UA86986C2 - Purified arabinogalactan-protein (agp) composition - Google Patents
Purified arabinogalactan-protein (agp) compositionInfo
- Publication number
- UA86986C2 UA86986C2 UAA200701654A UAA200701654A UA86986C2 UA 86986 C2 UA86986 C2 UA 86986C2 UA A200701654 A UAA200701654 A UA A200701654A UA A200701654 A UAA200701654 A UA A200701654A UA 86986 C2 UA86986 C2 UA 86986C2
- Authority
- UA
- Ukraine
- Prior art keywords
- agp
- protein
- composition
- extract
- aqueous
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Botany (AREA)
- Rheumatology (AREA)
- Alternative & Traditional Medicine (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Dermatology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Transplantation (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Neurosurgery (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
Abstract
A purified Arabinogalactan-Protein (AGP) composition, having an average molecular weight range between 10 KD to 150 KD, isolated from the leaves and/or stems of Argemone mexicana plant obtainable by a process comprising the steps of: i) extracting 1 part by weight of the leaves and/or stems of Argemone mexicana plant with 1 to 10 parts by weight of water, a C1-3 alcohol or mixtures thereof to obtain an aqueous extract; and partially or completely concentrating or lyophilizing the extract; ii) subjecting the aqueous extract, partially concentrated aqueous extract or an aqueous solution of the completely concentrated or lyophilized extract as obtained in step i) successively to ion exchange chromatography to obtain a neutral aqueous extract; iii) fractionating the neutral aqueous extract obtained in step ii) with n-butanol and separating the aqueous and the n-butanol phases; iv) mixing and agitating the aqueous phases obtained in step iii) with methanol or ethanol, and isolating the precipitated solids to obtain an insoluble fraction; and v) subjecting the insoluble fraction obtained in step iv) to successive gel chromatography and size exclusion chromatography to obtain purified Arabinogalactan-Protein (AGP) composition.Disclosed are a method for isolating Arabinogalactan-Protein (AGP) composition, a pharmaceutical composition comprising a therapeutically effective amount of the purified Arabinogalactan-Protein (AGP), use of a purified Arabinogalactan-Protein (AGP) and composition.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/931,814 US7601368B2 (en) | 2004-09-01 | 2004-09-01 | Purified Arabinogalactan-Protein (AGP) composition useful in the treatment psoriasis and other disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA86986C2 true UA86986C2 (en) | 2009-06-10 |
Family
ID=35943518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200701654A UA86986C2 (en) | 2004-09-01 | 2005-04-26 | Purified arabinogalactan-protein (agp) composition |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US7601368B2 (en) |
| EP (1) | EP1789439B1 (en) |
| JP (1) | JP2008511613A (en) |
| KR (1) | KR20070059062A (en) |
| CN (1) | CN101044161A (en) |
| AP (1) | AP2007003929A0 (en) |
| AT (1) | ATE452142T1 (en) |
| AU (1) | AU2005278780A1 (en) |
| BR (1) | BRPI0514347A (en) |
| CA (1) | CA2577134A1 (en) |
| DE (1) | DE602005018375D1 (en) |
| EA (1) | EA012208B1 (en) |
| IL (1) | IL181230A0 (en) |
| MX (1) | MX2007002428A (en) |
| NO (1) | NO20071120L (en) |
| TN (1) | TNSN07079A1 (en) |
| UA (1) | UA86986C2 (en) |
| WO (1) | WO2006025068A1 (en) |
| ZA (1) | ZA200701311B (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2399993T3 (en) | 2007-03-02 | 2013-04-04 | Protectimmun Gmbh | Pharmaceutical composition for protection against allergies and inflammatory diseases |
| FR2938192B1 (en) | 2008-11-07 | 2012-08-24 | Expanscience Lab | NEW ANTI-STRETCH ACTIVE INGREDIENTS AND COMPOSITIONS COMPRISING THE SAME |
| EP2346512A1 (en) * | 2008-08-16 | 2011-07-27 | Protectimmun GmbH | Composition for prevention and treatment of allergic and/or inflammatory diseases |
| WO2011139168A1 (en) * | 2010-05-05 | 2011-11-10 | Comvita New Zealand Limited | Immunostimulatory compositions and methods of use thereof |
| FR2975004B1 (en) * | 2011-05-13 | 2013-06-28 | Expanscience Lab | NEW ANTI-REDNESS ACTIVE INGREDIENTS AND COSMETIC COMPOSITIONS COMPRISING THE SAME |
| ITMI20112216A1 (en) | 2011-12-05 | 2013-06-06 | Fond Salvatore Maugeri Clinic A Del Lavoro E | COMPOSITION INCLUDING A CHELIDONIUM MAJUS AND COPAIBA EXTRACT AND ITS USE FOR THE TREATMENT OF CUTANEOUS DYSFUNCTIONS |
