UA83484C2 - Спосіб лікування раку грудей комбінацією похідного рапаміцину і інгібітора ароматази - летрозолу, фармацевтична композиція - Google Patents
Спосіб лікування раку грудей комбінацією похідного рапаміцину і інгібітора ароматази - летрозолу, фармацевтична композиція Download PDFInfo
- Publication number
- UA83484C2 UA83484C2 UAA200509283A UA2005009283A UA83484C2 UA 83484 C2 UA83484 C2 UA 83484C2 UA A200509283 A UAA200509283 A UA A200509283A UA 2005009283 A UA2005009283 A UA 2005009283A UA 83484 C2 UA83484 C2 UA 83484C2
- Authority
- UA
- Ukraine
- Prior art keywords
- aai
- aza
- miyiza
- mkr
- aaia
- Prior art date
Links
- 229940122815 Aromatase inhibitor Drugs 0.000 title abstract 2
- 239000003886 aromatase inhibitor Substances 0.000 title abstract 2
- 206010006187 Breast cancer Diseases 0.000 title 1
- 208000026310 Breast neoplasm Diseases 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical class C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 title 1
- 208000006123 Myiasis Diseases 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- CBPNZQVSJQDFBE-FUXHJELOSA-N Temsirolimus Chemical compound C1C[C@@H](OC(=O)C(C)(CO)CO)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 CBPNZQVSJQDFBE-FUXHJELOSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- HKVAMNSJSFKALM-CPXURSODSA-N everolimus Chemical compound C1C[C@@H](OCCO)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)\C(C)=C\C=C\C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 HKVAMNSJSFKALM-CPXURSODSA-N 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229960000235 temsirolimus Drugs 0.000 abstract 1
- 235000013929 Psidium pyriferum Nutrition 0.000 description 2
- 244000236580 Psidium pyriferum Species 0.000 description 2
- 229940106943 azor Drugs 0.000 description 2
- XGDRLCRGKUCBQL-UHFFFAOYSA-N 1h-imidazole-4,5-dicarbonitrile Chemical compound N#CC=1N=CNC=1C#N XGDRLCRGKUCBQL-UHFFFAOYSA-N 0.000 description 1
- 241000223477 Abea Species 0.000 description 1
- 101100109406 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) aga-1 gene Proteins 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45228903P | 2003-03-05 | 2003-03-05 | |
| PCT/US2004/006354 WO2004078133A2 (en) | 2003-03-05 | 2004-03-01 | Antineoplastic combinations comprising a rapamycin derivative and an aromatase inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA83484C2 true UA83484C2 (uk) | 2008-07-25 |
Family
ID=32962706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200509283A UA83484C2 (uk) | 2003-03-05 | 2004-01-03 | Спосіб лікування раку грудей комбінацією похідного рапаміцину і інгібітора ароматази - летрозолу, фармацевтична композиція |
Country Status (20)
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI233359B (en) * | 2001-04-06 | 2005-06-01 | Wyeth Corp | Pharmaceutical composition for treating neoplasm |
| US20020198137A1 (en) * | 2001-06-01 | 2002-12-26 | Wyeth | Antineoplastic combinations |
| RU2345772C2 (ru) * | 2003-07-25 | 2009-02-10 | Уайт | Лиофилизированные композиции cci-779 |
| ES2298861T3 (es) * | 2004-01-08 | 2008-05-16 | Wyeth | Composicion farmaceutica que puede obtenerse mediante compresion directa para la administracion oral de cci-779. |
| AR047988A1 (es) * | 2004-03-11 | 2006-03-15 | Wyeth Corp | Combinaciones antineoplásicas de cci-779 y rituximab |
| KR20070070184A (ko) * | 2004-10-28 | 2007-07-03 | 와이어쓰 | 자궁근종의 치료에 있어서 ｍＴＯＲ 억제제의 용도 |
| MX2007009317A (es) | 2005-02-03 | 2008-01-30 | Gen Hospital Corp | Metodo para tratar cancer resistente a gefitinib. |
| CN103110948A (zh) | 2005-11-04 | 2013-05-22 | 惠氏公司 | mTOR抑制剂、赫赛汀和/或HKI-272的抗肿瘤组合 |
| JP2009516671A (ja) * | 2005-11-21 | 2009-04-23 | ノバルティス アクチエンゲゼルシャフト | ｍＴＯＲ阻害剤を使用する神経内分泌腫瘍処置 |
