CN112450982B - Qualitative and data scoring system for predicting prostate cancer through B-ultrasonic expression - Google Patents
Qualitative and data scoring system for predicting prostate cancer through B-ultrasonic expression Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
- A61B8/0833—Detecting organic movements or changes, e.g. tumours, cysts, swellings involving detecting or locating foreign bodies or organic structures
- A61B8/085—Detecting organic movements or changes, e.g. tumours, cysts, swellings involving detecting or locating foreign bodies or organic structures for locating body or organic structures, e.g. tumours, calculi, blood vessels, nodules
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
- A61B8/4411—Device being modular
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/5215—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
- A61B8/5223—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for extracting a diagnostic or physiological parameter from medical diagnostic data
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/0002—Inspection of images, e.g. flaw detection
- G06T7/0012—Biomedical image inspection
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/10—Image acquisition modality
- G06T2207/10132—Ultrasound image
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
- G06T2207/30081—Prostate
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
- G06T2207/30096—Tumor; Lesion
Abstract
The invention relates to the field of data evaluation calculation, in particular to a qualitative and data scoring system for predicting prostate cancer through B-ultrasonic performance, which comprises a B-ultrasonic machine, wherein a port of the B-ultrasonic machine is electrically connected with a data temporary storage module, the data temporary storage module is used for converting an electric signal of the B-ultrasonic machine and temporarily storing data, the data temporary storage module sends the data to an imaging detection module through a network connection module, the imaging detection module is used for displaying the imaging of the B-ultrasonic machine, the imaging detection module is connected with a background system, the background system comprises a scoring module and a PC (personal computer) set, the scoring module comprises a calculation model key-in module, and the calculation model key-in module is used for inputting a formula of evaluation calculation.
Description
Technical Field
The invention relates to the field of data evaluation and calculation, in particular to a qualitative and data scoring system for predicting prostate cancer through B-mode ultrasound expression.
Background
This is a prospective study based on the thyroid scoring system TI-RADS:
the material is prepared by the following steps: the first stage is as follows: retrospectively analyzing the imaging characteristics of 206 prostate puncture patients, analyzing the imaging characteristics, analyzing the correlation between each imaging characteristic and the puncture positive rate, analyzing the correlation between the imaging characteristics, finally selecting the most representative characteristics, and counting a scoring model. The tumor detection rate varies between different fraction intervals. And a second stage: 189 patients were prospectively grouped according to a scoring model and the efficacy of the scoring system in predicting prostate cancer effects was then analyzed.
Prostate cancer is the first tumor of the incidence rate of male tumors at present, psa serves as the only screening means at present, the imaging examination, particularly the B-ultrasonic examination, does not have a unified judgment system at present, the magnetic resonance examination can better reflect the structure between the prostate and the internal and external glands, and has a prediction value on prostate cancer, and the PI-rads score is the imaging judgment standard which is widely applied at present, but the magnetic resonance examination appointment time is long, and in addition, many patients cannot carry out the magnetic resonance examination due to the fact that the bodies of the patients have implants, such as artificial hip joints, cardiac pacemakers and the like, so that the application of the B-ultrasonic examination is relatively quick, the pain and the wound are small, the B-ultrasonic examination based judgment standard is established, and the qualitative prediction of the prostate cancer is helped.
Disclosure of Invention
The invention aims to solve the defects in the background art and provides a qualitative and data scoring system for predicting prostate cancer through B-mode ultrasonic expression.
In order to achieve the above purposes, the technical scheme adopted by the invention is as follows: a qualitative and data scoring system for predicting prostate cancer through B-ultrasonic performance comprises a B-ultrasonic machine, wherein a port of the B-ultrasonic machine is electrically connected with a data temporary storage module, the data temporary storage module is used for converting an electric signal of the B-ultrasonic machine and temporarily storing data, the data temporary storage module sends the data to an imaging detection module through a network connection module, the imaging detection module is used for displaying imaging of the B-ultrasonic machine, the imaging detection module is connected with a background system, the background system comprises a scoring module and a PC (personal computer) set, the scoring module comprises a calculation model key-in module, the calculation model key-in module is used for inputting a formula for evaluation calculation, a port of the calculation model key-in module is connected with a calculation model AUC analysis module, the calculation model AUC analysis module is used for evaluating an AUC value of a numerical value calculated by the calculation formula, a port of the calculation model AUC analysis module is connected with a judgment module, the judgment module is used for judging whether the AUC value reaches the standard, and the judgment module comprises a threshold setting module.
