and apparatus for detection of nervous system disorders
US7764989B2 (en) 2006-04-21 2010-07-27 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US7761146B2 (en) 2006-04-21 2010-07-20 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US7761145B2 (en) * 2006-04-21 2010-07-20 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US8527039B2 (en) 2006-04-21 2013-09-03 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US20100130881A1 (en) * 2006-04-21 2010-05-27 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US7706889B2 (en) 2006-04-28 2010-04-27 Medtronic, Inc. Tree-based electrical stimulator programming
US20070265664A1 (en) * 2006-04-28 2007-11-15 Medtronic, Inc. Tree-based electrical stimulator programming
US8380300B2 (en) 2006-04-28 2013-02-19 Medtronic, Inc. Efficacy visualization
US8311636B2 (en) 2006-04-28 2012-11-13 Medtronic, Inc. Tree-based electrical stimulator programming
US20070255346A1 (en) * 2006-04-28 2007-11-01 Medtronic, Inc. Tree-based electrical stimulator programming
US8306624B2 (en) 2006-04-28 2012-11-06 Medtronic, Inc. Patient-individualized efficacy rating
US20070255321A1 (en) * 2006-04-28 2007-11-01 Medtronic, Inc. Efficacy visualization
US7801619B2 (en) 2006-04-28 2010-09-21 Medtronic, Inc. Tree-based electrical stimulator programming for pain therapy
US7715920B2 (en) 2006-04-28 2010-05-11 Medtronic, Inc. Tree-based electrical stimulator programming
US20070265681A1 (en) * 2006-04-28 2007-11-15 Medtronic, Inc. Tree-based electrical stimulator programming for pain therapy
US7676263B2 (en) 2006-06-23 2010-03-09 Neurovista Corporation Minimally invasive system for selecting patient-specific therapy parameters
US9480845B2 (en) 2006-06-23 2016-11-01 Cyberonics, Inc. Nerve stimulation device with a wearable loop antenna
US8301250B2 (en) * 2006-07-17 2012-10-30 Rami Rom Intelligent control system for adaptive cardiac resynchronization therapy device
US20100145402A1 (en) * 2006-07-17 2010-06-10 Rami Rom Intelligent control system for adaptive cardiac resynchronization therapy device
US8295934B2 (en) 2006-11-14 2012-10-23 Neurovista Corporation Systems and methods of reducing artifact in neurological stimulation systems
US8855775B2 (en) 2006-11-14 2014-10-07 Cyberonics, Inc. Systems and methods of reducing artifact in neurological stimulation systems
US20100210894A1 (en) * 2006-12-01 2010-08-19 Beth Israel Deaconess Medical Center, Inc. Transcranial magnetic stimulation (TMS) methods and apparatus
US9849300B2 (en) * 2006-12-01 2017-12-26 Children's Medical Center Corporation Transcranial magnetic stimulation (TMS) methods and apparatus
US20130338424A1 (en) * 2006-12-01 2013-12-19 Children's Medical Center Corporation Transcranial magnetic stimulation (tms) methods and apparatus
US20080161713A1 (en) * 2006-12-27 2008-07-03 Kent Leyde Low Power Device With Variable Scheduling
US9913593B2 (en) * 2006-12-27 2018-03-13 Cyberonics, Inc. Low power device with variable scheduling
US10463270B2 (en) 2006-12-27 2019-11-05 Livanova Usa, Inc. Low power device with contingent scheduling
US11529089B2 (en) 2006-12-27 2022-12-20 LivaNovaUSA, Inc. Low power device with contingent scheduling
US9622675B2 (en) 2007-01-25 2017-04-18 Cyberonics, Inc. Communication error alerting in an epilepsy monitoring system
US9898656B2 (en) * 2007-01-25 2018-02-20 Cyberonics, Inc. Systems and methods for identifying a contra-ictal condition in a subject
US20080183096A1 (en) * 2007-01-25 2008-07-31 David Snyder Systems and Methods for Identifying a Contra-ictal Condition in a Subject
US8543199B2 (en) 2007-03-21 2013-09-24 Cyberonics, Inc. Implantable systems and methods for identifying a contra-ictal condition in a subject
