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Priority claimed from GBGB0312896.4Aexternal-prioritypatent/GB0312896D0/en
Application filed by Астразенека Юк ЛімітедfiledCriticalАстразенека Юк Лімітед
Publication of UA89614C2publicationCriticalpatent/UA89614C2/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
An improved process for manufacture of (E-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3N,5S)-3,5-dihydroxyhept-6-enoic acid calcium salt, Formula (1), which is useful for the production of a pharmaceutical useful in the treatment of, inter alia, hypercholesterolemia, hyperlipoproteinemia and atherosclerosis, is described.
UAA200511187A2003-06-052004-06-03Process for the production of the rosuvastatin calcium salt
UA89614C2
(en)
Process for the manufacture of the calcium salt of rosuvastatin (e)-7-[4- (4-fluorophenyl) -6-isopropyl-2-[methyl(methylsulfonyl) amino]pyrimidin -5- yl] (3r, 5s) -3, 5-dihydroxyhept-6-enoic acid and crystalline intermediates thereof
A PROCEDURE FOR THE PREPARATION OF CALCIUM SALT OF ACID (E) -7- [4- (4-FLUOROPHENIL) -6-ISOPROPIL-2- [METHYL (METHYL-SULFONYL) AMINO] PIRIMIDIN-5-IL] (3R , 5S) -3,5-DIHYDROXIHEPT-6-ENOICO AND COMPOUND USED IN SUCH PROCEDURE