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US1934046A - Syringe for hypodermic medical injections - Google Patents

Syringe for hypodermic medical injections Download PDF

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Publication number
US1934046A
US1934046A US60091532A US1934046A US 1934046 A US1934046 A US 1934046A US 60091532 A US60091532 A US 60091532A US 1934046 A US1934046 A US 1934046A
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Prior art keywords
syringe
needle
chamber
bell
portion
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Expired - Lifetime
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Demarchi Mario
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Demarchi Mario
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/425Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means

Description

Nov. 7, 1,933. M. DEMARCHI I SYRINGE FOR HYPODERMIC MEDIQAL INJECTIONS Filed March 24, 1932 INVENTOR WWW AiTQENEY Patented Nov. 7, 1933 UNITED STATES armor: ron monsamc name-nous amnion.

Mario Demarchi, Biella, Italy Application March 24, 1932, Serial No. 600,915, I and in Italy October so, 1931 9 Claims- (Cl. 128-215) This invention relates to syringes, the so-calied Pravatz syringes, for hypodermic or endomuscular injections of medical media, and has for its object to provide an automatic device (which will be called hereinafter, for the sake of brevity, the automatic syringe) which will automatically perform the insertion of the needle in, or the withdrawal thereof from the skin of the patient.

It is known that medical injections have ac- 10 quired for some time a very large diffusion, and that there are patients who continuallymake use of said injections, that is every day or even many times a day; here are to be particularly cited the diabetics for the continuous use made by them of the injections of insulin. In order to allow the syringe of Pravatz to be used by the patient himself, and to render its use easy and safe, several types of automatic syringes have been proposed. These syringes generally comprise a spring device, operated in diilerent ways and comprising different details, by which the automatic and instantaneous insertion of the needle into the skin, and in some typesalso the withdrawal therefrom, are obtained.

as In .all the types heretofore in use, however,

- somedrawback's are to be remarked, such as the disagreeable impression produced in the patient by the noisy trip of the spring, the rough operation of the device-which, in the caseof an an obstacle being met can involve the breaking of l the needle-and, in types in which the withdrawal of the needle is made by hand, the possibility of this operation being made in a slanting direction, thus causing a creeping wound to be galuced by the point of the needle under the The automatic syringe according to this invention avoids the above-mentioned drawbacks, the operation .of same being absolutely noiseless and so being performed, although very rapidly, without,

any rough trip; the operation of this syringe is very nearto that of a syringe used by hand.

when the operation is quickly performed by a skilled person. By this syringe both the insertion 4s and the withdrawal of the needle are automatitally obtained.

According to this invention, the. insertion of the needle into the skin and the tissues which lie beneath, as well as the withdrawal therefrom,

so are obtained by making use of the atmospheric pressure, the pressure existing in a small cuplike or bell-shaped chamber whichis applied 10-.

cally to the skin of the patient,ln the point where the inJection will take place, being caused to vary as for this purpose.

The automatic syringe is provided with a small' chamber, or bell, of glass or other suitable material, the opening of which is applied to the skin; at the top of the bell is fitted the body of the syringe proper, the end thereof which carries .6

the needle being contained in the bell and the needle being directed against the skin, its point, in the initial position, being at a small distance therefrom. The syringe proper can be fitted to the top of the bell in different ways, as it can be as positively fixed there or be mounted there by means which allow it a free movement, between given limits, in the axial direction; in any case the fitting must be air-tight. A suitable means,

such as a common rubber bulb, having a strong m enough structure, allows of the air contained in the bell being sucked out therefrom, so as to produce therein, at the required instant (when the apparatus is being applied to the skin the bell is closed) a considerable vacuum. Owing to the atmospheric pressure, a suction of the tissues of the patient into the bells mouth is then produced, the tissues assuming a convex form.

- while on the other hand, if the syringe is given a free movement, a forward stroke of the syringe at; proper towards the interior of the bell, that is towardsthe skin, takes place.

If the syringe is steadily fixed to the bell, as the said syringe is stationary, the insertion of the needle is caused by the forwarding against it of the tissues of the patient, the first of the above mentioned effects being so only utilized; when on the contrary the syringe is given a free movement, the eflect of this movement is added to the above-mentioned eflect, a deeper insertion of go the needle into the tissues (endomuscular injections) being thus obtained. In both cases it should be noticed that the temporary swelling of the tissue is of assistance-to the insertion of the needle. According to experience the opera- 95 tion causes no. disturbance to the patient,-as it is painless and substantially not perceived by him.

