US10217530B2 - Patient-specific cutting block and method of manufacturing same - Google Patents

Patient-specific cutting block and method of manufacturing same Download PDF

Info

Publication number
US10217530B2
US10217530B2 US14/729,505 US201514729505A US10217530B2 US 10217530 B2 US10217530 B2 US 10217530B2 US 201514729505 A US201514729505 A US 201514729505A US 10217530 B2 US10217530 B2 US 10217530B2
Authority
US
United States
Prior art keywords
bone
patient
orientation
fixing rod
method
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active, expires
Application number
US14/729,505
Other versions
US20150347710A1 (en
Inventor
Pierre Couture
Vincent MASSE
Anselm Jakob Neurohr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zimmer Inc
Original Assignee
Zimmer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US201462007124P priority Critical
Application filed by Zimmer Inc filed Critical Zimmer Inc
Priority to US14/729,505 priority patent/US10217530B2/en
Assigned to ZIMMER, INC. reassignment ZIMMER, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: MASSE, VINCENT, COUTURE, PIERRE, NEUROHR, Anselm Jakob
Publication of US20150347710A1 publication Critical patent/US20150347710A1/en
Application granted granted Critical
Publication of US10217530B2 publication Critical patent/US10217530B2/en
Application status is Active legal-status Critical
Adjusted expiration legal-status Critical

Links

Images

Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10Computer-aided planning, simulation or modelling of surgical operations
    • GPHYSICS
    • G06COMPUTING; CALCULATING; COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F19/00Digital computing or data processing equipment or methods, specially adapted for specific applications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10Computer-aided planning, simulation or modelling of surgical operations
    • A61B2034/101Computer-aided simulation of surgical operations
    • A61B2034/102Modelling of surgical devices, implants or prosthesis

Abstract

A patient-specific cutting assembly comprises a model file including geometrical data of a bone of the patient, of an intramedullary canal of the bone, and a planned orientation of a cutting block. A fixing rod is adapted to be longitudinally inserted in and extending partially from the intramedullary canal. A patient-specific cutting block is connectable to the fixing rod. The patient-specific cutting block includes a structure having a patient specific geometry corresponding to the model file of the patient, the structure configured to be connected to a portion of the fixing rod projecting from the bone in a unique coupling orientation. A cutting guide is connected to the structure, the cutting guide being in the planned orientation when the structure is connected to the portion of the fixing rod projecting from the bone.

Description

CROSS-REFERENCE TO RELATED APPLICATION

The present application claims priority on U.S. Provisional Patent Application No. 62/007,124, filed on Jun. 3, 2014, and incorporated herein by reference.

TECHNICAL FIELD

The application relates generally to orthopedic surgery involving the preparation of bones with a view to fixing an implant thereon and, more particularly, to devices and tools developed in planning for assisting orthopedic surgery.

BACKGROUND

Before posing an implant onto a bone, such as during a knee or hip replacement surgery, the bone needs to be prepared. The preparation of the bone includes removing diseased bone, for example, and making additional cuts so that the bone has a shape matching that of an inside of the implant, or drilling holes, placing guides, etc for providing guidance landmarks to an operator. For instance, in knee implant surgery, transverse and frontal cut planes are made to match surfaces of an implant.

Determination of alterations to the bone, of the portions of the bone that need to be removed, of guides to be placed may be done prior to surgery using images of the bone of the patient, in pre-operative planning. The pre-operative planning may help in ensuring the precision and accuracy of the surgery, as bone alterations will influence the fit of the implant onto the bone. For example, a bone that has been improperly cut may lead to improper implant placement, resulting in conditions such as leg length discrepancy, improper gait, premature implant wear, and pain, to name a few.

SUMMARY

Therefore, in accordance with a first embodiment of the present disclosure, there is provided a method of creating a model of a patient-specific structure of a cutting block, the cutting block used for assisting an operator in cutting at least one plane in a bone of a patient, the method comprising: obtaining geometrical data of a bone and of an intramedullary canal of the bone; determining a penetration of a fixing rod to be inserted in and extending partially out from an intramedullary canal of the bone, the penetration based on the geometrical data of the intramedullary canal of the bone and on a geometry of the fixing rod; determining an orientation of a portion of the fixing rod projecting out of the bone relative to the bone based on the geometrical data of the bone, on the geometry of the fixing rod and on the penetration; and creating the model of the patient-specific structure of the cutting block using the geometrical data of the bone, a desired position and orientation of the at least one cut plane on the bone, and the orientation of the portion of the fixing rod projecting out of the bone.

Further in accordance with the first embodiment, creating the model comprises determining an orientation of a bore to be formed through the patient-specific structure, the bore being adapted to connect to the portion of the fixing rod in a unique coupling orientation.

Still further in accordance with the first embodiment, determining the orientation of the portion of the fixing rod projecting out of the bone relative to the bone comprises determining an orientation of the portion relative to a bone axis as the geometrical data of the bone.

Still further in accordance with the first embodiment, obtaining geometrical data of a bone comprises obtaining a mechanical axis of the bone.

Still further in accordance with the first embodiment, determining the orientation of the portion relative to the bone axis comprises obtaining a spatial angle between an axis of the portion of the fixing rod and the bone axis.

Still further in accordance with the first embodiment, instructions are created based on the model of the patient-specific structure for manufacturing the patient-specific structure.

Still further in accordance with the first embodiment, the patient-specific structure is manufactured based on the instructions.

Still further in accordance with the first embodiment, the desired position and orientation of the cutting plane of the bone is determined using a model of an implant.

Still further in accordance with the first embodiment, creating the model comprises modelling patient-specifically an attachment of the cutting guide to the patient-specific structure based on an orientation of the patient-specific structure relative to the bone and of geometrical data of the bone.

Still further in accordance with the first embodiment, instructions are created based on the patient-specific attachment model for manufacturing the patient-specific cutting attachment.

Still further in accordance with the first embodiment, the patient-specific cutting attachment is manufactured based on the instructions.

In accordance with a second embodiment of the present disclosure, there is provided a patient-specific cutting assembly, the assembly comprising: a model file including geometrical data of a bone of the patient, of an intramedullary canal of the bone, and a planned orientation of a cutting block; a fixing rod adapted to be longitudinally inserted in and extending partially from the intramedullary canal; and a patient-specific cutting block connectable to the fixing rod, the patient-specific cutting block including at least: a structure having a patient specific geometry corresponding to the model file of the patient, the structure configured to be connected to a portion of the fixing rod projecting from the bone in a unique coupling orientation; and a cutting guide connected to the structure, the cutting guide being in the planned orientation when the structure is connected to the portion of the fixing rod projecting from the bone.

Further in accordance with the second embodiment, the structure has a bore extending through opposed first and second faces thereof, the bore having a diameter allowing the fixing rod to be inserted thereinto, the bore being formed in the structure at an orientation based on the model file.

Still further in accordance with the second embodiment, an orientation of the bore in the structure is based on a predetermined bone axis.

Still further in accordance with the second embodiment, the predetermined bone axis is a mechanical axis of the bone.

Still further in accordance with the second embodiment, a face of the structure is adapted to abut the bone, the face of the structure has a shaped that is a negative of a surface of the bone obtained as the geometrical data of the bone of the patient.

Still further in accordance with the second embodiment, the fixing rod has a geometry that is a negative of an inner surface of the intramedullary canal obtained as the geometrical data of the intramedullary canal.

In accordance with a third embodiment of the present disclosure, there is provided a method of cutting a bone of a patient in preparation of placement of an implant onto the bone, the method comprising: inserting a fixing rod longitudinally in an intramedullary canal of the bone with a portion of the fixing rod extending outside the bone; connecting a patient-specific structure of a cutting block onto the portion of the fixing rod extending outside the bone and placing a cutting guide of the patient-specific cutting block in abutment with the bone in a unique coupling orientation; and cutting the bone with the cutting guide.

Further in accordance with the third embodiment, connecting the patient-specific structure comprises anchoring the patient-specific structure to the bone and removing the fixing rod.

In another aspect, there is provided a method of manufacturing a patient-specific structure of a cutting block, the structure providing a support to a cutting guide for cutting a plane in a bone of a patient, the method comprising: predicting an orientation of a fixing rod to be inserted in and extending partially from an intramedullary canal of the bone, the prediction of the orientation of the fixing rod being based on a known orientation of the intramedullary canal of the bone; determining an orientation of the fixing rod relative to a bone axis, the bone axis being determined using data of the bone, the determination of the orientation of the fixing rod being achieved by modelling the fixing rod inserted in the intramedullary canal; and modelling the patient-specific structure of the cutting block for manufacture thereof, the modelling including modelling a bore to be formed through the patient-specific structure, the bore being adapted to connect to the fixing rod, the bore having an orientation relative to the patient-specific structure dependent on the orientation of the fixing rod relative to the bone axis.

In yet another aspect, there is provided a patient-specific cutting assembly, the assembly comprising: a fixing rod adapted to be longitudinally inserted in and extending partially from an intramedullary canal of a bone of a patient; and a patient-specific cutting block connectable to the fixing rod, the patient-specific cutting block including: a structure comprising: opposed first and second faces; and a bore extending through opposed first and second faces, the bore having a diameter allowing the fixing rod to be inserted thereinto, the bore being formed in the structure at an orientation based on an orientation of the fixing rod should have when inserted in the intramedullary canal and on an orientation of a predetermined bone axis, the predetermined bone axis being determined using data of the bone, the structure when inserted into the fixing rod having a fixed orientation; and a cutting guide connected to the structure, the cutting guide being parallel to the opposed first and second faces, the cutting guide being at a distance from the structure based on an implant selected for the bone of the patient.

In yet another aspect, there is provided a method of cutting a bone of a patient in preparation of placement of an implant onto the bone, the method comprising: inserting a fixing rod longitudinally in an intramedullary canal of the bone with a portion of the fixing rod extending outside the bone; inserting a patient-specific structure of a cutting block onto the portion of the fixing rod extending outside the bone and placing a cutting guide of the patient-specific cutting block in abutment with the bone, the structure having opposed first and second faces and a bore therethrough, an orientation of the bore relative to the structure being predetermined as a function of an orientation of the fixing rod relative to the intramedullary canal and of a bone axis, the bone axis being predetermined using data of the bone, the bore providing a fixed patient-specific orientation of the structure relative to the bone, the cutting guide extending from the first face at a predetermined distance, the predetermined distance being dependent on the implant selected for the bone; and cutting the bone with the cutting guide.

DESCRIPTION OF THE DRAWINGS

Reference is now made to the accompanying figures in which:

FIG. 1 is a schematic view of a human femur;

FIG. 2 is an X-ray image of a femur;

FIG. 3 is a schematic view of a patient-specific cutting block for the femur of FIG. 1;

FIG. 4 is a schematic view of a fixing rod of the patient-specific cutting block of FIG. 3 inserted in the intramedullary canal of the femur of FIG. 1;

FIG. 5 is a schematic view of the femur of FIG. 1 shown with the patient-specific cutting block of FIG. 3 assembled to the fixing rod;

FIG. 6 is a schematic view of FIG. 5 shown from a different angle;

FIG. 7 is a flow chart of a method of manufacturing the patient-specific cutting block of FIG. 3; and

FIG. 8 is a flow chart of a method of cutting the femur of FIG. 1 with the patient-specific cutting block of FIG. 3.

DETAILED DESCRIPTION

The present disclosure will be made with reference to a human femur and a knee joint replacement surgery. It should be however understood that the disclosed devices and methods could be applied to human or animal bones other than the femur, to bone models, and implant surgeries other than knee joint replacement surgeries. Example of such bones include tibia, humerus and ulna, among others. The femur discussed herein being a 3-D component, spatial references will be made to “orientations”. By orientation, it should be understood spatial orientation defined by the three Euler angles (θ,φ,ψ) relative to a fixed frame of the bone. Also, references within this specification will be made to frontal plane (a.k.a. coronal plane), transverse plane (a.k.a. horizontal/vertical plane), and sagittal plane as commonly used as medical terminology.

With reference to FIG. 1, a human femur 10 is schematically shown along a frontal plane F. The femur 10 is the thigh bone and the longest bone in the body. A lower end 12 joins the tibia (not shown) to form the knee joint, while an upper end 14 is rounded into a femoral head 16 that fits into the acetabulum of the pelvis 19 (shown in FIG. 2) to form the hip joint. Just below the femoral head 16 is the femoral neck 18. The lower end 12 includes a lateral condyle 20 and a medial condyle 22, with a midpoint midway between the lateral condyle 20 and the medial condyle 22.

The femur 10, as other bones in the human body, is made of hard material, known as cortical bone, compact bone, forming the cortex of the bone. An inside of the bone contains a softer material called bone marrow. The bone marrow is contained in a portion called intramedullary canal 24 (shown in phantom in FIG. 1). The intramedullary canal 24 is non visible from the outside of the bone but can be seen on various medical imaging techniques such as X-rays used for example with magnetic resonance imagery to perform a 3-D reconstruction of the bone. The bone marrow being made of a material different from that of a rest of the bone, it may be contrasted out on the images. FIG. 2 shows an example of such imaging which enable to detect and define the intramedullary canal 24 in the bone, the bone portions being in a lighter shade of gray than the bone marrow. Hence, the geometry of the intramedullary canal 24 may be evaluated from the images, such as the X-rays.

The femur 10 is to be prepared in view of a knee joint replacement surgery by altering its knee-joint extremity in order to receive an implant (not shown) thereon. The lower end 12 is to be partially resurfaced to match a geometry of the implant for the implant to abut against the resurfaced knee joint in a predetermined position. The device and methods described herein allow tools such as a cutting block (a.k.a., positioning block, cut block, universal positioning block or tool) to be fabricated in part or as a whole as patient specific. The cutting block and other instruments described herein are said to be patient-specific, in that their geometries are modeled based on a planning for every patient's unique anatomy, using imaging techniques. Stated differently, the instruments such as the cutting block described hereinafter are developed subsequent to pre-operative steps by which a patient's anatomy is modeled and the implant position is defined. Hence, the instruments such as the cutting block described hereinafter have an identity related to a patient, and are most likely inadequate for being used with other patients, whereby the instruments are typically a one-time use instrument. Accordingly, the patient-specific instruments each have a model file of non-transient format which features a two-dimensional or three-dimensional model of the patient's anatomy resulting from pre-operative imaging. The specific geometry of the components of the patient-specific instruments are directly related to the contents of the model file. This means practically that data of the actual bone to be altered is used to manufacture portions or an entirety of the cutting block which once positioned relative to the femur 10, will be at a fixed predetermined and planned orientation and will guide a patient-specific cut of the femur 10.

Turning now to FIGS. 3 to 6, a patient-specific cutting assembly 30 includes a model file 31, a fixing rod 32 insertable in the intramedullary canal 24 of the femur 10, and a patient-specific cutting block 34 for cutting off portions of the bone, in preparation for implanting. The fixing rod 32 connects the patient-specific cutting block 34 to the femur 10.