Preferably, the network connection module includes a WIFI module and an I/O connection module, and is used to provide two data transmission modes, namely wireless and limited.
Preferably, the data temporary storage module includes a first processor, a memory group electrically connected to the first processor, a key-in keyboard, and an a/D converter, a port of the a/D converter is connected to a scanner, and a port of the a/D converter is further connected to a port of a B-mode ultrasonic machine, wherein: the memory group is used for directly transmitting information with the first processor, the A/D converter is used for reducing and converting the electrical signal of the B-ultrasonic machine and sending the electrical signal to the first processor, and the scanner is used for detecting the operation of the A/D converter.
Preferably, the imaging detection module comprises a second processor, a first interaction module electrically connected with the second processor, a cache module, a display module and a projector, the first interaction module is used for manually controlling the output of imaging, the cache module is used for storing imaging data, the projector is used for amplifying display imaging, and the display module comprises a display screen.
Preferably, the B-ultrasonic machine comprises a control unit, the control unit is connected with an ultrasonic generator and an ultrasonic receiver, the ultrasonic receiver is used for receiving ultrasonic waves sent by the ultrasonic generator, the control unit is further connected with an acceleration switch and a signal processing module, the acceleration switch is used for controlling the working power of the B-ultrasonic machine, the signal processing module is connected with a frequency division sending module, the signal processing module is used for converting ultrasonic signals into electric signals and transmitting the electric signals to the frequency division sending module, and the frequency division sending module converts the size of the electric signals and sends the electric signals to the data temporary storage module.
Preferably, the B-ultrasonic machine, the data temporary storage module, the imaging detection module and the background system are electrically connected with a power supply device, and the power supply device plays a role in power supply.
Preferably, the power supply device comprises a microcontroller, a current acquisition module, a voltage acquisition module, a time recording module, an alarm module and a storage battery, wherein the current acquisition module is electrically connected with the microcontroller, the voltage acquisition module is used for detecting the current of the circuit, the voltage acquisition module is used for detecting the voltage of the circuit, the time recording module is used for recording the working time, and the alarm module is used for giving an alarm when the current and the voltage are abnormal.
Preferably, the scoring module is connected with a correlation result output module and a storage module, the storage module is used for storing the scoring result, and the correlation result output module is used for matching and outputting the score with the disease condition risk.
A B-ultrasonic scoring standard system is also provided, which is used in the scoring module and comprises the following scoring systems:
the first is that the boundaries of the central zone and the peripheral zone of the prostate in the B-ultrasonic image are divided into 4 scores according to the structure and the definition degree of the boundaries: 1 minute: the central belt and the peripheral belt are clear in structure and clear in boundary; and 2, dividing: the central band and the peripheral band structure and the boundary are not cleared; and 3, dividing: the central belt and the outer peripheral belt are unclear in structure and boundary; and 4, dividing: the boundary structures of the central zone and the peripheral zone are disordered and cannot be distinguished.
The second factor is the hypoechoic bolus in the prostate in the ultrasound B image, which is classified in this term by 3 scores: 1 minute: no low echo optical mass; and 2, dividing: a suspected low-echo bolus; and 3, dividing: a significantly low-echo bolus;
the third is the prostate contour and the degree of the shape rule in the B-mode ultrasound image, which is specifically divided into 2 scores: 1 minute: the shape and the outline of the prostate are regular and smooth; and 2, dividing: the outline of the prostate is irregular, and the edge is rough;
and finally, analyzing the correlation between each parameter and the result, and then combining the weight coefficients to obtain the final score. Each score interval represents a different tumor risk. Or tumor detection rate.
Compared with the prior art, the invention has the following beneficial effects:
1. the invention can be used for detecting and evaluating patients with implants in bodies, such as artificial hip joints, cardiac pacemakers and the like, which can not be used for magnetic resonance examination, and the detection system can be well applied.
2. The system can manually input and update a calculation model, the calculation model can obtain corresponding AUC values by inputting a plurality of case numerical values and calculating through a calculation model AUC analysis module, so as to evaluate the accuracy of the calculation model, a set AUC threshold value is judged through a judgment module, the calculation model can be used for calculation scoring in a scoring module when the calculation model reaches the standard, and meticulous and flexible application is realized.
3. The B-ultrasonic machine respectively converts the ultrasonic signals into electrical signals and reduces the obtained electrical signals to be sent out through the signal processing module and the frequency division sending module, and then the A/D converter in the data temporary storage module is used for carrying out secondary reduction on the electrical signals, so that the burden of a conversion circuit is reduced, and the transmission of the signals of the B-ultrasonic machine is facilitated.
