UA97212C2 - Method of differential diagnostics of prostate cancer and benign prostatic hyperplasia - Google Patents

Method of differential diagnostics of prostate cancer and benign prostatic hyperplasia

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Publication number
UA97212C2
UA97212C2 UAA201102260A UAA201102260A UA97212C2 UA 97212 C2 UA97212 C2 UA 97212C2 UA A201102260 A UAA201102260 A UA A201102260A UA A201102260 A UAA201102260 A UA A201102260A UA 97212 C2 UA97212 C2 UA 97212C2
Authority
UA
Ukraine
Prior art keywords
benign prostatic
prostatic hyperplasia
prostate cancer
prostate
roc
Prior art date
Application number
UAA201102260A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Вячеслав Николаевич Григоренко
Олег Владимирович Щербина
Original Assignee
Государственное Учреждение "Институт Урологии Академии Медицинских Наук Украины"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Государственное Учреждение "Институт Урологии Академии Медицинских Наук Украины" filed Critical Государственное Учреждение "Институт Урологии Академии Медицинских Наук Украины"
Priority to UAA201102260A priority Critical patent/UA97212C2/en
Publication of UA97212C2 publication Critical patent/UA97212C2/en

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Abstract

The invention relates to medicine, in particular to oncourinology, and concerns a method of differential diagnostics of prostate cancer and benign prostatic hyperplasia. According to the invention the patient age and total prostate-specific antigen (PSA) level in blood serum are determined, digital rectal investigation is made, prostate gland sonography with measurement of its volume and biopsy with pathohistological examination is carried out. Tumors are differentiated by Gleason scoring system, and the diagnostic model is verified by ROC-analysis. In addition free:total PSA ratio and prostate-specific antigen density is determined, and probabilityof reliability of benign prostatic hyperplasia prediction in patients with suspicion of prostate cancer is detected by means of binary regression logistic equation. Whenis greater than 0.5, benign prostatic hyperplasia is supposed, and whenless than 0.5, prostate cancer is predicted with such indices of diagnostic test quality as overall sensitivity of 89.5%, specificity of 81.4% and high predictive value according to ROC-curve bounds: area under curve R2=0.94 and significance p=0.0001.
UAA201102260A 2011-02-25 2011-02-25 Method of differential diagnostics of prostate cancer and benign prostatic hyperplasia UA97212C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
UAA201102260A UA97212C2 (en) 2011-02-25 2011-02-25 Method of differential diagnostics of prostate cancer and benign prostatic hyperplasia

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
UAA201102260A UA97212C2 (en) 2011-02-25 2011-02-25 Method of differential diagnostics of prostate cancer and benign prostatic hyperplasia

Publications (1)

Publication Number Publication Date
UA97212C2 true UA97212C2 (en) 2012-01-10

Family

ID=52286229

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201102260A UA97212C2 (en) 2011-02-25 2011-02-25 Method of differential diagnostics of prostate cancer and benign prostatic hyperplasia

Country Status (1)

Country Link
UA (1) UA97212C2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112450982A (en) * 2020-12-09 2021-03-09 上海市闵行区中心医院 Qualitative and data scoring system for predicting prostate cancer through B-ultrasonic expression

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112450982A (en) * 2020-12-09 2021-03-09 上海市闵行区中心医院 Qualitative and data scoring system for predicting prostate cancer through B-ultrasonic expression
CN112450982B (en) * 2020-12-09 2023-03-28 上海市闵行区中心医院 Qualitative and data scoring system for predicting prostate cancer through B-ultrasonic expression

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