The fixing rod 32 is a rigid rod selected to be inserted inside the intramedullary canal 24 of the femur 10. To that end, the fixing rod 32 is made of a biocompatible material. Examples of biocompatible materials include medical grade aluminum and medical grade titanium alloys. In order to be inserted inside the intramedullary canal 24, the fixing rod 32 is chosen to have a diameter smaller than that of the intramedullary canal 24 and to have a length allowing a portion to extend outside the femur 10. The diameter of the fixing rod 32 may not be chosen too small that the fixing rod 32 may radially displace in the intramedullary canal 24. At the same time, the diameter of the fixing rod 32 may not be chosen to large that the fixing rod 32 may alter the femur 10. Similarly, the length of the fixing rod 32 may not be chosen too short that the fixing rod 32 may not be secured in the intramedullary canal 24 and the cutting block 34 moves. The fixing rod 32, once inserted, should have a portion 32 a extending from the femur 10 in order to attach a structure 36 of the cutting block 34 thereonto. The fixing rod 32 may be selected from a pool of already available rods or may be custom made to have a patient-specific geometry corresponding to that of the intramedullary canal 24. Hence, the fixing rod 32 may be one of the patient-specific instruments resulting from the pre-operative planning. In order to select the fixing rod 32, data on the femur 10 is analysed to determine a shape and size of the intramedullary canal 24. In one example, X-rays, such as the one of FIG. 2, are used to delimitate walls of the intramedullary canal 24, from which can be deduced a diameter and a length of the intramedullary canal 24. For instance, frontal and transverse X-rays may suffice in evaluating the geometry of the intramedullary canal 24 and predict a fit of the fixing rod 32 therein. In another example, a 3-D model of the intramedullary canal is created, and may be part of the model file 31, this embodiment being particularly useful when the fixing rod 32 has a geometry specific to the patient and thus shaped for custom and unique penetration in the intramedullary canal 24.

The patient-specific cutting block 34 includes the structure 36 to which one or more cutting guides 37 may be connected. Each of the cutting guide 37 has a cut slot, in which a blade may be inserted to guide in cutting the femur 10 along a plane of the cut slot. Other accessories may also be connected to the structure 36, such as drill guides, mill guides, reamer guides, in similar fashion to the cutting guide 37. The cutting guide 37 is removably connected to the structure 36 by an attachment 35. The cutting guide 37 and/or the attachment 35 may be selected from a pool of already made components or be patient-specific (i.e. manufactured based on patient's data), as a monolithic component with or without the structure 36. The attachment 35 may be connected to different locations on the structure 36 so as to orient cutting guide 37 and other alteration accessories to cut through different planes, such as the planes described above, or alter the bone at selected locations. In yet another embodiment, the cutting guide 37 are cut slots defined directly in the structure 36. According to another embodiment, temporary anchor holes are provided in the structure 36 to secure same to the femur F, after it has been positioned and oriented as planned relative to the femur F. This may allow the removal of the fixing rod 32, as the rod 32 could otherwise be in the way of cut blades. For example, lateral walls may project from the structure 36 for securing the structure 36 to medial/lateral portions of the femur F, which medial/lateral portions are not resurfaced during knee joint surgery.

In one non-limiting embodiment, the structure 36 has opposed first and second faces 38, 39. The second face 39 may abut the bone when installed onto the fixing rod 32. In order to provide a unique coupling orientation, the second face 39 may have a patient specific surface, being a negative of the bone it will abut, for unique complementary contact. Alternatively, the structure 36 may have abutments positioned as a function of the planning, again to ensure the unique coupling orientation. The structure 36 may made of a biocompatible material which may be same or different than the one used for the fixing rod 32. The structure 36 may have dimensions similar to that of the lower end 12 of the femur 10 against which it will abut (shown in FIG. 5). The structure 36 may be selected from a pool of already available structures or may be custom made based on preoperative data, such as model file 31, representative of the femur 10 it will be put onto.

The structure 36 includes a bore 40 (shown in FIG. 3) which is designed to position the structure 36 in a predetermined orientation to, in turn, position the cutting guide 37 along a desired cutting plane. The positioning of the bore 40 in the structure 36 may therefore be patient specific, such that the assembly of the structure 36 onto the fixing rod 32 via the bore 40 results in a planned unique coupling orientation of the structure 36 relative to the bone. When the patient-specific cutting assembly 30 is assembled onto the femur 10, the bore 40 receives the fixing rod 32. As such, the bore 40 is dimensioned to have a diameter larger than that of the fixing rod 32, for sliding movement thereon. In one embodiment, the diameter of the bore 40 is slightly larger than that of the fixing rod 32 to reduce any play therebetween. In addition, to provide the desired orientation of the structure 36, the bore 40 is disposed at a predetermined orientation relative to the opposed faces 38, 39 as mentioned above. It is also contemplated to provide a unique coupling orientation joint between the portion 32 a of the fixing rod 32 and the bore 40, to reach the unique coupling orientation of the structure 36 relative to the bone. In the embodiment shown in the figures, the predetermined orientation corresponds to an angle α between the bore 40 and the opposed faces 38, 39. The angle α shown in the figures is an absolute angle. It may be decomposable into two angles projected respectively on the frontal plane F and a sagittal plane S (shown in FIG. 1). The angle α is chosen based on an orientation of the fixing rod 32 relative to the femur 10 when the fixing rod 32 is inserted in the intramedullary canal 24, i.e. axis A1, and on an orientation of a predetermined bone axis A2, for instance combining the angles along the transverse plane T and the frontal plane F. The axes A1 and A2 are shown in FIG. 4.

The axis A1 may be defined as the axis of the fixing rod 32 when the fixing rod 32 is inserted in the intramedullary canal 24. The orientation of the axis A1 may thus be determined preoperatively, after modelling the insertion of the fixing rod 32 into the intramedullary canal 24 using data of the femur 10 from, for example, pre-operative radiographic images, to determine an orientation of the intramedullary canal 24 and data of the selected fixing rod 32. In another example, the axis A1 may be defined as an axis passing at equidistance between walls of the intramedullary canal 24.

The axis A2 may be defined as an axis based on loads experienced by the femur 10 during normal use and/or connections to the other bones (pelvis and knee). For example, the axis A2 may be defined as the mechanical axis passing through the center of the femoral head 16 and the midpoint 21 (shown in FIG. 4) between the condyles 20, 22. Other definitions of the axis A2 are contemplated, as desired by the user of the system. The determination of the axis A2 may be using data of the bone, such as the X-rays or a 3-D model of the bone. Virtual modelling of the bone 10 and the loads may also be used to determine the axes A1 and A2.

The axes A1 and A2 are determined in a non-invasive pre-operative manner and before manufacturing the structure 36 so that the bore 40 may be formed in the structure 36 at the angle α desired such that once the fixing rod 32 and structure 36 are in place on the femur 10, the structure 36 provides the desired orientation for the cutting guide 37, simply by positioning the structure 36 on the fixing rod 32, without the subsequent need for intraoperative navigation to adjust the orientation of the structure 36.

In a femoral knee embodiment, the structure 36 may accommodate the attachment 35 in three distinct positions, so that the cutting guide 37 may be positioned to cut the femur 10 along the three different planes: transverse, frontal anterior and frontal posterior. The structure 36 could accommodate more or less than three distinct cutting positions, for examples by providing drill positions, and defines planes other than transverse and frontal. The planes corresponds to planes defined in the implant and through which the implant and the femur 10 will connect in coplanar fashion, and may include oblique planes. In the embodiment shown in the figures, the cutting guide 37 is disposed so as to perform cuts parallel to a transverse plane T. As shown in FIG. 5, the transverse plane T is parallel to the faces 38, 39 of the structure 36. The cutting guide 37 is disposed at a distance d (shown in FIG. 3) from the face 39 which is determined based on the implant selected (i.e. depth of the inside of the implant). The cutting guide 37 could be disposed along another plane after the cut along the transverse plane T. The other plane may be a plane perpendicular to the transverse plane T or at an angle with the transverse plane T. As such, the cutting guide 37 can be used to sequentially cut along different predetermined planes.

Turning now to FIG. 7, a method 50 of manufacturing the patient-specific cutting block 30 will be described. The method 50 is performed before surgery in order to provide a patient-specific bone cutting assembly or a patient-specific portion thereof.

According to 51, bone data is obtained, using imaging of the bone. For example, a model of the bone may be created. The bone data may include size, diameter and/or geometry of the intramedullary canal 24, and a model of the bone surface to be resurfaced, as well as axes, such as a mechanical axis of the femur F in the case of knee joint surgery.

The method 50 has a step 52 of determining the orientation of the fixing rod 32 as inserted in the intramedullary canal 24. The geometry of the intramedullary canal 24 may be determined from the bone data obtained at 51. Based on the dimension and shape of the intramedullary canal 24, a fixing rod 32 may be selected as described above. Alternatively, a fixing rod 32 specific to the patient may be designed in accordance with the geometry of the intramedullary canal 24 of the patient, ensure a specific and unique-orientation fit of the fixing rod 32 in the intramedullary canal 24. Modelling can be used to virtually insert the selected fixing rod 32 into the intramedullary canal 24 in order to determine an orientation of the portion 32 a of the fixing rod 32 relative to the surrounding bone, for instance by determining axis A1. Other techniques can be used to determine the orientation of the portion 32 a relative to femur F.

From step 52, the method 50 goes to step 54 where the orientation of the cut planes are determined. For example, the orientation of the cut planes may be based on the bone axis A2 (mechanical axis) based on an operator's preference in planning surgery, for instance in a fashion described above. For example, it may be desired that the bone axis A2 be normal to a transverse cut plane. Likewise, the anterior frontal and posterior frontal planes may be parallel to the bone axis A2, and perpendicular to the transverse cut plane. The bone axis A2 may have been drawn onto radiographic images or been virtually modelled onto a 3-D model of the femur 10 in step 51. Other ways to determine the orientation of the cut planes and/or indicate the bone axis A2 are contemplated. Then, the orientation of the bone axis A2 and of the fixing rod 32 inside the intramedullary canal 24 may be used to determine an orientation between them, for example using the angle α described above.

From step 54, the method 50 goes to step 56, where the patient-specific cutting block 30 is modeled based on the orientations of the axis A1 and A2 and on the orientation of the cut planes. As such, the method 50 may take into consideration the size of the implant that will be used. A portion (such as the structure 36) of the cutting block 30 or the entirety of the cutting block 30 can be modeled to be patient-specific. In the example below, the structure 36 is modeled to be patient specific. The model includes the bore 40 formed in the structure 36 at an angle related to the angle α, which indicates the orientation between the axes A1 and A2 and is thus patient specific as it was determined based on preoperative planning specific to the client. In one embodiment, the angle α corresponds to the orientation between the axis A1 and the axis A2 in the transverse plane and the frontal plane. However, modelling at step 54 may include only knowing relative orientations of the parts so as to select the structure 36 and form the bore 40 in accordance to the axis A1 and A2, and not necessarily 3-D modelling of the structure 36.

The method 50 may be followed by the steps of creating instructions based on the model of the structure 36 for manufacturing the structure 36, and manufacturing the structure 36 based on the instructions. The method 50 may also include selecting from a pool of attachments 35 or manufacturing the attachments 35 based on patient's data such that the cutting guide 37 is at the distance d according to the implant selected, the distance d being determined by the dimensions of the implant. Similarly, the cutting guide 37 may be selected form a pool of cutting guides 37 or manufactured based on patient's data and on the distance d. The implant may be selected based on patient data, and the implant characteristics may be provided so that the distance d may be determined.

Once the structure 36 is manufactured, the assembly of the structure 36, attachment 35 and cutting guide 32, if required, is performed intraoperatively.

Turning now to FIG. 8, a method 60 of cutting the femur 10 with the patient-specific cutting block 30 in preparation of placement of the implant thereonto will be described.

At step 62, with the femur resected or machined to expose the intramedullary canal, the fixing rod 32 is inserted longitudinally in the intramedullary canal 24 of the femur 10 such that the portion 32 a of the fixing rod 32 extends outside the bone in the predicted manner.

At step 64, once the fixing rod 32 is inserted, the structure 36 may be installed onto the portion 32 a, for instance until abutment with the lower end 12 of the femur 10. The structure 36, once inserted onto the fixing rod 32, may be rotated around the fixing rod 32 until being blocked in a desired position. For this purpose, the structure 36 may have abutments positioned to ensure that the structure 36 has a unique coupling orientation of abutment against the bone when installed onto the portion 32 a. In one embodiment, the structure 36 is rotated so as to abut the posterior condyles. Other ways to position the structure 36 relative to the bone 10 are contemplated, such as complementary mating or abutment. The bore 40 provides a fixed patient-specific orientation of the structure 36 relative to the bone 10. As such, when the structure 36 is inserted, there may be no adjustment of the orientation of the structure 36 relative to the femur 10, as the structure 36 may necessarily adopt the unique coupling orientation. It may be necessary to rotate the structure 36 about the portion 32 a to ensure that a desired orientation is reached. For this purpose, the structure 36 may have a visual marker to be aligned with the midpoint 21 (FIG. 4), or may have a projecting abutment that will abut against the bone in the predicted orientation, as alternatives to the patient specific second face 39. For instance, the attachment 35 may be positioned onto the structure 36 and the cutting guide 37 placed in abutment with the bone, to serve as the means for aligning the structure 36 in a degree of freedom of orientation that is about the axis of the fixing rod 32, if the portion 32 a is round in cross-section. Other examples to set the rotation include one or more visual markers aligned with bony landmarks (e.g. epicondylar axis), surfaces on the patient-specific cutting block 30 matching a shape of the bone 10, abutment against the bone or cartilage, and abutment against posterior condyles.

In step 66, the bone may be cut along the transverse plane T (or another plane, depending on the cutting guide 37 position, as discussed above). The attachment 35 positions the cutting guide 37 at the distance d predetermined in function of the implant. It may be required that the structure 36 be pinned down to the bone, and the fixing rod 32 be removed, prior to cutting the bone.

The above device and methods allow to adapt the cutting tools to each patient so as to provide more precise cutting and therefore better fit of the implant. The above methods may be performed with already existing images of the bones or with new images of the bone. The patient-specific cutting block may be manufactured using a pool of structures, rods and cutting attachments and customising the bore orientation and the distance between the cutting guide and the structure.

The above description is meant to be exemplary only, and one skilled in the art will recognize that changes may be made to the embodiments described without departing from the scope of the invention disclosed. Other modifications which fall within the scope of the present invention will be apparent to those skilled in the art, in light of a review of this disclosure, and such modifications are intended to fall within the appended claims.