' Three embodiments of the automatic syringe according to this invention are hereinafter described by way of example, with reference to the mo accompanying drawing. in which Figs-1, 2 and 3 illustrate each a suitable form, in lateral view, partially in section.

Referring first to Fig. 1, 1 is the syringe prpper, m5 2istheneedle,$isthebell,of glass,inthei5orm of a reversed funnel, provided with a lateral connection pipe 35 which is fitted with a rubber bulb 5. The bell has at'its top a neck-like aperture 31 in which the syringe l is secured, being In operation, after having manually compressedthe rubber bulb 5, the bells mouth 34 is applied on the skin, on the point where it is required. to execute the injection (the skin heying naturally been previously cleansed and disin- Iected and the syringe .filled with the medical medium) the bulb is then released, and spreading out instantly, on account of its own elasticity, it will cause a suction of air in the bell 3 and then a vacuum therein. As a consequence of the ex ternal atmospheric pressure a suction of the tissue of the patient, in the form of a calotte projecting in the bell, will then take place, and thus the insertion of the needle into the skin. After the injection proper has been performed, it will Bufice to compress again the bulb to obtain the return of the tissue to its initial position, the needle being thus withdrawn. The insertion as well as the withdrawal of the needle take place in a direction perfectly perpendicular to the surface of the skin, the rest of the bell thereon serving to determine in the most certain way the normal position of use of the syringe.

Referring now to Fig. 2, there is illustrated a form of automatic syringe wherein the syringe proper is given a certain possibilityof axial movement, in order to allow deeper injections to be performed. The bell 3 which in this case has been shown in the form or a spherical calotte, provided with the rubber bulb 5 already described mounted on the connection pipe 35, has at the top a neck 31 through whichpasses with a suitable play the syringe 1 and which extends above in the form or a funnel 32 limited by a cylindrical seat 33 to which a thick disc 4' of a soft and elastic material, such as spongy rubber or the like, is fixed by its edge; the disc has a hole 11 at the centre through which passes in an air-tight manner the cylinder of the syringe. Under normal conditions, the disc 4' keeps the syringe in the position shown, wherein the point oi. the needle 2 is at a certain distance from the plane of the mouth 34.;when, however, the atmospheric pressure acts from the exterior upon the disc and the syringe, bemg no longer balanced by an equal pressure in the interior of the bell, the disc 4 bends down as indicated by dotted lines and the syringe assumes the position also indicated by dotted lines. The funnel-like form or the upper extension 32 of the bell assists the piling therein or the elastic material or the disc and so the constitution oi. an efllcient support for thessyringe at the end of its stroke.

The operation oi the syringe is obvious. As soon as the rubber bulb 5 spreads out, thus producing a considerable vacuum in the bell, the syringe is forced forward by the atmospheric pressure against the skin, causing the needle to penetrate therein, whilst the simultaneous suctlon or the tissue into the bell takes place, both eflects thus co-operating to produce a greater depth of penetration.

Referring to Fig. 3, there is illustrated a modifled form which is substantially equivalent to the preceding one so far as the structure and operation are concerned. The same parts already cited in connection with Fig. 2 are to be found here and are indicated by the same reference numbers (the rubber bulb has been omitfed); a diflerence to be noticed is the form oi. the neck 31 which extends internally or the bell 3 for a length 31a while at its top the said neck spreads into a container 32 having sublined there by an air-tight joint such as by means of an apertured rubber plug 4.

stantially the form of a double cone, provided with a wide upper aperture 36. The neck 31. together with its projecting portion 31a. effectively serves to limit, to -a suitable extent, the lateral play of the cylinder of the syringe l. The disc 4' of spongy rubber, or the like, can be of less thickness than in the preceding case, and does not require to be fixed to the seat by its edge, being cut with a diameter considerably v apparatus, the needle will be effectively protected against casual contact with foreign objects, especially after having been sterilized before use. The syringe can also, if required, be kept resting with its hell on a suitable container or on a table on which a small glass [is placed, so that the needle be continually immersed in an antiseptic solution, thus being ready for immediate use even a considerable time after its sterilization.