| DE102006008074B4 (de) * | 2006-02-22 | 2013-08-14 | RUHR-UNIVERSITäT BOCHUM | Behandlung von Krebs mit Geruchsrezeptor-Liganden |
| DE102006011507A1 (de) * | 2006-03-14 | 2007-09-20 | Lts Lohmann Therapie-Systeme Ag | Wirkstoffbeladene Nanopartikel auf Basis hydrophiler Proteine |
| WO2008022256A2 (en) * | 2006-08-16 | 2008-02-21 | Blagosklonny Mikhail V | Methods and compositions for preventing or treating age-related diseases |
| US8414910B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
| US9700704B2 (en) | 2006-11-20 | 2017-07-11 | Lutonix, Inc. | Drug releasing coatings for balloon catheters |
| US9737640B2 (en) | 2006-11-20 | 2017-08-22 | Lutonix, Inc. | Drug releasing coatings for medical devices |
| US8414525B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
| US8414909B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
| US8998846B2 (en) | 2006-11-20 | 2015-04-07 | Lutonix, Inc. | Drug releasing coatings for balloon catheters |
| US8414526B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids |
| US20080276935A1 (en) | 2006-11-20 | 2008-11-13 | Lixiao Wang | Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs |
| US8425459B2 (en) | 2006-11-20 | 2013-04-23 | Lutonix, Inc. | Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent |
| TW200901989A (en) * | 2007-04-10 | 2009-01-16 | Wyeth Corp | Anti-tumor activity of CCI-779 in papillary renal cell cancer |
| US8022216B2 (en) | 2007-10-17 | 2011-09-20 | Wyeth Llc | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof |
| WO2010008744A2 (en) | 2008-06-17 | 2010-01-21 | Wyeth | Antineoplastic combinations containing hki-272 and vinorelbine |
| RU2498804C2 (ru) | 2008-08-04 | 2013-11-20 | ВАЙЕТ ЭлЭлСи | Противоопухолевые комбинации из 4-анилино-3-цианохинолинов и капецитабина |
| WO2010024898A2 (en) | 2008-08-29 | 2010-03-04 | Lutonix, Inc. | Methods and apparatuses for coating balloon catheters |
| CA2743242A1 (en) * | 2008-11-11 | 2010-05-20 | Eli Lilly And Company | P70 s6 kinase inhibitor and mtor inhibitor combination therapy |
| JP5992325B2 (ja) | 2009-04-06 | 2016-09-14 | ワイス・エルエルシー | 乳癌のための、ネラチニブを活用する治療計画 |
| CN102612564B (zh) | 2009-04-10 | 2015-08-26 | 齐海燕 | 新的抗衰老试剂及其鉴别方法 |
| ES2694582T3 (es) | 2011-01-31 | 2018-12-21 | Lucolas-M.D. Ltd. | Combinaciones de inhibidores de aromatasa y antioxidantes |
| US9682066B2 (en) * | 2012-12-04 | 2017-06-20 | University Of Cincinnati | Methods of treating primary brain tumors by administering letrozole |
| WO2015014284A1 (zh) * | 2013-07-31 | 2015-02-05 | 北京盛诺基医药科技有限公司 | 一种乳腺癌的治疗方法 |
| MX381173B (es) | 2013-10-08 | 2025-03-12 | Ai Therapeutics Inc | Rapamicina para el tratamiento de linfangioleiomiomatosis. |
| MX394266B (es) | 2014-04-04 | 2025-03-24 | Ai Therapeutics Inc | Una formulacion de rapamicina inhalable para tratar afecciones relacionadas con la edad. |
| WO2016057712A1 (en) | 2014-10-07 | 2016-04-14 | Lam Therapeutics, Inc. | An inhalable rapamycin formulation for the treatment of pulmonary hypertension |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5A (en) * | 1836-08-10 | Thomas Blanchard | Machine for mortising solid wooden shells of ships' tackle-blocks | |
| US6A (en) * | 1836-08-10 | Thomas Blanchard | Machine for forming end pieces of plank blocks for ships | |
| ZA737247B (en) * | 1972-09-29 | 1975-04-30 | Ayerst Mckenna & Harrison | Rapamycin and process of preparation |
| US3993749A (en) * | 1974-04-12 | 1976-11-23 | Ayerst Mckenna And Harrison Ltd. | Rapamycin and process of preparation |
| US5206018A (en) * | 1978-11-03 | 1993-04-27 | Ayerst, Mckenna & Harrison, Inc. | Use of rapamycin in treatment of tumors |
| US5066493A (en) * | 1978-11-03 | 1991-11-19 | American Home Products Corporation | Rapamycin in treatment of tumors |
