US1012788A - Medicinal composition containing oil. - Google Patents
Medicinal composition containing oil. Download PDFInfo
- Publication number
- US1012788A US1012788A US49154309A US1909491543A US1012788A US 1012788 A US1012788 A US 1012788A US 49154309 A US49154309 A US 49154309A US 1909491543 A US1909491543 A US 1909491543A US 1012788 A US1012788 A US 1012788A
- Authority
- US
- United States
- Prior art keywords
- peat
- oils
- medicinal
- oil
- castor oil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title description 20
- 239000003921 oil Substances 0.000 description 38
- 235000019198 oils Nutrition 0.000 description 38
- 239000003415 peat Substances 0.000 description 29
- 239000004359 castor oil Substances 0.000 description 24
- 229960001777 castor oil Drugs 0.000 description 23
- 235000019438 castor oil Nutrition 0.000 description 23
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 23
- 239000000463 material Substances 0.000 description 12
- 238000000034 method Methods 0.000 description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- 239000002253 acid Substances 0.000 description 8
- 238000001035 drying Methods 0.000 description 8
- 229910000162 sodium phosphate Inorganic materials 0.000 description 7
- 239000001488 sodium phosphate Substances 0.000 description 7
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 7
- 239000000843 powder Substances 0.000 description 5
- 239000011261 inert gas Substances 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- 230000001131 transforming effect Effects 0.000 description 4
- 206010013911 Dysgeusia Diseases 0.000 description 3
- 150000007513 acids Chemical class 0.000 description 3
- 230000000249 desinfective effect Effects 0.000 description 3
- 238000004898 kneading Methods 0.000 description 3
- 230000007721 medicinal effect Effects 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- 210000002784 stomach Anatomy 0.000 description 3
- 239000003026 cod liver oil Substances 0.000 description 2
- 239000000645 desinfectant Substances 0.000 description 2
- 239000008157 edible vegetable oil Substances 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 239000005418 vegetable material Substances 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 235000012716 cod liver oil Nutrition 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000001877 deodorizing effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000001804 emulsifying effect Effects 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000009877 rendering Methods 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000009738 saturating Methods 0.000 description 1
- 239000002195 soluble material Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/42—Phosphorus; Compounds thereof
Definitions
- This invention relates more particularly to solidifying castor oil, cod-liver: oil and similar medical oils for medicinal purposes.
- the primaryobjectiof the invention is to provide a rocess for 'deodorizing and rendering disinfectant, preserving, fying medical oils and the like which are of a very objectionable characten'such for example as castor oil and cod-liver oil, which are objectionable to take, owing to the repugnant taste and smell, and atthe same time solidifying such oils so that the same may be conveniently handled and'taken; and to provide a process which will add to these oils antiseptic and also disinfecting qualities which is especially needed in all troubles of the stomach and intestinaltract, still retaining their excellent medical-virtues and en- 1 tirely removing their objectionable taste and smell.
- Another object ofthe invention is to provide an article of manufacture in'the form ofsolidified castor oil andv other medicinal oils.
- a further object of-the invention is to so combine the oilw-itha material or materials that the same-may be .put up. 1n the form of l powder or tablets and in other convenient ways.
- moss as well as its product by natural oxidation generally called peat moss or peat
- peat moss fulfils more completely the many conditions required to secure the desirable results mentioned than any other material heretofore used. This is especially true considering the fact that moss as well as peat 'is a highly absorbent material absorbingliquids many times its own weight.
- Moss as well as peat owing to the fact that they contain certain organic matters are very satisfactory disinfectants, and stop especially fermentation and decomposition of organic substances, and this is particularly desirable in oils such as cod-liver and castor oils for the reason that such oils if exposed to the atmosphere "will become rancid after a very short time.
- Both moss and peat are easily digested and also have considerable'value as food. I 'find that moss as well as peat readily absorb castor oil and remove entirely all disagreeable and nauseating taste,,and afford a way. to administer castor oil inan agreeable and palatable form,
- peat once dried does-not take up water again because those colloidal matters make it impermeable towater.
- peat heavily saturated with castor oil may be easily the preparationof castor oil, etc.,- for internal use, as it ofi'ers away of surely and positively excluding the access of air to the castor oil.
- a mixture is secured,.which, if the oily character of the mixture is notconsidcred, appears to be dry.
- the water-soaked pulp after due kneading to make a dough of the same is spread on a tray or similar device, and is then put into a drying appa-.