US9445730B2 (en) 2007-03-21 2016-09-20 Cyberonics, Inc. Implantable systems and methods for identifying a contra-ictal condition in a subject
US8036736B2 (en) 2007-03-21 2011-10-11 Neuro Vista Corporation Implantable systems and methods for identifying a contra-ictal condition in a subject
US20090018466A1 (en) * 2007-06-25 2009-01-15 Tinnitus Otosound Products, Llc System for customized sound therapy for tinnitus management
US9788744B2 (en) * 2007-07-27 2017-10-17 Cyberonics, Inc. Systems for monitoring brain activity and patient advisory device
US20090062682A1 (en) * 2007-07-27 2009-03-05 Michael Bland Patient Advisory Device
US8380314B2 (en) 2007-09-26 2013-02-19 Medtronic, Inc. Patient directed therapy control
US20090082829A1 (en) * 2007-09-26 2009-03-26 Medtronic, Inc. Patient directed therapy control
US20090264789A1 (en) * 2007-09-26 2009-10-22 Medtronic, Inc. Therapy program selection
US9248288B2 (en) 2007-09-26 2016-02-02 Medtronic, Inc. Patient directed therapy control
US10258798B2 (en) 2007-09-26 2019-04-16 Medtronic, Inc. Patient directed therapy control
US20090099474A1 (en) * 2007-10-01 2009-04-16 Pineda Jaime A System and method for combined bioelectric sensing and biosensory feedback based adaptive therapy for medical disorders
US8121694B2 (en) 2007-10-16 2012-02-21 Medtronic, Inc. Therapy control based on a patient movement state
US20090099627A1 (en) * 2007-10-16 2009-04-16 Medtronic, Inc. Therapy control based on a patient movement state
US8554325B2 (en) 2007-10-16 2013-10-08 Medtronic, Inc. Therapy control based on a patient movement state
US8204583B2 (en) 2007-10-23 2012-06-19 Optima Neuroscience, Inc. System for seizure monitoring and detection
US11406317B2 (en) 2007-12-28 2022-08-09 Livanova Usa, Inc. Method for detecting neurological and clinical manifestations of a seizure
US9259591B2 (en) 2007-12-28 2016-02-16 Cyberonics, Inc. Housing for an implantable medical device
US8868163B2 (en) 2008-01-16 2014-10-21 Massachusetts Institute Of Technology Method and apparatus for predicting patient outcomes from a physiological segmentable patient signal
US8346349B2 (en) 2008-01-16 2013-01-01 Massachusetts Institute Of Technology Method and apparatus for predicting patient outcomes from a physiological segmentable patient signal
WO2009091583A1 (en) * 2008-01-16 2009-07-23 Massachusetts Institute Of Technology Method and apparatus for predicting patient outcomes form a physiological segmentable patient signal
US20090192394A1 (en) * 2008-01-16 2009-07-30 Guttag John V Method and apparatus for predicting patient outcomes from a physiological segmentable patient signal
US10165977B2 (en) 2008-01-25 2019-01-01 Medtronic, Inc. Sleep stage detection
US9706957B2 (en) 2008-01-25 2017-07-18 Medtronic, Inc. Sleep stage detection
US20110218950A1 (en) * 2008-06-02 2011-09-08 New York University Method, system, and computer-accessible medium for classification of at least one ictal state
US9443141B2 (en) * 2008-06-02 2016-09-13 New York University Method, system, and computer-accessible medium for classification of at least one ICTAL state
US20100016748A1 (en) * 2008-07-17 2010-01-21 Syed Zeeshan H Motif Discovery in Physiological Datasets: A Methodology for Inferring Predictive Elements
US8340746B2 (en) 2008-07-17 2012-12-25 Massachusetts Institute Of Technology Motif discovery in physiological datasets: a methodology for inferring predictive elements
US8849390B2 (en) 2008-12-29 2014-09-30 Cyberonics, Inc. Processing for multi-channel signals
US8588933B2 (en) 2009-01-09 2013-11-19 Cyberonics, Inc. Medical lead termination sleeve for implantable medical devices
US9289595B2 (en) 2009-01-09 2016-03-22 Cyberonics, Inc. Medical lead termination sleeve for implantable medical devices