| WO2014190398A1 (en) * | 2013-05-31 | 2014-12-04 | The University Of Melbourne | Inhibition of amyloid fibril formation |
| US11179407B2 (en) | 2015-12-01 | 2021-11-23 | Forschungszentrum Borstel Leibniz-Zentrum Für Medizin Und Biowissenshaften | Method for synthetically producing arabinogalactan compounds derived from plants and uses of said compounds for the prophylaxis of allergic reactions |
| EP3176175B1 (en) | 2015-12-01 | 2020-07-01 | Ruhr-Universität Bochum | Method for synthetically producing arabinogalactan compounds derived from plants and uses of said compounds for the prophylaxis of allergic reactions |
| EP4166145A1 (en) | 2016-02-12 | 2023-04-19 | Laimu Corporation | Nerve growth promoter and method for producing same, internal preparation, medium additive, cell dilution additive, medium, cell dilution, antioxidant and method for producing same, external preparation, and wound treatment agent and method for producing same |
| JP6230638B2 (en) * | 2016-02-12 | 2017-11-15 | 株式会社らいむ | Nerve elongation promoter, internal medicine, medium additive, cell diluent additive, medium and cell diluent |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4818533A (en) * | 1985-07-09 | 1989-04-04 | Vipont Pharmaceutical, Inc. | Production of high purity alkaloids |
| US5494671A (en) * | 1990-08-27 | 1996-02-27 | The United States Of America As Represented By The Department Of Health And Human Services | C-terminally truncated dengue and Japanese encephalitis virus envelope proteins |
| JP3177642B2 (en) * | 1991-09-10 | 2001-06-18 | ライオン株式会社 | Antiandrogens |
| EP1200482A1 (en) | 1999-06-30 | 2002-05-02 | Pharmagenesis, Inc. | Hematopoietic arabinogalactan composition |
| EP1467745A2 (en) * | 2002-01-10 | 2004-10-20 | Lupin Limited | Herbal composition for treating various disorders including psoriasis, a process for preparation thereof and method for treatment of such disorders |
-
2004
- 2004-09-01 US US10/931,814 patent/US7601368B2/en not_active Expired - Fee Related
-
2005
- 2005-04-26 DE DE602005018375T patent/DE602005018375D1/en not_active Expired - Fee Related
- 2005-04-26 AU AU2005278780A patent/AU2005278780A1/en not_active Abandoned
- 2005-04-26 AT AT05775653T patent/ATE452142T1/en not_active IP Right Cessation
- 2005-04-26 BR BRPI0514347-0A patent/BRPI0514347A/en not_active IP Right Cessation
- 2005-04-26 UA UAA200701654A patent/UA86986C2/en unknown
- 2005-04-26 WO PCT/IN2005/000132 patent/WO2006025068A1/en active Application Filing
- 2005-04-26 JP JP2007529142A patent/JP2008511613A/en active Pending
- 2005-04-26 AP AP2007003929A patent/AP2007003929A0/en unknown
- 2005-04-26 CN CNA2005800355154A patent/CN101044161A/en active Pending
- 2005-04-26 EA EA200700532A patent/EA012208B1/en not_active IP Right Cessation
- 2005-04-26 KR KR1020077003989A patent/KR20070059062A/en not_active Application Discontinuation
- 2005-04-26 CA CA002577134A patent/CA2577134A1/en not_active Abandoned
- 2005-04-26 EP EP05775653A patent/EP1789439B1/en active Active
- 2005-04-26 MX MX2007002428A patent/MX2007002428A/en unknown
-
2007
- 2007-02-08 IL IL181230A patent/IL181230A0/en unknown
- 2007-02-14 ZA ZA200701311A patent/ZA200701311B/en unknown
- 2007-02-27 NO NO20071120A patent/NO20071120L/en not_active Application Discontinuation
- 2007-02-28 TN TNP2007000079A patent/TNSN07079A1/en unknown
-
2009
- 2009-07-02 US US12/497,217 patent/US20100330650A1/en not_active Abandoned
- 2009-07-02 US US12/497,148 patent/US20090270330A1/en not_active Abandoned
- 2009-07-02 US US12/496,924 patent/US20090264341A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MX2007002428A (en) | 2007-05-11 |
| EP1789439B1 (en) | 2009-12-16 |
| WO2006025068A8 (en) | 2006-04-20 |
| KR20070059062A (en) | 2007-06-11 |
| EA200700532A1 (en) | 2007-08-31 |
| NO20071120L (en) | 2007-05-14 |
| US7601368B2 (en) | 2009-10-13 |
| ATE452142T1 (en) | 2010-01-15 |
| CA2577134A1 (en) | 2006-03-09 |
| ZA200701311B (en) | 2009-08-26 |
| US20090264341A1 (en) | 2009-10-22 |
| IL181230A0 (en) | 2007-07-04 |
| JP2008511613A (en) | 2008-04-17 |
| US20090270330A1 (en) | 2009-10-29 |
| US20060045930A1 (en) | 2006-03-02 |
| AP2007003929A0 (en) | 2007-02-28 |
| BRPI0514347A (en) | 2008-06-10 |
| TNSN07079A1 (en) | 2008-06-02 |
| US20100330650A1 (en) | 2010-12-30 |
| EA012208B1 (en) | 2009-08-28 |
| EP1789439A1 (en) | 2007-05-30 |
| AU2005278780A1 (en) | 2006-03-09 |
| WO2006025068A1 (en) | 2006-03-09 |
| CN101044161A (en) | 2007-09-26 |
| DE602005018375D1 (en) | 2010-01-28 |
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