Claims (12)

The invention claimed is:
1. A method of creating a model of a patient-specific structure of a cutting block, the cutting block used for assisting an operator in cutting at least one plane in a bone of a patient, the method comprising:
obtaining geometrical data of a bone and of an intramedullary canal of the bone;
determining a penetration of a fixing rod to be inserted in and extending partially out from an intramedullary canal of the bone, the penetration based on the geometrical data of the intramedullary canal of the bone and on a geometry of the fixing rod;
determining an orientation of a portion of the fixing rod projecting out of the bone relative to the bone based on the geometrical data of the bone, on the geometry of the fixing rod and on the penetration; and
creating the model of the patient-specific structure of the cutting block using the geometrical data of the bone, a desired position and orientation of the at least one cut plane on the bone, and the orientation of the portion of the fixing rod projecting out of the bone, the model of the patient-specific structure being three dimensional and having a unique coupling orientation in which the cutting block is on the portion of the fixing rod projecting out of the bone and the cutting block contacts the bone in blocked abutment planned pre-operatively, a cut slot of the cutting block being aligned with the at least one cut plane on the bone at said unique coupling orientation.
2. The method as defined in claim 1, wherein creating the model comprises determining an orientation of a bore to be formed through the patient-specific structure, the bore being adapted to connect to the portion of the fixing rod in a unique coupling orientation.
3. The method as defined in claim 1, wherein determining the orientation of the portion of the fixing rod projecting out of the bone relative to the bone comprises determining an orientation of the portion relative to a bone axis as the geometrical data of the bone.
4. The method as defined in claim 3, wherein obtaining geometrical data of a bone comprises obtaining a mechanical axis of the bone.
5. The method as defined in claim 3, wherein determining the orientation of the portion relative to the bone axis comprises obtaining a spatial angle between an axis of the portion of the fixing rod and the bone axis.
6. The method as defined in claim 1, further comprising creating instructions based on the model of the patient-specific structure for manufacturing the patient-specific structure.
7. The method as defined in claim 6, further comprising manufacturing the patient-specific structure based on the instructions.
8. The method as defined in claim 1, further comprising determining the desired position and orientation of the cutting plane of the bone using a model of an implant.
9. The method as defined in claim 1, wherein creating the model comprises modelling patient-specifically a patient-specific cutting attachment of the cutting block to the patient-specific structure based on an orientation of the patient-specific structure relative to the bone and of geometrical data of the bone.
10. The method as defined in claim 9, further comprising creating instructions based on the model of the patient-specific cutting attachment for manufacturing the patient-specific cutting attachment.
11. The method as defined in claim 10, further comprising manufacturing the patient-specific cutting attachment based on the instructions.
12. The method as defined in claim 1, wherein creating the model comprises defining an abutment surface of the patient-specific structure with a negative surface matching a geometry of the bone for unique complementary contact in said unique coupling orientation.
US14/729,505 2014-06-03 2015-06-03 Patient-specific cutting block and method of manufacturing same Active 2036-11-07 US10217530B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US201462007124P true 2014-06-03 2014-06-03
US14/729,505 US10217530B2 (en) 2014-06-03 2015-06-03 Patient-specific cutting block and method of manufacturing same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14/729,505 US10217530B2 (en) 2014-06-03 2015-06-03 Patient-specific cutting block and method of manufacturing same
US16/248,051 US20190148022A1 (en) 2014-06-03 2019-01-15 Patient-specific cutting block and method of manufacturing same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US16/248,051 Division US20190148022A1 (en) 2014-06-03 2019-01-15 Patient-specific cutting block and method of manufacturing same

Publications (2)

Publication Number Publication Date
US20150347710A1 US20150347710A1 (en) 2015-12-03
US10217530B2 true US10217530B2 (en) 2019-02-26

Family

ID=54702106

Family Applications (2)

Application Number Title Priority Date Filing Date
US14/729,505 Active 2036-11-07 US10217530B2 (en) 2014-06-03 2015-06-03 Patient-specific cutting block and method of manufacturing same
US16/248,051 Pending US20190148022A1 (en) 2014-06-03 2019-01-15 Patient-specific cutting block and method of manufacturing same

Family Applications After (1)

Application Number Title Priority Date Filing Date
US16/248,051 Pending US20190148022A1 (en) 2014-06-03 2019-01-15 Patient-specific cutting block and method of manufacturing same

Country Status (5)

Country Link
US (2) US10217530B2 (en)
EP (1) EP3151759A4 (en)
CN (1) CN106456192A (en)
CA (1) CA2947773A1 (en)
WO (1) WO2015187822A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9622820B2 (en) * 2012-05-03 2017-04-18 Siemens Product Lifecycle Management Software Inc. Feature-driven rule-based framework for orthopedic surgical planning

Citations (161)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4841975A (en) 1987-04-15 1989-06-27 Cemax, Inc. Preoperative planning of bone cuts and joint replacement using radiant energy scan imaging
US5098383A (en) 1990-02-08 1992-03-24 Artifax Ltd. Device for orienting appliances, prostheses, and instrumentation in medical procedures and methods of making same
US5179915A (en) 1992-01-06 1993-01-19 Osteonics Corporation Anatomically matching intramedullary alignment rod
US5490854A (en) 1992-02-20 1996-02-13 Synvasive Technology, Inc. Surgical cutting block and method of use
US5768134A (en) 1994-04-19 1998-06-16 Materialise, Naamloze Vennootschap Method for making a perfected medical model on the basis of digital image information of a part of the body
US5871018A (en) 1995-12-26 1999-02-16 Delp; Scott L. Computer-assisted surgical method
US5916219A (en) 1997-02-10 1999-06-29 Matsuno; Shigeo Tibial plateau resection guide
US5928240A (en) 1995-02-16 1999-07-27 Johnson; Lanny L. Apparatus for forming a centered bore for the femoral stem of a hip prosthesis
US20030055502A1 (en) 2001-05-25 2003-03-20 Philipp Lang Methods and compositions for articular resurfacing
US20030216669A1 (en) 2001-05-25 2003-11-20 Imaging Therapeutics, Inc. Methods and compositions for articular repair
CA2501041A1 (en) 2002-10-07 2004-04-22 Conformis, Inc. Minimally invasive joint implant with 3-dimensional geometry matching the articular surfaces
CA2505371A1 (en) 2002-11-07 2004-05-27 Conformis, Inc. Methods for determining meniscal size and shape and for devising treatment
CA2506849A1 (en) 2002-12-04 2004-06-17 Konstantinos Tsougarakis Fusion of multiple imaging planes for isotropic imaging in mri and quantitative image analysis using isotropic or near-isotropic imaging
US20040204760A1 (en) 2001-05-25 2004-10-14 Imaging Therapeutics, Inc. Patient selectable knee arthroplasty devices
US20040236424A1 (en) 2001-05-25 2004-11-25 Imaging Therapeutics, Inc. Patient selectable joint arthroplasty devices and surgical tools facilitating increased accuracy, speed and simplicity in performing total and partial joint arthroplasty
US20050203524A1 (en) 2004-03-04 2005-09-15 Penenberg Brad L. Bone preserving total hip arthroplasty using autograft
US20050234461A1 (en) 2001-05-25 2005-10-20 Burdulis Albert G Jr Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty
US20050267584A1 (en) 2001-05-25 2005-12-01 Burdulis Albert G Jr Patient selectable knee joint arthroplasty devices
CN1728976A (en) 2002-10-07 2006-02-01 康复米斯公司 Minimally invasive joint implant with 3-dimensional geometry matching the articular surfaces
US20060111722A1 (en) 2004-11-19 2006-05-25 Hacene Bouadi Surgical cutting tool
AU2006297137A1 (en) 2005-09-30 2007-04-12 Conformis Inc. Joint arthroplasty devices
US20070083266A1 (en) 2001-05-25 2007-04-12 Vertegen, Inc. Devices and methods for treating facet joints, uncovertebral joints, costovertebral joints and other joints
WO2007062103A1 (en) 2005-11-23 2007-05-31 Conformis, Inc. Implant grasper
AU2007202573A1 (en) 2001-05-25 2007-06-28 Conformis, Inc. Methods and compositions for articular resurfacing
US20070157783A1 (en) 2006-01-06 2007-07-12 Tung-Lung Chiang Paper cutter
WO2007092841A2 (en) 2006-02-06 2007-08-16 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
AU2007226924A1 (en) 2006-03-21 2007-09-27 Conformis, Inc. Interpositional joint implant
US20070226986A1 (en) 2006-02-15 2007-10-04 Ilwhan Park Arthroplasty devices and related methods
US20070233269A1 (en) 2001-05-25 2007-10-04 Conformis, Inc. Interpositional Joint Implant
US20070233141A1 (en) 2006-02-15 2007-10-04 Ilwhan Park Arthroplasty devices and related methods
US20080114370A1 (en) 2006-06-09 2008-05-15 Biomet Manufacturing Corp. Patient-Specific Alignment Guide For Multiple Incisions
US20080147072A1 (en) 2006-12-18 2008-06-19 Ilwhan Park Arthroplasty devices and related methods
US20080161815A1 (en) 2006-02-27 2008-07-03 Biomet Manufacturing Corp. Patient Specific Knee Alignment Guide And Associated Method
US20080195216A1 (en) 2001-05-25 2008-08-14 Conformis, Inc. Implant Device and Method for Manufacture
WO2008112996A1 (en) 2007-03-14 2008-09-18 Conformis, Inc. Surgical tools for arthroplasty
US20080243127A1 (en) 2001-05-25 2008-10-02 Conformis, Inc. Surgical Tools for Arthroplasty
US20080275452A1 (en) 2001-05-25 2008-11-06 Conformis, Inc. Surgical Cutting Guide
US20080287954A1 (en) 2007-05-14 2008-11-20 Queen's University At Kingston Patient-specific surgical guidance tool and method of use
US20090024131A1 (en) 2006-02-27 2009-01-22 Biomet Manufacturing Corp. Patient specific guides
US7510557B1 (en) 2000-01-14 2009-03-31 Bonutti Research Inc. Cutting guide
US20090088754A1 (en) 2007-09-30 2009-04-02 Chris Aker Customized Patient-Specific Multi-Cutting Blocks
US20090110498A1 (en) 2007-10-25 2009-04-30 Ilwhan Park Arthroplasty systems and devices, and related methods
US20090131941A1 (en) 2002-05-15 2009-05-21 Ilwhan Park Total joint arthroplasty system
US20090138020A1 (en) 2007-11-27 2009-05-28 Otismed Corporation Generating mri images usable for the creation of 3d bone models employed to make customized arthroplasty jigs
US20090157083A1 (en) 2007-12-18 2009-06-18 Ilwhan Park System and method for manufacturing arthroplasty jigs
US20090222014A1 (en) 2001-05-25 2009-09-03 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US20090222103A1 (en) 2001-05-25 2009-09-03 Conformis, Inc. Articular Implants Providing Lower Adjacent Cartilage Wear
US20090222016A1 (en) 2008-02-29 2009-09-03 Otismed Corporation Total hip replacement surgical guide tool
US20090228113A1 (en) 2008-03-05 2009-09-10 Comformis, Inc. Edge-Matched Articular Implant
US20090226068A1 (en) 2008-03-05 2009-09-10 Conformis, Inc. Implants for Altering Wear Patterns of Articular Surfaces
WO2009111639A1 (en) 2008-03-05 2009-09-11 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
US20090254093A1 (en) 2006-06-09 2009-10-08 Biomet Manufacturing Corp. Patient-Specific Alignment Guide
US20090270868A1 (en) 2008-04-29 2009-10-29 Otismed Corporation Generation of a computerized bone model representative of a pre-degenerated state and useable in the design and manufacture of arthroplasty devices
US20090276045A1 (en) 2001-05-25 2009-11-05 Conformis, Inc. Devices and Methods for Treatment of Facet and Other Joints
US20100023015A1 (en) 2008-07-23 2010-01-28 Otismed Corporation System and method for manufacturing arthroplasty jigs having improved mating accuracy
US20100042105A1 (en) 2007-12-18 2010-02-18 Otismed Corporation Arthroplasty system and related methods
US20100049195A1 (en) 2007-12-18 2010-02-25 Otismed Corporation Arthroplasty system and related methods
US20100082035A1 (en) 2008-09-30 2010-04-01 Ryan Keefer Customized patient-specific acetabular orthopaedic surgical instrument and method of use and fabrication
US20100087829A1 (en) 2006-02-27 2010-04-08 Biomet Manufacturing Corp. Patient Specific Alignment Guide With Cutting Surface and Laser Indicator
US20100152741A1 (en) 2008-12-16 2010-06-17 Otismed Corporation Unicompartmental customized arthroplasty cutting jigs and methods of making the same
US20100152782A1 (en) 2006-02-27 2010-06-17 Biomet Manufactring Corp. Patient Specific High Tibia Osteotomy
US20100185202A1 (en) 2009-01-16 2010-07-22 Lester Mark B Customized patient-specific patella resectioning guide
US20100191244A1 (en) 2007-03-23 2010-07-29 Derrick White Surgical templates
US20100211077A1 (en) 2002-08-23 2010-08-19 Pierre Couture Surgical universal positioning block and tool guide
US20100217270A1 (en) 2009-02-25 2010-08-26 Conformis, Inc. Integrated Production of Patient-Specific Implants and Instrumentation
US20100212138A1 (en) 2009-02-24 2010-08-26 Wright Medical Technology, Inc. Method For Forming A Patient Specific Surgical Guide Mount
WO2010099231A2 (en) 2009-02-24 2010-09-02 Conformis, Inc. Automated systems for manufacturing patient-specific orthopedic implants and instrumentation
WO2010099353A1 (en) 2009-02-25 2010-09-02 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
US20100256479A1 (en) 2007-12-18 2010-10-07 Otismed Corporation Preoperatively planning an arthroplasty procedure and generating a corresponding patient specific arthroplasty resection guide
US20100262150A1 (en) 2009-04-13 2010-10-14 George John Lian Custom radiographically designed cutting guides and instruments for use in total ankle replacement surgery
WO2010121147A1 (en) 2009-04-16 2010-10-21 Conformis, Inc. Patient-specific joint arthroplasty devices for ligament repair
US20100286700A1 (en) 2009-05-07 2010-11-11 Smith & Nephew, Inc. Patient specific alignment guide for a proximal femur
CA2765499A1 (en) 2009-06-24 2010-12-29 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
US20110015636A1 (en) 2006-02-27 2011-01-20 Biomet Manufacturing Corp. Patient-Specific Elbow Guides and Associated Methods
US20110015637A1 (en) 2009-07-17 2011-01-20 Materialise N.V. Surgical guiding tool, methods for manufacture and uses thereof
US20110015639A1 (en) 2006-02-27 2011-01-20 Biomet Manufacturing Corp. Femoral Acetabular Impingement Guide
US20110029116A1 (en) 2007-12-06 2011-02-03 Jason Sean Jordan Systems and methods for determining the mechanical axis of a femur
US20110029091A1 (en) 2009-02-25 2011-02-03 Conformis, Inc. Patient-Adapted and Improved Orthopedic Implants, Designs, and Related Tools
US20110040168A1 (en) 2002-09-16 2011-02-17 Conformis Imatx, Inc. System and Method for Predicting Future Fractures
US20110054478A1 (en) 2006-02-27 2011-03-03 Biomet Manufacturing Corp. Patient-Specific Shoulder Guide
CA2771573A1 (en) 2009-08-26 2011-03-10 Conformis, Inc. Patient-specific orthopedic implants and models
US20110060341A1 (en) 2009-09-10 2011-03-10 Laurent Angibaud Alignment guides for use in computer assisted orthopedic surgery to prepare a bone element for an implant
US20110071802A1 (en) 2009-02-25 2011-03-24 Ray Bojarski Patient-adapted and improved articular implants, designs and related guide tools
US20110071533A1 (en) 2006-02-27 2011-03-24 Biomet Manufacturing Corp. Patient-Specific Orthopedic Instruments
US20110071645A1 (en) 2009-02-25 2011-03-24 Ray Bojarski Patient-adapted and improved articular implants, designs and related guide tools
US20110087332A1 (en) 2001-05-25 2011-04-14 Ray Bojarski Patient-adapted and improved articular implants, designs and related guide tools
US20110093108A1 (en) 2008-02-27 2011-04-21 Depuy International Ltd Customised surgical apparatus
US20110092977A1 (en) 2008-03-03 2011-04-21 Smith & Nephew, Inc. Low profile patient specific cutting blocks for a knee joint
US20110106093A1 (en) 2009-10-29 2011-05-05 Zimmer, Inc. Patient-specific mill guide
CA2779283A1 (en) 2009-11-04 2011-05-12 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
US20110130761A1 (en) 2005-04-07 2011-06-02 Perception Raisonnement Action En Medecine Robotic guide assembly for use in computer-aided surgery
WO2011072235A2 (en) 2009-12-11 2011-06-16 Conformis, Inc. Patient-specific and patient-engineered orthopedic implants
WO2011075697A2 (en) 2009-12-18 2011-06-23 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
US7967868B2 (en) 2007-04-17 2011-06-28 Biomet Manufacturing Corp. Patient-modified implant and associated method
US20110160736A1 (en) 2006-02-27 2011-06-30 Biomet Manufacturing Corp. Patient-specific femoral guide
US20110160867A1 (en) 2006-02-27 2011-06-30 Biomet Manufacturing Corp. Patient-specific tools and implants
US20110166578A1 (en) 2006-02-27 2011-07-07 Biomet Manufacturing Corp. Alignment guides with patient-specific anchoring elements
US20110172672A1 (en) 2006-02-27 2011-07-14 Biomet Manufacturing Corp. Instrument with transparent portion for use with patient-specific alignment guide
AU2011203237A1 (en) 2003-11-25 2011-07-21 Conformis, Inc. Patient selectable knee joint arthroplasty devices
US20110184419A1 (en) 2006-02-27 2011-07-28 Biomet Manufacturing Corp. Patient-specific acetabular guides and associated instruments
US20110196377A1 (en) 2009-08-13 2011-08-11 Zimmer, Inc. Virtual implant placement in the or
US20110213376A1 (en) 2010-02-26 2011-09-01 Biomet Sports Medicine, Llc Patient-Specific Osteotomy Devices and Methods
US20110218545A1 (en) 2010-03-04 2011-09-08 Biomet Manufacturing Corp. Patient-specific computed tomography guides
US20110214279A1 (en) 2007-12-18 2011-09-08 Otismed Corporation Preoperatively planning an arthroplasty procedure and generating a corresponding patient specific arthroplasty resection guide
US20110224674A1 (en) 2006-02-27 2011-09-15 Biomet Manufacturing Corp. Patient-specific acetabular alignment guides
US20110245835A1 (en) 2007-06-25 2011-10-06 Depuy Orthopadie Gmbh Surgical Instrument
US20110266265A1 (en) 2007-02-14 2011-11-03 Conformis, Inc. Implant Device and Method for Manufacture
US20110275957A1 (en) 2010-05-06 2011-11-10 Sachin Bhandari Inertial Sensor Based Surgical Navigation System for Knee Replacement Surgery
US20110295378A1 (en) 2001-05-25 2011-12-01 Conformis, Inc. Patient-Adapted and Improved Orthopedic Implants, Designs and Related Tools
US8070752B2 (en) 2006-02-27 2011-12-06 Biomet Manufacturing Corp. Patient specific alignment guide and inter-operative adjustment
US20110313424A1 (en) 2010-06-18 2011-12-22 Howmedica Osteonics Corp. Patient-specific total hip arthroplasty
US8092465B2 (en) 2006-06-09 2012-01-10 Biomet Manufacturing Corp. Patient specific knee alignment guide and associated method
US20120010711A1 (en) 2010-06-11 2012-01-12 Antonyshyn Oleh Method of forming patient-specific implant
US20120041445A1 (en) 2010-08-12 2012-02-16 Roose Jeffrey R Customized patient-specific acetabular orthopaedic surgical instrument and method of use and fabrication
US20120041446A1 (en) 2006-02-06 2012-02-16 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools Incorporating Anatomical Relief
US8133234B2 (en) 2006-02-27 2012-03-13 Biomet Manufacturing Corp. Patient specific acetabular guide and method
US20120078259A1 (en) 2010-09-29 2012-03-29 Biomet Manufacturing Corp. Patient-specific guide for partial acetabular socket replacement
US20120078254A1 (en) 2010-09-29 2012-03-29 Depuy Products, Inc. Customized patient-specific computer controlled cutting system and method
US20120078258A1 (en) 2010-03-31 2012-03-29 Darrick Lo Shoulder arthroplasty instrumentation
US8160345B2 (en) 2008-04-30 2012-04-17 Otismed Corporation System and method for image segmentation in generating computer models of a joint to undergo arthroplasty
US8175683B2 (en) 2003-12-30 2012-05-08 Depuy Products, Inc. System and method of designing and manufacturing customized instrumentation for accurate implantation of prosthesis by utilizing computed tomography data
US20120116203A1 (en) 2010-11-10 2012-05-10 Wilfried Vancraen Additive manufacturing flow for the production of patient-specific devices comprising unique patient-specific identifiers
US20120116562A1 (en) 2010-06-11 2012-05-10 Smith & Nephew, Inc. Systems and methods Utilizing Patient-Matched Instruments
US20120123423A1 (en) 2010-11-11 2012-05-17 Zimmer, Inc. Patient-specific instruments for total hip arthroplasty
US20120130687A1 (en) 2008-09-19 2012-05-24 Smith & Nephew, Inc. Tuning Implants For Increased Performance
US20120130382A1 (en) 2010-09-07 2012-05-24 The Cleveland Clinic Foundation Positioning apparatus and method for a prosthetic implant
US20120141034A1 (en) 2010-10-29 2012-06-07 The Cleveland Clinic Foundation System of preoperative planning and provision of patient-specific surgical aids
US20120172884A1 (en) 2009-06-17 2012-07-05 University Of Bern Methods and devices for patient-specific acetabular component alignment in total hip arthroplasty
US20120209276A1 (en) 2009-08-13 2012-08-16 Biomet Manufacturing Corp. Device for the resection of bones, method for producing such a device, endoprosthesis suited for this purpose and method for producing such an endoprosthesis
US20120209394A1 (en) 1997-01-08 2012-08-16 Conformis, Inc. Patient-Adapted and Improved Articular Implants, Designs and Related Guide Tools
US20120226283A1 (en) 2006-02-27 2012-09-06 Biomet Manufacturing Corp. Patient-specific acetabular guides and associated instruments
US20120239045A1 (en) 2011-03-17 2012-09-20 Zimmer, Inc. Patient-specific instruments for total ankle arthroplasty
US20120245647A1 (en) 2009-11-17 2012-09-27 Manuela Kunz Patient-Specific Guide for Acetabular Cup Placement
US20120259420A1 (en) 2011-04-06 2012-10-11 Lashure Daniel E Proximal trial instrument for use during an orthopaedic surgical procedure to implant a revision hip prosthesis
US20120265208A1 (en) 2011-04-15 2012-10-18 Biomet Manufacturing Corp. Patient-specific numerically controlled instrument
US20120271366A1 (en) 2011-04-19 2012-10-25 Biomet Manufacturing Corp. Patient-specific fracture fixation instrumentation and method
US20120276509A1 (en) 2010-10-29 2012-11-01 The Cleveland Clinic Foundation System of preoperative planning and provision of patient-specific surgical aids
US20120277751A1 (en) 2011-04-29 2012-11-01 Biomet Manufacturing Corp. Patient-specific convertible guides
US20120296339A1 (en) 2011-05-19 2012-11-22 Iannotti Joseph P Apparatus and method for providing a reference indication to a patient tissue
WO2013020026A1 (en) 2011-08-03 2013-02-07 Conformis, Inc. Automated design, selection, manufacturing and implantation of patient-adapted and improved articular implants, designs and related guide tools
WO2013025814A1 (en) 2011-08-15 2013-02-21 Conformis, Inc. Revision systems, tools and methods for revising joint arthroplasty implants
WO2013056036A1 (en) 2011-10-14 2013-04-18 Conformis, Inc. Methods and systems for identification, assessment, modeling, and repair of anatomical disparities in joint replacement
US20130184713A1 (en) 2011-12-23 2013-07-18 Conformis, Inc. Anatomical Alignment Systems and Methods
WO2013119865A1 (en) 2012-02-07 2013-08-15 Conformis Inc Joint arthroplasty devices, systems, and methods
WO2013119790A1 (en) 2012-02-07 2013-08-15 Conformis, Inc. Tibial implant devices, systems, and methods
US20130211410A1 (en) 2012-02-07 2013-08-15 Conformis, Inc. Patella Resection Instrument Guide Having Optional Patient-Specific Features
US20130211531A1 (en) 2001-05-25 2013-08-15 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
WO2013131066A1 (en) 2012-03-02 2013-09-06 Conformis, Inc. Patient-adapted posterior stabilized knee implants, designs and related methods and tools
WO2013136302A1 (en) 2012-03-16 2013-09-19 Custom Med Orthopaedics Proprietary Limited A bone cutting guide and a bone cutting guide system
WO2013152341A1 (en) 2012-04-06 2013-10-10 Conformis, Inc. Advanced methods, techniques, devices, and systems for cruciate retaining knee implants
WO2013155501A1 (en) 2012-04-13 2013-10-17 Conformis, Inc. Patient adapted joint arthroplasty devices, surgical tools and methods of use
WO2013155500A1 (en) 2012-04-13 2013-10-17 Conformis, Inc. Devices and methods for additive manufacturing of implant components
US20130289570A1 (en) 2012-04-27 2013-10-31 Conformis, Inc. Tibial Template and Punch System, Tools and Methods for Preparing the Tibia
US20130296865A1 (en) * 2012-05-04 2013-11-07 Luke J. Aram Customized patient-specific orthopaedic pin guides
US20130296874A1 (en) 2012-04-18 2013-11-07 Conformis, Inc. Tibial guides, tools, and techniques for resecting the tibial plateau
US20130297031A1 (en) 2012-05-02 2013-11-07 Conformis, Inc. Patient specific instruments and related methods for joint replacement
US20130331850A1 (en) 2012-06-11 2013-12-12 Conformis, Inc. Devices, techniques and methods for assessing joint spacing, balancing soft tissues and obtaining desired kinematics for joint implant components
WO2014008444A1 (en) 2012-07-03 2014-01-09 Conformis, Inc. Devices, systems, and methods for impacting joint implant components
AU2014200073A1 (en) 2006-02-06 2014-01-23 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
WO2014035991A1 (en) 2012-08-27 2014-03-06 Conformis, Inc. Methods, devices and techniques for improved placement and fixation of shoulder implant components
WO2014047514A1 (en) 2012-09-21 2014-03-27 Conformis, Inc. Methods and systems for optimizing design and manufacture of implant components using solid freeform fabrication

