UA97249C2 - Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors for inhibiting the growth of tumor cells - Google Patents

Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors for inhibiting the growth of tumor cells

Info

Publication number
UA97249C2
UA97249C2 UAA200900388A UAA200900388A UA97249C2 UA 97249 C2 UA97249 C2 UA 97249C2 UA A200900388 A UAA200900388 A UA A200900388A UA A200900388 A UAA200900388 A UA A200900388A UA 97249 C2 UA97249 C2 UA 97249C2
Authority
UA
Ukraine
Prior art keywords
class
inhibiting
growth
inhibitors
tumor cells
Prior art date
Application number
UAA200900388A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Жанин Артс
Петер Виллем Ян Хеллеманс
Мишель Мари Франсуа Жанико
Мартин Джон Пейдж
Original Assignee
Янссен Фармацевтика Нв
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Янссен Фармацевтика Нв filed Critical Янссен Фармацевтика Нв
Priority claimed from PCT/EP2007/059518 external-priority patent/WO2008031817A2/en
Publication of UA97249C2 publication Critical patent/UA97249C2/en

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention is concerned with combinations of a proteasome inhibitor and a histone deacetylase inhibitor with combined activity on class-I and class -IIB histone deacetylases, for inhibiting the growth of tumor cells, useful in the treatment of cancer.
UAA200900388A 2006-09-15 2007-09-11 Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors for inhibiting the growth of tumor cells UA97249C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06120726 2006-09-15
PCT/EP2007/059518 WO2008031817A2 (en) 2006-09-15 2007-09-11 Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors

Publications (1)

Publication Number Publication Date
UA97249C2 true UA97249C2 (en) 2012-01-25

Family

ID=41040414

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200900388A UA97249C2 (en) 2006-09-15 2007-09-11 Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors for inhibiting the growth of tumor cells

Country Status (12)

Country Link
CN (1) CN101516374B (en)
BR (1) BRPI0716992A2 (en)
DK (1) DK2066327T3 (en)
ES (1) ES2399670T3 (en)
ME (1) ME01514B (en)
NZ (1) NZ575030A (en)
PT (1) PT2066327E (en)
RS (1) RS52638B (en)
SG (1) SG177219A1 (en)
SI (1) SI2066327T1 (en)
UA (1) UA97249C2 (en)
ZA (1) ZA200901818B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115028678A (en) * 2022-07-08 2022-09-09 杭州医学院 Bifunctional molecule based on BCR-ABL protein degradation induced by VHL ligand and preparation method and application thereof

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8957066B2 (en) * 2011-02-28 2015-02-17 Biomarin Pharmaceutical Inc. Histone deacetylase inhibitors
CN107095871A (en) * 2016-02-22 2017-08-29 中国科学院上海巴斯德研究所 Quisinostat, a kind of new efficient antimalarial agent
WO2018017858A1 (en) * 2016-07-20 2018-01-25 The Trustees Of Columbia University In The City Of New York Histone acetyltransferase activators and compositions and uses thereof
CN114409638B (en) * 2022-02-09 2023-02-14 深圳大学 Histone deacetylase 8 selective degradation agent, preparation method and application thereof in antitumor activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1781639B1 (en) * 2004-07-28 2012-01-25 Janssen Pharmaceutica NV Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115028678A (en) * 2022-07-08 2022-09-09 杭州医学院 Bifunctional molecule based on BCR-ABL protein degradation induced by VHL ligand and preparation method and application thereof

Also Published As

Publication number Publication date
PT2066327E (en) 2013-02-06
NZ575030A (en) 2012-07-27
CN101516374B (en) 2013-04-24
ME01514B (en) 2014-04-20
SG177219A1 (en) 2012-01-30
ZA200901818B (en) 2010-05-26
SI2066327T1 (en) 2013-04-30
DK2066327T3 (en) 2013-02-11
CN101516374A (en) 2009-08-26
ES2399670T3 (en) 2013-04-02
BRPI0716992A2 (en) 2013-09-17
RS52638B (en) 2013-06-28

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