4. The imaging detection system is used for a front-end doctor to observe, the data temporary storage module can select to transmit a data signal to the imaging detection module in a wireless or wired mode, and the background system is used for further processing the obtained B-ultrasonic image, so that the system can not influence the scoring of the scoring module in the process of medical work of patients, the two can be carried out simultaneously, the detection efficiency is effectively improved, and the system is more reasonable.
Drawings
FIG. 1 is a schematic diagram of a qualitative and data scoring system for predicting prostate cancer by B-mode ultrasound expression in accordance with the present invention;
FIG. 2 is a schematic diagram of a power module of a qualitative and data scoring system for predicting prostate cancer by ultrasound B expression in accordance with the present invention;
FIG. 3 is a schematic diagram of a B-mode ultrasound machine of a qualitative and data scoring system for predicting prostate cancer by B-mode ultrasound performance in accordance with the present invention;
FIG. 4 is a schematic diagram of a data staging module of a system for qualitative and data scoring for prostate cancer prediction by ultrasound-B expression according to the present invention;
FIG. 5 is a schematic diagram of an imaging detection module of a qualitative and data scoring system for predicting prostate cancer by B-mode ultrasound expression in accordance with the present invention;
FIG. 6 is a schematic diagram of the prostate median and peripheral zone boundaries in a B-mode ultrasound image of a system for qualitative and data scoring for prostate cancer prediction by B-mode ultrasound performance in accordance with the present invention;
FIG. 7 is a schematic diagram of the hypoechoic bolus in the prostate in a B-mode ultrasound image of a qualitative and data scoring system for predicting prostate cancer by B-mode ultrasound performance in accordance with the present invention;
FIG. 8 is a schematic diagram of the degree of prostate contour and contour regularity in a B-mode ultrasound image of a qualitative and data scoring system for predicting prostate cancer by B-mode ultrasound performance in accordance with the present invention;
Detailed Description
The following description is provided to disclose the invention so as to enable any person skilled in the art to practice the invention. The preferred embodiments in the following description are given by way of example only, and other obvious variations will occur to those skilled in the art.
The qualitative and data scoring system for predicting prostate cancer through type-B ultrasonic expression as shown in fig. 1-8 comprises a type-B ultrasonic machine, a port of the type-B ultrasonic machine is electrically connected with a data temporary storage module, the data temporary storage module is used for converting an electric signal of the type-B ultrasonic machine and temporarily storing data, the data temporary storage module sends the data to an imaging detection module through a network connection module, the imaging detection module is used for displaying imaging of the type-B ultrasonic machine, the imaging detection module is connected with a background system, the background system comprises a scoring module and a PC unit, the scoring module comprises a calculation model key-in module, the calculation model key-in module is used for inputting an evaluation calculation formula, the port of the calculation model key-in module is connected with a calculation model analysis module, the calculation model AUC analysis module is used for evaluating an AUC value of a value calculated by the calculation formula, the calculation model AUC analysis module is connected with an AUC judgment module, the judgment module is used for judging whether the AUC value reaches the standard, and the judgment module comprises a threshold setting module.
The network connection module comprises a WIFI module and an I/O wiring module and is used for providing wireless and limited data transmission modes.
The data temporary storage module comprises a first processor, a memory group electrically connected with the first processor, a key-in keyboard and an A/D converter, wherein the port of the A/D converter is connected with a scanner, and the port of the A/D converter is also connected with the port of a B-ultrasonic machine, wherein: the memory group is used for directly transmitting information with the first processor, the A/D converter is used for reducing and converting the electrical signal of the B-ultrasonic machine and sending the electrical signal to the first processor, and the scanner is used for detecting the operation of the A/D converter.
The imaging detection module comprises a second processor, a first interaction module electrically connected with the second processor, a cache module, a display module and a projector, the first interaction module is used for manually controlling the output of imaging, the cache module is used for storing imaging data, the projector is used for amplifying display imaging, and the display module comprises a display screen.
The B ultrasonic machine comprises a control unit, the control unit is connected with an ultrasonic generator and an ultrasonic receiver, the ultrasonic receiver is used for receiving ultrasonic waves sent by the ultrasonic generator, the control unit is further connected with an acceleration switch and a signal processing module, the acceleration switch is used for controlling the working power of the B ultrasonic machine, the signal processing module is connected with a frequency division sending module, the signal processing module is used for converting ultrasonic signals into electric signals and transmitting the electric signals to the frequency division sending module, and the frequency division sending module is used for converting the electric signals and sending the electric signals to a data temporary storage module.