US20100180344A1 (en) * 2009-01-10 2010-07-15 Kaspersky Labs ZAO Systems and Methods For Malware Classification
US8786624B2 (en) 2009-06-02 2014-07-22 Cyberonics, Inc. Processing for multi-channel signals
US20110090358A1 (en) * 2009-10-19 2011-04-21 Canon Kabushiki Kaisha Image pickup apparatus, information processing apparatus, and information processing method
US9237266B2 (en) * 2009-10-19 2016-01-12 Canon Kabushiki Kaisha Image pickup apparatus and method for detecting an entrance or exit event of an object in a frame image and medium storing a program causing a computer to function as the apparatus
US9679202B2 (en) 2009-10-19 2017-06-13 Canon Kabushiki Kaisha Information processing apparatus with display control unit configured to display on a display apparatus a frame image, and corresponding information processing method, and medium
US9770204B2 (en) 2009-11-11 2017-09-26 Medtronic, Inc. Deep brain stimulation for sleep and movement disorders
US9643019B2 (en) 2010-02-12 2017-05-09 Cyberonics, Inc. Neurological monitoring and alerts
US20120071779A1 (en) * 2010-09-16 2012-03-22 General Electric Company Method, apparatus and computer program product for automatic seizure monitoring
US9072482B2 (en) * 2010-09-16 2015-07-07 General Electric Company Method and apparatus for automatic seizure monitoring
US20130331727A1 (en) * 2011-01-28 2013-12-12 Agency For Science, Technology And Research Method and system for detecting attention
WO2012109447A1 (en) * 2011-02-09 2012-08-16 The Charles Stark Draper Laboratory, Inc. Wireless, implantable electro-encephalography system
US9326720B2 (en) 2011-02-09 2016-05-03 The Charles Stark Draper Laboratory, Inc. Wireless, implantable electro-encephalography system
US20170188865A1 (en) * 2011-09-19 2017-07-06 Persyst Development Corporation Method And System To Calculate qEEG
US20140194768A1 (en) * 2011-09-19 2014-07-10 Persyst Development Corporation Method And System To Calculate qEEG
US20130123872A1 (en) * 2011-11-03 2013-05-16 Pacesetter, Inc. Leadless implantable medical device with dual chamber sensing functionality
US9414752B2 (en) 2012-11-09 2016-08-16 Elwha Llc Embolism deflector
US9295393B2 (en) 2012-11-09 2016-03-29 Elwha Llc Embolism deflector
US20140135589A1 (en) * 2012-11-15 2014-05-15 Flint Hills Scientific, L.L.C. Sensor systems implantable at bones of the face or the skull base
US9295397B2 (en) 2013-06-14 2016-03-29 Massachusetts Institute Of Technology Method and apparatus for beat-space frequency domain prediction of cardiovascular death after acute coronary event
US10653368B1 (en) * 2013-09-09 2020-05-19 Cerner Innovation, Inc. Determining when to emit an alarm
US11051768B1 (en) 2013-09-09 2021-07-06 Cerner Innovation, Inc. Determining when to emit an alarm
US20150297108A1 (en) * 2014-04-22 2015-10-22 Charles J. Chase Cognitive Enhancement Using Feedback
US9943698B2 (en) * 2014-04-22 2018-04-17 Lockheed Martin Corporation Cognitive enhancement using feedback
US20170304625A1 (en) * 2014-10-06 2017-10-26 The Trustees Of Princeton University Adaptive cognitive prosthetic and applications thereof
EP3203904B1 (en) * 2014-10-06 2020-08-26 The Trustees of Princeton University Adaptive cognitive prosthetic and applications thereof
US10994141B2 (en) * 2014-10-06 2021-05-04 The Trustees Of Princeton University Adaptive cognitive prosthetic and applications thereof
US20170311870A1 (en) * 2014-11-14 2017-11-02 Neurochip Corporation, C/O Zbx Corporation Method and apparatus for processing electroencephalogram (eeg) signals
US10600305B2 (en) * 2016-04-08 2020-03-24 Vivint, Inc. Event based monitoring of a person
US11562637B1 (en) 2016-04-08 2023-01-24 Vivint, Inc. Event based monitoring of a person