- the material may be dried in a vacuum chamber or in a closed vessel into which carbon dioxid or a like inert gas is passed to exclude the influence of the oxy- In a relatively short time,
- the dough may be disintegrated into fine powder, and ifnecessary may be mixed with sugar and then formed'into tablets or any other form which may be decided on.
- the sugar by dissolving in the water will fill up all the channels represented by the pores of the moss or peat, and by successive drying by heat, the dry sugar will fill up all the cells or pores, and will then'form a coat or crust which in a; very effective way keeps off the oxygen of the air and assistsm protecting the castor oil from becoming rancid.
- 'It is a special afte'r'due drying, the mixture of moss or feature of the process that peat with castor oil or such like medical oils may be disintegrated to be formed into tablets or in any convenientform fit for internal use.
- the peat and the moss contain humous acid and ulmic acid, and also colloidal bodies, and these bodies and acids serve to act on the oils to assist in preventing the oils from becoming. rancid," as some of the oils, particularlycod-liver oil, become ran cid in a very" short time when exposed to the air, and it will be understood that the introduction of these acids may be made either vwith the materials mentioned as forming an element of the natural condition of the material, or the same may be introduced in other ways if desired.
- oils having medicinal properties may, by the process and means herein mentioned, be converted into a solidified body to adapt the same to be made into-tablets or other forms convenient for use; that said oils will have the bad taste and odor removed therefrom; that by .treating the oils according to the process or method herein disclosed, the
- beneficial andmedicinal properties of the oils are not injured; and that the material employed for treating the oils is not only digestible but also serves as disinfecting means for the'stomach and intestinal tract.
- the processof treating medicinal oils which comprises mixing medicinal oils'with peat, and after adding water to this mixture transforming the mixture into pulp, adding suitable soluble medicinal salts to the pulp, kneading the mixture, drying the product resulting therefrom at a moderate temperature while subjecting the same to an inert gas to exclude the action 'of air, and finally disintegrating the product to a fine powder.
- the product of treating medicinal oils which comprises mixing medicinal oil with peat, transforming the mixture into-pulp with water, lmeading the mixture, drying the product resulting therefrom at a mod: erate temperature, while subjecting the same to an inert gas to exclude the action of air, and finally disintegrating the product into a fine powder.
- a medicinal composition comprising castor oil and eat.
- a tablet which comprises castor oil,
- a medicinal preparation comprising castor oil, peat, and sodium phosphate in substantially the proportion specified.
- a tablet comprising an edible oil having medicinal properties, disintegrated peat, sugar and sodium phosphate.
- a tablet comprising an edible oil having medicinal properties, peat and sodium phosphate.
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Description
orro K. zwrnennnnaona on NEW roan, n. Y.
MEDICINAL ooMro srrron CONTAINING 01 n No Drawing.
Specification of Letters Patent. Application filed April 22, 1909. Serial No. 491,543.
Patented Dec. 26, 1911.
To all whom it may concern:
Be it known that I, Orrro K. ZWINGEN- BERGER, a subject of the Emperor of Germany, and a resident of New York, county and State of New York, have invented cer-. tain new and useful Improvements in Medicinal Compositions Containing Oil, of which the following is a full, clear, and exact description.
This invention relates more particularly to solidifying castor oil, cod-liver: oil and similar medical oils for medicinal purposes.
The primaryobjectiof the invention is to providea rocess for 'deodorizing and rendering disinfectant, preserving, fying medical oils and the like which are of a very objectionable characten'such for example as castor oil and cod-liver oil, which are objectionable to take, owing to the repugnant taste and smell, and atthe same time solidifying such oils so that the same may be conveniently handled and'taken; and to provide a process which will add to these oils antiseptic and also disinfecting qualities which is especially needed in all troubles of the stomach and intestinaltract, still retaining their excellent medical-virtues and en- 1 tirely removing their objectionable taste and smell. g
Another object ofthe inventionis to provide an article of manufacture in'the form ofsolidified castor oil andv other medicinal oils.
A further object of-the invention is to so combine the oilw-itha material or materials that the same-may be .put up. 1n the form of l powder or tablets and in other convenient ways.
' iththeseand other objects in view,- the invention willbe hereinafter more particularly described, .and lthe'n pointed out in the claims at the end of the description.