| US4885171A (en) * | 1978-11-03 | 1989-12-05 | American Home Products Corporation | Use of rapamycin in treatment of certain tumors |
| US4401653A (en) * | 1981-03-09 | 1983-08-30 | Ayerst, Mckenna & Harrison Inc. | Combination of rapamycin and picibanil for the treatment of tumors |
| US5100899A (en) * | 1989-06-06 | 1992-03-31 | Roy Calne | Methods of inhibiting transplant rejection in mammals using rapamycin and derivatives and prodrugs thereof |
| US5078999A (en) * | 1991-02-22 | 1992-01-07 | American Home Products Corporation | Method of treating systemic lupus erythematosus |
| US5080899A (en) * | 1991-02-22 | 1992-01-14 | American Home Products Corporation | Method of treating pulmonary inflammation |
| US5321009A (en) * | 1991-04-03 | 1994-06-14 | American Home Products Corporation | Method of treating diabetes |
| ZA924953B (en) * | 1991-07-25 | 1993-04-28 | Univ Louisville Res Found | Method of treating ocular inflammation |
| US5286730A (en) * | 1991-09-17 | 1994-02-15 | American Home Products Corporation | Method of treating immunoinflammatory disease |
| US5286731A (en) * | 1991-09-17 | 1994-02-15 | American Home Products Corporation | Method of treating immunoinflammatory bowel disease |
| US5516781A (en) * | 1992-01-09 | 1996-05-14 | American Home Products Corporation | Method of treating restenosis with rapamycin |
| US5288711A (en) * | 1992-04-28 | 1994-02-22 | American Home Products Corporation | Method of treating hyperproliferative vascular disease |
| US5302584A (en) * | 1992-10-13 | 1994-04-12 | American Home Products Corporation | Carbamates of rapamycin |
| US5362718A (en) * | 1994-04-18 | 1994-11-08 | American Home Products Corporation | Rapamycin hydroxyesters |
| US5561138A (en) * | 1994-12-13 | 1996-10-01 | American Home Products Corporation | Method of treating anemia |
| US5496832A (en) * | 1995-03-09 | 1996-03-05 | American Home Products Corporation | Method of treating cardiac inflammatory disease |
| US6002008A (en) * | 1997-04-03 | 1999-12-14 | American Cyanamid Company | Substituted 3-cyano quinolines |
| US6277983B1 (en) * | 2000-09-27 | 2001-08-21 | American Home Products Corporation | Regioselective synthesis of rapamycin derivatives |
| CA2416976C (en) * | 2000-08-11 | 2008-05-20 | Wyeth | Treatment of estrogen receptor positive carcinoma with a rapamycin and an antiestrogen |
| TWI286074B (en) * | 2000-11-15 | 2007-09-01 | Wyeth Corp | Pharmaceutical composition containing CCI-779 as an antineoplastic agent |
| PL231418B1 (pl) * | 2001-02-19 | 2019-02-28 | Novartis Ag | 40-O-( 2-hydroksyetylo)- rapamycyna do zastosowania w leczeniu guzów litych płuc, innych niż nowotwór tkanki limfatycznej |
| TWI296196B (en) * | 2001-04-06 | 2008-05-01 | Wyeth Corp | Antineoplastic combinations |
| TWI233359B (en) * | 2001-04-06 | 2005-06-01 | Wyeth Corp | Pharmaceutical composition for treating neoplasm |
| MXPA03009092A (es) * | 2001-04-06 | 2004-02-12 | Wyeth Corp | COMBINACIONES DE ANTINEOPLaSICOS COMO RAPAMICINA CON GEMCITABINA O FLUOROURACILO. |
| CN100496485C (zh) * | 2001-06-01 | 2009-06-10 | 惠氏公司 | 抗肿瘤组合 |
| US20030008923A1 (en) * | 2001-06-01 | 2003-01-09 | Wyeth | Antineoplastic combinations |
| UA77200C2 (en) * | 2001-08-07 | 2006-11-15 | Wyeth Corp | Antineoplastic combination of cci-779 and bkb-569 |
-
2004
- 2004-01-03 UA UAA200509283A patent/UA83484C2/uk unknown
- 2004-02-26 AR ARP040100603A patent/AR043403A1/es unknown
- 2004-03-01 KR KR1020057016528A patent/KR20050109965A/ko not_active Ceased
- 2004-03-01 AU AU2004218439A patent/AU2004218439A1/en not_active Withdrawn
- 2004-03-01 JP JP2006509002A patent/JP2006519862A/ja active Pending
- 2004-03-01 CN CNA200480005869XA patent/CN1756549A/zh active Pending