Obviously various modifications can be introduced in the construction of the embodiments described without departing from the scope of the invention. The form of the bell can particularly be varied in every way, and the connection between the top of same and the syringe proper,

the positive connection as well as the flexible one, can be obtained in many different ways as will be easily conceived bythose skilled in the art. The means used for the suction of the air can also be different.

I claim:

1. The combination, with a hypodermic syringe and its needle, of an attached open mouthed suction chamber, the needle being disposed within the chamber with the point directed towards the mouth, and means for varying the air pressure in said chamber, so that the tissue or a .member, over which the chamber may beposltioned to cause the mouth to be closed by the member, may be automatically pierced by the needle as a result oi relative movement which may be eflected between the needle and the tissue by reducing the air pressure in the chamber.

2. The combination defined by claim 1, of which the suction chamber comprises a neck-like portion into'which extends the end of the syringe which carries the needle, a bell-like portion flaring downwardly and outwardly to the mouth of the chamber, and air sealing means closing the joint between the syringe and a surrounding part 01 the chamber wall above the bell-like portion.

3. The combination defined by claim 1, of which the means for varying the air pressure comprises a resilient bulb and a conduit connecting the bulb with the chamber.

4. The combination defined by claim 1, of which the suction chamber has a neck-like portion of reduced diameter between its mouth and its opposite end into and through which the end of the syringe which carries the needle may be moved, an upwardly and outwardly flaring portionabove the neck-like portion, and an air seal comprising a resilient diaphragm closing the space between the syringe and the surrounding wall of the suction chamber at a level above the neck-like portion, the syringe being held. in a definite position with respect to the surrounding portion of the diaphragm and limited in its downward movement, when air pressure in the chamber is reduced, by engagement of the dia phragm with the underlying flared wall of the chamber.

5. The combination defined by claim 1, in which the syringe is carried by a diaphragm of resilient material which forms a flexible portion of the walls of the chamber, the said diaphragm being conical in form and having an inherent tendency to carry the syringe to its lowermost position when the center of said diaphragm is forced below the plane of its outer edge.

6. The combination defined by claim 1, of which the suction chamber has a neck-like por tion of reduced diameter between its mouth and its opposite end into and through which the end of the syringe which carries the needle may be moved, a portion extended above the neck-like portion flaring upwardly and outwardly and then upwardly and inwardly to form a diaphragm chamber and a diaphragm to sealthe space hetween the syringe and the surrounding wail oi the diaphragm chamber, the diaphragm cornprising a disk of resilient material of such di mensions as compared with those 0: the dia= phragm chamber as to be compressed and distorted into a conical form, the syringe being rnov able with the central part of the diaphragm and normally held thereby in its uppermost position, the diaphragm serving as a means for rapidly moving the syringe to its lowermost position after the diaphragm has been moved past an intermediate dead center position by reduction or air pressure in the suction chamber.

7. The combination defined by claim 1, of which the syringe forms part oi a resilient closure for an opening in the wall of the suction chamber whereby alirnited movement will be imparted to the syringe to advance the position of its needle when pressure within the chamber is reduced.

8. The combination defined by claim 1, of which the suction chamber comprises a neck-hire portion into which extends the end of the syringe which carries the needle, and air sealing means closing the joint between the syringe and the surrounding wall oi the neck-like portion.

9. The combination defined by claim 1, of which the suction chamber has a neck-like portion into and through which the end of the syringe which carries the needle may be moved, on upwardly and outwardly flaring portion terminating in an annulardiaphragm seat above the neck-like portion, and a resilient diaphragm normolly in the form of a disk connected with the syringe and secured in said seat, the syringe being movable with the central portion of the diaphragm when pressure in the chamber is relcy contact of the diaphragm with the underlying flared wall of the cltiarnoer= MARIEQ DEMARCBE,

duced and the degree of movement being limited

US1934046A 1931-10-30 1932-03-24 Syringe for hypodermic medical injections Expired - Lifetime US1934046A (en)