It has been Twellf known that it would be very des'irable,- zifffor"example castor oil' could be relieved of gitsbad taste and at the same time .rende'redjdisinfectant, that such aproc'ess as wella's thefarticle would possess great'a'dvantago Qverthe common means employed to simply disguise the bad taste and odor of the oils. Many attempts have been made to overcome the objections to-the oils referred to by combining variousliquids, as
"and solidiflavors, etc., and by emulsifying the oil, but such methods and others haveproved very unsatisfactory.
It is well known that mixtures with flavors and the like are only a partial success, and it is important to combine with such oils a material which will not impair the medical virtues of castor oil or other oils,
but which will remove the bad taste and which will bring into eil'ect the natural medical qualities of the oils, and particularly castor oil in the shortest possible time a after taking the same and simultaneously disinfecting the stomach and the intestines.
I have discovered that moss as well as its product by natural oxidation generally called peat moss or peat, fulfils more completely the many conditions required to secure the desirable results mentioned than any other material heretofore used. This is especially true considering the fact that moss as well as peat 'is a highly absorbent material absorbingliquids many times its own weight. Moss as well as peat owing to the fact that they contain certain organic matters are very satisfactory disinfectants, and stop especially fermentation and decomposition of organic substances, and this is particularly desirable in oils such as cod-liver and castor oils for the reason that such oils if exposed to the atmosphere "will become rancid after a very short time. Both moss and peat are easily digested and also have considerable'value as food. I 'find that moss as well as peat readily absorb castor oil and remove entirely all disagreeable and nauseating taste,,and afford a way. to administer castor oil inan agreeable and palatable form,
tive. Both these vegetable materials conretaining all its active properties as a laxatain organic matters especially organic acids,
and in the case of peat, humous acid and ulmic acid which act on; the castor oil in the:
way of neutralizing for saturating certain components of the castor-oil, thus-taking;
from the latter the repugnant taste without exerting a' saponifyi-ng action of the 'principal partof the castor oil. Besldes those acids mentioned .both moss and peat contain certain colloidal matters which are of the greatest in their relation to 'eitliermos'sor peat and castor oil, as these colloidal matters prevent wet peat from be ing dried except with considerable difliculty,
and peat once dried does-not take up water again because those colloidal matters make it impermeable towater. Owing to the .colloidal matters I have found that peat heavily saturated with castor oil may be easily the preparationof castor oil, etc.,- for internal use, as it ofi'ers away of surely and positively excluding the access of air to the castor oil. I
As one method of carrying my invention into effect and for making cast-or oil tablets and the like, I take the following materialsone pound of castor oil; one and one-.
half pounds of disintegrated dried peat; and one-pound of sugar; and one and one-half ounces of sodium phosphate, and about three-quarters of a pint of water.
The oil i's poured into a dish or other vessel and finely powdered peat is added to the oil until a mixture is secured,.which, if the oily character of the mixture is notconsidcred, appears to be dry. To this powdered mixture of peat and oil, enough water is added to make a soft pulp, and to thispulp I may add sugar, starch or like vegetable material, and to this may be added sodium phosphate or some other soluble salts, but preferably such as are valuable in building up and strengthening the human body. By adding these materials the water-soaked pulp after due kneading to make a dough of the same is spread on a tray or similar device, and is then put into a drying appa-.
ratus, to be dried at a gentle heat in the open air, or the material may be dried in a vacuum chamber or in a closed vessel into which carbon dioxid or a like inert gas is passed to exclude the influence of the oxy- In a relatively short time,
gen of the air. the dough may be disintegrated into fine powder, and ifnecessary may be mixed with sugar and then formed'into tablets or any other form which may be decided on.
When the material is in-a wet state and sugar or like soluble material is added to the mixture, the sugar by dissolving in the water will fill up all the channels represented by the pores of the moss or peat, and by successive drying by heat, the dry sugar will fill up all the cells or pores, and will then'form a coat or crust which in a; very effective way keeps off the oxygen of the air and assistsm protecting the castor oil from becoming rancid.
'It is a special afte'r'due drying, the mixture of moss or feature of the process that peat with castor oil or such like medical oils may be disintegrated to be formed into tablets or in any convenientform fit for internal use. 1 7
When. the peat or moss is used in a wet state the proportion of water is correspondingly changed, and it will be also understood that the proportions" of the other ingredients will be varied according to the strength or nature of the article to be made.
The peat and the moss contain humous acid and ulmic acid, and also colloidal bodies, and these bodies and acids serve to act on the oils to assist in preventing the oils from becoming. rancid," as some of the oils, particularlycod-liver oil, become ran cid in a very" short time when exposed to the air, and it will be understood that the introduction of these acids may be made either vwith the materials mentioned as forming an element of the natural condition of the material, or the same may be introduced in other ways if desired.
