ME01514B - Histone deacetylase inhibitors with combined activity on class-l and class-ll B histone deacetylases in combination with proteasome inhibitors - Google Patents
Histone deacetylase inhibitors with combined activity on class-l and class-ll B histone deacetylases in combination with proteasome inhibitorsInfo
- Publication number
- ME01514B ME01514B MEP-2013-15A MEP1513A ME01514B ME 01514 B ME01514 B ME 01514B ME P1513 A MEP1513 A ME P1513A ME 01514 B ME01514 B ME 01514B
- Authority
- ME
- Montenegro
- Prior art keywords
- class
- inhibitors
- histone
- combination
- combined activity
- Prior art date
Links
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Ovaj pronalazak se odnosi na inhibitore histonske deacetilaze (HDAC) sa spojenom aktivnosti protiv histonskih deacetilaza iz klase-I i klase-II. Pronalazak se odnosi na kombinacije i kompozicije koje obuhvataju pomenute inhibitore, kao i na njihovu upotrebu, kao lekove, na primer kao lek koji inhibira hematopoetske tumore poput limfoma i leukemija.The present invention relates to histone deacetylase (HDAC) inhibitors with coupled activity against class-I and class-II histone deacetylases. The invention relates to combinations and compositions comprising said inhibitors as well as their use as medicaments, for example as a medicament that inhibits hematopoietic tumors such as lymphomas and leukemias.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06120726 | 2006-09-15 | ||
US91589507P | 2007-05-03 | 2007-05-03 | |
EP07803397A EP2066327B1 (en) | 2006-09-15 | 2007-09-11 | Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors |
PCT/EP2007/059518 WO2008031817A2 (en) | 2006-09-15 | 2007-09-11 | Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
ME01514B true ME01514B (en) | 2014-04-20 |
Family
ID=41040414
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MEP-2013-15A ME01514B (en) | 2006-09-15 | 2007-09-11 | Histone deacetylase inhibitors with combined activity on class-l and class-ll B histone deacetylases in combination with proteasome inhibitors |
Country Status (12)
Country | Link |
---|---|
CN (1) | CN101516374B (en) |
BR (1) | BRPI0716992A2 (en) |
DK (1) | DK2066327T3 (en) |
ES (1) | ES2399670T3 (en) |
ME (1) | ME01514B (en) |
NZ (1) | NZ575030A (en) |
PT (1) | PT2066327E (en) |
RS (1) | RS52638B (en) |
SG (1) | SG177219A1 (en) |
SI (1) | SI2066327T1 (en) |
UA (1) | UA97249C2 (en) |
ZA (1) | ZA200901818B (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8957066B2 (en) * | 2011-02-28 | 2015-02-17 | Biomarin Pharmaceutical Inc. | Histone deacetylase inhibitors |
CN107095871A (en) * | 2016-02-22 | 2017-08-29 | 中国科学院上海巴斯德研究所 | Quisinostat, a kind of new efficient antimalarial agent |
KR20190030693A (en) * | 2016-07-20 | 2019-03-22 | 더 트러스티이스 오브 콜롬비아 유니버시티 인 더 시티 오브 뉴욕 | Histone acetyltransferase activators and compositions and uses thereof |
CN114409638B (en) * | 2022-02-09 | 2023-02-14 | 深圳大学 | Histone deacetylase 8 selective degradation agent, preparation method and application thereof in antitumor activity |
CN115028678A (en) * | 2022-07-08 | 2022-09-09 | 杭州医学院 | Bifunctional molecule based on BCR-ABL protein degradation induced by VHL ligand and preparation method and application thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006010750A1 (en) * | 2004-07-28 | 2006-02-02 | Janssen Pharmaceutica N.V. | Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase |
-
2007
- 2007-09-11 PT PT78033974T patent/PT2066327E/en unknown
- 2007-09-11 NZ NZ575030A patent/NZ575030A/en unknown
- 2007-09-11 SG SG2011092863A patent/SG177219A1/en unknown
- 2007-09-11 UA UAA200900388A patent/UA97249C2/en unknown
- 2007-09-11 ME MEP-2013-15A patent/ME01514B/en unknown
- 2007-09-11 DK DK07803397.4T patent/DK2066327T3/en active
- 2007-09-11 BR BRPI0716992-2A2A patent/BRPI0716992A2/en not_active Application Discontinuation
- 2007-09-11 SI SI200731143T patent/SI2066327T1/en unknown
- 2007-09-11 ES ES07803397T patent/ES2399670T3/en active Active
- 2007-09-11 RS RS20130038A patent/RS52638B/en unknown
- 2007-09-11 CN CN200780034143.2A patent/CN101516374B/en active Active
-
2009
- 2009-03-13 ZA ZA200901818A patent/ZA200901818B/en unknown
Also Published As
Publication number | Publication date |
---|---|
BRPI0716992A2 (en) | 2013-09-17 |
ZA200901818B (en) | 2010-05-26 |
PT2066327E (en) | 2013-02-06 |
SI2066327T1 (en) | 2013-04-30 |
SG177219A1 (en) | 2012-01-30 |
CN101516374A (en) | 2009-08-26 |
UA97249C2 (en) | 2012-01-25 |
CN101516374B (en) | 2013-04-24 |
RS52638B (en) | 2013-06-28 |
NZ575030A (en) | 2012-07-27 |
DK2066327T3 (en) | 2013-02-11 |
ES2399670T3 (en) | 2013-04-02 |
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