Patent Citations (487)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4841975A (en) 1987-04-15 1989-06-27 Cemax, Inc. Preoperative planning of bone cuts and joint replacement using radiant energy scan imaging
US5098383A (en) 1990-02-08 1992-03-24 Artifax Ltd. Device for orienting appliances, prostheses, and instrumentation in medical procedures and methods of making same
US5179915A (en) 1992-01-06 1993-01-19 Osteonics Corporation Anatomically matching intramedullary alignment rod
US5490854A (en) 1992-02-20 1996-02-13 Synvasive Technology, Inc. Surgical cutting block and method of use
US5768134A (en) 1994-04-19 1998-06-16 Materialise, Naamloze Vennootschap Method for making a perfected medical model on the basis of digital image information of a part of the body
US5928240A (en) 1995-02-16 1999-07-27 Johnson; Lanny L. Apparatus for forming a centered bore for the femoral stem of a hip prosthesis
US5871018A (en) 1995-12-26 1999-02-16 Delp; Scott L. Computer-assisted surgical method
US20120209394A1 (en) 1997-01-08 2012-08-16 Conformis, Inc. Patient-Adapted and Improved Articular Implants, Designs and Related Guide Tools
US5916219A (en) 1997-02-10 1999-06-29 Matsuno; Shigeo Tibial plateau resection guide
US7510557B1 (en) 2000-01-14 2009-03-31 Bonutti Research Inc. Cutting guide
US20100228257A1 (en) 2000-01-14 2010-09-09 Bonutti Peter M Joint replacement component
US7806896B1 (en) 2000-01-14 2010-10-05 Marctec, Llc Knee arthroplasty method
US7806897B1 (en) 2000-01-14 2010-10-05 Marctec, Llc Knee arthroplasty and preservation of the quadriceps mechanism
US20120215226A1 (en) 2000-01-14 2012-08-23 Bonutti Peter M Methods for using a patient specific alignment device
US20130024000A1 (en) 2001-05-25 2013-01-24 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US8066708B2 (en) 2001-05-25 2011-11-29 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
US20100329530A1 (en) 2001-05-25 2010-12-30 Conformis, Inc. Patient Selectable Knee Joint Arthroplasty Devices
US20120197260A1 (en) 2001-05-25 2012-08-02 Conformis, Inc. Joint arthroplasty devices and surgical tools
US20120232669A1 (en) 2001-05-25 2012-09-13 Bojarski Raymond A Patient-adapted and improved articular implants, designs and related guide tools
US20120232670A1 (en) 2001-05-25 2012-09-13 Bojarski Raymond A Patient-adapted and improved orthopedic implants, designs and related tools
US20100303313A1 (en) 2001-05-25 2010-12-02 Conformis, Inc. Methods and Compositions for Articular Repair
US20100305907A1 (en) 2001-05-25 2010-12-02 Conformis, Inc. Patient Selectable Knee Arthroplasty Devices
US20040204760A1 (en) 2001-05-25 2004-10-14 Imaging Therapeutics, Inc. Patient selectable knee arthroplasty devices
US20040236424A1 (en) 2001-05-25 2004-11-25 Imaging Therapeutics, Inc. Patient selectable joint arthroplasty devices and surgical tools facilitating increased accuracy, speed and simplicity in performing total and partial joint arthroplasty
US20120071881A1 (en) 2001-05-25 2012-03-22 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
US20100305574A1 (en) 2001-05-25 2010-12-02 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US8105330B2 (en) 2001-05-25 2012-01-31 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
US8122582B2 (en) 2001-05-25 2012-02-28 Conformis, Inc. Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty
US20100305573A1 (en) 2001-05-25 2010-12-02 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US20100303324A1 (en) 2001-05-25 2010-12-02 Conformis, Inc. Methods and Compositions for Articular Repair
US8083745B2 (en) 2001-05-25 2011-12-27 Conformis, Inc. Surgical tools for arthroplasty
DE60239674D1 (en) 2001-05-25 2011-05-19 Conformis Inc Methods and compositions for repair of the surface of joints
AU2007202573A1 (en) 2001-05-25 2007-06-28 Conformis, Inc. Methods and compositions for articular resurfacing
US20100305708A1 (en) 2001-05-25 2010-12-02 Conformis, Inc. Patient Selectable Knee Joint Arthroplasty Devices
US20120232671A1 (en) 2001-05-25 2012-09-13 Bojarski Raymond A Patient-adapted and improved articular implants, designs and related guide tools
US20100281678A1 (en) 2001-05-25 2010-11-11 Conformis, Inc. Surgical Tools Facilitating Increased Accuracy, Speed and Simplicity in Performing Joint Arthroplasty
US20120191205A1 (en) 2001-05-25 2012-07-26 Bojarski Raymond A Patient-adapted and improved articular implants, designs and related guide tools
US20100274534A1 (en) 2001-05-25 2010-10-28 Conformis, Inc. Automated Systems for Manufacturing Patient-Specific Orthopedic Implants and Instrumentation
US20120071882A1 (en) 2001-05-25 2012-03-22 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
US20120245699A1 (en) 2001-05-25 2012-09-27 Conformis, Inc. Joint arthroplasty devices
US20050234461A1 (en) 2001-05-25 2005-10-20 Burdulis Albert G Jr Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty
US20050267584A1 (en) 2001-05-25 2005-12-01 Burdulis Albert G Jr Patient selectable knee joint arthroplasty devices
US20110029093A1 (en) 2001-05-25 2011-02-03 Ray Bojarski Patient-adapted and improved articular implants, designs and related guide tools
US20120197408A1 (en) 2001-05-25 2012-08-02 Conformis, Inc. Joint Arthroplasty Devices
US7981158B2 (en) 2001-05-25 2011-07-19 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
EP1389980A2 (en) 2001-05-25 2004-02-25 Imaging Therapeutics Methods and compositions for articular resurfacing
US20120066892A1 (en) 2001-05-25 2012-03-22 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
US20120289966A1 (en) 2001-05-25 2012-11-15 Conformis, Inc. Joint arthroplasty devices and surgical tools
US20120296337A1 (en) 2001-05-25 2012-11-22 Conformis, Inc. Joint arthroplasty devices and surgical tools
US20120191420A1 (en) 2001-05-25 2012-07-26 Bojarski Raymond A Patient-adapted and improved articular implants, designs and related guide tools
US20120072185A1 (en) 2001-05-25 2012-03-22 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
US20120071883A1 (en) 2001-05-25 2012-03-22 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
US20110087332A1 (en) 2001-05-25 2011-04-14 Ray Bojarski Patient-adapted and improved articular implants, designs and related guide tools
US8337501B2 (en) 2001-05-25 2012-12-25 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
US20120101503A1 (en) 2001-05-25 2012-04-26 Conformis, Inc. Surgical Tools for Arthroplasty
US20110295329A1 (en) 2001-05-25 2011-12-01 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
AU2002310193B2 (en) 2001-05-25 2007-03-29 Conformis, Inc. Methods and compositions for articular resurfacing
US8337507B2 (en) 2001-05-25 2012-12-25 Conformis, Inc. Methods and compositions for articular repair
US20110071581A1 (en) 2001-05-25 2011-03-24 Conformis, Inc. Surgical Tools for Arthroplasty
US20070083266A1 (en) 2001-05-25 2007-04-12 Vertegen, Inc. Devices and methods for treating facet joints, uncovertebral joints, costovertebral joints and other joints
US20030216669A1 (en) 2001-05-25 2003-11-20 Imaging Therapeutics, Inc. Methods and compositions for articular repair
US20070100462A1 (en) 2001-05-25 2007-05-03 Conformis, Inc Joint Arthroplasty Devices
US20140074441A1 (en) 2001-05-25 2014-03-13 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
US20110295378A1 (en) 2001-05-25 2011-12-01 Conformis, Inc. Patient-Adapted and Improved Orthopedic Implants, Designs and Related Tools
US20120143197A1 (en) 2001-05-25 2012-06-07 Conformis, Inc. Surgical Tools for Arthroplasty
US20070156171A1 (en) 2001-05-25 2007-07-05 Conformis, Inc. Implant Grasper
US20140066936A1 (en) 2001-05-25 2014-03-06 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
US20100174376A1 (en) 2001-05-25 2010-07-08 Conformis, Inc. Joint Arthroplasty Devices Formed In Situ
US20140066935A1 (en) 2001-05-25 2014-03-06 Conformis, Inc. Joint Arthroplasty Devices and Surgical Tools
US20140058396A1 (en) 2001-05-25 2014-02-27 Conformis, Inc. Joint Arthroplasty Devices and Surgical Tools
US20140058397A1 (en) 2001-05-25 2014-02-27 Conformis, Inc. Joint Arthroplasty Devices and Surgical Tools
US20070198022A1 (en) 2001-05-25 2007-08-23 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US20110066193A1 (en) 2001-05-25 2011-03-17 Conformis, Inc. Surgical Tools for Arthroplasty
US8657827B2 (en) 2001-05-25 2014-02-25 Conformis, Inc. Surgical tools for arthroplasty
US20140039631A1 (en) 2001-05-25 2014-02-06 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
US8641716B2 (en) 2001-05-25 2014-02-04 Conformis, Inc. Joint arthroplasty devices and surgical tools
US20140029814A1 (en) 2001-05-25 2014-01-30 Conformis, Inc. Patient Selectable Knee Arthroplasty Devices
US20070233269A1 (en) 2001-05-25 2007-10-04 Conformis, Inc. Interpositional Joint Implant
US20140031826A1 (en) 2001-05-25 2014-01-30 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US20070250169A1 (en) 2001-05-25 2007-10-25 Philipp Lang Joint arthroplasty devices formed in situ
US20100168754A1 (en) 2001-05-25 2010-07-01 Conformis, Inc. Joint Arthroplasty Devices and Surgical Tools
US20120158001A1 (en) 2001-05-25 2012-06-21 Conformis, Inc. Surgical Tools Facilitating Increased Accuracy, Speed and Simplicity in Performing Joint Arthroplasty
US20100160917A1 (en) 2001-05-25 2010-06-24 Conformis, Inc. Joint Arthroplasty Devices and Surgical Tools
US8343218B2 (en) 2001-05-25 2013-01-01 Conformis, Inc. Methods and compositions for articular repair
HK1059882A1 (en) 2001-05-25 2011-08-26 Conformis Inc Methods and compositions for articular resurfacing
US20140005792A1 (en) 2001-05-25 2014-01-02 Conformis, Inc. Methods and compositions for articular resurfacing
US8617172B2 (en) 2001-05-25 2013-12-31 Conformis, Inc. Joint arthroplasty devices and surgical tools
US8617242B2 (en) 2001-05-25 2013-12-31 Conformis, Inc. Implant device and method for manufacture
US20080195216A1 (en) 2001-05-25 2008-08-14 Conformis, Inc. Implant Device and Method for Manufacture
US8585708B2 (en) 2001-05-25 2013-11-19 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
US8568479B2 (en) 2001-05-25 2013-10-29 Conformis, Inc. Joint arthroplasty devices and surgical tools
US20080243127A1 (en) 2001-05-25 2008-10-02 Conformis, Inc. Surgical Tools for Arthroplasty
US8568480B2 (en) 2001-05-25 2013-10-29 Conformis, Inc. Joint arthroplasty devices and surgical tools
US20080275452A1 (en) 2001-05-25 2008-11-06 Conformis, Inc. Surgical Cutting Guide
US20080281329A1 (en) 2001-05-25 2008-11-13 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US20080281426A1 (en) 2001-05-25 2008-11-13 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US20080281328A1 (en) 2001-05-25 2008-11-13 Conformis, Inc. Surgical Tools for Arthroplasty
US8562611B2 (en) 2001-05-25 2013-10-22 Conformis, Inc. Joint arthroplasty devices and surgical tools
US8562618B2 (en) 2001-05-25 2013-10-22 Conformis, Inc. Joint arthroplasty devices and surgical tools
US7468075B2 (en) 2001-05-25 2008-12-23 Conformis, Inc. Methods and compositions for articular repair
US8561278B2 (en) 2001-05-25 2013-10-22 Conformis, Inc. Joint arthroplasty devices and surgical tools
US8556906B2 (en) 2001-05-25 2013-10-15 Conformis, Inc. Joint arthroplasty devices and surgical tools
US8556971B2 (en) 2001-05-25 2013-10-15 Conformis, Inc. Joint arthroplasty devices formed in situ
US20030055502A1 (en) 2001-05-25 2003-03-20 Philipp Lang Methods and compositions for articular resurfacing
US8556907B2 (en) 2001-05-25 2013-10-15 Conformis, Inc. Joint arthroplasty devices and surgical tools
US8556983B2 (en) 2001-05-25 2013-10-15 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
US8551099B2 (en) 2001-05-25 2013-10-08 Conformis, Inc. Surgical tools for arthroplasty
US8551103B2 (en) 2001-05-25 2013-10-08 Conformis, Inc. Joint arthroplasty devices and surgical tools
US8551169B2 (en) 2001-05-25 2013-10-08 Conformis, Inc. Joint arthroplasty devices and surgical tools
US8551102B2 (en) 2001-05-25 2013-10-08 Conformis, Inc. Joint arthroplasty devices and surgical tools
US8545569B2 (en) 2001-05-25 2013-10-01 Conformis, Inc. Patient selectable knee arthroplasty devices
US20130253522A1 (en) 2001-05-25 2013-09-26 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US20130245803A1 (en) 2001-05-25 2013-09-19 Conformis, Inc. Implant device and method for manufacture
US20130018379A1 (en) 2001-05-25 2013-01-17 Conformis, Inc. Joint arthroplasty devices and surgical tools
US8529630B2 (en) 2001-05-25 2013-09-10 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
US20130211531A1 (en) 2001-05-25 2013-08-15 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
US7534263B2 (en) 2001-05-25 2009-05-19 Conformis, Inc. Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty
US20130211409A1 (en) 2001-05-25 2013-08-15 Conformis, Inc. Surgical Tools Facilitating Increased Accuracy, Speed and Simplicity in Performing Joint Arthroplasty
US7717956B2 (en) 2001-05-25 2010-05-18 Conformis, Inc. Joint arthroplasty devices formed in situ
US8062302B2 (en) 2001-05-25 2011-11-22 Conformis, Inc. Surgical tools for arthroplasty
US20130197870A1 (en) 2001-05-25 2013-08-01 Conformis, Inc. Automated Systems for Manufacturing Patient-Specific Orthopedic Implants and Instrumentation
US8480754B2 (en) 2001-05-25 2013-07-09 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
CN100502808C (en) 2001-05-25 2009-06-24 肯弗默斯股份有限公司 Compositions for articular resurfacing
US20090222014A1 (en) 2001-05-25 2009-09-03 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US20090222103A1 (en) 2001-05-25 2009-09-03 Conformis, Inc. Articular Implants Providing Lower Adjacent Cartilage Wear
US8460304B2 (en) 2001-05-25 2013-06-11 Conformis, Inc. Joint arthroplasty devices and surgical tools
US20130123792A1 (en) 2001-05-25 2013-05-16 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US20120151730A1 (en) 2001-05-25 2012-06-21 Conformis, Inc. Joint arthroplasty devices and surgical tools
US8439926B2 (en) 2001-05-25 2013-05-14 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
US20130110471A1 (en) 2001-05-25 2013-05-02 Conformis, Inc. Methods and Compositions for Articular Repair
US20130103363A1 (en) 2001-05-25 2013-04-25 Conformis, Inc. Methods and Compositions for Articular Repair
US20130096562A1 (en) 2001-05-25 2013-04-18 Conformis, Inc. Joint arthroplasty devices and surgical tools
US20130081247A1 (en) 2001-05-25 2013-04-04 Conformis, Inc. Joint arthroplasty devices and surgical tools
US20130079781A1 (en) 2001-05-25 2013-03-28 Conformis, Inc. Joint arthroplasty devices and surgical tools
US20130079876A1 (en) 2001-05-25 2013-03-28 Conformis, Inc. Joint arthroplasty devices and surgical tools
US20090276045A1 (en) 2001-05-25 2009-11-05 Conformis, Inc. Devices and Methods for Treatment of Facet and Other Joints
US20130018464A1 (en) 2001-05-25 2013-01-17 Conformis, Inc. Joint arthroplasty devices and surgical tools
