UA97212C2 - Method of differential diagnostics of prostate cancer and benign prostatic hyperplasia - Google Patents
Method of differential diagnostics of prostate cancer and benign prostatic hyperplasiaInfo
- Publication number
- UA97212C2 UA97212C2 UAA201102260A UAA201102260A UA97212C2 UA 97212 C2 UA97212 C2 UA 97212C2 UA A201102260 A UAA201102260 A UA A201102260A UA A201102260 A UAA201102260 A UA A201102260A UA 97212 C2 UA97212 C2 UA 97212C2
- Authority
- UA
- Ukraine
- Prior art keywords
- benign prostatic
- prostatic hyperplasia
- prostate cancer
- prostate
- roc
- Prior art date
Links
Abstract
The invention relates to medicine, in particular to oncourinology, and concerns a method of differential diagnostics of prostate cancer and benign prostatic hyperplasia. According to the invention the patient age and total prostate-specific antigen (PSA) level in blood serum are determined, digital rectal investigation is made, prostate gland sonography with measurement of its volume and biopsy with pathohistological examination is carried out. Tumors are differentiated by Gleason scoring system, and the diagnostic model is verified by ROC-analysis. In addition free:total PSA ratio and prostate-specific antigen density is determined, and probabilityof reliability of benign prostatic hyperplasia prediction in patients with suspicion of prostate cancer is detected by means of binary regression logistic equation. Whenis greater than 0.5, benign prostatic hyperplasia is supposed, and whenless than 0.5, prostate cancer is predicted with such indices of diagnostic test quality as overall sensitivity of 89.5%, specificity of 81.4% and high predictive value according to ROC-curve bounds: area under curve R2=0.94 and significance p=0.0001.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
UAA201102260A UA97212C2 (en) | 2011-02-25 | 2011-02-25 | Method of differential diagnostics of prostate cancer and benign prostatic hyperplasia |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
UAA201102260A UA97212C2 (en) | 2011-02-25 | 2011-02-25 | Method of differential diagnostics of prostate cancer and benign prostatic hyperplasia |
Publications (1)
Publication Number | Publication Date |
---|---|
UA97212C2 true UA97212C2 (en) | 2012-01-10 |
Family
ID=52286229
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA201102260A UA97212C2 (en) | 2011-02-25 | 2011-02-25 | Method of differential diagnostics of prostate cancer and benign prostatic hyperplasia |
Country Status (1)
Country | Link |
---|---|
UA (1) | UA97212C2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112450982A (en) * | 2020-12-09 | 2021-03-09 | 上海市闵行区中心医院 | Qualitative and data scoring system for predicting prostate cancer through B-ultrasonic expression |
-
2011
- 2011-02-25 UA UAA201102260A patent/UA97212C2/en unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112450982A (en) * | 2020-12-09 | 2021-03-09 | 上海市闵行区中心医院 | Qualitative and data scoring system for predicting prostate cancer through B-ultrasonic expression |
CN112450982B (en) * | 2020-12-09 | 2023-03-28 | 上海市闵行区中心医院 | Qualitative and data scoring system for predicting prostate cancer through B-ultrasonic expression |
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