UA96598C2 - Substituted isoindoles as bace inhibitors and their use - Google Patents

Substituted isoindoles as bace inhibitors and their use

Info

Publication number
UA96598C2
UA96598C2 UAA200813747A UAA200813747A UA96598C2 UA 96598 C2 UA96598 C2 UA 96598C2 UA A200813747 A UAA200813747 A UA A200813747A UA A200813747 A UAA200813747 A UA A200813747A UA 96598 C2 UA96598 C2 UA 96598C2
Authority
UA
Ukraine
Prior art keywords
bace inhibitors
substituted isoindoles
isoindoles
substituted
novel compounds
Prior art date
Application number
UAA200813747A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Джеймс Арнольд
Стефан Берг
Гианни Чессари
Маилз Конгрив
Фил Эдвардс
Йорг Голенс
Анника Керс
Карин Колмодин
Кристофер Мюррей
Сагил Пател
Лассло Ракос
Дидье Роттисси
Марк Силвестер
Лиселотте Йоверг
Original Assignee
Астразенека Аб
Астекс Терапеутикс Лтд
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Астразенека Аб, Астекс Терапеутикс Лтд filed Critical Астразенека Аб
Publication of UA96598C2 publication Critical patent/UA96598C2/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

This invention relates to novel compounds having the structural formula I and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.(I)
UAA200813747A 2006-06-22 2007-06-20 Substituted isoindoles as bace inhibitors and their use UA96598C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81580006P 2006-06-22 2006-06-22

Publications (1)

Publication Number Publication Date
UA96598C2 true UA96598C2 (en) 2011-11-25

Family

ID=40977655

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200813747A UA96598C2 (en) 2006-06-22 2007-06-20 Substituted isoindoles as bace inhibitors and their use

Country Status (4)

Country Link
CN (1) CN101506162B (en)
SA (1) SA07280338B1 (en)
UA (1) UA96598C2 (en)
ZA (1) ZA200810167B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8415483B2 (en) * 2010-12-22 2013-04-09 Astrazeneca Ab Compounds and their use as BACE inhibitors

Also Published As

Publication number Publication date
SA07280338B1 (en) 2010-11-02
CN101506162A (en) 2009-08-12
ZA200810167B (en) 2009-11-25
CN101506162B (en) 2012-06-27

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