US7618451B2 (en) 2001-05-25 2009-11-17 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools facilitating increased accuracy, speed and simplicity in performing total and partial joint arthroplasty
US8377129B2 (en) 2001-05-25 2013-02-19 Conformis, Inc. Joint arthroplasty devices and surgical tools
US8366771B2 (en) 2001-05-25 2013-02-05 Conformis, Inc. Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty
US20130030419A1 (en) 2001-05-25 2013-01-31 Conformis, Inc. Joint arthroplasty devices and surgical tools
US20090306676A1 (en) 2001-05-25 2009-12-10 Conformis, Inc. Methods and compositions for articular repair
US20130018380A1 (en) 2001-05-25 2013-01-17 Conformis, Inc. Joint arthroplasty devices and surgical tools
US20090307893A1 (en) 2001-05-25 2009-12-17 Conformis, Inc. Surgical Tools Facilitating Increased Accuracy, Speed and Simplicity in Performing Joint Arthroplasty
US20090312805A1 (en) 2001-05-25 2009-12-17 Conformis, Inc. Methods and compositions for articular repair
US20130030441A1 (en) 2001-05-25 2013-01-31 Conformis, Inc. Joint arthroplasty devices and surgical tools
US20130023884A1 (en) 2001-05-25 2013-01-24 Conformis, Inc. Joint arthroplasty devices and surgical tools
US8234097B2 (en) 2001-05-25 2012-07-31 Conformis, Inc. Automated systems for manufacturing patient-specific orthopedic implants and instrumentation
US20090131941A1 (en) 2002-05-15 2009-05-21 Ilwhan Park Total joint arthroplasty system
US20100211077A1 (en) 2002-08-23 2010-08-19 Pierre Couture Surgical universal positioning block and tool guide
US20110040168A1 (en) 2002-09-16 2011-02-17 Conformis Imatx, Inc. System and Method for Predicting Future Fractures
CA2501041A1 (en) 2002-10-07 2004-04-22 Conformis, Inc. Minimally invasive joint implant with 3-dimensional geometry matching the articular surfaces
TWI231755B (en) 2002-10-07 2005-05-01 Conformis Inc An interpositional articular implant and the method for making the same
HK1072710A1 (en) 2002-10-07 2011-08-12 Conformis Inc Minimally invasive joint implant with 3-dimensional geometry matching the articular surfaces
US20040138754A1 (en) 2002-10-07 2004-07-15 Imaging Therapeutics, Inc. Minimally invasive joint implant with 3-Dimensional geometry matching the articular surfaces
CN1728976A (en) 2002-10-07 2006-02-01 康复米斯公司 Minimally invasive joint implant with 3-dimensional geometry matching the articular surfaces
US20040133276A1 (en) 2002-10-07 2004-07-08 Imaging Therapeutics, Inc. Minimally invasive joint implant with 3-Dimensional geometry matching the articular surfaces
US20110066245A1 (en) 2002-10-07 2011-03-17 Conformis, Inc. Minimally Invasive Joint Implant with 3-Dimensional Geometry Matching the Articular Surfaces
DE60336002D1 (en) 2002-10-07 2011-03-24 Conformis Inc Minimally invasive joint implant with the joint surfaces adapted three-dimensional geometry
EP1555962A1 (en) 2002-10-07 2005-07-27 Conformis, Inc. Minimally invasive joint implant with 3-dimensional geometry matching the articular surfaces
US7799077B2 (en) 2002-10-07 2010-09-21 Conformis, Inc. Minimally invasive joint implant with 3-dimensional geometry matching the articular surfaces
US8077950B2 (en) 2002-11-07 2011-12-13 Conformis, Inc. Methods for determining meniscal size and shape and for devising treatment
US20040147927A1 (en) 2002-11-07 2004-07-29 Imaging Therapeutics, Inc. Methods for determining meniscal size and shape and for devising treatment
US20040153079A1 (en) 2002-11-07 2004-08-05 Imaging Therapeutics, Inc. Methods for determining meniscal size and shape and for devising treatment
US20100303317A1 (en) 2002-11-07 2010-12-02 Conformis, Inc. Methods for Determining Meniscal Size and Shape and for Devising Treatment
US20120093377A1 (en) 2002-11-07 2012-04-19 Conformis, Inc. Methods for determining meniscal size and shape and for devising treatment
US8634617B2 (en) 2002-11-07 2014-01-21 Conformis, Inc. Methods for determining meniscal size and shape and for devising treatment
CA2505371A1 (en) 2002-11-07 2004-05-27 Conformis, Inc. Methods for determining meniscal size and shape and for devising treatment
US7796791B2 (en) 2002-11-07 2010-09-14 Conformis, Inc. Methods for determining meniscal size and shape and for devising treatment
EP1558181A1 (en) 2002-11-07 2005-08-03 Conformis, Inc. Methods for determing meniscal size and shape and for devising treatment
JP2011224384A (en) 2002-11-27 2011-11-10 Conformis Inc Patient selectable joint arthroplasty device and surgical tool facilitating increased accuracy, speed and simplicity in performing total and partial joint arthroplasty
CN102125448A (en) 2002-11-27 2011-07-20 康复米斯公司 Patient-specific surgical tools
TWI330075B (en) 2002-11-27 2010-09-11 Conformis Inc Patient selectable joint arthroplasty devices and surgical tools facilitating increased accuracy, speed and simplicity in performing total and partial joint arthroplasty and methods of designing an articular implant and evaluating the fit of an articula
EP2292188A2 (en) 2002-11-27 2011-03-09 Conformis, Inc. Patient selectable surgical tools
JP2012187415A (en) 2002-11-27 2012-10-04 Conformis Inc Patient selectable joint arthroplasty device and surgical tool facilitating increased accuracy, speed and simplicity in performing total and partial joint arthroplasty
EP1575460A2 (en) 2002-11-27 2005-09-21 Conformis, Inc. Patient selectable total and partial joint arthroplasty devices and surgical tools
WO2004049981A2 (en) 2002-11-27 2004-06-17 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools facilitating increased accuracy, speed and simplicity in performing total and partial joint arthroplasty
KR20050084024A (en) 2002-11-27 2005-08-26 콘포미스 인코퍼레이티드 Patient selectable joint arthroplasty devices and surgical tools facilitating increased accuracy, speed and simplicity in performing total and partial joint arthroplasty
JP2006510403A (en) 2002-11-27 2006-03-30 コンフォーミス・インコーポレイテッドConforMIS, Inc. Total or partial arthroplasty in accuracy, speed and surgical tools and selectable arthroplasty device by the patient to facilitate the increase in simplicity
JP5053515B2 (en) 2002-11-27 2012-10-17 コンフォーミス・インコーポレイテッドConforMIS, Inc. Total or partial arthroplasty in accuracy, speed and surgical tools and selectable arthroplasty device by the patient to facilitate the increase in simplicity
CA2505419A1 (en) 2002-11-27 2004-06-17 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools facilitating increased accuracy, speed and simplicity in performing total and partial joint arthroplasty
AU2010201200A1 (en) 2002-11-27 2010-04-15 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools facilitating increased accuracy, speed and simplicity in performing total and partial joint arthroplasty
EP2292189A2 (en) 2002-11-27 2011-03-09 Conformis, Inc. Patient selectable surgical tools
CN1729483A (en) 2002-11-27 2006-02-01 康复米斯公司 Patient selectable joint arthroplasty devices and surgical tools facilitating increased accuracy, speed and simplicity in performing total and partial joint arthroplasty
TW200509870A (en) 2002-11-27 2005-03-16 Conformis Inc Patient selectable joint arthroplasty devices and surgical tools facilitating increased accuracy, speed and simplicity in performing total and partial joint arthroplasty
JP2014000425A (en) 2002-11-27 2014-01-09 Conformis Inc Arthroplasty device and operation tool that facilitate increase in accuracy, speed and simplicity in overall or partial arthroplasty and that are selective by patient
US20040204644A1 (en) 2002-12-04 2004-10-14 Imaging Therapeutics, Inc. Fusion of multiple imaging planes for isotropic imaging in MRI and quantitative image analysis using isotropic or near-isotropic imaging
WO2004051301A2 (en) 2002-12-04 2004-06-17 Conformis, Inc. Fusion of multiple imaging planes for isotropic imaging in mri and quantitative image analysis using isotropic or near-isotropic imaging
US20100054572A1 (en) 2002-12-04 2010-03-04 Conformis, Inc. Fusion of Multiple Imaging Planes for Isotropic Imaging in MRI and Quantitative Image Analysis using Isotropic or Near-isotropic Imaging
US8638998B2 (en) 2002-12-04 2014-01-28 Conformis, Inc. Fusion of multiple imaging planes for isotropic imaging in MRI and quantitative image analysis using isotropic or near-isotropic imaging
US8094900B2 (en) 2002-12-04 2012-01-10 Conformis, Inc. Fusion of multiple imaging planes for isotropic imaging in MRI and quantitative image analysis using isotropic or near-isotropic imaging
CA2506849A1 (en) 2002-12-04 2004-06-17 Konstantinos Tsougarakis Fusion of multiple imaging planes for isotropic imaging in mri and quantitative image analysis using isotropic or near-isotropic imaging
KR20050072500A (en) 2002-12-04 2005-07-11 콘포미스 인코퍼레이티드 Fusion of multiple imaging planes for isotropic imaging in mri and quantitative image analysis using isotropic or near-isotropic imaging
EP1567985A2 (en) 2002-12-04 2005-08-31 Conformis, Inc. Fusion of multiple imaging planes for isotropic imaging in mri and quantitative image analysis using isotropic or near-isotropic imaging
CN1729484A (en) 2002-12-04 2006-02-01 康复米斯公司 Fusion of multiple imaging planes for isotropic imaging in MRI and quantitative image analysis using isotropic or near-isotropic imaging
US7634119B2 (en) 2002-12-04 2009-12-15 Conformis, Inc. Fusion of multiple imaging planes for isotropic imaging in MRI and quantitative image analysis using isotropic or near-isotropic imaging
US20120201440A1 (en) 2002-12-04 2012-08-09 Conformis, Inc. Fusion of Multiple Imaging Planes for Isotropic Imaging in MRI and Quantitative Image Analysis using Isotropic or Near-isotropic Imaging
AU2004293091A1 (en) 2003-11-25 2005-06-09 Conformis, Inc. Joint arthroplasty devices formed in situ
JP2012176318A (en) 2003-11-25 2012-09-13 Conformis Inc Prosthetic apparatus unique to each patient, system with the prosthetic apparatus, manufacturing method thereof, and joint repair system
AU2012216829A1 (en) 2003-11-25 2012-10-04 Conformis, Inc. Patient selectable knee joint arthroplasty devices
JP5074036B2 (en) 2003-11-25 2012-11-14 コンフォーミス・インコーポレイテッドConforMIS, Inc. Specific implant for each patient for the distal femur transplant
CN102805677A (en) 2003-11-25 2012-12-05 康复米斯公司 Patient selectable knee joint arthroplasty devices
AU2011203237A1 (en) 2003-11-25 2011-07-21 Conformis, Inc. Patient selectable knee joint arthroplasty devices
US20110213430A1 (en) 2003-11-25 2011-09-01 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US20110213427A1 (en) 2003-11-25 2011-09-01 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US20110213374A1 (en) 2003-11-25 2011-09-01 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US20110230888A1 (en) 2003-11-25 2011-09-22 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
JP2007514470A (en) 2003-11-25 2007-06-07 コンフォーミス・インコーポレイテッドConforMIS, Inc. Selectable knee arthroplasty device for each patient
US20110213368A1 (en) 2003-11-25 2011-09-01 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US20110213373A1 (en) 2003-11-25 2011-09-01 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
CN1913844A (en) 2003-11-25 2007-02-14 康复米斯公司 Patient selectable knee joint arthroplasty devices
EP1686930A1 (en) 2003-11-25 2006-08-09 Conformis, Inc. Joint arthroplasty devices formed in situ
EP1686931A1 (en) 2003-11-25 2006-08-09 Conformis, Inc. Patient selectable knee joint arthroplasty devices
US20110213377A1 (en) 2003-11-25 2011-09-01 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
HK1087324A1 (en) 2003-11-25 2011-11-18 Conformis Inc Joint arthroplasty devices formed in situ
US20110213431A1 (en) 2003-11-25 2011-09-01 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US20110213428A1 (en) 2003-11-25 2011-09-01 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US20110213429A1 (en) 2003-11-25 2011-09-01 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US20110238073A1 (en) 2003-11-25 2011-09-29 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US20110218539A1 (en) 2003-11-25 2011-09-08 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
CA2546965A1 (en) 2003-11-25 2005-06-09 Conformis, Inc. Patient selectable knee joint arthroplasty devices
AU2004293104A1 (en) 2003-11-25 2005-06-09 Conformis Inc Patient selectable knee joint arthroplasty devices
DE602004032166D1 (en) 2003-11-25 2011-05-19 Conformis Inc In situ molded gelenkarthroplastie devices
WO2005051239A1 (en) 2003-11-25 2005-06-09 Conformis, Inc. Joint arthroplasty devices formed in situ
WO2005051240A1 (en) 2003-11-25 2005-06-09 Conformis, Inc. Patient selectable knee joint arthroplasty devices
CA2804883A1 (en) 2003-11-25 2005-06-09 Conformis, Inc. Patient selectable knee joint arthroplasty devices
CA2546958A1 (en) 2003-11-25 2005-06-09 Conformis, Inc. Joint arthroplasty devices formed in situ
US20120029520A1 (en) 2003-11-25 2012-02-02 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
EP2335654A1 (en) 2003-11-25 2011-06-22 Conformis, Inc. Patient selectable knee joint arthoplasty devices
US20110218584A1 (en) 2003-11-25 2011-09-08 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US8175683B2 (en) 2003-12-30 2012-05-08 Depuy Products, Inc. System and method of designing and manufacturing customized instrumentation for accurate implantation of prosthesis by utilizing computed tomography data
US20110144760A1 (en) 2004-01-05 2011-06-16 Conformis, Inc. Patient-Specific and Patient-Engineered Orthopedic Implants
US20050203524A1 (en) 2004-03-04 2005-09-15 Penenberg Brad L. Bone preserving total hip arthroplasty using autograft
US20060111722A1 (en) 2004-11-19 2006-05-25 Hacene Bouadi Surgical cutting tool
US8529568B2 (en) 2004-11-19 2013-09-10 Conformis, Inc. Surgical cutting tool
US20100234849A1 (en) 2004-11-19 2010-09-16 Conformis, Inc. Surgical Cutting Tool
WO2006058057A2 (en) 2004-11-24 2006-06-01 Conformis, Inc. Patient selectable knee joint arthroplasty devices
AU2005309692A1 (en) 2004-11-24 2006-06-01 Conformis, Inc. Patient selectable knee joint arthroplasty devices
JP5198069B2 (en) 2004-11-24 2013-05-15 コンフォーミス・インコーポレイテッドConforMIS, Inc. Arthroplasty device of patient-selectable knee joint
CN101442960A (en) 2004-11-24 2009-05-27 肯弗默斯股份有限公司 Patient selectable knee joint arthroplasty devices
EP1814491A1 (en) 2004-11-24 2007-08-08 Conformis, Inc. Patient selectable knee joint arthroplasty devices
CA2590534A1 (en) 2004-11-24 2006-06-01 Conformis, Inc. Patient selectable knee joint arthroplasty devices
EP2324799A2 (en) 2004-11-24 2011-05-25 Conformis, Inc. Patient selectable knee joint arthroplasty devices
JP5148284B2 (en) 2004-12-02 2013-02-20 コンフォーミス・インコーポレイテッドConforMIS, Inc. Surgical brace to achieve accurate, quick and easy joint replacement
EP1833387A1 (en) 2004-12-02 2007-09-19 Conformis, Inc. Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty
HK1104776A1 (en) 2004-12-02 2011-11-18 Conformis Inc Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty
DE602005027391D1 (en) 2004-12-02 2011-05-19 Conformis Inc The surgical tool to increase the accuracy, speed and simplicity in the execution of gelenkarthroplastien
EP2316357A1 (en) 2004-12-02 2011-05-04 Conformis, Inc. Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty
CA2588907A1 (en) 2004-12-02 2006-06-08 Conformis, Inc. Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty
AU2005311558A1 (en) 2004-12-02 2006-06-08 Conformis, Inc. Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty
WO2006060795A1 (en) 2004-12-02 2006-06-08 Conformis, Inc. Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty
CN101111197A (en) 2004-12-02 2008-01-23 肯弗默斯股份有限公司 Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty
US20110130761A1 (en) 2005-04-07 2011-06-02 Perception Raisonnement Action En Medecine Robotic guide assembly for use in computer-aided surgery
JP2012091033A (en) 2005-09-30 2012-05-17 Conformis Inc Joint arthroplasty device
AU2006297137A1 (en) 2005-09-30 2007-04-12 Conformis Inc. Joint arthroplasty devices
CA2623834A1 (en) 2005-09-30 2007-04-12 Conformis, Inc. Joint arthroplasty devices
EP1928359A2 (en) 2005-09-30 2008-06-11 Conformis, Inc. Joint arthroplasty devices
WO2007041375A2 (en) 2005-09-30 2007-04-12 Conformis, Inc. Joint arthroplasty devices
CN101384230A (en) 2005-11-21 2009-03-11 福特真公司 Devices and methods for treating facet joints, uncovertebral joints, costovertebral joints and other joints
EP1951136A1 (en) 2005-11-23 2008-08-06 Conformis, Inc. Implant grasper
WO2007062103A1 (en) 2005-11-23 2007-05-31 Conformis, Inc. Implant grasper
US7357057B2 (en) 2006-01-06 2008-04-15 Tung-Lung Chiang Paper cutter
US20070157783A1 (en) 2006-01-06 2007-07-12 Tung-Lung Chiang Paper cutter
EP2649951A2 (en) 2006-02-06 2013-10-16 ConforMIS, Inc. Patient selectable joint arthroplasty devices and surgical tools
EP2671522A2 (en) 2006-02-06 2013-12-11 ConforMIS, Inc. Patient selectable joint arthroplasty devices and surgical tools
EP2710967A2 (en) 2006-02-06 2014-03-26 ConforMIS, Inc. Patient selectable joint arthroplasty devices and surgical tools
CN101420911B (en) 2006-02-06 2012-07-18 康复米斯公司 Patient selectable arthroplasty device and surjical tool
CN102599960A (en) 2006-02-06 2012-07-25 康复米斯公司 Patient selectable joint arthroplasty devices and surgical tools
EP1981409A2 (en) 2006-02-06 2008-10-22 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
WO2007092841A2 (en) 2006-02-06 2007-08-16 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
CA2641241A1 (en) 2006-02-06 2007-08-16 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
US8500740B2 (en) 2006-02-06 2013-08-06 Conformis, Inc. Patient-specific joint arthroplasty devices for ligament repair
US20130317511A1 (en) 2006-02-06 2013-11-28 Conformis, Inc. Patient-specific joint arthroplasty devices for ligament repair
TW200800123A (en) 2006-02-06 2008-01-01 Conformis Inc Patient selectable joint arthroplasty devices and surgical tools
AU2014200073A1 (en) 2006-02-06 2014-01-23 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
AU2007212033A1 (en) 2006-02-06 2007-08-16 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
EP2671521A2 (en) 2006-02-06 2013-12-11 ConforMIS, Inc. Patient selectable joint arthroplasty devices and surgical tools
US20110313423A1 (en) 2006-02-06 2011-12-22 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US20120041446A1 (en) 2006-02-06 2012-02-16 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools Incorporating Anatomical Relief
US20110319900A1 (en) 2006-02-06 2011-12-29 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US20110319897A1 (en) 2006-02-06 2011-12-29 Conformis, Inc. Patient Selectable Joint Arthroplasty Devices and Surgical Tools
US20100298894A1 (en) 2006-02-06 2010-11-25 Conformis, Inc. Patient-Specific Joint Arthroplasty Devices for Ligament Repair
EP2671520A2 (en) 2006-02-06 2013-12-11 ConforMIS, Inc. Patient selectable joint arthroplasty devices and surgical tools
US8623026B2 (en) 2006-02-06 2014-01-07 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools incorporating anatomical relief
US20070233141A1 (en) 2006-02-15 2007-10-04 Ilwhan Park Arthroplasty devices and related methods
US20070226986A1 (en) 2006-02-15 2007-10-04 Ilwhan Park Arthroplasty devices and related methods
US20110166578A1 (en) 2006-02-27 2011-07-07 Biomet Manufacturing Corp. Alignment guides with patient-specific anchoring elements
US20110015636A1 (en) 2006-02-27 2011-01-20 Biomet Manufacturing Corp. Patient-Specific Elbow Guides and Associated Methods
US20120226283A1 (en) 2006-02-27 2012-09-06 Biomet Manufacturing Corp. Patient-specific acetabular guides and associated instruments
US20110054478A1 (en) 2006-02-27 2011-03-03 Biomet Manufacturing Corp. Patient-Specific Shoulder Guide
US20110224674A1 (en) 2006-02-27 2011-09-15 Biomet Manufacturing Corp. Patient-specific acetabular alignment guides
US20110160736A1 (en) 2006-02-27 2011-06-30 Biomet Manufacturing Corp. Patient-specific femoral guide
US20090024131A1 (en) 2006-02-27 2009-01-22 Biomet Manufacturing Corp. Patient specific guides
US8241293B2 (en) 2006-02-27 2012-08-14 Biomet Manufacturing Corp. Patient specific high tibia osteotomy
US8133234B2 (en) 2006-02-27 2012-03-13 Biomet Manufacturing Corp. Patient specific acetabular guide and method
US8282646B2 (en) 2006-02-27 2012-10-09 Biomet Manufacturing Corp. Patient specific knee alignment guide and associated method
US20080161815A1 (en) 2006-02-27 2008-07-03 Biomet Manufacturing Corp. Patient Specific Knee Alignment Guide And Associated Method
US20110184419A1 (en) 2006-02-27 2011-07-28 Biomet Manufacturing Corp. Patient-specific acetabular guides and associated instruments
US20100152782A1 (en) 2006-02-27 2010-06-17 Biomet Manufactring Corp. Patient Specific High Tibia Osteotomy
US20100087829A1 (en) 2006-02-27 2010-04-08 Biomet Manufacturing Corp. Patient Specific Alignment Guide With Cutting Surface and Laser Indicator
US20110071533A1 (en) 2006-02-27 2011-03-24 Biomet Manufacturing Corp. Patient-Specific Orthopedic Instruments
US20110015639A1 (en) 2006-02-27 2011-01-20 Biomet Manufacturing Corp. Femoral Acetabular Impingement Guide
US20120109138A1 (en) 2006-02-27 2012-05-03 Biomet Manufacturing Corp. Patient-specific acetabular guide and method
US20130131681A1 (en) 2006-02-27 2013-05-23 Biomet Manufacturing Corporation Patient-Specific Elbow Guides And Associated Methods
US8070752B2 (en) 2006-02-27 2011-12-06 Biomet Manufacturing Corp. Patient specific alignment guide and inter-operative adjustment
US20110172672A1 (en) 2006-02-27 2011-07-14 Biomet Manufacturing Corp. Instrument with transparent portion for use with patient-specific alignment guide
US20110160867A1 (en) 2006-02-27 2011-06-30 Biomet Manufacturing Corp. Patient-specific tools and implants
AU2007226924A1 (en) 2006-03-21 2007-09-27 Conformis, Inc. Interpositional joint implant
WO2007109641A2 (en) 2006-03-21 2007-09-27 Conformis, Inc. Interpositional joint implant
EP1996121A2 (en) 2006-03-21 2008-12-03 Conformis, Inc. Interpositional joint implant
CA2646288A1 (en) 2006-03-21 2007-09-27 Conformis, Inc. Interpositional joint implant
US8092465B2 (en) 2006-06-09 2012-01-10 Biomet Manufacturing Corp. Patient specific knee alignment guide and associated method
US20080114370A1 (en) 2006-06-09 2008-05-15 Biomet Manufacturing Corp. Patient-Specific Alignment Guide For Multiple Incisions
US20090254093A1 (en) 2006-06-09 2009-10-08 Biomet Manufacturing Corp. Patient-Specific Alignment Guide
US20120065640A1 (en) 2006-06-09 2012-03-15 Biomet Manufacturing Corp. Patient-specific knee alignment guide and associated method
US8298237B2 (en) 2006-06-09 2012-10-30 Biomet Manufacturing Corp. Patient-specific alignment guide for multiple incisions
US20080147072A1 (en) 2006-12-18 2008-06-19 Ilwhan Park Arthroplasty devices and related methods
EP2591756A1 (en) 2007-02-14 2013-05-15 Conformis, Inc. Implant device and method for manufacture
EP2114312A2 (en) 2007-02-14 2009-11-11 Conformis, Inc. Implant device and method for manufacture
WO2008101090A2 (en) 2007-02-14 2008-08-21 Conformis, Inc. Implant device and method for manufacture
US20110266265A1 (en) 2007-02-14 2011-11-03 Conformis, Inc. Implant Device and Method for Manufacture
EP2124764A1 (en) 2007-03-14 2009-12-02 Conformis, Inc. Surgical tools for arthroplasty
WO2008112996A1 (en) 2007-03-14 2008-09-18 Conformis, Inc. Surgical tools for arthroplasty
US20100191244A1 (en) 2007-03-23 2010-07-29 Derrick White Surgical templates
US7967868B2 (en) 2007-04-17 2011-06-28 Biomet Manufacturing Corp. Patient-modified implant and associated method
US20080287954A1 (en) 2007-05-14 2008-11-20 Queen's University At Kingston Patient-specific surgical guidance tool and method of use
WO2008157412A2 (en) 2007-06-13 2008-12-24 Conformis, Inc. Surgical cutting guide
US20110245835A1 (en) 2007-06-25 2011-10-06 Depuy Orthopadie Gmbh Surgical Instrument
US20090088753A1 (en) 2007-09-30 2009-04-02 Aram Luke J Customized Patient-Specific Instrumentation for Use in Orthopaedic Surgical Procedures
US20090088758A1 (en) 2007-09-30 2009-04-02 Travis Bennett Orthopaedic Bone Saw and Method of Use Thereof
US20090088760A1 (en) 2007-09-30 2009-04-02 Aram Luke J Customized Patient-Specific Bone Cutting Instrumentation
US20090088755A1 (en) 2007-09-30 2009-04-02 Chris Aker Customized Patient-Specific Instrumentation for Use in Orthopaedic Surgical Procedures
US20090088763A1 (en) 2007-09-30 2009-04-02 Aram Luke J Customized Patient-Specific Bone Cutting Block with External Reference
US20090087276A1 (en) 2007-09-30 2009-04-02 Bryan Rose Apparatus and Method for Fabricating a Customized Patient-Specific Orthopaedic Instrument
US20090093816A1 (en) 2007-09-30 2009-04-09 Roose Jeffrey R System and Method for Fabricating a Customized Patient-Specific Surgical Instrument
US20090088759A1 (en) 2007-09-30 2009-04-02 Aram Luke J Customized Patient-Specific Instrumentation and Method for Performing a Bone Re-Cut
US20090099567A1 (en) 2007-09-30 2009-04-16 Eric Zajac Customized Patient-Specific Bone Cutting Blocks
US20090088754A1 (en) 2007-09-30 2009-04-02 Chris Aker Customized Patient-Specific Multi-Cutting Blocks
US20090131942A1 (en) 2007-09-30 2009-05-21 Chris Aker Femoral Tibial Customized Patient-Specific Orthopaedic Surgical Instrumentation
US20090088761A1 (en) 2007-09-30 2009-04-02 Roose Jeffrey R Patient-Customizable Device and System for Performing an Orthopaedic Surgical Procedure
US20090110498A1 (en) 2007-10-25 2009-04-30 Ilwhan Park Arthroplasty systems and devices, and related methods
US20090138020A1 (en) 2007-11-27 2009-05-28 Otismed Corporation Generating mri images usable for the creation of 3d bone models employed to make customized arthroplasty jigs
US20110029116A1 (en) 2007-12-06 2011-02-03 Jason Sean Jordan Systems and methods for determining the mechanical axis of a femur
US20110214279A1 (en) 2007-12-18 2011-09-08 Otismed Corporation Preoperatively planning an arthroplasty procedure and generating a corresponding patient specific arthroplasty resection guide
US20100049195A1 (en) 2007-12-18 2010-02-25 Otismed Corporation Arthroplasty system and related methods
US8221430B2 (en) 2007-12-18 2012-07-17 Otismed Corporation System and method for manufacturing arthroplasty jigs
US20100042105A1 (en) 2007-12-18 2010-02-18 Otismed Corporation Arthroplasty system and related methods
US20100256479A1 (en) 2007-12-18 2010-10-07 Otismed Corporation Preoperatively planning an arthroplasty procedure and generating a corresponding patient specific arthroplasty resection guide
US20090157083A1 (en) 2007-12-18 2009-06-18 Ilwhan Park System and method for manufacturing arthroplasty jigs
US20110093108A1 (en) 2008-02-27 2011-04-21 Depuy International Ltd Customised surgical apparatus
US20090222016A1 (en) 2008-02-29 2009-09-03 Otismed Corporation Total hip replacement surgical guide tool
US20110092977A1 (en) 2008-03-03 2011-04-21 Smith & Nephew, Inc. Low profile patient specific cutting blocks for a knee joint
EP2259753A1 (en) 2008-03-05 2010-12-15 Conformis, Inc. Edge-matched articular implant
AU2009221773A1 (en) 2008-03-05 2009-09-11 Conformis, Inc. Edge-matched articular implant
EP2265199A1 (en) 2008-03-05 2010-12-29 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
US8682052B2 (en) 2008-03-05 2014-03-25 Conformis, Inc. Implants for altering wear patterns of articular surfaces
WO2009111639A1 (en) 2008-03-05 2009-09-11 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
WO2009111626A2 (en) 2008-03-05 2009-09-11 Conformis, Inc. Implants for altering wear patterns of articular surfaces
US20090226068A1 (en) 2008-03-05 2009-09-10 Conformis, Inc. Implants for Altering Wear Patterns of Articular Surfaces
US20090228113A1 (en) 2008-03-05 2009-09-10 Comformis, Inc. Edge-Matched Articular Implant
CN102006841A (en) 2008-03-05 2011-04-06 肯弗默斯股份有限公司 Edge-matched articular implant
WO2009111656A1 (en) 2008-03-05 2009-09-11 Conformis, Inc. Edge-matched articular implant
CA2717760A1 (en) 2008-03-05 2009-09-11 Conformis, Inc. Edge-matched articular implant
US20090270868A1 (en) 2008-04-29 2009-10-29 Otismed Corporation Generation of a computerized bone model representative of a pre-degenerated state and useable in the design and manufacture of arthroplasty devices
US8160345B2 (en) 2008-04-30 2012-04-17 Otismed Corporation System and method for image segmentation in generating computer models of a joint to undergo arthroplasty
US20120192401A1 (en) 2008-04-30 2012-08-02 Otismed Corporation System and method for image segmentation in generating computer models of a joint to undergo arthroplasty
WO2009140294A1 (en) 2008-05-12 2009-11-19 Conformis, Inc. Devices and methods for treatment of facet and other joints
AU2009246474A1 (en) 2008-05-12 2009-11-19 Conformis, Inc. Devices and methods for treatment of facet and other joints
JP2011519713A (en) 2008-05-12 2011-07-14 コンフォーミス・インコーポレイテッドConforMIS, Inc. Devices and methods for the treatment of facet joints and other joints
EP2303193A1 (en) 2008-05-12 2011-04-06 Conformis, Inc. Devices and methods for treatment of facet and other joints
US20100023015A1 (en) 2008-07-23 2010-01-28 Otismed Corporation System and method for manufacturing arthroplasty jigs having improved mating accuracy
US20120130687A1 (en) 2008-09-19 2012-05-24 Smith & Nephew, Inc. Tuning Implants For Increased Performance
US20100082035A1 (en) 2008-09-30 2010-04-01 Ryan Keefer Customized patient-specific acetabular orthopaedic surgical instrument and method of use and fabrication
US20100152741A1 (en) 2008-12-16 2010-06-17 Otismed Corporation Unicompartmental customized arthroplasty cutting jigs and methods of making the same