- 2004-03-01 US US10/790,488 patent/US20040176339A1/en not_active Abandoned
- 2004-03-01 WO PCT/US2004/006354 patent/WO2004078133A2/en not_active Ceased
- 2004-03-01 MX MXPA05009246A patent/MXPA05009246A/es not_active Application Discontinuation
- 2004-03-01 NZ NZ542738A patent/NZ542738A/xx unknown
- 2004-03-01 CA CA002516353A patent/CA2516353A1/en not_active Abandoned
- 2004-03-01 EP EP04716169A patent/EP1603561A2/en not_active Withdrawn
- 2004-03-01 BR BRPI0408024-6A patent/BRPI0408024A/pt not_active IP Right Cessation
- 2004-03-01 RU RU2005130767/14A patent/RU2355399C2/ru not_active IP Right Cessation
- 2004-03-02 TW TW093105371A patent/TW200529829A/zh unknown
-
2005
- 2005-08-12 CR CR7942A patent/CR7942A/es not_active Application Discontinuation
- 2005-09-01 NI NI200500148A patent/NI200500148A/es unknown
- 2005-09-05 EC EC2005006001A patent/ECSP056001A/es unknown
- 2005-09-06 NO NO20054133A patent/NO20054133L/no not_active Application Discontinuation
- 2005-10-04 ZA ZA200508029A patent/ZA200508029B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CR7942A (es) | 2006-02-07 |
| AR043403A1 (es) | 2005-07-27 |
| RU2355399C2 (ru) | 2009-05-20 |
| WO2004078133A2 (en) | 2004-09-16 |
| JP2006519862A (ja) | 2006-08-31 |
| NO20054133L (no) | 2005-10-03 |
| MXPA05009246A (es) | 2005-10-19 |
| NI200500148A (es) | 2006-03-30 |
| KR20050109965A (ko) | 2005-11-22 |
| AU2004218439A1 (en) | 2004-09-16 |
| CA2516353A1 (en) | 2004-09-16 |
| RU2005130767A (ru) | 2006-02-10 |
| NO20054133D0 (no) | 2005-09-06 |
| WO2004078133A3 (en) | 2004-11-11 |
| NZ542738A (en) | 2009-02-28 |
| WO2004078133A8 (en) | 2005-09-01 |
| TW200529829A (en) | 2005-09-16 |
| BRPI0408024A (pt) | 2006-02-14 |
| CN1756549A (zh) | 2006-04-05 |
| ZA200508029B (en) | 2007-04-25 |
| US20040176339A1 (en) | 2004-09-09 |
| ECSP056001A (es) | 2006-01-27 |
| EP1603561A2 (en) | 2005-12-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UA83484C2 (uk) | Спосіб лікування раку грудей комбінацією похідного рапаміцину і інгібітора ароматази - летрозолу, фармацевтична композиція | |
| ES2404563T3 (es) | Ampliación estereofónica | |
| US3894195A (en) | Method of and apparatus for aiding hearing and the like | |
| AU2002343734A1 (en) | Edible film | |
| GB0029918D0 (en) | Layered materials | |
| CA2476377A1 (en) | Earphone structure with a composite sound field | |
| AU2001282698A1 (en) | Semi-permeable membrane, method for providing electric power and a device | |
| GB0128936D0 (en) | Wound dressings | |
| MX143125A (es) | Una banda de transmision de fuerza mejorada | |
| AU2002353062A8 (en) | Protected underwire | |
| ATE426304T1 (de) | Kopfhírer | |
| MX345015B (es) | Envolturas de tapones desintegrables y sus aplicaciones. | |
| ES2063326T3 (es) | Conjugados de polimixina. | |
| GB1516845A (en) | Vapour release pack | |
| ES413906A1 (es) | Mejoras en la fabricacion de imanes permanentes. | |
| ES2192275T3 (es) | Materiales en banda transpirables que tienen textura a manera de tejido. | |
| PL361179A1 (en) | Treatment of cancers | |
| WO2020099868A3 (en) | High strength porous cement-based materials | |
| AU2003225567A1 (en) | Desynchronizer having ram based shared digital phase locked loops and sonet high density demapper incorporating same | |
| NZ515386A (en) | Ceramic wound treatment device | |
| DK144825C (da) | Middel i form af en fast genstand til vedvarende frigoerelse af et aktivt materiale og fremgangsmaade til fremstilling af midlet | |
| Vaculovschi et al. | Employment in the Republic of Moldova in the context of the implementation of the national employment strategy 2017-2021 | |
| GB202312329D0 (en) | Elephant ear bag / I'm back | |
| Davydov et al. | The resection of tracheal bifurcation for carcinomas | |
| JP3101603U (ja) | 消炎鎮痛補助用貼付材 |