From the foregoing it will be seen that i I oils having medicinal properties may, by the process and means herein mentioned, be converted into a solidified body to adapt the same to be made into-tablets or other forms convenient for use; that said oils will have the bad taste and odor removed therefrom; that by .treating the oils according to the process or method herein disclosed, the
beneficial andmedicinal properties of the oils are not injured; and that the material employed for treating the oils is not only digestible but also serves as disinfecting means for the'stomach and intestinal tract.
Having thus described my'invention', .I claim as newand desire to secure by Letters Patent 1. The process of treating medicinal oils, which comprises mixing the same with a material containing ulmicacid, humous acid and colloidal matter, and then drying the resulting product while subjected to an inert gas to prevent access of the air thereto.
'2. The processof treating medicinal oils which comprises mixing medicinal oils'with peat, and after adding water to this mixture transforming the mixture into pulp, adding suitable soluble medicinal salts to the pulp, kneading the mixture, drying the product resulting therefrom at a moderate temperature while subjecting the same to an inert gas to exclude the action 'of air, and finally disintegrating the product to a fine powder.
3. The process of treating medicinal oils.
which comprises .mlx-ing a medicinal oil with peat, adding water to this mixture,
ing the mixture, drying the product resulting therefrom at a moderate temperature, and finally. disintegrating the product ,into a fine powder.
, transforming the mixture into pulp, knead- 4. The product of treating medicinal oils which comprises mixing medicinal oil with peat, transforming the mixture into-pulp with water, lmeading the mixture, drying the product resulting therefrom at a mod: erate temperature, while subjecting the same to an inert gas to exclude the action of air, and finally disintegrating the product into a fine powder.
5. The process of treating medicinal oils which comprises mixing a medicinal oil with peat, adding water to this -mixture,
transforming the mixture into pulp, addmg sugar and a suitable soluble medicinal salt to the pulp, kneading the mixture, and drying the product resulting therefrom.
6. As an article of manufacture, a medicinal composition comprising castor oil and eat.
7.'A tablet comprising castor oil, disintegrated dried peat, sugar and sodium phosphate.
8. A tablet which comprises castor oil,
a and disintegrated dried peat.
9. A medicinal preparatlon containing castor oil, peat, sugar and sodium phosphate in substantially the proportion speci- 10. A medicinal preparation comprising castor oil, peat, and sodium phosphate in substantially the proportion specified.
11. A tablet comprising an edible oil having medicinal properties, disintegrated peat, sugar and sodium phosphate.
12. A tablet comprising an edible oil having medicinal properties, peat and sodium phosphate.
This specification signed and witnessed this 19 day of April A. D. 1909.
OTTO K. ZWINGENBERGER. Witnesses:
M. F. KEATING, M. DmNHAnr'r.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49154309A US1012788A (en) | 1909-04-22 | 1909-04-22 | Medicinal composition containing oil. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49154309A US1012788A (en) | 1909-04-22 | 1909-04-22 | Medicinal composition containing oil. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| US1012788A true US1012788A (en) | 1911-12-26 |
Family
ID=3081096
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US49154309A Expired - Lifetime US1012788A (en) | 1909-04-22 | 1909-04-22 | Medicinal composition containing oil. |
Country Status (1)
| Country | Link |
|---|---|
| US (1) | US1012788A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2809918A (en) * | 1955-10-17 | 1957-10-15 | Victor M Hermelin | Sustained release pharmaceutical preparations |
| US2809916A (en) * | 1955-10-17 | 1957-10-15 | Victor M Hermelin | Sustained release pharmaceutical preparations |
| US12330458B2 (en) | 2022-02-25 | 2025-06-17 | Santo A. Padula | Trucks and trailers with power conversion elements and suspension systems accommodating power conversion elements inboard of a wheel |
-
1909
- 1909-04-22 US US49154309A patent/US1012788A/en not_active Expired - Lifetime
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2809918A (en) * | 1955-10-17 | 1957-10-15 | Victor M Hermelin | Sustained release pharmaceutical preparations |
| US2809916A (en) * | 1955-10-17 | 1957-10-15 | Victor M Hermelin | Sustained release pharmaceutical preparations |
| US12330458B2 (en) | 2022-02-25 | 2025-06-17 | Santo A. Padula | Trucks and trailers with power conversion elements and suspension systems accommodating power conversion elements inboard of a wheel |
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