US20100185202A1 (en) 2009-01-16 2010-07-22 Lester Mark B Customized patient-specific patella resectioning guide
EP2405865A2 (en) 2009-02-24 2012-01-18 Conformis, Inc. Automated systems for manufacturing patient-specific orthopedic implants and instrumentation
US20120221008A1 (en) 2009-02-24 2012-08-30 Wright Medical Technology, Inc. Patient specific surgical guide locator and mount
US20100212138A1 (en) 2009-02-24 2010-08-26 Wright Medical Technology, Inc. Method For Forming A Patient Specific Surgical Guide Mount
WO2010099231A2 (en) 2009-02-24 2010-09-02 Conformis, Inc. Automated systems for manufacturing patient-specific orthopedic implants and instrumentation
US20100217338A1 (en) 2009-02-24 2010-08-26 Wright Medical Technology, Inc. Patient Specific Surgical Guide Locator and Mount
US20110029091A1 (en) 2009-02-25 2011-02-03 Conformis, Inc. Patient-Adapted and Improved Orthopedic Implants, Designs, and Related Tools
EP2403434A1 (en) 2009-02-25 2012-01-11 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
US20100217270A1 (en) 2009-02-25 2010-08-26 Conformis, Inc. Integrated Production of Patient-Specific Implants and Instrumentation
AU2010217903A1 (en) 2009-02-25 2011-09-15 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
CN102405032A (en) 2009-02-25 2012-04-04 康复米斯公司 Patient-adapted and improved orthopedic implants, designs and related tools
US20110071645A1 (en) 2009-02-25 2011-03-24 Ray Bojarski Patient-adapted and improved articular implants, designs and related guide tools
SG173840A1 (en) 2009-02-25 2011-09-29 Conformis Inc Patient-adapted and improved orthopedic implants, designs and related tools
WO2010099353A1 (en) 2009-02-25 2010-09-02 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
US20110071802A1 (en) 2009-02-25 2011-03-24 Ray Bojarski Patient-adapted and improved articular implants, designs and related guide tools
US20100262150A1 (en) 2009-04-13 2010-10-14 George John Lian Custom radiographically designed cutting guides and instruments for use in total ankle replacement surgery
AU2010236263A1 (en) 2009-04-16 2011-11-10 Conformis, Inc. Patient-specific joint arthroplasty devices for ligament repair
SG175229A1 (en) 2009-04-16 2011-11-28 Conformis Inc Patient-specific joint arthroplasty devices for ligament repair
CN102448394A (en) 2009-04-16 2012-05-09 康复米斯公司 Patient-specific joint arthroplasty devices for ligament repair
JP2012523897A (en) 2009-04-16 2012-10-11 コンフォーミス・インコーポレイテッドConforMIS, Inc. Patient-specific joint replacement of the device for ligament repair
WO2010121147A1 (en) 2009-04-16 2010-10-21 Conformis, Inc. Patient-specific joint arthroplasty devices for ligament repair
EP2419035A1 (en) 2009-04-16 2012-02-22 ConforMIS, Inc. Patient-specific joint arthroplasty devices for ligament repair
US20100286700A1 (en) 2009-05-07 2010-11-11 Smith & Nephew, Inc. Patient specific alignment guide for a proximal femur
US20120172884A1 (en) 2009-06-17 2012-07-05 University Of Bern Methods and devices for patient-specific acetabular component alignment in total hip arthroplasty
CA2765499A1 (en) 2009-06-24 2010-12-29 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
NZ597261A (en) 2009-06-24 2013-11-29 Conformis Inc Patient-adapted and improved orthopedic implants, designs and related tools
EP2445451A1 (en) 2009-06-24 2012-05-02 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
AU2010264466A1 (en) 2009-06-24 2012-02-02 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
JP2012531265A (en) 2009-06-24 2012-12-10 コンフォーミス・インコーポレイテッドConforMIS, Inc. Patient-improved orthopedic implants, design and related tools
GB2484042A (en) 2009-06-24 2012-03-28 Conformis Patient-adapted and improved orthpedic implants, designs and related tools
SG176833A1 (en) 2009-06-24 2012-01-30 Conformis Inc Patient-adapted and improved orthopedic implants, designs and related tools
KR20120102576A (en) 2009-06-24 2012-09-18 콘포미스 인코퍼레이티드 Patient-adapted and improved orthopedic implants, designs and related tools
US20110015637A1 (en) 2009-07-17 2011-01-20 Materialise N.V. Surgical guiding tool, methods for manufacture and uses thereof
US20120165820A1 (en) 2009-07-17 2012-06-28 Karla De Smedt Surgical guiding tool, methods for manufacture and uses thereof
US20110196377A1 (en) 2009-08-13 2011-08-11 Zimmer, Inc. Virtual implant placement in the or
US20120209276A1 (en) 2009-08-13 2012-08-16 Biomet Manufacturing Corp. Device for the resection of bones, method for producing such a device, endoprosthesis suited for this purpose and method for producing such an endoprosthesis
WO2011028624A1 (en) 2009-08-26 2011-03-10 Conformis, Inc. Patient-specific orthopedic implants and models
EP2470126A1 (en) 2009-08-26 2012-07-04 Conformis, Inc. Patient-specific orthopedic implants and models
JP2013503007A (en) 2009-08-26 2013-01-31 コンフォーミス・インコーポレイテッドConforMIS, Inc. Patient-specific orthopedic implant and model
KR20120090997A (en) 2009-08-26 2012-08-17 콘포미스 인코퍼레이티드 Patient-specific orthopedic implants and models
CN102711670A (en) 2009-08-26 2012-10-03 康复米斯公司 Patient-specific orthopedic implants and models
SG178836A1 (en) 2009-08-26 2012-04-27 Conformis Inc Patient-specific orthopedic implants and models
AU2010289706A1 (en) 2009-08-26 2012-03-29 Conformis, Inc. Patient-specific orthopedic implants and models
CA2771573A1 (en) 2009-08-26 2011-03-10 Conformis, Inc. Patient-specific orthopedic implants and models
US20110060341A1 (en) 2009-09-10 2011-03-10 Laurent Angibaud Alignment guides for use in computer assisted orthopedic surgery to prepare a bone element for an implant
US20110106093A1 (en) 2009-10-29 2011-05-05 Zimmer, Inc. Patient-specific mill guide
WO2011056995A2 (en) 2009-11-04 2011-05-12 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
EP2496183A2 (en) 2009-11-04 2012-09-12 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
GB201213674D0 (en) 2009-11-04 2012-09-12 Conformis Patient-adapted and improved orthopedic implants, designs and related tools
CA2779283A1 (en) 2009-11-04 2011-05-12 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
AU2010315099A1 (en) 2009-11-04 2012-05-31 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
CN102724934A (en) 2009-11-04 2012-10-10 康复米斯公司 Patient-adapted and improved orthopedic implants, designs and related tools
GB2489884A (en) 2009-11-04 2012-10-10 Conformis Patient-adapted and improved orthopedic implants, designs and related tools
US20120245647A1 (en) 2009-11-17 2012-09-27 Manuela Kunz Patient-Specific Guide for Acetabular Cup Placement
WO2011072235A2 (en) 2009-12-11 2011-06-16 Conformis, Inc. Patient-specific and patient-engineered orthopedic implants
CA2782137A1 (en) 2009-12-11 2011-06-16 Conformis, Inc. Patient-specific and patient-engineered orthopedic implants
EP2509539A2 (en) 2009-12-11 2012-10-17 Conformis, Inc. Patient-specific and patient-engineered orthopedic implants
AU2010327987A1 (en) 2009-12-11 2012-06-14 Conformis, Inc. Patient-specific and patient-engineered orthopedic implants
EP2512381A2 (en) 2009-12-18 2012-10-24 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
MX2012007140A (en) 2009-12-18 2013-01-24 Conformis Inc Patient-adapted and improved orthopedic implants, designs and related tools.
WO2011075697A2 (en) 2009-12-18 2011-06-23 Conformis, Inc. Patient-adapted and improved orthopedic implants, designs and related tools
US20110213376A1 (en) 2010-02-26 2011-09-01 Biomet Sports Medicine, Llc Patient-Specific Osteotomy Devices and Methods
US20110218545A1 (en) 2010-03-04 2011-09-08 Biomet Manufacturing Corp. Patient-specific computed tomography guides
US20120078258A1 (en) 2010-03-31 2012-03-29 Darrick Lo Shoulder arthroplasty instrumentation
US20110275957A1 (en) 2010-05-06 2011-11-10 Sachin Bhandari Inertial Sensor Based Surgical Navigation System for Knee Replacement Surgery
US20120123422A1 (en) 2010-06-11 2012-05-17 Aashiish Agnihotri Patient-Matched Instruments
US20120116562A1 (en) 2010-06-11 2012-05-10 Smith & Nephew, Inc. Systems and methods Utilizing Patient-Matched Instruments
US20120010711A1 (en) 2010-06-11 2012-01-12 Antonyshyn Oleh Method of forming patient-specific implant
US20110313424A1 (en) 2010-06-18 2011-12-22 Howmedica Osteonics Corp. Patient-specific total hip arthroplasty
US20120041445A1 (en) 2010-08-12 2012-02-16 Roose Jeffrey R Customized patient-specific acetabular orthopaedic surgical instrument and method of use and fabrication
US20120130382A1 (en) 2010-09-07 2012-05-24 The Cleveland Clinic Foundation Positioning apparatus and method for a prosthetic implant
US20120078254A1 (en) 2010-09-29 2012-03-29 Depuy Products, Inc. Customized patient-specific computer controlled cutting system and method
US20120078259A1 (en) 2010-09-29 2012-03-29 Biomet Manufacturing Corp. Patient-specific guide for partial acetabular socket replacement
US20120141034A1 (en) 2010-10-29 2012-06-07 The Cleveland Clinic Foundation System of preoperative planning and provision of patient-specific surgical aids
US20120276509A1 (en) 2010-10-29 2012-11-01 The Cleveland Clinic Foundation System of preoperative planning and provision of patient-specific surgical aids
US20120116203A1 (en) 2010-11-10 2012-05-10 Wilfried Vancraen Additive manufacturing flow for the production of patient-specific devices comprising unique patient-specific identifiers
US20120123423A1 (en) 2010-11-11 2012-05-17 Zimmer, Inc. Patient-specific instruments for total hip arthroplasty
WO2012112702A2 (en) 2011-02-15 2012-08-23 Conformis, Inc. Patient-adapted and improved articular implants, designs and related guide tools
CN103476363A (en) 2011-02-15 2013-12-25 康复米斯公司 Patient-adapted and improved articular implants, procedures and tools to address, assess, correct, modify and/or accommodate anatomical variation and/or asymmetry
WO2012112698A2 (en) 2011-02-15 2012-08-23 Conformis, Inc. Patient-adapted and improved articular implants, procedures and tools to address, assess, correct, modify and/or accommodate anatomical variation and/or asymmetry
WO2012112701A2 (en) 2011-02-15 2012-08-23 Conformis, Inc. Patent-adapted and improved articular implants, designs, surgical procedures and related guide tools
WO2012112694A2 (en) 2011-02-15 2012-08-23 Conformis, Inc. Medeling, analyzing and using anatomical data for patient-adapted implants. designs, tools and surgical procedures
SG193484A1 (en) 2011-02-15 2013-10-30 Conformis Inc Patent-adapted and improved articular implants, designs, surgical procedures and related guide tools
AU2012217654A1 (en) 2011-02-15 2013-10-03 Conformis, Inc. Patient-adapted and improved articular implants, procedures and tools to address, assess, correct, modify and/or accommodate anatomical variation and/or asymmetry
US20120239045A1 (en) 2011-03-17 2012-09-20 Zimmer, Inc. Patient-specific instruments for total ankle arthroplasty
US20120259420A1 (en) 2011-04-06 2012-10-11 Lashure Daniel E Proximal trial instrument for use during an orthopaedic surgical procedure to implant a revision hip prosthesis
US20120265208A1 (en) 2011-04-15 2012-10-18 Biomet Manufacturing Corp. Patient-specific numerically controlled instrument
US20120271366A1 (en) 2011-04-19 2012-10-25 Biomet Manufacturing Corp. Patient-specific fracture fixation instrumentation and method
US20120277751A1 (en) 2011-04-29 2012-11-01 Biomet Manufacturing Corp. Patient-specific convertible guides
US20120296339A1 (en) 2011-05-19 2012-11-22 Iannotti Joseph P Apparatus and method for providing a reference indication to a patient tissue
AU2012289973A1 (en) 2011-08-03 2014-03-20 Conformis, Inc. Automated design, selection, manufacturing and implantation of patient-adapted and improved articular implants, designs and related guide tools
WO2013020026A1 (en) 2011-08-03 2013-02-07 Conformis, Inc. Automated design, selection, manufacturing and implantation of patient-adapted and improved articular implants, designs and related guide tools
AU2012296556A1 (en) 2011-08-15 2014-03-20 Conformis, Inc. Revision systems, tools and methods for revising joint arthroplasty implants
WO2013025814A1 (en) 2011-08-15 2013-02-21 Conformis, Inc. Revision systems, tools and methods for revising joint arthroplasty implants
WO2013056036A1 (en) 2011-10-14 2013-04-18 Conformis, Inc. Methods and systems for identification, assessment, modeling, and repair of anatomical disparities in joint replacement
US20130184713A1 (en) 2011-12-23 2013-07-18 Conformis, Inc. Anatomical Alignment Systems and Methods
WO2013119790A1 (en) 2012-02-07 2013-08-15 Conformis, Inc. Tibial implant devices, systems, and methods
WO2013119865A1 (en) 2012-02-07 2013-08-15 Conformis Inc Joint arthroplasty devices, systems, and methods
US20130211410A1 (en) 2012-02-07 2013-08-15 Conformis, Inc. Patella Resection Instrument Guide Having Optional Patient-Specific Features
WO2013131066A1 (en) 2012-03-02 2013-09-06 Conformis, Inc. Patient-adapted posterior stabilized knee implants, designs and related methods and tools
WO2013136302A1 (en) 2012-03-16 2013-09-19 Custom Med Orthopaedics Proprietary Limited A bone cutting guide and a bone cutting guide system
WO2013152341A1 (en) 2012-04-06 2013-10-10 Conformis, Inc. Advanced methods, techniques, devices, and systems for cruciate retaining knee implants
WO2013155500A1 (en) 2012-04-13 2013-10-17 Conformis, Inc. Devices and methods for additive manufacturing of implant components
WO2013155501A1 (en) 2012-04-13 2013-10-17 Conformis, Inc. Patient adapted joint arthroplasty devices, surgical tools and methods of use
US20130296874A1 (en) 2012-04-18 2013-11-07 Conformis, Inc. Tibial guides, tools, and techniques for resecting the tibial plateau
US20130289570A1 (en) 2012-04-27 2013-10-31 Conformis, Inc. Tibial Template and Punch System, Tools and Methods for Preparing the Tibia
US20130297031A1 (en) 2012-05-02 2013-11-07 Conformis, Inc. Patient specific instruments and related methods for joint replacement
US20130296865A1 (en) * 2012-05-04 2013-11-07 Luke J. Aram Customized patient-specific orthopaedic pin guides
US20130331850A1 (en) 2012-06-11 2013-12-12 Conformis, Inc. Devices, techniques and methods for assessing joint spacing, balancing soft tissues and obtaining desired kinematics for joint implant components
WO2014008444A1 (en) 2012-07-03 2014-01-09 Conformis, Inc. Devices, systems, and methods for impacting joint implant components
WO2014035991A1 (en) 2012-08-27 2014-03-06 Conformis, Inc. Methods, devices and techniques for improved placement and fixation of shoulder implant components
US20140086780A1 (en) 2012-09-21 2014-03-27 Conformis, Inc. Methods and systems for optimizing design and manufacture of implant components using solid freeform fabrication
WO2014047514A1 (en) 2012-09-21 2014-03-27 Conformis, Inc. Methods and systems for optimizing design and manufacture of implant components using solid freeform fabrication