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Cited By (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2743723A (en) * 1954-06-03 1956-05-01 George N Hein Hypodermic injection apparatus
US2945496A (en) * 1958-08-18 1960-07-19 Fosdal Alfred Dental instrument for immobilizing tissue
US3727614A (en) * 1971-05-13 1973-04-17 Merck & Co Inc Multiple dosage inoculator
US3905375A (en) * 1974-01-23 1975-09-16 Philip M Toyama Acupuncture needle
DE2551993A1 (en) * 1974-11-19 1976-07-15 Wolfgang Dr Med Wagner Sauginjektion with metering devices according to the principle of disposable
US4114619A (en) * 1975-11-21 1978-09-19 Wolfgang Wagner Automatic injecting apparatus
US4284077A (en) * 1974-11-19 1981-08-18 Wolfgang Wagner Suction injector having an adjustable dosing device
US4299219A (en) * 1979-12-17 1981-11-10 Norris Jr George P Intravenous needle insertion device
WO1982002835A1 (en) * 1981-02-24 1982-09-02 Edgar C Cohen Vacuum-compression injector
US4393870A (en) * 1974-11-19 1983-07-19 Wolfgang Wagner Suction injector
US4403609A (en) * 1981-02-24 1983-09-13 Cohen Edgar C Vacuum-compression injector
US4558698A (en) * 1984-03-01 1985-12-17 Dell Lawrence W O Laser canaliculostomy eye-treatment
US4664651A (en) * 1985-03-01 1987-05-12 The Procter & Gamble Company Subatmospheric method and apparatus for expanding blood vessels to facilitate puncture with a cannula
US4723940A (en) * 1983-06-15 1988-02-09 Akuaba B.V. Method and device to perforate, in particular to puncture a membranous member while utilizing vacuum fixation
US4769003A (en) * 1987-08-19 1988-09-06 Keith Stamler Wound irrigation splashback shield
US4898588A (en) * 1988-10-17 1990-02-06 Roberts Christopher W Hypodermic syringe splatter shield
US5088925A (en) * 1990-12-06 1992-02-18 Mason William E Instrument and method for administering an injectable anesthetic
US5478315A (en) * 1994-08-08 1995-12-26 Brothers Family Investments, L.C. Local anesthetic injection system
US5496290A (en) * 1994-11-23 1996-03-05 Ackrad Laboratories, Inc. Wound irrigation splash shield
DE19519281A1 (en) * 1994-09-16 1996-08-22 Wolfgang Dr Med Wagner Appts. for measuring metabolite and injecting drug as needed
US5853399A (en) * 1995-05-26 1998-12-29 Sasaki; Hiroshi Medical instruments and systems for puncturing an organ
US6063039A (en) * 1996-12-06 2000-05-16 Abbott Laboratories Method and apparatus for obtaining blood for diagnostic tests
US6132422A (en) * 1990-09-24 2000-10-17 Plc Medical Systems, Inc. Handpiece for transmyocardial vascularization heart-synchronized pulsed laser system
US6200291B1 (en) * 1998-01-08 2001-03-13 Antonio Di Pietro Device for controlling the penetration depth of a needle, for application to an injection syringe
US6254580B1 (en) * 1995-04-27 2001-07-03 Pal Svedman Suction blister sampling
US20010011171A1 (en) * 1999-10-14 2001-08-02 Alchas Paul G. Intradermal delivery device including a needle assembly