The B-ultrasonic machine, the data temporary storage module, the imaging detection module and the background system are electrically connected with a power supply device, and the power supply device plays a role in power supply.
The power supply device comprises a microcontroller, a current acquisition module, a voltage acquisition module, a time recording module, an alarm module and a storage battery, wherein the current acquisition module is electrically connected with the microcontroller, the current acquisition module is used for detecting the current of a circuit, the voltage acquisition module is used for detecting the voltage of the circuit, the time recording module is used for recording the working time, and the alarm module is used for alarming when the current and the voltage are abnormal.
The scoring module is connected with a correlation result output module and a storage module, the storage module is used for storing scoring results, and the correlation result output module is used for matching and outputting the scores with the illness state risks.
The invention can be used for detecting and evaluating patients with implants in bodies, such as artificial hip joints, cardiac pacemakers and the like, which can not be used for magnetic resonance examination, and the detection system can be well applied. The calculation model can be manually input and updated in the system, the calculation model can be calculated by inputting a plurality of case values and the calculation model AUC analysis module to obtain corresponding AUC values so as to evaluate the accuracy of the calculation model, the judgment module judges the set AUC threshold value, the calculation and the scoring of the calculation model in the scoring module can be carried out when the calculation model reaches the standard, and the application process is meticulous and flexible. The B-ultrasonic machine respectively converts the ultrasonic signals into electrical signals and reduces the obtained electrical signals to be sent out through the signal processing module and the frequency division sending module, and then the A/D converter in the data temporary storage module is used for carrying out secondary reduction on the electrical signals, so that the burden of a conversion circuit is reduced, and the transmission of the signals of the B-ultrasonic machine is facilitated. Imaging detection system is used for the front end doctor to observe, and data temporary storage module can select to transmit data signal to imaging detection module with wireless or wired mode, and the backstage system is used for the further processing to gained B ultrasonic image, and consequently this system can not influence the grade of grading module at the in-process that the work was carried out is doctorsed and nurses to the disease, and the two can go on simultaneously, has effectively improved detection efficiency, also more reasonable.
A scoring standard system is provided for a scoring module in the invention:
the first is the boundary between the central zone and the peripheral zone of the prostate in the B-mode ultrasound image, which is divided into 4 scores according to the structure and the definition of the boundary. 1 minute: the central band and the peripheral band are clear in structure and clear in boundary (as shown in a in fig. 6); and 2, dividing: central and peripheral band structures and boundary under-cleaning (as shown in fig. 6B); and 3, dividing: central and peripheral bands are poorly structured and bounded (as shown in C in fig. 6); and 4, dividing: the central zone and peripheral zone boundary structures are disordered and indistinguishable (as shown at D in fig. 6).
The second factor is the hypoechoic bolus in the prostate, which is classified specifically in this term by 3 scores. 1 minute: no hypoechoic bolus (shown as a in fig. 7); and 2, dividing: suspected hypoechoic bolus (shown as B in fig. 7); and 3, dividing: a significantly low echo bolus (as shown at C in fig. 7).
The third is the prostate contour and the degree of the shape regularity, which is divided into 2 scores. 1 minute: the prostate has regular and smooth shape and contour (as shown in A in figure 8); and 2, dividing: the prostate contours were irregular and the edges were rough (as shown in fig. 8B).