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Hofmann et al, "Natural-Knee II System", Intermedics Orthopedics, Austin, TX, 1995.
Taylor et al, "Computer-Integrated Surgery, Technology and Clinical Applications", The MIT Press, Cambridge, MA, London, UK, pp. 451-463.

Also Published As

Publication number Publication date
CN106456192A (en) 2017-02-22
EP3151759A1 (en) 2017-04-12
WO2015187822A1 (en) 2015-12-10
CA2947773A1 (en) 2015-12-10
US20150347710A1 (en) 2015-12-03
EP3151759A4 (en) 2018-02-21
US20190148022A1 (en) 2019-05-16

Similar Documents

Publication Publication Date Title
CA2752880C (en) Patient specific surgical guide locator and mount
EP2712301B1 (en) Apparatus for providing a reference indication to a patient tissue
CA2778057C (en) Patient-specific mill guide
US5607431A (en) Prosthetic hip implantation method and apparatus
US9539013B2 (en) Patient-specific elbow guides and associated methods
US8979936B2 (en) Patient-modified implant
US9936962B2 (en) Patient specific glenoid guide
US10258352B2 (en) System and method for assisting with attachment of a stock implant to a patient tissue
RU2570313C2 (en) Methods and devices for knee-joint arthroplasty
US8535387B2 (en) Patient-specific tools and implants
AU2011226351B2 (en) Orthopaedic instrument
KR101534181B1 (en) Orthopedic surgical guide
US9579107B2 (en) Multi-point fit for patient specific guide
US8992538B2 (en) Customized patient-specific acetabular orthopaedic surgical instrument and method of use and fabrication
US9017336B2 (en) Arthroplasty devices and related methods
US9289253B2 (en) Patient-specific shoulder guide
US9095353B2 (en) Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty
US8979856B2 (en) Patient-specific partial knee guides and other instruments
CN103338714B (en) Positioning apparatus prosthesis implantation portion
US9826981B2 (en) Tangential fit of patient-specific guides
US20100137924A1 (en) Tool
EP2770953B1 (en) Method for forming a mold
US9351743B2 (en) Patient-specific glenoid guides
EP1813215A1 (en) Tool
US10278711B2 (en) Patient-specific femoral guide

Legal Events

Date Code Title Description
AS Assignment

Owner name: ZIMMER, INC., INDIANA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:COUTURE, PIERRE;MASSE, VINCENT;NEUROHR, ANSELM JAKOB;SIGNING DATES FROM 20150807 TO 20150813;REEL/FRAME:036727/0335

STCF Information on status: patent grant

Free format text: PATENTED CASE