UA99469C2 - Fused thiazole derivatives as kinase inhibitors - Google Patents

Fused thiazole derivatives as kinase inhibitors

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Publication number
UA99469C2
UA99469C2 UAA201000774A UAA201000774A UA99469C2 UA 99469 C2 UA99469 C2 UA 99469C2 UA A201000774 A UAA201000774 A UA A201000774A UA A201000774 A UAA201000774 A UA A201000774A UA 99469 C2 UA99469 C2 UA 99469C2
Authority
UA
Ukraine
Prior art keywords
kinase inhibitors
thiazole derivatives
fused thiazole
substituted
derivatives
Prior art date
Application number
UAA201000774A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Рикки Питер Александер
Павандип Сингх Ауджла
Карен Вивьен Люсиль Крепи
Энни Мари Фоли
Ричард Джереми Франклин
Original Assignee
Юсиби Фарма, С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/GB2007/002390 external-priority patent/WO2008001076A1/en
Application filed by Юсиби Фарма, С.А. filed Critical Юсиби Фарма, С.А.
Publication of UA99469C2 publication Critical patent/UA99469C2/en

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    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
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    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

A series of 6,7-dihydro[l,3]thiazolo[5,4-c]pyridin-4(5H)-one derivatives, which are substituted in the 2-position by a substituted morpholin-4-yl moiety, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.
UAA201000774A 2007-06-26 2008-06-24 Fused thiazole derivatives as kinase inhibitors UA99469C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/GB2007/002390 WO2008001076A1 (en) 2006-06-26 2007-06-26 Fused thiazole derivatives as kinase inhibitors

Publications (1)

Publication Number Publication Date
UA99469C2 true UA99469C2 (en) 2012-08-27

Family

ID=39737000

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201000774A UA99469C2 (en) 2007-06-26 2008-06-24 Fused thiazole derivatives as kinase inhibitors

Country Status (8)

Country Link
JP (1) JP5570981B2 (en)
KR (1) KR101577314B1 (en)
BR (1) BRPI0813777B8 (en)
HK (1) HK1140756A1 (en)
NZ (1) NZ581919A (en)
SI (1) SI2170906T1 (en)
UA (1) UA99469C2 (en)
WO (1) WO2009001089A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010135504A1 (en) * 2009-05-20 2010-11-25 Glaxosmithkline Llc Thiazolopyrimidinone derivatives as pi3 kinase inhibitors
WO2012071511A1 (en) * 2010-11-24 2012-05-31 Exelixis, Inc. Benzoxazepines as inhibitors of mtor and methods of their use and manufacture
WO2020056269A1 (en) * 2018-09-13 2020-03-19 Stemline Therapeutics, Inc. Methods for treating centronuclear myopathy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0508471D0 (en) * 2005-04-26 2005-06-01 Celltech R&D Ltd Therapeutic agents

Also Published As

Publication number Publication date
SI2170906T1 (en) 2013-07-31
BRPI0813777B8 (en) 2021-05-25
BRPI0813777B1 (en) 2020-12-08
JP5570981B2 (en) 2014-08-13
KR20100040736A (en) 2010-04-20
NZ581919A (en) 2011-08-26
JP2011504164A (en) 2011-02-03
HK1140756A1 (en) 2010-10-22
BRPI0813777A2 (en) 2014-12-30
KR101577314B1 (en) 2015-12-14
WO2009001089A1 (en) 2008-12-31

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