US6306104B1 (en) 1996-12-06 2001-10-23 Abbott Laboratories Method and apparatus for obtaining blood for diagnostic tests
US6340354B1 (en) * 1996-05-17 2002-01-22 Christopher L Rambin Automated compulsory blood extraction system
US20020068909A1 (en) * 1999-10-14 2002-06-06 Alchas Paul G. Intradermal needle
US20020095124A1 (en) * 1999-12-08 2002-07-18 Maria Palasis Lateral needle-less injection apparatus and method
US20030083619A1 (en) * 2001-10-26 2003-05-01 Massachusetts Institute Of Technology Microneedle transdermal transport device
US6558344B2 (en) 2001-02-09 2003-05-06 Westmed, Inc. Wound irrigation device
US20030093032A1 (en) * 2001-11-14 2003-05-15 Daniel Py Intradermal delivery device and method
US6569123B2 (en) 1999-10-14 2003-05-27 Becton, Dickinson And Company Prefillable intradermal injector
US6569143B2 (en) 1999-10-14 2003-05-27 Becton, Dickinson And Company Method of intradermally injecting substances
US20030199822A1 (en) * 1999-10-14 2003-10-23 Alchas Paul G. Intradermal needle
US6689103B1 (en) * 1999-05-07 2004-02-10 Scimed Life System, Inc. Injection array apparatus and method
US6689118B2 (en) 1999-10-14 2004-02-10 Becton Dickinson And Company Method of intradermally injecting substances
US20040116859A1 (en) * 1999-10-14 2004-06-17 Becton, Dickinson And Company Prefillable intradermal delivery device
US20040116865A1 (en) * 2002-10-07 2004-06-17 Henrik Bengtsson Needle insertion device
US20040147901A1 (en) * 2002-07-08 2004-07-29 Medical Instill Intradermal delivery device, and method of intradermal delivery
US20060018877A1 (en) * 2001-06-29 2006-01-26 Mikszta John A Intradermal delivery of vacccines and therapeutic agents
US20070265575A1 (en) * 2006-05-15 2007-11-15 Hillios Christopher H Injection aid and stability disk for syringe or insulin pen
EP1954332A2 (en) * 2005-11-21 2008-08-13 Becton, Dickinson and Company, Wagner, Jaconda Intradermal delivery device
US7473247B2 (en) 1999-10-14 2009-01-06 Becton, Dickinson And Company Intradermal delivery of vaccines and gene therapeutic agents via microcannula
US20090259179A1 (en) * 2006-05-15 2009-10-15 Hillios Christopher H Injection aid and stability disk for syringe or insulin pen
US20120157778A1 (en) * 2009-12-16 2012-06-21 Wheeler Steve Disposable shield for a medical tool
US8267890B2 (en) 2003-01-30 2012-09-18 Becton, Dickinson And Company Intradermal delivery device with contoured skin engaging surface geometry
US20150246183A1 (en) * 2012-10-20 2015-09-03 Biopreme Medical Technologies ,Inc. a corporation Needle-free injection devices, systems and methods
US9636468B2 (en) 2014-04-29 2017-05-02 Craig Tromborg Venipuncture assist device
WO2017088066A1 (en) * 2015-11-28 2017-06-01 Biopreme Medical Technologies Inc. Negative pressure injection device
US9682198B2 (en) 2003-08-28 2017-06-20 Becton, Dickinson And Company Intradermal injection device