And finally, analyzing the correlation between each parameter and the result, and then combining the weight coefficients to obtain the final score. Each score interval represents a different tumor risk. Or tumor detection rate.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are merely illustrative of the principles of the invention, but that various changes and modifications may be made without departing from the spirit and scope of the invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (8)
1. A qualitative and data scoring system for predicting prostate cancer by B-mode ultrasound performance, comprising a B-mode ultrasound machine, characterized in that: the port of the B-ultrasonic machine is electrically connected with a data temporary storage module, the data temporary storage module is used for converting an electric signal of the B-ultrasonic machine and temporarily storing data, the data temporary storage module sends the data to an imaging detection module through a network connection module, the imaging detection module is used for displaying imaging of the B-ultrasonic machine, the imaging detection module is connected with a background system, the background system comprises a scoring module and a PC (personal computer) set, the scoring module comprises a calculation model key-in module, the calculation model key-in module is used for inputting a formula for evaluating and calculating, the port of the calculation model key-in module is connected with a calculation model AUC analysis module, the calculation model AUC analysis module is used for evaluating an AUC value of a numerical value calculated by the calculation formula, the port of the calculation model AUC analysis module is connected with a judgment module, the judgment module is used for judging whether the AUC value reaches the standard, and the judgment module comprises a threshold setting module;
the scoring module comprises a scoring standard system, and the scoring standard system comprises the following components:
the first is the boundary of the central zone and the peripheral zone of the prostate in the B-ultrasonic image, which is divided into 4 scores according to the structure and the definition of the boundary: 1 minute: the central belt and the peripheral belt are clear in structure and clear in boundary; and 2, dividing: the central band and the peripheral band structure and the boundary are not cleared; and 3, dividing: the central belt and the outer peripheral belt are unclear in structure and boundary; and 4, dividing: the boundary structures of the central belt and the peripheral belt are disordered and cannot be distinguished;
the second factor is the hypoechoic bolus in the prostate in ultrasound B images, which is classified specifically in this term by 3 scores: 1 minute: no low echo optical mass; and 2, dividing: a suspected low-echo bolus; and 3, dividing: a significantly low-echo bolus;
the third is the prostate contour and the degree of the shape rule in the B-mode ultrasound image, which is specifically divided into 2 scores: 1 minute: the shape and the outline of the prostate are regular and smooth; and 2, dividing: the outline of the prostate is irregular, and the edge is rough;
and finally, obtaining a final score by analyzing the correlation between each parameter and the result and combining the weight coefficient of each parameter and the result, wherein each score interval represents different tumor risk degrees or tumor detection rates.
2. The system of claim 1, wherein the qualitative and data scoring system for predicting prostate cancer by ultrasound-B expression comprises: the network connection module comprises a WIFI module and an I/O wiring module and is used for providing two data transmission modes, namely a wireless mode and a limited mode.
3. The system of claim 1, wherein the qualitative and data scoring system for predicting prostate cancer by ultrasound-B expression comprises: the data temporary storage module comprises a first processor, a memory group electrically connected with the first processor, a key-in keyboard and an A/D converter, wherein the port of the A/D converter is connected with a scanner, and the port of the A/D converter is also connected with the port of a B-ultrasonic machine, wherein: the memory group is used for directly transmitting information with the first processor, the A/D converter is used for reducing and converting the electrical signal of the B-ultrasonic machine and sending the electrical signal to the first processor, and the scanner is used for detecting the operation of the A/D converter.
4. The system of claim 1, wherein the qualitative and data scoring system for prognosticating prostate cancer by ultrasound B expression comprises: the imaging detection module comprises a second processor, a first interaction module electrically connected with the second processor, a cache module, a display module and a projector, wherein the first interaction module is used for manually controlling the output of imaging, the cache module is used for storing imaging data, the projector is used for amplifying display imaging, and the display module comprises a display screen.
5. The system of claim 1, wherein the qualitative and data scoring system for predicting prostate cancer by ultrasound-B expression comprises: the B ultrasonic machine comprises a control unit, the control unit is connected with an ultrasonic generator and an ultrasonic receiver, the ultrasonic receiver is used for receiving ultrasonic waves sent by the ultrasonic generator, the control unit is further connected with an acceleration switch and a signal processing module, the acceleration switch is used for controlling the working power of the B ultrasonic machine, the signal processing module is connected with a frequency division sending module, the signal processing module is used for converting ultrasonic signals into electric signals and transmitting the electric signals to the frequency division sending module, and the frequency division sending module converts the size of the electric signals and sends the electric signals to a data temporary storage module.
6. The system of claim 1, wherein the qualitative and data scoring system for predicting prostate cancer by ultrasound-B expression comprises: the B-ultrasonic machine, the data temporary storage module, the imaging detection module and the background system are electrically connected with a power supply device, and the power supply device plays a role in power supply.
7. The system of claim 6, wherein the qualitative and data scoring system for prognosticating prostate cancer by ultrasound B expression comprises: the power supply device comprises a microcontroller, a current acquisition module, a voltage acquisition module, a time recording module, an alarm module and a storage battery, wherein the current acquisition module is electrically connected with the microcontroller, the voltage acquisition module is used for detecting the current of a circuit, the time recording module is used for recording the voltage of the circuit, the time recording module is used for recording the working time, and the alarm module is used for giving an alarm when the current and the voltage are abnormal.
8. The system of claim 1, wherein the qualitative and data scoring system for predicting prostate cancer by ultrasound-B expression comprises: the scoring module is connected with a correlation result output module and a storage module, the storage module is used for storing scoring results, and the correlation result output module is used for matching and outputting the scores with the illness state risks.
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