US10937548B2 (en) * 2016-10-25 2021-03-02 Wisconsin Alumni Research Foundation Computerized system for efficient augmentation of data sets
US10796246B2 (en) * 2016-12-29 2020-10-06 Arizona Board Of Regents On Behalf Of Arizona State University Brain-mobile interface optimization using internet-of-things
US20180189678A1 (en) * 2016-12-29 2018-07-05 Arizona Board of Regents on behalf of Arizona Stat e University Brain-mobile interface optimization using internet-of-things
US11684303B2 (en) 2017-03-31 2023-06-27 Bioserenity Method for identification of pathological brain activity from scalp electroencephalogram
JP2020512860A (ja) * 2017-03-31 2020-04-30 バイオセレニティＢｉｏｓｅｒｅｎｉｔｙ 頭皮脳波から病理学的脳活動を特定する方法
US11723579B2 (en) 2017-09-19 2023-08-15 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement
US11717686B2 (en) 2017-12-04 2023-08-08 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to facilitate learning and performance
US20210366602A1 (en) * 2017-12-28 2021-11-25 Nec Corporation Signal-processing device, analysis system, signal-processing method, and signal-processing program
US11273283B2 (en) 2017-12-31 2022-03-15 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to enhance emotional response
US11318277B2 (en) 2017-12-31 2022-05-03 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to enhance emotional response
US11478603B2 (en) 2017-12-31 2022-10-25 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to enhance emotional response
WO2019173106A1 (en) * 2018-03-09 2019-09-12 Children’S Hospital & Research Center At Oakland Method of detecting and/or predicting seizures
US11364361B2 (en) 2018-04-20 2022-06-21 Neuroenhancement Lab, LLC System and method for inducing sleep by transplanting mental states
US11452839B2 (en) 2018-09-14 2022-09-27 Neuroenhancement Lab, LLC System and method of improving sleep
EP3656299A1 (en) * 2018-11-21 2020-05-27 A-Neuron Electronic Corp. Method and sytem for neurological event detection
CN111202515A (zh) * 2018-11-21 2020-05-29 晶神医创股份有限公司 神经事件检测方法与系统
US11786694B2 (en) 2019-05-24 2023-10-17 NeuroLight, Inc. Device, method, and app for facilitating sleep
US10735887B1 (en) * 2019-09-19 2020-08-04 Wave Sciences, LLC Spatial audio array processing system and method
US20220338789A1 (en) * 2020-04-05 2022-10-27 Epitel, Inc. Eeg recording and analysis
US11786167B2 (en) * 2020-04-05 2023-10-17 Epitel, Inc. EEG recording and analysis
US11638551B2 (en) 2020-04-05 2023-05-02 Epitel, Inc. EEG recording and analysis
US11779262B2 (en) 2020-04-05 2023-10-10 Epitel, Inc. EEG recording and analysis
EP3925537A1 (en) * 2020-06-16 2021-12-22 A-Neuron Electronic Corp. Method and system for processing electroencephalogram signal
US11602299B2 (en) * 2020-06-16 2023-03-14 A-Neuron Electronic Corporation Method and system for processing electroencephalogram signal
CN112043261A (zh) * 2020-09-29 2020-12-08 黑龙江吉远健康科技有限公司 一种基于肢端动作信号的癫痫发作状态识别方法
CN112774036A (zh) * 2021-02-05 2021-05-11 杭州诺为医疗技术有限公司 植入式闭环系统多通道的电信号处理方法和装置
US11969249B2 (en) 2021-04-28 2024-04-30 Epitel, Inc. Self-contained EEG recording system
WO2023130600A1 (zh) * 2022-01-10 2023-07-13 博睿康科技（常州）股份有限公司 基于过零点系数的时域数据分类方法、植入式刺激系统
CN114010207A (zh) * 2022-01-10 2022-02-08 博睿康科技（常州）股份有限公司 基于过零点系数的时域数据分类方法、植入式刺激系统
CN114642440A (zh) * 2022-05-23 2022-06-21 博睿康科技（常州）股份有限公司 获取刺激系统预设时长的方法、刺激系统及其调控方法
US11857330B1 (en) 2022-10-19 2024-01-02 Epitel, Inc. Systems and methods for electroencephalogram monitoring
US11918368B1 (en) 2022-10-19 2024-03-05 Epitel, Inc. Systems and methods for electroencephalogram monitoring
CN115804572A (zh) * 2023-02-07 2023-03-17 之江实验室 一种癫痫发作自动监护系统及装置

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