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0103664B1 (en) * 1982-08-25 1986-12-30 Wagner, Wolfgang, Dr.med. Device for injection by the effect of vacuum on the skin
CA2159588A1 (en) * 1993-04-08 1994-10-27 Joseph Gross Intradermal injection device
WO2006017889A1 (en) * 2004-08-20 2006-02-23 Medigard Limited A medical device containing a vacuum chamber

Cited By (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2743723A (en) * 1954-06-03 1956-05-01 George N Hein Hypodermic injection apparatus
US2945496A (en) * 1958-08-18 1960-07-19 Fosdal Alfred Dental instrument for immobilizing tissue
US3727614A (en) * 1971-05-13 1973-04-17 Merck & Co Inc Multiple dosage inoculator
US3905375A (en) * 1974-01-23 1975-09-16 Philip M Toyama Acupuncture needle
US4393870A (en) * 1974-11-19 1983-07-19 Wolfgang Wagner Suction injector
DE2551993A1 (en) * 1974-11-19 1976-07-15 Wolfgang Dr Med Wagner Sauginjektion with metering devices according to the principle of disposable
US4284077A (en) * 1974-11-19 1981-08-18 Wolfgang Wagner Suction injector having an adjustable dosing device
US4114619A (en) * 1975-11-21 1978-09-19 Wolfgang Wagner Automatic injecting apparatus
US4299219A (en) * 1979-12-17 1981-11-10 Norris Jr George P Intravenous needle insertion device
US4403609A (en) * 1981-02-24 1983-09-13 Cohen Edgar C Vacuum-compression injector
WO1982002835A1 (en) * 1981-02-24 1982-09-02 Edgar C Cohen Vacuum-compression injector
US4421508A (en) * 1981-02-24 1983-12-20 Cohen Edgar C Vacuum-compression injector
US4723940A (en) * 1983-06-15 1988-02-09 Akuaba B.V. Method and device to perforate, in particular to puncture a membranous member while utilizing vacuum fixation
US4558698A (en) * 1984-03-01 1985-12-17 Dell Lawrence W O Laser canaliculostomy eye-treatment
US4664651A (en) * 1985-03-01 1987-05-12 The Procter & Gamble Company Subatmospheric method and apparatus for expanding blood vessels to facilitate puncture with a cannula
US4769003A (en) * 1987-08-19 1988-09-06 Keith Stamler Wound irrigation splashback shield
US4898588A (en) * 1988-10-17 1990-02-06 Roberts Christopher W Hypodermic syringe splatter shield
US6132422A (en) * 1990-09-24 2000-10-17 Plc Medical Systems, Inc. Handpiece for transmyocardial vascularization heart-synchronized pulsed laser system
US5088925A (en) * 1990-12-06 1992-02-18 Mason William E Instrument and method for administering an injectable anesthetic
US5478315A (en) * 1994-08-08 1995-12-26 Brothers Family Investments, L.C. Local anesthetic injection system
DE19519281A1 (en) * 1994-09-16 1996-08-22 Wolfgang Dr Med Wagner Appts. for measuring metabolite and injecting drug as needed
US5496290A (en) * 1994-11-23 1996-03-05 Ackrad Laboratories, Inc. Wound irrigation splash shield
US6254580B1 (en) * 1995-04-27 2001-07-03 Pal Svedman Suction blister sampling
US5853399A (en) * 1995-05-26 1998-12-29 Sasaki; Hiroshi Medical instruments and systems for puncturing an organ
US5882331A (en) * 1995-05-26 1999-03-16 Sasaki; Hiroshi Methods for puncturing an organ within a body cavity
US6340354B1 (en) * 1996-05-17 2002-01-22 Christopher L Rambin Automated compulsory blood extraction system
US6063039A (en) * 1996-12-06 2000-05-16 Abbott Laboratories Method and apparatus for obtaining blood for diagnostic tests
US6837858B2 (en) 1996-12-06 2005-01-04 Abbott Laboratories Method and apparatus for obtaining blood for diagnostic tests
US6283926B1 (en) 1996-12-06 2001-09-04 Abbott Laboratories Method and apparatus for obtaining blood for diagnostic tests
US6306104B1 (en) 1996-12-06 2001-10-23 Abbott Laboratories Method and apparatus for obtaining blood for diagnostic tests
US6200291B1 (en) * 1998-01-08 2001-03-13 Antonio Di Pietro Device for controlling the penetration depth of a needle, for application to an injection syringe
US6689103B1 (en) * 1999-05-07 2004-02-10 Scimed Life System, Inc. Injection array apparatus and method
US6494865B1 (en) 1999-10-14 2002-12-17 Becton Dickinson And Company Intradermal delivery device including a needle assembly
US20050113753A1 (en) * 1999-10-14 2005-05-26 Alchas Paul G. Intradermal needle
US20020068909A1 (en) * 1999-10-14 2002-06-06 Alchas Paul G. Intradermal needle
US9750897B2 (en) 1999-10-14 2017-09-05 Becton, Dickinson And Company Intradermal delivery device including a needle assembly
US7473247B2 (en) 1999-10-14 2009-01-06 Becton, Dickinson And Company Intradermal delivery of vaccines and gene therapeutic agents via microcannula
US20040116859A1 (en) * 1999-10-14 2004-06-17 Becton, Dickinson And Company Prefillable intradermal delivery device
US7241275B2 (en) 1999-10-14 2007-07-10 Becton, Dickinson And Company Intradermal needle
US7083599B2 (en) 1999-10-14 2006-08-01 Becton, Dickinson And Company Prefillable intradermal delivery device
US6843781B2 (en) * 1999-10-14 2005-01-18 Becton, Dickinson And Company Intradermal needle
US6569123B2 (en) 1999-10-14 2003-05-27 Becton, Dickinson And Company Prefillable intradermal injector
US20010012925A1 (en) * 1999-10-14 2001-08-09 Alchas Paul G. Intradermal delivery device including a needle assembly
US6776776B2 (en) 1999-10-14 2004-08-17 Becton, Dickinson And Company Prefillable intradermal delivery device
US20030199822A1 (en) * 1999-10-14 2003-10-23 Alchas Paul G. Intradermal needle
US20010011171A1 (en) * 1999-10-14 2001-08-02 Alchas Paul G. Intradermal delivery device including a needle assembly
US6689118B2 (en) 1999-10-14 2004-02-10 Becton Dickinson And Company Method of intradermally injecting substances
US6569143B2 (en) 1999-10-14 2003-05-27 Becton, Dickinson And Company Method of intradermally injecting substances
US7402155B2 (en) * 1999-12-08 2008-07-22 Boston Scientific Scimed, Inc. Injection apparatus for delivering therapeutic
US20020095124A1 (en) * 1999-12-08 2002-07-18 Maria Palasis Lateral needle-less injection apparatus and method
US6558344B2 (en) 2001-02-09 2003-05-06 Westmed, Inc. Wound irrigation device
US20060018877A1 (en) * 2001-06-29 2006-01-26 Mikszta John A Intradermal delivery of vacccines and therapeutic agents
US20030083618A1 (en) * 2001-10-26 2003-05-01 Massachusetts Institute Of Technology Transdermal transport device with an electrolytic actuator
US20030139727A1 (en) * 2001-10-26 2003-07-24 Massachusetts Institute Of Technology Transdermal transport device with suction
US7429258B2 (en) 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
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US7066922B2 (en) 2001-10-26 2006-06-27 Massachusetts Institute Of Technology Transdermal transport device with suction
US20030083619A1 (en) * 2001-10-26 2003-05-01 Massachusetts Institute Of Technology Microneedle transdermal transport device
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US20030083645A1 (en) * 2001-10-26 2003-05-01 Massachusetts Institute Of Technology Microneedle transport device
US7645263B2 (en) 2001-10-26 2010-01-12 Massachusetts Institute Of Technology Impedance sensor
US20080319392A1 (en) * 2001-10-26 2008-12-25 Angel Aimee B Microneedle transport device
US6971999B2 (en) 2001-11-14 2005-12-06 Medical Instill Technologies, Inc. Intradermal delivery device and method
US20030093032A1 (en) * 2001-11-14 2003-05-15 Daniel Py Intradermal delivery device and method
US20040147901A1 (en) * 2002-07-08 2004-07-29 Medical Instill Intradermal delivery device, and method of intradermal delivery
US7014625B2 (en) * 2002-10-07 2006-03-21 Novo Nordick A/S Needle insertion device
US20040116865A1 (en) * 2002-10-07 2004-06-17 Henrik Bengtsson Needle insertion device
US8267890B2 (en) 2003-01-30 2012-09-18 Becton, Dickinson And Company Intradermal delivery device with contoured skin engaging surface geometry
US9682198B2 (en) 2003-08-28 2017-06-20 Becton, Dickinson And Company Intradermal injection device
US9452257B2 (en) 2005-11-21 2016-09-27 Becton, Dickinson And Company Intradermal delivery device
US20110071494A1 (en) * 2005-11-21 2011-03-24 Clarke Richard P Intradermal Delivery Device
EP1954332A4 (en) * 2005-11-21 2014-10-08 Becton Dickinson Co Intradermal delivery device
EP1954332A2 (en) * 2005-11-21 2008-08-13 Becton, Dickinson and Company, Wagner, Jaconda Intradermal delivery device
US8419684B2 (en) * 2005-11-21 2013-04-16 Becton, Dickinson And Company Intradermal delivery device
US8361019B2 (en) 2006-05-15 2013-01-29 Hillios Christopher H Injection aid and stability disk for syringe or insulin pen
US20070265575A1 (en) * 2006-05-15 2007-11-15 Hillios Christopher H Injection aid and stability disk for syringe or insulin pen
US20090259179A1 (en) * 2006-05-15 2009-10-15 Hillios Christopher H Injection aid and stability disk for syringe or insulin pen
US7789856B2 (en) 2006-05-15 2010-09-07 Hillios Christopher H Injection aid and stability disk for syringe or insulin pen
US8663173B2 (en) * 2009-12-16 2014-03-04 Steve WHEELER Disposable shield for a medical tool
US20120157778A1 (en) * 2009-12-16 2012-06-21 Wheeler Steve Disposable shield for a medical tool
US20150246183A1 (en) * 2012-10-20 2015-09-03 Biopreme Medical Technologies ,Inc. a corporation Needle-free injection devices, systems and methods
US9636468B2 (en) 2014-04-29 2017-05-02 Craig Tromborg Venipuncture assist device
WO2017088066A1 (en) * 2015-11-28 2017-06-01 Biopreme Medical Technologies Inc. Negative pressure injection device

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FR729746A (en) 1932-07-30 grant
GB371305A (en) 1932-04-21 application
DE596981C (en) 1934-05-12 grant

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